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This page shows you the most recent publications within this specialty of the MedWorm directory. This is page number 12.

Re: Prostate Volume Correlates with Diabetes in Elderly Benign Prostatic Hyperplasia Patients
X. Qu, Z. Huang, X. Meng, X. Zhang, L. Dong and X. Zhao (Source: The Journal of Urology)
Source: The Journal of Urology - October 15, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research

Re: Cost-Effectiveness of Cranberry Capsules to Prevent Urinary Tract Infection in Long-Term Care Facilities: Economic Evaluation with a Randomized Controlled Trial
W. B. van den Hout, M. A. Caljouw, H. Putter, H. J. Cools and J. Gussekloo (Source: The Journal of Urology)
Source: The Journal of Urology - October 15, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research

Re: Effectiveness of Cranberry Capsules to Prevent Urinary Tract Infections in Vulnerable Older Persons: A Double-Blind Randomized Placebo-Controlled Trial in Long-Term Care Facilities
M. A. Caljouw, W. B. van den Hout, H. Putter, W. P. Achterberg, H. J. Cools and J. Gussekloo (Source: The Journal of Urology)
Source: The Journal of Urology - October 15, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research

Re: Clinical Outcomes and Patient Satisfaction Rates among Elderly Male Aged ≥75 Years with Inflatable Penile Prosthesis Implant for Medically Refractory Erectile Dysfunction
E. Chung, M. Solomon, L. DeYoung and G. B. Brock (Source: The Journal of Urology)
Source: The Journal of Urology - October 15, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research

Re: Determinants of Sexual Activity in Four Birth Cohorts of Swedish 70-Year-Older Examined 1971-2001
N. Beckman, M. Waern, S. Östling, V. Sundh and I. Skoog (Source: The Journal of Urology)
Source: The Journal of Urology - October 15, 2014 Category: Urology & Nephrology Authors: Tomas L. Griebling Tags: Urological Survey Source Type: research

Overdetection of recurrence after radical prostatectomy: estimates based on patient and tumor characteristics.
CONCLUSIONS: This analysis indicates that PSA-R after RP may be overdetected, with risk depending on patient age and tumor characteristics. The potential for overdetection of recurrence confirms the need for approaches to determine whether and when to initiate salvage therapies. Clin Cancer Res; 20(20); 5302-10. ©2014 AACR. PMID: 25320374 [PubMed - in process] (Source: Clinical Cancer Research)
Source: Clinical Cancer Research - October 15, 2014 Category: Cancer & Oncology Authors: Xia J, Trock BJ, Gulati R, Mallinger L, Cooperberg MR, Carroll PR, Carter HB, Etzioni R Tags: Clin Cancer Res Source Type: research

Comparison of captive lifespan, age-associated liver neoplasias and age-dependent gene expression between two annual fish species: Nothobranchius furzeri and Nothobranchius korthause.
In conclusion, our data suggest that the different ageing rate of two species of the same genus could be used as novel tool to investigate and better understand the genetic bases of some general mechanism leading to the complex ageing process, providing a strategy to unravel some of the genetic mechanisms regulating longevity and age-associate pathologies including neoplasias. PMID: 25315356 [PubMed - as supplied by publisher] (Source: Biogerontology)
Source: Biogerontology - October 15, 2014 Category: Geriatrics Authors: Baumgart M, Di Cicco E, Rossi G, Cellerino A, Tozzini ET Tags: Biogerontology Source Type: research

Population pharmacokinetic-pharmacodynamic (PKPD) modelling to describe the effects of paracetamol and N-acetylcysteine on the International Normalised Ratio (INR).
This article is protected by copyright. All rights reserved. PMID: 25316328 [PubMed - as supplied by publisher] (Source: Clinical and Experimental Pharmacology and Physiology)
Source: Clinical and Experimental Pharmacology and Physiology - October 15, 2014 Category: Drugs & Pharmacology Authors: Owens KH, Medlicott NJ, Zacharias M, Whyte IM, Buckley NA, Reith DM Tags: Clin Exp Pharmacol Physiol Source Type: research

Periconceptional undernutrition modifies endocrine profiles and hepatic gene expression in sheep
This study investigated whether a 22‐day period of undernutrition (half maintenance) could affect maternal endocrine responses and liver gene expression during early pregnancy (day 7). Thirty‐five ewes were fed 1.5 (n = 15) or 0.5 (n = 20) their maintenance requirements and slaughtered on day 7 of the oestrus cycle or pregnancy (oestrus = day 0). Insulin, IGF, leptin and non‐esterified fatty acids (NEFA) were determined on days −14, 0 and 7. Transcripts of the IGF family and adipokines receptors were determined in the liver by real‐time RT‐PCR. Underfed animals presented lower body weight and body conditi...
Source: Journal of Animal Physiology and Animal Nutrition - October 15, 2014 Category: Zoology Authors: V. Brun, A. Meikle, A. Casal, M. Sequeira, I. Contreras‐Solís, M. Carriquiry, F. Forcada, C. Sosa, J.A. Abecia Tags: Original Article Source Type: research

High fat diet and Angiotensin‐II Induced Aneurysm Concurrently Elicits Splenic Hypertrophy
ConclusionsOur study provides evidence that Ang II infusion and high fat supplementation induces AAA that has pathological implications to the spleen. The use of β‐carotene but not α‐tocopherol as an antioxidant markedly ameliorates the pathological changes in spleen.This article is protected by copyright. All rights reserved. (Source: European Journal of Clinical Investigation)
Source: European Journal of Clinical Investigation - October 15, 2014 Category: Journals (General) Authors: Kaliappan Gopal, Perumal Nagarajan, Esaki M Shankar, Tunku Kamarul, Jerald M Kumar Tags: Original Article Source Type: research

Portulaca oleracea reduces triglyceridemia, cholesterolemia, and improves lecithin: cholesterol acyltransferase activity in rats fed enriched-cholesterol diet
Conclusion: Portulaca oleracea reduces triglyceridemia, cholesterolemia, and improves reverse cholesterol transport in rat fed enriched-cholesterol diet, contributing to anti-atherogenic effects. (Source: Phytomedicine)
Source: Phytomedicine - October 15, 2014 Category: Drugs & Pharmacology Authors: Y. Zidan, S. Bouderbala, F. Djellouli, M.A. Lacaille-Dubois, M. Bouchenak Tags: Cardiovascular System Source Type: research

Combining metabolomic analysis and microarray gene expression analysis in the characterization of the medicinal plant Chelidonium majus L
Conclusion: Different manufacturing processes lead to different herbal preparations. A systems biology approach combining a metabolomic plant analysis with a functional characterization by gene expression profiling in HepG2 cells is an appropriate strategy to characterize variations in plant extracts. Safety assessments of herbal substances may benefit from such complementary analyses. (Source: Phytomedicine)
Source: Phytomedicine - October 15, 2014 Category: Drugs & Pharmacology Authors: A. Orland, K. Knapp, G.M. König, G. Ulrich-Merzenich, W. Knöß Tags: Methods Source Type: research

Cytotoxicity and modes of action of 4′-hydroxy-2′,6′-dimethoxychalcone and other flavonoids toward drug-sensitive and multidrug-resistant cancer cell lines
Conclusions: Chalcone 1 was the best tested cytotoxic molecule and further studies will be performed in order to envisage its possible use in the fight against multifactorial resistant cancer cells. (Source: Phytomedicine)
Source: Phytomedicine - October 15, 2014 Category: Drugs & Pharmacology Authors: Victor Kuete, Antoine H.L. Nkuete, Armelle T. Mbaveng, Benjamin Wiench, Hippolyte K. Wabo, Pierre Tane, Thomas Efferth Tags: Oncology and Hematology Source Type: research

Potential beta interferon side effects
The MHRA, the UK drug regulator, has issued a drug safety update from on risk of blood and kidney disorders following treatment with beta interferon. MHRA Beta interferon - A to Z of MS (Source: Multiple Sclerosis Trust)
Source: Multiple Sclerosis Trust - October 14, 2014 Category: Neurology Source Type: news

FDA Clears Urinary Prosthesis for WomenFDA Clears Urinary Prosthesis for Women
The inFlow Intraurethral Valve-Pump is a replaceable device for women with impaired detrusor contractility. FDA Approvals (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 14, 2014 Category: Consumer Health News Tags: Urology News Alert Source Type: news

Survival and Predictive Factors of Lethality in Hemodyalisis: D/I Polymorphism of The Angiotensin I-Converting Enzyme and of the Angiotensinogen M235T Genes
Conclusions: The survival of hemodialysis patients is likely to be influenced by the TT of the angiotensinogen M235T gene. Fundamento: Os pacientes em hemodiálise continuam tendo um significativo aumento na morbiletalidade, especialmente a causada por doenças cardiovasculares. A análise dos fatores genéticos ligados ao sistema renina-angiotensina que influenciam na sobrevivência destes pacientes poderá ajudar na busca por melhores resultados. Objetivo: Avaliar a sobrevida em hemodialisados e sua associação com polimorfismo dos genes do sistema reninaangiotensina: deleção/inserção do gene que codifica a enzima ...
Source: Arquivos Brasileiros de Cardiologia - October 14, 2014 Category: Cardiology Source Type: research

Using a novel biological clock, UCLA researchers find that obesity accelerates aging of the liver
Using a recently developed biomarker of aging known as an epigenetic clock, UCLA researchers working closely with a German team of investigators have found for the first time that obesity greatly accelerates aging of the liver. This finding could explain the early onset of many age-related diseases, including liver cancer, in people who are obese. Although it had long been suspected that obesity ages a person faster, it hadn’t been possible to prove the theory until now, said study first author Steve Horvath, a professor who holds joint appointments in human genetics at the David Geffen School of Medicine at UCLA and in ...
Source: UCLA Newsroom: Health Sciences - October 14, 2014 Category: Universities & Medical Training Source Type: news

Does the kidney play an important role in the generation of ventricular arrhythmias and sudden cardiac death?
(Source: Clinical Research in Cardiology)
Source: Clinical Research in Cardiology - October 14, 2014 Category: Cardiology Source Type: research

Bacteriostasis evaluation of the different soaking solutions in perineal skin preparation before the male urethral open operation: a randomized controlled trial
In conclusion, combination of 0·1% povidone iodine and 1·6% saline solution for the preoperative skin preparation of male open urethral operation is safe and efficient. (Source: International Journal of Urological Nursing)
Source: International Journal of Urological Nursing - October 14, 2014 Category: Urology & Nephrology Authors: Li Ma, Ling Liu, Ye Tian, Yinqiong Peng, Kunjie Wang, Tao Wu, Changqing Liu Tags: Research Paper Source Type: research

Valsalva leak point pressure-associated Q-tip angle and simple female stress urinary incontinence symptoms
Conclusions In simple female SUI, VLPP is associated with the Q-tip angle and Stamey grade, which may help to reduce some of urodynamic items. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 14, 2014 Category: Urology & Nephrology Source Type: research

Outcomes of stent-change therapy for bilateral malignancy-related ureteral obstruction
Conclusions To preserve renal function, patients with bilateral malignant ureteral obstruction, especially those aged 55 or more or with diabetes or poor baseline renal function, should be considered for early PCN conversion in the dominant functional kidney or both. (Source: International Urology and Nephrology)
Source: International Urology and Nephrology - October 14, 2014 Category: Urology & Nephrology Source Type: research

PCNL in the twenty-first century: role of Microperc, Miniperc, and Ultraminiperc
Conclusion The newer techniques with Miniperc are suited for stones 1.5–2 cm in size. Microperc and Ultraminiperc may be suitable for stone sizes <1.5 cm. These are also suited for special situations such as diverticular stones and pediatric moderate-sized stones. The indications of these newer techniques compete with those of extracorporeal shockwave lithotripsy and flexible ureteroscopy. (Source: World Journal of Urology)
Source: World Journal of Urology - October 14, 2014 Category: Urology & Nephrology Source Type: research

Meet Kidney Cancer Survivors!
10/14/2014 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 14, 2014 Category: Cancer & Oncology Source Type: news

Triple immunosuppressive therapy in steroid resistant nephrotic syndrome children with tacrolimus resistant or tacrolimus sensitive but frequently relapsing
ConclusionTriple‐combination therapy with Pre + TAC + CTX/MMF/LEF is effective for short‐term response and 1‐year remission, without significant additional side‐effects seen in children with steroid‐resistant and tacrolimus‐resistant or tacrolimus‐sensitive but frequent relapsing nephrotic syndrome. Further study for evaluating long‐term efficacy & safety of triple‐combination therapy with Pre+TAC+CTX/MMF/LEF would be necessary for these patients. (Source: Nephrology)
Source: Nephrology - October 14, 2014 Category: Urology & Nephrology Authors: Boying Wu, Jianhua Mao, Huijun Shen, Haidong Fu, Jingjing Wang, Aimin Liu, Weizhong Gu, Qiang Shu, Lizhong Du Tags: Original Article Source Type: research

In situ viability detection assays induce heat‐shock protein 70 expression in spermatozoa without affecting the chromatin integrity
Summary To differentiate dead spermatozoa from viable but immotile spermatozoa, several techniques are being used during ICSI. As processed spermatozoa from poor‐quality ejaculate are confronted with a higher risk of experiencing stress on exposure to altered osmotic conditions or chemicals, this study was undertaken to determine the expression of stress response gene Hsp70 and chromatin integrity in spermatozoa subjected to in situ viability assays such as hypo‐osmotic swelling (HOS) test, modified hypo‐osmotic swelling (M‐HOS) test and pentoxifylline in 25 fresh and frozen–thawed asthenozoospermic ejaculates. R...
Source: Andrologia - October 14, 2014 Category: Urology & Nephrology Authors: Y. Asokan, S. D. Honguntikar, S. Uppangala, S. R. Salian, D. Kumar, G. Kalthur, S. K. Adiga Tags: Original Article Source Type: research

How metastases develop in the liver
Most tumors are only fatal if the cancer cells spread in the body and form secondary tumors, known as metastases, in other organs, such as the liver. Scientists have now shown that increased amounts of a particular protein in the liver create favorable conditions for the implantation of cancer cells and thus for the formation of metastases. The researchers have already succeeded in preventing these processes in an animal model. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 14, 2014 Category: Science Source Type: news

Kidney Cancer Journal: Autumn 2014
10/14/2014 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - October 14, 2014 Category: Cancer & Oncology Source Type: news

Hepatic and perihepatic involvement of female genital diseases and pregnancy: a review
Abstract The liver is rarely involved in female genital diseases or pregnancy. Peripheral hepatic and perihepatic lesions are mainly due to the progression of genital malignancies, usually ovarian cancer. It should be distinguished from other malignant and non-malignant lesions. In all clinical situations, liver involvement is a sign of distant extension or dissemination of female genital diseases. Therefore, accurate detection and characterization of hepatic and perihepatic involvement on imaging is of clinical importance and often changes patient management. (Source: Abdominal Imaging)
Source: Abdominal Imaging - October 14, 2014 Category: Radiology Source Type: research

Painful Blistering on the Dorsal Hands
By Wold, Lindsey; Lampel, Heather P. MD, MPH A 58-year-old man presented with an eight-month history of nail changes and painful blisters on the dorsal surface of his hands. He noticed these findings after working in his yard. He smokes three packs of cigarettes daily, and receives hemodialysis three times weekly for ESRD secondary to polycystic kidney disease. His medications included simvastatin, omeprazole, minoxidil, calcium, and a vitamin B complex.   The patient was well-appearing, had stable vitals, and wasn't in any acute distress. Skin examination revealed shallow, well-defined erosions, some with central crus...
Source: The Case Files - October 14, 2014 Category: Emergency Medicine Tags: Blog Posts Source Type: research

Effect of fish and krill oil supplementation on glucose tolerance in rabbits with experimentally induced obesity
Conclusion The present results indicate that FO and KO supplementation decreases fasting blood glucose and improves glucose tolerance in obese New Zealand white rabbits. This could be ascribed to the ameliorated insulin sensitivity and insulin secretion and modified gene expressions of some key enzymes involved in β-oxidation and lipogenesis in liver and skeletal muscle. (Source: European Journal of Nutrition)
Source: European Journal of Nutrition - October 14, 2014 Category: Nutrition Source Type: research

Prognosis of Patients With HCC in the Non-cirrhotic LiverPrognosis of Patients With HCC in the Non-cirrhotic Liver
In patients with non-cirrhotic livers, who's most at risk for developing hepatocellular carcinoma and how do they generally fare? BMC Gastroenterology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2014 Category: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

25-Hydroxyvitamin D and Incidence of Kidney Stones25-Hydroxyvitamin D and Incidence of Kidney Stones
While dietary supplementation with Vitamin D is being encouraged by many, its been suggested that higher serum levels may increase risk of kidney stones. Is there cause for concern? American Journal of Public Health (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2014 Category: Consumer Health News Tags: Nephrology Journal Article Source Type: news

Chronic Kidney Disease and ICD Related ComplicationsChronic Kidney Disease and ICD Related Complications
Find out more about the association between kidney function and the occurrence of ICD related complications. Journal of Cardiovascular Electrophysiology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - October 14, 2014 Category: Consumer Health News Tags: Cardiology Journal Article Source Type: news

[Correspondence] Chronic kidney disease and stroke
We appreciate the idea of cerebrorenal interaction, as proposed by Toyoda and colleagues in their recent Review, because it raises an important clinical issue with respect to chronic kidney disease in patients with stroke and cerebrovascular disease. The authors describe the mechanisms by which kidney disease might increase the risk of stroke and subclinical cerebral abnormalities, and affect cognitive function. However, the effect of stroke or cerebrovascular disease on renal function has scarcely been explored, which makes the comprehensive description of this two-way interaction more challenging than that of its cardiol...
Source: Lancet Neurology - October 14, 2014 Category: Neurology Authors: Cheng-Yang Hsieh, Huey-Juan Lin, Chih-Hung Chen, Edward Chia-Cheng Lai, Yea-Huei Kao Yang Tags: Correspondence Source Type: research

[Correspondence] Chronic kidney disease and stroke–Authors' reply
We thank Cheng-Yang Hsieh and colleagues for their interest in our Review. The effect of stroke on kidney function is an important point to consider in terms of cerebrorenal interactions. In 7 068 334 patients admitted to hospital with acute ischaemic stroke as part of the US Nationwide Inpatient Sample from 2002 to 2010, 372 223 patients had acute renal failure that was independently associated with moderate to severe disability (odds ratio [OR] 1·3, 95% CI 1·3–1·4), intracerebral haemorrhage (1·4, 1·3–1·6), and death (2·2, 2·0–2·2) after multivariable adjustment. (Source: Lancet Neurology)
Source: Lancet Neurology - October 14, 2014 Category: Neurology Authors: Kazunori Toyoda, on behalf of all authors Tags: Correspondence Source Type: research

Undetectable HCV‐RNA at treatment‐week 8 results in high‐sustained virological response in HCV G1 treatment‐experienced patients with advanced liver disease: the International Italian/Spanish Boceprevir/Peginterferon/Ribavirin Name Patients Program
Summary In many countries, first‐generation protease inhibitors (PIs)/peginterferon/ribavirin (P/R) still represent the only treatment option for HCV‐infected patients. Subjects with advanced disease and previous failure to P/R urgently need therapy, but they are under‐represented in clinical trials. All treatment‐experienced F3/4 Metavir patients who received boceprevir (BOC)+P/R in the Italian–Spanish Name Patient Program have been included in this study. Multivariate logistic regression analysis (MLR) was used to identify baseline and on‐treatment predictors of SVR and adverse events (AEs). Four hundred and ...
Source: Journal of Viral Hepatitis - October 14, 2014 Category: Infectious Diseases Authors: S. Bruno, S. Bollani, A. L. Zignego, J. M. Pascasio, C. Magni, A. Ciancio, M. Caremani, A. Mangia, S. Marenco, S. Piovesan, L. Chemello, S. Babudieri, A. Moretti, F. Gea, C. Colletta, R. Perez‐Alvarez, X. Forns, J. R. Larrubina, J. Arenas, J. Crespo, V. Tags: Original Article Source Type: research

Management of ulcerative colitis pre- and post-liver transplant for primary sclerosing cholangitis: two case reports and review of literature
We present two cases of UC-PSC with variable severity of liver disease and discuss the available data on the management of UC pre- and post-liver transplant. A PubMed search was conducted using various keyword combinations looking for studies involving patients with UC-PSC pre- and post-liver transplant. We reviewed and summarized the available literature on the course of UC in patients with PSC-related cirrhosis pre- and post-transplant and risk of colorectal neoplasia post-transplant. Finally, we summarize the available data on the medical and surgical management of UC pre- and post-liver transplant and the effect of tra...
Source: International Journal of Colorectal Disease - October 14, 2014 Category: Gastroenterology Source Type: research

Big Spleens and Hypersplenism: Fix it or forget it?
This article is protected by copyright. All rights reserved. (Source: Liver International)
Source: Liver International - October 14, 2014 Category: Gastroenterology Authors: Thomas D Boyer, Shahid Habib Tags: Review Source Type: research

Obesity May Speed Aging of the Liver, Study Suggests
Title: Obesity May Speed Aging of the Liver, Study SuggestsCategory: Health NewsCreated: 10/13/2014 12:00:00 AMLast Editorial Review: 10/14/2014 12:00:00 AM (Source: MedicineNet Weight Management General)
Source: MedicineNet Weight Management General - October 14, 2014 Category: Eating Disorders and Weight Management Source Type: news

Rats of New York and the diseases they carry
(Columbia University's Mailman School of Public Health) In the first study to look at would-be diseases carried by New York City rats, scientists at the Center for Infection and Immunity at Columbia University's Mailman School of Public Health identified bacterial pathogens, including E. coli, Salmonella, and C. difficile, that cause mild to life-threatening gastroenteritis in people; Seoul hantavirus, which causes Ebola-like hemorrhagic fever and kidney failure in humans; and the closest relative to human hepatitis C. Results appear in the journal mBio. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - October 14, 2014 Category: Global & Universal Source Type: news