MedWorm: Coeliac Disease

Mayo Clinic Study Finds Celiac Disease Four Times More Common than in 1950s

Mayo Clinic Research News — Wed, 01 Jul 2009 15:12:55 +0100

Celiac disease, an immune system reaction to gluten in the diet, is over four times more common today than it was 50 years ago, according to findings of a Mayo Clinic study published this month in the journal Gastroenterology. (Source: Mayo Clinic Research News)

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Mayo Clinic Study Finds Celiac Disease Four Times More Common than in 1950s

Mayo Clinic Rochester News — Wed, 01 Jul 2009 15:12:55 +0100

Celiac Disease Four Times More Common Than In 1950s

GastroIntestinal News From Medical News Today — Wed, 01 Jul 2009 12:00:00 +0100

Celiac disease four times more common than in '50s

CTV Health — Wed, 01 Jul 2009 11:40:29 +0100

Celiac disease, when gluten in the diet attacks the lining of the stomach, is four times more common than it was in the 1950s, according to new research, which also found a link between having undiagnosed celiac disease and a higher risk of death. (Source: CTV Health)

Celiac disease is on the rise

Scientific American - Official RSS Feed — Wed, 01 Jul 2009 06:00:00 +0100

Frozen blood samples collected more than 50 years ago reveal that celiac disease, an intolerance to the wheat protein gluten, was less than a quarter as common as it is today. [More] (Source: Scientific American - Official RSS Feed)

Mayo Clinic study finds celiac disease 4 times more common than in 1950s

EurekAlert! - Medicine and Health — Wed, 01 Jul 2009 04:00:00 +0100

(Mayo Clinic) Celiac disease, an immune system reaction to gluten in the diet, is over four times more common today than it was 50 years ago, according to findings of a Mayo Clinic study published this month in the journal Gastroenterology. (Source: EurekAlert! - Medicine and Health)

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Predictors of long-term survival after resection of esophageal carcinoma with nonregional nodal metastases.

The Annals of Thoracic Surgery — Tue, 30 Jun 2009 23:00:00 +0100

CONCLUSIONS: Surgical resection for patients with esophageal cancer associated with nonregional nodal metastases results in 25% survival at five years. Squamous histology, earlier T status, and perioperative chemotherapy are independent positive predictors of long-term survival. PMID: 19559222 [PubMed - in process] (Source: The Annals of Thoracic Surgery)

Recurrent mouth ulcers suggest celiac disease

Reuters: Health — Tue, 30 Jun 2009 18:06:06 +0100

NEW YORK (Reuters Health) - A minority of patients with recurrent mouth sores (aphthous stomatitis) have gluten-sensitive enteropathy, making evaluation for celiac disease appropriate in this population, according to a new study in BMC Gastroenterology. (Source: Reuters: Health)

Some Patients With Recurrent Aphthous Stomatitis Have Gluten-Sensitive Enteropathy

Medscape Today Headlines — Tue, 30 Jun 2009 15:56:40 +0100

A minority of patients with recurrent aphthous stomatitis (RAS) have gluten-sensitive enteropathy (GSE), and evaluation for celiac disease is appropriate in this population. Reuters Health Information (Source: Medscape Today Headlines)

[LETTERS TO THE EDITOR] Low Cholesterol and Mental Disorders in Children and Adolescents With Celiac Disease

Psychosomatics — Mon, 29 Jun 2009 23:00:00 +0100

(Source: Psychosomatics)

Recurrent month ulcers suggest celiac disease

Reuters: Health — Mon, 29 Jun 2009 22:20:51 +0100

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Recurrent Mouth Ulcers Suggest Celiac Disease

MedlinePlus Health News — Mon, 29 Jun 2009 21:20:51 +0100

A minority of patients with recurrent mouth sores (aphthous stomatitis) have gluten-sensitive enteropathy, making evaluation for celiac disease appropriate in this population, according to a new study in BMC Gastroenterology. Source: Reuters Health Related MedlinePlus Topics: Celiac Disease, Mouth Disorders (Source: MedlinePlus Health News)

Intestinal barrier function: Molecular regulation and disease pathogenesis

Journal of Allergy and Clinical Immunology — Mon, 29 Jun 2009 14:55:23 +0100

The intestinal epithelium is a single-cell layer that constitutes the largest and most important barrier against the external environment. It acts as a selectively permeable barrier, permitting the absorption of nutrients, electrolytes, and water while maintaining an effective defense against intraluminal toxins, antigens, and enteric flora. The epithelium maintains its selective barrier function through the formation of complex protein-protein networks that mechanically link adjacent cells and seal the intercellular space. The protein networks connecting epithelial cells form 3 adhesive complexes: desmosomes, adherens junctions, and tight junctions. These complexes consist of transmembrane proteins that interact extracellularly with adjacent cells and intracellularly with adaptor proteins...

Increasing prevalence and high incidence of celiac disease in elderly people: A population-based study

BMC Gastroenterology — Sun, 28 Jun 2009 23:00:00 +0100

Conclusions: The prevalence of celiac disease was high in elderly people, but the symptoms were subtle. Repeated screening detected five biopsy-proven cases in three years, indicating that the disorder may develop even in the elderly. Increased alertness to the disorder is therefore warranted. (Source: BMC Gastroenterology)

[ORIGINAL ARTICLES: GENERAL THORACIC] Predictors of Long-Term Survival After Resection of Esophageal Carcinoma With Nonregional Nodal Metastases

The Annals of Thoracic Surgery — Sun, 28 Jun 2009 23:00:00 +0100

Conclusions Surgical resection for patients with esophageal cancer associated with nonregional nodal metastases results in 25% survival at five years. Squamous histology, earlier T status, and perioperative chemotherapy are independent positive predictors of long-term survival. (Source: The Annals of Thoracic Surgery)

Stent implantation in chronic mesenteric ischemia.

Acta Radiologica — Sat, 27 Jun 2009 22:46:33 +0100

CONCLUSION: Our experience suggests that stent placement has a potential role in chronic mesenteric ischemia with low incidence of complications and high technical and clinical success rates. PMID: 19488893 [PubMed - in process] (Source: Acta Radiologica)

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Detection of lymph node metastases with ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance imaging in oesophageal cancer: a feasibility study.

Cancer Imaging — Sat, 27 Jun 2009 22:04:02 +0100

CONCLUSION: MRI+USPIO identified the majority of mediastinal and celiac (suspect) lymph nodes in 9 patients with oesophageal cancer. MRI+USPIO could have an additional value in loco-regional staging; however, more supplementary research is needed. PMID: 19414293 [PubMed - in process] (Source: Cancer Imaging)

Antibodies Against Deamidated Gliadin as New and Accurate Biomarkers of Childhood Coeliac Disease.

Journal of Pediatric Gastroenterology and Nutrition — Fri, 26 Jun 2009 14:21:41 +0100

Page: 52DOI: 10.1097/MPG.0b013e318195dae3Authors: Prause, Christian *; Ritter, Maria *; Probst, Christian +; Daehnrich, Cornelia +; Schlumberger, Wolfgang +; Komorowski, Lars +; Lieske, Ruediger ++; Richter, Thomas [S]; Hauer, Almuthe C ||; Stern, Martin [P]; Uhlig, Holm H #; Laass, Martin W **; Zimmer, Klaus-Peter ++; Mothes, Thomas * (Source: Journal of Pediatric Gastroenterology and Nutrition)

Acute Pancreatitis in a Child With Celiac Disease.

Journal of Pediatric Gastroenterology and Nutrition — Fri, 26 Jun 2009 14:21:41 +0100

Page: 137DOI: 10.1097/MPG.0b013e318172aad1Authors: Bultron, G *; Latif, U +; Park, A *; Phatak, U *; Pashankar, D *; Husain, SZ * (Source: Journal of Pediatric Gastroenterology and Nutrition)

Chromosome Instability in Lymphocytes of Children With Coeliac Disease.

Journal of Pediatric Gastroenterology and Nutrition — Fri, 26 Jun 2009 14:21:41 +0100

Page: 143DOI: 10.1097/MPG.0b013e31818c5294Authors: Martin-Arruti, Maialen *; Irastorza, Inaki +; de Prado, Elena *; Martin-Sanchez, Esperanza *; Martin-Guerrero, Idoia *; Ballesteros, Javier ++; Vitoria, Juan Carlos +,[S]; Garcia-Orad, Africa * (Source: Journal of Pediatric Gastroenterology and Nutrition)

An unusual cause of diarrhea: diffuse intestinal nodular lymphoid hyperplasia in association with selective immunoglobulin A deficiency (with video)

Gastrointestinal Endoscopy — Fri, 26 Jun 2009 14:20:40 +0100

A 33-year-old man was referred to our institution with a 5-year history of abdominal pain and diarrhea and recent weight loss. There was no history of recurrent sinopulmonary infection. A maternal history of celiac disease was reported Laboratory test results were normal except for a deficiency of serum immunoglobulin (Ig) A ( (Source: Gastrointestinal Endoscopy)

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Gluten encephalopathy with psychiatric onset: case report

Clinical Practice and Epidemiology in Mental Healt — Thu, 25 Jun 2009 23:00:00 +0100

Many cases of coeliac disease, a gastrointestinal autoimmune disorder caused by sensitivity to gluten, can remain in a subclinical stage or undiagnosed. In a significant proportion of cases (10-15%) gluten intolerance can be associated with central or peripheral nervous system and psychiatric disorders.A 38-year-old man was admitted as to our department an inpatient for worsening anxiety symptoms and behavioural alterations. After the addition of second generation antipsychotic to the therapeutic regimen, the patient presented neuromotor impairment with high fever, sopor, leukocytosis, raised rhabdomyolysis-related indicators. Neuroleptic malignant syndrome was strongly suspected. After worsening of his neuropsychiatric conditions, with the onset of a frontal cognitive deficit, bradykinesi...

Recent Advances in Coeliac Disease

Medscape Gastroenterology Headlines — Thu, 25 Jun 2009 18:13:32 +0100

Despite the encouraging progress that has taken place in our genetic and immunological knowledge of coeliac disease, early introduction of a gluten-free diet remains the cornerstone of treatment. Current Opinion in Gastroenterology (Source: Medscape Gastroenterology Headlines)

Meta-analysis - yield of diagnostic tests for coeliac disease in dyspepsia

Gastroenterology and Liver Diseases Specialist Library - Diagnostic procedures — Thu, 25 Jun 2009 16:10:08 +0100

Published July 2009.Bottom-line conclusion: The prevalence of biopsy-proven coeliac disease (CD) in subjects with dyspepsia was 1% and was higher than in controls, although this difference was not statistically significant. (Source: Gastroenterology and Liver Diseases Specialist Library - Diagnostic procedures)

Seropositivity for celiac disease in children and adolescents with short stature

Revista Paulista de Pediatria — Thu, 25 Jun 2009 08:09:23 +0100

CONCLUSIONS: The presence of serological marker of celiac disease in children and adolescents with low stature of low-income families highlights the need for systematic investigation of celiac disease in these patients. (Source: Revista Paulista de Pediatria)

Food That Makes You Different: The Stigma Experienced by Adolescents With Celiac Disease

Qualitative Health Research — Wed, 24 Jun 2009 23:00:00 +0100

For adolescents with celiac disease (CD), a gluten-free diet (GFD) is crucial for health, but compliance is problematic and noncompliance is common even among those aware of the risks. To better understand their lives with the disease, Swedish CD adolescents were invited to take part in focus group discussions. Data were analyzed for recurrent stigma-related themes across the groups. Adolescents described an awareness of being different from others that was produced by meal appearance and the poor availability of gluten-free food. The GFD often required discussions and special requests, so eating in public had the effect of making an invisible condition visible, and thereby creating a context for felt or enacted stigma. Maintaining invisibility avoided negative consequences of stigma, and ...

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Interventional EUS for the treatment of pancreatic cancer

Journal of Hepato-Biliary-Pancreatic Surgery — Tue, 23 Jun 2009 06:07:39 +0100

Abstract Since the curved linear array echoendoscope (linear EUS) was developed in the 1990s, EUS has evolved from EUS imaging, to EUS-guided FNA, and now to EUS-guided fine needle injection (FNI), giving EUS even wider application. This advancement has brought “interventional EUS” into the pancreato-biliary field. Interventional EUS for pancreatic cancer includes delivery of contrast agents, drainage/anastomosis, celiac neurolysis (including ganglion neorolysis), radiofrequency ablation, photodynamic therapy, brachytherapy, and delivery of a growing number of anti-tumor agents. This review will focus on interventional EUS in the treatment of pancreatic cancer. Content Type Journal ArticleCategory TopicsDOI 10.1007/s00534-009-0129-zAuthors Reiko Ashida, Irvine Medi...

Chronic mucocutaneous candidiasis may cause elevated gliadin antibodies

Acta Paediatrica — Sun, 21 Jun 2009 23:00:00 +0100

Conclusion: The common symptoms growth retardation, anaemia and elevated gliadin antibodies are suggestive for celiac disease but very unspecific. The rare immunodeficiency CMC may cause elevated gliadin antibodies. (Source: Acta Paediatrica)

Familial association between type 1 diabetes and other autoimmune and related diseases

Diabetologia — Sat, 20 Jun 2009 05:59:53 +0100

Conclusions/interpretation The concordant familial risks for type 1 diabetes were high and the calculated risk for multiplex families and monozygotic twins may be explained by epistatic gene × gene or gene × environment interactions. Familial associations with several autoimmune and related diseases suggest genetic sharing and challenge to gene identification. Content Type Journal ArticleCategory ArticleDOI 10.1007/s00125-009-1427-3Authors K. Hemminki, German Cancer Research Center (DKFZ) Division of Molecular Genetic Epidemiology Im Neuenheimer Feld 580 69120 Heidelberg GermanyX. Li, Lund University Center for Primary Health Care Research Malmö SwedenJ. Sundquist, Lund University Center for Primary Health Care Research Malmö SwedenK. Sundquist, Karolinska...

Impact of integrated PET/CT in the staging of oesophageal cancer—a UK population-based cohort study

Clinical Radiology — Wed, 17 Jun 2009 08:13:21 +0100

Conclusion: This study confirms the role of PET/CT in a multicentre UK setting in the management of patients with potentially curable carcinoma of the oesophagus, improving the accuracy of pre-treatment staging compared with CT and EUS alone. Early tumours infrequently show evidence of metastasis on PET/CT, although further data are required to confidently determine the stage of tumours where PET/CT has no additional value. (Source: Clinical Radiology)

Celiac Disease-Related Antibodies in Italian Children With Epilepsy

Pediatric Neurology — Wed, 17 Jun 2009 03:33:09 +0100

In this study, 272 Italian children with epilepsy and 300 healthy children were screened for anti-gliadin and anti-transglutaminase immunoglobulin A and G; positive and borderline samples were tested for the presence of anti-endomysium antibodies. The prevalence of antibodies related to celiac disease was comparable to that of healthy controls. In keeping with this observation, Italian epileptic children should not be considered a group at risk for celiac disease. (Source: Pediatric Neurology)

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Gluten sensitivity enteropathy in patients with recurrent aphthous stomatitis

BMC Gastroenterology — Tue, 16 Jun 2009 23:00:00 +0100

Conclusions: A significant minority (e.g. 2.83%) of RAS patients have GSE. This could be compared with the 0.96% prevalence of GSE in the general population of Iran. This study suggests that evaluation for celiac disease is appropriate in patients with RAS. Additionally, the unresponsiveness to conventional anti-aphthae treatment could be an additional risk indicator. (Source: BMC Gastroenterology)

Clinical features of chronic C virus hepatitis in patients with celiac disease

European Journal of Clinical Microbiology & Infectious Diseases — Tue, 16 Jun 2009 05:50:31 +0100

Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s10096-009-0769-6Authors M. Silano, Istituto Superiore di Sanità Division of Food Science, Human Nutrition and Health Viale Regina Elena 299 Roma 00161 ItalyU. Volta, S. Orsola-Malpighi Hospital Department of Internal Medicine Bologna ItalyO. Vincentini, Istituto Superiore di Sanità Division of Food Science, Human Nutrition and Health Viale Regina Elena 299 Roma 00161 ItalyM. De Vincenzi, Istituto Superiore di Sanità Division of Food Science, Human Nutrition and Health Viale Regina Elena 299 Roma 00161 ItalyFor the Italian Registry of the Complications of Celiac Disease, Istituto Superiore di Sanità Division of Food Science, Human Nutrition and Health Viale Regina Elena 299 Roma 00161 Italy Journal European Journal...

Going Gluten-Free At Age 13

NPR Health and Science — Mon, 15 Jun 2009 04:01:00 +0100

Jacob Rosenblum has celiac disease, an autoimmune condition that keeps his body from processing foods with wheat gluten. Even though he can't eat his peanut butter and jelly sandwiches on wheat bread anymore, or most cereals, his family is finding new ways to cook gluten-free and keep him healthy.» E-Mail This » Add to Del.icio.us (Source: NPR Health and Science)

Multiple sclerosis association study with the TENR-IL2-IL21 region in a Spanish population

Tissue Antigens — Sun, 14 Jun 2009 04:00:00 +0100

Polymorphisms from the TENR-IL2-IL21 block in the 4q27 chromosome were recently associated with type 1 diabetes, celiac disease, rheumatoid arthritis and psoriasis. We undertook this study to investigate the potential role of polymorphisms rs3136534, rs6822844 and rs2069762 ([minus]330 T/G IL2) in multiple sclerosis (MS) (805 patients of Spanish Caucasian origin and 952 health controls). We did not find evidence for association with any single nucleotide polymorphisms (SNPs) tested. Allele and genotype frequencies of the SNPs, which were studied, were similar in DRB1*15-positive or DRB1*15-negative patients. After stratification of MS patients by clinical course, a weak association was observed with rs2069762 G allele and haplotype bearing this allele with secondary progressive MS, althoug...

The effect of substituting alternative grains in the diet on the nutritional profile of the gluten-free diet

Journal of Human Nutrition and Dietetics — Thu, 11 Jun 2009 04:00:00 +0100

Discussion: The inclusion of alternative grain-based products increased the nutrient profile of the gluten-free dietary pattern significantly. (Source: Journal of Human Nutrition and Dietetics)

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Gastrointestinal Symptoms and Well-Being of Adults Living on a Gluten-Free Diet: A Case for Nursing in Celiac Disease.

Gastroenterology Nursing — Tue, 09 Jun 2009 17:35:26 +0100

Page: 196DOI: 10.1097/SGA.0b013e3181a85e7bAuthors: Roos, Susanne MSc, RN; Karner, Anita PhD, RN; Hallert, Claes PhD, MD (Source: Gastroenterology Nursing)

Type 1 diabetes mellitus, celiac disease, systemic lupus erythematosus and systemic scleroderma in a 15-year-old girl

Rheumatology International — Tue, 09 Jun 2009 12:38:58 +0100

We report a case of an association of four autoimmune diseases in a 15-year-old girl and we discuss the etiopathogenic of this association and difficulties of treatment. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00296-009-0988-2Authors Héla Zeglaoui, Farhat Hached Hospital Rheumatology Department Sousse TunisiaHanène Landolsi, Faculty of Pharmacy University of Monastir Monastir TunisiaAmani Mankai, Faculty of Pharmacy University of Monastir Monastir TunisiaIbtissem Ghedira, Farhat Hached Hospital Laboratory of Immunology Sousse TunisiaElyès Bouajina, Farhat Hached Hospital Rheumatology Department Sousse Tunisia Journal Rheumatology InternationalOnline ISSN 1437-160XPrint ISSN 0172-8172 (Source: Rheumatology International)

The prognostic importance of pathologically involved celiac node metastases in node-positive patients with carcinoma of the distal esophagus or gastroesophageal junction: a surgical series from the Mayo Clinic

Diseases of the Esophagus — Tue, 09 Jun 2009 04:00:00 +0100

The management of esophageal cancer with involvement of celiac lymph nodes is controversial. The purpose of this retrospective study was to evaluate the clinical importance of metastases to celiac lymph nodes in patients with carcinoma of the distal esophagus or gastroesophageal junction (GEJ) who undergo surgical treatment with curative intent. We reviewed the medical records of 310 patients who underwent definitive esophagectomy at the Mayo Clinic, Rochester, Minnesota, between 1976 and 1999 for carcinoma of the distal esophagus or GEJ. The disease location was distal esophagus in 163 and GEJ in 147. Fifty-two patients (17%) were found to have celiac node involvement. The survival of these patients was compared with that of 97 N0 patients and 161 N1 patients without celiac node involveme...

Cerebellar signs in celiac disease

Neurology — Mon, 08 Jun 2009 04:00:00 +0100

(Source: Neurology)

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

The Journal of Experimental Medicine — Mon, 08 Jun 2009 04:00:00 +0100

Many human genes have adapted to the constant threat of exposure to infectious agents; according to the "hygiene hypothesis," lack of exposure to parasites in modern settings results in immune imbalances, augmenting susceptibility to the development of autoimmune and allergic conditions. Here, by estimating the number of pathogen species/genera in a specific geographic location (pathogen richness) for 52 human populations and analyzing 91 interleukin (IL)/IL receptor genes (IL genes), we show that helminths have been a major selective force on a subset of these genes. A population genetics analysis revealed that five IL genes, including IL7R and IL18RAP, have been a target of balancing selection, a selection process that maintains genetic variability within a population. Previous identific...

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Missing Celiac Disease in Family Medicine: The Importance of Hypothesis Generation

Medical Decision Making — Mon, 08 Jun 2009 04:00:00 +0100

Conclusions. Most physicians never considered celiac disease. Information inconsistent with the favorite IBS diagnosis was overlooked. Reviewing the case did not prompt physicians to consider celiac disease, re-evaluate the evidence, or rethink the IBS diagnosis. (Source: Medical Decision Making)

Back pain and sacroiliitis in long-standing adult celiac disease: a cross-sectional and follow-up study

Rheumatology International — Sat, 06 Jun 2009 10:01:54 +0100

Abstract There have been only scattered reports suggesting that musculoskeletal manifestations including back pain and sacroiliac joint involvement may be associated with celiac disease. In order to confirm this issue in a larger cohort, rheumatic manifestations were analyzed in 21 adult celiac patients using a comprehensive clinical, laboratory and radiological analysis. The diagnosis of celiac disease was based on the histopathology of jejunal biopsy specimens. The mean duration of celiac disease was 15 (0–31) years. All patients were currently on gluten-free diet and none of the patients had gastrointestinal symptoms at the time of the study. Using various imaging techniques, involvement of the sacroiliac joints was confirmed in 70% of celiac patients. Imaging re...

Improved diagnosis for coeliac disease urged

Management in Practice — Sat, 06 Jun 2009 07:13:23 +0100

Government urged to ensure that doctors follow its new guidelines on the recognition and diagnosis of the condition (Source: Management in Practice)

Coeliac tests are backed by NICE

HealthcareRepublic GP News — Fri, 05 Jun 2009 00:00:00 +0100

Persistent GI symptoms and prolonged fatigue are among signs that should alert GPs to a possible diagnosis of coeliac disease, NICE has said. (Source: HealthcareRepublic GP News)

Isolation and culture of fibroblasts from endoscopic duodenal biopsies of celiac patients

Journal of Translational Medicine — Thu, 04 Jun 2009 04:00:00 +0100

Conclusion: For the first time this study demonstrates the feasibility of culturing primary fibroblast cell from endoscopic duodenal biopsies in celiac and non-celiac subjects, opening a new window of opportunity in studies intended to establish the role of fibroblasts as a possible partaker in the pathogenesis of the celiac mucosal damage. (Source: Journal of Translational Medicine)

MedWorm Supporter Message: Find a vast selection of gluten free food and GF cookbooks at the Sensible Celiac.

Could You Be Missing Celiac Disease in Your Patients?

Medscape Gastroenterology Headlines — Wed, 03 Jun 2009 20:46:43 +0100

One in 133 people have celiac disease, but many go undiagnosed. Medscape Nurses (Source: Medscape Gastroenterology Headlines)

Prometheus Announces New Findings Regarding Patients At Risk For Celiac Disease At DDW

Health News from Medical News Today — Wed, 03 Jun 2009 08:00:00 +0100

Prometheus Laboratories Inc., a specialty pharmaceutical and diagnostic company, announced new findings regarding a correlation between an important serologic marker used in the detection of Crohn's disease and particular genetic markers in patients at risk for celiac disease. (Source: Health News from Medical News Today)

Testing for Celiac Disease in Children With Down Syndrome

AAP Grand Rounds — Mon, 01 Jun 2009 04:00:00 +0100

(Source: AAP Grand Rounds)

Disorders of intestinal secretion and absorption

Best Practice & Research. Clinical Gastroenterology — Mon, 01 Jun 2009 04:00:00 +0100

The gastrointestinal tract possesses a huge epithelial surface area and performs many different tasks. Amongst them are the digestive and absorptive functions. Disorders of intestinal absorption and secretion comprise a variety of different diseases, e.g. coeliac disease, lactase deficiency or Whipple’s disease. In principle, impaired small intestinal function can occur with or without morphological alterations of the intestinal mucosa. Therefore, in the work up of a malabsorptive syndrome an early small intestinal biopsy is encouraged in conjunction with breath tests and stool analysis to guide further management. In addition, there is an array of functional tests, the clinical availability of which becomes more and more limited. In any case, early diagnosis of the underlying pathophysi...