Veterinary Research Top 20 This is an OPML file. It can be used to export all the MedWorm RSS feeds on this topic into your personal RSS reader (usually you have to save this file to your own computer before clicking on an Import OPML command in your own feed reader to upload the file which will then import all the feeds) or it can be used by webmasters to integrate MedWorm feeds with their own website. This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader, such as GoogleReader, or to display this data on your own website or blog. Subscribe to this data using MyMedWorm.Subscribe to this data using GoogleReader.Subscribe to this data using Bloglines.Subscribe to this data using MyYahoo.

This page shows you the 20 most read items in the past 30 days within this specialty in the MedWorm directory.

Stem cell therapy in veterinary dermatology.
Abstract Background - Adult stem cells come from many sources and have the capacity to differentiate into many cell types, including those of the skin. The most commonly studied stem cells are those termed mesenchymal stem cells (MSCs), which are easily isolated from bone marrow and adipose tissue. Mesenchymal stem cells are known to produce a wide array of cytokines that modulate the regeneration process. The ease of collection, propagation and use of these MSCs in therapy of traumatic, ischaemic and immune-mediated skin conditions is emerging. Approach and evidence - In traumatic and ischaemic skin damage, ...
Source: Veterinary Dermatology - January 28, 2013 Category: Veterinary Research Authors: Harman RJ Tags: Vet Dermatol Source Type: research

Plasma drug concentrations and clinical effects of a peripheral alpha‐2‐adrenoceptor antagonist, MK‐467, in horses sedated with detomidine
Conclusions and clinical relevanceMK‐467 prevented detomidine induced bradycardia and intestinal hypomotility. MK‐467 did not affect the clinical quality of detomidine‐induced sedation, but the duration of the effect was reduced, which may have been caused by the effects of MK‐467 on the plasma concentration of detomidine. MK‐467 may be useful clinically in the prevention of certain peripheral side effects of detomidine in horses. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - January 31, 2013 Category: Veterinary Research Authors: Mari H Vainionpää, Marja R Raekallio, Soile AE Pakkanen, Ville Ranta‐Panula, Valtteri M Rinne, Mika Scheinin, Outi M Vainio Tags: Research Paper Source Type: research

Temporary tracheostomy tubes complications
Tracheostomy tubes are used to provide a temporary patent airway in cases with upper respiratory tract obstruction; to allow conscious ventilation when neurological or respiratory function is compromised; to improve surgical access to the mouth or pharynx during anesthesia; or to allow repeated access to diseased lungs. Complications of tracheostomy are reported to occur in 43 to 87% of dogs and cats with either tube or permanent tracheostomy during hospitalization. The reported mortality rate of either tube or permanent tracheostomy in dogs and cats is up to 39%, caused by asphyxiation after tube obstruction or dislodgeme...
Source: Advances in Small Animal Medicine and Surgery - February 1, 2013 Category: Veterinary Research Tags: Respiratory Medicine Source Type: research

Measurement of respiratory system compliance and respiratory system resistance in healthy dogs undergoing general anaesthesia for elective orthopaedic procedures
Conclusion and clinical relevance Body weight was linearly related to Crs while Rrs has an inverse linear relationship with body weight in mechanically ventilated dogs. The derived values of Crs and Rrs may be used for monitoring of lung function and ventilation in healthy dogs under anaesthesia. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - February 23, 2013 Category: Veterinary Research Authors: Carl A Bradbrook, Louise Clark, Alexandra HA Dugdale, John Burford, Martina Mosing Tags: RESEARCH PAPER Source Type: research

Microbiologic and Cytologic Assessment of Bronchoalveolar Lavage Fluid from Dogs with Lower Respiratory Tract Infection: 105 Cases (2001–2011)
Conclusions and Clinical ImportanceConfirmation of lower respiratory tract infection in dogs is challenging and organisms can be isolated from dogs in which bacteria are not detected on cytologic examination. (Source: Journal of Veterinary Internal Medicine)
Source: Journal of Veterinary Internal Medicine - January 30, 2013 Category: Veterinary Research Authors: L.R. Johnson, E.V. Queen, W. Vernau, J.E. Sykes, B.A. Byrne Tags: Standard Article Source Type: research

Effects of inspired oxygen concentration on ventilation, ventilatory rhythm, and gas exchange in isoflurane-anesthetized horses.
Conclusion and Clinical Relevance-Use of 50% inspired oxygen did not improve the ventilatory rhythm or gas exchange and increased the risk of hypoxemia in spontaneously breathing horses during isoflurane anesthesia. Use of both inspired oxygen fractions requires adequate monitoring and the capacity for mechanical ventilation. PMID: 23363340 [PubMed - in process] (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - February 1, 2013 Category: Veterinary Research Authors: Crumley MN, McMurphy RM, Hodgson DS, Kreider SE Tags: Am J Vet Res Source Type: research

Evaluation of the efficacy and safety of single administration of 4.7-mg deslorelin acetate implants on egg production and plasma sex hormones in Japanese quail (Coturnix coturnix japonica).
Conclusions and Clinical Relevance-4.7-mg deslorelin acetate implants reversibly decreased egg laying for approximately 70 days in most of the Japanese quail evaluated. Further studies evaluating implants containing different concentrations of the drug are needed in quail and other avian species. PMID: 23363360 [PubMed - in process] (Source: American Journal of Veterinary Research)
Source: American Journal of Veterinary Research - February 1, 2013 Category: Veterinary Research Authors: Petritz OA, Sanchez-Migallon Guzman D, Paul-Murphy J, Fecteau K, Mete A, Kass PH, Hawkins MG Tags: Am J Vet Res Source Type: research

Advances in the management of skin cancer.
Abstract Skin cancer is one of the most commonly diagnosed cancers in the world today in both humans and our pet population. Advances in molecular techniques are now affording us an opportunity to develop therapeutics targeted at specific cancer-related cellular pathways. However, despite progress in conventional treatments, such as chemotherapy and radiation, and the new targeted therapies, some cancers, such as melanoma and cutaneous lymphoma, continue to cause significant mortality and morbidity. This short synopsis is not complete but is aimed at providing an insight into current advanced treatments and horizon...
Source: Veterinary Dermatology - January 28, 2013 Category: Veterinary Research Authors: Martin PD, Argyle DJ Tags: Vet Dermatol Source Type: research

Effect of maropitant, a neurokinin‐1 receptor antagonist, on the minimum alveolar concentration of sevoflurane during stimulation of the ovarian ligament in cats
Conclusion and clinical relevanceThe ovarian ligament stimulation model is suitable to determine MAC during visceral stimulation in cats. Maropitant decreased the anesthetic requirements during visceral ovarian and ovarian ligament stimulation in cats. Maropitant (1 mg kg−1) decreases MAC by 15%; a higher dose had no additional effect. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - February 13, 2013 Category: Veterinary Research Authors: Sirirat Niyom, Pedro Boscan, David C Twedt, Eric Monnet, Jens C Eickhoff Tags: Research Paper Source Type: research

Non‐fatal high‐rate iatrogenic venous air embolism in a cat
(Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - February 13, 2013 Category: Veterinary Research Authors: Virginie Boitout, Stephan P Mahler Tags: Letter to the Editor Source Type: research

Influence of detomidine and xylazine on spleen dimensions and on splenic response to epinephrine infusion in healthy adult horses
ConclusionsDetomidine administration was followed by a sonographically detectable increase of splenic length. Neither detomidine nor xylazine interfered with the ability of the spleen to contract following subsequent administration of an epinephrine infusion given one hour later. Clinical relevancePrevious sedation with alpha‐2 agonists does not preclude the efficiency of epinephrine as a medical treatment of left dorsal displacement of the large colon, but further investigations are required with other drug doses and different time intervals between administrations. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - February 12, 2013 Category: Veterinary Research Authors: Valérie Deniau, Marianne Depecker, Céline Bizon‐Mercier, Anne Couroucé‐Malblanc Tags: Research Paper Source Type: research

Assessment of the variation in American Society of Anaesthesiologists Physical Status Classification assignment in small animal anaesthesia
Conclusions and clinical relevanceThis study suggests major discrepancies can occur between observers given identical information when using the ASA‐PSC to categorise health status in compromised small animal patients. The significant potential for interobserver variability in classification allocation should be borne in mind when the ASA‐PSC is used for clinical, scientific and statistical purposes. (Source: Veterinary Anaesthesia and Analgesia)
Source: Veterinary Anaesthesia and Analgesia - February 12, 2013 Category: Veterinary Research Authors: Matthew McMillan, Jacqueline Brearley Tags: Research Paper Source Type: research

Small intestine histomorphometry of beef cattle with divergent feed efficiency
The objective was to verify the potential histomorphological differences in the small intestine of animals with divergent feed efficiency. Methods: From a population of 45 feedlot steers, 12 were selected with low-RFI (superior feed efficiency) and 12 with high-RFI (inferior feed efficiency) at the end of the finishing period. The animals were processed at 13.79 +/- 1.21 months of age. Within 1.5 h of slaughter the gastrointestinal tract was collected and segments from duodenum and ileum were harvested. Tissue fragments were processed, sectioned and stained with hematoxylin and eosin. Photomicroscopy images were taken unde...
Source: Acta Veterinaria Scandinavica - February 5, 2013 Category: Veterinary Research Authors: Yuri MontanholiAnanda FontouraKendall SwansonBrenda CoomberShigeto YamashiroStephen Miller Source Type: research

Interleukin-6, vascular endothelial growth factor and transforming growth factor beta 1 in canine steroid responsive meningitis-arteritis
Conclusions: Our results suggest that these three signalling proteins are biomarkers of disease activity in SRMA. VEGF might play an important role in the development of a systemic arteritis. TGF-beta1 is considered to be involved in the excessive IgA production, while IL-6 in the pleocytosis. The combined intrathecal increase of TGF-beta1 and IL-6 detected in SRMA could possibly force CD4 progenitors to differentiate towards the newly described Th17 lymphocyte subset and enhance the autoimmune response. (Source: BMC Veterinary Research - Latest articles)
Source: BMC Veterinary Research - Latest articles - February 4, 2013 Category: Veterinary Research Authors: Arianna MaioliniMeike OttenMarion Hewicker-TrautweinRegina CarlsonAndrea Tipold Source Type: research

Curettage and diathermy: a treatment for feline nasal planum actinic dysplasia and superficial squamous cell carcinoma
This study suggests that curettage and diathermy is an effective treatment for feline actinic dysplasia and for superficial squamous cell carcinoma involving less than 50% of the nasal planum. Curettage and diathermy is an easily mastered technique, requiring minimal equipment. (Source: The Journal of Small Animal Practice)
Source: The Journal of Small Animal Practice - February 1, 2013 Category: Veterinary Research Authors: R. H. Jarrett, E. J. Norman, I. R. Gibson, P. Jarrett Tags: PAPER Source Type: research

Comparison of Two Surgical Site Protocols for Cattle in a Field Setting
ConclusionsAn abbreviated preoperative protocol using nonsterile reusable material can be as effective as a standard protocol using sterile one‐use brush in reducing skin microflora and preventing surgical wound infection. (Source: Veterinary Surgery)
Source: Veterinary Surgery - February 1, 2013 Category: Veterinary Research Authors: Clara Bourel, Sébastien Buczinski, André Desrochers, Denis Harvey Tags: Original Article: Clinical Source Type: research

In Vivo Assessment of Absorbable Knotless Barbed Suture for Single Layer Gastrotomy and Enterotomy Closure
ConclusionThe barbed device compared favorably with monofilament suture for gastrotomy and enterotomy (small intestine, colon) closure. Results demonstrate comparable burst strengths between monofilament suture and the barbed device. Closure time was significantly reduced in jejunum closure using the barbed device. (Source: Veterinary Surgery)
Source: Veterinary Surgery - February 1, 2013 Category: Veterinary Research Authors: Nicole P. Ehrhart, Kristina Kaminskaya, Jeffrey A. Miller, Jeff F. Zaruby Tags: Original Article: Research Source Type: research

Malignant peripheral nerve sheath tumor as a cause of chronic cardiac insufficiency in cattle
Chronic cardiac insufficiency was associated with a malignant peripheral nerve sheath tumor in a cow. An eight-year-old cow developed a progressive condition (over a period of three months) characterized by an enhanced abdominal volume, reluctance to move, a positive jugular pulse, watery diarrhea and death. At necropsy, moderate subcutaneous edema and an enhanced hepatic lobular pattern were observed. A 23x20x11 cm firm, grayish-white mass adhered to and infiltrated the right atrium. Multiple firm, yellowish-white nodules of 0.5 to 12 cm in diameter were diffusely scattered in the epicardium and parietal pericardium. Hist...
Source: Acta Veterinaria Scandinavica - January 31, 2013 Category: Veterinary Research Authors: Saulo PavariniDanilo GomesMarcele BandinelliFlademir WoutersLuciana SonneDavid DriemeierCláudio Farias da Cruz Source Type: research

Fenugreek seeds, a hepatoprotector forage crop against chronic AlCl3 toxicity
Conclusion: This study highlighted the hepatotoxicity of AlCl3 through biochemical and histological parameters in one hand and the hepatoprotective role of fenugreek seeds on the other hand. Thus this work could be a pilot study which will encourage farmers to use fenugreek seeds as a detoxifying diet supplement for domestic animals. (Source: BMC Veterinary Research - Latest articles)
Source: BMC Veterinary Research - Latest articles - January 31, 2013 Category: Veterinary Research Authors: Yosra Belaïd-NouiraHayfa BakhtaZohra HaouasImen Flehi-SlimFadoua NeffatiMohamed Fadhel NajjarHassen Ben Cheikh Source Type: research

Masitinib reverses doxorubicin resistance in canine lymphoid cells by inhibiting the function of P‐glycoprotein
Overexpression of ABC‐transporters including Pgp, MRP1, and BCRP has been associated with multidrug resistance (MDR) in both human and canine oncology. Therapeutic interventions to reverse MDR are limited, but include multidrug protocols and the temporary concomitant use of inhibitors of ABC‐transporters. Recently, the use of tyrosine kinase inhibitors has been proposed to overcome MDR in human oncology. One of the tyrosine kinase inhibitors, masitinib, is licensed for veterinary use in the treatment of canine mast cell tumors. Therefore, this study aimed to assess the potential of masitinib to revert MDR in canine mal...
Source: Journal of Veterinary Pharmacology and Therapeutics - February 1, 2013 Category: Veterinary Research Authors: M. Zandvliet, E. Teske, T. Chapuis, J. Fink‐Gremmels, J. A. Schrickx Tags: Scientific Paper Source Type: research