MedWorm: Bartholin's Cyst

Assessment of Chlamydia trachomatis infection among Eastern European and West African women immigrants in South Italy

Sexually Transmitted Infections — Sun, 15 Jan 2012 05:00:00 +0100

Chlamydia trachomatis infection is the most common sexually transmitted bacterial infection with an estimated incidence of 50 million cases in the world.1 The infection may remain asymptomatic or, if not treated, can lead to severe clinical manifestations including acute urethral syndrome, urethritis, bartholinitis, cervicitis, upper genital tract infections and perihepatitis.2 Despite the recognised need for early diagnosis and treatment of C trachomatis and other curable sexually transmitted infections, the strategies for detection of these infections are currently limited, particularly in low-resource countries.3 Migration and population mixing have been shown to increase the risk of sexually transmitted diseases;4 however, the prevalence and determinants of C trachomatis infection, and...

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Bilateral Bartholin’s gland hematic cysts after cesarean delivery: an uncommon entity

Archives of Gynecology and Obstetrics — Thu, 12 Jan 2012 16:48:15 +0100

The historical evolution of the understanding of the submandibular and sublingual salivary glands

Clinical Anatomy — Sun, 18 Dec 2011 01:15:29 +0100

We describe the history and background of these political, religious, and philosophical factors. Next, we present a translation of the original texts, describing the establishment of the submandibular and sublingual salivary glands. We place these translations into historical context and comment on their naming propriety. Initially we translate the works of the 15th century anatomists. Next, we look at the discovery and description of the submandibular gland's duct by Thomas Wharton (1614–1673) in his landmark book, Adenographia sive glandularum totius corporis descriptio (Adenographia or the description of the glands of the entire body) (1656). Next, the somewhat unexpected discovery of the duct of the parotid gland by Nicholas Stenson (1638–1686) and his publication, De glandulis ori...

Vaginal Agenesis, the Hymen, and Associated Anomalies

Journal of Pediatric and Adolescent Gynecology — Fri, 04 Nov 2011 04:00:00 +0100

Conclusion: An absent hymen makes renal agenesis more likely and increases the likelihood that dilator techniques will fail. This condition appears to be associated with reports of long-term problems with poor lubrication that are potentially related to the absence of the peri-hymenal Bartholin’s glands. (Source: Journal of Pediatric and Adolescent Gynecology)

Nodular hyperplasia of Bartholin's gland: case reports and literature review

Jornal Brasileiro de Patologia e Medicina Laboratorial — Fri, 04 Nov 2011 02:45:57 +0100

The Bartholin's gland (BG) may develop several tumoral lesions such as BG duct cysts, carcinomas, hyperplasias, and adenomas. BG nodular hyperplasias (NHs) are uncommon, and few cases have been reported in the literature. Specific criteria for the distinction between adenomas and hyperplasias have been recently established. Several questions on possible etiologies and appropriate medical approach still remain. Therefore, this work comprises three case reports of NH and an extensive literature reviewA glândula de Bartholin (GB) pode ser sede de várias lesões tumorais, como cistos do ducto da GB, carcinomas, hiperplasias e adenomas. A hiperplasia nodular (HN) da GB é uma lesão rara e poucos casos foram relatados na literatura. Recentemente, critérios específicos estabeleceram a difere...

Characteristics of the pain observed in the focal vulvodynia syndrome (VVS)

Medical Hypotheses — Mon, 31 Oct 2011 04:00:00 +0100

Abstract: Symptoms and signs of patients with focal vulvodynia or vulvo-vestibulitis syndrome (VVS) are variable in location and severity. It is not known whether the location of the most severe pain in the vestibulum is linked to the complaints and perhaps a different entity. A clinical gut feeling suggests that two distinct varieties of focal vulvodynia may be either focused at 2 points (5 and 7 o′ clock) or at 4 points (5, 7, 1 and 11 o′ clock).A questionnaire was filled out by 30 women with focal vulvodynia during 147 visits and checked for completeness by an independent study nurse. Another investigator to evaluated the clinical signs of VVS, blinded to the patients history or complaints. The visual analogue score (VAS) of pain experienced upon attempt of sexual contact was used a...

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Hematological features in adolescents with periodontitis

Clinical Oral Investigations — Tue, 18 Oct 2011 15:58:56 +0100

Abstract The aim of this study was to assess whether adolescent cases of periodontitis present with different hemogram findings than control subjects. This case–control study comprised 87 adolescent cases presenting with clinical attachment loss ≥3 mm in at least two teeth and 73 control subjects. Blood samples were obtained by venipuncture and analyzed in an Abbott Cell-Dyn 3,500 hematology analyzer for values of white blood cells and red blood cells, hemoglobin, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red-cell distribution width, platelets, and mean platelet volume. Hematocrit values were obtained using volume fractions read from capillary tubes. The associations between log-transformed hemogram variables ...

Cellular blue nevus of the vulva mimicking Bartholin’s gland abscess in a 15-year-old girl: a case report

Archives of Gynecology and Obstetrics — Tue, 20 Sep 2011 05:50:03 +0100

Conclusion CBN should be considered in the differential diagnosis of vulvar masses in adolescent period. Content Type Journal ArticleCategory General GynecologyPages 1-3DOI 10.1007/s00404-011-2088-2Authors Mustafa Yamazhan, Department of Obstetrics and Gynecology, Aegean Obstetrics and Gynaecology Education and Research Hospital, Gaziler St., No 468, 35120 Izmir, TurkeyIbrahim Egemen Ertas, Department of Obstetrics and Gynecology, Aegean Obstetrics and Gynaecology Education and Research Hospital, Gaziler St., No 468, 35120 Izmir, TurkeyGulsen Kandiloglu, Depatment of Pathology, Ege University Medical Faculty, Izmir, TurkeyMehmet Ozeren, Department of Obstetrics and Gynecology, Aegean Obstetrics and Gynaecology Education and Research Hospital, Gaziler St., No 468, 35120 ...

Pedunculated Angiomyofibroblastoma of the Vulva: Case Report and Review of the Literature

Clinical and Developmental Immunology — Sat, 17 Sep 2011 06:57:57 +0100

We report the first case of pedunculated AMFB of the vulva occurring in a young woman of 21 years old and involving the left labia minora. After excluding the most common diseases, pedunculated AMFB should be part of differential diagnosis in the workup of any pedunculated vulvar mass even in young women with a lesion involving the labia minora. We reviewed the literature and summarized all reported cases. (Source: Clinical and Developmental Immunology)

Complicated grief and need for professional support in family caregivers of cancer patients in palliative care: a longitudinal cohort study

Supportive Care in Cancer — Sun, 04 Sep 2011 10:47:39 +0100

Conclusions The results suggest that a substantial number of family caregivers of diseased palliative care patients are at risk of developing CG and depression following their loss. While early identification of those at risk of developing CG could be helpful, the risk assessment of professionals may lack in precision. The results indicate that bereavement services could be utilized in a more targeted and perhaps more efficient manner. Guidelines for bereavement planning in palliative care are indicated. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00520-011-1260-3Authors Mai-Britt Guldin, Research Unit for General Practice, Aarhus University, Bartholin’s Allé 2, 8000 Aarhus, DenmarkPeter Vedsted, Research Unit for General Practice,...

Withholding or withdrawing therapy in intensive care units: an analysis of collaboration among healthcare professionals

Intensive Care Medicine — Mon, 29 Aug 2011 16:00:29 +0100

Conclusion Nurses, intensivists and primary physicians differ in their perception of collaboration and other aspects of withholding and withdrawing therapy practises at the ICU. Multi-disciplinary patient conferences, nurse involvement in the decision-making process, and guidelines for withholding and withdrawing therapy are recommended. Content Type Journal ArticleCategory Legal and Ethical IssuesPages 1-10DOI 10.1007/s00134-011-2345-7Authors Hanne Irene Jensen, Department of Anaesthesiology, Vejle Hospital, (V66), Kabbeltoft 25, 7100 Vejle, DenmarkJette Ammentorp, Health Services Research Unit, Lillebaelt Hospital/IRS University of Southern Denmark, Skovvangen 2-8, 6000 Kolding, DenmarkMogens Erlandsen, Department of Biostatistics, Aarhus University, Building 1261...

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Rectovaginal fistula as a complication to a bartholin gland excision.

Obstetrics and Gynecology — Sat, 30 Jul 2011 11:49:20 +0100

We present a rectovaginal fistula occurring after an excision of a Bartholin gland. PMID: 21768863 [PubMed - in process] (Source: Obstetrics and Gynecology)

Bilateral diffuse uveal melanocytic proliferation associated with the recurrence of a Bartholin gland carcinoma

British Journal of Ophthalmology — Wed, 18 May 2011 23:00:00 +0100

Case A 55-year-old woman presented in our department with progressive loss of vision for 3 months and severe neovascular glaucoma. Five years ago, owing to typical proliferative diabetic retinopathy, she had been treated with panretinal photocoagulation. She had been under observation because of type 2 diabetes mellitus since without abnormalities. Sudden neovascular glaucoma and elevated intraocular pressure required transscleral cyclophotocoagulation and cryocoagulation of the peripheral retina 2 months previously. One year previously, she underwent cataract surgery after rapid but typical cortical and nuclear cataract progression. On examination, best corrected visual acuity was light perception and intraocular pressure was 35 mm Hg in both eyes. Slit lamp examination sho...

Pathology of Vulvar Neoplasms

Surgical Pathology Clinics — Tue, 01 Mar 2011 00:00:00 +0100

Abstract: Carcinoma of the vulva is an uncommon malignant neoplasm (approximately one-fifth as frequent as cervical cancer) and represents 4% of all genital cancers in women. Approximately two-thirds of cases occur in women older than 60 years, and squamous cell carcinoma is the most common histologic type. Several different subtypes of squamous cell carcinoma have been described in the vulva; however, in terms of etiology, pathogenesis, and histologic features, most carcinomas belong to one of two categories: keratinizing squamous cell carcinomas associated with chronic inflammatory skin disorders, and basaloid or warty carcinomas related to infection with high oncogenic risk human papillomaviruses. Glandular neoplasms of the vulva arise from the vulvar apocrine sweat glands (papillary hi...

HbA1c and cardiovascular risk score identify people who may benefit from preventive interventions: a 7 year follow-up of a high-risk screening programme for diabetes in primary care (ADDITION), Denmark

Diabetologia — Tue, 22 Feb 2011 06:56:51 +0100

Conclusion/interpretation In a population-based high risk screening programme in primary care, HbA1c ≥ 6.0% combined with an elevated cardiovascular risk assessment (SCORE ≥ 5) can feasibly be used to identify those who may benefit from preventive lifestyle intervention and/or polypharmacy. Trial registration ClinicalTrials.gov NCT 00237549. Funding The study received unrestricted grants from Novo Nordisk, Novo Nordisk Scandinavia, Astra Denmark, Pfizer Denmark, GlaxoSmithKline Pharma Denmark, Servier Denmark and HemoCue Denmark. Content Type Journal ArticlePages 1-9DOI 10.1007/s00125-011-2077-9Authors T. Lauritzen, Department of General Practice, School of Publich Health, Aarhus University, Bartholins Allé 2, DK 80...

Protective effect of intra-peritoneal epinephrine on postoperative renal function after cisplatin-based intra-peritoneal intra-operative chemotherapy

European Journal of Obstetrics, Gynecology, and Reproductive Biology — Fri, 21 Jan 2011 00:00:00 +0100

Conclusions: Transient acute renal dysfunction after cisplatin-based IPC associated with cytoreductive surgery is frequent and intra-peritoneal epinephrine plays a protective role. (Source: European Journal of Obstetrics, Gynecology, and Reproductive Biology)

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Bartholin's Gland Squamous Cell Carcinoma, a Rare Vulvar Neoplasm

Journal of Diagnostic Medical Sonography — Wed, 01 Dec 2010 00:00:00 +0100

Squamous cell carcinoma of the vaginal Bartholin’s glands is a rare vulvar neoplasm affecting predominantly postmenopausal women. This case report presents a woman in her early 50s with a firm mass in the posterior vagina. Surgical biopsy revealed the mass to be a poorly differentiated squamous cell carcinoma with probable direct invasion of the rectum. (Source: Journal of Diagnostic Medical Sonography)

New ELISA approach based on coiled-coil interactions.

Journal of Immunological Methods — Wed, 22 Sep 2010 23:00:00 +0100

Authors: Liberelle B, Bartholin L, Boucher C, Murschel F, Jolicoeur M, Durocher Y, Merzouki A, De Crescenzo G The de novo designed heterodimeric E/K coiled-coil system has been previously demonstrated to be an excellent capture/dimerization system applicable to various needs in both biotechnology and pharmaceutical fields. Those include controlled protein dimerization, capture, purification and Western blot detection. We here report the development of a new generation of ELISA test based on coiled-coil interactions for the direct quantitation of coil-tagged epidermal growth factor (EGF). The new approach was evaluated for its specificity, plate storability and reusability as well as for convenience when compared to commercially available systems. Our results show a similar affinity/sen...

Novel small molecule drugs inhibit tumor cell metabolism and show potent anti-tumorigenic potential

Cancer Chemotherapy and Pharmacology — Sat, 18 Sep 2010 05:49:02 +0100

Conclusion In conclusion, these small molecules, built on a 1,3-dihydroindole-2-one scaffold, elicit strong anti-proliferative and cytotoxic activity, and importantly, a strong anti-tumorigenicity is observed in in vivo xenograft models of human breast, ovary, prostate and pancreatic cancers encouraging the translation of this class of compounds into the clinic. Content Type Journal ArticleDOI 10.1007/s00280-010-1453-3Authors Christina Trojel-Hansen, XPU Bartholin, Rigshospitalet 3731, TopoTarget A/S, Copenhagen Biocenter, Ole Maaløesvej 5, 2200 Copenhagen, DenmarkKamille Dumong Erichsen, TopoTarget A/S, Symbion, Fruebjergvej 3, 2100 Copenhagen, DenmarkMette Knak Christensen, TopoTarget A/S, Symbion, Fruebjergvej 3, 2100 Copenhagen, DenmarkPeter Buhl Jensen, TopoTa...

[Angiomyofibroblastoma of the right ischiorectal fosa.]

Cirugia y Cirujanos — Wed, 01 Sep 2010 00:00:00 +0100

Conclusions: Angiomyofibroblastoma must be considered in the differential diagnosis of vulvovaginal tumors because its treatment differs from others lesions of that region. PMID: 21219818 [PubMed - as supplied by publisher] (Source: Cirugia y Cirujanos)

HbA1c as predictor of all-cause mortality in individuals at high risk of diabetes with normal glucose tolerance, identified by screening: a follow-up study of the Anglo–Danish–Dutch Study of Intensive Treatment in People with Screen-Detected Diabetes in Primary Care (ADDITION), Denmark

Diabetologia — Tue, 10 Aug 2010 19:06:00 +0100

Conclusions/interpretation HbA1c level in people with NGT and at high risk of diabetes was clearly associated with increased all-cause mortality. Content Type Journal ArticleDOI 10.1007/s00125-010-1867-9Authors M. V. Skriver, Department of General Practice, School of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, DenmarkK. Borch-Johnsen, Steno Diabetes Center, Gentofte, DenmarkT. Lauritzen, Department of General Practice, School of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, DenmarkA. Sandbaek, Department of General Practice, School of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, Denmark Journal DiabetologiaOnline ISSN 1432-0428Print ISSN 0012-186X (Source: Diabetologia)

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Aggressive angiomyxoma of vulva and vagina: a series of three cases and review of literature

Archives of Gynecology and Obstetrics — Fri, 02 Jul 2010 19:40:48 +0100

Conclusion Angiomyxoma of vulva and vagina refers to a rare disease; diagnosis is not at all clinical, thus, cases presenting as bartholin cyst, benign vulval lesions and vaginal wall cysts should have complete radiological work up before excision, as pre-diagnosis can change the treatment modality and prognosis of patient. Content Type Journal ArticleCategory Gynecologic OncologyDOI 10.1007/s00404-010-1575-1Authors Krishna Dahiya, Pt.BDS, PGIMS Department of Obstetrics and Gynecology Rohtak 74-R, Model Town Rohtak 124001 Haryana IndiaShaveta Jain, Pt.BDS, PGIMS Department of Obstetrics and Gynecology Rohtak 74-R, Model Town Rohtak 124001 Haryana IndiaNirmala Duhan, Pt.BDS, PGIMS Department of Obstetrics and Gynecology Rohtak 74-R, Model Town Rohtak 124001 Haryana I...

Primary neuroendocrine carcinoma of the Bartholin's gland: Magnetic resonance imaging findings with pathologic correlation

European Journal of Radiology Extra — Tue, 25 May 2010 23:00:00 +0100

We present a case of primary neuroendocrine carcinoma arising in Bartholin's gland and for the first time discuss the MRI appearances of this tumour. (Source: European Journal of Radiology Extra)

HERVs in Neuropathogenesis

Journal of NeuroImmune Pharmacology — Tue, 27 Apr 2010 07:02:38 +0100

Abstract In humans, exogenous retroviruses are known to cause immunodeficiency and neurological disease. While endogenous retroviruses are firmly established pathogens in other species, the human endogenous retroviruses (HERVs) may well be considered as emerging pathogens. HERVs also exhibit complex interactions with exogenous retroviruses and herpesviruses. Two neurological disorders in particular are associated with HERVs: multiple sclerosis (MS) and schizophrenia. HERV-H/F and HERV-W are specifically activated both in the circulation and the central nervous system (CNS) in a majority of MS patients, and particularly, the envelopes (env transcription and Env proteins) appear strongly associated with disease activity. Interferon beta (IFN-β) therapy is well-established f...

Urethral Diverticula in Women: Discrepancies Between Magnetic Resonance Imaging and Surgical Findings

The Journal of Urology — Sun, 18 Apr 2010 23:00:00 +0100

Conclusions: In cases clinically suspicious for urethral diverticulum magnetic resonance imaging had a 24.4% error rate. Serious consequences are failure to detect cancer and suboptimal treatment for urethral diverticulum. The reason for the high magnetic resonance imaging accuracy rate in other series may be that in the absence of radiological confirmation some surgeons may choose not to perform surgery. Magnetic resonance imaging is useful to assess urethral diverticula but physicians should be aware of its limitations. (Source: The Journal of Urology)

What Is A Bartholin's Cyst? What Causes A Bartholin's Cyst?

Women's Health / OBGYN News From Medical News Today — Fri, 09 Apr 2010 07:00:00 +0100

A Bartholin's cyst, also called a Bartholin's duct cyst, is a small growth just inside the opening of a woman's vagina. The Bartholin's glands secrete fluid that helps lubricate the vagina. They are located on each side of the vaginal opening. Sometimes the openings of these glands become obstructed, causing fluid to back up into the gland. This causes the swelling called a Bartholin cyst... (Source: Women's Health / OBGYN News From Medical News Today)

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Elimination of the plasmid bacterial backbone in site-directed transgenesis.

BioTechniques — Wed, 31 Mar 2010 23:00:00 +0100

Authors: Jakobsen J, Mikkelsen J, Nielsen A For cellular and animal transgenesis, FLP- and Cre-recombinase gene capture systems are highly effective to provide stable integration of a donor plasmid carrying the transgene cassette of interest into an engineered genomic locus in a given cell line. However, in many protocols, the entire plasmid bacterial backbone is integrated along with the transgene cassette. Here, we present a very simple yet highly efficient method for excluding plasmid bacterial backbone integration. The transgene cassette, including a single FLP recognition target site, is specifically amplified by PCR, and the resulting DNA ligated into minicircles can serve as donor DNA in FLP-mediated recombination. Interestingly, the elimination of the bacterial backbone increas...

Lymphocele Mimicking Bartholin Cyst

Journal of Pediatric and Adolescent Gynecology — Tue, 30 Mar 2010 14:02:20 +0100

Background: Bartholin cysts are a common lower genital tract lesion in young females. Diagnosis is clinical with a limited differential of abscess and malignancy. This is the first case report of a vascular malformation, lymphatic type (lymphangioma) mimicking a persistent Bartholin cyst. (Source: Journal of Pediatric and Adolescent Gynecology)

Justice and the allocation of healthcare resources: should indirect, non-health effects count?

Medicine, Health Care and Philosophy — Sun, 21 Mar 2010 05:49:47 +0100

Abstract Alternative allocations of a fixed bundle of healthcare resources often involve significantly different indirect, non-health effects. The question arises whether these effects must figure in accounts of the conditions under which a distribution of healthcare resources is morally justifiable. In this article we defend a Scanlonian, affirmative answer to this question: healthcare resource managers should sometimes select an allocation which has worse direct, health-related effects but better indirect, nonhealth effects; they should do this when the interests served by such a policy are more urgent than the healthcare interests better served by an alternative allocation. We note that there is a prima facie case for the claim that such benefits (and costs) are relevan...

Sulphated galactosylceramide

Diabetologia — Wed, 24 Feb 2010 06:51:39 +0100

Content Type Journal ArticleCategory LetterDOI 10.1007/s00125-010-1690-3Authors K. Buschard, Bartholin Instituttet Rigshospitalet section 3733, Blegdamsvej 9 DK-2100 Copenhagen Denmark Journal DiabetologiaOnline ISSN 1432-0428Print ISSN 0012-186X (Source: Diabetologia)

Bartholin cyst: Treatment depends on size, pain, infection

MayoClinic.com Full Feed — Wed, 20 Jan 2010 02:45:00 +0100

Bartholin cyst — Comprehensive overview covers symptoms, causes, treatment of this vaginal condition. (Source: MayoClinic.com Full Feed)

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Birthweight and the risk of childhood-onset type 1 diabetes: a meta-analysis of observational studies using individual patient data

Diabetologia — Sun, 10 Jan 2010 07:12:00 +0100

Conclusions/interpretation Children who are heavier at birth have a significant and consistent, but relatively small increase in risk of type 1 diabetes. Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-009-1648-5Authors C. R. Cardwell, Queen’s University Belfast Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences Grosvenor Road Belfast BT12 6BJ UKL. C. Stene, Norwegian Institute of Public Health Division of Epidemiology Oslo NorwayG. Joner, Oslo University Hospital Oslo Diabetes Research Centre Oslo NorwayE. A. Davis, The University of Western Australia Telethon Institute for Child Health Research, Centre for Child Health Research Perth WA AustraliaO. Cinek, Charles University The 2nd Medical School Prague Czech RepublicJ. Ro...

Bartholin gland carcinoma.

Indian Journal of Pathology and Microbiology — Fri, 01 Jan 2010 00:00:00 +0100

Authors: Khanna G, , Azad K PMID: 20090260 [PubMed - in process] (Source: Indian Journal of Pathology and Microbiology)

A rapid strategy to detect the recombined allele in LSL‐TβRICA transgenic mice

genesis — Fri, 01 Jan 2010 00:00:00 +0100

(Source: genesis)

Bartholin Cyst - Facts and Information

Disabled World — Mon, 14 Dec 2009 16:27:12 +0100

A woman's Bartholin glands are located at the entrance to her vagina, one on each side. The glands are small, and may not be seen or felt when they are healthy. The function of the glands is to secrete fluid onto the mucosal, or inner, surface of the labia surrounding the vagina. (Source: Disabled World)

Emergence of cell-wall protease in the Streptococcus thermophilus population.

Applied and Environmental Microbiology — Fri, 13 Nov 2009 00:00:00 +0100

Authors: Delorme C, Bartholini C, Bolotine A, Ehrlich SD, Renault P Streptococcus thermophilus is perceived as a recently emerged food bacterium that evolved from a commensal ancestor by loss and gain of functions. Here, we provide data allowing a better understanding of this evolutionary scheme. A MLST approach that we developed showed that S. thermophilus diverges significantly from its potential ancestors of the salivarius group and displays a low allelic variability, confirming its likely recent emergence. An analysis of the origin and dissemination of prtS gene was carried out within this evolutionary scheme. This gene encodes protease that allows a better growth in milk, by facilitating the casein breakdown for amino acid supply. S. thermophilus protease exhibits 95% identity to ...

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Vulvar lipomas in children: an analysis of 7 cases

Journal of Pediatric Surgery — Wed, 30 Sep 2009 23:00:00 +0100

Conclusions: Vulvar lipomas in children tend to occur on the right side, especially the right anterolateral side. It is necessary to differentiate this tumor from an inguinal hernia. Radiologic studies such as ultrasonography, computed tomography, and magnetic resonance imaging are useful for making the proper diagnosis. Surgical excision is the treatment of choice. (Source: Journal of Pediatric Surgery)

Treatment of Bartholin Abscesses

The Journal of Emergency Medicine — Mon, 21 Sep 2009 23:00:00 +0100

We read with interest the article by Drs. Kushnir and Mosquera on the treatment of Bartholin abscesses (). The simple ring catheter works well in our experience (). Typically, we use a softer catheter for the ring, but we've also used butterfly tubing in a pinch. (Source: The Journal of Emergency Medicine)

Pitfalls in Abdominal Diffusion-Weighted Imaging: How Predictive is Restricted Water Diffusion for Malignancy

American Journal of Roentgenology — Sun, 20 Sep 2009 23:00:00 +0100

CONCLUSION. Restricted diffusion is generally considered to be associated with malignant tumors because of the high cellularity of these tumors. However, in interpretation of diffusion-weighted images, it should be kept in mind that a number of benign lesions, as many as 22% in our cohort, can exhibit restricted diffusion on images with high b values, thus mimicking malignant lesions. (Source: American Journal of Roentgenology)

Perineal leiomyoma mimicking complex Bartholin mass

International Urogynecology Journal — Tue, 15 Sep 2009 20:49:53 +0100

We report the case of a 47-year-old woman with perineal leiomyomas mimicking Bartholin's gland mass according to the preoperative magnetic resonance imaging (MRI) findings. Leiomyomas in the vulvar region should be differentiated from complicated Bartholin’s gland cysts and preoperative MRI findings may be misleading. The complete surgical excision should be the choice of treatment Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00192-009-0998-3Authors Onder Koc, Abant Izzet Baysal University Department of Gynecology and Obstetrics, Faculty of Medicine Bolu TurkeyNeriman Sengul, Abant Izzet Baysal University Medical Faculty Department of General Surgery 14280-Gölköy Bolu TurkeySafiye Gurel, Abant Izzet Baysal University Department of Radiology, Faculty of Medicine ...

Primary vulvar Ewing's sarcoma/primitive neuroectodermal tumor in a post-menopausal woman: A case report.

Pathology, Research and Practice — Sun, 02 Aug 2009 23:00:00 +0100

We describe the case of a 52-year-old woman who was admitted to our hospital for the local excision of a 4cm vulvar mass, originally thought to be a Bartholin's gland cyst. It was subsequently found to consist of small round cells positive for anti-CD99 antibody, thus suggesting a diagnosis of ES/pPNET. The demonstration of EWSR1 gene translocations by means of fluorescent in situ hybridization excluded small-cell carcinoma, squamous cell carcinoma of the small type, Merkel cell carcinoma, and lymphoblastic lymphoma. After surgery, the patient received six cycles of polychemotherapy and radiotherapy; she is still alive and well after 1 year of follow-up. Our findings underline the crucial role of molecular biology techniques in the differential diagnosis of small round cell tumors in these...

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Methicillin-Resistant Staphylococcus aureus Bacteremia and Chorioamnionitis After Recurrent Marsupialization of a Bartholin Abscess.

Obstetrics and Gynecology — Fri, 24 Jul 2009 05:45:49 +0100

CONCLUSION:: Our case and the literature suggest that it may be prudent to consider MRSA when contemplating the possibility of chorioamnionitis in the presence of intact fetal membranes, especially in gravidas with recurrent admissions or minor surgical procedures or who are hospital staff. PMID: 19622965 [PubMed - in process] (Source: Obstetrics and Gynecology)

Mismatch repair defective breast cancer in the hereditary nonpolyposis colorectal cancer syndrome

Breast Cancer Research and Treatment — Mon, 06 Jul 2009 16:17:33 +0100

Abstract Whether or not breast cancer can be a feature of the hereditary nonpolyposis colorectal cancer (HNPCC) syndrome has been debated. In order to clarify if defective mismatch repair (MMR) may indeed play a role in breast cancer, we used the Danish HNPCC register to identify all breast cancers that occurred in MMR gene mutation carriers. In total, 20 female mutation carriers were diagnosed with breast cancer at mean 50 years of age. These tumors were predominantly ductal carcinomas with extensive lymphocytic reactions in 8/14 evaluated tumors. MMR protein immunostaining showed loss of expression of MLH1, MSH2 or MSH6 corresponding to the mutations identified in 7 of the 16 cases investigated, and these tumors were diagnosed at mean 50 (33–66) years of age. ...

Bartholin's, vulval and perineal abscesses

Best Practice & Research. Clinical Obstetrics & Gynaecology — Sun, 05 Jul 2009 23:00:00 +0100

Perineal infections are a common presenting complaint in women attending acutely to a gynaecology department. Specifically, Bartholin's abscesses can occur in approximately 2% of women. Conservative versus surgical approaches to manage these infections aims to reduce the need for hospital admission. We summarise the literature on the diagnosis and management of Bartholin's and other types of perineal infections and abscesses specific to gynaecology. (Source: Best Practice & Research. Clinical Obstetrics & Gynaecology)

Linkage of atopic dermatitis to chromosomes 4q22, 3p24 and 3q21

Human Genetics — Thu, 11 Jun 2009 14:04:44 +0100

Abstract Atopic dermatitis (AD) is a common, itchy skin disease of complex inheritance characterized by dermal and epidermal inflammation. The heritability is considerable and well documented. To date, four genome scans have examined the AD phenotype, showing replicated linkage at 3p26-22, 3q13-21 and 18q11-21. Our previous AD scan showed evidence of linkage to loci at 3p and 18q, and furthermore at 4p15-14. In order to further investigate the genetic basis of AD, we collected and analysed a new Danish family sample consisting of 130 AD sib pair families (555 individuals including 295 children with AD). AD was diagnosed after clinical examination, AD severity was scored and specific IgE was determined. A linkage scan of chromosome 3, 4 and 18 was performed using 91 microsat...

Necrotizing Pneumonia Caused by Panton-Valentine Leucocidin-Producing Staphylococcus aureus Originating from a Bartholin's Abscess

Infectious Diseases in Obstetrics and Gynecology — Tue, 09 Jun 2009 20:06:24 +0100

Conclusions. S. aureus, in particular PVL-positive strains, should be considered when a young, immunocompetent person develops a fulminant necrotizing pneumonia. Minor infections—such as Bartholin's abscess—can precede this life-threating syndrome. Bactericidal antistaphylococcal antibiotics are recommended for treatment, and surgical procedures may become necessary. (Source: Infectious Diseases in Obstetrics and Gynecology)

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iNKT cell development is orchestrated by different branches of TGF-{beta} signaling

The Journal of Experimental Medicine — Mon, 08 Jun 2009 04:00:00 +0100

Invariant natural killer T (iNKT) cells constitute a distinct subset of T lymphocytes exhibiting important immune-regulatory functions. Although various steps of their differentiation have been well characterized, the factors controlling their development remain poorly documented. Here, we show that TGF-β controls the differentiation program of iNKT cells. We demonstrate that TGF-β signaling carefully and specifically orchestrates several steps of iNKT cell development. In vivo, this multifaceted role of TGF-β involves the concerted action of different pathways of TGF-β signaling. Whereas the Tif-1 branch controls lineage expansion, the Smad4 branch maintains the maturation stage that is initially repressed by a Tif-1/Smad4-independent branch. Thus, these three differen...

Management of Bartholin Duct Cysts and Abscesses: A Systematic Review.

Obstetrical & Gynecological Survey — Sat, 23 May 2009 07:28:59 +0100

Page: 395DOI: 10.1097/OGX.0b013e31819f9c76Authors: Wechter, Mary Ellen MD, MPH *; Wu, Jennifer M. MD, MPH +; Marzano, David MD ++; Haefner, Hope MD [S][P] (Source: Obstetrical & Gynecological Survey)

Bartholin's abscess caused by hypermucoviscous Klebsiella pneumoniae.

Journal of Medical Microbiology — Fri, 01 May 2009 04:00:00 +0100

We describe here what we believe to be the first reported case of hypermucoviscous K. pneumoniae causing a superficial Bartholin's abscess in the absence of systemic involvement. PMID: 19369531 [PubMed - in process] (Source: Journal of Medical Microbiology)

Novel Technique for Management of Bartholin Gland Cysts and Abscesses

The Journal of Emergency Medicine — Wed, 29 Apr 2009 01:09:28 +0100

Conclusion: This technique may be used as an alternative to placement of a Word catheter for management of Bartholin gland abscess or cyst. (Source: The Journal of Emergency Medicine)

Incidence of Bartholin's duct occlusion after superficial localized vestibulectomy

American Journal of Obstetrics and Gynecology — Sun, 19 Apr 2009 23:00:00 +0100

Conclusion: The incidence of duct ostium occlusion after superficial modified vestibulectomy was 9%, and only half had symptoms. Methods of surgical treatment of the occlusion are compared. (Source: American Journal of Obstetrics and Gynecology)

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Low-grade Epithelial-Myoepithelial Carcinoma of Bartholin Gland: Report of 2 Cases of a Distinctive Neoplasm Arising in the Vulvovaginal Region.

International Journal of Gynecological Pathology — Sat, 18 Apr 2009 06:10:22 +0100

Page: 286DOI: 10.1097/PGP.0b013e31818e1040Authors: McCluggage, W. Glenn F.R.C.Path.; Aydin, N. Engin M.D.; Wong, Newton A. C. S. F.R.C.Path.; Cooper, Kumarasen F.R.C.Path. (Source: International Journal of Gynecological Pathology)

Bartholinitis caused by Streptococcus pneumoniae: case report and review of literature.

Indian Journal of Pathology and Microbiology — Wed, 01 Apr 2009 04:00:00 +0100

Authors: Parvathi S, Imara AS, Thoduka TG Most of the Bartholin's gland abscesses have been thought to be caused by colonizing micro-organisms of the perineal region. We encountered an interesting case of acute Bartholins abscess caused by Streptococcus pneumoniae in a primigravida. The abscess was incised and drained. The patient was treated with Cefuroxime. This case is presented for its rarity. PMID: 19332936 [PubMed - in process] (Source: Indian Journal of Pathology and Microbiology)

Prospective Randomized Study of Marsupialization versus Silver Nitrate Application in the Management of Bartholin Gland Cysts and Abscesses

The Journal of Minimally Invasive Gynecology — Sun, 01 Mar 2009 05:00:00 +0100

Conclusion: Marsupialization and silver nitrate application seem to be equally effective management methods in Bartholin cyst and abscesses, however, silver nitrate favors complete healing with less scar formation. (Source: The Journal of Minimally Invasive Gynecology)

Lymphoepithelioma-Like Carcinoma of the Bartholin Gland.

The American Journal of Dermatopathology — Sun, 23 Nov 2008 08:22:14 +0100

Page: 586DOI: 10.1097/DAD.0b013e31817fd387Authors: Kacerovska, Denisa MD, PhD *; Nemcova, Jana MSc *; Petrik, Roman MD +; Michal, Michal MD *; Kazakov, Dmitry V MD, PhD * (Source: The American Journal of Dermatopathology)

Liver metastasis in a case of adenoid cystic carcinoma of the Bartholin’s gland: a rare presentation

Archives of Gynecology and Obstetrics — Sun, 09 Nov 2008 09:57:40 +0100

Content Type Journal ArticleCategory ErratumDOI 10.1007/s00404-008-0823-0Authors Shohreh Shahabi, Albert Einstein College of Medicine and Montefiore Medical Center Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Women’s Health Bronx NY 10461 USALisa M. Nathan, Albert Einstein College of Medicine and Montefiore Medical Center Division of Gynecologic Oncology, Department of Obstetrics and Gynecology and Women’s Health Bronx NY 10461 USACharu Chanana, Bronx Lebonan Hospital Department of Obstetrics and Gynecology New York USAWendy S. Garrett, Dana Farber Cancer Institute Department of Medical Oncology Boston MA 02115 USAWenxin Zheng, University of Arizona College of Medicine Department of Pathology, Arizona Cancer Center Tucson AZ 85724 USAThomas J. Ruthe...

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Bartholin's abscess arising within hidradenoma papilliferum of the vulva: a case report

Cases Journal — Wed, 29 Oct 2008 04:00:00 +0100

Conclusion: We present what we believe to be the first case of Bartholin's abscess arising in hidradenoma papilliferum and its clinical significance. (Source: Cases Journal)

Liver metastasis in a case of adenoid cystic carcinoma of the Bartholin’s gland: a rare presentation

Archives of Gynecology and Obstetrics — Thu, 18 Sep 2008 06:35:06 +0100

We present the first reported case of Adenoid cystic carcinoma of the Bartholin’s gland with metastasis to the liver. Discussion There is no consensus on the treatment of adenoid cystic carcinoma of the Bartholin’s gland. Wide local excision and/or vulvectomy and radiotherapy are advocated for treatment of this cancer. There is not much data on treatment of metastasis and it varies according to site. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00404-008-0771-8Authors Shohreh Shahabi, 3411 Wayne Avenue Bronx New York NY USALisa Marie Nathan, 3411 Wayne Avenue Bronx New York NY USACharu Chanana, 3411 Wayne Avenue Bronx New York NY USAWendy Garett, 3411 Wayne Avenue Bronx New York NY USAW. Zheng, 3411 Wayne Avenue Bronx New York NY USAT. J. Ru...

Necrotizing Pneumonia Caused by Panton-Valentine Leucocidin-Producing Staphylococcus aureus Originating from a Bartholin's Abscess

Infectious Diseases in Obstetrics and Gynecology — Tue, 29 Jul 2008 13:15:42 +0100

MR Findings of a Giant Bartholin's Duct Cyst.

Magnetic Resonance in Medical Sciences : MRMS — Wed, 09 Jul 2008 14:03:03 +0100

We describe the case of a 63-year-old woman with a large Bartholin's duct cyst that showed high signal intensity on T(1)- and T(2)-weighted magnetic resonance (MR) images. Although Bartholin's duct cyst is the most frequent cystic lesion of the vulva, such a giant cyst is rare. PMID: 18603842 [PubMed - in process] (Source: Magnetic Resonance in Medical Sciences : MRMS)

Vulvovaginal Infections, Cervicitis and Bartholin's Cyst (Suparna Chhibber MBBS, MD)

Family Medicine Digital Resources Library (FMDRL) Recently Uploaded — Mon, 12 May 2008 04:00:00 +0100

Overview of the etiology of vulvovaginal infections vaginitis and cervicitis for Residency didactic teaching. (Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded)

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[Vulvar vestibulitis syndrome: a clinicopathological study of 14 cases]

Annales de Dermatologie et de Cenereologie — Thu, 01 May 2008 04:00:00 +0100

We report the same pattern in our study. Moreover, we observed some exocytosis into the epithelium of minor vestibular glands and the excretory duct. This aspect has not been reported to date, further supporting the individual nature of this entity. PMID: 18457722 [PubMed - in process] (Source: Annales de Dermatologie et de Cenereologie)

Vulvar leiomyosarcoma in Bartholin’s gland area: a case report and literature review

Archives of Gynecology and Obstetrics — Fri, 25 Apr 2008 07:52:13 +0100

Conclusion Any vulvar lesion with unusual characteristics or insidious evolution in labia majora or Bartholin’s glands area should be carefully and promptly studied. This is particularly important in order to perform an effective surgical treatment in cases of leiomyosarcoma. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00404-008-0652-1Authors F. González-Bugatto, University Hospital “Puerta del Mar” Department of Obstetrics and Gynecology Avenida Ana de Viya 21 11009 Cádiz SpainM. J. Añón-Requena, University Hospital “Puerta del Mar” Department of Pathology Cádiz SpainM. A. López-Guerrero, University Hospital “Puerta del Mar” Department of Obstetrics and Gynecology Avenida Ana de Viya 21 11009 Cádiz SpainJ. M. Báez-Perea, Univers...

Bartholin's Cyst Marsupialization

The Journal of Sexual Medicine — Thu, 24 Apr 2008 16:13:25 +0100

The Journal of Sexual Medicine, Volume 5, Issue 5, Page 1053-1056, May 2008. (Source: The Journal of Sexual Medicine)

Pattern of non-venereal dermatoses of female external genitalia in South India.

Dermatol Online J — Thu, 06 Mar 2008 20:16:22 +0100

This study highlights the importance of diagnosing non-venereal dermatoses and refutes the general misconception that all vulval itching is the result of fungal infection. The two most common causes of vulval itching observed in the study were lichen sclerosus and lichen simplex chronicus. PMID: 18319018 [PubMed - in process] (Source: Dermatol Online J)

Caesarean section is associated with an increased risk of childhood-onset type 1 diabetes mellitus: a meta-analysis of observational studies

Diabetologia — Fri, 22 Feb 2008 16:00:06 +0100

Conclusions/interpretation This analysis demonstrates a 20% increase in the risk of childhood-onset type 1 diabetes after Caesarean section delivery that cannot be explained by known confounders. Content Type Journal ArticleCategory Meta AnalysisDOI 10.1007/s00125-008-0941-zAuthors C. R. Cardwell, Queen’s University Belfast Department of Epidemiology and Public Health, School of Medicine and Dentistry Grosvenor Road Belfast BT12 6BJ UKL. C. Stene, Norwegian Institute of Public Health Division of Epidemiology Oslo NorwayG. Joner, Aker and Ullevål University Hospitals Diabetes Research Centre Oslo NorwayO. Cinek, Charles University Second Medical School Prague Czech RepublicJ. Svensson, Steno Diabetes Centre Gentofte DenmarkM. J. Goldacre, Oxford University Department...

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Adenoid cystic carcinoma of the Bartholin’s gland: a rare tumor unmarked by persistent vulvar pain in a postmenopausal women

Archives of Gynecology and Obstetrics — Tue, 19 Feb 2008 15:31:22 +0100

Discussion In cases of persistent vulvar pain without swelling, complete vulvovaginal evaluation should be done to prevent delay in diagnosis of Bartholin’s gland cancer. Treatment modality must be tailored to each patient, though there is no consensus on the treatment. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00404-008-0601-zAuthors Özgür Şahincioğlu, Ankara University School of Medicine Department of Obstetrics and Gynecology Cebeci 06100 Ankara TurkeyBülent Berker, Ankara University School of Medicine Department of Obstetrics and Gynecology Cebeci 06100 Ankara TurkeyMete Güngör, Ankara University School of Medicine Department of Obstetrics and Gynecology Cebeci 06100 Ankara TurkeyDuygu Kankaya, Ankara University School of Medicine Depart...

Bartholin cyst

MayoClinic.com Full Feed — Sat, 19 Jan 2008 06:00:00 +0100

— Comprehensive overview covers symptoms, causes, treatment of this vaginal condition.Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)

[How I do ... Bartholin gland cystectomy.]

Gynecologie, Obstetrique & Fertilite — Thu, 29 Nov 2007 05:00:00 +0100

Authors: Eglin G PMID: 18061507 [PubMed - as supplied by publisher] (Source: Gynecologie, Obstetrique & Fertilite)

AF10-dependent transcription is enhanced by its interaction with FLRG.

Biology of the Cell — Wed, 19 Sep 2007 01:10:33 +0100

Conclusions. Our present study provides novel insights into the function of the nuclear form of the FLRG protein, which is revealed as a novel regulator of transcription. The nuclear isoform of FLRG lacks an intrinsic transactivation domain, but enhances AF10-mediated transcription, probably through promoting the homo-oligomerization of AF10, thus facilitating the recruitment of co-activators. PMID: 17868029 [PubMed - in process] (Source: Biology of the Cell)

Vulvar endometriosis in surgical scar after excision of the Bartholin gland: report of a case

Archives of Gynecology and Obstetrics — Wed, 12 Sep 2007 07:08:11 +0100

Abstract Endometriosis is a common gynecologic disease characterized by growth of endometrial glands and stroma outside the endometrium. Implants are most commonly found in the pelvis but can occur in many other sites. Vulvar involvement of endometriosis is extremely rare. A case of vulvar endometriosis is presented. Endometriosis was infiltrating the subcutaneous scar tissue of left labia minora after cystectomy of Bartholin gland for abscess that has recurred several times despite office-based treatment. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00404-007-0458-6Authors Alessandro Buda, University of Milano-Bicocca, Bassini Hospital Department of Obstetrics and Gynecology Cinisello Balsamo Milan ItalyLuisa Ferrari, University of Milano-Bicocca, Bassin...

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Silencing of FLRG, an Antagonist of Activin, Inhibits Human Breast Tumor Cell Growth

Cancer Research — Wed, 01 Aug 2007 04:00:00 +0100

Activin, a member of the transforming growth factor ß (TGFß) superfamily, regulates diverse processes, such as cellular growth and differentiation. There is increasing evidence that TGFß and its signaling effectors are key determinants of tumor cell behavior. Loss of sensitivity to TGFß-induced growth arrest is an important step toward malignancy. We previously characterized FLRG as an extracellular antagonist of activin. Here, we show that activin-induced growth inhibition is altered in FLRG-expressing breast cancer lines. Silencing FLRG induced growth inhibition, which is reversible upon addition of exogenous FLRG. We showed that FLRG silencing effects resulted from restoration of endogenous activin functions as shown by increased levels of phosphorylated smad2 an...

Bartholin's Gland Hyperplasia in a Young Woman

Karger Publishers — Wed, 01 Aug 2007 00:28:08 +0100

Gynecol Obstet Invest 2008;65:18-20 (DOI:10.1159/000106500) (Source: Karger Publishers)

Nodular Hyperplasia of the Bartholin Gland: A Clinicopathological Study of Two Cases, Including Detection of Clonality by HUMARA.

The American Journal of Dermatopathology — Sun, 22 Jul 2007 00:46:42 +0100

Page: 385DOI: 10.1097/DAD.0b013e31806f54b3Authors: Kazakov, Dmitry V MD, PhD *; Curik, Romuald MD +; Vanecek, Tomas PhD *; Mukensnabl, Petr MD *; Michal, Michal MD * (Source: The American Journal of Dermatopathology)

Bartholin's gland abscess in a neonate: a case report.

Canadian Urological Association Journal — Fri, 01 Jun 2007 04:00:00 +0100

We report the second case of a Bartholin's gland abscess in a female neonate. PMID: 18542776 [PubMed - in process] (Source: Canadian Urological Association Journal)

F-18 FDG PET-CT in a Rare Case of Bartholin's Gland Undifferentiated Carcinoma Managed With Chemoradiation and Interstitial Brachytherapy.

Clinical Nuclear Medicine — Tue, 22 May 2007 21:46:14 +0100

Page: 498DOI: 10.1097/RLU.0b013e318053783dAuthors: Imperiale, Alessio MD *; Heymann, Steve MD +; Claria, Marcelo MD *; Cimarelli, Sebastien MD *; Sellem, Dorra Ben MD *; Goetz, Christian MD, PhD *; Onea, Alina MD ++; Blondet, Cyrille MD *; Constantinesco, Andre MD, PhD * (Source: Clinical Nuclear Medicine)

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Identification of NF-kappaB responsive elements in follistatin related gene (FLRG) promoter.

Gene — Tue, 15 May 2007 04:00:00 +0100

Authors: Bartholin L, Guindon S, Martel S, Corbo L, Rimokh R Follistatin related gene (FLRG) has been previously identified from a chromosomal translocation observed in a B-cell chronic lymphocytic leukemia (B-CLL). FLRG (alternative names: follistatin-related protein, FSRP/follistatin-like-3, FSTL3) is a secreted glycoprotein highly similar to follistatin. Like follistatin, FLRG is involved in the regulation of various biological effects through its binding to members of the transforming growth factor beta (TGFbeta) superfamily such as activin A and myostatin. We have previously shown that TGFbeta and activin A are potent inducers of FLRG transcriptional activation through the Smad proteins. Using a biochemical approach, we investigated whether tumor necrosis factor alpha (TNFalpha) c...

Primary treatment of Bartholin’s gland carcinoma with radiation and chemoradiation: a report on ten consecutive cases

International Journal of Gynecological Cancer — Thu, 10 May 2007 19:42:31 +0100

International Journal of Gynecological Cancer Volume 17, Issue 3, Page 661-667, May 2007. (Source: International Journal of Gynecological Cancer)

AF10 dependent transcription is enhanced by its interaction with FLRG.

Biology of the Cell — Thu, 03 May 2007 04:00:00 +0100

Conclusions: Our study provides novel insights into the function of the nuclear form of FLRG protein which is revealed as a novel regulator of transcription. The nuclear isoform of FLRG lacks an intrinsic transactivation domain, but enhances AF10-mediated transcription probably through promoting the homo-oligomerization of AF10, thus facilitating the recruitment of coactivators. PMID: 17477845 [PubMed - as supplied by publisher] (Source: Biology of the Cell)

Varianten der Lage der Bartholinischen Drüsen

Anatomy and Embryology — Sat, 31 Mar 2007 08:46:02 +0100

Ohne Zusammenfassung Content TypeJournal Article JournalAnatomy and EmbryologyOnline ISSN 1432-0568Print ISSN 0340-2061 Journal VolumeVolume 69 Journal IssueVolume 69, Numbers 4-6 / July, 1923 (Source: Anatomy and Embryology)

The role of mycoplasmas in pregnancy outcome.

Best Practice & Research. Clinical Obstetrics & Gynaecology — Sat, 17 Mar 2007 04:00:00 +0100

Authors: Taylor-Robinson D Mycoplasma hominis was isolated from a Bartholin's gland abscess 70 years ago, and ureaplasmas were isolated from the genital tract about 20 years later. Subsequently, reports incriminating mycoplasmas in the known adverse outcomes of pregnancy have been legion. Without doubt these genital mycoplasmas are able to invoke an inflammatory response and take part in the cascade of events that culminates in preterm birth. Their role in this and other conditions is becoming clearer, but controversy remains due mainly to investigators often ignoring bacterial vaginosis, with its complex of bacteria, and failing to disentangle their role from that of the genital mycoplasmas. This is a theme that will be highlighted in this chapter, in which an attempt is made to indic...

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The simple outpatient management of Bartholin's abscess using the Word catheter: A preliminary study

The Australian and New Zealand Journal of Obstetrics and Gynaecology — Thu, 08 Mar 2007 15:10:33 +0100

The Australian and New Zealand Journal of Obstetrics and Gynaecology Volume 47, Issue 2, Page 137-140, Apr 2007. (Source: The Australian and New Zealand Journal of Obstetrics and Gynaecology)

Immunology's first priority dispute-An account of the 17th-century Rudbeck-Bartholin feud.

Cellular Immunology — Mon, 22 Jan 2007 16:39:02 +0100

Authors: Ambrose CT Modern immunology has been notably free of public disputes over credit for major discoveries in this discipline. But the early recognition of the lymphatic system witnessed two examples of heated priority feuds. The first in the 17th-century concerned the greater anatomical organization of the system, while the second in the 18th-century concerned its function. This essay reviews the earlier of the two disputes, in which a Swedish medical student (Ole Rudbeck) charged a respected Danish Professor (T. Bartholin) with plagiarism and antedating his observations. Thus ethical issues in immunology predate modern times. How this discipline reached this point in its history is another focus of this essay and also an excuse to review briefly the anatomy of the lymphatic sys...

Primary treatment of Bartholin's gland carcinoma with radiation and chemoradiation: a report on ten consecutive cases

International Journal of Gynecological Cancer — Tue, 12 Dec 2006 14:38:14 +0100

Online early issue. (Source: International Journal of Gynecological Cancer)

Old and new perspectives in the management of high-risk, locally advanced or recurrent, and metastatic vulvar cancer.

Critical Reviews in Oncology Hematology — Fri, 01 Dec 2006 05:00:00 +0100

Authors: Gadducci A, Cionini L, Romanini A, Fanucchi A, Genazzani AR During the last decades there has been a continuing evolution in the surgical approach of squamous cell carcinoma of the vulva that has been traditionally treated with radical vulvectomy and bilateral inguinal-femoral lymphadenectomy. Patients with T1 tumour are usually treated with radical local excision, if the lesion is unifocal and the remainder of the vulva is normal. Patients with T1a disease have no risk of groin metastases and do not need lymphadenectomy, whereas those with T1b disease need ipsilateral inguinal-femoral lymphadenectomy if the lesion is lateral, and bilateral lymphadenectomy if the lesion is midline. Modifications of the surgical technique of deep femoral lymphadenectomy and the mapping of senti...

Serum testosterone, DHEAS, and prolactin levels in patients with a Bartholin’s abscess

Archives of Gynecology and Obstetrics — Thu, 12 Oct 2006 09:31:05 +0100

This study examines Prolactin and Androgen concentrations in 15 women with a Bartholin’s gland abscess and in 15 matched normal controls. The Dehydroepiandrosterone sulfate concentrations were higher in the Bartholin’s abscess group as compared to the concentrations in the control group [7.0±3.1 mmol/l versus 4.3±1.3 mmol/l (p (Source: Archives of Gynecology and Obstetrics)

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The contributions of the Bartholin family to the study and practice of clinical anatomy

Clinical Anatomy — Thu, 21 Sep 2006 11:25:01 +0100

Between 1585 and 1738, four members of the celebrated Bartholin family made significant contributions to anatomical science and medicine. Caspar Bartholin (the elder), two of his sons (Thomas and Rasmus), and his grandson (Caspar the younger) all served on the medical faculty of the University of Copenhagen, and helped to gain international acclaim for the institution. Over three generations, the Bartholins challenged traditional ideas about science and the human body, and discovered anatomical structures and phenomena that would prove crucial to the practice of modern medicine. Clin. Anat., 2006. © 2006 Wiley-Liss, Inc. (Source: Clinical Anatomy)

The problem of accurate initial diagnosis of Bartholin's gland carcinoma resulting in delayed treatment and aggressive course of the disease

International Journal of Gynecological Cancer — Tue, 13 Jun 2006 15:47:09 +0100

International Journal of Gynecological Cancer Volume 16, Issue 3, Page 1469-1472, May 2006 (Source: International Journal of Gynecological Cancer)

Nodular hyperplasia of Bartholin's gland

Pathology — Sat, 03 Jun 2006 06:00:00 +0100

(Source: Pathology)

Cellular angiofibroma of the vulva: case report with clinicopathological and immunohistochemistry study.

Sao Paulo Medical Journal — Thu, 01 Sep 2005 06:00:00 +0100

We describe a case in a 51-year-old woman whose preoperative diagnosis was confounded with Bartholin's glandular cyst. The neoplasia was well delimited and made up of three characteristic components: fusiform cells forming small fascicles, numerous blood vessels and adipose tissue interspersed between the fusiform cells. The stroma cells were positive for vimentin and negative for CD34, protein S-100, actin and desmin. The differential diagnoses for this tumor include aggressive angiomyxoma, angiomyofibroblastoma, lipoma of fusiform cells, solitary fibrous tumor, perineurioma and leiomyoma. PMID: 16358102 [PubMed - indexed for MEDLINE] (Source: Sao Paulo Medical Journal)