MedWorm: Back Curves

Restoration of lordosis and disk height after single‐level transforaminal lumbar interbody fusion

Orthopaedic Surgery — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Intervertebral height and lumbar lordosis reconstruction are important for achieving good surgical results; guidance regarding the likely changes in lumbar lordosis and disk height after TLIF is provided by our findings. (Source: Orthopaedic Surgery)

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Evaluation of vertical traction radiography for predicting the outcome of moderate to severe rigid scoliosis correction

Orthopaedic Surgery — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Traction radiographic imaging is an effective, feasible preoperative assessment for determining which vertebrae are stable, designing the surgical strategy and choosing the UIV and LIV for correcting moderate to severe, rigid scoliosis. (Source: Orthopaedic Surgery)

The accuracy of active shape modelling and end-plate measurements for characterising the shape of the lumbar spine in the sagittal plane.

Computer Methods in Biomechanics and Biomedical Engineering — Mon, 30 Jan 2012 07:54:13 +0100

Authors: Ali AH, Cowan AB, Gregory JS, Aspden RM, Meakin JR Abstract The 2D shape of the lumbar spine in the sagittal plane can be determined from lordosis angles measured between the corresponding end-plates of the vertebral bodies or by using an active shape model (ASM) of the vertebral body outline. The ASM was previously shown to be a more efficient and reliable method, but its accuracy has not been assessed. The aim of this study was to determine the accuracy of an ASM for characterising lumbar spine shape and compare this to conventional measurements. Images of 25 different lumbar spine shapes were generated and measured, using both methods, by three independent observers. The accuracy of the ASM, determined from lordosis angles predicted by the model, was found to be better ...

Surgical treatment of the spinal stenosis with an interspinous distraction device: do we really restore the foraminal height?

Turkish Neurosurgery — Mon, 30 Jan 2012 05:00:02 +0100

CONCLUSION: Using the Coflex device is a minimal invasive, effective and safe procedure. Restoration of the foraminal height may not be a responsible factor for clinical improvement. We think microsurgical decompression looks responsible of the good clinical outcome and using interspinous device is unnecessary. Comparative clinical studies can be informative. PMID: 22274971 [PubMed - in process] (Source: Turkish Neurosurgery)

15. Intraoperative monitoring of evoked potentials in scoliosis surgery at University Hospital Brno

Clinical Neurophysiology — Sat, 28 Jan 2012 16:42:18 +0100

Aim: The aim of our study was the evaluation of sensitivity and specificity of intraoperative monitoring (IOM) of evoked potentials (EP) in scoliosis and developmental spinal deformities surgery in our hospital. (Source: Clinical Neurophysiology)

Physical capacity of girls with mild and moderate idiopathic scoliosis: influence of the size, length and number of curvatures (Czaprowski et al.)

European Spine Journal — Wed, 25 Jan 2012 06:53:23 +0100

Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00586-012-2165-7Authors Vijayakumar Palaniswamy, Physiotherapy Programme, School of Rehabilitation Science, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 Kuala Lumpur, MalaysiaSrijit Das, Department of Anatomy, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 Kuala Lumpur, Malaysia Journal European Spine JournalOnline ISSN 1432-0932Print ISSN 0940-6719 (Source: European Spine Journal)

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Single‐nucleotide polymorphism in Turkish patients with adolescent idiopathic scoliosis: Curve progression is not related with MATN‐1, LCT C/T‐13910, and VDR BsmI

Journal of Orthopaedic Research — Wed, 25 Jan 2012 05:00:00 +0100

In this study, we investigated the relationship between AIS and polymorphisms in MATN‐1, LCT C/T‐13910, and VDR BsmI genes. 53 Turkish adolescents with diagnosed AIS and 54 healthy adult individuals were included in the study. MATN‐1, LCT C/T‐13910, and VDR BsmI gene mutations were analyzed with real‐time PCR. We did not detect a statistically significant difference between AIS and control groups in respect to those three different gene polymorphisms (p < 0.05). We next evaluated the associations of all three SNPs with scoliosis curve severity. There was no significant difference between curve severity and gene polymorphisms (p < 0.05). In terms of gene polymorphisms, AIS patients with a family history of AIS did not significantly differ from AIS patients who did no...

Physical Therapy Intervention Studies on Idiopathic Scoliosis - Review with the focus on Inclusion Criteria *

Scoliosis — Wed, 25 Jan 2012 05:00:00 +0100

Conclusion: There is no outcome paper on PT in scoliosis with a patient sample at risk for being progressive in adults or in adolescents followed from premenarchial status until skeletal maturity. However, papers on bracing are more frequently found and bracing can be regarded as evidence-based in the conservative management and rehabilitation of idiopathic scoliosis in adolescents. (Source: Scoliosis)

Anterior short correction in thoracic adolescent idiopathic scoliosis with mini-open thoracotomy approach: prospective clinical, radiological and pulmonary function results

European Spine Journal — Tue, 24 Jan 2012 18:15:28 +0100

Conclusion A good deformity correction without loss of correction or adding on, a good cosmetic result and good patient’s satisfaction were achieved through shorter than end-to-end thoracic fusions. The radiological residual deformity is acceptable. Anterior correction of thoracic scoliosis with a short spinal fusion is recommended to keep the large part of the spine mobile. A very short fusion, small thoracotomy incision, low-profile implants and complete closure of parietal pleura are keys to prevent reduction in postoperative lung function. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-012-2156-8Authors Kan Min, Department of Orthopaedics, Balgrist Clinic, University of Zurich, Forchstrasse 340, 8008 Zurich, SwitzerlandMathi...

Relationship of the lumbar lordosis angle to the abdominal aortic bifurcation and inferior vena cava confluence levels

Clinical Anatomy — Tue, 24 Jan 2012 05:00:00 +0100

This study showed that the level of bifurcation of the aorta and the level of confluence of the IVC may vary with the variations of the LLA. Clin. Anat. 2012. © 2012 Wiley Periodicals, Inc. (Source: Clinical Anatomy)

Smartphone aided measurement of spinal deformity proves superior to manual methods

ICMCC: The International Council on Medical and Care Compunetics — Sun, 22 Jan 2012 11:03:36 +0100

Source: Tim Bredrup, iMedicalApps Content: “Certain smartphone applications can provide quick assistance in the diagnosis of disease. One such example is Cobbmeter, a smartphone application designed for the measurement of Cobb angle on Apple’s iPhone. The Cobb angle measures the degree of spinal deformity which exists in a person with scoliosis. In efforts to [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)

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2011 SOSORT Guidelines: Orthopaedic and Rehabilitation Treatment of Idiopathic Scoliosis During Growth

Scoliosis — Fri, 20 Jan 2012 05:00:00 +0100

Conclusion: These Guidelines have been a big effort of SOSORT to paint the actual situation of CTIS, starting from the evidence, and filling all the gray areas using a scientific method. According to results, it is possible to understand the lack of research in general on CTIS. SOSORT invites researchers to join, and clinicians to develop good research strategies to allow in the future to support or refute these recommendations according to new and stronger evidence. (Source: Scoliosis)

TDT-HET: A new transmission disequilibrium test that incorporates locus heterogeneity into the analysis of family-based association data

BMC Bioinformatics - Latest articles — Fri, 20 Jan 2012 05:00:00 +0100

Conclusions: We have developed an extension of the TDT statistic (TDT-HET) that allows for locus heterogeneity among coded trios. Benefits of our method include: estimates of parameters in the presence of heterogeneity, and reasonable power even when the proportion of linked trios is small. Also, we have extended multi-locus methods to TDT-HET and have demonstrated that the empirical power may be high to detect linkage. Last, given that we obtain PPBs, we conjecture that the TDT-HET may be a useful method for correctly identifying linked trios. We anticipate that researchers will find this property increasingly useful as they apply next-generation sequencing data in family based studies. (Source: BMC Bioinformatics - Latest articles)

All-pedicle-screw versus hybrid hook-screw instrumentation for posterior spinal correction surgery in adolescent idiopathic scoliosis: a curve flexibility matched-pair study

Archives of Orthopaedic and Trauma Surgery — Wed, 18 Jan 2012 07:00:49 +0100

Conclusions All-pedicle-screw and hybrid hook-screw instrumentations are comparable with regard to curve correction, but all-pedicle screw instrumentation reduces blood loss during surgery and shortens the operation time, which may help shorten healing time. Content Type Journal ArticleCategory Orthopaedic Outcome AssessmentPages 1-7DOI 10.1007/s00402-011-1454-7Authors Changwei Yang, Department of Orthopedics, Changhai Hospital, Shanghai, 200433 People’s Republic of ChinaXianzhao Wei, Department of Orthopedics, Changhai Hospital, Shanghai, 200433 People’s Republic of ChinaJiahao Zhang, Foreign Guest Hospital Ward, Huashan Hospital, Shanghai, People’s Republic of ChinaDajiang Wu, Department of Orthopedics, Changhai Hospital, Shanghai, 200433 People’s Republic ...

Lumbar spine and total-body dual-energy X-ray absorptiometry in children with severe neurological impairment and intellectual disability: a pilot study of artefacts and disrupting factors

Pediatric Radiology — Wed, 18 Jan 2012 06:48:44 +0100

Conclusion Factors that may negatively influence the accuracy of DXA outcome are frequently present in children with severe neurological impairment and ID. No systematic deviation of DXA outcome in coherence with the amount of disrupting factors was found, but physicians should be aware of the possible influence of disrupting factors on the accuracy of DXA. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00247-011-2307-9Authors S. Mergler, Intellectual Disability Medicine/Department of General Practice, Erasmus University Medical Centre, PO Box 2040, 3000 CA, Rotterdam, The NetherlandsR. Rieken, Intellectual Disability Medicine/Department of General Practice, Erasmus University Medical Centre, PO Box 2040, 3000 CA, Rotterdam, The Netherla...

Biomechanical Evaluation of Predictive Parameters of Progression in Adolescent Isthmic Spondylolisthesis: a computer modeling and simulation study

Scoliosis — Wed, 18 Jan 2012 05:00:00 +0100

Conclusions: Progression of the slippage is mostly affected by a movement and an increase of stresses at the lumbosacral junction in accordance with spino-pelvic parameters. The statistical results provide evidence that pelvic incidence is a predictive parameter to determine progression in isthmic spondylolisthesis. (Source: Scoliosis)

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Scoliosis short-term rehabilitation (SSTR) according to 'Best Practice' standards - are the results repeatable?

Scoliosis — Tue, 17 Jan 2012 05:00:00 +0100

Conclusion: Out-patient rehabilitation following the Scoliologic (TM) 'Best Practice' standards seems to provide an improvement of signs and symptoms of scoliosis patients in this study using a pre- / post prospective design. The results of the pilot study therefore seem to be repeatable. (Source: Scoliosis)

Toward deconstructing the phenotype of late‐onset Pompe disease

American Journal of Medical Genetics Part C: Seminars in Medical Genetics — Tue, 17 Jan 2012 05:00:00 +0100

We describe in detail 44 patients diagnosed with late‐onset Pompe disease (LOPD) at our neuromuscular department from 1985 to 2011 and compare them to patients with LOPD in the literature of the past 40 years. Study of the Munich LOPD group revealed varying musculoskeletal and cardio‐cerebrovascular manifestation patterns. Several of these symptom patterns commonly appeared in conjunction with one another, highlighting the multisystem involvement of this condition. Common symptom patterns include: (i) Classic limb girdle and diaphragmatic weakness, (ii) rigid spine syndrome (RSS), scoliosis, and low body mass, and (iii) several cardio‐cerebrovascular manifestation patterns. The most common presentation, limb girdle and diaphragmatic weakness, appeared in 78% (34/44) of our patients a...

Now is the perfect time to schedule your child's yearly physical

Pediatric Health Associates — Mon, 16 Jan 2012 20:41:00 +0100

Kim GubbinsCertified Pediatric Nurse PractitionerWant to beat the rush? Now is the best time to get your child’s physical/annual checkup completed! Why wait until the summer ‘check-up’ crowd. Scheduling it now gives you the opportunity to schedule an appointment when it's convenient for you.The American Academy of Pediatrics (AAP) and PHA recommend that all children have an annual well child exam even if a physical form is not needed for sports or school that particular year. This visit will include a history of what is going on in the child's life, developmental screening (autism screening at 18 and 24 months), a physical examination, possible laboratory tests (such as hemoglobin, lead, cholesterol or a urinalysis) or vaccinations. There w...

R2 Predicting Scores for Left Ventricular Dysfunction in Duchenne Muscular Dystrophy

Pediatrics International — Mon, 16 Jan 2012 05:00:00 +0100

Conclusion: Our scoring system detects the early heart dysfunction of DMD patients, especially when BNP level is not elevated. This system is useful to determine the timing for echocardiographic examination and consulting cardiologists.© 2012 The Authors. Pediatrics International © 2012 Japan Pediatric Society (Source: Pediatrics International)

Defining Thoracic Kyphosis in Patients with Pectus Excavatum

Journal of Surgical Research — Sat, 14 Jan 2012 22:30:12 +0100

(Source: Journal of Surgical Research)

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An Evaluation of Medium-term Outcomes of Thoracoscopic Congenital Diaphragmatic Hernia Repair in Neonates and Infants

Journal of Surgical Research — Sat, 14 Jan 2012 22:29:59 +0100

Introduction: Thoracoscopic repair of congenital diaphragmatic hernia (CDH) has become more widespread. Our previous study demonstrated improved short term outcomes with minimally invasive surgical (MIS) repair of CDH, including quicker return to enteral nutrition, shorter duration of narcotic use, and fewer major complications. the current study evaluates medium term outcomes of neonatal thoracoscopic CDH repair compared to open repair. Methods: Institutional review board approval was obtained to analyze data from our neonatal surgical registry to study patients under six months of age who underwent CDH repair from January 2003 to July 2011. Patients with Morgagni's defects, inadequate records, or traumatic diaphragmatic hernias were excluded. Demographic, operative details and follow-up ...

Anterior Reconstruction With Nano-hydroxyapatite/polyamide-66 Cage After Thoracic and Lumbar Corpectomy.

Orthopedics — Sat, 14 Jan 2012 15:24:05 +0100

Authors: Yang X, Song Y, Liu L, Liu H, Zeng J, Pei F Abstract Cages are used to regain stability of the anterior spinal column following vertebrectomy, which could prevent significant donor-site morbidity from the iliac autograft harvesting and the risk of disease transmission associated with the allograft. The hollow, porous, cylindrical nanohydroxyapatite/polyamide 66 (n-HA/PA66) cage is a new nonmetallic cage device made by combining nanohydroxyapatite with polyamide 66. Few studies have examined its effectiveness and outcomes over a follow-up >2 years.We retrospectively studied 51 consecutive patients with acute traumatic thoracic or lumbar burst fracture who underwent anterior reconstruction with the n-HA/PA66 cage following single-level corpectomy. Radiologic parameters (r...

A Kohonen neural network description of scoliosis fused regions and their corresponding Lenke classification

International Journal of Computer Assisted Radiology and Surgery — Fri, 13 Jan 2012 16:56:09 +0100

Conclusion The Lenke classification and fusion region agree in the majority of adolescent idiopathic scoliosis when reviewed retrospectively. The results indicate the need for spinal fixation instrumentation variation associated with the Lenke classification. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s11548-011-0667-0Authors N. Mezghani, Laboratoire de recherche en imagerie et orthopédie, École de technologie supérieure Centre de recherche du CHUM, Hôpital Notre-Dame, 1560 rue Sherbrooke Est, local Y-1615, Montreal, QC H2L 4M1, CanadaP. Phan, Research Center, Sainte-Justine University Hospital Center, Montreal, QC, CanadaA. Mitiche, Institut National de la Recherche Scientifique, INRS-EMT, Montreal, QC, CanadaH. Labelle, Department...

Serum cartilage metabolites as biomarkers of degenerative lumbar scoliosis

Journal of Orthopaedic Research — Fri, 13 Jan 2012 05:00:00 +0100

AbstractSeveral biomarkers have been used to evaluate osteoarthritis of the limb joints. Here we evaluated the use of serum cartilage metabolites as biomarkers for degenerative lumbar scoliosis (DLS). Fifty‐two DLS patients with Cobb angle > 10° were compared with 19 control patients. Serum levels of hyaluronic acid (HA), keratan sulfate (KS), cartilage oligomeric matrix protein (COMP), collagen type II cleavage (C2C), and procollagen type II C‐propeptide (CPII) were measured. Serum levels of KS (DLS 1.20 ± 0.44 µg/ml vs. control 0.98 ± 0.33 µg/ml), CPII (DLS 1905.1 ± 948.2 ng/ml vs. control 1223.6 ± 884.4 ng/ml), and C2C (DLS 219.1 ± 59.2 ng/ml vs. control 177.7 ± 71.7 ng/ml) were significantly higher in DLS. There were no significan...

Intervertebral focal surgery for the treatment of non-contiguous multifocal spinal tuberculosis

International Orthopaedics — Thu, 12 Jan 2012 06:43:13 +0100

Conclusions Intervertebral focal surgery by complete debridement, deformity correction, graft fusion, and internal fixation for patients with non-contiguous multifocal spinal tuberculosis was feasible and effective. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00264-011-1478-1Authors Jian-Dang Shi, Department of Spinal Surgery, General Hospital of Ningxia Medical University, 804 Shengli Street, Xingqing District, Yinchuan, 750004 Ningxia, People’s Republic of ChinaZi-Li Wang, Department of Spinal Surgery, General Hospital of Ningxia Medical University, 804 Shengli Street, Xingqing District, Yinchuan, 750004 Ningxia, People’s Republic of ChinaGuang-Qi Geng, Department of Spinal Surgery, General Hospital of Ningxia Medical University, 80...

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Symptomatic Heterozygotes and Prenatal Diagnoses in a Nonconsanguineous Family with Syndromic Combined Pituitary Hormone Deficiency Resulting from Two Novel LHX3 Mutations.

The Journal of Clinical Endocrinology and Metabolism — Wed, 11 Jan 2012 05:00:00 +0100

Conclusions:This study of the first nonconsanguineous patient with LHX3 mutations demonstrates the pleiotropic roles of LHX3 during development and its full involvement in the complex disease phenotype. Isolated limitation of head rotation may exist in heterozygous carriers and would result from a dominant-negative effect. These data allowed the first prenatal diagnoses of this severe condition to be performed. PMID: 22238406 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism)

Multilevel oblique corpectomy for cervical spondylotic myelopathy preserves segmental motion

European Spine Journal — Tue, 10 Jan 2012 16:59:55 +0100

Conclusions The OCC preserves segmental motion in the short-term, however, the tendency towards straightening of the spine, albeit without clinical worsening, warrants serial follow-up imaging to determine whether this motion preservation is long lasting. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-011-2137-3Authors Ari George Chacko, Section of Neurosurgery, Department of Neurological Sciences, Christian Medical College, Vellore, 632004 Tamil Nadu, IndiaMathew Joseph, Section of Neurosurgery, Department of Neurological Sciences, Christian Medical College, Vellore, 632004 Tamil Nadu, IndiaMazda Keki Turel, Section of Neurosurgery, Department of Neurological Sciences, Christian Medical College, Vellore, 632004 Tamil Nadu, IndiaKris...

Kyphotic deformity in spinal tuberculosis and its management

International Orthopaedics — Tue, 10 Jan 2012 16:59:43 +0100

Abstract Spinal tuberculosis is the most common cause of severe kyphosis in many parts of the world. Three percent of patients treated conservatively end up with a deformity greater than 60 degrees which can cause serious cosmetic, psychological, cardio-respiratory and neurological problems. Severe kyphotic deformities are usually the result of childhood spinal deformities and ‘Spine at risk’ radiological signs are helpful to identify children at risk of deformity. In children, a severe type of collapse, termed as ‘Buckling Collapse’ is also noted where the kyphosis is more than 120 degrees. Risk factors for buckling collapse include an age of less than seven years at the time of infection, thoracolumbar involvement, loss of more than two vertebral bodies and t...

Scoliosis after thoracotomy/sternotomy in children with congenital heart disease

Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1) — Tue, 10 Jan 2012 05:00:00 +0100

Conclusion: Scoliosis is not a common finding among the operated children with CHD in our center. (Source: Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1))

Visual loss after spine surgery

Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1) — Tue, 10 Jan 2012 05:00:00 +0100

We report one-year follow up of a 50-years-old hypertensive housewife who underwent lumbar decompression and fusion for degenerative scoliosis, but woke up with painless unilateral visual loss. Fundus examination was normal. Her visual acuity improved from initial finger counting close to face to finger counting at 3 m at 1 year. Identification of high risk patients may help in appropriate preoperative counselling, prevention and early recognition of this devastating complication. (Source: Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1))

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Adverse effects of growth hormone replacement therapy in children

Arquivos Brasileiros de Endocrinologia e Metabologia — Sun, 08 Jan 2012 19:33:01 +0100

Human growth hormone (hGH) replacement therapy has been widely available for clinical purposes for more than fifty years. Starting in 1958, hGH was obtained from cadaveric pituitaries, but in 1985 the association between hGH therapy and Creutzfeldt-Jakob disease was reported. In the same year, the use of recombinant hGH (rhGH) was approved. Side effects of rhGH replacement therapy in children and adolescents include rash and pain at injection site, transient fever, prepubertal gynecomastia, arthralgia, edema, benign intracranial hypertension, insulin resistance, progression of scoliosis, and slipped capital femoral epiphysis. Since GH stimulates cell multiplication, development of neoplasms is a concern. We will review the side effects reported in all rhGH indications.A terapia de reposiç...

C2 lamina reconstruction using locking miniplate for the intradural tumor of the craniocervical junction (two case reports)

European Spine Journal — Sat, 07 Jan 2012 16:55:50 +0100

Conclusions This procedure results in rigid fixation of the reimplanted C2 lamina and helps to restore the paraspinous muscles. For these reasons, it appears to be a useful surgical procedure for spinal tumors requiring C2 laminectomy and does not cause postoperative kyphosis of the cervical spine. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00586-011-2138-2Authors Hisanori Ikuma, Department of Orthopaedic Surgery, Kagawa Rosai Hospital, 3-3-1 Joto-cho, Marugame, Kagawa 763-8502, JapanKensuke Shinohara, Department of Orthopaedic Surgery, Kagawa Rosai Hospital, 3-3-1 Joto-cho, Marugame, Kagawa 763-8502, JapanTakashi Maehara, Department of Orthopaedic Surgery, Kagawa Rosai Hospital, 3-3-1 Joto-cho, Marugame, Kagawa 763-8502, JapanYoshiki Yoko...

The impact of segmental and en bloc derotation maneuvers on scoliosis correction and rib prominence in adolescent idiopathic scoliosis.

Journal of Neurosurgery.Spine — Fri, 06 Jan 2012 05:00:00 +0100

Conclusions Although each surgical technique of DBVD may have theoretical benefits and risks, no apparent difference in outcomes was observed between techniques. The concurrent use of both techniques was associated with increased blood loss and operative duration without any appreciable benefit. The surgeon should adopt the derotation technique with which he or she is most comfortable, but concurrent use of both does not appear to improve results. PMID: 22225489 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)

The surgical treatment and related management for post-tubercular kyphotic deformity of the cervical spine or the cervico-thoracic spine

International Orthopaedics — Wed, 04 Jan 2012 06:48:05 +0100

Conclusion One-stage anterior debridement, instrumentation and fusion for cervical spinal TB and single posterior instrumentation for cervico-thoracic spinal TB followed by chemotherapy is practical to correct PTK. The procedure has the advantage of lower blood loss, effective kyphosis correction and minimal complications. To patients with severe deformity, skeletal traction seemed indispensible. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00264-011-1438-9Authors Yang Liu, Orthopedics Research Institute of the Chinese People’s Liberation Army, Orthopedics Department of Changzheng Hospital, Changzheng, ChinaYuanyuan Chen, Orthopedics Research Institute of the Chinese People’s Liberation Army, Orthopedics Department of Changzheng Hosp...

A rare case of life-threatening giant plexiform schwannoma

The Spine Journal — Tue, 03 Jan 2012 05:00:00 +0100

A 28-year-old woman with idiopathic scoliosis presented with a cervical mass and progressive gait disturbance over the course of 2 years. Examination demonstrated mild spastic paraplegia, hypoesthesia with upper level at T5 and severe respiratory failure requiring assisted ventilation. Magnetic resonance imaging showed multiple thoracic masses compressing left lung, trachea, and spinal cord (). Surgical resection was performed. Through C5–T1 laminectomy, the intradural part of the neoplasia was completely removed, and the extradural part was enucleated as much as possible. After surgery, the respiratory function improved. Histologic pattern and S100 protein diffuse reactivity were consistent with plexiform schwannoma, a rare benign cutaneous variation of schwannoma . Although deep-seated...

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Commentary: Postoperative spinal alignment remodeling in Lenke 1C scoliosis treated with selective thoracic fusion

The Spine Journal — Sun, 01 Jan 2012 05:00:00 +0100

COMMENTARY ON: Wang Y, Bünger CE, Zhang Y, et al. Postoperative spinal alignment remodeling in Lenke 1C scoliosis treated with selective thoracic fusion. Spine J 2012;12:73–80 (in this issue). (Source: The Spine Journal)

Heritability of scoliosis. Grauers A, Rahman I, Gerdhem P. Eur Spine J 2011 Nov 18. [Epub ahead of print]

The Spine Journal — Sun, 01 Jan 2012 05:00:00 +0100

To estimate the heritability of scoliosis in the Swedish Twin Registry. Self-reported data on scoliosis from 64,578 twins in the Swedish Twin Registry were analysed. Prevalence, pair- and probandwise concordances and tetrachoric correlations in mono- and dizygotic same-sex twins were calculated. The relative importance of genetic variance, i.e. the heritability, and unique and shared environmental variance was estimated using structural equation modelling in Mx software. In addition, all twins in the twin registry were matched against the Swedish Inpatient Register on the primary diagnosis idiopathic scoliosis. (Source: The Spine Journal)

Positioning of the patient during shoulder surgery: an inexpensive, safe and easy technique

European Journal of Orthopaedic Surgery and Traumatology — Fri, 30 Dec 2011 16:42:13 +0100

Abstract The knowledge of shoulder pathology has improved tremendously in the last decades, and shoulder surgery is increasingly performed because of new treatment options and better operative results. Nowadays most surgical shoulder procedures are performed in the sitting or semi-sitting (beach chair) position. Stability of the patient and the ability to flex, extend and rotate the shoulder during surgery are crucial to improve exposure of the surgical field and lower the risk of perioperative complications. We developed an easy, safe and inexpensive surgical set-up providing a very good posterior, superior and anterior access to the shoulder in the sitting or semi-sitting position. In this technique, the patient is placed supine with the head at the foot end of the table...

Weight-height ratios and parameters of body posture in 7-9-year-olds with particular posture types.

Ortopedia, Traumatologia, Rehabilitacja — Fri, 30 Dec 2011 05:00:00 +0100

Conclusions. The inclination angle of the lumbosacral spine, total curvature length, position of the apex of lordosis relative to S1, and S1-PL length (length of lordosis), appeared to be the least helpful in differentiating among postural types. PMID: 22248464 [PubMed - in process] (Source: Ortopedia, Traumatologia, Rehabilitacja)

Two level cervical corpectomy with iliac crest fusion and rigid plate fixation: a retrospective study with a three-year follow-up.

Turkish Neurosurgery — Thu, 29 Dec 2011 18:00:03 +0100

CONCLUSION: Excellent fusion rates can be achieved following two-level corpectomy with iliac bone graft repacement. This techique is easy, cost effective and safe. If the bone graft is harvested from the iliac crest by standart approach and between anatomical landmarks, most patients do not experience persistent pain at the donor site. PMID: 22194123 [PubMed - in process] (Source: Turkish Neurosurgery)

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Startup targeting spinal deformity raises $2.5M

bizjournals.com Health Care:Pharmaceuticals headlines — Wed, 28 Dec 2011 20:23:14 +0100

Med-tech startup KSpine Inc., which has developed a device for treating spinal disorders, has raised $2.5 million in capital, according to a regulatory filing. The Minnetonka-based firm is targeting the market for treating scoliosis, according to a report in MedCity News. Patients suffering from the condition have curved spines. KSpine’s technology would be used to correct the curvature during surgery. KSpine plans to put its recently won funding toward clinical trials, a company official told MedCity News... (Source: bizjournals.com Health Care:Pharmaceuticals headlines)

Cage subsidence does not, but cervical lordosis improvement does affect the long-term results of anterior cervical fusion with stand-alone cage for degenerative cervical disc disease: a retrospective study

European Spine Journal — Wed, 28 Dec 2011 16:51:52 +0100

Conclusions The results suggest that the clinical and radiological outcomes of the stand-alone titanium box cage for the surgical treatment of one- or two-level degenerative cervical disc disease are satisfactory. Cage subsidence does not exert significant impact upon the long-term clinical outcome although it is common for the stand-alone cages. The cervical lordosis may be more important for the long-term clinical outcome than cage subsidence Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00586-011-2131-9Authors Wen-Jian Wu, Department of Orthopedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, 1665 Kongjiang Road, 200092 Shanghai, ChinaLei-Sheng Jiang, Department of Orthopedic Surgery, Xinhua Hospital, Sh...

Pathomechanics of Gowers' Sign: A Video Analysis of a Spectrum of Gowers' Maneuvers.

Clinical Orthopaedics and Related Research — Wed, 28 Dec 2011 05:00:00 +0100

CONCLUSIONS: The classically described Gowers' sign is usually a late finding. However more subtle forms of Gowers' sign including mild hand pressure against the thigh and prone crawl position should be recognized by clinicians to initiate additional diagnostic tests. LEVEL OF EVIDENCE: Level III, diagnostic study. See the Guidelines for Authors for a complete description of levels of evidence. PMID: 22203329 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)

A clinical study of internal fixation, debridement and interbody thoracic fusion to treat thoracic tuberculosis via posterior approach only

International Orthopaedics — Tue, 27 Dec 2011 17:03:00 +0100

Conclusions This approach can successfully remove the focus of tuberculosis with complete interbody thoracic fusion after operation, which restores spinal stability. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00264-011-1449-6Authors Hongqi Zhang, Department of Spine Surgery, Xiangya Spinal Surgery Center, Xiangya Hospital of Central South University, Changsha, 410008 People’s Republic of ChinaShu Huang, Department of Spine Surgery, Xiangya Spinal Surgery Center, Xiangya Hospital of Central South University, Changsha, 410008 People’s Republic of ChinaHubing Guo, Department of Spine Surgery, Xiangya Spinal Surgery Center, Xiangya Hospital of Central South University, Changsha, 410008 People’s Republic of ChinaLei Ge, Department of Sp...

Towards determining soft tissue properties for modelling spine surgery: current progress and challenges

Medical and Biological Engineering and Computing — Sat, 24 Dec 2011 16:45:55 +0100

Abstract Current complication rates for adolescent scoliosis surgery necessitate the development of better surgical planning tools to improve outcomes. Here we present our approach to developing finite element models of the thoracolumbar spine for deformity surgery simulation, with patient-specific model anatomy based on low-dose pre-operative computed tomography scans. In a first step towards defining patient-specific tissue properties, an initial ‘benchmark’ set of properties were used to simulate a clinically performed pre-operative spinal flexibility assessment, the fulcrum bending radiograph. Clinical data for ten patients were compared with the simulated results for this assessment and in cases where these data differed by more than 10%, soft tissue properties fo...

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Mutations in the notch pathway alter the patterning of multifidus.

Anatomical Record — Sat, 24 Dec 2011 01:47:08 +0100

Authors: Fisher RE, Smith HF, Kusumi K, Tassone EE, Rawls A, Wilson-Rawls J Abstract Clinical studies have suggested that defects in the epaxial muscles, particularly multifidus, may contribute to the etiology of idiopathic scoliosis. While the epaxial muscles and the vertebrae derive from the same embryonic segmentation process, the mechanisms that pattern the multisegmental back muscles are still unclear. The process of segmentation is regulated by the Notch signaling pathway, and mutations in the modulators delta-like 3 (Dll3) and lunatic fringe (Lfng) are genetic models for spinal disorders such as scoliosis. Osteological defects have been characterized in these genetic models, but myological phenotypes have not previously been studied. We analyzed the multifidus muscle in the ...

Growth hormone supplement treatment reduces the surgical risk for Prader–Willi Syndrome patients

European Spine Journal — Fri, 23 Dec 2011 06:47:23 +0100

Conclusion There were no severe complications such as deep infections or neurovascular damage. A few obese patients underwent surgery, but there were no dangerous complications. Overall, we consider that GH treatment before surgery may reduce postoperative complications. The growing rod method was effective for PWS patients who resisted brace treatment owing to mental retardation. Content Type Journal ArticleCategory Case ReportPages 1-9DOI 10.1007/s00586-011-2110-1Authors Yutaka Nakamura, Department of Orthopedic Surgery, Dokkyo Medical University Koshigaya Hospital, 2-1-50 Minami-Koshigaya, Koshigaya, Saitama 343-8555, JapanToshiro Nagai, Department of Pediatrics, Dokkyo Medical University Koshigaya Hospital, 2-1-50 Minami-Koshigaya, Koshigaya, Saitama 343-8555, J...

Case presentation: abdominal compartment syndrome complicating posterior spinal fusion

Pediatric Anesthesia — Fri, 23 Dec 2011 05:00:00 +0100

We present the case of an 8‐year‐old child with Duchenne muscular dystrophy (DMD) undergoing correction of a severe scoliotic curvature. Near the end of an otherwise unremarkable surgery, he developed severe respiratory compromise associated with respiratory acidosis, hypoxia, and hypotension in the face of a catastrophic decrease in lung compliance. After supine positioning and examination, he was discovered to have ACS, which was treated with laparotomy. Complete recovery occurred after 5 days. This case report should raise awareness of a rare, life threatening, but imminently treatable entity that can accompany scoliosis surgery. The description of this case should be particularly important for pediatric anesthesiologists and orthopedic surgeons who care for patients undergoing co...

Associations between matrilin-1 gene polymorphisms and adolescent idiopathic scoliosis curve patterns in a Korean population.

Molecular Biology Reports — Fri, 23 Dec 2011 05:00:00 +0100

In this study, we examined whether the susceptibility to AIS is associated with MATN1 gene polymorphisms in a Korean population, which included 166 individuals with AIS and 126 controls. We found that there were no statistically significant associations between any of the MATN1-linked allele or genotype frequencies between AIS and controls. However, statistically significant associations were found at single nucleotide polymorphism (SNP) rs1065755 when comparing the curve patterns of AIS with the controls. The A allele of SNP rs1065755 was associated with a higher risk of AIS than the allele G in the genotype-phenotype (curve pattern) analysis (P = 0.029). In addition, the frequency of the A allele of SNP rs1065755 in AIS with double major curves was higher than in controls (P = 0.021,...

Kyphoscoliosis associated with congenital neuromuscular disease with uniform type 1 fibers

European Spine Journal — Thu, 22 Dec 2011 12:50:27 +0100

Conclusion Spinal deformity in CNMDU1 has a risk of severe progression, which makes early diagnosis by biopsy important. The surgery may be recommended before severe progression of spinal deformity and respiratory disorder. Perioperative MH is a concern, but can be managed by appropriate procedures. Content Type Journal ArticleCategory Case ReportPages 1-6DOI 10.1007/s00586-011-2128-4Authors Shiro Imagama, Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65, Tsurumai, Showa-ku, Nagoya, Aichi 466-8550, JapanNoriaki Kawakami, Department of Orthopaedic Surgery and Spine Center, Meijo Hospital, 1-3-1, Sannomaru, Naka-ku, Nagoya, Aichi 460-0001, JapanTaichi Tsuji, Department of Orthopaedic Surgery and Spine Center, Meijo Hospital, 1-3-1, ...

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Roles for Oestrogen Receptor β in Adult Brain Function

Journal of Neuroendocrinology — Thu, 22 Dec 2011 08:02:06 +0100

Oestradiol exerts a profound influence upon multiple brain circuits. For the most part, these effects are mediated by oestrogen receptor (ER)α. We review here the roles of ERβ, the other ER isoform, in mediating rodent oestradiol‐regulated anxiety, aggressive and sexual behaviours, the control of gonadotrophin secretion, and adult neurogenesis. Evidence exists for: (i) ERβ located in the paraventricular nucleus underpinning the suppressive influence of oestradiol on the stress axis and anxiety‐like behaviour; (ii) ERβ expressed in gonadotrophin‐releasing hormone neurones contributing to oestrogen negative‐feedback control of gonadotrophin secretion; (iii) ERβ controlling the offset of lordosis behaviour; (iv) ERβ suppressing aggressive behaviour in males; (v) ERβ modulating ...

Differences in deformity and bracing-related stress between rural and urban area patients with adolescent idiopathic scoliosis treated with a Cheneau brace.

Annals of Agricultural and Environmental Medicine : AAEM — Thu, 22 Dec 2011 05:00:00 +0100

Authors: Misterska E, Głowacki M, Ignyś-O'Byrne A, Latuszewska J, Lewandowski J, Ignyś I, Krauss H, Piątek J Abstract The aim of the study was to compare the difference in stress levels between adolescent female groups of patients from urban and rural areas who were treated conservatively with an idiopathic scoliosis. The study comprised 2 groups of patients, 34 from an urban and 30 from a rural area, with a minimum application of a Cheneau brace for 12 hours a day, for a minimum of 1 month. Two study groups completed the Polish version of both Bad Sobernheim Stress Questionnaire-Deformity and Bad Sobernheim Stress Questionnaire-Brace. Both groups of patients felt moderate stress connected with conservative treatment and low stress related to trunk deformation. No difference wa...

Protection of the remaining spinal cord function with intraoperative neurophysiological monitoring during paraparetic scoliosis surgery: a case report

Journal of Clinical Monitoring and Computing — Wed, 21 Dec 2011 20:05:40 +0100

Conclusions Intraoperative neurophysiological monitoring should be used for neuromuscular scoliosis cases with paraparesis if proximal function, such as the rectus femoris muscle, exists. Content Type Journal ArticlePages 1-4DOI 10.1007/s10877-011-9325-xAuthors Zhengyong Chen, 2025 Morse Ave, Neurology 2G, Sacramento, CA 95825, USAJoel Lerman, Department of Orthopaedics, Shriners Hospitals for Children-Northern California, 2425 Stockton Blvd, Sacramento, CA 95817, USA Journal Journal of Clinical Monitoring and ComputingOnline ISSN 1573-2614Print ISSN 1387-1307 (Source: Journal of Clinical Monitoring and Computing)

Comparison between two pedicle screw augmentation instrumentations in adult degenerative scoliosis with osteoporosis

BMC Musculoskeletal Disorders — Wed, 21 Dec 2011 05:00:00 +0100

Conclusion: Both augmentation pedicle screw with Polymethylmethacrylate (PMMA) and autogenous bone treating degenerative lumbar scoliosis combined with osteoporosis can achieve a good surgical result. Less oral pain medicines taken are the potential benefits of Polymethylmethacrylate augmentation, but that is at the cost of more medical spending. (Source: BMC Musculoskeletal Disorders)

Molecular cloning and expression analysis of xpd from zebrafish (Danio rerio).

Molecular Biology Reports — Wed, 21 Dec 2011 05:00:00 +0100

In this study we isolated the zebrafish cDNA encoding xpd, and examined its spatial-temporal expression during early development as well as its tissue distribution in adult zebrafish. Only one gene was identified in zebrafish and its sequence analysis showed a molecular structure with 23 coding exons similar to other species. The amino acid sequences were also found to be largely conserved among all species analyzed, suggesting function maintenance throughout evolution. Gene expression analysis in different zebrafish tissues by qPCR showed xpd expression in all tissues examined with the highest expression in branchial arches. Analysis of xpd expression in zebrafish embryos showed maternal inheritance and presence of xpd transcripts in all developmental stages analyzed suggesting its implic...

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Micropuncture Needles Combined with Ultrasound Guidance for Unusual Central Venous Cannulation: Desperate Times Call for Desperate Measures. A New Trick for Old Anesthesiologists.

Anesthesia and Analgesia — Tue, 20 Dec 2011 05:00:00 +0100

Authors: Castillo D, McEwen DS, Young L, Kirkpatrick J Abstract Central vascular access can be a very challenging task in patients with skeletal deformities such as ankylosing spondylitis, kyphosis, and chin-on-chest deformity. The use of traditional methods of accessing the central venous circulation in these patients can require multiple attempts and may lead to significant complications such as bleeding, pneumothorax, and vascular injury. Ultrasound-guided central venous access has become a very common procedure in the United States and Europe; its efficacy and safety have been demonstrated, and together with the use of micropuncture needles, the technique can facilitate central venous access in complicated cases. PMID: 22190551 [PubMed - as supplied by publisher] (Source: A...

Epidemiological survey of idiopathic scoliosis and sequence alignment analysis of multiple candidate genes

International Orthopaedics — Mon, 19 Dec 2011 16:52:59 +0100

Conclusion IS is a multifactorial genetic disease and SH3GL1 may be one of the pathogenic genes for IS. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00264-011-1419-zAuthors Tao Yang, Department of Orthopaedic, Southwest Hospital, Third Military University, No. 30 Gaotanyanzhengjie RAOD, Shapingba District, Chongqing 400038, ChinaQuanzhang Jia, Department of Orthopaedic, Southwest Hospital, Third Military University, No. 30 Gaotanyanzhengjie RAOD, Shapingba District, Chongqing 400038, ChinaHong Guo, Department of Orthopaedic, Southwest Hospital, Third Military University, No. 30 Gaotanyanzhengjie RAOD, Shapingba District, Chongqing 400038, ChinaJianzhong Xu, Department of Orthopaedic, Southwest Hospital, Third Military University, No. 30 Gaota...

Development of a smart garment to reduce kyphosis during daily living

Medical and Biological Engineering and Computing — Sat, 17 Dec 2011 17:04:09 +0100

Abstract Many of the aches and pains of adults are the result of the long-term effects of bad posture or body misalignment. Postural kyphosis in adolescence, which is an excessive rounding of the upper spine, may be one of the effects of poor standing and sitting habits. A smart garment, consisting of a harness and two data-sensor loggers, was developed to monitor and provide vibration feedback to wearers to improve their posture during daily activities. Laboratory tests verified that the garment could provide an accuracy of 2 ± 2° during static measurement and 3 ± 2° during stable or slowly changing posture activities and 4 ± 4° during rapidly changing posture activities. Four volunteers wore the system for 3 h per day and for 4 con...

The assessment of the postoperative spinal alignment: MRI adds up on accuracy

European Spine Journal — Sat, 17 Dec 2011 06:44:22 +0100

Conclusion Thoracal kyphosis measurement of postoperative spines in MRI is a valid diagnostic tool with reliability comparable to that of X-ray. These results cannot be transferred to lumbar lordosis measurement and transferred only partly to coronal COBB angle measurement. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00586-011-2115-9Authors Peter Bernstein, Department of Orthopaedic Surgery, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, Fetscherstr. 74, 01307 Dresden, GermanySusanne Hentschel, Department of Orthopaedic Surgery, University Hospital Carl Gustav Carus Dresden, Technical University Dresden, Fetscherstr. 74, 01307 Dresden, GermanyIvan Platzek, Department of Radiology, University Hospital “Ca...

Influence of transforaminal lumbar interbody fusion procedures on spinal and pelvic parameters of sagittal balance

European Spine Journal — Sat, 17 Dec 2011 06:44:20 +0100

Conclusion Single-level circumferential fusion helps patients reducing their pelvic compensation, but the amount of correction does not allow for complete correction of sagittal imbalance. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00586-011-2124-8Authors Mourad Ould-Slimane, Orthopaedic Surgery Department, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Paris-VII University, 100, Boulevard du général Leclerc, 92110 Clichy, FranceThibaut Lenoir, Orthopaedic Surgery Department, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Paris-VII University, 100, Boulevard du général Leclerc, 92110 Clichy, FranceCyril Dauzac, Orthopaedic Surgery Department, Beaujon Hospital, Assistance Publique-Hôpitaux de Paris, Paris-VII...

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Complication of cemented vertebra after kyphoplasty in osteoporotic compression fracture

European Journal of Orthopaedic Surgery and Traumatology — Thu, 15 Dec 2011 16:51:34 +0100

Abstract The reported case is of a postmenopausal woman with kyphoplasty for an L1 osteoporotic compression fractures (OCF) presenting with progressive kyphosis and paraparesis that developed with no history of other traumas. Serial radiographs and computed tomography were performed, followed by magnetic resonance (MR) imaging. On serial radiographs, local kyphosis and neurologic deficit progressed with collapse of the cemented vertebra. MR scan and histologic examination diagnosed avascular necrosis (AVN). The symptoms resolved after posterior vertebral column resection of the collapsed cemented vertebral body and correction of the deformity. Although kyphoplasty is a simple and safe procedure for the management of pain in OCFs, careful follow-up is required as collapse o...

Three-staged correction of severe rigid idiopathic scoliosis using limited halo-gravity traction

European Spine Journal — Tue, 13 Dec 2011 06:57:44 +0100

Conclusions Limited halo-gravity traction is an efficient, safe modality in the treatment of severe rigid adolescent scoliosis. The application of gradual traction over a limited period of 2 weeks led to better correction, shorter operative time with no significant complications. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-011-2111-0Authors Wael Koptan, Orthopaedic Department, Faculty of Medicine, Cairo University, Cairo, EgyptYasser ElMiligui, Orthopaedic Department, Faculty of Medicine, Cairo University, Cairo, Egypt Journal European Spine JournalOnline ISSN 1432-0932Print ISSN 0940-6719 (Source: European Spine Journal)

Anterior Elongation as a Minimally Invasive Alternative for Sagittal Imbalance—A Case Series

HSS Journal — Mon, 12 Dec 2011 17:06:18 +0100

This study aims to report a minimally invasive lateral approach using hyperlordotic cages in the treatment of mild sagittal imbalance. Radiological correction, clinical improvement, and safety will be analyzed. Methods Eight patients (mean age 71.8 years, SD 7.8; mean BMI 27.5, SD 2.3) with symptomatic sagittal imbalance were retrospectively reviewed. Eight cases were treated by anterior interbody fusion with lordotic cages. A minimally invasive lateral retroperitoneal approach was used in the surgical procedures, with or without percutaneous pedicle screw supplementation. Results No major complications occurred and just one case needed revision for direct decompression. Clinical outcomes Visual Analog Scale score changed from 88 at preopera...

Axial Lumbosacral Interbody Fusion Appears Safe as a Method to Obtain Lumbosacral Arthrodesis Distal to Long Fusion Constructs

HSS Journal — Mon, 12 Dec 2011 17:06:17 +0100

Conclusions The axial lumbosacral interbody fusion is a minimally invasive and safe method to obtain lumbosacral fixation and arthrodesis distal to a long fusion construct. Longer follow-up of larger numbers of patients are needed prior to recommending this procedure as a routine method to fuse L4–5 or L5–S1. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s11420-011-9227-yAuthors Paul S. Issack, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USAOheneba Boachie-Adjei, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA Journal HSS JournalOnline ISSN 1556-3324Print ISSN 1556-3316 (Source: HSS Journal)

Infections after spinal correction and fusion for spinal deformities in childhood and adolescence

International Orthopaedics — Sat, 10 Dec 2011 16:55:51 +0100

Conclusion Deep wound infection after instrumented fusion of the spine remains a difficult and challenging clinical problem and entails substantial morbidity, cost, and recovery time for the patient. An aggressive approach to deep wound infection emphasising early irrigation and debridement allowed preservation of instrumentation and successful fusion in most cases. At the conclusion of treatment, patients can expect a medium-term clinical outcome similar to patients in whom infectious complication did not occur. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00264-011-1439-8Authors Manon Bachy, Department of Paediatric Orthopaedics, Armand Trousseau Hospital, Pierre and Marie Curie University Paris 6, 26 avenue du Dr Arnold Netter, 75571...

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Postoperative infections of the lumbar spine: presentation and management

International Orthopaedics — Fri, 09 Dec 2011 17:04:20 +0100

Conclusions Risk factors for SSI include: 1) factors related to the nature of the spinal pathology and the surgical procedure and 2) factors related to the systemic health of the patient. Staphylococcus aureus is the most common infectious organism in reported series. Proven methods to prevent SSI include prophylactic antibiotics, meticulous adherence to aseptic technique and frequent release of retractors to prevent myonecrosis. The presentation of SSI is varied depending on the virulence of the infectious organism. Frequently, increasing pain is the only presenting complaint and can lead to a delay in diagnosis. Magnetic resonance imaging and the use of C-reactive protein laboratory studies are useful to establish the diagnosis. Treatment of SSI is centered on surgical d...

Effects of functional electrical stimulation on trunk control in children with diplegic cerebral palsy.

Disability and Rehabilitation — Fri, 09 Dec 2011 05:00:00 +0100

Conclusion: We believe to provide balance in sitting for children with CP, FES applied on abdomen-back muscles along with conventional therapy to maintain trunk control is more effective than conventional therapy alone. [Box: see text]. PMID: 22149464 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)

Spinal posterior movement after posterior cervical decompression surgery: clinical findings and factors affecting postoperative functional recovery.

Orthopedics — Thu, 08 Dec 2011 22:48:02 +0100

This study investigated the posterior movement of the spinal cord after posterior decompression surgery and evaluated factors affecting postoperative functional recovery in patients with cervical spondylotic myelopathy (CSM). Thirty-two patients with CSM underwent posterior decompression from C3 to C7 through laminectomy (n=12) and single, open-door laminoplasty (n=20). There were no significant differences between laminectomy and laminoplasty in degree of spinal posterior movement, recovery rate, and curvature index. Japanese Orthopedic Association (JOA) scores improved from preoperative (10.63±1.77; range, 7-14) to 3-months postoperative (13.57±1.50; range, 11-16) (n=32, P<.05) and from preoperative (10.24±1.87; range, 7-14) to 6-months postoperative (14.16±1.54; range, 12-16) (n=...

Whole-body MRI in neurofibromatosis: incidental findings and prevalence of scoliosis

Skeletal Radiology — Tue, 06 Dec 2011 17:04:00 +0100

Conclusions Incidental findings in the neurofibromatoses frequently involve the skeleton. Given the relatively high incidence of unsuspected osteonecrosis and stress fractures, close attention to the skeleton on WBMRI is advised. In addition, knowledge of common incidental findings can help clinicians prepare patients who undergo WBMRI for potential unexpected findings. Content Type Journal ArticleCategory Scientific ArticlePages 1-7DOI 10.1007/s00256-011-1333-xAuthors Jacob L. Jaremko, Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Yawkey 6E, 55 Fruit Street, Boston, MA 02114, USAPeter J. MacMahon, Musculoskeletal Imaging and Intervention, Department of Radiology, Massachusetts General H...

Is the pleth variability index a surrogate for pulse pressure variation in a pediatric population undergoing spine fusion?

Pediatric Anesthesia — Tue, 06 Dec 2011 05:00:00 +0100

Conclusions: Our data indicate that PVI is not a surrogate for PPV. PVI measurements were not influenced by changing from the supine to prone position and therefore may prove useful for patients undergoing spine surgery. (Source: Pediatric Anesthesia)

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Postoperative spinal alignment remodeling in Lenke 1C scoliosis treated with selective thoracic fusion

The Spine Journal — Mon, 05 Dec 2011 05:00:00 +0100

Conclusions: Selective thoracic fusion is prone to cause leftward spinal imbalance in Lenke 1C scoliosis patients. Postoperative spinal alignment remodeling can facilitate recovery of spinal balance in some patients. Postoperative spinal imbalance in Lenke 1C scoliosis patients could be prevented by selecting stable vertebra or the vertebrae above as LIV, checking the balance condition during surgery, or considering ratio criteria when selecting candidates for selective thoracic fusion. (Source: The Spine Journal)

[Clinical Picture] Spinal tuberculosis

LANCET — Sat, 03 Dec 2011 05:00:00 +0100

A 48-year-old Surinamese woman presented with a 1-year history of arthralgia. She had longstanding back pain following childhood traumatic injury. She had had no recent increase in back pain. She had no fever, malaise, weight loss, or coughing. Physical examination showed kyphosis at the thoracolumbar junction. No neurological abnormalities nor evidence of arthritis were noted. Radiography of the vertebral column () showed a severe kyphosis at the thoracolumbar junction (Th12–L1); multiple calcified mesenteric lymph nodes were seen. (Source: LANCET)

The prevalence of thoracolumbar kyphosis in achondroplasia: a systematic review

Journal of Children's Orthopaedics — Fri, 02 Dec 2011 17:29:33 +0100

Conclusions The prevalence rates of TLK in achondroplasia could not be assessed from the literature because the populations differed and the definition of TLK in the studies was not described. In future studies, this definition needs to be given and patients need to be assessed over a longer period of time, with repeated assessments. Content Type Journal ArticleCategory Original Clinical ArticlePages 1-5DOI 10.1007/s11832-011-0378-7Authors Alexander C. Engberts, Department of Neurosurgery, Leiden University Medical Center (LUMC), P.O. Box 9600, 2300 RC Leiden, The NetherlandsWilco C. H. Jacobs, Department of Neurosurgery, Leiden University Medical Center (LUMC), P.O. Box 9600, 2300 RC Leiden, The NetherlandsSanne J. A. M. Castelijns, Department of Orthopaedics, Univ...

Clinical characteristics and surgical outcome of the symptomatic ossification of ligamentum flavum at the thoracic level with combined lumbar spinal stenosis

Archives of Orthopaedic and Trauma Surgery — Fri, 02 Dec 2011 17:29:22 +0100

Conclusion Thoracic OLF with LSS will show a more severe clinical manifestation than that without LSS. In this study, we clearly indicated that the coexisting LSS in thoracic OLF will have adverse effects on the surgical results in thoracic OLF. Content Type Journal ArticleCategory Orthopaedic SurgeryPages 1-6DOI 10.1007/s00402-011-1438-7Authors Yoshihiro Matsumoto, Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 JapanKatsumi Harimaya, Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582 JapanToshio Doi, Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3-1...

Adolescent idiopathic scoliosis (AIS), environment, exposome and epigenetics: A molecular perspective of postnatal normal spinal growth and the etiopathogenesis of AIS with consideration of a network approach and possible implications for medical therapy

Scoliosis — Fri, 02 Dec 2011 05:00:00 +0100

Genetic factors are believed to play an important role in the etiology of adolescent idiopathic scoliosis (AIS). Discordant findings for monozygotic (MZ) twins with AIS show that environmental factors including different intrauterine environments are important in etiology, but what these environmental factors may be is unknown. Recent evidence for common chronic non-communicable diseases suggests epigenetic differences may underlie MZ twin discordance, and be the link between environmental factors and phenotypic differences. DNA methylation is one important epigenetic mechanism operating at the interface between genome and environment to regulate phenotypic plasticity with a complex regulation across the genome during the first decade of life. The word exposome refers to the totality of en...

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Lumbar fractures involving five vertebrae: a case report.

Journal of Orthopaedic Surgery — Thu, 01 Dec 2011 05:00:00 +0100

We report a 20-year-old man who sustained lumbar fractures involving 5 vertebrae following a road traffic accident. He was initially treated non-operatively to allow multiple pedicles to heal. He developed post-traumatic kyphosis for which corrective osteotomy and posterior spinal instrumented fusion was performed. He achieved a good functional outcome. We emphasise the need for careful radiological evaluation in patients with high-energy trauma, and the option of treating such complex injuries by non-operative means. If post-traumatic kyphosis develops, it can be dealt with later and the most mobile segments of the lumbar spine can be preserved. PMID: 22184180 [PubMed - in process] (Source: Journal of Orthopaedic Surgery)

A diagnostic classification for lumbar spine registry development

The Spine Journal — Thu, 01 Dec 2011 05:00:00 +0100

Conclusions: This study demonstrates that improved diagnostic stratification of lumbar spine disorders is a feasible goal. The diagnostic coding matrix, based on clinically relevant descriptors, yielded substantial interrater consistency for symptoms, moderate interrater consistency for structural and compressive pathology, and substantial intrarater consistency for all elements. (Source: The Spine Journal)

Neurologic deficit following lateral lumbar interbody fusion

European Spine Journal — Wed, 30 Nov 2011 18:44:14 +0100

Conclusion LLIF is a valuable tool for achieving fusion through a minimally invasive approach with little risk to neurovascular structures. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-011-2087-9Authors Matthias Pumberger, Department of Orthopedic Surgery, Spine and Scoliosis Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USAAlexander P. Hughes, Department of Orthopedic Surgery, Spine and Scoliosis Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USARussel R. Huang, Department of Orthopedic Surgery, Spine and Scoliosis Service, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USAAndrew A. Sama, Department of Orthopedic Surgery, Spine and Scoliosis...

How to Measure Scapholunate and Cobb’s Angles on MRI and CT

Journal of Digital Imaging — Wed, 30 Nov 2011 09:21:49 +0100

We present a simple solution to measure angles between structures on different images that can be used both in CT and MR. Content Type Journal ArticlePages 1-4DOI 10.1007/s10278-011-9438-2Authors Zeev V. Maizlin, Department of Radiology, McMaster University Medical Centre, 1200 Main St. West, Hamilton, ON L8N 3Z5, CanadaPatrick M. Vos, Department of Radiology, St.Paul’s Hospital, Vancouver, BC, Canada Journal Journal of Digital ImagingOnline ISSN 1618-727XPrint ISSN 0897-1889 (Source: Journal of Digital Imaging)

Saving Julie from Scoliosis

Medical Headlines From Ivanhoe.com — Wed, 30 Nov 2011 05:00:00 +0100

( Ivanhoe Newswire) -- Look in the mirror ,do you see a slight curve on your back? (Source: Medical Headlines From Ivanhoe.com)

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(i) Clinical assessment of scoliosis

Orthopaedics and Trauma — Mon, 28 Nov 2011 17:14:33 +0100

This article outlines how to perform a thorough history and examination of a patient with scoliosis drawing out the differentiating features of idiopathic scoliosis from other varieties such as congenital, neuromuscular, syndromic and adult scoliosis. (Source: Orthopaedics and Trauma)

(ii) Scoliosis in children and teenagers

Orthopaedics and Trauma — Mon, 28 Nov 2011 17:14:33 +0100

This article discusses the possible causes of scoliosis in the paediatric population. The aim is to provide the reader with a basic understanding of spinal growth, the natural history of scoliotic spinal deformity and outline the options for treatment. (Source: Orthopaedics and Trauma)

(iii) Adult degenerative scoliosis

Orthopaedics and Trauma — Mon, 28 Nov 2011 17:14:33 +0100

Abstract: In an ageing population adult degenerative scoliosis, a subset of adult scoliosis, is a growing problem. The spinal curves, unlike those of idiopathic scoliosis, are predominantly lumbar. Patients usually complain of axial pain, neurogenic claudication and radicular symptoms. Initial conservative management is indicated. If that fails, surgical treatment may be indicated, which requires careful patient selection, pre-operative assessment and pre-optimization to reduce the incidence of complications. Surgery is aimed at correcting the deformity, achieving adequate decompression, while obtaining solid spinal fusion and restoration of adequate coronal and sagittal balance. (Source: Orthopaedics and Trauma)

(iv) Development and treatment of spinal deformity in patients with neurological or myopathic conditions

Orthopaedics and Trauma — Mon, 28 Nov 2011 17:14:33 +0100

Abstract: Children and adolescents with neurological conditions develop severe spinal deformities at a high frequency due to muscle weakness and poor neuromuscular control, frequently associated with spasticity. Scoliosis is the most common type of deformity, occasionally associated with increased kyphosis or lordosis and commonly extending to the sacrum and pelvis. The development of severe spinopelvic imbalance can cause back or costo-pelvic impingement pain, affects the patient’s ability to function, impacts on the patient's quality of life and maximizes the need for nursing care. It may give rise to significant respiratory compromise. Surgical correction is indicated in the presence of a progressive deformity that produces functional limitations and severe symptoms especially in grow...

Diagnostic errors from digital stitching of scoliosis images – the importance of evaluating the source images prior to making a final diagnosis

Pediatric Radiology — Mon, 28 Nov 2011 16:51:00 +0100

Conclusion 16% of digital scoliosis exams had stitching errors that could result in a false diagnosis. The error rate was not influenced by spinal hardware or patient positioning. These results stress the importance of correlating any abnormality on the stitched image with the exam’s source images; if not, a false diagnosis of abnormality will be made. Content Type Journal ArticleCategory Original ArticlePages 1-15DOI 10.1007/s00247-011-2293-yAuthors Nucharin Supakul, Department of Radiology, Indiana University, Riley Hospital for Children, 702 Barnhill Drive, Indianapolis, IN 46202, USAKeith Newbrough, Department of Radiology, Indiana University, Indianapolis, IN, USAMervyn D. Cohen, Department of Radiology, Indiana University, Riley Hospital for Children, 702 Ba...

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MRI: Scoliosis Spinal Fusion Shows Little Disc Degeneration MRI: Scoliosis Spinal Fusion Shows Little Disc Degeneration

Medscape Today Headlines — Mon, 28 Nov 2011 11:50:23 +0100

Can good functional scores and maintenance of correction be realized 10 years post posterior spine fusion in patients with adolescent idiopathic scoliosis? Spine (Source: Medscape Today Headlines)

Conservative treatment of idiopathic scoliosis according to FITS concept: presentation of the method and preliminary, short term radiological and clinical results based on SOSORT and SRS criteria.

Scoliosis — Mon, 28 Nov 2011 05:00:00 +0100

Conclusion: Best results were obtained in 10-25 degrees scoliosis which is a good indication to start therapy before more structural changes within the spine establish. (Source: Scoliosis)

Decreased sleep duration: A risk of progression of degenerative lumbar scoliosis

Medical Hypotheses — Mon, 28 Nov 2011 05:00:00 +0100

Abstract: Degenerative lumbar scoliosis (DLS) is a spinal deformity that develops after skeletal maturity with a Cobb angle of more than 10° in the coronal plane. As the life expectancy of our population increases, DLS becomes a prevalent health issue affecting the quality of life of the elderly. The degree of the scoliosis curvature affects not only the symptoms but also the choice of treatments. Osteoporosis and intervertebral disc degeneration (IDD) have been suggested as two important risks associated with the progression of DLS. Interestingly, recent data implicate interleukin-1 (IL-1) in the altered matrix biology that characterizes human IDD. Compelling evidence links decreased sleep duration to lower bone mineral density (BMD) and elevated expression of IL-1. Based on these eviden...

Bone mineral metabolism in patients with neurofibromatosis type 1 (von Recklingausen disease)

Archives of Dermatological Research — Sat, 26 Nov 2011 16:48:45 +0100

In conclusion, NF1 patients may present a mineral bone involvement, with vitamin D deficiency; calcium and vitamin D supplementation is necessary to restore these bone mineral metabolic alterations. Content Type Journal ArticleCategory Short CommunicationPages 1-7DOI 10.1007/s00403-011-1191-3Authors Luigi Petramala, Department of Internal Medicine and Medical Specialties, Secondary Hypertension Unit, University ‘‘Sapienza’’, Viale del Policlinico 155, 00161 Rome, ItalySandra Giustini, Department of Dermatology, University ‘‘Sapienza’’, Rome, ItalyLaura Zinnamosca, Department of Internal Medicine and Medical Specialties, Secondary Hypertension Unit, University ‘‘Sapienza’’, Viale del Policlinico 155, 00161 Rome, ItalyCristiano Marinelli, Department of Interna...

Biomechanical comparison of alternative densities of pedicle screws for the treatment of adolescent idiopathic scoliosis

European Spine Journal — Sat, 26 Nov 2011 16:48:29 +0100

Conclusions With the same fusion levels, lower density screws allowed achieving similar deformity correction and it was more likely to have lower screw–vertebra loads. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00586-011-2089-7Authors Xiaoyu Wang, Department of Mechanical Engineering, Ecole Polytechnique de Montréal, P.O. Box 6079, Downtown Station, Montreal, QC H3C 3A7, CanadaCarl-Eric Aubin, Department of Mechanical Engineering, Ecole Polytechnique de Montréal, P.O. Box 6079, Downtown Station, Montreal, QC H3C 3A7, CanadaIsabelle Robitaille, Department of Mechanical Engineering, Ecole Polytechnique de Montréal, P.O. Box 6079, Downtown Station, Montreal, QC H3C 3A7, CanadaHubert Labelle, Research Center, Sainte-Justine University...

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A radiographic analysis of degenerative spondylolisthesis at the L4-5 level.

Journal of Neurosurgery.Spine — Fri, 25 Nov 2011 05:00:00 +0100

Conclusions The wide range in all radiographic parameters for LDS confirms the heterogeneous nature of this condition and suggests that a grading system to subclassify LDS may be clinically useful. On flexion and extension radiographs, increased translational motion correlated with increased angular motion. Anterior osteophyte size was not found to be predictive of segmental stability. This data set should prove beneficial to those seeking to subcategorize LDS in the future. PMID: 22117143 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)

Reliability and validity of the AutoCAD software method in lumbar lordosis measurement

Journal of Chiropractic Medicine — Fri, 25 Nov 2011 03:17:44 +0100

Conclusions: AutoCAD showed to be a reliable and valid method to measure lordosis. It is suggested that this method may replace those that are costly and involve health risks, such as radiography, in evaluating lumbar lordosis. (Source: Journal of Chiropractic Medicine)

Sacro-femoral-pubic angle: a coronal parameter to estimate pelvic tilt

European Spine Journal — Thu, 24 Nov 2011 06:49:46 +0100

Conclusion The pelvic tilt is an essential measure in the context of radiographic evaluation of spinal deformity and malalignment. Given the routinely excellent visibility of coronal films this study established the SFP as a coronal parameter which can reliably estimate pelvic tilt. The high correlation and predictive ability of the SFP angle should prompt further study and clinical application when lateral radiographs do not permit assessment of pelvic parameters. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00586-011-2061-6Authors Benjamin Blondel, Spine Division, Hospital for Joint Diseases, New York University, New York, USAFrank Schwab, Spine Division, Hospital for Joint Diseases, New York University, New York, USAAshish Patel, Sp...

Selective thoracolumbar instrumentation with pedicle screws and sublaminar bands (universal clamps) in adolescent idiopathic scoliosis

European Spine Journal — Wed, 23 Nov 2011 17:41:59 +0100

Content Type Journal ArticleCategory Open Operating Theatre (OOT)Pages 1-2DOI 10.1007/s00586-011-2088-8Authors Claudio Lamartina, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, ItalyRiccardo Cecchinato, I.R.C.C.S. Istituto Ortopedico Galeazzi, Milan, Italy Journal European Spine JournalOnline ISSN 1432-0932Print ISSN 0940-6719 (Source: European Spine Journal)

Anatomical distribution of vertebral fractures: comparison of pediatric and adult spines

Osteoporosis International — Wed, 23 Nov 2011 16:40:37 +0100

Conclusions These results suggest that the anatomical distribution of VF differs between children and adults, perhaps relating to the different shape of the immature spine, notably the changing ratio of kyphosis to lordosis. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1837-1Authors K. Siminoski, Department of Radiology and Diagnostic Imaging, University of Alberta, 6628-123 Street, Edmonton, AB, Canada T6H 3T6K.-C. Lee, Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, CanadaH. Jen, Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, CanadaR. Warshawski, Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, CanadaM. A. Matzinger, Department...

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Poland Syndrome Associated With Ipsilateral Lipoma and Dextrocardia [CASE REPORTS]

The Annals of Thoracic Surgery — Wed, 23 Nov 2011 05:00:00 +0100

A 22-year-old man was admitted with a rapidly enlarging soft mass on the left chest wall, which was diagnosed as lipoma by postoperative pathology. A chest roentgenogram revealed a defect of the fourth rib, scoliosis, dextrocardia, and diaphragmatic hernia. A computed tomographic scan showed maldevelopment of the pectoralis major and minor muscles. This is the first reported case of Poland syndrome with ipsilateral lipoma of the chest wall. Dextrocardia associated with Poland syndrome may be considered dextroposition, rather than a dextroinversion, and it may arise as a result of Poland syndrome. (Source: The Annals of Thoracic Surgery)

Bilateral spondylolysis of inferior articular processes of the fourth lumbar vertebra: a case report.

Upsala Journal of Medical Sciences — Wed, 23 Nov 2011 05:00:00 +0100

We report a rare case of bilateral spondylolysis of inferior articular processes of L4 vertebra that caused spinal canal stenosis with a significant segmental instability at L4/5 and scoliosis. A 31-year-old male who had suffered from low back pain since he was a teenager presented with numbness of the right lower leg and scoliosis. Plain X-rays revealed bilateral spondylolysis of inferior articular processes of L4, anterolisthesis of the L4 vertebral body, and right lateral wedging of the L4/5 disc with compensatory scoliosis in the cephalad portion of the spine. MR images revealed spinal canal stenosis at the L4/5 disc level. Posterior lumbar interbody fusion of the L4/5 was performed, and his symptoms were relieved. PMID: 22111522 [PubMed - as supplied by publisher] (Source: Upsala ...

Use of zoledronic acid in the treatment of osteoporosis in a teenager with osteogenesis imperfecta

Bone — Tue, 22 Nov 2011 16:58:00 +0100

Bisphosphonates are useful drugs for the treatment of osteoporosis. They inhibit osteoclastic activity (antiresorptives). Administration of pamidronate in intravenous cycles is the usual treatment of osteoporosis in patients with osteogenesis imperfecta (OI). Recent reports propose the use of zoledronic acid (ZA) as a therapeutic option in these patients. This presentation shows the efficacy of ZA in a teenage boy with OI without previous treatment of his low bone mass. The patient was first seen at age 12years and 6months; he used a thoraco-lumbar corset. He had been diagnosed OI and had previous history of two fractures (one in the right femur, another in the left ankle). His lumbar BMD had a Z-score of −4.7 (L2–L4: 0.274g/cm², Hologic). He met the pediatric criteria of secondary os...

Osteogenesis imperfecta (OI) and bone tumor which mimic malignant neoplasm

Bone — Tue, 22 Nov 2011 16:58:00 +0100

OI type V is characterized by fragile bones and also calcification of interosseous membrane between radius and ulna, dense radiolucent band adjacent to growth cartilage and hypertrophic calluses in fracture sites. We refer a 27-year-old patient with OI type V who presented multiple fractures during childhood and adolescence which got better with bisphosphonates, calcium and vitamin D treatment. A tumor could be observed in his left elbow, which disappeared during the adolescent period. The patient uses a wheel chair, has short stature 1.40m, multiple deformations and white sclerotics. A 10-cm diameter tumor was found in sole region of the left foot. The bone and mineral metabolism was normal. A low bone mass was seen at the total body BMD (Z: –2.3). The X-ray showed bilateral cubito-radi...

A comparative study of axis-line-distance technique and Cobb method on assessing the curative effect on scoliosis

European Spine Journal — Mon, 21 Nov 2011 17:53:57 +0100

Conclusion The ALDT is better than the Cobb method for therapeutic evaluation of scoliosis during treatment and at follow-up visits. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00586-011-2081-2Authors Jia-Wei He, Radiology Department, The 2nd Affiliated Hospital of Wenzhou Medical College, #109 Xue Yuan Xi Lu, Wenzhou, ChinaGuang-Hui Bai, Radiology Department, The 2nd Affiliated Hospital of Wenzhou Medical College, #109 Xue Yuan Xi Lu, Wenzhou, ChinaXin-Jian Ye, Radiology Department, The 2nd Affiliated Hospital of Wenzhou Medical College, #109 Xue Yuan Xi Lu, Wenzhou, ChinaKun Liu, Radiology Department, The 2nd Affiliated Hospital of Wenzhou Medical College, #109 Xue Yuan Xi Lu, Wenzhou, ChinaZhi-Han Yan, Radiology Department, The 2nd Affi...

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Untreated Scheuermann’s disease: a 37-year follow-up study

European Spine Journal — Mon, 21 Nov 2011 06:32:37 +0100

Conclusion Scheuermann’s patients had a higher risk for back pain and disabilities during activities of daily living than controls. However, the degree of thoracic kyphosis among Scheuermann’s patients was not related to back pain, quality of life, or general health. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00586-011-2075-0Authors L. Ristolainen, ORTON Orthopaedic Hospital and ORTON Research Institute, Helsinki, FinlandJ. A. Kettunen, Arcada, The University of Applied Sciences, Helsinki, FinlandM. Heliövaara, National Institute for Health and Welfare, Helsinki, FinlandU. M. Kujala, Department of Health Sciences, University of Jyväskylä, Jyväskylä, FinlandA. Heinonen, Department of Health Sciences, University of Jyväskylä, ...

Physical capacity of girls with mild and moderate idiopathic scoliosis: influence of the size, length and number of curvatures

European Spine Journal — Mon, 21 Nov 2011 06:32:37 +0100

Conclusion The maximum oxygen intake and the output during the PWC170 test is lower in girls with moderate scoliosis than in the control group. The value of maximum oxygen intake and output obtained during the PWC170 test in girls with mild scoliosis does not differ significantly from the values obtained in the control group. The number of vertebrae involved in scoliotic deformation and the number of curvatures cause significant decrease in only the relative value of the output obtained during an exercise test. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00586-011-2068-zAuthors Dariusz Czaprowski, Faculty of Physiotherapy, Józef Rusiecki University College in Olsztyn, Bydgoska 33, 10-243 Olsztyn, PolandTomasz Kotwicki, Department of...

Anesthetic management of vaginal delivery in a parturient with hemochromatosis induced end-organ failure

International Journal of Obstetric Anesthesia — Mon, 21 Nov 2011 05:00:00 +0100

Abstract: The vast majority of females affected by hemochromatosis are asymptomatic during childbearing years. We were able to provide effective obstetric anesthesia care to a 35-year-old woman with severe hemochromatosis. She had systolic heart failure with a left ventricular ejection fraction of 15%, severe pulmonary hypertension, mitral insufficiency, a history of ventricular tachycardia, cirrhosis, obstructive sleep apnea, gestational diabetes, and severe scoliosis. A multidisciplinary approach was used to stabilize her heart failure and prepare her for childbirth. An arterial line and epidural analgesic were placed before induction of labor. Vaginal delivery was accomplished with passive decent of the fetus and forceps assistance. We discuss hemochromatosis and its implications for th...

Kyphectomy for congenital kyphosis due to meningomyelocele: a case treated with a modified approach to skin healing

International Wound Journal — Sat, 19 Nov 2011 23:25:24 +0100

This study is a case report of a meningomyelocele patient with congenital kyphosis who was treated with kyphectomy and a special approach to soft tissue healing. The objective of this study is to show a step by step approach to surgical treatment and postoperative care of a meningomyelocele patient with congenital kyphosis. In meningomyelocele the incidence of kyphosis is around 12–20%. It may cause recurrent skin ulcerations, impaired sitting balance and respiratory compromise. Kyphectomy has first been described by Sharrard. This surgery is prone to complications including pseudoarthrosis, skin healing problems, recurrence of deformity and deep infections. A 15‐year‐old male presented with congenital kyphosis due to meningomyelocele. He had back pain, deformity and bedsores at the ...

Heritability of scoliosis

European Spine Journal — Fri, 18 Nov 2011 06:58:29 +0100

Conclusion Using self-reported data on scoliosis from the Swedish Twin Registry, we estimate that 38% of the variance in the liability to develop scoliosis is due to additive genetic effects and 62% to unique environmental effects. This is the first study of sufficient size to make heritability estimates of scoliosis. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00586-011-2074-1Authors Anna Grauers, Department of Orthopaedics, Karolinska University Hospital, Stockholm, SwedenIffat Rahman, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, SwedenPaul Gerdhem, Department of Orthopaedics, Karolinska University Hospital, Stockholm, Sweden Journal European Spine JournalOnline ISSN 1432-0932Print IS...

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Geometrical values of the normal and arthritic hip and knee detected with the EOS imaging system

International Orthopaedics — Fri, 18 Nov 2011 06:57:52 +0100

Conclusion EOS 2D/3D with its sterEOS 3D reconstruction is useful for a comprehensive 3D examination of the lower limb. In the near future it may be suitable for daily routine diagnostics of orthopedic lower limb deformities as a primary examination method. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00264-011-1403-7Authors Peter Than, Department of Orthopedic Surgery, Institute of Musculoskeletal Surgery, University of Pécs, Pécs, HungaryKinga Szuper, Department of Orthopedic Surgery, Institute of Musculoskeletal Surgery, University of Pécs, Pécs, HungarySzabolcs Somoskeöy, Department of Orthopedic Surgery, Institute of Musculoskeletal Surgery, University of Pécs, Pécs, HungaryVilmos Warta, Department of Languages for Specific Pur...

Effect of two sitting postures on lumbar sagittal alignment and intervertebral discs in runners

La Radiologia Medica — Fri, 18 Nov 2011 06:53:18 +0100

Conclusions Intervertebral discs undergo significant strain after 1 h of running that in the long term may lead patoto low back pain and degenerative disc disease. Runners, especially those with low back pain and degenerative disc disease, should be evaluated after training to preserve the normal lumbar lordosis. Content Type Journal ArticleCategory Musculoskeletal Radiology / Radiologia Muscolo-ScheletricaPages 1-15DOI 10.1007/s11547-011-0748-8Authors A. Dimitriadis, Department of Orthopaedics, University of Crete, Crete, GreeceF. Smith, Department of Radiology, University of Aberdeen, Scotland, UKA. F. Mavrogenis, Dipartimento di Ortopedia, Istituto Ortopedico Rizzoli, Via Pupilli 1, 40136 Bologna, ItalyM. H. Pope, Department of Radiology, University of Aberdeen, S...

Mutations in the Notch Pathway Alter the Patterning of Multifidus

The Anatomical Record Part B: The New Anatomist — Fri, 18 Nov 2011 05:00:00 +0100

AbstractClinical studies have suggested that defects in the epaxial muscles, particularly multifidus, may contribute to the etiology of idiopathic scoliosis. While the epaxial muscles and the vertebrae derive from the same embryonic segmentation process, the mechanisms that pattern the multisegmental back muscles are still unclear. The process of segmentation is regulated by the Notch signaling pathway, and mutations in the modulators delta‐like 3 (Dll3) and lunatic fringe (Lfng) are genetic models for spinal disorders such as scoliosis. Osteological defects have been characterized in these genetic models, but myological phenotypes have not previously been studied. We analyzed the multifidus muscle in the mouse (Mus musculus) and observed intriguing changes in the cranio‐caudal borders...

Recurrent pneumonia due to esophageal migration of the gastrostomy MIC-Key tube remnant causing proximal esophageal obstruction

Respiratory Medicine CME — Thu, 17 Nov 2011 12:48:12 +0100

Abstract: A 16 years old female with history of cerebral palsy, juvenile rheumatoid arthritis and severe scoliosis presents for recurrent pneumonia. Multiple prior plain films demonstrate progressive increased consolidation confined to the left lower lobe. Subsequently, a CT of the chest was preformed which showed a plastic gastrostomy (MIC-Key tube) bumper in the proximal esophagus causing severe tracheal narrowing. The patient underwent endoscopic removal of the gastrostomy bumper without incident. (Source: Respiratory Medicine CME)

Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis type 1

Journal of Orthopaedic Research — Thu, 17 Nov 2011 07:41:30 +0100

AbstractIndividuals with nerofibromatosis Type 1 (NF1) frequently suffer a spectrum of bone pathologies, such as abnormal skeletal development (scoliosis, congenital bowing, and congenital pseudoarthroses, etc), lower bone mineral density with increased fracture risk. These skeletal problems may result, in part, from abnormal osteoclastogenesis. Enhanced RAS/PI3K activity has been reported to contribute to abnormal osteoclastogenesis in Nf1 heterozygous (Nf1+/−) mice. However, the specific downstream pathways linked to NF1 abnormal osteoclastogenesis have not been defined. Our aim was to determine whether mammalian target of rapamycin (mTOR) was a key effector responsible for abnormal osteoclastogenesis in NF1. Primary osteoclast‐like cells (OCLs) were cultured from Nf1 wild‐type (Nf...

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Syrinx resolution after posterior fossa decompression in patients with scoliosis secondary to Chiari malformation type I

European Spine Journal — Wed, 16 Nov 2011 06:49:14 +0100

Conclusion Syringes showed significant improvement after PFD in most patients with scoliosis secondary to CMI. Resolution generally occurred within 6 months follow-up and continued at a slow rate for several years. In addition, the severity of tonsillar descent is a potential predictor for better improvement after standard PFD. Content Type Journal ArticleCategory Chinese sectionPages 1-8DOI 10.1007/s00586-011-2064-3Authors Tao Wu, Department of Spine Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Zhongshan Road No. 321, Nanjing, 210008 ChinaZezhang Zhu, Department of Spine Surgery, Affiliated Drum Tower Hospital of Nanjing University Medical School, Zhongshan Road No. 321, Nanjing, 210008 ChinaJian Jiang, Department of Neurosurg...

Combined Anterior-Posterior Surgery is the Most Important Risk Factor for Developing Proximal Junctional Kyphosis in Idiopathic Scoliosis.

Clinical Orthopaedics and Related Research — Wed, 16 Nov 2011 05:00:00 +0100

CONCLUSIONS: Patients with a T1 through T3 upper instrumented level, combined anterior-posterior surgery, and increased sagittal sacral vertical line difference had a higher likelihood of developing PJK. Of these risk factors, anterior-posterior surgery was the strongest risk factor. LEVEL OF EVIDENCE: Level III, prognostic study. See Guidelines for Authors for a complete description of levels of evidence. PMID: 22086507 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)

A Study of Postural Changes After Breast Augmentation

Aesthetic Plastic Surgery — Tue, 15 Nov 2011 06:48:29 +0100

Conclusion We believe that with respect to posture, the role played by psychological aspects is even more important than that played by changes in body mass. Indeed, hypomastia is often associated with kyphosis because patients try to hide what they consider a deficiency. Following breast augmentation, the discovery of new breasts overcomes the dissatisfaction with the patient’s own body image, increases self-esteem, and modifies posture regardless of the changes in body mass due to the insertion of the implants. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00266-011-9841-6Authors Marco Mazzocchi, Department of Plastic Surgery, University of Perugia, Perugia, ItalyLuca Andrea Dessy, Department of Plastic Surgery, “La Sapienza” U...

Iliac crest orientation and geometry in able-bodied and non-treated adolescent idiopathic scoliosis girls with moderate and severe spinal deformity

European Spine Journal — Tue, 15 Nov 2011 06:48:13 +0100

Conclusions Differences in iliac spine geometries occurred in the transverse plane correlating to Cobb angles which suggest altered bone growth in AIS girls. Such findings could indicate right thoracic spinal deformity as a result of pelvic torsion. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-011-2070-5Authors Georgios A. Stylianides, Department of Exercise Science and Sport, John Long Center, University of Scranton, 800 Linden Street, Scranton, PA 18510, USAMarléne Beaulieu, Department of Kinesiology, University of Montreal, Montreal, QC, CanadaGeorges Dalleau, CURAPS-DIMPS, Faculté des Sciences de l’Homme et de l’Environnement, Université de la Réunion, Le Tampon, FranceCharles-Hilaire Rivard, Human Movement Laboratory, ...

Postnatal growth defect in mice upon persistent Hoxa2 expression in the chondrogenic cell lineage.

Differentiation — Tue, 15 Nov 2011 05:00:00 +0100

In conclusion, the sustained expression of Hoxa2 in the chondrocyte lineage is characterized by a proportionate short stature resulting from skeletal growth defect. The indepth analysis of cartilage and bone histogenesis points towards an initial deficit in cell mobilization to enter chondrogenesis. PMID: 22093256 [PubMed - as supplied by publisher] (Source: Differentiation)

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Expert’s comment concerning Grand Rounds case entitled “Congenital kypho-scoliosis: a case of Thoracic Insufficiency Syndrome and the limitations of treatment” (by A.D. Chatterjee, K. Hassan and M.P. Grevitt)

European Spine Journal — Mon, 14 Nov 2011 16:54:26 +0100

Content Type Journal ArticleCategory Grand RoundsPages 1-3DOI 10.1007/s00586-011-2066-1Authors Francisco J. Sanchez Perez-Grueso, Chair of Spine Surgery Unit, Hospital La Paz, Pº de la Castellana 261, 28046 Madrid, Spain Journal European Spine JournalOnline ISSN 1432-0932Print ISSN 0940-6719 (Source: European Spine Journal)

Complex Spinal-Paraspinal Fast-Flow Lesions in CLOVES Syndrome: Analysis of Clinical and Imaging Findings in 6 Patients [PEDIATRICS]

American Journal of Neuroradiology — Mon, 14 Nov 2011 05:00:00 +0100

We report the occurrence of spinal-paraspinal fast-flow lesions within or adjacent to the truncal overgrowth or a cutaneous birthmark in 6 patients with CLOVES syndrome. (Source: American Journal of Neuroradiology)

Major role of suckling stimulation for inhibition of estrous behaviors in lactating rabbits: Acute and chronic effects.

Hormones and Behavior — Sun, 13 Nov 2011 05:00:00 +0100

Authors: García-Dalmán C, González-Mariscal G Abstract Lactation in rabbits induces anestrus: sexual receptivity and scent-marking (chinning) are reduced despite the brevity of suckling (one daily nursing bout, lasting around 3min). The mechanisms underlying this effect are unknown but, as chinning, lordosis, and ambulation in an open field are immediately inhibited by the peripheral stimulation received during mating we hypothesized that, across lactation, suckling stimulation would provoke a similar effect. To test this possibility we provided litters of 1, 3, 5, or 10 pups across lactation days 1-15 and quantified chinning and ambulation frequencies, the lordosis quotient, and milk output. Baseline chinning frequency, determined before the daily nursing bout, was low across l...

Learning curve of thoracic pedicle screw placement using the free-hand technique in scoliosis: how many screws needed for an apprentice?

European Spine Journal — Fri, 11 Nov 2011 12:48:20 +0100

Conclusions For an apprentice, an experience of at least 60 screw placements under the direction of an experienced surgeon is needed for inserting the TPS in scoliosis using the free-hand technique independently. Content Type Journal ArticleCategory Chinese sectionPages 1-6DOI 10.1007/s00586-011-2065-2Authors Chen Gang, Department of Orthopedic Surgery, The 2nd Affiliated Hospital of Medical College of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009 Zhejiang, ChinaLi Haibo, Department of Orthopedic Surgery, The 2nd Affiliated Hospital of Medical College of Zhejiang University, 88 Jiefang Road, Hangzhou, 310009 Zhejiang, ChinaLi Fancai, Department of Orthopedic Surgery, The 2nd Affiliated Hospital of Medical College of Zhejiang University, 88 Jiefang Road, Hang...

Laminectomy, durotomy, and piotomy effects on spinal cord intramedullary pressure in severe cervical and thoracic kyphotic deformity: a cadaveric study.

Journal of Neurosurgery.Spine — Fri, 11 Nov 2011 05:00:00 +0100

Conclusions In this cadaveric study, laminar decompression reduced ?IMP by approximately 15%?25%, while correction of the kyphotic deformity returned ?IMP to zero. This study helps explain the pathophysiology of myelopathy in kyphotic deformity and the failure of laminectomy alone for cervical and thoracic kyphotic deformities with myelopathy. In addition, the study emphasizes the need for correction of deformity during operative treatment of kyphotic deformity, the need for maintaining adequate intraoperative blood pressure during operative treatment, and the higher risk of spinal cord injury associated with operative treatment of kyphotic deformity. PMID: 22077470 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)

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Single-stage posterior instrumentation and anterior debridement for active tuberculosis of the thoracic and lumbar spine with kyphotic deformity

International Orthopaedics — Tue, 08 Nov 2011 19:14:29 +0100

Conclusion Single-stage posterior instrumentation and anterior debridement with fusion was demonstrated to be a safe and effective method to achieve spinal decompression and kyphosis correction in patients with Pott’s disease. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00264-011-1389-1Authors Xiao-bin Wang, Department of Spine Surgery, The Second Xiangya Hospital of Central South University, 139# Middle of Renmin Road, Changsha, Hunan 410011, People’s Republic of ChinaJing Li, Department of Spine Surgery, The Second Xiangya Hospital of Central South University, 139# Middle of Renmin Road, Changsha, Hunan 410011, People’s Republic of ChinaGuo-hua Lü, Department of Spine Surgery, The Second Xiangya Hospital of Central South Universi...

Two-stage posterior-only procedures for correction of severe spinal deformities

Archives of Orthopaedic and Trauma Surgery — Tue, 08 Nov 2011 16:50:58 +0100

Conclusions The two-stage posterior-only procedures permitting stepwise correction for the treatment of severe spinal deformities provide safe and satisfactory outcomes in this patient population. Content Type Journal ArticleCategory Orthopaedic SurgeryPages 1-9DOI 10.1007/s00402-011-1415-1Authors Xiaofei Cheng, Department of Orthopedics, CPLA 306 Hospital, 9 North Anxiang Road, Beijing, 100101 ChinaHuasong Ma, Department of Orthopedics, CPLA 306 Hospital, 9 North Anxiang Road, Beijing, 100101 ChinaRong Tan, Department of Orthopedics, CPLA 306 Hospital, 9 North Anxiang Road, Beijing, 100101 ChinaJigong Wu, Department of Orthopedics, CPLA 306 Hospital, 9 North Anxiang Road, Beijing, 100101 ChinaJianwei Zhou, Department of Orthopedics, CPLA 306 Hospital, 9 North Anxian...

Use of the iPhone for Cobb angle measurement in scoliosis

European Spine Journal — Tue, 08 Nov 2011 06:50:02 +0100

Conclusions We conclude that the iPhone is an equivalent Cobb measurement tool to the manual protractor, and measurement times are about 15% less. The widespread availability of inclinometer-equipped mobile phones and the ability to store measurements in later versions of the angle measurement software may make these new technologies attractive for clinical measurement applications. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00586-011-2059-0Authors Matthew Shaw, Paediatric Spine Research Group, Queensland University of Technology and Mater Health Services, Brisbane, AustraliaClayton J. Adam, Paediatric Spine Research Group, Queensland University of Technology and Mater Health Services, Brisbane, AustraliaMaree T. Izatt, Paediatric Spi...

Pedicle subtraction osteotomy through pseudarthrosis to correct thoracolumbar kyphotic deformity in advanced ankylosing spondylitis

European Spine Journal — Tue, 08 Nov 2011 06:50:00 +0100

Conclusion PSO can be safely performed through the site of pseudarthrotic lesion in AS patients with pseudarthrosis and kyphotic deformity. After PSO, supplemental anterior fusion is sometimes necessary to support the anterior and middle column in a second stage if there is a bone defect in the osteotomy site. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-011-2054-5Authors Bang-ping Qian, Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 321, Zhongshan Road, 210008 Nanjing, ChinaYong Qiu, Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, 321, Zhongshan Road, 210008 Nanjing, ChinaBin Wang, Spine Surgery, The Affiliated Drum Tower Hospital of Nanjing Universi...

Efficacy of exercise therapy for the treatment of adolescent idiopathic scoliosis: a review of the literature

European Spine Journal — Mon, 07 Nov 2011 16:59:50 +0100

Conclusions This unbiased literature review has revealed poor quality evidence supporting the use of exercise therapy in the treatment of AIS. Well-designed randomised controlled studies are required to assess the role of exercise therapy in AIS. Content Type Journal ArticleCategory Review ArticlePages 1-8DOI 10.1007/s00586-011-2063-4Authors Simon C. Mordecai, Department of Trauma and Orthopaedics, Salisbury NHS Foundation Trust, Salisbury District Hospital, Salisbury, Wiltshire SP2 8BJ, UKHarshad V. Dabke, Department of Trauma and Orthopaedics, Salisbury NHS Foundation Trust, Salisbury District Hospital, Salisbury, Wiltshire SP2 8BJ, UK Journal European Spine JournalOnline ISSN 1432-0932Print ISSN 0940-6719 (Source: European Spine Journal)

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Nonoperative versus Operative Treatment for Thoracolumbar Burst Fractures Without Neurologic Deficit: A Meta-analysis.

Clinical Orthopaedics and Related Research — Sat, 05 Nov 2011 04:00:00 +0100

CONCLUSIONS: Operative management of thoracolumbar burst fractures without neurologic deficit may improve residual kyphosis, but does not appear to improve pain or function at an average of 4 years after injury and is associated with higher complication rates and costs. LEVEL OF EVIDENCE: Level II, therapeutic study. See the Guidelines for Authors for a complete description of level of evidence. PMID: 22057820 [PubMed - as supplied by publisher] (Source: Clinical Orthopaedics and Related Research)

Lowest instrumented vertebra selection in Lenke 3C and 6C scoliosis: what if we choose lumbar apical vertebra as distal fusion end?

European Spine Journal — Fri, 04 Nov 2011 16:50:37 +0100

Conclusion In conclusion, in Lenke 3C and 6C scoliosis, post-op lumbar curve behaviour differs due to different choices of LIV with reference to LAV, that is, the deviation of lumbar curve improves when the LIV is either at or below the LAV but deteriorates when the LIV is above the LAV. Although the greatest correction occurs when the LIV is below the LAV, choosing LAV as LIV can still be the optimal option in certain cases, since it can yield similar correction while preserving more lumbar mobility and growth potential. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00586-011-2058-1Authors Yu Wang, Department of Orthopaedics E, Aarhus University Hospital, Norrebrogade 44, 8000 Aarhus, DenmarkCody Eric Bünger, Department of Orthopaed...

Comparison of one-stage anteroposterior and posterior-alone hemivertebrae resection combined with posterior correction for hemivertebrae deformity: Results of 60 patients

Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1) — Fri, 04 Nov 2011 04:00:00 +0100

Conclusion: Posterior hemivertebrael resection is a promising approach for congenital scoliosis in terms of relative safety, degree of correction achieved, reduced operative time and blood loss. (Source: Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1))

Outcome of single level instrumented posterior lumbar interbody fusion using corticocancellous laminectomy bone chips

Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1) — Fri, 04 Nov 2011 04:00:00 +0100

Conclusion: Corticocancellous laminectomy bone chips alone can be used as a means of spinal fusion in patients with single level instrumented PLIF. This has got a good fusion rate. (Source: Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1))

Comparison of one-stage anteroposterior and posterior-alone hemivertebrae resection combined with posterior correction for hemivertebrae deformity

Table of Contents : Indian Journal of Orthopaedics : 2007 - 41(1) — Fri, 04 Nov 2011 04:00:00 +0100

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Congenital kypho-scoliosis: a case of thoracic insufficiency syndrome and the limitations of treatment

European Spine Journal — Wed, 02 Nov 2011 16:58:33 +0100

Conclusions This article highlights the features of congenital kypho-scoliosis and TIS. The difficulties of treating kyphosis when combined with TIS are discussed together with the limitations of current surgical techniques. Content Type Journal ArticleCategory Grand RoundsPages 1-7DOI 10.1007/s00586-011-2032-yAuthors A. D. Chatterjee, Centre for Spinal Studies and Surgery, D Floor, West Block, Queens Medical Centre, Derby Road, Nottingham, NG7 2UH, UKK. Hassan, Centre for Spinal Studies and Surgery, D Floor, West Block, Queens Medical Centre, Derby Road, Nottingham, NG7 2UH, UKM. P. Grevitt, Centre for Spinal Studies and Surgery, D Floor, West Block, Queens Medical Centre, Derby Road, Nottingham, NG7 2UH, UK Journal European Spine JournalOnline ISSN 1432-0932...

Patients with adolescent idiopathic scoliosis of Lenke type-1 curve exhibit specific pedicle width pattern

European Spine Journal — Tue, 01 Nov 2011 16:52:02 +0100

Conclusions Our study showed that patients with Lenke type 1 curve exhibit smaller pedicles and asymmetric pedicle width compared with control subjects. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00586-011-2055-4Authors Kasim Abul-Kasim, Faculty of Medicine, Division of Neuroradiology, Diagnostic Centre for Imaging and Functional Medicine, Skåne University Hospital, Lund University, 205 02 Malmö, SwedenAcke Ohlin, Department of Orthopaedic Surgery, Faculty of Medicine, Skåne University Hospital, Lund University, 205 02 Malmö, Sweden Journal European Spine JournalOnline ISSN 1432-0932Print ISSN 0940-6719 (Source: European Spine Journal)

The impact of halo-gravity traction on curve rigidity and pulmonary function in the treatment of severe and rigid scoliosis and kyphoscoliosis: a clinical study and narrative review of the literature

European Spine Journal — Tue, 01 Nov 2011 05:54:36 +0100

Conclusion The improvement of pulmonary function and the restoration of sagittal and coronal balance are the main goals in the treatment of severe and rigid scoliosis and kyphoscoliosis. A review of the literature showed that HGT is a useful tool for selected patients. Preoperative HGT is indicated in severe curves with moderate to severe pulmonary compromise. HGT should not be expected to significantly improve severe curves without a prior anterior and/or posterior release. The data presented in this study can be used in future studies to compare the surgical and pulmonary outcomes of severe and rigid deformities. Content Type Journal ArticleCategory Original ArticlePages 1-16DOI 10.1007/s00586-011-2046-5Authors Heiko Koller, German Scoliosis Center Bad Wildungen...

Lumbar lordosis of extinct hominins

American Journal of Physical Anthropology — Tue, 01 Nov 2011 04:00:00 +0100

AbstractThe lordotic curvature of the lumbar spine (lumbar lordosis) in humans is a critical component in the ability to achieve upright posture and bipedal gait. Only general estimates of the lordotic angle (LA) of extinct hominins are currently available, most of which are based on the wedging of the vertebral bodies. Recently, a new method for calculating the LA in skeletal material has become available. This method is based on the relationship between the lordotic curvature and the orientation of the inferior articular processes relative to vertebral bodies in the lumbar spines of living primates. Using this relationship, we developed new regression models in order to calculate the LAs in hominins. The new models are based on primate group‐means and were used to calculate the LAs in ...

Lumbar Lordosis Restoration Following Single-level Instrumented Fusion Comparing 4 Commonly Used Techniques.

Orthopedics — Tue, 01 Nov 2011 04:00:00 +0100

Authors: Dimar JR, Glassman SD, Vemuri VM, Esterberg JL, Howard JM, Carreon LY Abstract A major sequelae of lumbar fusion is acceleration of adjacent-level degeneration due to decreased lumbar lordosis. We evaluated the effectiveness of 4 common fusion techniques in restoring lordosis: instrumented posterolateral fusion, translumbar interbody fusion, anteroposterior fusion with posterior instrumentation, and anterior interbody fusion with lordotic threaded (LT) cages (Medtronic Sofamor Danek, Memphis, Tennessee). Radiographs were measured preoperatively, immediately postoperatively, and a minimum of 6 months postoperatively. Parameters measured included anterior and posterior disk space height, lumbar lordosis from L3 to S1, and surgical level lordosis.No significant difference in ...

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Postural Assessment of Lumbar Lordosis and Pelvic Alignment Angles in Adolescent Users and Nonusers of High-Heeled Shoes

Journal of Manipulative and Physiological Therapeutics — Tue, 01 Nov 2011 04:00:00 +0100

Conclusion: For the subjects in this study, the use of high-heeled shoes is correlated with increased lumbar lordosis and pelvic anteversions. Lumbar lordosis angles are correlated with age for the NUG when barefoot. (Source: Journal of Manipulative and Physiological Therapeutics)

Sagittal spinopelvic alignment and body mass index in patients with degenerative spondylolisthesis. Schuller S, Charles YP, Steib JP. Eur Spine J 2011;20(5):713–9. Epub 2010 Dec 1.

The Spine Journal — Tue, 01 Nov 2011 04:00:00 +0100

The sagittal orientation and osteoarthritis of facet joints, paravertebral muscular dystrophy and loss of ligament strength represent mechanical factors leading to degenerative spondylolisthesis. The importance of sagittal spinopelvic imbalance has been described for the developmental spondylolisthesis with isthmic lysis. However, it remains unclear if these mechanisms play a role in the pathogenesis of degenerative spondylolisthesis. The purpose of this study was to analyze the sagittal spinopelvic alignment, the body mass index (BMI) and facet joint degeneration in degenerative spondylolisthesis. A group of 49 patients with L4-L5 degenerative spondylolisthesis (12 males, 37 females, average age 65.9 years) was compared to a reference group of 77 patients with low back pain without spondy...

Outcomes of anterior and posterior instrumentation under different surgical procedures for treating thoracic and lumbar spinal tuberculosis in adults

International Orthopaedics — Mon, 31 Oct 2011 17:02:27 +0100

Conclusion These results suggest that both anterior and posterior instrumentation attain good results for correction of the deformity and maintaining correction, foci clearance, spinal-cord decompression and pain relief in the treatment of thoracic and lumbar spinal TB providing that the opeartive indication is accurately identified. However, the posterior approach may be superior to anterior instrumentation to correct deformity and maintain that correction. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00264-011-1390-8Authors Yuan Zheng Ma, Department of Orthopaedics, The 309th hospital of PLA, Beijing, ChinaXu Cui, Department of Orthopaedics, The 309th hospital of PLA, Beijing, ChinaHong Wei Li, Department of Orthopaedics, The 309th hos...

Is decreased bone mineral density associated with development of scoliosis? A bipedal osteopenic rat model

Scoliosis — Mon, 31 Oct 2011 04:00:00 +0100

Conclusions: This study has revealed two important findings. One is that bipedality (in the absence of pinealectomy) by itself may be a cause of scoliosis in this animal model. Further studies on animal models need to consider bipedality as an independent factor. Secondly, relative hypokyphosis in osteopenic animals may have important implications. The absence of sagittal plane analyses in previous studies makes comparison impossible, but nonetheless these findings suggest that osteopenia may be important in the development of 3D deformity in adolescent idiopathic scoliosis. (Source: Scoliosis)

Problems and complications in VEPTR-based treatment.

Ortopedia, Traumatologia, Rehabilitacja — Mon, 31 Oct 2011 04:00:00 +0100

Authors: Latalski M, Fatyga M, Gregosiewicz A Abstract Aim of the study. Early-onset scoliosis with co-existing thoracic deformity is particularly difficult to treat, with early surgery usually being the only rational solution. Operative correction of the deformed spine and rib cage employs techniques enabling further growth of the structures, an example of which is the Vertical Expandable Prosthetic Titanium Rib (VEPTR), designed to provide dynamic stabilization of the spinal column and the thoracic cage. Our study aimed to present difficulties and complications related to VEPTR-based operative reduction of the spinal and thoracic deformities in the youngest child. Material and methods. Twelve children aged 3 to 9 years (a mean age of 5.25 years) underwent sequential VEPTR-based s...

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Does hormone replacement therapy prevent lateral rotatory spondylolisthesis in postmenopausal women?

European Spine Journal — Fri, 28 Oct 2011 06:06:18 +0100

Conclusions LRO was significantly lower in women who received HRT. The excess risk of LRO was dependent on both age and HRT status. These findings suggest that HRT might prevent the onset of LRO, and therefore might contribute to the prevention of low back pain. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00586-011-2048-3Authors Catherine Marty-Poumarat, Groupe Rachis Garches, Hôpital R. Poincaré, APHP, 92380 Garches, FranceAgnès Ostertag, Hôpital Lariboisière, INSERM U606 and University Paris-Diderot Paris 7, 2 rue Ambroise Paré, 75010 Paris, FranceClaude Baudoin, Hôpital Lariboisière, INSERM U606 and University Paris-Diderot Paris 7, 2 rue Ambroise Paré, 75010 Paris, FranceMichèle Marpeau, Groupe Rachis Garches, Hôpital R. ...

Spinal infections in children: a review

International Orthopaedics — Fri, 28 Oct 2011 06:04:57 +0100

Abstract Spondylodiscitis affects children aged between two and eight years, and mainly involves the lumbar or lumbosacral spine. Diagnosis is difficult because the symptoms are not very specific and due to the children’s difficulty in communicating. Unlike adults, children have vascularised intervertebral discs, which explains the higher incidence of this disease in this age group. C-reactive protein, and blood and urine cultures are important laboratory tests. In most cases, fine needle or traditional biopsy helps identify the pathogen particularly in patients who do not respond to the antibiotic therapy test. Magnetic resonance imaging has high sensitivity and specificity in the investigation of pyogenic infection of the spine, particularly in the early stages, when t...

Long-term follow-up of cervical radiographic sagittal spinal alignment after 1- and 2-level cervical corpectomy for the treatment of spondylosis of the subaxial cervical spine causing radiculomyelopathy or myelopathy: a retrospective study.

Journal of Neurosurgery.Spine — Fri, 28 Oct 2011 04:00:00 +0100

Conclusions Long-term follow-up data in our veteran population support cervical corpectomy as an effective, long-lasting treatment for spondylotic myelopathy of the cervical spine. Use of CTMCs without end caps was associated with statistically significant increased postoperative kyphotic angulation and chronic pain. Despite an increase in focal kyphosis over time, regional cervical sagittal lordotic alignment had increased at the latest follow-up. Further investigation will include the association of chronic neck pain and postoperative kyphosis, and high fusion rates among a veteran population of heavy smokers. PMID: 22035103 [PubMed - as supplied by publisher] (Source: Journal of Neurosurgery.Spine)

Severe cervical scoliosis in the fetus

Prenatal Diagnosis — Wed, 26 Oct 2011 04:00:00 +0100

ConclusionOur patients suggest that connective tissue diseases or heterotaxy may be important risk factors for the development of severe cervical scoliosis. There were no significant long‐term complications directly related to cervical scoliosis. Copyright © 2011 John Wiley & Sons, Ltd. (Source: Prenatal Diagnosis)

School screening and point prevalence of adolescent idiopathic scoliosis in 4000 Norwegian children aged 12 years.

Scoliosis — Mon, 24 Oct 2011 04:00:00 +0100

CONCLUSION:The point prevalence of AIS in 12-year old children is in agreement or slightly lower than previous studies. The screening model employed demonstrates acceptable sensitivity and specificity and low referral rates.Screening at the age of 12 years only was not effective for detecting patients with indication for brace treatment. (Source: Scoliosis)

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The nitric oxide pathway participates in lordosis behavior induced by central administration of leptin

Neuropeptides — Mon, 24 Oct 2011 04:00:00 +0100

Abstract: Intracerebroventricular (icv) administration of leptin facilitates lordosis behavior in ad libitum-fed, estrogen-primed rats. The cellular mechanism involved in this response is unknown. The present study tested the hypothesis that the nitric oxide-guanylyl cyclase, cGMP-dependent protein kinase (PKG) pathway is involved in the facilitation of lordosis behavior induced by the central administration of leptin. We tested the importance of the nitric oxide/cGMP pathway for lordosis stimulation by either icv infusion of a nitric oxide synthase inhibitor (L-NAME) or a nitric oxide-dependent, soluble guanylyl cyclase inhibitor (ODQ) 30min before leptin administration (1μg). This dose of leptin reliably induced lordosis behavior in ovariectomized estradiol benzoate treated rats. The lo...

A genome-wide association study identifies common variants near LBX1 associated with adolescent idiopathic scoliosis

Nature Genetics — Sun, 23 Oct 2011 04:00:00 +0100

Authors: Yohei Takahashi, Ikuyo Kou, Atsushi Takahashi, Todd A Johnson, Katsuki Kono, Noriaki Kawakami, Koki Uno, Manabu Ito, Shohei Minami, Haruhisa Yanagida, Hiroshi Taneichi, Taichi Tsuji, Teppei Suzuki, Hideki Sudo, Toshiaki Kotani, Kota Watanabe, Kazuhiro Chiba, Naoya Hosono, Naoyuki Kamatani, Tatsuhiko Tsunoda, Yoshiaki Toyama, Michiaki Kubo, Morio Matsumoto & Shiro Ikegawa Adolescent idiopathic scoliosis is a pediatric spinal deformity affecting 2–3% of school-age children worldwide. Genetic factors have been implicated in its etiology. Through a genome-wide association study (GWAS) and replication study involving a total of 1,376 Japanese females with adolescent idiopathic scoliosis and 11,297 female controls, we identified a locus at chromosome 10q24.31 associated with a...

Posterolateral versus circumferential instrumented fusion for monosegmental lumbar degenerative disc disease using an expandable cage

European Journal of Orthopaedic Surgery and Traumatology — Fri, 21 Oct 2011 05:46:47 +0100

Conclusions Our findings suggest that 360° fusion offers better sagittal radiological restoration associated with circumferential fusion. However, this difference seemed not to have any medium-term clinical impact. The use of expandable cage was associated with low PLIF-related complications compared to conventional cages. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00590-011-0890-yAuthors Panagiotis Korovessis, Orthopaedic Department, General Hospital ‘Agios Andreas’, 1 Tsertidou str, 26224 Patras, GreeceThomas Repantis, Orthopaedic Department, General Hospital ‘Agios Andreas’, 1 Tsertidou str, 26224 Patras, GreeceAndreas Baikousis, Orthopaedic Department, General Hospital of Messolonghi, Messolonghi, GreecePanagiotis Iliopou...

Fetal Spine Findings on MRI and Associated Outcomes in Children With Open Neural Tube Defects

American Journal of Roentgenology — Fri, 21 Oct 2011 04:00:00 +0100

CONCLUSION. In fetuses with myelomeningoceles, higher and larger lesions on MRI were significantly associated with full-time wheelchair use. High lesion level was associated with dysphagia. The absence of a covering membrane was associated with scoliosis and high-risk bladder dysfunction. (Source: American Journal of Roentgenology)