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Urology & Nephrology Urology & Nephrology OPML fileThis is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. Urology & Nephrology RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. subscribe with MyMedWormSubscribe to this data using MyMedWorm.subscribe with GoogleReaderSubscribe to this data using GoogleReader.subscribe with BloglinesSubscribe to this data using Bloglines.subscribe with MyYahooSubscribe to this data using MyYahoo.

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203194 records returned

Osmotic Stress Induces the Expression of VvMAP Kinase Gene in Grapevine (Vitis vinifera L.)email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abiotic stress adversely affects the growth of grapevine plants. In order to study the early expression changes of genes particularly involved in signal transduction upon salt and drought stresses in grapevines, ESTs derived from a suppressive subtractive hybridization approach (SSH) were selected for expression studies. We were particularly interested in the expression behaviour of the MAP kinase cDNA clone identified by differential screening of the salt-stressed SSH libraries. Interestingly, VvMAP kinase transcript showed a differential expression towards salt and drought treatment in the salt tolerant cultivar Razegui....
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Lung Separation in the Morbidly Obese Patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Lung separation techniques in the morbidly obese patient undergoing thoracic or esophageal surgery may be at risk of complications during airway management. Access to the airway in the obese patient can be a challenge because they have altered airway anatomy, including a short and redundant neck, limited neck extension and accumulation of fat deposition in the pharyngeal wall contributing to difficult laryngoscopy. Securing the airway is the first priority in these patients followed by appropriate techniques for lung separation with the use of a single-lumen endotracheal tube and a bronchial blocker or another alternative ...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Bronchoscopy in Rural Areas?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Quality of bronchoscopy performed by one single pulmonologist in a scarcely populated subarctic area was compared to the guidelines provided by the British Thoracic Society (BTS). 103 patients underwent bronchoscopy. Diagnostic yield was increased to 76.6% when the first bronchoscopy was supplemented by bronchial washing fluid and brush cytology and to 86.7% (BTS guidelines >80%) after a second bronchoscopy. Median time from referral to bronchoscopy was 10 days and 8 days from positive bronchoscopy to operative referral to another hospital. 1% of patients that underwent transbronchial lung biopsy had minor complica...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Fetuin A Concentration in the Second Trimester Amniotic Fluid of Fetuses with Trisomy 21 Appears to Be Lower: Phenotypic Considerationsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion. Lower levels of fetuin A in trisomy 21 may indicate an association with altered metabolic pathways in this early stage that could potentially be associated with features of the syndrome, such as growth restriction or impaired osteogenesis. (Source: Advances in Urology)
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Validation of the Antiproliferative Effects of Organic Extracts from the Green Husk of Juglans regia L. on PC-3 Human Prostate Cancer Cells by Assessment of Apoptosis-Related Genesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study was undertaken to investigate the effect of walnut green husk extracts on cell proliferation and to determine the possible molecular mechanism of extract-induced cell death by quantifying the expression of Bcl-2, Bax, caspases-3, and Tp53. PC-3 human prostate cancer cells. In this study, we found that green husk extracts suppressed proliferation and induced apoptosis in a dose- and time-dependent manner by modulating expression of apoptosis-related genes. This involved DNA fragmentation (determined by TUNEL assay) and significant changes in levels of mRNA and the expression of corresponding proteins. An increase...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Oral Haemangiomaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Vascular anomalies comprise a widely heterogeneous group of tumours and malformations. Haemangioma is the most common benign tumour of vascular origin of the head and neck region. The possible sites of occurrence in oral cavity are lips, tongue, buccal mucosa, and palate. Despite its benign origin and behaviour, it is always of clinical importance to the dental profession and requires appropriate management. This case study reports a rare case of capillary haemangioma on the palatal gingiva in a 14-year-old female. (Source: Advances in Urology)
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Hemorrhagic Shock as a Sequela of Splenic Rupture in a Patient with Infectious Mononucleosis: Focus on the Potential Role of Salicylatesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Despite the fact that the vast majority of splenic ruptures are traumatic, infectious mononucleosis has been incriminated as a major predisposing factor that affects the integrity of the spleen, thus causing atraumatic ruptures and life-threatening hemorrhages. Herein we present a case of a 23-year-old Caucasian male who underwent an emergency laparotomy for acute abdomen and hemorrhagic shock, caused by spontaneous splenic rupture secondary to infectious mononucleosis. The potential role of salicylates in the development of a hemorrhagic complication in a patient with infectious mononucleosis is discussed. (Source: Advances in Urology)
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Effect of Land Application of Phosphorus-Saturated Gypsum on Soil Phosphorus in a Laboratory Incubationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The objective of this study was to evaluate what effect soil amendment with gypsum would have on soil P concentrations and forms in a laboratory incubation experiment. Gypsum was saturated at two levels with P, and applied to a silt loam and a sandy loam at two rates. The treated soils were incubated in the laboratory at 25°C, and samples were collected on eight dates between 0 and 183 days after amendment. Spent gypsum application did not significantly increase soil water-extractable or Mehlich 3 P when applied at typical agronomic rates. This appears to be a viable strategy to remove P from agricultural drainage wat...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Spermatic Cord Lymphoma: A Case Report and Literature Reviewemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Spermatic cord lymphoma is a rare lethal disease. It has a poor prognosis even in stage I or II disease when treated locally, therefore, multidisciplinary treatment for early stage is recommended. On the other hand, the treatment of choice for stage III or IV spermatic cord lymphoma remains to be determined. It is said that spermatic cord lymphoma is clinicopathologically similar to primary testicular lymphoma, therefore the treatment of spermatic cord lymphoma has often been determined by reference to the recommended treatment for primary testicular lymphoma. Here we report a new case of spermatic cord lymphoma, which was...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Skin Graftemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Skin graft is one of the most indispensable techniques in plastic surgery and dermatology. Skin grafts are used in a variety of clinical situations, such as traumatic wounds, defects after oncologic resection, burn reconstruction, scar contracture release, congenital skin deficiencies, hair restoration, vitiligo, and nipple-areola reconstruction. Skin grafts are generally avoided in the management of more complex wounds. Conditions with deep spaces and exposed bones normally require the use of skin flaps or muscle flaps. In the present review, we describe how to perform skin grafting successfully, and some variation of ski...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Surgical Treatment of Persistent Fetal Vasculature and Visual Rehabilitation: One-Year Followupemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We present the management and postoperative course of a persistent fetal vasculature (PFV) case. A four-year-old girl visited the Eye Department of Hippokration, General Hospital of Thessaloniki due to reduced visual acuity of her left eye. She was diagnosed with PFV and underwent surgery (lensectomy, capsulorhexis of the posterior capsule, insertion of an intraocular lens in the posterior chamber, and posterior vitrectomy) in order to dissect the PFV. Along with the postoperative medical care, she underwent intensive treatment for amblyopia. The postoperative course was uncomplicated, and the visual acuity of her left eye...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Compactly Supported Curvelet-Type Systemsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
We study a flexible method for constructing curvelet-type frames. These curvelet-type systems have the same sparse representation properties as curvelets for appropriate classes of smooth functions, and the flexibility of the method allows us to give a constructive description of how to construct curvelet-type systems with a prescribed nature such as compact support in direct space. The method consists of using the machinery of almost diagonal matrices to show that a system of curvelet molecules which is sufficiently close to curvelets constitutes a frame for curvelet-type spaces. Such a system of curvelet molecules can th...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

mRNA 3′ End Processing Factors: A Phylogenetic Comparisonemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Almost all eukaryotic mRNAs possess 3′ ends with a polyadenylate (poly(A)) tail. This poly(A) tail is not encoded in the genome but is added by the process of polyadenylation. Polyadenylation is a two-step process, and this process is accomplished by multisubunit protein factors. Here, we comprehensively compare the protein machinery responsible for polyadenylation of mRNAs across many evolutionary divergent species, and we have found these protein factors to be remarkably conserved in nature. These data suggest that polyadenylation of mRNAs is an ancient process. (Source: Advances in Urology)
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Proposed Configurations for the Use of Smart Dampers with Bracings in Tall Buildingsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This paper presents wind-induced response reduction in a very slender building using smart dampers with proposed bracings-lever mechanism system. The building presents a case study of an engineered design that is instructive. The paper shows that shear response and flexural response of tall buildings present two very different cases for vibration suppression. Smart dampers are implemented optimally in the building to reduce its response in the lateral directions for both structural safety and occupant comfort concerns. New bracings-lever mechanism configurations are proposed for the dampers to improve their performance. Th...
Source: Advances in Urology - February 6, 2012 Category: Urology & Nephrology Source Type: research

Cryoablation vs radiofrequency ablation for the treatment of renal cell carcinoma: a meta‐analysis of case series studiesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CONCLUSIONS• This review shows that both ablation therapies have similar efficacy and complication rates.• There is urgency for performing clinical trials with long‐term data to establish which intervention is most suitable for the treatment of small renal masses. (Source: BJU International)
Source: BJU International - February 6, 2012 Category: Urology & Nephrology Authors: Regina El DibNaji J. ToumaAnil Kapoor Source Type: research

Evaluation of a transplantation specialty pharmacy program.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Conclusion A TSP program provided a high level of satisfaction to patients and health care providers, may have influenced some clinical outcomes, and served as a source of positive margin for its institution. PMID: 22302259 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - February 6, 2012 Category: Drugs & Pharmacology Authors: Hlubocky JM, Stuckey LJ, Schuman AD, Stevenson JG Tags: Am J Health Syst Pharm Source Type: research

Coffee Consumption Reduces Fibrosis Risk In Those With Fatty Liver Diseaseemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Caffeine consumption has long been associated with decreased risk of liver disease and reduced fibrosis in patients with chronic liver disease. Now, newly published research confirms that coffee caffeine consumption reduces the risk of advanced fibrosis in those with nonalcoholic fatty liver disease (NAFLD). Findings published in the February issue of Hepatology, a journal of the American Association for the Study of Liver Diseases, show that increased coffee intake, specifically among patients with nonalcoholic steatohepatitis (NASH), decreases risk of hepatic fibrosis... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 6, 2012 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

For Patients With Primary Biliary Cirrhosis, Rituximab A Possible Treatment Optionemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An open-label study of rituximab, a monoclonal antibody for human CD20, was shown to be safe in patients with primary biliary cirrhosis (PBC) who had an incomplete response to the standard ursodeoxycholic acid (UDCA) therapy, also known as Ursodiol. Study details available in the February issue of Hepatology a journal published by Wiley-Blackwell on behalf of the American Association for the Study of Liver Diseases, report that rituximab was successful in reducing the level of alkaline phosphatase (ALP) - a protein used to measure liver injury... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 6, 2012 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

The Benefits Of Novel PSA Velocity Risk Count Testing For Prostate Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A new study by NYU Langone Medical Center and Northwestern University Feinberg School of Medicine shows novel PSA velocity (PSAV) risk count testing may provide a more effective way for physicians to screen men for clinically significant prostate cancer. The new study, published online by the British Journal of Urology Internationa shows the benefits of tracking a man's PSA levels over time to help doctors more accurately assess his risk of life-threatening prostate cancer... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 6, 2012 Category: Consumer Health News Tags: Prostate / Prostate Cancer Source Type: news

Home-based Dialysis For Kidney Failure Gaining Popularity In Developing Countriesemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Home-based dialysis treatments are on the rise in both the developing and developed worlds, but developed countries appear to be turning to them less often, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The findings, which provide a global snapshot of dialysis use among patients with kidney failure, may impact future business and research innovations. Dialysis treatments for kidney failure come in two forms: peritoneal dialysis is usually done at home, while hemodialysis is predominantly clinic-based... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 6, 2012 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

Herb-Drug Interaction of 50 Chinese Herbal Medicines on CYP3A4 Activity in Vitro and in Vivo.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study provides evidence of possible herb-drug interactions involved with certain single herbs. PMID: 22298448 [PubMed - in process] (Source: The American Journal of Chinese Medicine)
Source: The American Journal of Chinese Medicine - February 5, 2012 Category: Complementary Medicine Authors: Pao LH, Hu OY, Fan HY, Lin CC, Liu LC, Huang PW Tags: Am J Chin Med Source Type: research

2 Hz Electro-Acupuncture at Yinlingquan (SP9) and Ququan (LR8) Acupoints Induces Changes in Blood Flow in the Liver and Spleen.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract According to the principles of traditional Chinese medicine, channels and collaterals within the body provide pathways through which qi and blood travel, and each channel or collateral is linked with a specific organ. The Yinlingquan (spleen 9, SP9) and Ququan (liver 8, LR8) acupoints represent the sea points of the spleen and liver meridians, respectively, from which qi and blood flow into their specific visceral organs. The purpose of this study was to investigate the changes in blood flow/perfusion in the liver and spleen resulting from the application of 2 Hz electro-acupuncture (EA) to the Yinlingquan...
Source: The American Journal of Chinese Medicine - February 5, 2012 Category: Complementary Medicine Authors: Chou WC, Liu HJ, Lin YW, Cheng CY, Li TC, Tang NY, Hsieh CL Tags: Am J Chin Med Source Type: research

Antioxidant and Anti-Inflammatory Effects of a Hypoglycemic Fraction from Cucurbita ficifolia Bouché in Streptozotocin-Induced Diabetes Mice.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract Type 2 diabetes is characterized by oxidative stress and a chronic low-grade inflammatory state, which also play roles in the pathogenesis of this disease and the accompanying vascular complications by increasing the production of free radicals and pro-inflammatory cytokines. Cucurbita ficifolia Bouché (C. ficifolia) is an edible Mexican plant whose hypoglycemic activity has been demonstrated in several experimental and clinical conditions. Recently, D-chiro-inositol has been proposed as the compound responsible for the hypoglycemic effects; however, the antioxidant and anti-inflammatory potential of this...
Source: The American Journal of Chinese Medicine - February 5, 2012 Category: Complementary Medicine Authors: Roman-Ramos R, Almanza-Perez JC, Fortis-Barrera A, Angeles-Mejia S, Banderas-Dorantes TR, Zamilpa-Alvarez A, Diaz-Flores M, Jasso I, Blancas-Flores G, Gomez J, Alarcon-Aguilar FJ Tags: Am J Chin Med Source Type: research

Personalized treatment of colorectal cancer.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract In the last 15 years, significant progress in the management of colorectal cancer (CRC) has been achieved with several new agents licensed extending median overall survival for stage IV disease to about 2 years. Treatment of CRC is stage-specific, multidisciplinary, and based on patient and tumor characteristics. Although especially early stages (0-III, according to Union for International Cancer Control) are treated with curative intent, patients with limited stage IV disease (liver and/or lung or localized peritoneal metastases) might still be curable in a multimodality approach including surgery, periop...
Source: Onkologie - February 5, 2012 Category: Cancer & Oncology Authors: Arnold D, Stein A Tags: Onkologie Source Type: research

What Are the Major Diseases Involving Copper Metabolism?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Discussion Nutritional problems can occur in all parts of the world and in all socioeconomic strata. Caloric and/or protein inadequacy unfortunately plagues too many people because of inadequate supplies or availability. Supplemental food programs around the world attempt to provide appropriate nutrition, but can be stymied because of war, political instability, economic instability and many other social factors. The most common specific nutrient deficiencies are iron and Vitamin D deficiencies. Minerals important for essential nutrition include copper, iodine, selenium and zinc. A typical mixed diet usually provides enou...
Source: PediatricEducation.org - February 5, 2012 Category: Pediatrics Authors: Donna M. D'Alessandro, M.D. Tags: Uncategorized Source Type: news

Evaluation of hepatoprotective activity of aqueous and ethanolic extract of Oxalis corniculata against intoxication of thioacetamide induced ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
The present study was carried out to evaluate the hepatoprotective activity of aqueous and ethanolic leaves extracts of Oxalis corniculata L., Oxalidaceae, against thioacetamide-induced hepatotoxicity. Hepatotoxicity was induced in Wistar rats of either sex by subcutaneous injection of thioacetamide. An aqueous and ethanolic extract of aerial parts of O. corniculata (200 and 400 mg/kg/day) were evaluated. Oral administration of O. corniculata aqueous and ethanolic leaves extract at 400 mg/kg resulted in a significant reduction in SGOT (146.42±2.54 and 136.75±1.37 IU/L respectively), SGPT (81.96±3.15 and 72.05±2.33 IU/L...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research

Effect of a plant origin drug on the biodistribution of 99mTc-DTPA in Wistar albino ratsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In recent years all over the world, medicinal plants are used quite a lot but side effects of biological and chemical contents and radiopharmaceutical interactions for each consumer in question aren't entirely well-known. The studies of plant origin drug interaction with radiopharmaceuticals are highly relevant and desired. One of them is passiflora syrup (Passiflora incarnata L., Passifloraceae) which is widely used for depression, insomnia, anxiety and menopause period. The aim of current study is to evaluate possible effects of passiflora syrup on the biodistribution of 99mTc-DTPA and its blood cells uptake. DTPA was la...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research

Polyphenols of Mangifera indica modulate arsenite-induced cytotoxicity in a human proximal tubule cell lineemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Inorganic arsenic is an ubiquitous environmental contaminant able to cause severe pathologies in humans, including kidney disorders. The possible protective effects of Mangifera indica L., Anacardiaceae, stem bark extract (MSBE) and some mango phenols on the cytotoxicity of arsenite (AsIII) in the proximal tubule cell line HK-2 was investigated. In cells cultured for 24 h in presence of AsIII, a dose-dependent loss of cell viability occurred that was significantly alleviated by MSBE, followed by gallic acid, catechin and mangiferin. Mangiferin complexed with Fe+++ proved more efficacious than mangiferin alone. MSBE and pur...
Source: Revista Brasileira de Farmacognosia - February 5, 2012 Category: Drugs & Pharmacology Source Type: research

Ivermectin: Liver dysfunction in an elderly patient: case reportemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
(Source: Reactions)
Source: Reactions - February 5, 2012 Category: Drugs & Pharmacology Tags: Short communication Source Type: research

Surfactant protein D inhibits lipopolysaccharide-induced monocyte chemoattractant protein-1 expression in human renal tubular epithelial cells: implication for tubulointerstitial fibrosis.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract Surfactant protein D (SP-D), a member of the C-type lectin (collectin) protein family, plays a critical role in innate host defence against various microbial pathogens and in the modulation of inflammatory responses in the lung. However, little is known about its expression and biological function in the kidney. In this work, we studied SP-D expression in human kidney and cultured human renal proximal tubular epithelial cells (HK-2), and examined the effect of SP-D on proinflammatory cytokine production after lipopolysaccharide (LPS) stimulus. We observed the expression of both SP-D mRNA and protein in hum...
Source: Clinical and Developmental Immunology - February 5, 2012 Category: Allergy & Immunology Authors: Hu F, Liang W, Ren Z, Wang G, Ding G Tags: Clin Exp Immunol Source Type: research

Induction of elastin expression in vascular endothelial cells relates to hepatoportal sclerosis in idiopathic portal hypertension: possible link to serum anti-endothelial cell antibodies.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study was performed to clarify the mechanism of elastic fibre deposition in the peripheral portal tracts of IPH liver in relation to serum anti-endothelial cell antibodies (AECA). In-vitro experiments were performed using human dermal microvascular endothelial cells (HMVEC) and patients' sera. The presence of serum AECA was assayed by a cell-based enzyme-linked immunosorbent assay (ELISA) using HMVEC. Immunohistochemical analysis of elastin was performed using liver tissue sections of IPH patients. IPH sera contained one or more AECA that could bind to the vascular endothelial cells of the peripheral portal tracts of ...
Source: Clinical and Developmental Immunology - February 5, 2012 Category: Allergy & Immunology Authors: Sato Y, Ren XS, Harada K, Sasaki M, Morikawa H, Shiomi S, Honda M, Kaneko S, Nakanuma Y Tags: Clin Exp Immunol Source Type: research

Advances and New Research in the Treatment of Kidney Canceremail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
CancerNetwork speaks with Dr. Michael Atkins, who has extensive clinical experience in kidney cancer and development of various new treatments, and is presenting this weekend during the renal cancer translational science session at the American Society of Clinical Oncology 2012 Genitourinary Cancers Symposium. (Source: Cancer Network)
Source: Cancer Network - February 5, 2012 Category: Cancer & Oncology Source Type: news

Population‐based survival for childhood cancer patients diagnosed during 2002–2005 in Shanghai, Chinaemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
ConclusionsThe survival rate for children aged 0–14 diagnosed with cancer in Shanghai during 2002–2005 was at the medium level. There was a substantial survival difference from childhood cancers between Shanghai and specific developed countries. Pediatr Blood Cancer © 2012 Wiley Periodicals, Inc. (Source: Pediatric Blood and Cancer)
Source: Pediatric Blood and Cancer - February 5, 2012 Category: Cancer & Oncology Authors: Ping‐ping BaoYing ZhengChun‐xiao WuPeng PengYang‐ming GongZhe‐zhou HuangWu Fan Tags: Research Article Source Type: research

Autophagy: A cyto-protective mechanism which prevents primary human hepatocyte apoptosis during oxidative stress.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract The role of autophagy in the response of human hepatocytes to oxidative stress remains unknown. Understanding this process may have important implications for the understanding of basic liver epithelial cell biology and the responses of hepatocytes during liver disease. To address this we isolated primary hepatocytes from human liver tissue and exposed them ex vivo to hypoxia and hypoxia-reoxygenation (H-R). We showed that oxidative stress increased hepatocyte autophagy in a reactive oxygen species (ROS) and class III PtdIns3K-dependent manner. Specifically, mitochondrial ROS and NADPH oxidase were found t...
Source: Autophagy - February 5, 2012 Category: Cytology Authors: Bhogal RH, Weston CJ, Curbishley SM, Adams DH, Afford SC Tags: Autophagy Source Type: research

New Liver Cancer Treatment: Y-90email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
A new strategy for treating liver cancer involves radiation, microscopic beads and an isotope known as Y-90. To learn how Y-90 microsphere radioembolization attacks liver tumors, Sound Medicine's Steve Bogdewic, PhD, meets with Indiana University liver cancer specialists Mary Maluccio, MD, and Matthew Johnson, MD. Drs. Maluccio and Johnson are on faculty at the IU School of Medicine and are re.... (Source: Sound Medicine)
Source: Sound Medicine - February 5, 2012 Category: Global & Universal Authors: Sound Medicine Source Type: news

Comparability of cancer identification among death registry, cancer registry and hospital discharge registryemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
In conclusion, some 10% of cancer deaths had no cancer records in CR or in HDR, and 3.4% were missing in both sources. The identification rate depended on tumor site, age at death, and, to some extent, death outside hospital. © 2012 Wiley‐Liss, Inc. (Source: International Journal of Cancer)
Source: International Journal of Cancer - February 5, 2012 Category: Cancer & Oncology Authors: Jianguang JiKristina SundquistJan SundquistKari Hemminki Tags: Epidemiology Source Type: research

Exelixis' Cabozantinib Shows Encouraging Activityemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
14.7 months median progression free survival; 28% confirmed partial response rate & 72% disease control rate at week 16. 02/05/2012 (Source: Kidney Cancer Association)
Source: Kidney Cancer Association - February 4, 2012 Category: Cancer & Oncology Source Type: news

For Kidney Disease Patients, Goals For Blood Pressure May Be Unrealisticemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
An upward revision of the blood pressure numbers used to identify risk of end-stage renal disease (ESRD) might actually help doctors provide better care for their patients, said the authors of a study in patients with chronic kidney disease (CKD). The researchers found that systolic blood pressure - the "upper number" in a blood pressure reading - was the key variable. Current guidelines call for CKD patients to maintain a systolic pressure of 130/80 or lower in order to prevent ESRD, which is complete or almost complete kidney failure, leading to dialysis, kidney transplant, or death... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 4, 2012 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

In Preadolescence, Sleep Deprivation Tied To Increased Nighttime Urinationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Nighttime visits to the bathroom are generally associated with being pregnant or having an enlarged prostate, but the problem can affect youngsters, too. A new study sheds light on why some children may need to urinate more often during the rest cycle. Danish researchers have found that sleep deprivation causes healthy children, between the ages of eight and twelve, to urinate significantly more frequently, excrete more sodium in their urine, have altered regulation of the hormones important for excretion, and have higher blood pressure and heart rates... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 4, 2012 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news

MS/MS library facilitated MRM quantification of native peptides prepared by denaturing ultrafiltrationemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Naturally occurring native peptides provide important information about physiological states of an organism and its changes in disease conditions but protocols and methods for assessing their abundance are not well-developed. In this paper, we describe a simple procedure for the quantification of non-tryptic peptides in body fluids. The workflow includes an enrichment step followed by two-dimensional fractionation of native peptides and MS/MS data management facilitating the design and validation of LC- MRM MS assays. The added value of the workflow is demonstrated in the development of a triplex LC-MRM MS assay used for q...
Source: BioMed Central - February 4, 2012 Category: Journals (General) Authors: Juraj LencoRenny LanNathan EdwardsRadoslav Goldman Source Type: research

Effect of ethanol injection on cavitation and heating of tissues exposed to high-intensity focused ultrasound.email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
This study opens up the possibility of improved tumor ablation therapy via a combination of percutaneous ethanol injection and high-intensity focused ultrasound. PMID: 22290554 [PubMed - in process] (Source: Physics in Medicine and Biology)
Source: Physics in Medicine and Biology - February 3, 2012 Category: Physics Authors: Chen C, Liu Y, Maruvada S, Myers M, Khismatullin D Tags: Phys Med Biol Source Type: research

Serum IL-33 Levels Are Associated with Liver Damage in Patients with Chronic Hepatitis Bemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Journal of Interferon & Cytokine Research , Vol. 0, No. 0. (Source: Journal of Interferon)
Source: Journal of Interferon - February 3, 2012 Category: Research Tags: article Source Type: research

Urethral Catheterization Facilitates Preradiation Fiducial Marker Placement in Postprostatectomy Patientsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Journal of Endourology , Vol. 0, No. 0. (Source: Journal of Endourology)
Source: Journal of Endourology - February 3, 2012 Category: Urology & Nephrology Tags: article Source Type: research

Abercrombie to sign organ transplant funding bill into lawemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Hawaii lawmakers on Friday passed legislation for about $1.8 million in emergency funds for kidney and liver transplants in the state. Gov. Neil Abercrombie plans to sign House Bill 608 into law on Saturday at The Queen's Medical Center. The law will appropriate emergency funds, subject to private matching funds, for the transplants, as well as to support a chronic kidney disease management program. Hawaii was left without an organ transplant center after the closure last month of Hawaii Medical Center East, which ran the state's only organ transplant program before it stopped taking patients in December... (Source: biz...
Source: bizjournals.com Health Care:Hospitals headlines - February 3, 2012 Category: Hospital Management Source Type: research

Chronic Kidney Disease and End-Stage Renal Disease Predict Higher Risk of Mortality in Patients with Primary Upper Gastrointestinal Bleedingemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Am J Nephrol 2012;35:216–224 (DOI:10.1159/000336107) (Source: Karger Publishers)
Source: Karger Publishers - February 3, 2012 Category: Cancer & Oncology Source Type: research

Hepatitis Research May Benefit From Stem Cellsemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Hepatitis C is a viral disease that leads to inflammation and organ failure. However, researchers are puzzled as to why some individuals are very susceptible to the disease, while others are not. Researchers believe they could find out how genetic variations produce these different responses by investigating liver cells from different individuals in the lab. However, liver cells are hard to obtain and extremely challenging to grow in a lab dish as they often lose their normal function and structure when removed from the body... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 3, 2012 Category: Consumer Health News Tags: Liver Disease / Hepatitis Source Type: news

Six-Organ Transplant Girl Goes Home Todayemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
After 100 days in hospital and undergoing a complicated 6-organ transplant, 9-year-old Alannah Shevenell, from Maine, leaves Boston Children's Hospital today and goes home. Alannah has been treated for a rare form of cancer; an inflammatory myofibroblastic tumor continued to grow after all possible treatments failed, and was compromising her internal organs. A team of surgeons, led by Dr. Heung Bae Kim, the hospital's Pediatric Transplant Center director, performed the transplant procedure of Alannah's liver, spleen, pancreas, stomach, small intestine and esophagus... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - February 3, 2012 Category: Consumer Health News Tags: Transplants / Organ Donations Source Type: news

Are intravenous injections of contrast media really less nephrotoxic than intra-arterial injections?email this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Abstract  We oppose the opinion that the intra-arterial administration of iodine-based contrast media (CM) appears to pose a greater risk of contrast medium-induced nephropathy (CIN) than intravenous administration since 1) in intra-arterial coronary procedures and most other intra-arterial angiographic examinations, CM injections are also intravenous relative to the kidneys, 2) there is a lack of comparative trials studying the risk of CIN between intra-arterial and intravenous procedures with matched risk factors and CM doses, 3) a bias selection of patients with fewer risk factors may explain the seemingly...
Source: European Radiology - February 3, 2012 Category: Radiology Tags: European Radiology Source Type: research

The Empowered Patientemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Members of the Kidney Cancer Association are attending the 2012 Genitourinary Cancers Symposium in San Francisco this week.  Our Medical & Scientific Steering Committee meets here and we convened the first meeting of our new Neoadjuvant Group.  We are currently studying the formation of a Kidney Cancer Association Clinical Trials Consortium that may address specific unmet needs in research. We encourage patients and their family members to invest the time necessary to evaluate information from this imporant Symposium that is freely available online from ASCO.  If you have specific questions, we'l...
Source: Kidney Cancer Association - February 3, 2012 Category: Cancer & Oncology Source Type: news

Maine girl home after 6-organ transplantemail this articleEmail this article to a colleague. save this article to My ClippingsSave this article to My Clippings. discuss this articleDiscuss or comment on this article.
Alannah Shevenell, 9, needed new stomach, liver, spleen, small intestine, pancreas, esophagus after all were squashed by tumor (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - February 3, 2012 Category: Consumer Health News Source Type: news