MedWorm: Acne

SAPHO syndrome: is a range of pathogen-associated rheumatic diseases extended?

Arthritis Research and Therapy — Thu, 05 Nov 2009 00:00:00 +0100

SAPHO syndrome, representing a constellation of synovitis, acne, palmo-plantar pustulosis, hyperostosis and osteitis, is now recognized as a distinct medical entity, a reactive infectious osteitis. Genetic, immunological and bacterial mechanisms are implicated in the development of the disease. Diagnostic problems may rise due to non complete manifestations of SAPHO: acne and arthritis, or acne and anterior wall osteitis with an unclear pustulosis history. The interventional study of Assman et al. is a significant addition to a long range of publications, showing an association of SAPHO with P. acnes. Randomized control studies are needed to confirm the effects of antibiotic therapy. (Source: Arthritis Research and Therapy)

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Acne: Causes, treatment and prevention

MayoClinic.com Full Feed — Wed, 04 Nov 2009 02:45:01 +0100

Acne — Comprehensive overview covers causes, acne treatments, including adult acne treatments, and prevention. Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)

Too old for acne? At 30, Rebecca thought she was past the age for spots

the Mail online | Health — Tue, 03 Nov 2009 00:19:00 +0100

Adults acne is a growing problem. Occurring mostly in women, one recent study estimated that 14 per cent of those aged between 26 and 44 in the UK suffer from acne. (Source: the Mail online | Health)

Skin Tightening Effect Using Fractional Laser Treatment: I. A Randomized Half-Side Pilot Study on Faces of Patients with Acne

Dermatologic Surgery — Tue, 03 Nov 2009 00:00:00 +0100

Fractional laser resurfacing is a new procedure for skin rejuvenation. To assess the skin remodeling effect of fractional laser treatment. Twelve Asian patients with acne were irradiated using a fractional 1,540-nm erbium glass laser on a random half of the face twice with a 4-week interval. The faces were contoured on the treated side of most patients. Statistical analyses of the facial images showed that the skin tightening effect was significant 4 weeks after the first and second irradiation (p (Source: Dermatologic Surgery)

Fractional CO2 laser: a novel therapeutic device upon photobiomodulation of tissue remodeling and cytokine pathway of tissue repair

Dermatologic Therapy — Tue, 03 Nov 2009 00:00:00 +0100

Minimally ablative fractional laser devices have gained acceptance as a preferred method for skin resurfacing. Notable improvements in facial rhytides, photodamage, acne scarring, and skin laxity have been reported. The aim of the present work was to compare how different CO2 laser fluences, by modulating the secretory pathway of cytokines, are able to influence the wound-healing process, and how these fluences are associated with different clinical results. Eighteen patients, all with photodamaged skin, were treated using a fractional CO2 laser (SmartXide DOT, Deka M.E.L.A., Florence, Italy) with varying laser fluences (2.07, 2.77, and 4.15 J/cm2). An immunocytochemical study was performed at defined end points in order to obtain information about specific cytokines of the microenvironmen...

Effaclar Acne Spot Treatment

Skin and Allergy News — Sun, 01 Nov 2009 00:00:00 +0100

La Roche-Posay's Effaclar AI Intensive Acne Spot Treatment is available to reduce stubborn and inflammatory acne in as few as 3 days. The formulation includes a 5.5% concentration of micronized benzoyl peroxide to clear inflammatory acne, as well as 0.4% LHA (lipohydroxy acid), which is a lipophilic derivative of salicylic acid that micro-exfoliates the skin and stimulates cell renewal to help even the skin tone, including residual skin marking. The product is oil free and noncomedogenic, and has been tested on sensitive skin. (Source: Skin and Allergy News)

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Personalized OTC Acne Care

Skin and Allergy News — Sun, 01 Nov 2009 00:00:00 +0100

Neutrogena's Skin ID regimen is available to treat and help prevent acne. The three-product, over-the-counter system is offered as an alternative to antibiotics for those who are concerned about building resistance to antibiotic treatments. Customers can complete an online skin evaluation that will direct them to a gel cleanser, an acne treatment, and a moisturizer “personalized” to fit their skin condition. The regimen includes salicylic acid, benzoyl peroxide, and a proprietary MicroClear technology to deliver the medication deep into pores; the system retails for about $40. (Source: Skin and Allergy News)

Sun Defense Kit for Acne-Prone Skin

Skin and Allergy News — Sun, 01 Nov 2009 00:00:00 +0100

Acne patients may be at increased risk for sun sensitivity and skin damage, depending on their treatment regimen. The Avidoxy DK defence kit offers products that provide sun protection for acne suffers without exacerbating their condition. The kit consists of 100-mg doxycycline tablets (available by prescription only) to help destroy acne-causing bacteria, plus two free products: defence acne wash and defence solare SPF 30. The acne wash contains 2% salicylic acid to promote cleansing and exfoliation, and it is oil-free and alcohol-free. The defence solare SPF is an oil-free, noncomedogenic, moisturizing sunblock that contains antioxidants and zinc oxide to provide broad-spectrum sun protection for acne-prone skin. (Source: Skin and Allergy News)

Benzoyl peroxide and adapalene fixed combination: a novel agent for acne.

The British Journal of Dermatology — Thu, 29 Oct 2009 15:18:25 +0100

Authors: Layton AM, Eady EA PMID: 19857206 [PubMed - in process] (Source: The British Journal of Dermatology)

ACG: Acne Drug Tied to IBD (CME/CE)

MedPage Today Gastroenterology — Thu, 29 Oct 2009 13:00:25 +0100

SAN DIEGO (MedPage Today) -- Use of the acne medication isotretinoin (Accutane) is associated with an increased risk of inflammatory bowel disease, researchers said here. (Source: MedPage Today Gastroenterology)

Acne vulgaris und Seborrhoe, Rosacea, Psoriasis vulgaris, Parapsoriasis, Lupus erythematodes

Dermatology — Wed, 28 Oct 2009 23:00:00 +0100

Dermatologica 1948;95:91-101 (DOI:10.1159/000255936) (Source: Dermatology)

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Uncommon etiology of an anterior chest wall mass.

The Annals of Thoracic Surgery — Tue, 27 Oct 2009 12:29:52 +0100

Authors: Schwartz GS, Rios L, Zivin-Tutela T, Bhora FY, Connery CP A rare but important constellation of musculoskeletal and cutaneous symptoms, including synovitis, acne, pustulosis, hyperostosis, and osteitis, has recently been designated the SAPHO syndrome. The exact etiology is unknown, although various infectious agents have been proposed. The most common site of osteoarticular involvement is the sternoclavicular joint, and therefore, recognition of this syndrome and appropriate workup and management is crucial in the differential diagnosis of an anterior chest wall mass. PMID: 19853079 [PubMed - in process] (Source: The Annals of Thoracic Surgery)

The individual health burden of acne: Appearance-related distress in male and female adolescents and adults with back, chest and facial acne

Journal of Health Psychology — Mon, 26 Oct 2009 16:37:51 +0100

This study examined appearance-related distress in patients with acne. One hundred and thirty-two people attending a specialist acne clinic completed questionnaires including the Derriford Appearance Scale and three self-rated acne scales covering more (facial) and less visible (chest, back) acne sites. Women with acne demonstrated greater self-consciousness of appearance and negative self-concept than men. Subjective rating of severity of facial acne was significantly associated with increased social self-consciousness in women, but not in men. Back acne was significantly associated with sexual and bodily self-consciousness of appearance in both men and women. Patients 20 years and above were significantly more likely to suffer appearance-related distress than 16—19-year-olds. Altho...

Acne in women: clinical patterns in different age-groups

Anais Brasileiros de Dermatologia — Fri, 23 Oct 2009 12:59:34 +0100

CONCLUSION: Chronologic and topographic patterns of female acne in different age-groups were defined, reinforcing the importance of an individualized diagnostic and therapeutic approach. (Source: Anais Brasileiros de Dermatologia)

Management of acne vulgaris: an evidence-based update

Clinical And Experimental Dermatology — Thu, 22 Oct 2009 23:00:00 +0100

This review summarizes clinically important findings from 3 systematic reviews, 1 updated guideline and a selection from the 62 randomized controlled trials (RCTs) published between February 2007 and January 2009 on the topic of acne vulgaris. Low glycaemic-load diets might reduce acne severity but this remains unproven. Written patient information leaflets have not been surpassed by other communication methods. New combination topical treatments have not shown convincing advantages over current combination products such as clindamycin/benzoyl peroxide. Topical dapsone is superior to placebo but has yet to be compared with standard topical treatments. Long-term topical tretinoin to prevent nonmelanoma skin cancer in elderly men was associated with higher all-cause mortality, but there is c...

Immune reconstitution inflammatory syndrome involving the skin

Clinical And Experimental Dermatology — Thu, 22 Oct 2009 23:00:00 +0100

Conclusions. New skin lesions were very common in this cohort, with the majority being women and patients with very low baseline CD4 counts. (Source: Clinical And Experimental Dermatology)

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Uncommon Etiology of an Anterior Chest Wall Mass [CASE REPORTS]

The Annals of Thoracic Surgery — Thu, 22 Oct 2009 18:54:54 +0100

A rare but important constellation of musculoskeletal and cutaneous symptoms, including synovitis, acne, pustulosis, hyperostosis, and osteitis, has recently been designated the SAPHO syndrome. The exact etiology is unknown, although various infectious agents have been proposed. The most common site of osteoarticular involvement is the sternoclavicular joint, and therefore, recognition of this syndrome and appropriate workup and management is crucial in the differential diagnosis of an anterior chest wall mass. (Source: The Annals of Thoracic Surgery)

With Microdermabrasion, Rough Seems to Work Better

MedlinePlus Health News — Wed, 21 Oct 2009 13:00:00 +0100

Acne scars and wrinkles benefit from more aggressive treatment, study finds Source: HealthDay Related MedlinePlus Topic: Plastic and Cosmetic Surgery (Source: MedlinePlus Health News)

RESEARCH LETTERS: Physician Workforce for Acne Care in the United States, 2003 Through 2005

Archives of Dermatology — Mon, 19 Oct 2009 19:52:13 +0100

(Source: Archives of Dermatology)

Physician Workforce for Acne Care in the United States, 2003 Through 2005 [Research Letters]

Archives of Dermatology — Mon, 19 Oct 2009 19:52:13 +0100

(Source: Archives of Dermatology)

Dusa targets skin cancer to blunt downturn’s effects

bizjournals.com Health Care:Health Insurance headlines — Mon, 19 Oct 2009 04:00:00 +0100

The downturn has been particularly cruel to laser dermatology companies, which often rely on nonessential treatments that patients must pay for out of pocket. Companies with laser treatments for acne, hair removal and the like have faced the double whammy of patients tightening purse strings and doctors who are hamstrung by the credit crunch and can’t purchase the latest equipment. (Source: bizjournals.com Health Care:Health Insurance headlines)

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Dusa targets skin cancer to blunt downturn’s effects

bizjournals.com Health Care:Biotechnology headlines — Mon, 19 Oct 2009 04:00:00 +0100

A case of SAPHO syndrome with destructive spondylodiscitis suspicious of tuberculous spondylitis

Modern Rheumatology — Thu, 15 Oct 2009 06:00:15 +0100

We report a rare case of synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome in which the differential diagnosis included tuberculous spondylitis and the patient ultimately required reconstructive spinal surgery. The patient was a 60-year-old woman who presented with severe low-back and leg pain after treatment for tuberculosis. Roentgenography and magnetic resonance imaging of the lumbar spine revealed destructive changes suggestive of tuberculous spondylitis. [18F]-fluoro-2-deoxyglucose positron emission tomography/computed tomography showed uptake in the cervical spines, lumbar spines, and sacroiliac joints from which she was suspected of having SAPHO syndrome without skin manifestations. However, as her symptoms did not respond to conservative treatment, we perfor...

II. Zur Kenntnis der Pathogenese der Perifolliculitis capitis abscedens et suffodiens (E. Hoffmann) und ihrer Beziehungen zur Acne conglobata

Dermatology — Wed, 14 Oct 2009 23:00:00 +0100

Dermatologische Zeitschrift 1928;51:94-107 (DOI:10.1159/000251817) (Source: Dermatology)

Natural remedies for acne

NaturalNews.com — Wed, 14 Oct 2009 07:00:00 +0100

(NaturalNews) Acne sucks. But you don't need antibiotics or harsh chemicals to treat it. In addition to altering your diet so that you consume fewer acne-producing foods (dairy products and fried foods, mostly), there are some effective natural remedies that are also useful for clearing up your skin.Below, we've compiled a few of these recommendations from some of the top authors in natural health. Enjoy this short collection, and feel free to share it with others (please give appropriate credit to the original author as well as this NaturalNews page, thank you).Natural remedies for acneBrazilian school kids have acne. There's far less acne in Kenya, Zambia, Malaysia, and rural Japan than is common in Western societies. But if there was any doubt left about the diet-acne connection it shou...

Quality of Sexual Life in Hyperandrogenic Women Treated with an Oral Contraceptive Containing Chlormadinone Acetate

The Journal of Sexual Medicine — Tue, 13 Oct 2009 23:00:00 +0100

Conclusion(s). The EE/CMA pill has anti-androgenic properties reducing the anti-aesthetic effect of hyperandrogenism and improving female sexual and social self-esteem. Caruso S, Rugolo S, Agnello C, Romano M, and Cianci A. Quality of sexual life in hyperandrogenic women treated with an oral contraceptive containing chlormadinone acetate. J Sex Med **;**:**[ndash]**. (Source: The Journal of Sexual Medicine)

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New Study Assesses Skin Hydration And Epidermal Function Of 2.5% And 5% Benzoyl Peroxide-Clindamycin Combinations

Drugs.com - Clinical Trials — Tue, 13 Oct 2009 13:01:27 +0100

Las Vegas, NV – October 15, 2009 – Dermatologists agree that topical fixed-combination products containing clindamycin (clin) and benzoyl peroxide (BPO) are effective in the treatment of acne. However, products containing BPO... (Source: Drugs.com - Clinical Trials)

Effect of konjac glucomannan hydrolysates and probiotics on the growth of the skin bacterium Propionibacterium acnes in vitro

International Journal of Cosmetic Science — Sat, 10 Oct 2009 23:00:00 +0100

The synbiotic ability of probiotic bacteria and konjac glucomannan hydrolysates (GMH) to inhibit acne-inducing bacterium, Propionibacterium acnes growth was studied in vitro. All probiotic bacteria strains tested were able to inhibit the growth of this species of skin bacterium where the inhibition was significantly (P < 0.01) enhanced by the presence of the GMH prebiotic. As the current treatment of acne is based on topical or systemic drugs, it is worth examining further the biotherapeutic activities of the GMH and selected probiotics with a view to future use as prophylactic or therapeutic synbiotics for treating acne infections. La capacité synbiotic des bactéries probiotic et des hydrolysats glucomannan konjac (GMH) d'empêcher l'acné - induisant des bactérie, la croissance d'acn�...

Antibiotics Control SAPHO Syndrome, but Symptoms Recur When Therapy Stops

Medscape Rheumatology Headlines — Thu, 08 Oct 2009 17:32:02 +0100

Although SAPHO syndrome - which stands for synovitis, acne, pustulosis, hyperostosis, and osteomyelitis - responds to antibiotics, discontinuing the medication leads to relapse, German researchers report in the September 21st online issue of Arthritis Research and Therapy. Reuters Health Information (Source: Medscape Rheumatology Headlines)

New insights into synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome

Current Rheumatology Reports — Tue, 06 Oct 2009 12:59:21 +0100

Abstract In 1987, synovitis, acne, pustulosis, hyperostosis and osteitis (SAPHO) syndrome was proposed as an umbrella term for a group of diseases with similar musculoskeletal manifestations, in particular hyperostosis of anterior chest wall, synovitis, and multifocal aseptic osteomyelitis, observed in association with dermatologic conditions such as palmoplantar pustulosis, severe acne, and hidradenitis suppurativa. Despite recent advances in our understanding of the epidemiologic, pathophysiologic, and immunogenetic mechanisms involved in SAPHO syndrome, etiopathogenesis remains poorly understood. Propionibacterium acnes, the microorganism associated with acne, has been recovered on bone biopsy in some patients, but the possible pathogenetic role of an infectious agent in...

Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-κB and MAPK pathways

Journal of Dermatological Science — Mon, 05 Oct 2009 16:28:46 +0100

Conclusion: Our results indicate that nicotinamide inhibits IL-8 production through the NF-κB and MAPK pathways in an in vitro keratinocytes/P. acnes model of inflammation. Keratinocytes involved in the innate immune response may be a suitable target for treatment during the early phase of inflammation. (Source: Journal of Dermatological Science)

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Nonbacterial osteitis: a clinical, histopathological, and imaging study with a proposal for protocol-based management of patients with this diagnosis

Journal of Orthopaedic Science — Sat, 03 Oct 2009 06:33:48 +0100

Conclusions On the basis of our findings, we propose using a patient questionnaire and protocol for investigating and managing patients who present with NBO to orthopedic surgeons. We predict that this will benefit patients with this disorder by improving our knowledge of the presenting signs and symptoms and related disorders, rationalizing the therapeutic approach, and allowing us to learn about the natural history of the disease. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00776-009-1381-4Authors Panagiotis D. Gikas, Bone Tumour Unit, Royal National Orthopaedic Hospital Stanmore, Middlesex UKLily Islam, Royal National Orthopaedic Hospital Department of Histopathology Stanmore, Middlesex UKWilliam Aston, Bone Tumour Unit, Royal National Orthop...

11. Acne, Psoriasis, and Disorders of Keratinization

Medical and Surgical Dermatology — Sat, 03 Oct 2009 06:33:24 +0100

Content Type Journal ArticleDOI 10.1007/s00533-009-0166-2 Journal Medical and Surgical DermatologyOnline ISSN 1934-2853Print ISSN 0944-5196 (Source: Medical and Surgical Dermatology)

50 years ago from the Connecticut State Medical Journal. October 1959. Radiation therapy of acne.

Connecticut Medicine — Thu, 01 Oct 2009 00:00:00 +0100

Authors: Strauss JS PMID: 19860280 [PubMed - in process] (Source: Connecticut Medicine)

Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid 0.5% liposomal spray and intense pulsed light in combination with topical keratolytic agents

Journal of the European Academy of Dermatology and Venereology — Wed, 30 Sep 2009 23:00:00 +0100

Conclusion Photodynamic therapy of acne vulgaris using 5-ALA 0.5% liposomal spray and IPL in combination with topical peeling agents is safe and efficacious, even in patients with acne recalcitrant to standard therapy. (Source: Journal of the European Academy of Dermatology and Venereology)

[Pandalao and skin whitening in Mayotte.]

Annales de Dermatologie et de Cenereologie — Wed, 30 Sep 2009 23:00:00 +0100

DISCUSSION: Although illegal, the trade in skin whitening products continues to grow because it is profitable and takes full advantage of the success of ethnic cosmetics. In Mayotte, as in metropolitan France and Africa, the existence of SW is acknowledged but is still taboo. However, a number of specific characteristics are seen in Mayotte: SW is rarely performed on the whole body, salicylic acid is added to a topical corticosteroid, and the traditional Mahoran mask, the "mzindzano", is still worn for photoprotection. PMID: 19801250 [PubMed - in process] (Source: Annales de Dermatologie et de Cenereologie)

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Multimodal Treatment of Acne, Acne Scars and Pigmentation

Dermatologic Clinics — Wed, 30 Sep 2009 23:00:00 +0100

This article reviews the causes of acne, the treatment options, and grading scales. (Source: Dermatologic Clinics)

Nonablative Fractional Laser Resurfacing

Dermatologic Clinics — Wed, 30 Sep 2009 23:00:00 +0100

This article discussed the science, clinical indications, patient selection and preparation, posttreatment care, and complications of NFR. It concludes that the most impressive clinical results are seen with acne scars, surgical and traumatic scars, and mild to moderate facial and nonfacial dyschromia or photoaging. Modest results can be seen with therapy-resistant melasma and certain types of rhytides. Future approaches include synergistic treatments with radiofrequency devices and the development of novel wavelengths to enhance the efficacy of NFR while preserving safety. (Source: Dermatologic Clinics)

Emerging Technologies in Aesthetic Medicine

Dermatologic Clinics — Wed, 30 Sep 2009 23:00:00 +0100

Recent advances in technology have drastically improved aesthetic treatment for skin. Of particular interest is the emergence of laser- and lightbased technologies, which have offered great promise among skin-rejuvenation therapies. New laser resurfacing techniques for skin rejuvenation offer significant advantages over conventional ablative lasers, such as the CO2 and erbiumYAG laser systems. Nonablative and fractional lasers, although not as efficacious as ablative therapies, are associated with significantly diminished complication rates and shortened recovery times. Novel devices combining ablative and fractional technologies have also surfaced, demonstrating noteworthy results. In this review, the authors will discuss the implications of current developments in research and technology...

Health advice: 'Is there a cure for a son who's uncommunicative and sullen?'

The Telegraph : Health Advice — Wed, 30 Sep 2009 16:05:12 +0100

Britain's leading health and wellbeing specialists answer your questions: This week: an uncommunicative son. (Source: The Telegraph : Health Advice)

Fact Checking Anecdotes: Obama Wrong On Particulars In Cancer And Acne Insurance Denial Case

Health News from Medical News Today — Wed, 30 Sep 2009 12:00:00 +0100

When President Obama recently recounted the story of a woman he said was denied coverage for failure to own up to a skin condition when she enrolled in a plan, he was incorrect, The Associated Press reports. "Robin Lynn Beaton, 59, of Waxahachie, Texas, indeed had her insurance suspended and then terminated when she needed it the most. (Source: Health News from Medical News Today)

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Cervical and Vulvar Intraepithelial Neoplasia after Treatment with Oral Isotretinoin for Severe Acne Vulgaris

Karger Publishers — Tue, 29 Sep 2009 23:00:00 +0100

Case Rep Dermatol 2009;1:49-51 (DOI:10.1159/000236034) (Source: Karger Publishers)

Fractional photothermolysis—an update

Lasers in Medical Science — Tue, 29 Sep 2009 07:33:03 +0100

Abstract The novel concept of non-ablative fractional photothermolysis was introduced to the market in 2003 as an answer to the need for effective, yet low risk, resurfacing techniques. Unlike conventional ablative and non-ablative lasers, fractional ablative and non-ablative photothermolysis treats only a fraction of the skin, leaving up to a maximum of 95% of the skin uninvolved. The undamaged surrounding tissue allows for a reservoir of viable tissue, permitting rapid epidermal repair. Non-ablative fractional photothermolysis is currently approved by the US Food and Drug Administration (FDA) for the treatment of pigmented lesions, periorbital rhytides, skin resurfacing, melasma and soft tissue coagulation, acne and surgical scars, and actinic keratoses. However, its off...

FACT CHECK: In health debate, Obama's stories of hardship don't always hold up to scrutiny

OrlandoSentinel: Medical Research — Mon, 28 Sep 2009 23:09:00 +0100

WASHINGTON (AP) — One of President Barack Obama's health care "horror stories" is about a woman who, he says, lost her health insurance on the verge of breast cancer surgery because she didn't disclose a case of acne to the insurer. That's not... (Source: OrlandoSentinel: Medical Research)

Management of cutaneous side-effects of cetuximab therapy in patients with metastatic colorectal cancer

Journal of the European Academy of Dermatology and Venereology — Sat, 26 Sep 2009 23:00:00 +0100

Conclusion During the treatment with EGFRI, it is necessary to recognize and manage adverse reactions promptly to assure better patient quality of life and allowing continuation of therapy without dose reduction or drug discontinuation. (Source: Journal of the European Academy of Dermatology and Venereology)

Birth control pills for acne?

MayoClinic.com Full Feed — Wed, 23 Sep 2009 01:45:02 +0100

Birth controls pills for acne may be helpful in some women. Learn more. Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)

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Birth control pills for acne?

MayoClinic.com - Ask a Specialist — Tue, 22 Sep 2009 05:00:00 +0100

Birth controls pills for acne may be helpful in some women. Learn more. Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com - Ask a Specialist)

Efficacy of antibiotic therapy for SAPHO syndrome is lost after its discontinuation: interventional study

Arthritis Research and Therapy — Sun, 20 Sep 2009 23:00:00 +0100

Conclusions: For the period of application, the antibiotic therapy seems to have controlled the disease. After antibiotics discontinuation however, disease relapse was observed. SAPHO syndrome thus groups with other chronic inflammatory arthropathies with a need of permanent therapy. (Source: Arthritis Research and Therapy)

OBSERVATION: Interaction of Topical Sulfacetamide and Topical Dapsone With Benzoyl Peroxide

Archives of Dermatology — Sun, 20 Sep 2009 23:00:00 +0100

Conclusions Knowledge of the chemical reaction between benzoyl peroxide and sulfacetamide and dapsone will help minimize the occurrence of this interaction on our patients' skin. (Source: Archives of Dermatology)

Poor diet may increase risk for acne in adolescent girls

MedWire News - Pediatrics — Sat, 19 Sep 2009 17:00:47 +0100

Results from a Norwegian study indicate that adolescent girls who rarely eat raw, fresh vegetables may be at increased risk for acne. (Source: MedWire News - Pediatrics)

Teen Acne and Depression: Can Mood Worsen Skin?

TIME.com: Top Science and Health Stories — Fri, 18 Sep 2009 16:15:00 +0100

A survey of Norwegian teenagers finds that depression and acne often appear together. Could kids' mood be affecting the blemishes on their skin? (Source: TIME.com: Top Science and Health Stories)

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Poor diet may increase risk for acne in adolescent girls

MedWire News - Dermatology — Fri, 18 Sep 2009 00:00:00 +0100

Results from a Norwegian study indicate that adolescent girls who rarely eat raw, fresh vegetables may be at increased risk for acne. (Source: MedWire News - Dermatology)

Efficacy and safety profiles of cetuximab in Chinese patients with colorectal cancer

The Chinese-German Journal of Clinical Oncology — Thu, 17 Sep 2009 12:25:10 +0100

Conclusion This study is the first study to summarize the data of Chinese patients with colorectal cancer treated by cetuximab-contained regimen, it showed that the monoclonal antibody was effective and safe for Chinese patients as the West patients with colorectal cancer. Content Type Journal ArticleDOI 10.1007/s10330-009-0062-2Authors Liangping Xia, Sun Yat-sen University, National Laboratory of Oncology in South China VIP Region, Cancer Center Guangzhou 510060 ChinaGuifang Guo, Sun Yat-sen University, National Laboratory of Oncology in South China VIP Region, Cancer Center Guangzhou 510060 ChinaHuijuan Qiu, Sun Yat-sen University, National Laboratory of Oncology in South China VIP Region, Cancer Center Guangzhou 510060 ChinaBei Zhang, Sun Yat-sen University, Nation...

Acne Really Is A Nightmare For Some Teens

Health News from Medical News Today — Thu, 17 Sep 2009 10:00:00 +0100

Zits, pimples, bumps and blemishes are a young person's worst nightmare. Collectively they are known as acne, a very common skin condition that affects millions of adolescents. Now a Norwegian study published in the open access journal BMC Public Health has investigated the links between acne, diet and mental health issues in both males and females. (Source: Health News from Medical News Today)

Less chocolate, more veggies may help acne

Health News - UPI.com — Wed, 16 Sep 2009 18:24:48 +0100

OSLO, Norway, Sept. 16 (UPI) -- Researchers in Norway have made associations between acne, high intake of chocolate and chips and low intake of vegetables. (Source: Health News - UPI.com)

Is the association between acne and mental distress influenced by diet? Results from a cross-sectional population study among 3775 late adolescents in Oslo, Norway.

BMC Public Health - Latest articles — Tue, 15 Sep 2009 23:00:00 +0100

Conclusions: Among late adolescents in Oslo, self-reported acne is significantly associated with mental distress and, among girls, with infrequent consumption of raw vegetables. Our finding does not support the hypothesis that dietary factors alter the relationship between acne and mental distress. (Source: BMC Public Health - Latest articles)

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Acne really is a nightmare for some teens

EurekAlert! - Social and Behavioral Science — Tue, 15 Sep 2009 04:00:00 +0100

(BioMed Central) Zits, pimples, bumps and blemishes are a young person's worst nightmare. Collectively they are known as acne, a very common skin condition that affects millions of adolescents. Now a Norwegian study published in the open access journal BMC Public Health has investigated the links between acne, diet and mental health issues in both males and females. (Source: EurekAlert! - Social and Behavioral Science)

Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report

Journal of Medical Case Reports — Mon, 14 Sep 2009 23:00:00 +0100

Conclusion: We demonstrate the expression of TNF-alpha converting enzyme, TNF-alpha and matrix metalloproteinase-3 in SAPHO syndrome synovitis for the first time and also show, both macro- and microscopically, the similarity between SAPHO syndrome and rheumatoid arthritis synovitis. These new findings support the recently reported successful treatment of SAPHO syndrome with antirheumatic drugs, especially with anti-TNF-alpha agents. (Source: Journal of Medical Case Reports)

Acne: guide to features and recommended management

Prescriber — Mon, 14 Sep 2009 23:00:00 +0100

Acne typically presents during puberty and can cause significant psychological morbidity and facial scaring. Our Drug review describes the underlying aetiology of acne development and the available treatments, followed by a review of the prescription data and sources of further information. Copyright © 2009 Wiley Interface Ltd (Source: Prescriber)

Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report

Journal of Medical Case Reports — Mon, 14 Sep 2009 23:00:00 +0100

Depressive symptoms and suicidal ideation during isotretinoin treatment: a 12-week follow-up study of male Finnish military conscripts. - Rehn L, Meririnne E, Höök-Nikanne J, Isometsä E, Henriksson M.

SafetyLit: All (Unduplicated) — Sun, 13 Sep 2009 17:20:01 +0100

Objective: To investigate the putative association between isotretinoin treatment and depressive symptoms or suicidal ideation among Finnish male military conscripts. Methods Consecutive acne patients were enrolled into an uncontrolled, prospective 12-week... (Source: SafetyLit: All (Unduplicated))

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Treatment of Acne Rosacea Reviewed

Medscape Nurses Headlines — Fri, 11 Sep 2009 16:08:28 +0100

Topical metronidazole, sulfacetamide/sulfur, and azelaic acid are generally effective for mild rosacea; combination therapy is the first-line choice for moderate papulopustular rosacea. Medscape Medical News (Source: Medscape Nurses Headlines)

XXIV.Ueber den Primäraffect der Acne, des Gesichtslupus, des Lepra und anderer Krankheiten der Lymphcapillaren

Dermatology — Thu, 10 Sep 2009 23:00:00 +0100

Dermatologische Zeitschrift 1898;5:758-767 (DOI:10.1159/000239737) (Source: Dermatology)

Weight-based dosing: Extended-release minocycline efficient, predictable

Modern Medicine — Thu, 10 Sep 2009 23:00:00 +0100

Las Vegas — Weight-based dosing with extended-release (ER) minocycline tablets allows patients with acne to achieve efficacy equivalent to that of 2 mg/kg or 3 mg/kg of body weight daily with just 1 mg/kg daily, says James Q. Del Rosso, D.O., dermatology residency director, Valley Hospital Medical Center, Las Vegas. (Source: Modern Medicine)

Cutaneous remodeling and photorejuvenation using radiofrequency devices

Indian Journal of Dermatology — Thu, 10 Sep 2009 16:21:51 +0100

Elsaie Mohamed LotfyIndian Journal of Dermatology 2009 54(3):201-205Radio frequency (RF) is electromagnetic radiation in the frequency range of 3-300GHz. The primary effects of RF energy on living tissue are considered to be thermal. The goal of the new devices based on these frequency ranges is to heat specific layers of the skin. The directed use of RF can induce dermal heating and cause collagen degeneration. Wound healing mechanisms promote the remodeling of collagen and wound contraction, which ultimately clinically enhances the appearance of mild to moderate skin laxity. Preliminary studies have reported efficacy in the treatment of laxity that involves the periorbital area and jowls. Because RF energy is not dependent on specific chromophore interaction, epidermal melanin is not at ...

The 'Holi' dermatoses : Annual spate of skin diseases following the spring festival in India

Indian Journal of Dermatology — Thu, 10 Sep 2009 16:21:51 +0100

Conclusion : Various forms of cutaneous manifestations, often associated with ocular complaints, occur commonly due to Holi colors. Public awareness and regulatory actions are needed to avoid these preventable conditions. (Source: Indian Journal of Dermatology)

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Prevalence of depression, its correlates among students, and its effect on health-related quality of life in a Turkish university.

Upsala Journal of Medical Sciences — Wed, 09 Sep 2009 23:48:03 +0100

Conclusions.The prevalence of depression among the university students in this region of Turkey was wide-spread, affecting negatively the HRQoL of the students. For prevention and control of depression, depression information and knowledge need to be addressed by health education programs. PMID: 19736608 [PubMed - in process] (Source: Upsala Journal of Medical Sciences)

Fractional 1320 nm Nd : YAG laser in the treatment of acne vulgaris: a pilot study

Photodermatology, Photoimmunology and Photomedicine — Sun, 06 Sep 2009 23:00:00 +0100

Thirty-five patients with moderate to severe acne were treated with a fractional 1320 nm neodymium : yttrium aluminum garnet (Nd : YAG) laser. These patients received six treatment sessions at a 2-week interval. Inflammatory and non-inflammatory lesions were counted before and after treatment. Fractional 1320 nm Nd : YAG laser therapy was well tolerated, resulting in the reduction of inflammatory lesions by 57% (P (Source: Photodermatology, Photoimmunology and Photomedicine)

Elevated Testosterone and Hypergonadotropism in Active Adolescents of Normal Weight with Oligomenorrhea

Journal of Pediatric and Adolescent Gynecology — Fri, 04 Sep 2009 17:02:13 +0100

Abstract: Study Objective: Oligomenorrhea in active adolescent females of normal weight is presumed to be related to hypoestrogenism secondary to physical activity and decreased fat mass. We hypothesized that active adolescents with oligomenorrhea would have lower estrogen levels than normal controls with similar levels of cardiovascular fitness.Design/Participants: Twenty healthy participants between the ages of 16 and 20 years were recruited at least 2 years postmenarche. Adolescents reporting fewer than 9 cycles a year (n = 6) were compared to 14 controls with monthly menstrual cycles. Histories of eating disorder, hirsutism, severe acne, depression, or amenorrhea were cause for exclusion.Main Outcome Measures: Body composition and bone density were measured by total body dual x-ray abs...

[Skin manifestations, treatment and rehabilitation in overweight and obesity.]

Orvosi Hetilap — Fri, 04 Sep 2009 11:26:19 +0100

Authors: Wenczl E Overweight and obesity is a public health problem in Hungary and in the Western world. It is important to underline that obesity is an illness and an important risk factor for several skin and other diseases. An overview of skin diseases caused or aggravated by obesity (acanthosis nigricans, acrochordons, keratosis pilaris, hyperandrogenism, stria, adiposis dolorosa, lymphoedema, chronic venous insufficiency, plantar hyperkeratosis, lipoedema, skin infections, acne inversa, psoriasis, tophi) helps us to look and see as well. Look for the possibility of skin infections as it helps the early diagnosis and to avoid complications. Draw patients' attention to the preventive importance of skin care. In case of an obese patient the usual dosage of most local and systemic dru...

Family history linked to acne in teens

Reuters: Health — Thu, 03 Sep 2009 16:25:11 +0100

NEW YORK (Reuters Health) - Teenagers' odds of developing moderate to severe acne may depend largely on whether their parents had the problem, a new study suggests. (Source: Reuters: Health)

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Teens Fight Acne Before School Starts

WDSU.com - Health — Thu, 03 Sep 2009 12:12:38 +0100

Dealing with acne can be difficult and embarrassing for teens. Try these tips to help your teen cope. (Source: WDSU.com - Health)

Specific gel-cream as adjuvant to oral isotretinoin improved hydration and prevented TEWL increase – a double-blind, randomized, placebo-controlled study

Journal of Cosmetic Dermatology — Mon, 31 Aug 2009 23:00:00 +0100

Conclusions Compared with placebo, the specific gel-cream with active products as an adjuvant to oral isotretinoin improved hydration, prevented TEWL increase, and reduced inflammatory acne lesions after 30 days. (Source: Journal of Cosmetic Dermatology)

Treating PIH: Combination therapies appropriate for troublesome condition

Modern Medicine — Mon, 31 Aug 2009 23:00:00 +0100

Therapies that combine hydroquinone and other compounds can be prescribed to treat PIH, which can appear secondary to eczema, acne. (Source: Modern Medicine)

[Facial dystrophic calcinosis cutis secondary to acne.]

Actas Dermo-Sifiliograficas — Mon, 31 Aug 2009 23:00:00 +0100

Authors: Saavedra T, Mardones F, Sazunic I, Wortsman X PMID: 19715653 [PubMed - in process] (Source: Actas Dermo-Sifiliograficas)

Should dermatologists prescribe hormonal contraceptives for acne?

Dermatologic Therapy — Mon, 31 Aug 2009 23:00:00 +0100

One of the primary factors contributing to the development of acne vulgaris is excess sebum. Sebaceous glands and sebum excretion are regulated, at least in part, by androgen hormones. Acne treatments that block this androgen effect include spironolactone and combination oral contraceptives (COC). Three COC are now FDA approved to treat moderate acne. Dermatologists must become experts at prescribing these hormonal contraceptives. Likewise, it is vital to be aware of contraindications to hormonal contraceptive therapy. Proper patient selection relies on an appropriate medical history and an assessment of blood pressure. A pelvic exam and/or Papanicolaou smear are not required prior to initiating therapy with a COC. It is important to counsel patients about potential adverse effects of COC ...

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FDA warns Allergan on Aczone promotion

Modern Medicine — Mon, 31 Aug 2009 23:00:00 +0100

Washington ?An advertisement for Aczone (Allergan), a gel used to treat mild-to-moderate acne, "grossly overstates" the drug?s effectiveness, the Food and Drug Administration (FDA) stated in a letter released Aug. 21. (Source: Modern Medicine)

Treatment options for acne rosacea.

American Family Physician — Mon, 31 Aug 2009 23:00:00 +0100

Authors: Goldgar C, Keahey DJ, Houchins J Rosacea is a common chronic, and sometimes progressive, dermatosis. It is characterized, alone or in combination, by central facial erythema,symmetric flushing, stinging sensation, inflammatory lesions (papules and pustules), telangiectasias, and phymatous changes (tissue hyperplasia and nodules). Rosacea can occur in adults of any ethnicity,and adversely affects patients' quality of life. The condition can be effectively controlled with therapy tailored to the specific subtype of rosacea that is affecting the patient. Topical metronidazole, sulfacetamide/sulfur, and azelaic acid are generally effective for patients with mild rosacea. For moderate papulopustular rosacea, combination therapy with oral tetracyclines and topical agents is the firs...

[Short-term efficacy of cetuximab combined with radiotherapy or chemotherapy on head and neck cancer: a report of 11 cases.]

Ai Zheng — Mon, 31 Aug 2009 23:00:00 +0100

Conclusion: Cetuximab combined wthe either radiotherapy or chemotherapy are good options for suitable patients with head and neck cancer. PMID: 19728918 [PubMed - in process] (Source: Ai Zheng)

Patient Age, Severity Should Guide Acne Tx

Skin and Allergy News — Mon, 31 Aug 2009 23:00:00 +0100

SEATTLE — The treatment of acne in adolescents should be tailored to the type and severity of lesions and the adolescent's age, according to Dr. Annette Wagner. Fully 80% of teenagers develop acne, noted Dr. Wagner, a pediatric dermatologist at Northwestern University in Chicago. “But the age of onset is really young now that puberty is starting earlier,” she commented. “I see comedones on many 8-year-olds in my clinic.” (Source: Skin and Allergy News)

Ciclosporin: Nodulocystic acne in an infant: case report

Reactions — Mon, 31 Aug 2009 12:03:34 +0100

(Source: Reactions)

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Case report Conglobate acne in a pregnant woman – an important therapeutic problem. A case report

Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house — Sun, 30 Aug 2009 09:12:17 +0100

A case of a 29-year-old pregnant woman suffering from conglobate acne that appeared in the 1st trimester is presented. The influence of pregnancy on the course of acne as well as limitation of anti-acne treatment is discussed. The severe course of acne in this patient required systemic antibiotic treatment followed by laser therapy to correct post-inflammatory lesions. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)

Acne Vulgaris: Review and Guidelines

Medscape Dermatology Headlines — Fri, 28 Aug 2009 20:33:33 +0100

Learn more about acne’s pathophysiology, topical treatments, oral medications, and follow-up strategies. Dermatology Nursing (Source: Medscape Dermatology Headlines)

Prescription "Sharing" Among Teens Widespread, Dangerous

Health Behavior News Service — Fri, 28 Aug 2009 12:24:15 +0100

08/10/2009, Journal of Adolescent Health, What if a teenager with acne who is taking Accutane - a drug linked to birth defects - gives some to her friend, who is pregnant but does not yet realize it? Unfortunately, this is a realistic scenario. (Source: Health Behavior News Service)

Mylan Begins Marketing First Generic Version of BenzaClin(R) Acne Treatment

HSMN NewsFeed — Thu, 27 Aug 2009 14:56:34 +0100

PITTSBURGH, Aug. 27 (HSMN NewsFeed) -- Mylan Inc. (Nasdaq: MYL ) today announced that its subsidiary Mylan Pharmaceuticals Inc. has begun to market 1% Clindamycin and 5% Benzoyl Peroxide Gel based on an agreement with licensing partner Dow Pharmaceutical... Biopharmaceuticals, Generics, DermatologyMylan, Clindamycin, Benzoyl Peroxide, BenzaClin, sanofi-aventis, acne (Source: HSMN NewsFeed)

Mylan Begins Marketing First Generic Version Of BenzaClin(R) Acne Treatment

Pharmaceutical Online News — Thu, 27 Aug 2009 12:40:00 +0100

Mylan Begins Marketing First Generic Version of BenzaClin(R) Acne Treatment (Source: Pharmaceutical Online News)

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Pyogenic arthritis, pyoderma gangrenosum, and acne syndrome (PAPA syndrome): Report of a sporadic case without an identifiable mutation in the CD2BP1 gene

Journal of the American Academy of Dermatology — Wed, 26 Aug 2009 11:59:01 +0100

To the Editor: Autosomal dominant PAPA syndrome (pyogenic arthritis, pyoderma gangrenosum [PG], and acne) was first described in 1997 as an unusual triad of pyogenic sterile arthritis, PG, and acne conglobata. The linkage of CD2-binding protein 1 (CD2BP1) gene mutation in patients with PAPA syndrome has been confirmed. Herein, we describe a sporadic case of PAPA syndrome without an identifiable mutation in the CD2BP1 gene. (Source: Journal of the American Academy of Dermatology)

Adapalene-benzoyl peroxide (epiduo) for acne.

Obstetrics and Gynecology — Wed, 26 Aug 2009 10:14:29 +0100

Authors: PMID: 19701055 [PubMed - in process] (Source: Obstetrics and Gynecology)

Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris

Experimental Dermatology — Tue, 25 Aug 2009 23:00:00 +0100

Please cite this paper as: Role of insulin, insulin-like growth factor-1, hyperglycaemic food and milk consumption in the pathogenesis of acne vulgaris. Experimental Dermatology 2009.Abstract: It is the purpose of this viewpoint article to delineate the regulatory network of growth hormone (GH), insulin, and insulin-like growth factor-1 (IGF-1) signalling during puberty, associated hormonal changes in adrenal and gonadal androgen metabolism, and the impact of dietary factors and smoking involved in the pathogenesis of acne. The key regulator IGF-1 rises during puberty by the action of increased GH secretion and correlates well with the clinical course of acne. In acne patients, associations between serum levels of IGF-1, dehydroepiandrosterone sulphate, dihydrotestosterone, acne lesion cou...

The Efficacy and Safety of 10,600-nm Carbon Dioxide Fractional Laser for Acne Scars in Asian Patients

Dermatologic Surgery — Tue, 25 Aug 2009 23:00:00 +0100

The nonablative 1,550-nm erbium-doped fractional photothermolysis system (FPS) has been effectively used for scar treatments, but it seems that several sessions of treatment must be delivered to achieve satisfactory improvement. To evaluate the efficacy and safety of the combined use of two treatment modes of an ablative 10,600-nm carbon dioxide fractional laser system (CO2 FS) on acne scars. Twenty Korean patients with atrophic acne scars treated with a single session of Ultrapulse Encore laser (Lumenis Inc., Santa Clara, CA) were enrolled. The laser fluences were delivered to the scars using the Deep FX mode. Additional treatment using the Active FX mode was performed throughout the entire face. Follow-up results revealed that one patient had clinical improvement of 76% to 100%, nine had...

Panniculitis: clinical overlap and the significance of biopsy findings

Journal of Cutaneous Pathology — Tue, 25 Aug 2009 23:00:00 +0100

Conclusions: Biopsy evaluation of a panniculitis lesion is usually significant, and the application of a combination of histologic features rather than of a single biopsy finding or an inflammatory pattern is helpful in the diagnosis of panniculitis. Rajan C, Seema C, Gurvinder Pal T, Raj Pal Singh P. Panniculitis: the clinical overlap and the significance of biopsy findings. (Source: Journal of Cutaneous Pathology)

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A Comparative Study of Topical 5-Aminolevulinic Acid Incubation Times in Photodynamic Therapy with Intense Pulsed Light for the Treatment of Inflammatory Acne

Dermatologic Surgery — Mon, 24 Aug 2009 23:00:00 +0100

Photodynamic therapy (PDT) with topical 5-aminolevulinic acid (ALA) is used for effective treatment of facial acne vulgaris. To determine which of two different incubation times (30 minutes and 3 hours) is more effective in PDT with intense pulsed light (IPL) for acne vulgaris. Twenty Korean subjects with moderate to severe acne were enrolled for a randomized, half-facial treatment study. Three sessions with short incubation with ALA plus IPL (30 minutes, n=9) or long incubation with ALA plus IPL (3 hours, n=11) on one side of the face and IPL alone on the other side were performed at 1-month intervals. All subjects showed improvement in inflammatory acne lesions after three sessions of ALA-PDT or IPL alone (p (Source: Dermatologic Surgery)

Photocarcinogenesis and toxicity of benzoyl peroxide in hairless mice after simulated solar radiation

Experimental Dermatology — Sat, 22 Aug 2009 23:00:00 +0100

Abstract: Topical benzoyl peroxide (BPO) gel has long been used to treat acne vulgaris and has recently been combined with clindamycin (BPO-clin). No skin malignancies have been reported after clinical use of BPO, but there has been concern about the possible carcinogenicity of BPO alone and in combination with UV radiation. BPO can promote skin tumorigenesis in a mouse skin chemical carcinogenesis model. As acne vulgaris is frequently localized on sun-exposed areas, we investigated whether BPO or BPO-clin accelerates photocarcinogenesis in combination with simulated solar radiation (SSR) in 12 groups of 25 hairless female C3.Cg/TifBomTac-immunocompetent mice. BPO or BPO-clin was applied topically to the back five times each week, followed by SSR three times each week (2, 3, or 4 standard ...

IBD Causation Expert Again Excluded From Accutane MDL

LexisNexis® Mealey's™ Emerging Drugs & Devices Legal News — Sat, 22 Aug 2009 10:35:48 +0100

TAMPA, Fla. - "Re-asserted" general causation testimony by plaintiff expert Dr. Ronald Fogel was excluded from the Accutane multidistrict litigation for a second time on Aug. 11 when a judge found that his opinion that the acne drug causes inflammatory bowel disease (IBD) still overreaches data on which it is based (In Re: Accutane Products Liability, MDL Docket No. 1626, No. 04-md-2523, M.D. Fla., Tampa Div.; See 3/5/09, Page 15). Full story on lexis.com (Source: LexisNexis® Mealey's™ Emerging Drugs & Devices Legal News)

FDA: Allergan Aczone ads were misleading

bizjournals.com Health Care:Industry Regulation headlines — Fri, 21 Aug 2009 19:36:25 +0100

The U.S. Food and Drug Administration on Friday released a letter to Allergan Inc. saying that the company’s marketing and advertising efforts for Aczone, an acne treatment, are misleading. (AGN) (Source: bizjournals.com Health Care:Industry Regulation headlines)

FDA: Allergan Aczone ads were misleading

bizjournals.com Health Care:Physician Practices headlines — Fri, 21 Aug 2009 19:36:25 +0100

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FDA: Allergan Aczone ads were misleading

bizjournals.com Health Care:Health Insurance headlines — Fri, 21 Aug 2009 19:36:25 +0100

FDA: Allergan Aczone ads were misleading

bizjournals.com Health Care:Pharmaceuticals headlines — Fri, 21 Aug 2009 19:36:25 +0100

FDA: Allergan Aczone ads were misleading

bizjournals.com Health Care:Biotechnology headlines — Fri, 21 Aug 2009 19:36:25 +0100

FDA: Allergan Aczone ads were misleading

bizjournals.com Health Care:Hospitals headlines — Fri, 21 Aug 2009 19:36:25 +0100

Japanese version of Cutaneous Body Image Scale: Translation and validation

The Journal of Dermatology — Thu, 20 Aug 2009 23:00:00 +0100

In this study, we translated the Cutaneous Body Image Scale (CBIS), a 7-item instrument originally created by Gupta et al. in 2004, into Japanese using a forward- and back-translation method and evaluated the reliability and validity of the instrument by psychometric tests. A total of 298 healthy adults (64 men and 234 women, aged 28.9 ± 9.9 years) and 165 dermatology patients (56.7% eczema/dermatitis, 9.8% acne, 7.5% alopecia, 6.9% psoriasis, 19.1% skin tumor/fleck/other) (30 men and 135 women, aged 37.9 ± 15.2 years) responded to the Japanese version of the CBIS. The internal-consistency reliability of the instrument was high (Cronbach's [alpha], healthy adults 0.88, patients 0.84). The CBIS measure demonstrates good test[ndash]retest reliability (healthy adults [gamma] = 0.92, P < 0.0...

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Single low-dose red light is as efficacious as methyl-aminolevulinate--photodynamic therapy for treatment of acne: clinical assessment and fluorescence monitoring.

Acta Derm Venereol A... — Thu, 20 Aug 2009 13:32:03 +0100

Authors: Hörfelt C, Stenquist B, Halldin CB, Ericson MB, Wennberg AM This controlled study investigated single low-dose red light photodynamic therapy and methyl-aminolevulinate (MAL) for treatment of moderate to severe facial acne in 19 patients. The right cheek was treated with MAL (160 mg/g) for 3 h prior to illumination. The left cheek received red light only. Both cheeks were illuminated with narrow-band red light (635 nm) at a light dose of 15 J/cm2. The global severity of acne was assessed at baseline and at follow-up, 10 and 20 weeks after treatment. Fluorescence images, clinical photographs and skin surface biopsies were obtained. Both MAL-photodynamic therapy and control areas showed a significant decrease in acne score at follow-up; no significant difference was found c...

Factors influencing the clinical evaluation of facial acne.

Acta Derm Venereol A... — Thu, 20 Aug 2009 13:32:03 +0100

Authors: Faure M, Pawin H, Poli F, Revuz J, Beylot C, Chivot M, Auffret N, Moyse D, Dréno B Existing scoring systems for facial acne focus on the lesions themselves, but clinical decisions are based on a general assessment of severity, including the time since onset, the site(s) of involvement, the patient's history, and the response to prior treatments. The aim of this study was to investigate the influence of some of these factors on the global assessment of acne severity. Involvement of the trunk, prior systemic treatment and a positive family history of acne increased the severity score. Inclusion of these factors could help to compose more homogeneous groups for clinical trials. PMID: 19688148 [PubMed - in process] (Source: Acta Derm Venereol A...)

Clinical and cosmeceutical uses of hydroxyacids

Clinics in Dermatology — Thu, 20 Aug 2009 10:16:02 +0100

Abstract: The hydroxyacids are represented by the α-hydroxyacids, β-hydroxyacids, polyhydroxy acids, and bionic acids. Together, these ingredients form a class of compounds with unparalleled benefits to the skin and unprecedented usage in the cosmeceutical market in cosmetic and therapeutic formulations alike. The most commonly used hydroxyacid is glycolic acid, an α-hydroxyacid that has been used extensively in cosmetic antiaging formulations, moisturizers, and peels, and in treatment products to improve hyperpigmentation and acne. The newer polyhydroxy and bionic acids offer the benefits of α-hydroxyacids without irritation, making them suitable for use on sensitive skin, rosacea, and after cosmetic procedures. They also provide additional antioxidant/chelation, barrier strengthening...

What you need to know about acne

Pulse Today Clinical Updates — Wed, 19 Aug 2009 09:47:00 +0100

Hospital practitioner in dermatology Dr Iain Henderson answers GP Dr Mandy Fry’s questions on retinoids, rosacea and the Pill (Source: Pulse Today Clinical Updates)

Discover the Powerful Benefits of Garlic

NaturalNews.com — Wed, 19 Aug 2009 07:00:00 +0100

(NaturalNews) Eating a clove of garlic might not be the tastiest snack in the world, but it will give you some powerful health benefits. Benefits include managing high cholesterol levels and decreasing the risk of various cancers. Garlic has been used for ages as a folk remedy for several diseases. Science is just now discovering how effective it really is in helping us become and stay healthy.Supports Cardiovascular System Over 250 publications have proven that garlic helps our cardiovascular system. It can lower cholesterol and triglyceride levels in your blood. Garlic can also inhibit platelet stickiness and increase fibrinolysis, which results in a decreased rate of blood coagulation. Anti-Microbial Properties Garlic may work against intestinal parasites because it has antibacterial, a...

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Pamidronate treatment in rheumatology practice: a comprehensive review

Clinical Rheumatology — Wed, 19 Aug 2009 00:44:46 +0100

This study aims to review the available published data regarding the potential use of pamidronate in rheumatology practice. Methods include the review of relevant articles retrieved by a PUBMED search utilizing the index term “pamidronate”. All available randomized control trials, open trials, and case series, as well as properly reported case studies evaluating usage of pamidronate in rheumatic disorders, have been included in the literature review. The efficacy of pamidronate in patients with spondyloarthropathies; synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome; hypertrophic osteoarthropathy; osteoporotic vertebral fractures; chronic back pain due to disk disease or spinal stenosis; Charcot arthropathy; transient osteoporosis; and complex regional pain syndrom...

SAPHO syndrome with adrenal deficiency: a case report

Cases Journal — Thu, 13 Aug 2009 23:00:00 +0100

Conclusion: The case presented here has the unique feature of adrenal deficiency presenting alongside the SAPHO syndrome and is presented as the first case reported. This syndrome could become complicated with different organ system involvement other than bone and skin. There is a need further studies that will explore the weak relationship between SAPHO syndrome and adrenal deficiency. (Source: Cases Journal)

Facing Facts About Acne

FDA Consumer Updates — Thu, 13 Aug 2009 19:38:00 +0100

Separating the facts from the myths can help people with acne treat the disease and keep it under control. (Source: FDA Consumer Updates)

Laser and Other Light Therapies for the Treatment of Acne Vulgaris: Systematic Review

Medscape Dermatology Headlines — Wed, 12 Aug 2009 20:12:30 +0100

What is the effectiveness of laser and other light therapies for acne? The British Journal of Dermatology (Source: Medscape Dermatology Headlines)

Guidelines for cryotherapy

Indian Journal of Dermatology, Venereology and Leprology — Wed, 12 Aug 2009 10:19:22 +0100

Sharma Vinod K, Khandpur SujayIndian Journal of Dermatology, Venereology, and Leprology 2009 75(8):90-100Introduction: Cryotherapy is a controlled and targeted destruction of diseased tissue by the application of low temperatures. It is a simple, cost-effective, efficacious and esthetically acceptable modality for the treatment of various dermatoses. Indications: It is indicated in the treatment of a wide variety of skin conditions, including benign tumors, acne, pigmented lesions, viral infections, inflammatory dermatoses, infectious disorders and various pre-malignant and malignant tumors. Facility: Cryosurgery is an out patient department proce...

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Chinese Herbs Treat Endometriosis Better Than Western Medicine

NaturalNews.com — Wed, 12 Aug 2009 07:00:00 +0100

(NaturalNews) Increasingly, Chinese herbal medicine (CHM) is being put to the test by Western scientists -- and the results are sometimes not only successful but downright astounding. A case in point: a new review of CHM research by British scientists just published in Cochrane Database of Systematic Reviews shows treating endometriosis with Chinese herbs may not only relieve symptoms of the disease, CHM appears to have comparable benefits to drugs and even laparoscopic surgery with fewer adverse effects.This is important news because endometriosis is a huge problem in the US and Western medicine has yet to come up with any viable treatment that doesn't have serious side effects. According to the National Institutes of Health (NIH), at least 5.5 million women in North America alone have th...

What Is Rosacea? What Causes Rosacea?

Dermatology News From Medical News Today — Tue, 11 Aug 2009 07:00:00 +0100

Rosacea is a chronic, inflammatory skin condition which principally affects the face. Rosacea causes facial redness and produces small, red, pus-filled pustules (bumps). Rosacea worsens with time if left untreated. It is often mistaken for acne or eczema, or some other skin allergy. According to Medilexicon's (Source: Dermatology News From Medical News Today)

Many U.S. teens share medications

CBC | Health — Mon, 10 Aug 2009 21:57:59 +0100

About 20 per cent of U.S. teens said they've lent or borrowed prescription medications such as antibiotics and acne medication, a new study suggests. (Source: CBC | Health)

40% Of US Teenagers Share Diverse Prescription Drugs, With Possibly Dangerous And Even Deadly Consequences

Health News from Medical News Today — Mon, 10 Aug 2009 08:00:00 +0100

Imagine one teenager who has acne giving some Accutane, a prescription medication, to a friend. The friend is pregnant and does not know it yet. Accutane is linked to birth defects. This kind of scenario among adolescents is much more common than people realize in the USA. (Source: Health News from Medical News Today)

Targeted treatment of pyoderma gangrenosum in PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome with the recombinant human interleukin-1 receptor antagonist anakinra

British Journal of Dermatology — Sun, 09 Aug 2009 23:00:00 +0100

We report the rapid and lasting response of pyoderma gangrenosum to the targeted treatment with the recombinant human interleukin-1 receptor antagonist (rHuIL-1Ra) anakinra in a patient with PAPA syndrome. (Source: British Journal of Dermatology)

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Targeted treatment of pyoderma gangrenosum in PAPA (pyogenic arthritis, pyoderma gangrenosum and acne) syndrome with the recombinant human interleukin-1 receptor antagonist anakinra.

The British Journal of Dermatology — Sun, 09 Aug 2009 23:00:00 +0100

Pro-Medics Now Stocking New Line of Acne Treatment Products

PRWeb: Medical Pharmaceuticals — Fri, 07 Aug 2009 11:32:52 +0100

Pro-medics.com, the online pharmacy has just announced their decision to stock a variety of prescription acne treatment medications due to growing pharmaceutical demand. (PRWeb Aug 7, 2009) Read the full story at http://www.prweb.com/releases/2009/08/prweb2720134.htm (Source: PRWeb: Medical Pharmaceuticals)

Acne vulgaris patients have low levels of anti-inflammatory IL-10

MedWire News - Dermatology — Fri, 07 Aug 2009 00:00:00 +0100

Acne vulgaris patients are unable to suppress early inflammatory changes due to defective immunosurveillance resulting from low levels of the anti-inflammatory interleukin-10, say researchers. (Source: MedWire News - Dermatology)

He Shou Wu is the Most Amazing Longevity Herb of All

NaturalNews.com — Thu, 06 Aug 2009 07:00:00 +0100

(NaturalNews) Out of about 10,000 Chinese medicinal plants only about 60 belong to the class of Superior Tonic Herbs. Out of these 60 herbs He Shou Wu is the most amazing longevity tonic of all. It is widely used in Chinese herbal medicine as a tonic to prevent premature aging by tonifying the Kidney and Liver functions. It also is known to bring up Jing (vital essence), nourishing the blood, and fortifying the muscles, tendons and bones. It strengthens and stabilizes the lower back and knees. He Shou Wu is also used to enhance sexual drive and fertility in men and women. It can increase sperm count in men and help build more semen even in old age. It helps build ova in women as well. It is also widely used in Asia to maintain the youthful condition and color of the hair. This is, for some...

Photodynamic therapy in dermatology: a review

Lasers in Medical Science — Tue, 04 Aug 2009 19:14:24 +0100

Abstract Photodynamic therapy (PDT) is used for the prevention and treatment of non-melanoma skin cancer. Until recently, clinically approved indications have been restricted to actinic keratoses, nodular and superficial basal cell carcinoma, and, since 2006, Bowen disease. However, the range of indications has been expanding continuously. PDT is also used for the treatment of non-malignant conditions such as acne vulgaris and leishmaniasis, as well as for treating premature skin aging due to sun exposure. The production of reactive oxygen intermediates like singlet oxygen depends on the light dose applied as well as the concentration and localization of the photosensitizer in the diseased tissue. Either cytotoxic effects resulting in tumor destruction or immunomodulatory ...

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Chlorhexidine prevents hypochlorous acid-induced inactivation of alpha-1-antitrypsin (alpha-1-AT).

Clinical and Experimental Pharmacology and Physiology — Mon, 03 Aug 2009 23:00:00 +0100

Authors: Montecucco F, Bertolotto M, Ottonello L, Pende A, Dapino P, Quercioli A, Mach F, Dallegri F 1. Chlorhexidine digluconate has been used as a topical antiseptic in the treatment of acne vulgaris and periodontitis. The acute phase of these diseases involves neutrophilic infiltration. Neutrophil activation and recruitment to inflammatory sites are crucial in both protection against bacterial infections and induction of hystotoxic damage. Activated neutrophils release several enzymes (elastase and myeloperoxidase [MPO]), which contribute to tissue injury through the direct toxic activity, the generation of oxidants and the inactivation of protective factors, such as alpha-1-antitrypsin (alpha-1-AT). In the present study, we investigated if chlorhexidine might modulate neutrophil-me...

Ciclosporin: Keloid acne: case report

Reactions — Mon, 03 Aug 2009 10:55:12 +0100

(Source: Reactions)

Chronic treatment with 13-cis-retinoic acid changes aggressive behaviours in the resident–intruder paradigm in rats

European Neuropsychopharmacology — Mon, 03 Aug 2009 00:00:00 +0100

Abstract: Retinoids, vitamin A related compounds, have an established role in the development of the nervous system and are increasingly recognized to play a role in adult brain function. The synthetic retinoid, 13-cis-retinoic acid (13-cis-RA, Roaccutane) is widely used to treat severe acne but has been linked to an increased risk of neuropsychiatric side effects, including depression. Here we report that chronic administration with 13-cis-RA (1mg/kg i.p. daily, 7–14days) in adult rats reduced aggression- and increased flight-related behaviours in the resident–intruder paradigm. However, in the forced swim, sucrose consumption and open field tests treatment for up to 6weeks with 13-cis-RA did not modify behaviour in adult or juvenile animals. The behavioural change observed in the res...

A mechanism-based classification of dermatologic reactions to biologic agents used in the treatment of cutaneous disease: Part 1.

Dermatitis — Fri, 31 Jul 2009 23:00:00 +0100

Authors: Bremmer M, Deng A, Gaspari AA Biologic therapies are an efficacious new method of controlling a number of chronic conditions. Data regarding these medications continues to emerge, giving clinicians a greater understanding of their side effects profiles. The biologic agents used in dermatology, particularly the tumor necrosis factor-alpha inhibitors, have a number of varied dermatologic side effects. In this two-part article, we perform a review of literature regarding the cutaneous side effects of infliximab, etanercept, adalimumab, rituximab, efalizumab, and alefacept. In Part 1, we will discuss cutaneous infections, malignancy, rebound phenomenon, eczema, atopic dermatitis, lichenoid reactions, granulomatous disease, pruritus, acne, and progressive multifocal leukoencephalop...

Congenital adrenal hyperplasia

Medicine — Fri, 31 Jul 2009 11:53:28 +0100

Abstract: Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder of adrenal steroid biosynthesis affecting 1/10,000 to 1/15,000 live births. The most common form is 21-hydroxylase deficiency due to mutations in the CYP21A2 gene. CAH classically presents at birth with ambiguous genitalia in an affected female. Salt loss, the only sign in an affected newborn male, affects the majority and can be life-threatening. An adolescent female with CAH has a syndrome of hirsutism, acne and irregular periods. Treatment aims to replace adequate amounts of glucocorticoid and mineralocorticoid hormones but avoid side effects such as growth suppression. Serum 17OH-progesterone is increased in CAH due to 21-hydroxylase deficiency and is a useful marker to monitor treatment. Surgery for ambi...

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Hormonal Therapies Offer Effective Solutions for Many Adult Women with Acne

MedlinePlus Health News — Thu, 30 Jul 2009 16:29:19 +0100

Source: American Academy of Dermatology Related MedlinePlus Topic: Acne (Source: MedlinePlus Health News)

Hormonal Therapies Offer Effective Solutions For Many Adult Women With Acne

Health News from Medical News Today — Thu, 30 Jul 2009 08:00:00 +0100

Although acne traditionally has been considered a disease of teenagers, it is also extremely common in adult women. Studies show that acne affects more than 50 percent of women between the ages of 20-29 and more than 25 percent of women between the ages of 40-49 (1). In fact, after age 20, women are far more likely to report having acne than men. (Source: Health News from Medical News Today)

Acne fulminans following measles infection

The Journal of Dermatology — Wed, 29 Jul 2009 23:00:00 +0100

(Source: The Journal of Dermatology)

NanoBio to Announce Key Preclinical Data on Nanoemulsions for the Treatment of Acne at American Academy of Dermatology Summer Meeting

Drugs.com - Clinical Trials — Wed, 29 Jul 2009 19:50:41 +0100

Data confirm bactericidal activity of NB-003 against P. acnes, suggest promise of nanoemulsions in topical acne therapy ANN ARBOR, Mich.--(BUSINESS WIRE)--Jul 29, 2009 - NanoBio Corp. today announced that it will present compelling new data... (Source: Drugs.com - Clinical Trials)

Hidradenitis suppurativa (acne inversa): early inflammatory events at terminal follicles and at interfollicular epidermis*

Experimental Dermatology — Tue, 28 Jul 2009 23:00:00 +0100

Please cite this paper as: Hidradenitis suppurativa (acne inversa): early inflammatory events at terminal follicles and at interfollicular epidermis. Experimental Dermatology 2009.Abstract: Hidradenitis suppurativa (acne inversa) is a chronic suppurative and scarring inflammatory disease with predilection in the apocrine gland-bearing areas. Histological investigations in the 1990s showed keratotic occlusion of the terminal follicle structure to be the initial cause. Our investigations describe and reproduce the morphology and try to figure out very early lesions of HS. A total of 262 operative specimens from 60 patients were investigated by routine histology and 11 operative specimens by immunohistochemistry: HS is dominated by a heterogeneous histological image. 82% of the surgical speci...

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Comparison of a 1,550 nm Erbium:Glass fractional laser and a chemical reconstruction of skin scars (CROSS) method in the treatment of acne scars: A simultaneous split-face trial

Lasers in Surgery and Medicine — Mon, 27 Jul 2009 23:00:00 +0100

Acne scarring is a common complication of acne but no effective single treatment modality has been developed. To compare the efficacy of 1,550 nm Er:Glass fractional laser and chemical reconstruction of skin scar (CROSS) method in the treatment of acne scars.A split-face trial was conducted in 20 patients (10 rolling, 10 icepick types) with acne scars. One side was treated with the 1,550 nm Er:Glass fractional laser three times with a 6-week interval. And the other side was treated with CROSS method two times every 12 weeks.Significant improvement was observed in both sides of the face. In rolling type, the objective and subjective improvement rates were significantly higher in the sides treated with laser than CROSS method. However, in icepick type, there were no statistically significant...

Medicis Announces Approval of New Strengths of SOLODYN(R)

Medical News (via PRIMEZONE) — Mon, 27 Jul 2009 20:05:00 +0100

SCOTTSDALE, Ariz., July 27, 2009 (GLOBE NEWSWIRE) -- Medicis (NYSE:MRX) today announced that the U.S. Food and Drug Administration (FDA) has approved additional strengths of SOLODYN(R) (minocycline HCl, USP) Extended Release Tablets in 65mg and 115mg dosages for the treatment of inflammatory lesions of non-nodular moderate to severe acne vulgaris in patients 12 years of age and older. (Source: Medical News (via PRIMEZONE))

Clearing Up The Mystery Of Adult Acne

Thu, 23 Jul 2009 18:05:35 +0100

Acne is a disease that can affect anyone beyond puberty, and it's the most prevalent skin condition in the United States, according to The American Academy of Dermatology, with almost 50 percent of adults suffering from some form of acne. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)

Zileuton prevents the activation of the leukotriene pathway and reduces sebaceous lipogenesis

Experimental Dermatology — Wed, 22 Jul 2009 23:00:00 +0100

In conclusion, zileuton prevents the activation of the leukotriene pathway and enhancement of lipogenesis by AA in human sebocytes in vitro. (Source: Experimental Dermatology)

[Original articles] Treatment of acne with oral isotretinoin in patients with cystic fibrosis

Archives of Disease in Childhood — Wed, 22 Jul 2009 23:00:00 +0100

Conclusions: Adolescents with cystic fibrosis and acne can be treated with oral isotretinoin. Oral isotretinoin should be considered for adolescents with cystic fibrosis who have acne associated with scarring, acne not clearing with topical and antibiotic treatment, acne associated with depression or severe cystic acne. (Source: Archives of Disease in Childhood)

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Original papers The role of benzoyl peroxide in prevention of development of antibiotic-resistant Propionibacterium acnes during combined treatment with erythromycin and tretinoin

Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house — Wed, 22 Jul 2009 10:22:25 +0100

The objectives of the study were to determine: (1) the prevalence of skin colonization by propionibacteria resistant to erythromycin among acne patients of the Spa Dermatological Clinic in Iwonicz Zdrój, (2) the development of antibiotic resistance during the 12-week treatment by different topical medications, (3) the role of topical benzoyl peroxide in prevention of development of antibiotic-resistant Propionibacterium acnes during combined treatment with erythromycin and tretinoin. Material and methods: Sixty patients of both sexes between the age of 16 and 26 suffering from mild to moderate acne (Leeds scale 2-6) were classified in 3 groups (20 in each). The first group was treated with topical 4% erythromycin, the second group with 4% erythromycin and 0.025% tretinoin, and the third g...

Risk of High-Grade Skin Rash in Cancer Patients Treated with Cetuximab - an Antibody against Epidermal Growth Factor Receptor: Systemic Review and Meta-Analysis.

Oncology — Tue, 21 Jul 2009 23:00:00 +0100

Conclusion: Cancer patients who received cetuximab have a substantial risk of developing high-grade skin rash. The risk may be particularly increased in patients with CRC. Further studies are strongly recommended for the prevention and treatment of high-grade skin rash. PMID: 19622903 [PubMed - as supplied by publisher] (Source: Oncology)

Review of Fractional Photothermolysis: Treatment Indications and Efficacy

Dermatologic Surgery — Sun, 19 Jul 2009 23:00:00 +0100

Fractional photothermolysis (FP) is one of the most significant milestones in laser technology and resurfacing. Review of the Medline English literature and recent international conferences regarding FP technology, applications, and indications. Successful conditions treated with nonablative FP reported in the literature include acne scarring; dyschromia and fine wrinkling of photoaging on the face, chest, neck, and hands; melasma; poikiloderma of Civatte; nevus of Ota; scars; minocycline hyperpigmentation; telangiectatic matting; residual hemangioma; granuloma annulare; colloid milium; and disseminated superficial actinic porokeratosis. An advance in 2007 was the introduction of ablative FP (AFP), which results in significantly greater improvement in skin laxity and textural abnormalities...

OBSERVATION: Cyclosporine-Induced Infantile Nodulocystic Acne

Archives of Dermatology — Sun, 19 Jul 2009 23:00:00 +0100

Conclusions Nodulocystic acne may be induced by the use of cyclosporine in children as well as adults. When it occurs, it can be managed with cessation of cyclosporine therapy and treatment with isotretinoin. Because this management approach may influence other outcomes in children with transplants, it is best to treat these patients using a multidisciplinary approach. (Source: Archives of Dermatology)

Interleukin-10 secretion from CD14+ peripheral blood mononuclear cells is downregulated in patients with acne vulgaris

British Journal of Dermatology — Sun, 19 Jul 2009 23:00:00 +0100

Conclusions These data suggest that patients with acne have a proinflammatory cytokine milieu and crucially are unable to contain early inflammatory changes due to a specific defect in immunosurveillance, namely low monocyte IL-10 production. Our observations raise the possibility that acne therapeutics might profitably target IL-10 both as a regulator of proinflammatory cytokines and in augmenting the CD14+ cell phagocytic response. (Source: British Journal of Dermatology)

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11. Acne, Psoriasis, and Disorders of Keratinization

Medical and Surgical Dermatology — Sat, 18 Jul 2009 17:11:29 +0100

Content Type Journal ArticleDOI 10.1007/s00533-009-0147-5 Journal Medical and Surgical DermatologyOnline ISSN 1934-2853Print ISSN 0944-5196 (Source: Medical and Surgical Dermatology)

Dolder Grand Zurich Switzerland

Telegraph Health — Fri, 17 Jul 2009 16:04:06 +0100

Spa Spy: Our health sleuth examines the curative claims of wellbeing retreats worldwide. (Source: Telegraph Health)

Tetracyclines: what a rheumatologist needs to know?

APLAR Journal of Rheumatology — Wed, 15 Jul 2009 23:00:00 +0100

This article will review the rheumatological use of tetracycline and its analogues. (Source: APLAR Journal of Rheumatology)

Treatment Options For Acne Patients Post Accutane's Withdrawal From US Market

Pharmaceutical Online News — Wed, 15 Jul 2009 08:43:00 +0100

Roche Holding AG, the world's biggest maker of cancer drugs, recently announced the withdrawal of its Accutane acne medicine from the US Market. (Source: Pharmaceutical Online News)

Skin Care in Ethnic Populations

Seminars in Plastic Surgery — Tue, 14 Jul 2009 10:49:15 +0100

Seminars in Plastic Surgery 2009; 23: 168-172DOI: 10.1055/s-0029-1224795ABSTRACTUse of over-the-counter cosmetics, approaches to hygiene, and many basic dermatologic principles differ between individuals with Caucasian skin and ethnic skin. Still, comparatively few publications highlight these variations or discuss appropriate management. Among many ethnic patients, issues related to skin hydration, restoration of even pigmentation, hair removal, and acne care remain problematic yet not fully addressed. As well, there are some dermatologic conditions that may be rare in Caucasian skin but are much more common in the ethnic patient. Here, we discuss various aspects of skin hydration, dyschromia, sunscreen use, and chemical depilatories in the ethnic population.[...]© Thieme Medical Publish...

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Heat-killed Propionibacterium acnes is capable of inducing inflammatory responses in skin

Experimental Dermatology — Mon, 13 Jul 2009 23:00:00 +0100

Please cite this paper as: Heat-killed Propionibacterium acnes is capable of inducing inflammatory responses in skin. Experimental Dermatology 2009.Abstract: The etiology of acne is a complex process, and acne is one of the most common skin disorders affecting millions of people. The pathogenesis of acne is closely associated with the bacterium, Propionibacterium acnes which was previously known as Corynebacterium parvum. Both viable and non-viable P. acnes/C. parvum have been shown to induce an immunostimulatory effect in vivo, suggesting that even dead bacteria continue to activate an inflammatory response. Acne treatments with lasers or devices, induce a bactericidal effect through heat generation which may not address the immunogenic activity of P. acnes and the resulting acne inflamma...

Amineptine: Acne: case report

Reactions — Mon, 13 Jul 2009 10:50:06 +0100

(Source: Reactions)

Why Does He Have Such a Dry Mouth?

PediatricEducation.org — Mon, 13 Jul 2009 00:01:48 +0100

Discussion Saliva is produced mainly from the submandibular salivary glands (70-75%) and the parotid gland (20-25%). It functions to protect the mouth, aid digestion, maintain tooth integrity and facilitate chewing, swallowing and speech. Dry mouth or xerostomia especially in children is usually a temporary condition often associated with dehydration or mouth breathing. But it can be a more chronic condition that can affect quality of life and overall health. Patients with chronic xerostomia may stop eating certain dry or sticky foods which may lead to malnutrition. It can also change taste, and impair chewing, swallowing, and swallowing. It can also cause fissures in the skin or oral mucosa and contribute to dental caries and other oral infections. Children with multiple medical problem...

Amineptine: Acne: case report.

Reactions Weekly — Sat, 11 Jul 2009 10:50:03 +0100

Page: 7 (Source: Reactions Weekly)

MedWorm: Acne

SAPHO syndrome: is a range of pathogen-associated rheumatic diseases extended?

Acne: Causes, treatment and prevention

Too old for acne? At 30, Rebecca thought she was past the age for spots

Skin Tightening Effect Using Fractional Laser Treatment: I. A Randomized Half-Side Pilot Study on Faces of Patients with Acne

Fractional CO2 laser: a novel therapeutic device upon photobiomodulation of tissue remodeling and cytokine pathway of tissue repair

Effaclar Acne Spot Treatment

Personalized OTC Acne Care

Sun Defense Kit for Acne-Prone Skin

Benzoyl peroxide and adapalene fixed combination: a novel agent for acne.

ACG: Acne Drug Tied to IBD (CME/CE)

Acne vulgaris und Seborrhoe, Rosacea, Psoriasis vulgaris, Parapsoriasis, Lupus erythematodes

Uncommon etiology of an anterior chest wall mass.

The individual health burden of acne: Appearance-related distress in male and female adolescents and adults with back, chest and facial acne

Acne in women: clinical patterns in different age-groups

Management of acne vulgaris: an evidence-based update

Immune reconstitution inflammatory syndrome involving the skin

Uncommon Etiology of an Anterior Chest Wall Mass [CASE REPORTS]

With Microdermabrasion, Rough Seems to Work Better

RESEARCH LETTERS: Physician Workforce for Acne Care in the United States, 2003 Through 2005

Physician Workforce for Acne Care in the United States, 2003 Through 2005 [Research Letters]

Dusa targets skin cancer to blunt downturn’s effects

Dusa targets skin cancer to blunt downturn’s effects

A case of SAPHO syndrome with destructive spondylodiscitis suspicious of tuberculous spondylitis

II. Zur Kenntnis der Pathogenese der Perifolliculitis capitis abscedens et suffodiens (E. Hoffmann) und ihrer Beziehungen zur Acne conglobata

Natural remedies for acne

Quality of Sexual Life in Hyperandrogenic Women Treated with an Oral Contraceptive Containing Chlormadinone Acetate

New Study Assesses Skin Hydration And Epidermal Function Of 2.5% And 5% Benzoyl Peroxide-Clindamycin Combinations

Effect of konjac glucomannan hydrolysates and probiotics on the growth of the skin bacterium Propionibacterium acnes in vitro

Antibiotics Control SAPHO Syndrome, but Symptoms Recur When Therapy Stops

New insights into synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome

Nicotinamide inhibits Propionibacterium acnes-induced IL-8 production in keratinocytes through the NF-κB and MAPK pathways

Nonbacterial osteitis: a clinical, histopathological, and imaging study with a proposal for protocol-based management of patients with this diagnosis

11. Acne, Psoriasis, and Disorders of Keratinization

50 years ago from the Connecticut State Medical Journal. October 1959. Radiation therapy of acne.

Photodynamic therapy of acne vulgaris using 5-aminolevulinic acid 0.5% liposomal spray and intense pulsed light in combination with topical keratolytic agents

[Pandalao and skin whitening in Mayotte.]

Multimodal Treatment of Acne, Acne Scars and Pigmentation

Nonablative Fractional Laser Resurfacing

Emerging Technologies in Aesthetic Medicine

Health advice: 'Is there a cure for a son who's uncommunicative and sullen?'

Fact Checking Anecdotes: Obama Wrong On Particulars In Cancer And Acne Insurance Denial Case

Cervical and Vulvar Intraepithelial Neoplasia after Treatment with Oral Isotretinoin for Severe Acne Vulgaris

Fractional photothermolysis—an update

FACT CHECK: In health debate, Obama's stories of hardship don't always hold up to scrutiny

Management of cutaneous side-effects of cetuximab therapy in patients with metastatic colorectal cancer

Birth control pills for acne?

Birth control pills for acne?

Efficacy of antibiotic therapy for SAPHO syndrome is lost after its discontinuation: interventional study

OBSERVATION: Interaction of Topical Sulfacetamide and Topical Dapsone With Benzoyl Peroxide

Poor diet may increase risk for acne in adolescent girls

Teen Acne and Depression: Can Mood Worsen Skin?

Poor diet may increase risk for acne in adolescent girls

Efficacy and safety profiles of cetuximab in Chinese patients with colorectal cancer

Acne Really Is A Nightmare For Some Teens

Less chocolate, more veggies may help acne

Is the association between acne and mental distress influenced by diet? Results from a cross-sectional population study among 3775 late adolescents in Oslo, Norway.

Acne really is a nightmare for some teens

Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report

Acne: guide to features and recommended management

Expression of tumor necrosis factor-alpha converting enzyme and matrix metalloproteinase-3 in proliferated synovium in a patient with synovitis-acne-pustulosis-hyperostosis-osteitis syndrome: a case report

Depressive symptoms and suicidal ideation during isotretinoin treatment: a 12-week follow-up study of male Finnish military conscripts. - Rehn L, Meririnne E, Höök-Nikanne J, Isometsä E, Henriksson M.

Treatment of Acne Rosacea Reviewed

XXIV.Ueber den Primäraffect der Acne, des Gesichtslupus, des Lepra und anderer Krankheiten der Lymphcapillaren

Weight-based dosing: Extended-release minocycline efficient, predictable

Cutaneous remodeling and photorejuvenation using radiofrequency devices

The <i> 'Holi' </i> dermatoses : Annual spate of skin diseases following the spring festival in India

Prevalence of depression, its correlates among students, and its effect on health-related quality of life in a Turkish university.

Fractional 1320 nm Nd : YAG laser in the treatment of acne vulgaris: a pilot study

Elevated Testosterone and Hypergonadotropism in Active Adolescents of Normal Weight with Oligomenorrhea

[Skin manifestations, treatment and rehabilitation in overweight and obesity.]

Family history linked to acne in teens

Teens Fight Acne Before School Starts

Specific gel-cream as adjuvant to oral isotretinoin improved hydration and prevented TEWL increase – a double-blind, randomized, placebo-controlled study

Treating PIH: Combination therapies appropriate for troublesome condition

[Facial dystrophic calcinosis cutis secondary to acne.]

Should dermatologists prescribe hormonal contraceptives for acne?

FDA warns Allergan on Aczone promotion

Treatment options for acne rosacea.

[Short-term efficacy of cetuximab combined with radiotherapy or chemotherapy on head and neck cancer: a report of 11 cases.]