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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Utility of renal biopsy in the clinical management of renal disease
This provocative article describes underutilization of kidney biopsies in the diagnosis and prognosis of renal disease.  The authors state that kidney biopsies can aid in the better management of patients with renal disease at all stages. : Atypical Hemolytic–Uremic Syndrome Expert guidelines for the management of alport syndrome and thin basement membrane nephropathy. Indications for renal revascularization—the landscape after the ASTRAL study (Source: Nephrology Now)
Source: Nephrology Now - December 17, 2014 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Nephrology General Nephrology Glomerulonephritis Source Type: research

An approach to cystic kidney diseases: the clinician’s view
This is a nice review on the clinical classification of cystic kidney diseases while new techniques are, including next-generation sequencing, are still under investigation.     : Genetic Investigations of Kidney Disease Perioperative acute kidney injury: risk factors, recognition, management, and outcomes Proximal renal tubular acidosis: a not so rare disorder of multiple etiologies (Source: Nephrology Now)
Source: Nephrology Now - December 17, 2014 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Chronic Kidney Disease Clinical Nephrology General Nephrology Source Type: research

Survival advantage of lanthanum carbonate for hemodialysis patients with uncontrolled hyperphosphatemia
This retrospective study of maintenance hemodialysis patients showed that treatment with lanthanum was independently associated with a reduction in all cause mortality in those patients with uncontrolled hyperphosphatemia. : Usual versus tight control of systolic blood pressure in non-diabetic patients with hypertension (Cardio-Sis): an open-label randomised trial. Survival in daily home hemodialysis and matched thrice-weekly in-center hemodialysis patients. Chronic kidney disease and dipstick proteinuria are risk factors for stent thrombosis in patients with myocardial infarction (Source: Nephrology Now)
Source: Nephrology Now - December 17, 2014 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Clinical Trial Results Fluid & Electrolytes General Nephrology Hemodialysis Source Type: research

The Impact of Timing of Dialysis Initiation on Mortality in Patients with Peritoneal Dialysis
A Korean cohort of 495 incident PD patients were analyzed with respect to the impact of timing of dialysis initiation on mortality.  The authors found that an eGFR < 5 mL/min/1.73m(2) at the initiation of PD was a significant risk factor for death, while an eGFR >10 mL/min/1.73m(2) at the initiation of PD was not associated with improved survival compared with an eGFR of 5 – 10 mL/min/1.73m(2) at the initiation of PD. : Similar Outcomes With Hemodialysis and Peritoneal Dialysis in Patients With End-Stage Renal Disease Canadian Society of Nephrology 2014 clinical practice guideline for timing the initiation of...
Source: Nephrology Now - December 17, 2014 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Chronic Kidney Disease General Nephrology Peritoneal Dialysis Source Type: research

Not just for the holidays, mistletoe could fight obesity-related liver disease
Mistletoe hanging in doorways announces that the holidays are just around the corner. For some people, however, the symbolic plant might one day represent more than a kiss at Christmas time: It may mean better liver health. Researchers have found that a compound produced by a particular variety of the plant can help fight obesity-related liver disease in mice. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - December 17, 2014 Category: Science Source Type: news

Identification of genes and pathways involved in RCC
We combined differentially expressed genes, pathways and network analyses to gain new insights into the underlying molecular mechanisms of the disease development.12/17/2014 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - December 17, 2014 Category: Cancer & Oncology Source Type: news

PAX-8 expression in renal tumors
Immunohistochemical stains have greatly improved the diagnostic accuracy of renal cell carcinoma (RCC) for primary and distant tumours. We evaluate a marker that has recently been incorporated in clinical practice, PAX-8, in primary and metastatic RCCs.12/17/2014 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - December 17, 2014 Category: Cancer & Oncology Source Type: news

Changes in prostate-specific antigen, markers of bone metabolism and bone scans after treatment with radium-223
Scandinavian Journal of Urology, Ahead of Print. (Source: Scandinavian Journal of Urology)
Source: Scandinavian Journal of Urology - December 17, 2014 Category: Urology & Nephrology Tags: article Source Type: research

Sleep and partner-specific quality of life in partners of men with lower urinary tract symptoms compared with partners of men from the general population
Scandinavian Journal of Urology, Ahead of Print. (Source: Scandinavian Journal of Urology)
Source: Scandinavian Journal of Urology - December 17, 2014 Category: Urology & Nephrology Tags: article Source Type: research

Health-related quality of life, personality and choice of coping are related in renal cell carcinoma patients
Scandinavian Journal of Urology, Ahead of Print. (Source: Scandinavian Journal of Urology)
Source: Scandinavian Journal of Urology - December 17, 2014 Category: Urology & Nephrology Tags: article Source Type: research

Possible benefits of robot‐assisted rectal cancer surgery regarding urological and sexual dysfunction:: a systematic review and meta‐analysis
ConclusionAlthough there were few data and no randomized controlled trials the results of the review suggested that robot‐assisted surgery resulted in improved urogenital function than after laparoscopy.This article is protected by copyright. All rights reserved. (Source: Colorectal Disease)
Source: Colorectal Disease - December 17, 2014 Category: Gastroenterology Authors: Malene Broholm, Hans‐Christian Pommergaard, Ismail Gögenür Tags: Systematic Review Source Type: research

Assessment of the external validity of a predictive score for blood transfusion in liver surgery
ConclusionsIn the present population, the TRS appeared to serve as a weak predictor of perioperative transfusion. This study confirms that the external validity of the transfusion predictive score should be subject to further investigation before it can be implemented in clinical use. (Source: HPB: official journal of the International Hepato Pancreat Biliary Association)
Source: HPB: official journal of the International Hepato Pancreat Biliary Association - December 17, 2014 Category: Gastroenterology Authors: Sylvie Janny, Mathilde Eurin, Safi Dokmak, Amélie Toussaint, Olivier Farges, Catherine Paugam‐Burtz Tags: Original Article Source Type: research

Not just for the holidays, mistletoe could fight obesity-related liver disease
(American Chemical Society) Mistletoe hanging in doorways announces that the holidays are just around the corner. For some people, however, the symbolic plant might one day represent more than a kiss at Christmas time: It may mean better liver health. Researchers have found that a compound produced by a particular variety of the plant can help fight obesity-related liver disease in mice. Their study appears in ACS' Journal of Agricultural and Food Chemistry. (Source: EurekAlert! - Biology)
Source: EurekAlert! - Biology - December 17, 2014 Category: Biology Source Type: news

LIVER ALIGN (Chelidonium Majus, Cholesterinum, Arsenicum Album, Belladonna, Lycopodium Clavatum, Tarentula Hispana) Liquid [Evolution]
Updated Date: Dec 17, 2014 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))
Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) - December 17, 2014 Category: Drugs & Pharmacology Source Type: news

Match Reveals No Love for Nephrology (CME/CE)
(MedPage Today) -- A dwindling interest in nephrology fellowships has specialists pondering the viability of their field. (Source: MedPage Today Cardiovascular)
Source: MedPage Today Cardiovascular - December 17, 2014 Category: Cardiology Source Type: news

Prolonged complete remission of metastatic HER2-positive breast cancer after continuous trastuzumab treatment: a case report and review of the literature
We present a case of an 81-year-old patient with HER2-amplified metastatic breast cancer (MBC) in the liver. Following taxane-based chemotherapy in combination with trastuzumab after local treatment resulted in a complete radiological remission after 21 months of trastuzumab maintenance therapy. The patient remains in complete remission 6 years later and continues to receive trastuzumab as maintenance therapy. Prolonged remission in cases with complete response under trastuzumab-based regimens for metastatic HER2-positive breast cancer can be observed in some patients. Reviewing the few available cases published in the l...
Source: Targeted Oncology - December 17, 2014 Category: Cancer & Oncology Source Type: research

The association between retinal microvascular changes, metabolic risk factors, and liver histology in pediatric patients with non-alcoholic fatty liver disease (NAFLD)
Conclusions We found an association between metabolic parameters and nocturnal blood pressure on the retinal microvasculature among the obese children with NAFLD. Furthermore, for the first time, we report the positive relationship between hepatic fibrosis in pediatric NAFLD patients and the degree of retinopathy signs. (Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - December 17, 2014 Category: Gastroenterology Source Type: research

Entecavir vs Lamivudine for Prevention of Hepatitis B Virus Reactivation Among Patients With Untreated Diffuse Large B-Cell Lymphoma Receiving R-CHOP Chemotherapy A Randomized Clinical Trial
Conclusions and RelevanceAmong patients seropositive for the hepatitis B surface antigen with diffuse large B-cell lymphoma undergoing R-CHOP chemotherapy, the addition of entecavir compared with lamivudine resulted in a lower incidence of HBV-related hepatitis and HBV reactivation. If replicated, these findings support the use of entecavir in these patients.Trial Registrationsclinicaltrials.gov Identifier: NCT01793844; Chinese Clinical Trial Registry Identifier: CTR-TRC-11001687 (Source: JAMA)
Source: JAMA - December 17, 2014 Category: Journals (General) Source Type: research

Assessment of Outcomes of Hepatitis C Treatment—Reply
In Reply Dr Chavez-Tapia and colleagues raise an important clinical question. Is SVR the appropriate clinical end point with new treatments for HCV or should clinical outcomes be assessed? Clinical outcomes of HCV include progression of liver fibrosis, decompensated liver disease, occurrence of hepatocellular carcinoma, and mortality, all of which take years to develop. In the interferon era of HCV therapeutics, occurrence of SVR was correlated with improved liver-related and overall outcomes, including hepatocellular carcinoma. Long-term follow-up studies of patients who achieve SVR need to be performed to evaluate whethe...
Source: JAMA - December 17, 2014 Category: Journals (General) Source Type: research

Circulating microRNA as a diagnostic marker in populations with type 2 diabetes mellitus and diabetic complications
Publication date: Available online 16 December 2014 Source:Journal of the Chinese Medical Association Author(s): Hung-Yu Chien , Tai-Ping Lee , Chang-Yi Chen , Yen-Hui Chiu , Yi-Chun Lin , Lon-Shyong Lee , Wan-Chun Li Diabetes mellitus (DM) is a global health care issue resulting from hyperglycemia-mediated life-threatening complications. Although the use of glucose-lowering agents is routinely practiced, high dependence on medication leads to poor quality of life for DM patients. While it is still not feasible to precisely determine the critical timing when DM is truly established, perhaps the best way to reduce DM-asso...
Source: Journal of the Chinese Medical Association - December 17, 2014 Category: Journals (General) Source Type: research

Misconceptions and miscommunication among Spanish-speaking and English-speaking women with pelvic organ prolapse
Conclusions Our findings emphasize that women with POP have considerable misconceptions about their disease. In addition, there is miscommunication during the patient–physician interaction that leads to further confusion among Spanish-speaking and English-speaking women. Spending more time explaining the diagnosis of POP, rather than focusing solely on treatment options, may reduce miscommunication and increase patient understanding. (Source: International Urogynecology Journal)
Source: International Urogynecology Journal - December 17, 2014 Category: OBGYN Source Type: research

Impact de l’insuffisance rénale chronique et de la greffe rénale sur la fonction reproductive
Publication date: Available online 16 December 2014 Source:Gynécologie Obstétrique &amp; Fertilité Author(s): A.-S. Delesalle , G. Robin , F. Provôt , D. Dewailly , M. Leroy-Billiard , M. Peigné L’insuffisance rénale chronique est responsable de nombreux désordres métaboliques qui peuvent avoir des conséquences sur la fonction reproductive. Chez l’homme, l’insuffisance rénale chronique entraîne un hypogonadisme hypergonadotrope, une hyperprolactinémie, des altérations spermatiques, une baisse de la libido et une dysfonction érectile. La greffe rénale permet d’améliorer les paramètres spermati...
Source: Gynecologie Obstetrique and Fertilite - December 17, 2014 Category: OBGYN Source Type: research

Retrospective cohort study of portacaval lymphadenopathy identified on multidetector CT and implications for follow-up
Conclusions Development of malignancy is rare in patients with PCLA, either incidental or secondary to cirrhosis or chronic viral hepatitis. Our study suggests that no follow-up of PCLA is required in these settings. (Source: Abdominal Imaging)
Source: Abdominal Imaging - December 17, 2014 Category: Radiology Source Type: research

Hepatic arterial spin labelling MRI: an initial evaluation in mice
This study shows that preclinical HASL is feasible and exhibits good repeatability and reproducibility. Mean estimated liver perfusion was 2.2 ± 0.8 mL/g/min (mean ± standard error, n = 10), which agrees well with previous measurements using invasive approaches. Estimates of the variation gave a within‐session coefficient of variation (CVWS) of 7%, a between‐session coefficient of variation (CVBS) of 9% and a between‐animal coefficient of variation (CVA) of 15%. The within‐session Bland–Altman repeatability coefficient (RCWS) was 18% and the between‐session repeatability coefficient (RCBS) was 2...
Source: NMR in Biomedicine - December 17, 2014 Category: Radiology Authors: R. Ramasawmy, A. E. Campbell‐Washburn, J. A. Wells, S. P. Johnson, R. B. Pedley, S. Walker‐Samuel, M. F. Lythgoe Tags: Research article Source Type: research

Proprotein convertase subtilisin/kexin type 9 expression is transiently up-regulated in the acute period of myocardial infarction in rat
Conclusions: We firstly demonstrated that PCSK9 was transiently up-regulated in the acute period of AMI, which is also driven by transcriptional factors, SREBP-2 and HNF1alpha, suggesting that the role of PCSK9 in myocardial injury may be needed further study. (Source: BMC Cardiovascular Disorders)
Source: BMC Cardiovascular Disorders - December 17, 2014 Category: Cardiology Authors: Yan ZhangJun LiuSha LiRui-Xia XuJing SunYue TangJian-Jun Li Source Type: research

Mesenchymal stem (stromal) cells for treatment of ARDS: a phase 1 clinical trial
Publication date: Available online 17 December 2014 Source:The Lancet Respiratory Medicine Author(s): Jennifer G Wilson , Kathleen D Liu , Hanjing Zhuo , Lizette Caballero , Melanie McMillan , Xiaohui Fang , Katherine Cosgrove , Rosemary Vojnik , Carolyn S Calfee , Jae-Woo Lee , Angela J Rogers , Joseph Levitt , Jeanine Wiener-Kronish , Ednan K Bajwa , Andrew Leavitt , David McKenna , B Taylor Thompson , Michael A Matthay Background No effective pharmacotherapy for acute respiratory distress syndrome (ARDS) exists, and mortality remains high. Preclinical studies support the efficacy of mesenchymal stem (stromal) cells (M...
Source: The Lancet Respiratory Medicine - December 17, 2014 Category: Respiratory Medicine Source Type: research

Cigarette smoking is associated with a reduction in the risk of incident gout: results from the Framingham Heart Study original cohort
Conclusion. Cigarette smoking is associated with lower incidence of gout and this is not explained by differences in the prevalence of risk factors. The mechanistic underpinnings of this epidemiological finding merits further study. (Source: Rheumatology)
Source: Rheumatology - December 17, 2014 Category: Rheumatology Authors: Wang, W., Krishnan, E. Tags: Crystal Arthritis CLINICAL SCIENCE Source Type: research

Anatomical consideration for safe pericardiocentesis assessed by three-dimensional computed tomography: Should an anterior or posterior approach be used?
Conclusions Performing subxiphoid pericardiocentesis is anatomically safer via the anterior approach than via the posterior approach. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - December 17, 2014 Category: Cardiology Source Type: research

Totally laparoscopic ALPPS in the treatment of cirrhotic hepatocellular carcinoma
Conclusion Totally laparoscopic ALPPS is feasible, with satisfactory short-term efficacy, conforming to the “No Touch” principle. ALPPS may be safe for the treatment of HCC in cirrhotic patients, but the interval between the two stages may be extended. (Source: Surgical Endoscopy)
Source: Surgical Endoscopy - December 17, 2014 Category: Surgery Source Type: research

Prognostic value of the platelet to lymphocyte ratio change in liver cancer
This study was designed to evaluate the prognostic value of ΔPLR in patients with hepatitis B virus (HBV)-related small HCC who underwent liver resection. (Source: Journal of Surgical Research)
Source: Journal of Surgical Research - December 17, 2014 Category: Surgery Authors: Wei Peng, Chuan Li, Wen-Jiang Zhu, Tian-Fu Wen, Lv-Nan Yan, Bo Li, Wen-Tao Wang, Jia-Yin Yang Source Type: research

Choledochocele: A Case Report and Discussion of Diagnosis Criterias
Publication date: Available online 16 December 2014 Source:Journal of Pediatric Surgery Case Reports Author(s): Linlin Zhu , Zhibao Lv , Jiangbin Liu , Weijue Xu Abstract A 6-year-old girl presented with intermittent abdominal pain, without jaundice and liver damage. Clinical and preoperative imaging examinations suggested a diagnosis of duodenal duplication. During surgery, the patient was diagnosed with a rare type of choledochal cyst- choledochocele (type 3b). The authors emphasize that in children, choledochocele should be included in the list of conditions in the differential diagnosis of cystic lesions located in t...
Source: Journal of Pediatric Surgery Case Reports - December 17, 2014 Category: Surgery Source Type: research

Hepatocyte growth factor signalizes peritoneal membrane failure in peritoneal dialysis
Background: Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF). Our aim was to assess the relationship between effluent HGF with UF profile, free water transport (FWT) and small-solute transport. Methods: We performed 4-hour, 3.86% PET with additional UF measurement at 60 minutes in 68 PD patients. MTACcreatinine, FWT, small-pore ultrafiltration, and effluent HGF were quantified. Results: Effluent HGF negatively correlated with UF (r = -0.80, p = 0.009) and FWT (r = -...
Source: BMC Nephrology - December 17, 2014 Category: Urology & Nephrology Authors: Ana BernardoJosé OliveiraOlívia SantosMaria CarvalhoAntónio CabritaAnabela Rodrigues Source Type: research

The increased transglutaminase 2 expression levels during initial tumorigenesis predict increased risk of metastasis and decreased disease-free and cancer-specific survivals in renal cell carcinoma
Conclusions The increased expression of TG2 in primary tumor predicts metastasis in RCC patients and is also associated with a decrease in disease-free and cancer-specific survival outcomes. (Source: World Journal of Urology)
Source: World Journal of Urology - December 17, 2014 Category: Urology & Nephrology Source Type: research

Evaluation of national trends in the utilization of partial nephrectomy in relation to the publication of the American urological association guidelines for the management of clinical T1 renal masses
Conclusion: We noted a 6.4% absolute increase in PN after release of the AUA guidelines on clinical T1 renal mass was published; however, the rate of increase was not likely associated with guideline release. The rate of PN performed is increasing; however, further investigation regarding medical decision-making surrounding PN is needed. (Source: BMC Urology)
Source: BMC Urology - December 17, 2014 Category: Urology & Nephrology Authors: Michael LissSong WangKerrin PalazziRamzi JabajiNishant PatelHak LeeJ ParsonsIthaar Derweesh Source Type: research

Re: Impact of Visceral Fat Ratio on Sleep-Related Erection: A Retrospective Study of Elderly Patients
M. Takeuchi, S. Hisasue, K. Hashimoto, T. Tsukamoto and N. Masumori (Source: The Journal of Urology)
Source: The Journal of Urology - December 17, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research

Re: Prevalence and Determinants of Use of Potentially Inappropriate Medications in Elderly Inpatients: A Prospective Study in a Tertiary Healthcare Setting
K. Undela, D. Bansal, S. D’Cruz, A. Sachdev and P. Tiwari (Source: The Journal of Urology)
Source: The Journal of Urology - December 17, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research

Re: American Geriatrics Society Identifies another Five Things that Healthcare Providers and Patients Should Question
AGS Choosing Wisely Workgroup (Source: The Journal of Urology)
Source: The Journal of Urology - December 17, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research