MedWorm: Bipolar

Melatonin receptors are anatomically organized to modulate transmission specifically to cone pathways in the retina of Xenopus laevis

The Journal of Comparative Neurology — Thu, 09 Feb 2012 01:21:34 +0100

AbstractConfocal image of the relative distribution of the Mel1b melatonin receptor (green) and the ON bipolar cell marker guanine nucleotide binding protein alpha, Go α (red) in the retina of Xenopus laevis. Mel1b receptor immunoreactivity is absent from the cell bodies of ON bipolar cells, identifying the Mel1b receptorimmunoreactive bipolar cells as OFF bipolar cells. The Journal of Comparative Neurology, Volume 520, Number 6, pages 1115–1127. (Source: The Journal of Comparative Neurology)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Abortion doesn't up risk of mental illness relapse

Reuters: Health — Wed, 08 Feb 2012 21:21:51 +0100

NEW YORK (Reuters Health) - In women with a history of mental illness such as schizophrenia and bipolar disorder, getting an abortion does not increase their chances of landing in a psychiatric facility again, suggests a new study from Denmark. (Source: Reuters: Health)

Positive Topline Phase 3 Results for Acute Mania DrugPositive Topline Phase 3 Results for Acute Mania Drug

Medscape Today Headlines — Wed, 08 Feb 2012 19:20:08 +0100

Results from a phase 3 clinical trial show an investigational antipsychotic may hold promise in the treatment of acute mania associated with bipolar 1 disorder. Medscape Medical News (Source: Medscape Today Headlines)

Organizational motifs for ground squirrel cone bipolar cells

The Journal of Comparative Neurology — Wed, 08 Feb 2012 05:00:00 +0100

AbstractIn daylight vision, parallel processing starts at the cone synapse. Cone signals flow to On and Off bipolar cells, which are further divided into types according to morphology, immunocytochemistry, and function. The axons of the bipolar cell types stratify at different levels in the inner plexiform layer (IPL), and can interact with costratifying amacrine and ganglion cells. These interactions endow the ganglion cell types with unique functional properties. The wiring that underlies the interactions between bipolar, amacrine, and ganglion cells is poorly understood. It may be easier to elucidate this wiring if organizational rules can be established. We identify 13 types of cone bipolar cells in the ground squirrel, 11 of which contact contiguous cones with the possible exception o...

Temperaments linked to clinical features and course in bipolar I disorder

MedWire News - Psychiatry — Tue, 07 Feb 2012 14:12:28 +0100

Research suggests that cyclothymic and hyperthymic temperaments are associated with differences in clinical features in patients with bipolar I disorder, such as number of hospitalizations, disease course, family history, and comorbid disorders. (Source: MedWire News - Psychiatry)

Chinese version of MDQ effective for BD screening

MedWire News - Bipolar Disorder — Tue, 07 Feb 2012 14:12:27 +0100

The Chinese version of the Mood Disorder Questionnaire is an effective screening tool for bipolar disorder among patients who have experienced a major depressive episode, say researchers. (Source: MedWire News - Bipolar Disorder)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Customized adherence enhancement for individuals with bipolar disorder receiving antipsychotic therapy

NeLM - Mental Health — Tue, 07 Feb 2012 05:00:00 +0100

Source: Psychiatric Services Area: Evidence > Medicines Management > References Objective: A 3-month prospective trial of a psychosocial intervention - customised adherence enhancement (CAE) - was conducted with 43 medication-nonadherent individuals with bipolar disorder. Methods: CAE modules were administered as indicated by a screen that identifies reasons for nonadherence. The primary outcome was change in adherence to mood-stabilising medications as measured by the Tablet Routines Questionnaire and pill counts. Secondary outcomes included change in symptoms, measured by the Hamilton Rating Scale for Depression (HAM-D), Young Mania Rating Scale (YMRS), and Brief Psychiatric Rating Scale (BPRS). Results: Participants completed 76% of sessions. ...

The Gentle Self: How to Overcome Your Difficulties with Depression, Anxiety, Shyness, and Low Self-Esteem

Psych Central — Mon, 06 Feb 2012 20:35:16 +0100

I think everyone’s a little narcissistic. We all have moments when we wish everyone would be more like us—when we get upset that no one seems to care about what we are feeling. We also often put others ahead of ourselves and deny ourselves the satisfaction of saying “I need to do this for me.” If either of these becomes an extreme, psychologists may diagnose it as Narcissistic Personality Disorder. The Gentle Self by Gerti Schoen addresses the second type of narcissist. Drawing on her own experiences and her observations of others, Schoen explains exactly what a “gentle self” is. This type of narcissist puts others ahead of themselves because the narcissist feels that he or she is unworthy of love or respect. I can definitely relate to the gentle self. Schoen spen...

Solution-processable small molecules as efficient universal bipolar host for blue, green and red phosphorescent inverted OLEDs

RSC - J. Mater. Chem. latest articles — Mon, 06 Feb 2012 17:38:26 +0100

J. Mater. Chem., 2012, Advance ArticleDOI: 10.1039/C2JM16463A, PaperJiangshan Chen, Changsheng Shi, Qiang Fu, Fangchao Zhao, Yue Hu, Yuling Feng, Dongge MaVacuum-evaporable small molecules of SPPO13 and TCTA are employed as a solution-processed bipolar co-host for high efficiency inverted phosphorescent OLEDs.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Mater. Chem. latest articles)

Differentiating between Bipolar Disorder Types I and II: Results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). - Bega S, Schaffer A, Goldstein B, Levitt A.

SafetyLit: All (Unduplicated) — Mon, 06 Feb 2012 11:54:53 +0100

OBJECTIVE: Bipolar Disorder I (BD I) and Bipolar Disorder II (BD II) vary considerably, with differences in symptomatology, management and prognosis. For patients with depression, the distinction between BD I and BD II is not always apparent, and hinges on... (Source: SafetyLit: All (Unduplicated))

Age at onset versus family history and clinical outcomes in 1,665 international bipolar-I disorder patients. - Baldessarini RJ, Tondo L, Vazquez GH, Undurraga J, Bolzani L, Yildiz A, Khalsa HM, Lai M, Lepri B, Lolich M, Maffei PM, Salvatore P, Faedda GL, Vieta E, Mauricio T.

SafetyLit: All (Unduplicated) — Mon, 06 Feb 2012 11:54:53 +0100

Early onset in bipolar disorder (BPD) has been associated with greater familial risk and unfavorable clinical outcomes. We pooled data from seven international centers to analyze the relationships of family history and symptomatic as well as functional mea... (Source: SafetyLit: All (Unduplicated))

MedWorm Sponsor Message: Find the best January Sales in the UK.

Highly Sensitive to Noise?

About.com Bipolar Disorder — Mon, 06 Feb 2012 06:00:00 +0100

On our Main Forum, Drop-In Jane writes: "I was wondering, are any of you highly sensitive to noise? I'm moving, and part of the reason is that the walls here are ...Read Full Post (Source: About.com Bipolar Disorder)

Influence of Patient Race and Ethnicity on Clinical Assessment in Patients With Affective Disorders [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions African American individuals exhibited significantly higher rates of clinical diagnoses of schizophrenia than non-Latino white subjects, even after controlling for covariates such as serious affective disorder. (Source: Archives of General Psychiatry)

Differences in the Circuitry-Based Association of Copy Numbers and Gene Expression Between the Hippocampi of Patients With Schizophrenia and the Hippocampi of Patients With Bipolar Disorder [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion Insertions and deletions of genomic DNA in -aminobutyric acid cells at a key locus of the hippocampal circuit are reflected in transcriptional changes in GAD67 regulation that are circuitry-based and diagnosis-specific. (Source: Archives of General Psychiatry)

Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions The findings of this study support the long-term safety and antidepressant efficacy of subcallosal cingulate DBS for TRD and suggest equivalent safety and efficacy for TRD in patients with BP. Trial Registration clinicaltrials.gov Identifier: NCT00367003 (Source: Archives of General Psychiatry)

What Is Schizoaffective Disorder?

About.com Bipolar Disorder — Mon, 06 Feb 2012 05:00:00 +0100

Schizoaffective disorder is one of the least understood mental illnesses. Authorities differ on the description of the illness, and to make matters worse, the European and American definitions are quite a bit different. In the US, patients with schizoaffective disorder have symptoms of both schizophrenia and bipolar disorder - but there is a lot more to it. Misdiagnosis is common, but fortunately, even when the condition isn't properly diagnosed, treatment may still be effective. Read the best available information, what the problems in diagnosis are, and why treatment doesn't depend on the right diagnosis: What Is Schizoaffective Disorder?.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Learn more or join the conversation! NEWSLETTER | FORUM | ...

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Hospitalization for psychiatric disorders before and after onset of unprovoked seizures/epilepsy

Neurology — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion: The increased rate of psychiatric comorbidity predating and succeeding seizure onset indicates a bidirectional relationship and common underlying mechanisms for psychiatric disorders and epilepsy. (Source: Neurology)

Chinese version of MDQ effective for BD screening

MedWire News - Psychiatry — Sat, 04 Feb 2012 14:44:52 +0100

What Are the Causes of Bipolar Disorder?

About.com Bipolar Disorder — Sat, 04 Feb 2012 05:00:00 +0100

In Part 2 of Bipolar for Beginners, we take a look at what scientists believe are the causes - genetic, physical and psychological - of bipolar disorder. For whatever reason you want to know more about this illness, here is information in clear English that will answer some of your questions about things like whether bipolar is inherited, the part brain chemistry plays in bipolar, and how researchers believe it all fits together. (Source: About.com Bipolar Disorder)

Erratum: Conversion from unipolar to bipolar resistance switching by inserting TaO layer in Pt/TaO/Pt cells [Appl. Phys. Lett. 98, 183507 (2011)]

Applied Physics Letters — Sat, 04 Feb 2012 01:21:21 +0100

H. K. Yoo, S. B. Lee, J. S. Lee, S. H. Chang, M. J. Yoon et al. Abstract not available. [Appl. Phys. Lett. 100, 059901 (2012)] published Wed Feb 1, 2012. (Source: Applied Physics Letters)

Separation of Electrical and Optical Energy Gaps for Constructing Bipolar Organic Wide Bandgap Materials

RSC - Chem. Commun. latest articles — Fri, 03 Feb 2012 17:53:59 +0100

Chem. Commun., 2012, Accepted ManuscriptDOI: 10.1039/C2CC17682C, CommunicationYuguang Ma, Dehua Hu, Fangzhong Shen, He Liu, Ping Lu, Ying Lv, Dandan LiuElectrical and optical energy gaps separated strategy is put forward for the design of organic wide bandgap semiconductors. This new principle could achieve an optimization of wide bandgap (both high...The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Chem. Commun. latest articles)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Who Is Left Out of the DSM-5 Debate? Of Course, Consumers

Psychology Today Parenting Center — Fri, 03 Feb 2012 17:50:12 +0100

To my ears, the current DSM-5 debate comes down to the question of who has the right to decide when an individual and a family have suffered enoughread more (Source: Psychology Today Parenting Center)

Metabolic Side Effects Such As Obesity And Diabetes Caused By Antipsychotic Medications

Health News from Medical News Today — Fri, 03 Feb 2012 09:00:00 +0100

In 2008, roughly 14.3 million Americans were taking antipsychotics - typically prescribed for bipolar disorder, schizophrenia, or a number of other behavioral disorders - making them among the most prescribed drugs in the U.S. Almost all of these medications are known to cause the metabolic side effects of obesity and diabetes, leaving patients with a difficult choice between improving their mental health and damaging their physical health... (Source: Health News from Medical News Today)

[Original Articles] Fertility Treatment Response: Is It Better to Be More Optimistic or Less Pessimistic?

Psychosomatic Medicine — Fri, 03 Feb 2012 05:00:00 +0100

Conclusions Being pessimistic may be a risk factor for IVF treatment failure. Future research should attempt to delineate the biological and behavioral mechanisms by which pessimism may negatively affect treatment outcomes. (Source: Psychosomatic Medicine)

Radio Frequency Ablation vs. Bipolar Umbilical Cord Coagulation in the Management of Complex Monochorionic Pregnancies

Ultrasound in Obstetrics and Gynecology — Fri, 03 Feb 2012 05:00:00 +0100

CONCLUSION: Despite the smaller caliber of the instrument, RFA is not associated with a decrease in the overall complication rate for selective termination procedures. The technique used for selective termination should still be determined by technical considerations but patients should be informed of the survival associated with each technique. Copyright © 2012 ISUOG. Published by John Wiley & Sons, Ltd. (Source: Ultrasound in Obstetrics and Gynecology)

Radio Frequency Ablation vs. Bipolar Umbilical Cord Coagulation in the Management of Complex Monochorionic Pregnancies.

The Ultrasound Review of Obstetrics and Gynecology — Fri, 03 Feb 2012 05:00:00 +0100

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Nitrous oxide: Manic relapse: case report

Reactions — Thu, 02 Feb 2012 18:34:27 +0100

(Source: Reactions)

Recovery of visual function in patient with melanoma-associated retinopathy treated with surgical resection and interferon-beta

Documenta Ophthalmologica — Thu, 02 Feb 2012 18:16:47 +0100

We report on a 33-year-old woman who was treated for a cutaneous malignant melanoma on a left finger by surgical resection and chemotherapy including local injections of interferon-beta in 2007. In March 2009, the melanoma had metastasized to her left hand, and she underwent metastasectomy and monthly local injections of interferon-beta. She developed shimmering vision, photopsia, blurred vision, and night blindness in her left eye in April 2009 and visited our clinic. At our initial examination, her best-corrected visual acuity was 1.5 OD and 1.2 OS, and ophthalmoscopy showed that the retina appeared normal in both eyes. However, there was a mild narrowing of retinal arteries in the left eye. Humphrey field analyzer (HFA) showed a reduction in retinal sensitivity within the central ...

Circulating concentrations, cerebral output of the CINC-1 and blood–brain barrier disruption in Wistar rats after pneumococcal meningitis induction

European Journal of Clinical Microbiology and Infectious Diseases — Thu, 02 Feb 2012 18:15:51 +0100

Abstract Pneumococcal meningitis is a severe infectious illness of the central nervous system (CNS), with high rates of lethality and morbidity, being that the microorganism and the host’s inflammatory response are responsible for cerebral complications. Moreover, the blood–brain barrier (BBB) itself secretes cytokines and, because of the bipolar nature of the BBB, these substances can be secreted into either the CNS compartment or in the blood, so patients with acute bacterial meningitis frequently develop sepsis. Therefore, the aim of this study was to evaluate the cytokine/chemokine levels in different vessels and the BBB integrity after pneumococcal meningitis induction. Wistar rats were infected with Streptococcus pneumoniae, and the BBB integrity was investigated ...

New Study May End 2 Decades Of Suspicion: Does Borna Disease Virus Cause Mental Illness?

Health News from Medical News Today — Thu, 02 Feb 2012 08:00:00 +0100

Over the past 30 years, numerous studies have linked Borna disease virus (BDV) with mental illnesses such as bipolar disorder, schizophrenia, anxiety disorder and dementia. Genetic fragments and antibodies to this RNA virus, which causes behavior disorders in a range of mammals and birds, have been found to be prevalent in psychiatric patients, but study results have been inconsistent. Now, the first blinded, case-control study to examine this issue finds no association between the virus and psychiatric illness... (Source: Health News from Medical News Today)

Radiofrequency volumetric tissue reduction of the inferior turbinate in a sheep model

The Laryngoscope — Thu, 02 Feb 2012 05:00:00 +0100

Conclusions:The sheep model is useful for study of both the anatomic and histopathologic effects of endonasal procedures. Standard endoscopic instruments and acoustic rhinometry can be used in this model with reproducible results. In this pilot animal study, radiofrequency devices for inferior turbinate reduction demonstrated greater preservation of normal nasal mucosal respiratory epithelium when compared to monopolar electrosurgery. (Source: The Laryngoscope)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Loss of Function of the Cik1/Kar3 Motor Complex Results in Chromosomes with Syntelic Attachment That Are Sensed by the Tension Checkpoint

PLoS Genetics — Thu, 02 Feb 2012 05:00:00 +0100

by Fengzhi Jin, Hong Liu, Ping Li, Hong-Guo Yu, Yanchang Wang The attachment of sister kinetochores by microtubules emanating from opposite spindle poles establishes chromosome bipolar attachment, which generates tension on chromosomes and is essential for sister-chromatid segregation. Syntelic attachment occurs when both sister kinetochores are attached by microtubules from the same spindle pole and this attachment is unable to generate tension on chromosomes, but a reliable method to induce syntelic attachments is not available in budding yeast. The spindle checkpoint can sense the lack of tension on chromosomes as well as detached kinetochores to prevent anaphase onset. In budding yeast Saccharomyces cerevisiae, tension checkpoint proteins Aurora/Ipl1 kinase and centromere-localize...

Psychotherapy benefits youth with first-episode psychotic mania

MedWire News - Bipolar Disorder — Thu, 02 Feb 2012 00:00:00 +0100

The addition of psychotherapy to treatment as usual may help reduce symptoms of depression and overall symptom severity in young people who have experienced a first episode of psychotic mania, say researchers. (Source: MedWire News - Bipolar Disorder)

Psychosocial functioning reduced in multiple-episode BD patients

MedWire News - Psychiatry — Wed, 01 Feb 2012 10:50:58 +0100

Patients with bipolar disorder who have experienced multiple mood episodes show poorer psychosocial functioning over time than first-episode patients, Spanish study results show. (Source: MedWire News - Psychiatry)

Seizure risk increased before and after psychiatric hospitalization

MedWire News - Bipolar Disorder — Wed, 01 Feb 2012 10:50:57 +0100

Results from a Swedish study suggest the risk for unprovoked epileptic seizures is significantly increased before and after hospitalization for psychiatric disorders. (Source: MedWire News - Bipolar Disorder)

Simultaneous Population Pharmacokinetic Modeling of Ketamine and Three Major Metabolites in Patients with Treatment‐Resistant Bipolar Depression

British Journal of Clinical Pharmacology — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: This represents the first PK analysis of (2S,6S;2R,6R)‐HNK and (R,S)‐DHNK. The results demonstrate that while norKet is the initial metabolite, it is not the main metabolite suggesting that future Ket studies should include the analysis of the major metabolites.© 2012 The Authors. British Journal of Clinical Pharmacology © 2012 The British Pharmacological Society (Source: British Journal of Clinical Pharmacology)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study

Neuropsychopharmacology — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Lobna Ibrahim, Nancy DiazGranados, Jose Franco-Chaves, Nancy Brutsche, Ioline D Henter, Phillip Kronstein, Ruin Moaddel, Irving Wainer, David A Luckenbaugh, Husseini K Manji & Carlos A Zarate Keywords: mood / anxiety / stress disorders; glutamate; depression; unipolar / bipolar; clinical pharmacology / clinical trials; ketamine; riluzole; NMDA; depression; antidepressant (Source: Neuropsychopharmacology)

Pseudocholinesterase activity in type 1 bipolar patients.

Annales de Biologie Clinique — Wed, 01 Feb 2012 05:00:00 +0100

This study aims to investigate the variation of pseudocholinesterase activity (BuChE) in bipolar patients and to explore its relation to the clinical and therapeutic characteristics of this disease. Our study included 105 patients with bipolar disorder and 100 control subjects aged 38.7 ± 12.2 and 36.4 ± 15.7 y, respectively. BuChE was determined by kinetic methods on Cobas Integra 400 plus™. Compared with controls, patients had a significantly higher pseudocholinesterase activity. Moreover, this increase was significantly associated (p = 0.001) with bipolar disorder with sensibility of 58% and specificity of 62% at threshold of 7392 IU/L. There was no significant change in pseudocholinesterase activity in relation to illness episodes and treatment, whereas the lowest...

Mapping vulnerability to bipolar disorder: a systematic review and meta-analysis of neuroimaging studies.

J Psychiatry Neurosc... — Wed, 01 Feb 2012 05:00:00 +0100

Conclusion: Accumulating structural and functional imaging evidence supports the existence of neurobiologic trait abnormalities in individuals at genetic risk for bipolar disorder at various scales of investigation. PMID: 22297067 [PubMed - as supplied by publisher] (Source: J Psychiatry Neurosc...)

Systematic review of the neural basis of social cognition in patients with mood disorders.

J Psychiatry Neurosc... — Wed, 01 Feb 2012 05:00:00 +0100

Conclusion: Further work is needed to examine the contribution of key moderator variables and to further elucidate the neural networks underlying altered social cognition in patients with mood disorders. The neural networks under lying higher-order social cognitive processes, including empathy, remain unexplored in patients with mood disorders. PMID: 22297065 [PubMed - as supplied by publisher] (Source: J Psychiatry Neurosc...)

Age at onset versus family history and clinical outcomes in 1,665 international bipolar-I disorder patients.

World Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Baldessarini RJ, Tondo L, Vazquez GH, Undurraga J, Bolzani L, Yildiz A, Khalsa HM, Lai M, Lepri B, Lolich M, Maffei PM, Salvatore P, Faedda GL, Vieta E, Mauricio T Abstract Early onset in bipolar disorder (BPD) has been associated with greater familial risk and unfavorable clinical outcomes. We pooled data from seven international centers to analyze the relationships of family history and symptomatic as well as functional measures of adult morbidity to onset age, or onset in childhood (age <12), adolescence (12-18), or adulthood (19-55 years). In 1,665 adult, DSM-IV BPD-I patients, onset was 5% in childhood, 28% in adolescence, and 53% at peak ages 15-25. Adolescent and adult onset did not differ by symptomatic morbidity (episodes/year, percentage of months ill, co-morb...

MedWorm Sponsor Message: Find the best January Sales in the UK.

Biopsychosocial Model of Hypersexuality in Adolescent Girls With Bipolar Disorder: Strategies for Intervention

Journal of Child and Adolescent Psychiatric Nursing — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: Sexual health education, improved treatment adherence, symptom monitoring, interpersonal skills training, parental involvement, and clinician education can improve hypersexual behavior in girls with BD. (Source: Journal of Child and Adolescent Psychiatric Nursing)

Cardiac Pacemakers in Electric and Magnetic Fields of 400‐kV Power Lines

Pacing and Clinical Electrophysiology : PACE — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: The electric field under a 400‐kV power line may disturb a PM. However, only one type out of several tested PMs showed a major disturbance and that was only with a unipolar electrode configuration. The risk of disturbances is therefore not deemed to be high.(PACE 2012;1–9) (Source: Pacing and Clinical Electrophysiology : PACE)

Psychosocial functioning reduced in multiple-episode BD patients

MedWire News - Bipolar Disorder — Wed, 01 Feb 2012 00:00:00 +0100

Transformation kinetics of an intrinsic bistable defect in damaged silicon

Journal of Applied Physics — Tue, 31 Jan 2012 19:51:00 +0100

R. M. Fleming, C. H. Seager, D. V. Lang, and J. M. Campbell The positions of the electronic levels of an intrinsic bistable defect have been measured using deep level transient spectroscopy (DLTS) in n- and p-type damaged silicon bipolar transistor diodes after minority carrier injection and thermal annealing. The kinetic rates observed during conversion of ... [J. Appl. Phys. 111, 023715 (2012)] published Tue Jan 31, 2012. (Source: Journal of Applied Physics)

Does Borna disease virus cause mental illness?

EurekAlert! - Social and Behavioral Science — Tue, 31 Jan 2012 05:00:00 +0100

(Columbia University's Mailman School of Public Health) Over the past 30 years, numerous studies have linked Borna disease virus with mental illnesses such as bipolar disorder, schizophrenia, anxiety disorder and dementia, but study results have been inconsistent. Now, the first blinded, case-control study to examine this issue finds no association between the virus and psychiatric illness. (Source: EurekAlert! - Social and Behavioral Science)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Cooling of the epileptic focus suppresses seizures with minimal influence on neurologic functions

Epilepsia — Tue, 31 Jan 2012 05:00:00 +0100

SummaryPurpose: Focal brain cooling is effective for suppression of epileptic seizures, but it is unclear if seizures can be suppressed without a substantial influence on normal neurologic function. To address the issue, a thermoelectrically driven cooling system was developed and applied in free‐moving rat models of focal seizure and epilepsy.Methods: Focal seizures limited to the unilateral forelimb were induced by local application of a penicillin G solution or cobalt powder to the unilateral sensorimotor cortex. A proportional integration and differentiation (PID)–controlled, thermoelectrically driven cooling device (weight of 11 g) and bipolar electrodes were chronically implanted on the eloquent area (on the epileptic focus) and the effects of cooling (20, 15, and 10°C) ...

Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder

Molecular Psychiatry — Tue, 31 Jan 2012 05:00:00 +0100

Authors: M Hornig, T Briese, J Licinio, R F Khabbaz, L L Altshuler, S G Potkin, M Schwemmle, U Siemetzki, J Mintz, K Honkavuori, H C Kraemer, M F Egan, P C Whybrow, W E Bunney & W I Lipkin (Source: Molecular Psychiatry)

Validation of the Chinese version of the "Mood Disorder Questionnaire" for screening bipolar disorder among patients with a current depressive episode

BMC Psychiatry - Latest articles — Tue, 31 Jan 2012 05:00:00 +0100

Conclusions: Our results show that the Chinese version of MDQ is a valid tool for screening BPD in a group of patients with current depressive episode on the Chinese mainland. (Source: BMC Psychiatry - Latest articles)

Lithium Toxicity - Types, Causes and Treatment

About.com Bipolar Disorder — Tue, 31 Jan 2012 05:00:00 +0100

This article describes each type, the possible symptoms, and the various treatments. (Source: About.com Bipolar Disorder)

Short‐term electrical stimulation of the lower esophageal sphincter increases sphincter pressure in patients with gastroesophageal reflux disease

Neurogastroenterology and Motility — Tue, 31 Jan 2012 05:00:00 +0100

Conclusions & Inferences Short‐term stimulation of the LES in patients with GERD significantly increases resting LESP without affecting esophageal peristalsis or LES relaxation. Electrical stimulation of the LES may offer a novel therapy for patients with GERD. (Source: Neurogastroenterology and Motility)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Nonepisodic factors may help differentiate BD subtypes

MedWire News - Psychiatry — Tue, 31 Jan 2012 00:00:00 +0100

A number of significant differences, other than manic/mixed and hypomanic episodes, may help distinguish patients with bipolar I disorder from those with bipolar II disorder, say Canadian researchers. (Source: MedWire News - Psychiatry)

Poll: What Does the Evidence Say About Bipolar Disorder and Obesity?

Psychiatric Times — Mon, 30 Jan 2012 12:00:00 +0100

Take the poll on individuals with comorbid obesity and bipolar disorder. (Source: Psychiatric Times)

New‐Onset Treatment‐Dependent Diabetes Mellitus and Hyperlipidemia Associated with Atypical Antipsychotic Use in Older Adults without Schizophrenia or Bipolar Disorder

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionUse of atypical antipsychotics in older adults for conditions other than schizophrenia and bipolar disorder was associated with incident treatment of diabetes mellitus but not of hyperlipidemia, suggesting that older adults may be susceptible to the adverse metabolic consequences of these agents. (Source: Journal of the American Geriatrics Society)

One‐year psychosocial functioning in patients in the early vs. late stage of bipolar disorder

Acta Psychiatrica Scandinavica — Mon, 30 Jan 2012 05:00:00 +0100

Conclusion: Our data give support to the model of staging in bipolar disorder, showing that the enduring neurotoxicity of repeated episodes may contribute to sustained impairment in multiple areas of psychosocial functioning. (Source: Acta Psychiatrica Scandinavica)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Effectiveness of a bipolar vessel sealant device for sealing uterine horns and bodies from dogs.

American Journal of Veterinary Research — Sun, 29 Jan 2012 12:42:52 +0100

Conclusions and Clinical Relevance-The failure pressure for both sealing techniques was high, which indicated that the VSD may be a safe instrument for sealing the uterine horn in dogs. Given the low mean bursting pressure for seals in uterine bodies with large diameters, the VSD cannot be recommended for sealing uterine bodies ≥ 9 mm in diameter. PMID: 22280394 [PubMed - in process] (Source: American Journal of Veterinary Research)

Change Proposed for Definition and Diagnosing of Cyclothymia

About.com Bipolar Disorder — Sun, 29 Jan 2012 05:00:00 +0100

The American Psychiatric Association is hard at work to produce the next version of the Diagnostic and Statistical Manual of Mental Disorders. One of the disorders that has changes proposed is Cyclothymia, a form of bipolar that comprises hypomanic episodes along with periods of depression that are not severe enough to meet the criteria for a major depressive episode. In the current edition of the DSM, the presence of mixed episodes during the first two years of illness rules out a diagnosis of Cyclothymia. In the proposed new version, this exclusion has been removed. If this revision stands, a diagnosis of Cyclothymia With Mixed Features would be possible. "With Mixed Features" is an example of a specifier. Other specifiers that could be applied to Cyclothymia under the new diagnostic g...

Cloning scientists create human brain cells

Guardian Unlimited Science — Sun, 29 Jan 2012 00:07:00 +0100

Scientists in Edinburgh who pioneered cloning have made a technological breakthrough that could pave the way for better medical treatment of mental illnesses and nerve diseasesThe news that Edinburgh scientists had created the world's first cloned mammal, Dolly the sheep, at the university's Roslin Institute made headlines around the world 16 years ago. Her birth raised hopes of the creation of a new generation of medicines – with a host of these breakthroughs occurring at laboratories in the university over the following decade.And now one of the most spectacular has taken place at Edinburgh's Centre for Regenerative Medicine, where scientists have continued to develop the technology used to make Dolly. In a series of remarkable experiments, they have created brain tissue from patients ...

The Brown University Child and Adolescent Psychopharmacology Update — Sat, 28 Jan 2012 19:11:52 +0100

AbstractNew AACAP Practice Parameter for OCDPresence of Disruptive Behaviors With Bipolar Predicts Drug ResponsePediatric Bipolar Disorder: Aripiprazole Tested as Maintenance TreatmentLisdexamfetamine Improves ADHD Symptoms/Functioning in College StudentsExpert Recommendations on Treating Aggressive YouthHigh Antipsychotic Rates in Foster CareOpen‐Label Study of Citalopram in Hospitalized TeensNo Increased Risk of Serious Heart Disease With ADHD Drugs in Young or Older AdultsCognitive Function in Adolescent Schizophrenia Following ECTImipramine for Risperidone‐Induced EnuresisSSRIs in Pregnancy: No Change in RecommendationsRecommendations Unchanged on ADHD DrugsNew Approvals (Source: The Brown University Child and Adolescent Psychopharmacology Update)

Reintegration Awards Recognize Battle Against Schizophrenia and Bipolar Disorder

Psychiatric Times — Sat, 28 Jan 2012 19:00:02 +0100

Do you know someone that has fought the brave fight against serious mental illness? They deserve recognition and applause. Do nominate them or let them know of the Reintegration Awards. (Source: Psychiatric Times)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Messengers of the Brain

About.com Bipolar Disorder — Sat, 28 Jan 2012 05:00:00 +0100

Neurotransmitters play a key role in mood disorders like bipolar and depression. When they are released to carry a message from one nerve cell to another, there are many things that can happen. (Source: About.com Bipolar Disorder)

Antidepressant Treatment for Acute Bipolar Depression: An Update

Comparative and Functional Genomics — Fri, 27 Jan 2012 14:47:07 +0100

Conclusions. Antidepressants probably have no substantial role in acute bipolar depression. However, in light of conflicting results between studies, more well-designed trials are warranted. (Source: Comparative and Functional Genomics)

Clinical and safety profiles of bipolar transurethral vaporization of the prostate in saline: A preliminary report

Asian Journal of Endoscopic Surgery — Fri, 27 Jan 2012 11:25:37 +0100

AbstractTransurethral vaporization of the prostate in saline (TURisV) is an innovative endoscopic surgical modality for the treatment of benign prostatic hyperplasia (BPH) that vaporizes prostate tissue using a uniquely designed mushroom electrode. TURisV promises instant hemostatic tissue ablation under saline irrigation and offers clinical advantages for endoscopic BPH operations. From July 2008 to February 2009, TURisV was performed in 17 cases with clinically significant BPH. Median operation time was 127.0 min and median volume of vaporized prostate tissue was 41.1 g. Median International Prostate Symptom Score improved from 20 to 4 after 12 months. Median maximum flow rate increased from 5.3 mL/s to 13.8 mL/s after 12 months. Postoperative median residual urine improved from ...

An Unusual Presentation of Primary Hyperparathyroidism: Pathological Fracture

Advances in Pharmacological Sciences — Thu, 26 Jan 2012 18:56:20 +0100

We present a case of a 54-year-old female patient who was admitted with fracture of her right femur. She underwent closed intramedullary reconstruction nailing with bipolar locking. The pathological findings confirmed the diagnosis of primary hyperparathyroidism with brown tumor. Further tests showed increased both calcium level and PTH level. A parathyroidectomy was performed. She made an uneventful recovery and was discharged to home. (Source: Advances in Pharmacological Sciences)

Obesity and Bipolar Disorder

Psychiatric Times — Thu, 26 Jan 2012 12:00:00 +0100

Dr Roger McIntyre answers a reader's question. How would you answer? Take the quiz. (Source: Psychiatric Times)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Three cases of lithium exposure and exclusive breastfeeding

Archives of Women's Mental Health — Thu, 26 Jan 2012 06:56:56 +0100

Abstract The aim of this study was to provide data to aid decision making regarding lithium use during lactation. Three women treated with lithium for bipolar disorder during pregnancy and lactation and their four infants provided lithium levels at 1 month postpartum. Infant levels ranged from 10% to 17% of maternal levels. Two infants experienced early feeding problems which were overcome with breastfeeding education and support. Women taking lithium can be supported to breastfeed, and their infants should be followed closely until breastfeeding is well established. Content Type Journal ArticleCategory Short CommunicationPages 1-4DOI 10.1007/s00737-012-0257-3Authors Debra L. Bogen, Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh...

Reduced input from foot sole skin through cooling differentially modulates the short latency and medium latency vestibular reflex responses to galvanic vestibular stimulation.

Experimental Brain Research — Thu, 26 Jan 2012 05:00:00 +0100

Authors: Muise SB, Lam CK, Bent LR Abstract Sensory afferent information from the skin of the foot sole and information from the vestibular system converge within the central nervous system; however, their mode of interaction remains unknown. The purpose of this study was to investigate the effect of reduced cutaneous foot sole information on the ability of the vestibular system to evoke short latency (SL) and medium latency (ML) lower limb muscle reflex responses. Galvanic vestibular stimulation (GVS; bipolar; binaural; 25 ms; 2 mA square-wave pulse) was applied to standing human subjects (four women, eight men, average age 21.1 ± 3.0 years) both before and after cooling the foot soles in 1°C ice water (15 min initially, followed by 5 min between blocks of 200 GVS pulses)...

Reasons for substance use vary among mental health patients

MedWire News - Bipolar Disorder — Thu, 26 Jan 2012 00:00:00 +0100

The reasons for tobacco, alcohol, and cannabis use vary among patients with different mental health disorders, research shows. (Source: MedWire News - Bipolar Disorder)

Coupled Electrochemical Reactions at Bipolar Microelectrodes and Nanoelectrodes

Analytical Chemistry — Wed, 25 Jan 2012 20:01:23 +0100

Analytical ChemistryDOI: 10.1021/ac2028672 (Source: Analytical Chemistry)

Vascular function ‘not impaired’ in young BD patients

MedWire News - Bipolar Disorder — Wed, 25 Jan 2012 16:39:02 +0100

US researchers have found no evidence for impaired vascular function among relatively young patients with bipolar disorder. (Source: MedWire News - Bipolar Disorder)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Online Tissue Discrimination for Transcutaneous Needle Guidance Applications Using Broadband Impedance Spectroscopy

IEEE Transactions on Biomedical Engineering — Wed, 25 Jan 2012 14:46:09 +0100

This paper reports on a novel system architecture for measuring impedance spectra of a biological tissue close to the tip of a hollow needle. The measurement is performed online using fast broadband chirp signals. The time domain measurement raw data are transformed into the transfer function of the tissue in frequency domain. Correlation technique is used to analyze the characteristic shape of the derived tissue transfer function with respect to known “library functions” for different types of tissue derived in earlier experiments. Based on the resulting correlation coefficients the exact type of tissue is determined. A bipolar coaxial needle is constructed, simulated by finite element method and tested during various in vitro and in vivo experiments. The results show a good...

Depression Symptoms 3

About.com Bipolar Disorder — Wed, 25 Jan 2012 05:00:00 +0100

This article examines those symptoms and discusses how they are different from those of situational depression. (Source: About.com Bipolar Disorder)

Dissociable patterns of medial prefrontal and amygdala activity to face identity versus emotion in bipolar disorder.

Psychological Medicine — Wed, 25 Jan 2012 05:00:00 +0100

CONCLUSIONS: This is the first study to examine neural circuitry supporting face identity and face emotion processing in bipolar disorder. Our findings of abnormally elevated activity in amygdala and medial prefrontal cortex (mPFC) during face identity and happy face emotion processing suggest functional abnormalities in key regions previously implicated in social processing. This may be of future importance toward examining the abnormal self-related processing, grandiosity and social dysfunction seen in bipolar disorder. PMID: 22273442 [PubMed - as supplied by publisher] (Source: Psychological Medicine)

Antipsychotic Medicines Adherence and Satisfaction Among Palestine People with Schizophrenia.

Current Clinical Pharmacology — Wed, 25 Jan 2012 05:00:00 +0100

Conclusions: Medication nonadherence was common and was associated with low treatment satisfaction scores and poor psychiatric scores. Medication related factors had insignificant effects on adherence scores. PMID: 22283608 [PubMed - as supplied by publisher] (Source: Current Clinical Pharmacology)

Continuing Bipolar for Beginners: Causes of Bipolar Disorder

About.com Bipolar Disorder — Wed, 25 Jan 2012 05:00:00 +0100

Here's part 2 of Bipolar for Beginners, a series designed to walk you through the basic information about bipolar disorder. Lesson 1, Introducing Bipolar Disorder, started you out with the most basic information: an explanation of what bipolar is along with definitions of terms that are essential to understanding the illness. Lesson 1 also debunks some of the common myths. Lesson 2 covers what's known about the genetic component of mental disorders, theories regarding the relationship between stress and genetic susceptibility, and types of stresses that could bring on a bipolar episode. In addition, this lesson takes a look at the inner workings of nerves in the brain that are thought to affect moods. Finally, there's the story of a court decision legally confirming that bipolar disorder ...

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Seasonal variation in hospital admission rates for mood disorders

MedWire News - Bipolar Disorder — Wed, 25 Jan 2012 00:00:00 +0100

Results from a study conducted in Egypt show significant seasonal variation in hospital admissions for mood disorders, but not for schizophrenia. (Source: MedWire News - Bipolar Disorder)

A dicarbazole-triazine hybrid bipolar host material for highly efficient green phosphorescent OLEDs

RSC - J. Mater. Chem. latest articles — Tue, 24 Jan 2012 18:17:11 +0100

J. Mater. Chem., 2012, Advance ArticleDOI: 10.1039/C2JM14686J, PaperChih-Hao Chang, Ming-Cheng Kuo, Wei-Chieh Lin, Yu-Ting Chen, Ken-Tsung Wong, Shu-Hua Chou, Ejabul Mondal, Raymond C. Kwong, Sean Xia, Tetsuya Nakagawa, Chihaya AdachiA dicarbazole-triazine bipolar host CzT with promising physical properties was utilized to achieve highly efficient yellowish-green phosphorescent OLEDs.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Mater. Chem. latest articles)

Kinase Activity of Fission Yeast Mph1 Is Required for Mad2 and Mad3 to Stably Bind the Anaphase Promoting Complex.

Current Biology — Tue, 24 Jan 2012 05:00:00 +0100

Authors: Zich J, Sochaj AM, Syred HM, Milne L, Cook AG, Ohkura H, Rappsilber J, Hardwick KG Abstract Defects in chromosome segregation result in aneuploidy, which can lead to disease or cell death [1, 2]. The spindle checkpoint delays anaphase onset until all chromosomes are attached to spindle microtubules in a bipolar fashion [3, 4]. Mad2 is a key checkpoint component that undergoes conformational activation, catalyzed by a Mad1-Mad2 template enriched at unattached kinetochores [5]. Mad2 and Mad3 (BubR1) then bind and inhibit Cdc20 to form the mitotic checkpoint complex (MCC), which binds and inhibits the anaphase promoting complex (APC/C). Checkpoint kinases (Aurora, Bub1, and Mps1) are critical for checkpoint signaling, yet they have poorly defined roles and few substrates have...

Decertification Outcomes for Bipolar Disorder in an Inpatient Community Mental Health Treatment Center: Impact on Subsequent Service Use Over Two Years.

Community Mental Health Journal — Tue, 24 Jan 2012 05:00:00 +0100

This study investigated differences in usage of inpatient and outpatient mental health services over a 2-year period following the index hospitalization between 50 decertified and 48 certified subjects with bipolar manic or mixed episode from an inpatient mental health treatment center. The decertified group had higher number of rehospitalization over the 2-year period compared to certified group (mean = 2.26, SE = 0.41 vs. mean = 1.19, SE = 0.24; Wald χ (2) = 5.50, p = 0.02). Median time to first rehospitalization was 40 weeks in the certified and 17 weeks in the decertified group, but the difference in time to rehospitalization failed to achieve statistical significance (p = 0.18). History of prior hospitalization was associated with higher numbers of rehospita...

[Confused woman shortly after childbirth].

Tidsskrift for den Norske Laegeforening — Tue, 24 Jan 2012 05:00:00 +0100

Authors: Brauer H, Martinsen EW Abstract Shortly after the birth of her first child a young woman became confused and agitated and was finally involuntarily admitted to an acute psychiatric ward. In spite of appropriate treatment with narcoleptics, she deteriorated from day to day and the staff members were uncertain what to do. New information from her close family concerning previous depressive and hippomanic episodes pointed to probable bipolar disorder. The treatment of choice was electroconvulsive therapy (ECT). In Norway this treatment requires informed consent, which she was not able to give. After consideration and discussions she was finally given ECT as emergency treatment. This had an immediate effect, and after a few treatments she recovered. She was given lithium to pr...

MedWorm Sponsor Message: Find the best January Sales in the UK.

Early PCE exposure linked to increased bipolar disorder risk

MedWire News - Psychiatry — Tue, 24 Jan 2012 00:00:00 +0100

Prenatal and early childhood exposure to drinking water contaminated with tetrachloroethylene is associated with an increased risk for bipolar disorder in later life, results from a US study suggest. (Source: MedWire News - Psychiatry)

Social-Cognitive Bias and Depressive Symptoms in Outpatients with Bipolar Disorder

Advances in Pharmacological Sciences — Mon, 23 Jan 2012 18:36:31 +0100

This study compares the attribution of intentions (social-cognitive bias) in a group of 37 outpatients with bipolar disorder with 32 matched control subjects. Bipolar patients scored significantly higher in the Ambiguous Intentions Hostility Questionnaire, showing an angry and intentionality bias (P=.001, P=.02). Differences in blame scale and hostility bias did not reach statistical significance, but a trend was found (P=.06). Bipolar patients with depressive symptoms presented a higher score in the angry bias scale (P=.03) and aggressivity bias scale (P=.004). The global functioning (GAF) correlates significantly with intentionality (P=.005), angry (P=.027), and aggressivity (P=.020) biases. Bipolar patients show a social-cognitive bias that may play a role in their functional outcome. (...

Lithium For Bipolar Disorder - Pros And Cons Unclear

Health News from Medical News Today — Mon, 23 Jan 2012 18:00:00 +0100

The most effective long-term treatment for bipolar disorder is lithium. It offers protection against depression and mania and reduces the risk of suicide and short-term mortality. However, according to a study in The Lancet ,safety concerns have made the use of lithium controversial. The authors examined about 400 articles to research the possible adverse effects of lithium and found abnormalities in the thyroid and parathyroid in about 25% of patients who receive lithium therapy, compared with 3% and 0â�¢1% in the general population... (Source: Health News from Medical News Today)

Medtronic Announces 510(k) Clearance For The Aquamantys SBS 5.0 Sheathed Bipolar Sealer For Spine Surgery

Medical Design Online News — Mon, 23 Jan 2012 14:00:00 +0100

Medtronic, Inc. announced today that it has received 510(k) clearance from the Food and Drug Administration (FDA) for the Aquamantys SBS 5.0 Sheathed Bipolar Sealer, a new addition to the spine portfolio of the company's Advanced Energy business (Source: Medical Design Online News)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Borderline Personality: The Promiscuous Diagnosis

Psychology Today Personality Center — Sun, 22 Jan 2012 17:32:45 +0100

Promiscuous Borderline Personality hangs out with many other diagnoses.read more (Source: Psychology Today Personality Center)

Link Between PCE In Drinking Water And An Increased Risk Of Mental Illness

Health News from Medical News Today — Sun, 22 Jan 2012 08:00:00 +0100

PCE in drinking water linked to an increased risk of mental illness The solvent tetrachloroethylene (PCE) widely used in industry and to dry clean clothes is a neurotoxin known to cause mood changes, anxiety, and depression in people who work with it. To date the long-term effect of this chemical on children exposed to PCE has been less clear, although there is some evidence that children of people who work in the dry cleaning industry have an increased risk of schizophrenia... (Source: Health News from Medical News Today)

Lithium Toxicity

About.com Bipolar Disorder — Sun, 22 Jan 2012 05:00:00 +0100

The window between the therapeutic dose of lithium and the toxic dose is almost vanishingly small. Differences in physiology may mean that what's the proper dose for one person is toxic for another. If you or someone you care for is taking lithium for bipolar disorder, it's essential to know not just the symptoms of lithium intoxication, but also what circumstances are most likely to lead to it. Lithium poisoning is no joke. When it's properly and promptly treated, most people recover with no aftereffects. But if it's not treated, or if treatment is delayed too long, it can have permanent consequences or lead to death. Read this vital information on Lithium Toxicity. Photo: wonderferret / Flickr. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Learn more or jo...

Fats and factors: lipid profiles associate with personality factors and suicidal history in bipolar subjects. - Evans SJ, Prossin AR, Harrington GJ, Kamali M, Ellingrod VL, Burant CF, McInnis MG.

SafetyLit: All (Unduplicated) — Sat, 21 Jan 2012 12:05:52 +0100

Polyunsaturated fatty acids (PUFA) have shown efficacy in the treatment of bipolar disorder, however their specific role in treating the illness is unclear. Serum PUFA and dietary intakes of PUFA associate with suicidal behavior in epidemiological studies.... (Source: SafetyLit: All (Unduplicated))

Antidepressant use and risk for suicide attempts in bipolar disorder. - Goldberg JF.

SafetyLit: All (Unduplicated) — Sat, 21 Jan 2012 12:05:52 +0100

[Abstract unavailable] Language: Eng... (Source: SafetyLit: All (Unduplicated))

MedWorm Sponsor Message: Find the best January Sales in the UK.

Depression sometimes shifts to bipolar disorder

MayoClinic.com Full Feed — Sat, 21 Jan 2012 06:00:00 +0100

Depression begins in many different ways, and can shift to bipolar disorder. The circumstances and treatment change as well. (Source: MayoClinic.com Full Feed)

Endoscopic submucosal dissection for large laterally spreading tumors involving the ileocecal valve and terminal ileum.

World Journal of Gastroenterology : WJG — Sat, 21 Jan 2012 05:00:00 +0100

Authors: Kishimoto G, Saito Y, Takisawa H, Suzuki H, Sakamoto T, Nakajima T, Matsuda T Abstract Endoscopic submucosal dissection is a challenging technique that enables en-bloc resection for large colorectal tumors, as laterally spreading tumors, particularly difficult, if the ileocecal valve and terminal ileum is involved. Herein, we report on one of 4 cases. The procedures, using a bipolar needle knife (B-Knife) to reduce the perforation risk and carbon dioxide instead of conventional air insufflation for patient comfort, achieved curative resections without any complications. PMID: 22294834 [PubMed - in process] (Source: World Journal of Gastroenterology : WJG)

Syndromal and Subsyndromal Illness Status and Five-Year Morbidity Using Criteria of the International Society for Bipolar Disorders Compared to Alternative Criteria

Psychopathology — Fri, 20 Jan 2012 23:00:00 +0100

Psychopathology 2012;45:102–108 (DOI:10.1159/000329740) (Source: Psychopathology)

The Challenge of Children with Special Needs

Psych Central — Fri, 20 Jan 2012 14:35:58 +0100

Labels abound, some of them distasteful, some inaccurate, some just in vogue, others useful to understanding and planning. I am speaking about children who have substantial special needs. They may be diagnosed with complex disorders such as Autism, Asperger’s, Pervasive Developmental Disorders, Bipolar Disorder, Tourette’s, or Mental Retardation. All are challenging to identify reliably, and even more challenging to treat effectively. We can add the physical disabilities of blindness, deafness, and a multitude of serious medical disorders that strike children and significantly limit their ability to function. Each of these disorders has books, websites, and national organizations devoted to them. Parents often know more about the specific disorder than any individual professional ...

Bipolar Drug May Spur Weight Gain, Thyroid Problems: Review

MedicineNet Kids Health General — Fri, 20 Jan 2012 07:00:00 +0100

Title: Bipolar Drug May Spur Weight Gain, Thyroid Problems: ReviewCategory: Health NewsCreated: 1/19/2012 8:06:00 PMLast Editorial Review: 1/20/2012 (Source: MedicineNet Kids Health General)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Mental health breakthrough: Study links sleep problems to schizophrenia for the first time

NaturalNews.com — Fri, 20 Jan 2012 06:00:00 +0100

Getting quality sleep could be a vitally important piece for solving the puzzle of mental health. Previous studies have linked poor sleep to depression, bipolar disorder, anxiety and ADHD. Now for the first time, research also shows a strong link between schizophrenia... (Source: NaturalNews.com)

Bipolar Drug May Spur Weight Gain, Thyroid Problems: Review

Pharmacy News - Doctors Lounge — Fri, 20 Jan 2012 05:00:00 +0100

Overall, lithium still 'treatment of choice' but docs urged to watch for and manage side effects (Source: Pharmacy News - Doctors Lounge)

Occurrence of mental illness following prenatal and early childhood exposure to tetrachloroethylene (PCE)-contaminated drinking water: a retrospective cohort study

Environmental Health — Fri, 20 Jan 2012 05:00:00 +0100

Early-life exposure to PCE-contaminated drinking water may increase the risk of developing bipolar disorder and post-traumatic distress disorder later in life. (Source: Environmental Health)

Induction of ventricular tachycardia during radiofrequency ablation via pulmonary vein ablation catheter in a patient with an implanted pacemaker

Europace — Fri, 20 Jan 2012 05:00:00 +0100

Pulmonary vein isolation in a dual-chamber pacemaker patient using the pulmonary vein ablation catheter (PVAC) system resulted in perpetual induction of ventricular tachycardia (VT) during radio frequency energy application. Induction of VT was abolished by programming the PVAC-system to a pure bipolar ablation mode. Patients with implanted devices should be closely monitored when using the PVAC system in unipolar modes. (Source: Europace)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Bipolar Depression Symptoms - Emotional Pain

About.com Bipolar Disorder — Fri, 20 Jan 2012 05:00:00 +0100

Bipolar depression expresses itself in dozens of ways. One group of symptoms comes under the heading of emotional pain - the sadness, guilt feelings, helplessness and other feelings that contribute to the misery of depression. These symptoms aren't unique to bipolar depression or major depressive disorder by any means. Take a look at how this cluster of symptoms fits into the overall diagnosis of a bipolar depressive episode: Emotional Pain in Bipolar Depression. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Learn more or join the conversation! NEWSLETTER | FORUM | BIO | FACEBOOK | TWITTER . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .Bipolar Depression Symptoms - Emotional Pain originally appeared on About...

Bipolar Drug May Spur Weight Gain, Thyroid Problems

MedlinePlus Health News — Fri, 20 Jan 2012 00:00:00 +0100

Overall, lithium still 'treatment of choice' but docs urged to watch for and manage side effects Source: HealthDay Related MedlinePlus Pages: Bipolar Disorder, Medicines (Source: MedlinePlus Health News)

Vascular function ‘not impaired’ in young BD patients

MedWire News - Psychiatry — Fri, 20 Jan 2012 00:00:00 +0100

US researchers have found no evidence for impaired vascular function among relatively young patients with bipolar disorder. (Source: MedWire News - Psychiatry)

Panic Disorder in the Age of Anxiety

Psychology Today Anxiety Center — Thu, 19 Jan 2012 22:27:38 +0100

A recent New York Times op-ed argued that we are "well-medicated" in our anxiety. Is that actually true?read more (Source: Psychology Today Anxiety Center)

Differential neural activation patterns in children with BD and SMD

MedWire News - Psychiatry — Thu, 19 Jan 2012 14:51:03 +0100

Neural activation patterns differ between children with bipolar disorder and those with severe mood dysregulation during a motor inhibition task, researchers have found. (Source: MedWire News - Psychiatry)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

The Brown University Psychopharmacology Update — Thu, 19 Jan 2012 14:48:44 +0100

AbstractNo Increased Risk of Serious Cardiovascular Events with ADHD Drugs in Children or AdultsZolpidem Safe for Long‐Term Use in Physically and Mentally Healthy PatientsMirtazapine Reduces Methamphetamine Use and Sexual Risk Behavior in Men Who Have Sex with MenMaintenance Treatment of Bipolar I DisorderWhy Psychiatrists Should Treat SmokingIncreased Risks of Suicidal Behavior and Depression with Varenicline in Smoking CessationMortality in Antipsychotic‐Induced Neuroleptic Malignant SyndromeDelirium Following Addition of Adjunctive Quetiapine/Valproate in BPRecommendations Unchanged on ADHD DrugsSSRIs in Pregnancy: No Change in RecommendationsNew ApprovalsSafety Labeling Changes (Source: The Brown University Psychopharmacology Update)

PCE in drinking water linked to an increased risk of mental illness

EurekAlert! - Social and Behavioral Science — Thu, 19 Jan 2012 05:00:00 +0100

(BioMed Central) The solvent tetrachloroethylene widely used in industry and to dry clean clothes is a neurotoxin known to cause mood changes, anxiety, and depression in people who work with it. New research published in BioMed Central's open access journal Environmental Health found that exposure to PCE as a child was associated with an increased risk of bipolar disorder and post traumatic stress disorder. (Source: EurekAlert! - Social and Behavioral Science)

Increased Medial Orbitofrontal and Amygdala Activation: Evidence for a Systems-Level Endophenotype of Bipolar I Disorder.

The American Journal of Psychiatry — Thu, 19 Jan 2012 05:00:00 +0100

CONCLUSIONS: These results identify increased activity of the orbitofrontal cortex and the amygdala, related to heightened sensitivity to reward and deficient prediction error signal, as a candidate endophenotype of bipolar disorder. The results support a role of motivational processing in the risk architecture of bipolar disorder and identify a new systems-level therapeutic target for the illness. PMID: 22267184 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)

Differential neural activation patterns in children with BD and SMD

MedWire News - Bipolar Disorder — Thu, 19 Jan 2012 00:00:00 +0100

[Key points for the treatment of the elderly with bipolar disorder].

Tijdschrift voor Psychiatrie — Wed, 18 Jan 2012 19:18:02 +0100

Authors: Dols A, van Gerven H, Oostervink F, Schouws S, Tolner I, Kupka RW, Stek ML Abstract Summary background There is a lack of research into the treatment of the elderly with bipolar disorder. The Dutch guidelines for the treatment of older persons with bipolar disorder are based primarily on research relating to younger adults. aim To define key points for the treatment of bipolar disorder in later life. method The working group on the elderly of the Dutch Foundation for Bipolar Disorder defined key points in several consensus meetings based on clinical experience and research literature. <span class="subti...

MedWorm Sponsor Message: Find the best January Sales in the UK.

Bipolar blue-emitting poly(N-9[prime or minute]-heptadecanyl-carbazole-2,7-diyl-co-dibenzothiophene-S,S-dioxide-3,7-diyl)s

RSC - J. Mater. Chem. latest articles — Wed, 18 Jan 2012 18:44:06 +0100

J. Mater. Chem., 2012, Advance ArticleDOI: 10.1039/C2JM14926E, PaperRuifeng He, Sujun Hu, Jie Liu, Lei Yu, Bin Zhang, Na Li, Wei Yang, Hongbin Wu, Junbiao PengBipolar blue-emitting carbazole-co-dibenzothiophene-S,S-dioxide copolymers exhibit high device efficiency and stability based on a single-layer device.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - J. Mater. Chem. latest articles)

Op-Ed Contributor: My So-Called Bipolar Life

NYT Health — Wed, 18 Jan 2012 05:27:01 +0100

Claire Danes’s character in “Homeland” isn’t just like me. She is me. (Source: NYT Health)

Introducing Bipolar Disorder

About.com Eating Disorders — Wed, 18 Jan 2012 05:00:00 +0100

Are you newly diagnosed with bipolar disorder? Have you just found out someone you care about is bipolar? Do you want to understand more about manic depression? Start here to find the accurate and honest answers you want and need. (Source: About.com Eating Disorders)

Postpartum and Depression Status are Associated With Lower [11C]raclopride BPND in Reproductive-Age Women

Neuropsychopharmacology — Wed, 18 Jan 2012 05:00:00 +0100

Postpartum and Depression Status are Associated With Lower [11C]raclopride BPND in Reproductive-Age Women Neuropsychopharmacology advance online publication, January 18, 2012. doi:10.1038/npp.2011.328 Authors: Eydie L Moses-Kolko, Julie C Price, Katherine L Wisner, Barbara H Hanusa, Carolyn C Meltzer, Sarah L Berga, Anthony A Grace, Teresa Lanza di Scalea, Walter H Kaye, Carl Becker & Wayne C Drevets Keywords: depression; unipolar; bipolar; imaging; clinical or preclinical; dopamine; psychiatry & behavioral sciences; D2/3 receptors; postpartum depression; positron emission tomography; women (Source: Neuropsychopharmacology)

Is Tubal Ligation Reversal Possible With Burned Tubes?

Tubal Ligation Reversal News — Wed, 18 Jan 2012 00:00:00 +0100

One of the best ways to determine if tubal reversal surgery will be successful is with the operative report from the tubal ligation. These records can be obtained from the doctor who tied the tubes or from the hospital where the tubal ligation was performed. Patients send this information to Chapel Hill Tubal Reversal Center for a free interpretation by Dr. Gary Berger and Dr. Charles Monteith, the top rated specialists in reversing tied tubes. Bridget, a member of the Tubal Reversal Message Board, shares her birthday present - the good news that she obtained her operative report. "So happy! Today is my birthday and I've been waiting since mid December for my medical records to be sent to Chapel Hill and I got the email today. I had bipolar coagulation and with my age this gives me a 74% c...

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Limbic network disruption may characterize bipolar disorder

MedWire News - Psychiatry — Wed, 18 Jan 2012 00:00:00 +0100

Results from a Chinese study show that bipolar disorder patients have gray and white matter abnormalities that indicate disorganization of the limbic network. (Source: MedWire News - Psychiatry)

42 Percent of Online Consumers Think Pharma Companies Should be Involved in Online Health Communities

Drugs.com - Pharma News — Tue, 17 Jan 2012 15:37:51 +0100

– ADD/ADHD and Bipolar Disorder Caregivers Top Groups to Agree ePharma Consumer® Study Reveals New Trends around How Consumers Interact with Pharma, Including Customer Service Options, Patient Education, and Pharma Websites – Webinar... (Source: Drugs.com - Pharma News)

Review: some evidence of impaired neurocognitive performance in children and adolescents with bipolar disorder

Evidence-Based Mental Health — Tue, 17 Jan 2012 05:00:00 +0100

QuestionQuestion Do children and adolescents with bipolar disorder exhibit cognitive impairment and on which domains? MethodsDesign Systematic review. Data sources Pubmed and PsychINFO were searched from inception to February 2011 for studies examining cognitive impairments in children and adolescents with bipolar disorder. Reference lists of identified studies were hand searched. Study selection and analysis Reviewers selected studies comparing cognitive impairments in children and adolescents (aged less than 18 years old) with DSM-IV bipolar disorder with either a healthy sample or normative data. No meta-analyses were performed. Main results Twenty-one articles (19 cross-sectional, two longitudinal) met inclusion criteria. There were 757 participants with bipolar disorder (BD) (73% wi...

Mortality gap between people with schizophrenia or bipolar disorder and the general population persists in England

Evidence-Based Mental Health — Tue, 17 Jan 2012 05:00:00 +0100

QuestionQuestion Has the risk of mortality in people with schizophrenia or bipolar disorder remained elevated compared with the general population in recent years? Population All people with schizophrenia (n=272 248) and bipolar disorder (n=100 851) discharged after hospital inpatient care from 1999 to 2006. Setting Inpatient hospital episode statistics in England and death registration data from the Office of National Statistics; from 1999 to 2007. Prognostic factors Schizophrenia (international classification of diseases (ICD-10) or bipolar disorder (ICD-10) as the principal diagnosis on the hospital discharge record. Outcomes Mortality within 1 year of discharge from psychiatric inpatient care. Causes of death were determined from death certificates (ICD-10). Deaths were classified as u...

MedWorm Sponsor Message: Find the best January Sales in the UK.

Review: second-generation antipsychotics improve response in paediatric bipolar disorder, but are associated with adverse events

Evidence-Based Mental Health — Tue, 17 Jan 2012 05:00:00 +0100

QuestionQuestion What is the efficacy of antimanic pharmacotherapy for paediatric bipolar disorder? Outcomes Change in the Young Mania Rating Scale (YMRS) score; response as defined in the individual studies (typically defined as ≥50% decrease in YMRS score. MethodsDesign Systematic review and meta-analysis. Data sources PubMed was searched from 1989 to 2010. Additionally, the references of all recent review articles on paediatric bipolar disorder were reviewed manually. Study selection and analysis Open-label studies and double blind randomised controlled trials published in English were included. Chart reviews and case reports were excluded. Combination treatment studies were limited to acute randomised clinical trials of no more than two medicines. If a study evaluated more than one...

Lithium and valproate prevent olfactory discrimination and short-term memory impairments in the intranasal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) rat model of Parkinson's disease.

Behavioural Brain Research — Tue, 17 Jan 2012 05:00:00 +0100

Authors: Castro AA, Ghisoni K, Latini A, Quevedo J, Tasca CI, Prediger RD Abstract We have recently demonstrated that rodents treated intranasally with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) display time-dependent impairments in olfactory, emotional, cognitive and motor functions associated with disruption of dopaminergic neurotransmission in different brain structures conceivably analogous to those observed during different stages of Parkinson's disease (PD). On the other hand, lithium (Li) and valproate (VPA) are two primary drugs used to treat bipolar mood disorder that have recently emerged as promising neuroprotective agents. The present data indicates that the pretreatment with Li (47.5mg/kg) or VPA (200mg/kg) by intraperitoneal route during 7 consecutive days wa...

Lundbeck introduces new treatment for depressive disorder in UK

Drug Development Technology — Tue, 17 Jan 2012 00:00:00 +0100

Lundbeck, an international pharmaceutical company, has announced that Sycrest (asenapine) is being launched in the UK for treating moderate to severe manic episodes associated with bipolar I disorder in adults. (Source: Drug Development Technology)

BDNF not linked to executive function in BD patients

MedWire News - Psychiatry — Tue, 17 Jan 2012 00:00:00 +0100

Executive function is not associated with levels of brain-derived neurotrophic factor in patients with bipolar disorder, study results suggest. (Source: MedWire News - Psychiatry)

Functional impairments persist in remitted BD patients

MedWire News - Psychiatry — Mon, 16 Jan 2012 17:41:02 +0100

A significant proportion of bipolar disorder patients who receive specialized mental health care achieve symptomatic recovery, but functional recovery is much less common, study results show. (Source: MedWire News - Psychiatry)

New treatment launched in UK for bipolar

Pharmacy Europe — Mon, 16 Jan 2012 11:30:00 +0100

Sycrest® (asenapine) provides alternative, with 44% of patients unsatisfied with current treatment (Source: Pharmacy Europe)

New treatment launched in UK for bipolar disorder

Pharmacy Europe — Mon, 16 Jan 2012 11:30:00 +0100

Sycrest® (asenapine) provides an alternative for 44% of patients unsatisfied with current treatment (Source: Pharmacy Europe)

Bipolar Disorder - I'm Bipolar - a psychiatric biography - newly diagnosed

About.com Bipolar Disorder — Mon, 16 Jan 2012 05:00:00 +0100

A series of first-person articles beginning on the day the author was diagnosed as having Bipolar Disorder. Follow the trials, setbacks and triumphs as she goes through multiple medication and lifestyle changes. (Source: About.com Bipolar Disorder)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Bipolar disorder chat login page and schedule - support and information chats

About.com Bipolar Disorder — Mon, 16 Jan 2012 05:00:00 +0100

A meeting place to offer or receive support for coping with manic depression, or to share experiences and ask for information about this website's resources. (Source: About.com Bipolar Disorder)

Electroconvulsive Therapy

About.com Bipolar Disorder — Mon, 16 Jan 2012 05:00:00 +0100

Electroconvulsive therapy or ECT is a treatment in which a convulsion is produced by passing an electric current through the brain. More ... (Source: About.com Bipolar Disorder)

mGluR6 deletion renders the TRPM1 channel in retina inactive

Journal of Neurophysiology — Mon, 16 Jan 2012 05:00:00 +0100

In darkness, glutamate released from photoreceptors activates the metabotropic glutamate receptor 6 (mGluR6) on retinal ON bipolar cells. This activates the G protein Go, which then closes transient receptor potential melastatin 1 (TRPM1) channels, leading to cells' hyperpolarization. It has been generally assumed that deleting mGluR6 would render the cascade inactive and the ON bipolar cells constitutively depolarized. Here we show that the rod bipolar cells in mGluR6-null mice were hyperpolarized. The slope conductance of the current-voltage curves and the current noise were smaller than in wild type. Furthermore, while in wild-type rod bipolar cells, TRPM1 could be activated by local application of capsaicin; in null cells, it did not. These results suggest that the TRPM1 channel in mGl...

Education and employment levels among Jamaican patients newly diagnosed with schizophrenia and bipolar disorder.

The International Journal of Social Psychiatry — Mon, 16 Jan 2012 05:00:00 +0100

CONCLUSIONS: The low educational achievement among persons with schizophrenia makes education a potentially important area for interventions targeted at this group. Because gross deficiencies in job skills were common to both patient groups, improvement in job skill levels is an important goal for persons with either of these disorders. PMID: 22249465 [PubMed - as supplied by publisher] (Source: The International Journal of Social Psychiatry)

New Information Links Lithium to Thyroid, Parathyroid Problems

About.com Bipolar Disorder — Mon, 16 Jan 2012 05:00:00 +0100

A new review published today in The Lancet found that in addition to the known potential for causing weight gain, taking lithium may increase the activity of the thyroid and parathyroid glands. Because of the increased risk for hyperparathyroidism, it is now recommended that doctors check blood calcium levels, an indicator for parathyroid activity, before beginning lithium therapy and periodically while the patient is taking lithium. Lithium is a first-line treatment for bipolar disorder and may be used as add-on treatment for major depression. The review found that patients taking lithium gained more weight than those taking a placebo, but less than those taking Zyprexa (olanzapine). For more information: Lithium Drug Profile Hyperparathyroidism Hyperthyroidism Source: McKnight, R, ...

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Improvement of temperature-stability in a quantum well laser with asymmetric barrier layers

Applied Physics Letters — Mon, 16 Jan 2012 03:35:18 +0100

Alexey E. Zhukov, Natalia V. Kryzhanovskaya, Fedor I. Zubov, Yuri M. Shernyakov, Mikhail V. Maximov et al. We fabricated and tested a quantum well laser with asymmetric barrier layers. Such a laser has been proposed earlier to suppress bipolar carrier population in the optical confinement layer and thus to improve temperature-stability of the threshold current. As compared to the conventional reference l ... [Appl. Phys. Lett. 100, 021107 (2012)] published Tue Jan 10, 2012. (Source: Applied Physics Letters)

Introducing Bipolar for Beginners

About.com Bipolar Disorder — Sun, 15 Jan 2012 05:00:00 +0100

You might need this information in a compact form that guides you through the basic information about bipolar disorder because you're newly diagnosed. You might need it because someone in your family has been diagnosed, or you've just learned that a friend, someone you're dating, or someone you work with is bipolar. You might even be writing a term paper on bipolar disorder. No matter what the reason, you want to learn about BP from the ground up - so I've put together one page that will guide you through the first steps to knowledge. This will be a series of walk-through pages, and by the time you've gone through them all, you'll have a strong understanding of what bipolar disorder is, the symptoms, the moods, the complexities and more. Watch this blog for the next in the series! Get St...

Serum lipids, metabolic syndrome and lifetime suicide attempts in patients with bipolar disorder. - D'Ambrosio V, Salvi V, Bogetto F, Maina G.

SafetyLit: All (Unduplicated) — Sat, 14 Jan 2012 23:37:58 +0100

OBJECTIVE: Bipolar disorder is associated with a high risk of suicide. Many clinical characteristics and, recently, biomarkers have been studied with the aim to find useful predictors of suicidality. The role of serum lipids has also been explored albeit w... (Source: SafetyLit: All (Unduplicated))

Bipolar depression and suicidal behavior. - Guillaume S, Courtet P, Samalin L.

SafetyLit: All (Unduplicated) — Sat, 14 Jan 2012 23:37:58 +0100

Suicide is a frequent and tragic consequence of bipolar depression. The prevention of suicidal behavior (SB) need an assessment of vulnerability traits related related to SB (personal suicide history, impulsive traits…), characteristics of depression (mi... (Source: SafetyLit: All (Unduplicated))

Resolvin E1 Reduces Intraabdominal Adhesions by Inhibiting Macrophage Chemoattraction into the Peritoneum

Journal of Surgical Research — Sat, 14 Jan 2012 22:29:49 +0100

Introduction: Postoperative adhesions occur in more than 94% of patients after abdominopelvic surgery and can lead to serious complications including small bowel obstruction and infertility. We have previously demonstrated that a robust inflammatory response ensues within hours of abdominal surgery and that elevated levels of the proinflammatory mediators such as the neutrophil chemoattractant CXCL1 and CXCL2 and their receptor CXCR2 underlie this response. Macrophage chemoattractant CCL1 and its receptor CCR8 are also implicated in adhesion formation. the early recruitment of these inflammatory cells is thought to contribute to the suppression of peritoneal fibrinolytic activity and initiate adhesiogenesis. Resolvin E1 (RvE1) is a potent proresolving lipid mediator of inflammation derived...

MedWorm Sponsor Message: Find the best January Sales in the UK.

Baffling Study on Immigration and Psychosis

About.com Bipolar Disorder — Fri, 13 Jan 2012 13:37:59 +0100

In the December issue of the American Journal of Psychiatry is a report on a Dutch study regarding age of immigration and risk of future psychosis that has me scratching my head. After gathering data for 7 years on immigrants who "made a first contact with a physician for a suspected psychotic disorder," the researchers looked at the age when those people migrated to the Netherlands. According to an article in the New York Times, they found that those who came from Suriname, the Netherlands Antilles, Turkey and Morocco, and who immigrated as infants and up to the age of four, had the highest incidence of psychosis in later life, Baffling Study on Immigration and Psychosis originally appeared on About.com Bipolar Disorder on Friday, January 13th, 2012 at 13:37:59.Permalink | Comment | Emai...

ARFI‐prepared MRgHIFU in liver: Simultaneous mapping of ARFI‐displacement and temperature elevation, using a fast GRE‐EPI sequence

Magnetic Resonance in Medicine — Fri, 13 Jan 2012 05:00:00 +0100

AbstractMR acoustic radiation force imaging (ARFI) is an elegant adjunct to MR‐guided high intensity focused ultrasound for treatment planning and optimization, permitting in situ assessment of the focusing and targeting quality. The thermal effect of high intensity focused ultrasound pulses associated with ARFI measurements is recommended to be monitored on line, in particular when the beam crosses highly absorbent structures or interfaces (e.g., bones or air‐filled cavities). A dedicated MR sequence is proposed here, derived from a segmented gradient echo‐echo planar imaging kernel by adding a bipolar motion encoding gradient with interleaved alternating polarities. Temporal resolution was reduced to 2.1 s, with in‐plane spatial resolution of 1 mm. MR‐ARFI measurements were exe...

Are You So Used to Depression That You Can't See It?

About.com Bipolar Disorder — Fri, 13 Jan 2012 05:00:00 +0100

When a friend of mine suggested maybe I was "conditioned to depression," it was a revelation to me. This is not using "conditioned" in the formal psychological sense, mind you. It's more like being annoyed at having to put a heavy coat on when the weather first gets cold, but after awhile, you don't think about it any more. You're used to doing it. In a similar way, the habits of depression can become so much a part of your life that you become used to them. When you're moving from a stable mood - particular if it's a low-level stable mood as can occur in Bipolar II - into the first stages of a depressed mood, you don't recognize that something is changing, because that state and the habits that go with it are so familiar that you're conditioned to them. See if you recognize yourself: Ar...

ARFI-prepared MRgHIFU in liver: Simultaneous mapping of ARFI-displacement and temperature elevation, using a fast GRE-EPI sequence.

Magnetic Resonance in Medicine — Fri, 13 Jan 2012 05:00:00 +0100

Authors: Auboiroux V, Viallon M, Roland J, Hyacinthe JN, Petrusca L, Morel DR, Goget T, Terraz S, Gross P, Becker CD, Salomir R Abstract MR acoustic radiation force imaging (ARFI) is an elegant adjunct to MR-guided high intensity focused ultrasound for treatment planning and optimization, permitting in situ assessment of the focusing and targeting quality. The thermal effect of high intensity focused ultrasound pulses associated with ARFI measurements is recommended to be monitored on line, in particular when the beam crosses highly absorbent structures or interfaces (e.g., bones or air-filled cavities). A dedicated MR sequence is proposed here, derived from a segmented gradient echo-echo planar imaging kernel by adding a bipolar motion encoding gradient with interleaved alternatin...

Science News » Atypical antipsychotic more effective than older drugs in treating childhood mania, but side effects can be serious

National Institute of Mental Health — Thu, 12 Jan 2012 13:39:49 +0100

The antipsychotic medication risperidone is more effective for initial treatment of mania in children diagnosed with bipolar disorder compared to other mood stabilizing medications, but it carries the potential for serious metabolic side effects, according to an NIMH-funded study published online ahead of print January 2, 2012, in the Archives of General Psychiatry. (Source: National Institute of Mental Health)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Metabolic syndrome common in Indian bipolar disorder patients

MedWire News - Bipolar Disorder — Thu, 12 Jan 2012 13:39:05 +0100

Results from an Indian study suggest that the metabolic syndrome is highly prevalent among patients with bipolar disorder, with abdominal obesity being the most common component. (Source: MedWire News - Bipolar Disorder)

Asymmetry of Polarization Reversal and Current-Voltage Characteristics of Pt/PZT-Film/Pt:Ti/SiO2/Si-Substrate Structures

Computational Intelligence and Neuroscience — Thu, 12 Jan 2012 11:11:41 +0100

The characterization of the asymmetries of bipolar charge-voltage and current-voltage loops of polarization reversal and unipolar current-voltage curves for Pt/PZT-film/Pt:Ti/SiO2/Si-substrate systems was performed in the dynamic mode. The asymmetry of local deformation-voltage loops was observed by piezoresponse force microscopy. The comparison of the dependences of introduced asymmetry factors for the bipolar charge-voltage and current-voltage loops and unipolar current-voltage curves on drive voltage indicates the interconnection of ferroelectric and electrical space charge transfer asymmetries. (Source: Computational Intelligence and Neuroscience)

On the Medication Carousel

About.com Bipolar Disorder — Thu, 12 Jan 2012 05:00:00 +0100

In Part 11 of this series the bipolar patient is still depressed and medication changes are frequent. Wellbutrin - Celexa - Trazodone - Zyprexa - gosh it's a poem! (Source: About.com Bipolar Disorder)

Medication Primer

About.com Mental Health — Thu, 12 Jan 2012 05:00:00 +0100

Mental health medications are used to treat a number of mental disorders. Read about schizophrenia medications, antidepressants, bipolar medications, and anxiety medications. (Source: About.com Mental Health)

MedWorm: Bipolar

Melatonin receptors are anatomically organized to modulate transmission specifically to cone pathways in the retina of Xenopus laevis

Abortion doesn't up risk of mental illness relapse

Positive Topline Phase 3 Results for Acute Mania DrugPositive Topline Phase 3 Results for Acute Mania Drug

Organizational motifs for ground squirrel cone bipolar cells

Temperaments linked to clinical features and course in bipolar I disorder

Chinese version of MDQ effective for BD screening

Customized adherence enhancement for individuals with bipolar disorder receiving antipsychotic therapy

The Gentle Self: How to Overcome Your Difficulties with Depression, Anxiety, Shyness, and Low Self-Esteem

Solution-processable small molecules as efficient universal bipolar host for blue, green and red phosphorescent inverted OLEDs

Differentiating between Bipolar Disorder Types I and II: Results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). - Bega S, Schaffer A, Goldstein B, Levitt A.

Age at onset versus family history and clinical outcomes in 1,665 international bipolar-I disorder patients. - Baldessarini RJ, Tondo L, Vazquez GH, Undurraga J, Bolzani L, Yildiz A, Khalsa HM, Lai M, Lepri B, Lolich M, Maffei PM, Salvatore P, Faedda GL, Vieta E, Mauricio T.

Highly Sensitive to Noise?

Influence of Patient Race and Ethnicity on Clinical Assessment in Patients With Affective Disorders [Original Article]

Differences in the Circuitry-Based Association of Copy Numbers and Gene Expression Between the Hippocampi of Patients With Schizophrenia and the Hippocampi of Patients With Bipolar Disorder [Original Article]

Subcallosal Cingulate Deep Brain Stimulation for Treatment-Resistant Unipolar and Bipolar Depression [Original Article]

What Is Schizoaffective Disorder?

Hospitalization for psychiatric disorders before and after onset of unprovoked seizures/epilepsy

Chinese version of MDQ effective for BD screening

What Are the Causes of Bipolar Disorder?

Erratum: Conversion from unipolar to bipolar resistance switching by inserting TaO layer in Pt/TaO/Pt cells [Appl. Phys. Lett. 98, 183507 (2011)]

Separation of Electrical and Optical Energy Gaps for Constructing Bipolar Organic Wide Bandgap Materials

Who Is Left Out of the DSM-5 Debate? Of Course, Consumers

Metabolic Side Effects Such As Obesity And Diabetes Caused By Antipsychotic Medications

[Original Articles] Fertility Treatment Response: Is It Better to Be More Optimistic or Less Pessimistic?

Radio Frequency Ablation vs. Bipolar Umbilical Cord Coagulation in the Management of Complex Monochorionic Pregnancies

Radio Frequency Ablation vs. Bipolar Umbilical Cord Coagulation in the Management of Complex Monochorionic Pregnancies.

Nitrous oxide: Manic relapse: case report

Recovery of visual function in patient with melanoma-associated retinopathy treated with surgical resection and interferon-beta

Circulating concentrations, cerebral output of the CINC-1 and blood–brain barrier disruption in Wistar rats after pneumococcal meningitis induction

New Study May End 2 Decades Of Suspicion: Does Borna Disease Virus Cause Mental Illness?

Radiofrequency volumetric tissue reduction of the inferior turbinate in a sheep model

Loss of Function of the Cik1/Kar3 Motor Complex Results in Chromosomes with Syntelic Attachment That Are Sensed by the Tension Checkpoint

Psychotherapy benefits youth with first-episode psychotic mania

Psychosocial functioning reduced in multiple-episode BD patients

Seizure risk increased before and after psychiatric hospitalization

Simultaneous Population Pharmacokinetic Modeling of Ketamine and Three Major Metabolites in Patients with Treatment‐Resistant Bipolar Depression

Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study

Pseudocholinesterase activity in type 1 bipolar patients.

Mapping vulnerability to bipolar disorder: a systematic review and meta-analysis of neuroimaging studies.

Systematic review of the neural basis of social cognition in patients with mood disorders.

Age at onset versus family history and clinical outcomes in 1,665 international bipolar-I disorder patients.

Biopsychosocial Model of Hypersexuality in Adolescent Girls With Bipolar Disorder: Strategies for Intervention

Cardiac Pacemakers in Electric and Magnetic Fields of 400‐kV Power Lines

Psychosocial functioning reduced in multiple-episode BD patients

Transformation kinetics of an intrinsic bistable defect in damaged silicon

Does Borna disease virus cause mental illness?

Cooling of the epileptic focus suppresses seizures with minimal influence on neurologic functions

Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder

Validation of the Chinese version of the "Mood Disorder Questionnaire" for screening bipolar disorder among patients with a current depressive episode

Lithium Toxicity - Types, Causes and Treatment

Short‐term electrical stimulation of the lower esophageal sphincter increases sphincter pressure in patients with gastroesophageal reflux disease

Nonepisodic factors may help differentiate BD subtypes

Poll: What Does the Evidence Say About Bipolar Disorder and Obesity?

New‐Onset Treatment‐Dependent Diabetes Mellitus and Hyperlipidemia Associated with Atypical Antipsychotic Use in Older Adults without Schizophrenia or Bipolar Disorder

One‐year psychosocial functioning in patients in the early vs. late stage of bipolar disorder

Effectiveness of a bipolar vessel sealant device for sealing uterine horns and bodies from dogs.

Change Proposed for Definition and Diagnosing of Cyclothymia

Cloning scientists create human brain cells

Table of Contents

Reintegration Awards Recognize Battle Against Schizophrenia and Bipolar Disorder

Messengers of the Brain

Antidepressant Treatment for Acute Bipolar Depression: An Update

Clinical and safety profiles of bipolar transurethral vaporization of the prostate in saline: A preliminary report

An Unusual Presentation of Primary Hyperparathyroidism: Pathological Fracture

Obesity and Bipolar Disorder

Three cases of lithium exposure and exclusive breastfeeding

Reduced input from foot sole skin through cooling differentially modulates the short latency and medium latency vestibular reflex responses to galvanic vestibular stimulation.

Reasons for substance use vary among mental health patients

Coupled Electrochemical Reactions at Bipolar Microelectrodes and Nanoelectrodes

Vascular function ‘not impaired’ in young BD patients

Online Tissue Discrimination for Transcutaneous Needle Guidance Applications Using Broadband Impedance Spectroscopy

Depression Symptoms 3

Dissociable patterns of medial prefrontal and amygdala activity to face identity versus emotion in bipolar disorder.

Antipsychotic Medicines Adherence and Satisfaction Among Palestine People with Schizophrenia.

Continuing Bipolar for Beginners: Causes of Bipolar Disorder

Seasonal variation in hospital admission rates for mood disorders

A dicarbazole-triazine hybrid bipolar host material for highly efficient green phosphorescent OLEDs

Kinase Activity of Fission Yeast Mph1 Is Required for Mad2 and Mad3 to Stably Bind the Anaphase Promoting Complex.

Decertification Outcomes for Bipolar Disorder in an Inpatient Community Mental Health Treatment Center: Impact on Subsequent Service Use Over Two Years.