Urology & Nephrology This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the most recent publications within this specialty of the MedWorm directory.

Back pain medication link to erectile dysfunction
Results of a large US study show that men who are prescribed opioids for back pain are significantly more likely to require medications for erectile dysfunction and testosterone depletion than those who have not taken the drugs. (Source: MedWire News - Urology)
Source: MedWire News - Urology - May 20, 2013 Category: Urology & Nephrology Source Type: news

Immunohistochemical Expression of ERG in the Molecular Epidemiology of Fatal Prostate Cancer Study
CONCLUSIONSOur results demonstrate that ERG protein expression is readily quantifiable with an existing commercial antibody. Evaluating ERG protein expression may improve our ability to identify the subset of more aggressive, invasive prostate cancers. Prostate 9999: XX–XX, 2013. © 2013 Wiley Periodicals, Inc. (Source: The Prostate)
Source: The Prostate - May 20, 2013 Category: Urology & Nephrology Authors: Sheila Weinmann, Stephen K. Van Den Eeden, Reina Haque, Chuhe Chen, Kathryn Richert‐Boe, Jacob Schwartzman, Lina Gao, Deborah L. Berry, Bhaskar V. S. Kallakury, Joshi J. Alumkal Tags: Original Article Source Type: research

Understanding Hypernatremia
The case report and discussion of Al-Absi et al is of interest for demonstrating the development of hypernatremia in one patient in the presence of volume overload and with volume depletion. However, some points in the discussion may be considered. (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Thomas Kahn Tags: Letters to the Editor Source Type: research

Thiazides for Hypervolemic Hypernatremia: A Valid Therapeutic Strategy?
I congratulate Al-Absi et al on an excellent review of the concepts and management of hypernatremia. As the authors point out, when hypervolemic hyponatremia is encountered, sodium-rich urine must be diuresed in an attempt to induce a negative sodium balance in excess of the negative water balance to bring down plasma sodium level and subsequently total-body volume. Could this goal not be achieved better with thiazide-group diuretics, either alone or alternating with loop diuretics? By promoting proximal water reabsorption and upregulating distal aquaporin 2 channels, thiazides might help avoid the need to give simultaneou...
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Madhav C. Menon Tags: Letters to the Editor Source Type: research

In Reply to ‘Understanding Hypernatremia’ and ‘Thiazides for Hypervolemic Hypernatremia: A Valid Therapeutic Strategy?’
In reply to Dr Kahn, hypervolemic hypernatremia requires disproportionate elevations of total-body sodium content relative to total-body water. Because sodium is largely restricted to the extracellular compartment, water achieves osmotic equilibrium by moving from intracellular to extracellular space. The net result is that the extracellular space expands, total-body water is elevated, and intracellular fluid volume is decreased. These changes are most likely to occur in skeletal muscle, which has limited acute cell volume regulatory mechanisms compared with brain cells. Dr Kahn raises an important observation that in sust...
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Barry M. Wall, Elvira O. Gosmanova Tags: Letters to the Editor Source Type: research

Relationship Between Retinopathy and Cognitive Impairment May Be Confounded by Visual Impairment
In the article “Retinopathy and Cognitive Impairment in Adults With CKD” by Yaffe et al, the authors report that participants with retinopathy had an increased likelihood of cognitive impairment on executive function, attention, and naming assessments after multivariable adjustment. We commend the authors on exploring this important topic. However, we question whether the results may be confounded by concurrent changes in lens opacity, visual acuity, or contrast sensitivity in individuals with retinopathy. The 3 cognitive assessments that elicited significant differences between the 2 groups, the Trails A (attention), ...
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Janine Farragher, Sarbjit Vanita Jassal Tags: Letters to the Editor Source Type: research

Single-Side Renal Sympathetic Denervation in a Hypertensive Patient With a Single Kidney
We report what to our knowledge is the first renal sympathetic denervation procedure in a patient with only one kidney who had resistant arterial hypertension, diabetes mellitus, and chronic kidney disease. The patient was a 69-year-old man whose recurrent hypertensive crises could not be controlled by treatment with 6 drugs of different classes and who had recently experienced a transient ischemic attack. Denervation was considered as a “bail-out” therapeutic option. Given that he had only one kidney, the patient's case was discussed by an interdisciplinary cardiology and nephrology team. (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Oliver Dörr, Christian Hamm, Holger M. Nef Tags: Letters to the Editor Source Type: research

Masthead
(Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Source Type: research

Editorial Board
(Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Source Type: research

Contents
(Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Source Type: research

July Highlights
(Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Source Type: research

Abbreviated Information for Authors
(Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Source Type: research

Announcements
(Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Source Type: research

This Month in AJKD
See Olden et al, pages 889-898; and Rao, pages 851-854. Cardiovascular disease (CVD) is the major complication of CKD, and most people with kidney disease die of CVD before kidney failure; however, the mechanisms of excess cardiovascular risk in CKD patients are not fully understood. In this month's AJKD, Olden et al test the hypothesis that genetic kidney variants might increase the risk of vascular disease and that these vascular variants might be associated with kidney disease traits. The authors report that while they confirmed one locus (SH2B3) as associated with both kidney and cardiovascular disease, the primary fi...
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Source Type: research

Quiz Page JUNE 2013: Graft Dysfunction After Kidney Transplantation in an Adolescent
A 15-year-old boy with no relevant medical or family history presented with nausea and fatigue. His blood pressure was 150/90 mm Hg, but the rest of the physical examination findings were normal. Laboratory investigations showed the following values: serum creatinine, 18.9 mg/dL (estimated glomerular filtration rate [GFR], 5 mL/min/1.73 m2 by the modified Schwartz formula); serum urea nitrogen, 549 mg/dL; parathyroid hormone, 496 (reference range, 9-55) pg/mL; and hemoglobin, 9.0 g/dL. Urinalysis showed hematuria (1+) and proteinuria (protein excretion, 930 mg/24 h), with occasional red blood cells on sediment evaluation. ...
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Badria Al Ghaithi, Siew-Le Chong, Reham Al Mardini, Seetha Radhakrishnan, Rohan John, Lisa A. Robinson Source Type: research

α-Klotho and Kidney Function Decline: An Important Step Forward in Understanding the Link Between Mineral Metabolism and Kidney Disease Progression
Related Article, p. 899 (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Orlando M. Gutiérrez, Joachim H. Ix Tags: Editorials Source Type: research

Dialysis Bundling and Small Dialysis Organizations: A Call for Close Monitoring
Related Article, p. 947 (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Yelena Slinin, Areef Ishani Tags: Editorials Source Type: research

Bioimpedance Technology and Optimal Fluid Management
Related Article, p. 957 (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: John T. Daugirdas Tags: Editorials Source Type: research

Hurricane Sandy as a Kidney Failure Disaster
A kidney failure disaster can be defined as an event that places large numbers of patients treated with maintenance dialysis or individuals with a recent onset of acute kidney injury (AKI) at risk due to lack of access to dialysis care (). (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Kenneth D. Lempert, Jeffrey B. Kopp Tags: Editorials Source Type: research

Cardiovascular and Kidney Disease Traits—Pleiotropic or Just Polygenic?
Related Article, p. 889 (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - May 20, 2013 Category: Urology & Nephrology Authors: Madhumathi Rao Tags: Editorials Source Type: research

Men and women, so different, so similar: observations from cross‐sex hormone treatment of transsexual subjects
Summary Sexual differentiation in mammals is largely driven by the presence of androgen in males and their absence in females. The presence of androgens induces a number of irreversible changes in males: prenatally, the genital differentiation; during puberty, the development of secondary sex characteristics – the larger facial bones, hand, feet and height in males. A large number of metabolic variables are influenced by sex hormones and consequently show difference between men and women, and this helps to explain differences in pathologies, such as cardiovascular disease, bone fractures and auto immune disease. There is...
Source: Andrologia - May 20, 2013 Category: Urology & Nephrology Authors: L. J. Gooren, E. J. Giltay Tags: Short Communication Source Type: research

Snapshot of Transurethral resection of bladder tumours in the United Kingdom Audit (STUKA)
ConclusionThe quality of TURBT in the UK is high. Areas for improvement include the timeliness of diagnosis and treatment, and improved care of patients with intermediate risk NMIBC and MIBC. The snapshot methodology is promising but widening participation is a priority. (Source: BJU International)
Source: BJU International - May 20, 2013 Category: Urology & Nephrology Authors: Christine Gan, Amit Patel, Sarah Fowler, James Catto, Derek Rosario, Timothy O′Brien Tags: Original Article Source Type: research

IMRT Benefits in Prostate Cancer Questioned (CME/CE)
(MedPage Today) -- Men with prostate cancer gained no obvious benefits from treatment with intensity-modulated radiation therapy (IMRT) as compared with an older, less expensive technique, an analysis of a government database suggests. (Source: MedPage Today Urology)
Source: MedPage Today Urology - May 20, 2013 Category: Urology & Nephrology Source Type: news

No Single Reason for Readmission After GI Surgery (CME/CE)
ORLANDO (MedPage Today) -- A number of patient, surgical, and postoperative factors were associated with 30-day hospital readmission following major gastrointestinal resection, and some may be preventable, researchers reported here. (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - May 20, 2013 Category: Urology & Nephrology Source Type: news

No-treatment approach may be best choice for older prostate cancer patients
Older prostate cancer patients with other underlying health conditions should think twice before committing to surgery or radiation therapy for their cancer, according to a multi-center study led by researchers from the UCLA Department of Urology. The study reports 14-year survival outcomes for 3,000 men diagnosed with prostate cancer between 1994 and 1995. The results suggest that older patients with low- or intermediate-risk prostate cancer who have at least three underlying health problems, or comorbidities, are much more likely to die of something other than their cancer. "For men with low-to-intermediate...
Source: UCLA Newsroom: Health Sciences - May 20, 2013 Category: Universities & Medical Training Source Type: news

Add Olive Oil or Nuts to Guard Brain (CME/CE)
(MedPage Today) -- A Mediterranean diet heavy on extra-virgin olive oil or nuts does more to keep the aging brain agile than simply switching to a low-fat diet, researchers found. (Source: MedPage Today Nephrology)
Source: MedPage Today Nephrology - May 20, 2013 Category: Urology & Nephrology Source Type: news

Sterilized Honey Combats Infections in Dialysis CathetersSterilized Honey Combats Infections in Dialysis Catheters
Honey was as effective as mupirocin in preventing infections in most patients, researchers report. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - May 20, 2013 Category: Consumer Health News Tags: Nephrology News Source Type: news