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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Combined Cisplatin-Based Chemoembolization and Radiation Therapy for Hepatocellular Carcinoma Invading the Main Portal Vein
Conclusions Chemoembolization combined with RT improves survival, with a median survival of 12 months in patients with HCC with main PV involvement. (Source: Journal of Vascular and Interventional Radiology)
Source: Journal of Vascular and Interventional Radiology - June 26, 2015 Category: Radiology Source Type: research

Circulating resistin levels are early and significantly increased in deceased brain dead organ donors, correlate with inflammatory cytokine response and remain unaffected by steroid treatment
IntroductionResistin is a pro-inflammatory adipokine that increases after brain injury (trauma, bleeding) and may initiate an inflammatory response. Resistin was found increased in deceased, brain dead organ donors (DBD) and correlated with delayed graft function after kidney transplantation. The kinetics of resistin during brain death (BD), its impact on the inflammatory response and the influence of several donor variables on resistin levels are still unknown. Methods: Resistin along with a panel of Th1/Th2 cytokines [interferon (IFN)-gamma, interleukin (IL)-1beta, IL-2, IL-6, IL-8, IL10, IL-12, IL-13 and tumor necrosis ...
Source: Journal of Translational Medicine - June 26, 2015 Category: Research Authors: Rille PulleritsSimona OlteanAnne FlodénMihai Oltean Source Type: research

Electrochemotherapy as a new approach on pancreatic cancer and on liver metastases
Electrochemotherapy is a local non-thermal treatment for cancer ablation. Currently, many studies and case report have investigated the differences in effectiveness of electrochemotherapy with respect to tumor type, chemotherapeutic drug, and route of drug administration. ESOPE trial validated standard operating procedures [SOP] for ECT using the Cliniporator device and demonstrated that ECT is a simple, highly efficacious, and cost-effective treatment of cutaneous and subcutaneous nodules from different primary tumors for cutaneous or superficial lesions. (Source: International Journal of Surgery)
Source: International Journal of Surgery - June 26, 2015 Category: Surgery Authors: Tafuto Salvatore, von Arx Claudia, De Divitiis Chiara, Tracey Maura Claire, Palaia Raffaele, Albino Vittorio, Fusco Roberta, Membrini Massimo, Petrillo Antonella, Granata Vincenza, Izzo Francesco, ENETS Center of Excellence Multidisciplinary Group for Neu Tags: Original Research Source Type: research

Vitamin D Status in Children with Chronic Kidney Disease
(National Institute of Child Health, Karachi, Pakistan)(Original Article; p94-98) (Source: Journal of Pakistan Medical Students)
Source: Journal of Pakistan Medical Students - June 26, 2015 Category: Universities & Medical Training Authors: JPMS Source Type: research

Wound dehiscence in a sample of 1,776 cystectomies – identification of predictors and implications for outcomes
ConclusionsOur study is the first to identify predictors of wound dehiscence following radical cystectomy in a large, contemporary multi‐institutional cohort. Identifying patients at risk for postoperative wound complications may guide the use preventative measures at the time of surgery.This article is protected by copyright. All rights reserved. (Source: BJU International)
Source: BJU International - June 26, 2015 Category: Urology & Nephrology Authors: Christian P. Meyer, Arturo J. Rios Diaz, Deepansh Dalela, Julian Hanske, Daniel Pucheril, Marianne Schmid, Vincent Q. Trinh, Jesse D. Sammon, Mani Menon, Felix K.H. Chun, Joachim Noldus, Margit Fisch, Quoc‐Dien Trinh Tags: Original Article Source Type: research

Association between number of prostate biopsies and patient‐reported functional outcomes after radical prostatectomy: implications for active surveillance protocols
ConclusionsWe did not find evidence that more preoperative prostate biopsies adversely affected erectile or urinary function at 12 months following RP. This article is protected by copyright. All rights reserved. (Source: BJU International)
Source: BJU International - June 26, 2015 Category: Urology & Nephrology Authors: Christopher B. Anderson, Amy L. Tin, Daniel D. Sjoberg, John P. Mulhall, Jaspreet Sandhu, Karim Touijer, Vincent P. Laudone, James A. Eastham, Peter T. Scardino, Behfar Ehdaie Tags: Original Article Source Type: research

Dental Health and Mortality in People With End-Stage Kidney Disease Treated With Hemodialysis: A Multinational Cohort Study
Conclusions In adults treated with hemodialysis, poorer dental health was associated with early death, whereas preventive dental health practices were associated with longer survival. (Source: American Journal of Kidney Diseases)
Source: American Journal of Kidney Diseases - June 26, 2015 Category: Urology & Nephrology Source Type: research

This Month in Pediatric Urology
(Source: The Journal of Urology)
Source: The Journal of Urology - June 26, 2015 Category: Urology & Nephrology Authors: Michael L. Ritchey Source Type: research

This Month in Adult Urology
(Source: The Journal of Urology)
Source: The Journal of Urology - June 26, 2015 Category: Urology & Nephrology Authors: Joseph A. Smith Source Type: research

Robot assisted ureteral reconstruction using buccal mucosa
To describe the technique of robotic buccal mucosa graft ureteroplasty as a minimally invasive alternative method of ureteral reconstruction for proximal or multifocal ureteral strictures not amenable to primary anastomosis. (Source: Urology)
Source: Urology - June 26, 2015 Category: Urology & Nephrology Authors: Lee C. Zhao, Yuka Yamaguchi, Darren J. Bryk, Sarah A. Adelstein, Michael D. Stifelman Source Type: research

Urological Surveillance and Medical Complications After Spinal Cord Injury in the United States
To evaluate national patterns of urologic follow up after SCI and the occurrence and predictors of urological complications. (Source: Urology)
Source: Urology - June 26, 2015 Category: Urology & Nephrology Authors: Anne P. Cameron, Julie Lai, Christopher S. Saigal, J Quentin Clemens, NIDDK Urological Diseases in America Project Source Type: research

Trends in prostate specific antigen screening, prostate biopsies, urology visits and prostate cancer treatments from 2000 to 2012
To determine whether the rates of PSA screening, related biopsies, and subsequent prostate cancer utilization decreased between 2000 and 2012 in a large, managed care organization. (Source: Urology)
Source: Urology - June 26, 2015 Category: Urology & Nephrology Authors: Lauren P. Wallner, Jin-Wen Y. Hsu, Ronald K. Loo, Darryl E. Palmer-Toy, Joanne E. Schottinger, Steven J. Jacobsen Source Type: research

Contrast-Enhanced Ultrasound for Surveillance of Radiofrequency-Ablated Renal Tumors: A Prospective, Radiologist-blinded Pilot Study
To prospectively evaluate the performance of contrast-enhanced ultrasound (CEUS) for surveillance after radiofrequency ablation (RFA) of small renal masses (SRM) by comparing CEUS to the contrast-enhanced computed tomography (CECT), current gold standard. (Source: Urology)
Source: Urology - June 26, 2015 Category: Urology & Nephrology Authors: Christopher B. Allard, Alexander Coret, Shawn Dason, Camilla Tajzler, Bobby Shayegan, Edward D. Matsumoto, Anil Kapoor Source Type: research

A two-day bladder diary for children: is it enough?
A bladder diary (BD) is a simple and non-invasive method of evaluating people with lower urinary tract symptoms (LUTS). Recently, the ICCS recommended a 48-hour daytime frequency and volume chart (which does not need to be recorded on 2 consecutive days) to evaluate lower urinary tract (LUT) dysfunction. However, some studies on adults have demonstrated that a minimum of 3 days is required. It is believed that, to date, there are no studies in the literature that compare a 2-day BD with a 3-day BD. (Source: Journal of Pediatric Urology)
Source: Journal of Pediatric Urology - June 26, 2015 Category: Urology & Nephrology Authors: I. Lopes, M.L. Veiga, A.A. Nascimento, C.A. Brasil, A. Hoffmann, U. Barroso Source Type: research

Current surgical standards of care in Wilms tumor
Wilms tumor (WT) is the second most common abdominal tumor in children. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - June 26, 2015 Category: Urology & Nephrology Authors: Kathleen Kieran, Peter F. Ehrlich Tags: Seminar article Source Type: research

Neoadjuvant chemotherapy administration and time to cystectomy for muscle-invasive bladder cancer: An evaluation of transitions between academic and community settings
This study examines if administration of NAC in the community is associated with differences in type of NAC received, pathologic response rate (pT0), and time to cystectomy as compared to NAC administered at an AMC. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - June 26, 2015 Category: Urology & Nephrology Authors: Tracy L. Rose, Allison M. Deal, Ethan Basch, Paul A. Godley, W. Kimryn Rathmell, William Y. Kim, Young E. Whang, Mary W. Dunn, Andrew Wang, Ronald C. Chen, Matthew E. Nielsen, Raj S. Pruthi, Eric M. Wallen, Michael E. Woods, Angela B. Smith, Matthew I. Mi Tags: Original article Source Type: research

Assessing the clinical benefit of a nomogram to predict specimen-confined disease at radical prostatectomy in patients with high-risk prostate cancer: An external validation
The objective of the current study was to test generalizability and clinical value of a recently published nomogram to predict specimen-confined disease (SCD, pT2-pT3a+R0+pN0) at radical prostatectomy (RP) in patients with clinical high-risk prostate cancer (HRPCa). The nomogram allows improved decision making with curative intent within this heterogeneous patient cohort, which is important, as RP in patients with clinical HRPCa remains a topic of controversy. (Source: Urologic Oncology: Seminars and Original Investigations)
Source: Urologic Oncology: Seminars and Original Investigations - June 26, 2015 Category: Urology & Nephrology Authors: Jens Hansen, Andreas Becker, Luis A. Kluth, Michael Rink, Thomas Steuber, Mario Zacharias, Alberto Briganti, Margit Fisch, Markus Graefen, Felix K.-H. Chun Tags: Original article Source Type: research

Metastasis‐associated in colon cancer 1 is an independent prognostic biomarker for survival in klatskin tumor patients
Conclusion: Our study identified MACC1 as a highly prognostic biomarker for OS and DFS in Klatskin tumor patients. MACC1 expression could become an important diagnostic tool and might be a candidate for targeted therapy. (Hepatology 2015) (Source: Hepatology)
Source: Hepatology - June 26, 2015 Category: Internal Medicine Authors: Andri Lederer, Pia Herrmann, Daniel Seehofer, Manfred Dietel, Johann Pratschke, Peter Schlag, Ulrike Stein Tags: Hepatobiliary Malignancies Source Type: research

Recalibration of Blood Analytes over 25 Years in the Atherosclerosis Risk in Communities Study: Impact of Recalibration on Chronic Kidney Disease Prevalence and Incidence [Informatics and Statistics]
CONCLUSIONS: Analytes remeasured in samples stored for approximately 25 years were highly correlated with original values, but 2 of the 8 analytes showed substantial bias at multiple visits. Laboratory recalibration improved reproducibility of test results across visits and resulted in substantial differences in CKD prevalence. We demonstrate the importance of consistent recalibration of laboratory assays in a cohort study. (Source: Clinical Chemistry)
Source: Clinical Chemistry - June 26, 2015 Category: Chemistry Authors: Parrinello, C. M., Grams, M. E., Couper, D., Ballantyne, C. M., Hoogeveen, R. C., Eckfeldt, J. H., Selvin, E., Coresh, J. Tags: Informatics and Statistics Source Type: research

Tandem Mass Spectrometric Determination of Atypical 3{beta}-Hydroxy-{Delta}5-Bile Acids in Patients with 3{beta}-Hydroxy-{Delta}5-C27-Steroid Oxidoreductase Deficiency: Application to Diagnosis and Monitoring of Bile Acid Therapeutic Response [Pediatric Clinical Chemistry]
CONCLUSIONS: The tandem mass spectrometry method described here for the measurement of 3β-hydroxy-5-bile acid sulfates in urine can be applied to the diagnosis and accurate monitoring of responses to primary bile acid therapy in HSD3B7 patients. (Source: Clinical Chemistry)
Source: Clinical Chemistry - June 26, 2015 Category: Chemistry Authors: Zhang, W., Jha, P., Wolfe, B., Gioiello, A., Pellicciari, R., Wang, J., Heubi, J., Setchell, K. D. R. Tags: Pediatric Clinical Chemistry Source Type: research

Aryltetralols from Holostylis reniformis and syntheses of lignan analogous
Publication date: September 2015 Source:Phytochemistry Letters, Volume 13 Author(s): Marcos D.P. Pereira , Matheus R. Ferreira , Gisele B. Messiano , Isabela Penna Cerávolo , Lucia M.X. Lopes , Antoniana U. Krettli Two new lignans, an aryltetralol and its methyl ether analogous, were isolated from Holostylis reniformis (Aristolochiaceae) together with futokadsurin C and (−)-8′-epi-aristoligone. The latter was also obtained as an enantiomeric mixture by synthesis and was transformed into aryltetralols and aryltetralenes that were subjected to chiral-HPLC separations. The compound structures were determined by spectro...
Source: Phytochemistry Letters - June 26, 2015 Category: Chemistry Source Type: research

Experimental and Finite Element analysis for Prediction of Kidney Injury under blunt impact
Kidneys are third most injured organs in abdominal trauma after liver and spleen, this study therefore is an attempt to understand behaviour of kidneys under blunt trauma. Dynamic impact tests were performed on 20 fresh porcine kidneys to study the injury propagation in the organ, and the acceleration of the impactor was measured. A kidney model was developed with structural details like capsule and cortex. The kidney cortex was modelled with solid hexahedral elements and the capsule was modelled with quadratic shell elements. (Source: Journal of Biomechanics)
Source: Journal of Biomechanics - June 26, 2015 Category: Biomedical Science Authors: Sagar Umale, Caroline Deck, Nicolas Bourdet, Michele Diana, Luc Soler, Remy Willinger Source Type: research

Is Strain Elastography (IO-SE) Sufficient for Characterization of Liver Lesions before Surgical Resection—Or Is Contrast Enhanced Ultrasound (CEUS) Necessary?
Conclusion IO-CEUS is useful for localization and characterization of liver lesions prior to surgical resection whereas IO-SE provided correct characterization only for a limited number of lesions. (Source: PLoS One)
Source: PLoS One - June 26, 2015 Category: Biomedical Science Authors: Ernst Michael Jung et al. Source Type: research

Change in the wheelhouse
(Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Paul Martin Tags: Welcome From The Editor Source Type: research

Delisting of liver transplant candidates because of bacterial sepsis
(Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Andrés Cárdenas, Thierry Gustot Tags: Editorial Source Type: research

Cardiovascular diseases after liver transplantation—a still emerging and unsolved problem!
(Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Ivo W. Graziadei, Andrés Cárdenas Tags: Editorial Source Type: research

The impact of pretransplant hepatic encephalopathy on survival following liver transplantation
In conclusion, grade 3‐4 HE at the time of LT is associated with lower post‐LT survival, with a proposed direct or indirect association of more severe HE before LT with increased rates of post‐LT infections. Increased awareness and vigilance toward treating HE before LT and more aggressive monitoring and treatment for infections in the perioperative setting may improve LT outcomes. Liver Transpl 21:873‐880, 2015. © 2015 AASLD. (Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Robert J. Wong, Maria Aguilar, Robert G. Gish, Ramsey Cheung, Aijaz Ahmed Tags: Original Article Source Type: research

High risk of delisting or death in liver transplant candidates following infections: Results from the North American consortium for the study of end‐stage liver disease
Because Model for End‐Stage Liver Disease (MELD) scores at the time of liver transplantation (LT) increase nationwide, patients are at an increased risk for delisting by becoming too sick or dying while awaiting transplantation. We quantified the risk and defined the predictors of delisting or death in patients with cirrhosis hospitalized with an infection. North American Consortium for the Study of End‐Stage Liver Disease (NACSELD) is a 15‐center consortium of tertiary‐care hepatology centers that prospectively enroll and collect data on infected patients with cirrhosis. Of the 413 patients evaluated, 136 were lis...
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: K. Rajender Reddy, Jacqueline G. O'Leary, Patrick S. Kamath, Michael B. Fallon, Scott W. Biggins, Florence Wong, Heather M. Patton, Guadalupe Garcia‐Tsao, Ram M. Subramanian, Leroy R. Thacker, Jasmohan S. Bajaj, Tags: Original Article Source Type: research

Cardiovascular disease after liver transplantation: When, What, and Who Is at Risk
The evolution of metabolic and cardiovascular disease (CVD) complications after liver transplantation (LT) is poorly characterized. We aim to illustrate the prevalence of obesity and metabolic syndrome (MS), define the cumulative incidence of CVD, and characterize risk factors associated with these comorbidities after LT. A retrospective review of 455 consecutive LT recipients from 1999 to 2004 with an 8‐ to 12‐year follow‐up was performed. Obesity increased from 23.8% (4 months) to 40.8% (3 years) after LT. Increase in body mass index predicted MS at 1 year after LT (odds ratio, 1.1; P < 0.001, per point). CVD de...
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Lynn A. Fussner, Julie K. Heimbach, Chun Fan, Ross Dierkhising, Elizabeth Coss, Michael D. Leise, Kymberly D. Watt Tags: Original Article Source Type: research

Presentation, diagnosis, and management of early hepatic venous outflow complications in whole cadaveric liver transplant
In conclusion, early HVOO is rare, and there is no evidence from this study that a given implantation technique is at a higher risk of developing HVOO (2 HV with extension versus 3 HV and caval replacement; P = 0.11). However, early revisional surgery for HVOO can preserve graft function with retransplantation being reserved for when surgical cavoplasty or radiological stenting is technically not possible. Liver Transpl 21:914‐921, 2015. © 2015 AASLD. (Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Shirin Elizabeth Khorsandi, Anuja Athale, Hector Vilca‐Melendez, Wayel Jassem, Andreas Prachalias, Parthi Srinivasan, Mohamed Rela, Nigel Heaton Tags: Original Article Source Type: research

The travails of setting up a living donor liver transplant program: Experience from Pakistan and lessons learned
The objective of this study was to report outcomes of 100 LDLT recipients in a developing country and to highlight the challenges encountered by a new LDLT program in a resource‐limited setting. We retrospectively reviewed recipients who underwent LDLT between April 2012 and August 2014. Demographics, etiology, graft characteristics, and operative variables were assessed. Outcome was assessed on the basis of morbidity and mortality. All complications of ≥ 3 on the Clavien‐Dindo grading system were included as morbidity. Estimated 1‐year survival was calculated using Kaplan‐Meier curves, and a Log‐rank test wa...
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Faisal Saud Dar, Abu Bakar Hafeez Bhatti, Abdul‐Wahab Dogar, Haseeb Zia, Sadaf Amin, Atif Rana, Rashid Nazer, Nasir Ayub Khan, Etizaz‐ud‐din Khan, Muhammad Zameer Rajput, Muhammad Salih, Najmul Hassan Shah Tags: Original Article Source Type: research

Perioperative changes in nutritional parameters and impact of graft size in patients undergoing adult living donor liver transplantation
(Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Mehmet Agilli, Tolga Dogan Tags: Letter to the Editor Source Type: research

Reply
(Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Toshimi Kaido, Ahmed Hammad, Shinji Uemoto Tags: Letter to the Editor Source Type: research

Impact of multiple transarterial chemoembolization treatments on hepatocellular carcinoma patients awaiting liver transplantation
(Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Tim Cross, Adli Metussin Tags: Letter to the Editor Source Type: research

Reply
(Source: Liver Transplantation)
Source: Liver Transplantation - June 26, 2015 Category: Transplant Surgery Authors: Julie Heimbach, Eleonora Terzi Tags: Letters to the Editor Source Type: research

Role of chemokine pathways in hepatobiliary cancer
• Chemokines, chemoattractant cytokines, and their corresponding receptors regulate critical aspects in the pathogenesis of hepatobiliary cancer• Chemokines are up-regulated in chronic liver diseases, thereby modulating the hepatic microenvironment towards a pro-inflammatory, pro-fibrotic, pro-angiogenic and thus pre-neoplastic milieu• Liver neoplasms provoke pro- and anti-tumor immune responses that are also critically regulated through differential activation of chemokine pathways• Malignant hepatocytes and cholangiocytes respond to distinct chemokine signals, which influence their proliferation and invasiveness...
Source: Cancer Letters - June 26, 2015 Category: Cancer & Oncology Authors: Josef Ehling, Frank Tacke Tags: Mini-review Source Type: research

Simultaneous pharmacokinetics evaluation of human cytochrome P450 probes, caffeine, warfarin, omeprazole, metoprolol and midazolam, in common marmosets (Callithrix jacchus).
Abstract 1. Pharmacokinetics of human cytochrome P450 probes (caffeine, racemic warfarin, omeprazole, metoprolol and midazolam) composite, after single intravenous and oral administrations at doses of 0.20 and 1.0 mg kg(-1), respectively, to four male common marmosets were investigated. 2. The plasma concentrations of caffeine and warfarin decreased slowly in a monophasic manner but those of omeprazole, metoprolol and midazolam decreased extensively after intravenous and oral administrations, in a manner that approximated those as reported for pharmacokinetics in humans. 3. Bioavailabilities were ∼100% ...
Source: Xenobiotica - June 26, 2015 Category: Research Authors: Uehara S, Inoue T, Utoh M, Toda A, Shimizu M, Uno Y, Sasaki E, Yamazaki H Tags: Xenobiotica Source Type: research

Living Donor Kidney Transplantation: Improving Education Outside of Transplant Centers about Live Donor Transplantation-Recommendations from a Consensus Conference.
Discussion of the effect and potential for implementation around each recommendation is featured, particularly regarding reducing racial and socioeconomic disparities in access to LDKT. To accomplish these recommendations, the entire community of professionals and organizations serving kidney patients must work collaboratively toward ensuring accurate, comprehensive, and up-to-date LDKT education for all patients, thereby reducing barriers to LDKT access and increasing LDKT rates. PMID: 26116651 [PubMed - as supplied by publisher] (Source: Clinical Journal of the American Society of Nephrology : CJASN)
Source: Clinical Journal of the American Society of Nephrology : CJASN - June 26, 2015 Category: Urology & Nephrology Authors: Waterman AD, Morgievich M, Cohen DJ, Butt Z, Chakkera HA, Lindower C, Hays RE, Hiller JM, Lentine KL, Matas AJ, Poggio ED, Rees MA, Rodrigue JR, LaPointe Rudow D Tags: Clin J Am Soc Nephrol Source Type: research