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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 4.

Teaching NeuroImages: MRI appearances of Lhermitte-Duclos disease
A 48-year-old woman was admitted with a 3-year history of intermittent dizziness and unstable gait. Cranial MRI demonstrated a laminated lesion of T2 hyperintensity and T1 hypointensity involving the left cerebellar hemisphere, which appeared enlarged (figure, A and B). Secondary hydrocephalus and Chiari I malformation were observed. Because the striated appearance on MRI was characteristic of Lhermitte-Duclos disease,1 presurgical diagnosis was made. Total resection of this lesion was performed, and histopathologic evaluation confirmed the diagnosis (figure, C and D). Follow-up neuroradiologic studies revealed no recurren...
Source: Neurology - February 4, 2013 Category: Neurology Authors: Wei, G., Liu, S., Wu, Y., Kang, X., Li, T. Tags: Hydrocephalus, MRI, Gait disorders/ataxia, Primary brain tumor, All Pain RESIDENT AND FELLOW SECTION Source Type: research

Development of Simultaneous Pitch Encoding: Infants Show a High Voice Superiority Effect
Infants must learn to make sense of real-world auditory environments containing simultaneous and overlapping sounds. In adults, event-related potential studies have demonstrated the existence of separate preattentive memory traces for concurrent note sequences and revealed perceptual dominance for encoding of the voice with higher fundamental frequency of 2 simultaneous tones or melodies. Here, we presented 2 simultaneous streams of notes (15 semitones apart) to 7-month-old infants. On 50% of trials, either the higher or the lower note was modified by one semitone, up or down, leaving 50% standard trials. Infants showed mi...
Source: Cerebral Cortex - February 4, 2013 Category: Neurology Authors: Marie, C., Trainor, L. J. Tags: Articles Source Type: research

Is insufficient knowledge of epilepsy the reason for low levels of healthcare in the Lao PDR?
Conclusions: The low level of knowledge of epilepsy on the part of health workers may be contributing to the wide treatment gap in the Lao PDR. Improving knowledge of this disease and increasing the availability of antiepileptic drugs will reduce misconceptions about epilepsy, thus encouraging more PWE to seek treatment. Community-based educational programs and extensive advocacy for people with epilepsy only began in 2009.
Source: BMC Health Services Research - February 4, 2013 Category: Journals (General) Authors: Aina HarimananaPhetvongsinh ChivorakulVimalay SouvongPierre-Marie PreuxHubert Barennes Source Type: research

Factors affecting unmet need for family planning in eastern Sudan
Conclusions: Unmet need for family planning in Eastern Sudan was significantly higher among women with less than secondary education. Also; it is influenced by couple's educational status and woman's occupation. The results of this study necessitate the need for the programme managers to take into account the concept of reproductive health education.
Source: BMC Public Health - Latest articles - February 4, 2013 Category: Consumer Health News Authors: Abdel AliAmira Okud Source Type: research

Exploring the perspectives and experiences of health workers at primary health facilities in Kenya following training.
Conclusion: Enhanced health worker skills conferred by the mental health training programme may be responsible for the significant improvement in outcome of patients in the intervention clinics found in the randomised controlled trial, despite the general shortage of medicines and other health system weaknesses. These findings suggest that strengthening mental health training for primary care staff is worthwhile even where health systems are not strong and where the medicine supply cannot be guaranteed.Trial registrationISRCTN 53515024
Source: International Journal of Mental Health Systems - February 4, 2013 Category: Psychiatry Authors: Rachel JenkinsCaleb OthienoStephen OkeyoJulyan AruwaJan WallcraftBen Jenkins Source Type: research

Influence of personal and environmental factors on mental health in a sample of Austrian survivors of World War II with regard to PTSD: is it resilience?
Conclusions: Our results show no clear picture of factors constituting resilience. Instead, most aspects of resilience rather appeared to be concomitants or consequences of PTSD and non-PTSD. However, special attention should be placed on a challenge-oriented and humorous attitude towards stress in future definitions of resilience.
Source: BMC Psychiatry - Latest articles - February 4, 2013 Category: Psychiatry Authors: Ulrich TranTobias GlückBrigitte Lueger-Schuster Source Type: research

Socioeconomic factors from midlife predict mobility limitation and depressed mood three decades later findings from the AGES-Reykjavik study
Conclusion: Socioeconomic factors from midlife and from childhood affect mobility limitation and depressed mood in old age. Prevention of health problems in old age should begin as early as midlife. (187)
Source: BMC Public Health - Latest articles - February 4, 2013 Category: Consumer Health News Authors: Daniëlle GroffenAnnemarie KosterHans BosmaMarjan van den AkkerThor AspelundKristín SiggeirsdóttirGertrudis KempenJacques van EijkGudny EiriksdottirPálmi JónssonLenore LaunerVilmundur GudnasonTamara Harris Source Type: research

Validation of an information--motivation--behavioral skills model of self-care among Chinese adults with type 2 diabetes
Conclusions: Consistent with the IMB model, having better provider-patient communication, having social support, and having higher self-efficacy was associated with performing diabetes self-care behaviors; and these behaviors were directly linked to lipid control. The findings indicate that diabetes education programs should including strategies enhancing patients' knowledge, motivation and behavioral skills to effect behavior change.
Source: BMC Public Health - Latest articles - February 4, 2013 Category: Consumer Health News Authors: Junling GaoJingli WangYaocheng ZhuJinming Yu Source Type: research

Cross-protective immune responses elicited by live attenuated influenza vaccines.
Abstract The desired effect of vaccination is to elicit protective immune responses against infection with pathogenic agents. An inactivated influenza vaccine is able to induce the neutralizing antibodies directed primarily against two surface antigens, hemagglutinin and neuraminidase. These two antigens undergo frequent antigenic drift and hence necessitate the annual update of a new vaccine strain. Besides the antigenic drift, the unpredictable emergence of the pandemic influenza strain, as seen in the 2009 pandemic H1N1, underscores the development of a new influenza vaccine that elicits broadly protective immun...
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Jang YH, Seong BL Tags: Yonsei Med J Source Type: research

Metabolic syndrome with hyperglycemia and the risk of ischemic stroke.
Conclusion: In Asian population, patients with MetSyn accompanied by T2DM are at the greatest risk for acute non-embolic stroke. Additionally, IFG was not observed to be associated with an increased risk for MetSyn-related ischemic stroke. PMID: 23364957 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Li M, Li Y, Liu J Tags: Yonsei Med J Source Type: research

The influence of anti-platelet resistance on the development of cerebral ischemic lesion after carotid artery stenting.
Conclusion: Anti-platelet resistance can be used to predict new ischemic lesions after CAS. Anti-platelet resistance should be evaluated in all patients prior to CAS to prevent ischemic complications related to CAS. PMID: 23364958 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Song TJ, Suh SH, Min PK, Kim DJ, Kim BM, Heo JH, Kim YD, Lee KY Tags: Yonsei Med J Source Type: research

Hemodynamic Instability during Carotid Angioplasty and Stenting-Relationship of Calcified Plaque and Its Characteristics.
Conclusion: The calcification of plaque is a predictable factor of HDI during CAS, and its extensive and eccentric calcified plaques may be related to prolonged HDI. PMID: 23364959 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Jeon JS, Sheen SH, Hwang G Tags: Yonsei Med J Source Type: research

Beneficial effects of stroke-unit care in stroke patients with atrial fibrillation.
Conclusion: SU care improved the detection of AF and the rate of anticoagulation consideration in acute stroke patients. Our findings support the benefits of continuous cardiac monitoring in the SU for stroke patients. PMID: 23364960 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Choi HY, Seo JH, Yang JH, Kim YD, Jung YH, Cho HJ, Nam HS, Heo JH Tags: Yonsei Med J Source Type: research

Health-Related Quality of Life and Cognitive Functioning at On- and Off-Treatment Periods in Children Aged between 6-13 Years Old with Brain Tumors: A Prospective Longitudinal Study.
Conclusion: The cognitive ability and intelligence level of the patients significantly declined between on and off treatment periods, and higher intelligence functioning at both on and off treatment was correlated with long-term higher HRQOL. Further investigations that monitor intelligence, HRQOL and parenting stress over a longer period, using a greater number of participants, are needed. PMID: 23364961 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: An KJ, Joung YS, Sung KW, Kim JH Tags: Yonsei Med J Source Type: research

Precommissural fornix in the human brain: a diffusion tensor tractography study.
Conclusion: We believe that the methodology and results of this study would be helpful to future research on the precommissural fornix and in the elucidation of the pathology of diseases involving the precommissural fornix. PMID: 23364962 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Yeo SS, Seo JP, Kwon YH, Jang SH Tags: Yonsei Med J Source Type: research

Intrathecal lamotrigine attenuates mechanical allodynia and suppresses microglial and astrocytic activation in a rat model of spinal nerve ligation.
Conclusion: Continuously administered intrathecal lamotrigine blocked the development of mechanical allodynia induced by SNL with suppression of microglial and astrocytic activation. Continuous intrathecal administration of lamotrigine may be a promising therapeutic intervention to prevent neuropathy. PMID: 23364963 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Choi YS, Jun IG, Kim SH, Park JY Tags: Yonsei Med J Source Type: research

Anti-allodynic effects of levodopa in neuropathic rats.
Conclusion: Levodopa reversed tactile, cold and heat allodynia in neuropathic rat without any side effects. PMID: 23364964 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Park HJ, Joo HS, Kim YH, Kwon OK, Lee J, Kim ES, Moon DE Tags: Yonsei Med J Source Type: research

Early differential changes in coronary plaque composition according to plaque stability following statin initiation in acute coronary syndrome: classification and analysis by intravascular ultrasound-virtual histology.
Conclusion: A clear reduction of lipid core was observed only for the TCFA plaque type, suggesting that changes in plaque composition following statin therapy might occur earlier in vulnerable plaque than in stable plaque; the effect may be related to the anti-inflammatory effects of statins. PMID: 23364965 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Hwang DS, Shin ES, Kim SJ, Lee JH, Kim JM, Lee SG Tags: Yonsei Med J Source Type: research

Improvement of glycemic control after re-emphasis of lifestyle modification in type 2 diabetic patients reluctant to additional medication.
Conclusion: In this study, 35.3% of the patients with mild or moderately uncontrolled type 2 diabetes showed the significant improvement of HbA1c levels after 3 months by simply regulating their daily diet and exercise without change of medication. This suggests that the lifestyle modification is significantly associated with the improvement of glucose control. PMID: 23364966 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kim HJ, Jung TS, Jung JH, Kim SK, Lee SM, Kim KY, Kim DR, Seo YM, Hahm JR Tags: Yonsei Med J Source Type: research

Association of Variants in PPARγ², IGF2BP2, and KCNQ1 with a Susceptibility to Gestational Diabetes Mellitus in a Korean Population.
Conclusion: Our results indicated that genetic polymorphisms could also be of value in predicting the occurrence and diagnosis of GDM. PMID: 23364967 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Chon SJ, Kim SY, Cho NR, Min DL, Hwang YJ, Mamura M Tags: Yonsei Med J Source Type: research

Economic burden of high-responding inhibitors in patients with hemophilia a in taiwan.
Conclusion: Our data reveal higher medical expenditures burden for patients with HA and high-responding inhibitors in Taiwan. Future research is encouraged to evaluate the impact of this burden on patient quality of life. PMID: 23364968 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Tu TC, Cheng SN, Chen JD, Cham TM, Chung MI Tags: Yonsei Med J Source Type: research

Risk factors of transfusion in anemia of very low birth weight infants.
Conclusion: Anemia of prematurity was correlated with increased laboratory blood loss, decreased birth weight, prolonged parenteral nutrition, and delayed body weight gain. Accordingly, reducing laboratory phlebotomy loss and parenteral nutrition, as well as improving body weight gain, may be beneficial to infants with anemia of prematurity. PMID: 23364969 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Jeon GW, Sin JB Tags: Yonsei Med J Source Type: research

Blockade of VEGFR-1 and VEGFR-2 Enhances Paclitaxel Sensitivity in Gastric Cancer Cells.
Conclusion: We suggest that blockade of VEGFR-1 and VEGFR-2 enhances paclitaxel sensitivity in TUBB3-expressing gastric cancer cells. PMID: 23364970 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Hwang JE, Lee JH, Park MR, Kim DE, Bae WK, Shim HJ, Cho SH, Chung IJ Tags: Yonsei Med J Source Type: research

The role of one-year endoscopic follow-up for the esophageal remnant and gastric conduit after esophagectomy with gastric reconstruction for esophageal squamous cell carcinoma.
Conclusion: One year after esophagectomy, endoscopic findings were not correlated with clinical symptoms, except those related to stricture. Routine endoscopic follow-up is a useful tool for identifying latent functional and oncological lesions. PMID: 23364971 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Park SY, Lee HS, Jang HJ, Lee JY, Joo J, Zo JI Tags: Yonsei Med J Source Type: research

Contributing factors on lymph node yield after surgery for mid-low rectal cancer.
Conclusion: Preoperative CCRT was an independent risk factor for failure to harvest an appropriate number of lymph nodes, and node-negative patients who received CCRT had fewer lymph nodes harvested. PMID: 23364972 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Ahn YJ, Kwon HY, Park YA, Sohn SK, Lee KY Tags: Yonsei Med J Source Type: research

Diagnostic value and prognostic significance of pleural C-reactive protein in lung cancer patients with malignant pleural effusions.
Conclusion: P-CRP is superior to s-CRP in determining pleural fluid etiology. Quantitative measurement of p-CRP might be a useful complementary diagnostic and prognostic test for lung cancer patients with MPE. PMID: 23364973 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Park DS, Kim D, Hwang KE, Hwang YR, Park C, Seol CH, Cho KH, Kim BR, Park SH, Jeong ET, Kim HR Tags: Yonsei Med J Source Type: research

Endobronchial metastases from extrathoracic malignancy.
Conclusion: EBM develop in various types of malignancies at various times with unremarkable manifestations. Therefore, physicians should consider the possibility of EBM, especially if a patient has a history of any malignancy, regardless of respiratory symptoms. Respiratory symptoms related with EBM can be treated by various safe procedures. PMID: 23364974 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Lee SH, Jung JY, Kim do H, Lee SK, Kim SY, Kim EY, Kang YA, Park MS, Kim YS, Chang J, Kim SK Tags: Yonsei Med J Source Type: research

Significance of neoadjuvant hormonal therapy in radical retropubic prostatectomy: a retrospective single-surgeon study.
Conclusion: The present single-surgeon case series study revealed a trend toward a lower rate of PCa recurrence in NHT+RRP treated patients compared to those treated with RRP alone, but this did not reach statistical significance, despite the fact that NHT+RRP patients exhibited higher serum PSA levels preoperatively. Prospective studies with a longer duration of observation and a greater number of patients would be helpful in evaluating NHT more definitively. PMID: 23364975 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Yamamichi F, Shigemura K, Morishita S, Yamanaka K, Tanaka K, Miyake H, Fujisawa M Tags: Yonsei Med J Source Type: research

Long-term (postnatal day 70) outcome and safety of intratracheal transplantation of human umbilical cord blood-derived mesenchymal stem cells in neonatal hyperoxic lung injury.
Conclusion: The protective and beneficial effects of IT transplantation of hUCB-MSCs in neonatal hyperoxic lung injuries were sustained for a prolonged recovery period without any long-term adverse effects up to P70. PMID: 23364976 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Ahn SY, Chang YS, Kim SY, Sung DK, Kim ES, Rime SY, Yu WJ, Choi SJ, Oh WI, Park WS Tags: Yonsei Med J Source Type: research

External Validation of the Acute Physiology and Chronic Health Evaluation II in Korean Intensive Care Units.
Conclusion: For Koreans, the APACHE II exhibits poor calibration and modest discrimination for hospital mortality. Therefore, a new model is needed to accurately predict mortality in critically ill Korean patients. PMID: 23364977 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kim JY, Lim SY, Jeon K, Koh Y, Lim CM, Koh SO, Na S, Lee KM, Lee BH, Kwon JY, Lee KH, Yoon SH, Park J, Suh GY Tags: Yonsei Med J Source Type: research

Feasibility and early outcomes of intensivist-led critical care after major trauma in the korean ICU.
Conclusion: The intensivist model of critical care is feasible, and there is room for improvement in the care of major trauma patients. Although trauma systems take time to mature, future studies are needed to evaluate the best model of critical care delivery for severely injured patients in Korea. PMID: 23364978 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kim KD, Lee JW, Park HK Tags: Yonsei Med J Source Type: research

Rapamycin Inhibits Transforming Growth Factor β1-Induced Fibrogenesis in Primary Human Lung Fibroblasts.
Conclusion: These results indicate that rapamycin effectively suppresses TGF-β1-induced type III collagen and fibronectin levels in primary human lung fibroblasts partly through the mTOR/p70S6K pathway. Rapamycin has a potential value in the treatment of pulmonary fibrosis. PMID: 23364979 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Gao Y, Xu X, Ding K, Liang Y, Jiang D, Dai H Tags: Yonsei Med J Source Type: research

Interleukin-10 Down-Regulates Cathepsin B Expression in Fetal Rat Alveolar Type II Cells Exposed to Hyperoxia.
Conclusion: Our study suggests that CB is enhanced in an oxygen- concentration-dependent manner, and IL-10 has an inhibitory effect on CB expression in FATIICs during hyperoxia. PMID: 23364980 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Lee HS, Kim CK Tags: Yonsei Med J Source Type: research

Rapid decrease of intact parathyroid hormone could be a predictor of better response to cinacalcet in hemodialysis patients.
Conclusion: Cinacalcet was effective in most hemodialysis patients with refractory SHPT. The presence of an early response was closely associated with the achievement of target levels of iPTH. PMID: 23364981 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kim JK, Kwon YJ, Kim SW, Kim YH, Park CW, Choi KB, Hwang SD, Choi KH Tags: Yonsei Med J Source Type: research

Easily removable ureteral catheters for internal drainage in children: a preliminary report.
Conclusion: Our new method for removing the ureteral catheter would shorten hospital stays and lower levels of anxiety when removing ureteral catheters in patients with a high risk of postoperative ureteral obstruction. PMID: 23364982 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Park KK, Kim MU, Chung MS, Lee DH, Hong CH Tags: Yonsei Med J Source Type: research

Outpatient-Based Pneumococcal Vaccine Campaign and Survey of Perceptions about Pneumococcal Vaccination in Patients and Doctors.
Conclusion: Annual outpatient-based campaigns early in the influenza season may improve pneumococcal vaccine coverage rates. Doctor's advice was the most important encouraging factor for vaccination. PMID: 23364983 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Song JY, Cheong HJ, Heo JY, Noh JY, Seo YB, Kim IS, Choi WS, Kim WJ Tags: Yonsei Med J Source Type: research

Evaluation of a rapid detection influenza virus a antigens kit using paired serum antibody test.
Conclusion: The sensitivity for Influenza A antigen detection by using GICA is relatively low, the specificity is relatively satisfactory. PMID: 23364984 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Chen H, Wang H, Li X, You L, Wei J, Shi W Tags: Yonsei Med J Source Type: research

Causes of Death of Prisoners of War during the Korean War (1950-1953).
Conclusion: The information and data on POWs' deaths during the Korean War reflects the critical impact of the POWs' living conditions and the effect of public health measures implemented in POW camps during the war. PMID: 23364985 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Lee MS, Kang MJ, Huh S Tags: Yonsei Med J Source Type: research

Preventive Effects of Lactobacillus Mixture on Experimental E. coli Urinary Tract Infection in Infant Rats.
Conclusion: The intravesically instilled LM significantly prevented experimental pyelonephritis in infant rats, however, LM administered orally to the pregnant and lactating mother rats did not. PMID: 23364986 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Lee JW, Lee JH, Sung SH, Lee SJ Tags: Yonsei Med J Source Type: research

Expression and Localization of COMMD1 Proteins in Human Placentas from Women with Preeclampsia.
Conclusion: This study demonstrated increased placental COMMD1 expression in women with severe preeclampsia compared to that found in women with normal pregnancies, and this finding might contribute to a better understanding of the pathophysiology of preeclampsia. PMID: 23364987 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kwon HS, Park SH, Hwang HS, Sohn IS, Kim SN Tags: Yonsei Med J Source Type: research

Analysis of single nucleotide polymorphism in adolescent idiopathic scoliosis in Korea: for personalized treatment.
Conclusion: Thus, on the basis of this study, if more SNPs or candidate genes are studied in a larger population in Korea, personalized treatment of Korean AIS patients might become a possibility. PMID: 23364988 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Moon ES, Kim HS, Sharma V, Park JO, Lee HM, Moon SH, Chong HS Tags: Yonsei Med J Source Type: research

Clinical results of auto-iliac cancellous bone grafts combined with implantation of autologous bone marrow cells for osteonecrosis of the femoral head: a minimum 5-year follow-up.
Conclusion: The results of the present study suggested that patients who have a large sized lesion or medium sized laterally located lesion would not be good candidates for the head preserving procedure. However, for medium sized lesions, this procedure generated clinical results comparable to those of other head preserving procedures. PMID: 23364989 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kang JS, Moon KH, Kim BS, Kwon DG, Shin SH, Shin BK, Ryu DJ Tags: Yonsei Med J Source Type: research

Relation among the Gross Motor Function, Manual Performance and Upper Limb Functional Measures in Children with Spastic Cerebral Palsy.
Conclusion: Gross motor function, bimanual performance and the best capacity of each hand are closely related with each other in children with bilateral CP, but not in children with unilateral CP. PMID: 23364990 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Park ES, Rha DW, Park JH, Park DH, Sim EG Tags: Yonsei Med J Source Type: research

Acute Modulations in Stratum Corneum Permeability Barrier Function Affect Claudin Expression and Epidermal Tight Junction Function via Changes of Epidermal Calcium Gradient.
Abstract Tight junction (TJ) is recognized as a second barrier of the skin. Altered expression of TJ proteins in various skin diseases characterized by the abnormal permeability barrier such as psoriasis suggests that TJ could be affected by stratum corneum (SC) barrier status. However, the physiological relationship between SC and TJ barrier remains to be investigated. Therefore, we examined the effect of SC barrier disruption on the expression of TJ proteins, claudin (Cldn)-1 and Cldn-4, and TJ barrier function in hairless mouse skin. We also investigated whether the alterations in epidermal Ca(2+) affected TJ pr...
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Baek JH, Lee SE, Choi KJ, Choi EH, Lee SH Tags: Yonsei Med J Source Type: research

A Case of Long QT Syndrome Type 3 Aggravated by Beta-Blockers and Alleviated by Mexiletine: The Role of Epinephrine Provocation Test.
Abstract Long QT syndrome (LQTs) is an uncommon genetic disease causing sudden cardiac death with Torsade de Pointes (TdP). The first line drug treatment has been known to be β-blocker. We encountered a 15-year-old female student with LQTs who had prolonged QTc and multiple episodes of syncope or agonal respiration during sleep. Although her T wave morphology in surface electrocardiography resembled LQTs type 1, her clinical presentation was unusual. During the epinephrine test, TdP was aggravated during β-blocker medication, but alleviated by sodium channel blocker (mexiletine). Therefore, she underwent implanta...
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Park J, Kim SK, Pak HN Tags: Yonsei Med J Source Type: research

Dorsal-Plantar Loop Technique Using Chronic Total Occlusion Devices via Anterior Tibial Artery.
In this report, however, we describe a case in which dorsal-plantar loop technique with only one antegrade approach, using chronic total occlusion devices via anterior tibial artery, was used to successfully recanalize BTK arteries. We think that this new technique, which may represent a safe and feasible endovascular option to avoid more invasive, time-consuming, and riskier surgical procedures, especially in end-stage renal disease and diabetes, should be considered whenever the foot is at risk, and results of above-the-ankle percutaneous transluminal angioplasty remain unsatisfactory or insufficient to achieve limb salv...
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kim S, Choi D, Shin S, Shin DH, Kim JS, Kim BK, Ko YG, Hong MK, Jang Y Tags: Yonsei Med J Source Type: research

A 47,X,+t(X;X)(p22.3;p22.3)del(X)(p11.23q11.2),Y Klinefelter Variant with Morbid Obesity.
We report the case of a 35-yr-old man with hypogonadism and morbid obesity and diabetes mellitus. He had gynecomastia, small testes and penis, very sparse body hair and his body mass index was 44.85. He did not report experiencing broken voice and was able to have erections. We conducted a chromosome study. His genotype was 47,X,+t(X;X)(p22.3;p22.3)del(X)(p11.23q11.2). In this case, the patient was diagnosed as Klinefelter syndrome. He showed rare phenotypes like morbid obesity and average height and the phenotype may be caused by the karyotype and the excess number of X chromosome. Further studies of the relationship betw...
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Kim Y, Kim WJ, Huh JH, Lee S, Kim D, Hong JW, Lee EJ Tags: Yonsei Med J Source Type: research

Can we accurately assess liver fibrosis with fibroscan® using fewer valid measurements?
PMID: 23364995 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Authors: Pournik O, Alavian SM, Eslami S Tags: Yonsei Med J Source Type: research

Erratum to "Prevalence, Incidence, and Factor Concentrate Usage Trends of Hemophiliacs in Taiwan" by Tu TC, et al.(Yonsei Med J 2013;54:71-80.).
Authors: PMID: 23364996 [PubMed - in process]
Source: Yonsei Medical Journal - February 3, 2013 Category: Universities & Medical Training Tags: Yonsei Med J Source Type: research

Cloning and characterization of two Argonaute genes in wheat (Triticum aestivum L.)
Conclusions: Two putative wheat Argonaute genes, TaAGO1b and TaAGO4, were cloned. Phylogenetic analysis, prediction of conserved domains and catalytic motifs, and modelling of their protein structures suggested that they encode functional Argonaute proteins. Temporal and spatial expression analyses indicated that these genes are potentially involved in developmental regulation of wheat plants.
Source: BioMed Central - February 3, 2013 Category: Journals (General) Authors: Fanrong MengHaiying JiaNa LingYinlei XueHao LiuKetao WangJun YinYongchun Li Source Type: research