MedWorm: Augmentin

Actinomycetoma of the chest wall attributed to Nocardia nova after reconstructive surgery.

Dermatol Online J — Mon, 06 Feb 2012 12:54:18 +0100

Authors: Antunes J, Pacheco D, Travassos R, Sequeira H, Filipe P, Marques MS Abstract A 29-year-old man, presented with multiple ulcers, nodules, abscesses, fistulae, and atrophic scars, over the right chest wall. Six years prior, the patient had a car accident, which resulted in skin loss of the right arm, shoulder, thoracic wall. In addition, he suffered a supracondylar fracture; orthopedic surgery and skin grafts were required. Material discharging from sinus tracts was obtained for mycological and bacteriological studies. Direct microscopic examination revealed small white grains. Cultures on Sabouraud and Lowenstein-Jensen media isolated orange-white colonies suggestive of Nocardia. PCR assay identified Nocardia nova. Thoracic and right upper limb CT showed signs of chronic os...

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Multidrug-Resistant, NAP2 Clostridium difficile was the Predominant Toxigenic, Hospital-Acquired Strain in the Province of Manitoba, Canada in 2006-2007.

Journal of Medical Microbiology — Thu, 02 Feb 2012 05:00:00 +0100

The objective of the current study was to determine if the antimicrobial susceptibility profile or genotype of hospital-acquired isolates of Clostridium difficile differed from isolates causing community-acquired disease. Five hundred diarrheal stool samples (>2 ml, one sample per patient) from patients across Manitoba, Canada in 2006-2007 that were reported as C. difficile toxin-positive were cultured and resulted in 432 isolates of toxin-positive C. difficile for analysis. Of the 432 isolates, acquisition status could be determined for 235 (54.4%) isolates; 182 (77.4%) were hospital-acquired and 53 (22.6%) were community-acquired. North American Pulsotype (NAP) designations based on SmaI pulsed-field gel electrophoresis could be defined for 52% of the 432 isolates with NAP2 (n = 122) ...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Physicians Total Care, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 02 Feb 2012 05:00:00 +0100

Updated Date: Feb 2, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Sandoz Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 26 Jan 2012 05:00:00 +0100

Updated Date: Jan 26, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Comparative epidemiology of CTX-M-14 and CTX-M-15 producing Escherichia coli: Association with distinct demographic groups in the community in New Zealand

European Journal of Clinical Microbiology and Infectious Diseases — Tue, 24 Jan 2012 06:53:27 +0100

Abstract Extended spectrum beta-lactamase producing E. coli (ESBL-EC) are an emerging public health issue. In New Zealand (NZ), bla CTX-M-14 and bla CTX-M-15 are the most common ESBL genes. Although many studies describe risk factors for ESBL-EC, few describe risk factors for specific ESBL genes. Between January 2006 and December 2007, we characterized 108 consecutive, non-duplicate isolates of ESBL-EC at the Auckland Hospital laboratory. Demographic and clinical data were recorded. Of the 108, 54.6% (59) were CTX-M-15-EC, 26.9% (29) were CTX-M-14-EC and 12.09% were CTX-M-9 (13). The remaining seven isolates carried CTX-M-3 (3; 2.7%), CTX-M-65 (2; 1.8%), CTX-M-27 (1; 0.9%) and CTX-M-57 (1; 0.9%). CTX-M-15-EC were more likely than CTX-M-14-EC to be fluoroquinolone-resistant...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [NorthStar Rx LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 24 Jan 2012 05:00:00 +0100

Updated Date: Jan 24, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Aurobindo Pharma Limited]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 24 Jan 2012 05:00:00 +0100

Updated Date: Jan 24, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [NorthStar Rx LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 18 Jan 2012 05:00:00 +0100

Updated Date: Jan 18, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Preferred Pharmaceuticals, Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 13 Jan 2012 05:00:00 +0100

Updated Date: Jan 13, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder [CBSCHEM LIMITD]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 13 Jan 2012 05:00:00 +0100

Updated Date: Jan 13, 2012 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Children diagnosed with otitis media by an otoscopist benefited from antibiotics but suffered more side effects

Archives of Disease in Childhood - Education and Practice — Wed, 11 Jan 2012 05:00:00 +0100

Study designDesign Randomised placebo-controlled trial. Allocation Allocation sequence computer-generated random number list. Blinding Physicians, parents/caregivers. Study questionSetting Southwest Finland, community based. Patients 319 children aged 6–35 months diagnosed with acute otitis media by a qualified otoscopist. Intervention 161 infants assigned to amoxicillin–clavulanate 40 mg/kg/dose (clavulanate 5.7 mg/kg) for 7 days. 158 assigned to placebo. Outcomes Primary outcome was treatment failure (no overall improvement, no improvement in otoscopic signs, perforation, severe infection requiring antibiotics, adverse reaction); secondary outcomes included time to initiation of open label antibiotics and the development of contralateral otitis media. Follow-up period Until ...

Moxifloxacin or Amoxicillin/clavulanate Effective for COPDMoxifloxacin or Amoxicillin/clavulanate Effective for COPD

Medscape Medical News Headlines — Wed, 28 Dec 2011 19:14:29 +0100

Moxifloxacin was as effective as amoxicillin/clavulanic acid for chronic obstructive pulmonary disease (COPD) exacerbations in outpatients in the MAESTRAL trial. Reuters Health Information (Source: Medscape Medical News Headlines)

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [H.J. Harkins Company, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 27 Dec 2011 05:00:00 +0100

Updated Date: Dec 27, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Moxifloxacin or amoxicillin/clavulanate effective for COPD exacerbations

Modern Medicine — Tue, 27 Dec 2011 05:00:00 +0100

NEW YORK (Reuters Health) - Moxifloxacin was as effective as amoxicillin/clavulanic acid for chronic obstructive pulmonary disease (COPD) exacerbations in outpatients in the MAESTRAL trial. (Source: Modern Medicine)

Prevalence of Antimicrobial Resistance among Clinical Isolates of Bacteroides fragilis group in Canada in 2010-2011: CANWARD Surveillance Study.

Antimicrobial Agents and Chemotherapy — Tue, 27 Dec 2011 05:00:00 +0100

Authors: Karlowsky JA, Walkty AJ, Adam HJ, Baxter MR, Hoban DJ, Zhanel GG Abstract Clinical isolates of Bacteroides fragilis group (n = 387) were collected from patients attending nine Canadian hospitals in 2010-2011 and tested for susceptibility to 10 antimicrobial agents using the Clinical and Laboratory Standards Institute (CLSI) broth microdilution method. B. fragilis (59.9%), Bacteroides ovatus (16.3%), and Bacteroides thetaiotamicron (12.7%) accounted for ∼90% of isolates collected. Overall rates of percent susceptibility were: 99.7%, metronidazole; 99.5%, piperacillin-tazobactam; 99.2% imipenem; 97.7%, ertapenem; 92.0%, doripenem; 87.3%, amoxicillin-clavulanate; 80.9%, tigecycline; 65.9%, cefoxitin; 55.6%, moxifloxacin; and 52.2%, clindamycin. Percent susceptibility to cef...

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AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Lake Erie Medical Surgical Supply DBA Quality Care Products LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 22 Dec 2011 05:00:00 +0100

Updated Date: Dec 22, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Aurobindo Pharma Limited]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 22 Dec 2011 05:00:00 +0100

Updated Date: Dec 22, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [PD-Rx Pharmaceuticals, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 20 Dec 2011 05:00:00 +0100

Updated Date: Dec 20, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

amoxicillin and clavulanic acid, Augmentin, Augmentin XR

MedicineNet Medications General — Thu, 15 Dec 2011 07:00:00 +0100

Title: amoxicillin and clavulanic acid, Augmentin, Augmentin XRCategory: MedicationsCreated: 12/31/1997Last Editorial Review: 12/15/2011 (Source: MedicineNet Medications General)

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Response of feline eosinophilic plaques and lip ulcers to amoxicillin trihydrate-clavulanate potassium therapy: a randomized, double-blind placebo-controlled prospective study.

Veterinary Dermatology — Thu, 01 Dec 2011 05:00:00 +0100

In this study, we evaluated the treatment of feline eosinophilic plaques and lip ulcers with amoxicillin trihydrate-potassium clavulanate (Clavamox(®) ; Pfizer Animal Health). Nineteen cats with clinical and cytological findings consistent with eosinophilic plaques and/or lip ulcers were enrolled. Lesions were photographed and their areas measured in square centimetres before and after 21 days of therapy with either flavoured amoxicillin-clavulanate suspension or flavoured placebo suspension. Sixteen cats completed the study, with nine plaque lesions (four treatment and five placebo) and eight lip ulcer lesions (four treatment and four placebo) included in the analysis. All lesions were shown to have infection, with bacterial phagocytosis present on cytological examination. Coagulase-po...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Lek Pharmaceuticals, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 23 Nov 2011 05:00:00 +0100

Updated Date: Nov 23, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Clinical management of ESBL-producing Enterobacteriaceae: the insidious role of fluoroquinolones

European Journal of Clinical Microbiology and Infectious Diseases — Fri, 18 Nov 2011 06:55:57 +0100

Abstract During a review of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae in our Hospital, a huge number of inadequate antimicrobial therapies emerged. The aim of this study is to assess the factors related to such inadequacy. This retrospective analysis was performed on isolates reported by the microbiology laboratory. Medical records were analyzed to assess adequate treatment; inadequacy was evaluated as overall therapy, antibiotic choice, dosage and length of treatment. Linear regression and multivariate analysis were performed to assess any association. One hundred and fifty isolates were analyzed. They were more commonly isolated from urinary samples and from patients admitted to the Internal Medicine Department; E. coli was the most commonly isola...

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AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Teva Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 18 Nov 2011 05:00:00 +0100

Updated Date: Nov 18, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

[Urinary tract infections: antibiotic resistance and clinical follow up.]

Anales de Pediatria — Fri, 18 Nov 2011 05:00:00 +0100

Authors: de Lucas Collantes C, Cela Alvargonzalez J, Angulo Chacón AM, García Ascaso M, Piñeiro Pérez R, Cilleruelo Ortega MJ, Sánchez Romero I Abstract The initial treatment of the urinary tract infections (UTI) is empirical and it is a priority to determine the antibiotic resistance of most common germs in a population. Furthermore, due to the suspicion of acute pyelonephritis the presence of renal scarring should be ruled out as this may lead to further complications. A retrospective longitudinal study was performed on all children under 14 years diagnosed with UTI from January 1 2009 to December 31 2009. The in vitro susceptibility to the most important urinary pathogens was analysed, along with the presence of scars, and a subsequent follow-up. The most frequently isolate...

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Teva Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 17 Nov 2011 05:00:00 +0100

Updated Date: Nov 17, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Chewable [Teva Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 16 Nov 2011 05:00:00 +0100

Updated Date: Nov 16, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Teva Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 16 Nov 2011 05:00:00 +0100

Updated Date: Nov 16, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Characterization of the inhibitor-resistant SHV β-lactamase (SHV-107) in a clinical Klebsiella pneumoniae strain co-producing GES-7 enzyme.

Antimicrobial Agents and Chemotherapy — Mon, 14 Nov 2011 05:00:00 +0100

Authors: Manageiro V, Ferreira E, Cougnoux A, Albuquerque L, Caniça M, Bonnet R Abstract The clinical K. pneumoniae INSRA6884 strain exhibited non-susceptibility to all penicillins tested (MICs of 64 to >2048 μg/ml). The MICs of penicillins were weakly reduced by clavulanate (from 2048 to 512 μg/ml), and tazobactam restored piperacillin susceptibility. Molecular characterization identified the genes bla(GES-7) and a new β-lactamase gene bla(SHV-107), which encoded an enzyme that differed from SHV-1 by the amino acid substitutions Leu35Gln and Thr235Ala. The SHV-107-producing E. coli strain exhibited only a β-lactam resistance phenotype with respect to amoxicillin, ticarcillin and amoxicillin/clavulanate combination. The kinetic parameters of the purified SHV-107 enzyme reve...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [PD-Rx Pharmaceuticals, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 10 Nov 2011 05:00:00 +0100

Updated Date: Nov 10, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Pharmacodynamic evaluation of commonly prescribed oral antibiotics against respiratory bacterial pathogens

BMC Infectious Diseases — Tue, 25 Oct 2011 04:00:00 +0100

Conclusions: The only regimens to achieve high CFR against all three pathogen populations in both scenarios were gatifloxacin 400mg QD, moxifloxacin 400mg QD, and amoxicillin-clavulanate 500mg TID. These data suggest the need for reconsideration of empiric antibiotic regimen selection among adult patients with RTIs in the Sao Paulo area. Additionally, this type of study could be used to optimize prescribing patterns in specific regions in light of emerging resistance. (Source: BMC Infectious Diseases)

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Chewable [Sandoz Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Mon, 24 Oct 2011 05:00:00 +0100

Updated Date: Oct 24, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 20 Oct 2011 05:00:00 +0100

Updated Date: Oct 20, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 20 Oct 2011 05:00:00 +0100

Updated Date: Oct 20, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Powder, For Suspension [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 20 Oct 2011 05:00:00 +0100

Updated Date: Oct 20, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 20 Oct 2011 05:00:00 +0100

Updated Date: Oct 20, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

A prospective clinical trial for assessing the efficacy of a minimally invasive protocol in patients with bisphosphonate-associated osteonecrosis of the jaws

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Mon, 17 Oct 2011 04:00:00 +0100

Conclusions: This conservative protocol seems to provide successful treatment in the vast majority of patients. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

A randomized trial of the efficacy and safety of sequential intravenous/oral moxifloxacin monotherapy versus intravenous piperacillin/tazobactam followed by oral amoxicillin/clavulanate for complicated skin and skin structure infections

Journal of Antimicrobial Chemotherapy — Wed, 12 Oct 2011 04:00:00 +0100

Conclusions Once-daily iv/oral moxifloxacin monotherapy was clinically and bacteriologically non-inferior to iv TZP thrice daily followed by oral AMC twice daily in patients with cSSSIs. (Source: Journal of Antimicrobial Chemotherapy)

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Diagnosis and treatment of acute uncomplicated cystitis.

American Family Physician — Sat, 01 Oct 2011 04:00:00 +0100

Authors: Colgan R, Williams M Abstract Urinary tract infections are the most common bacterial infections in women. Most urinary tract infections are acute uncomplicated cystitis. Identifiers of acute uncomplicated cystitis are frequency and dysuria in an immunocompetent woman of childbearing age who has no comorbidities or urologic abnormalities. Physical examination is typically normal or positive for suprapubic tenderness. A urinalysis, but not urine culture, is recommended in making the diagnosis. Guidelines recommend three options for first-line treatment of acute uncomplicated cystitis: fosfomycin, nitrofurantoin, and trimethoprim/sulfamethoxazole (in regions where the prevalence of Escherichia coli resistance does not exceed 20 percent). Beta-lactam antibiotics, amoxicillin/c...

Synthesis of novel quinoxalinone derivatives by conventional and microwave methods and assessing their biological activity.

Archives of Pharmacal Research — Sat, 01 Oct 2011 04:00:00 +0100

In this study, twenty-one arylaminoquinoxalinone derivatives were synthesized and their antibacterial activities against Staphylococci aureus, Pseudomonas aureus, Escherichia coli, Bacillus subtilis, Salmonella typhi, and Shigella pneumoniae were evaluated relative to known antibiotics; augmentin, ampicillin, and chloramphenicol. The insecticidal activities of the prepared compounds were also investigated against Tribolium castaneum using permethrin as a standard insecticide. The derivatives were synthesized using both conventional and microwave techniques. Their structures were confirmed using spectral techniques and elemental analysis. PMID: 22076760 [PubMed - in process] (Source: Archives of Pharmacal Research)

AMOXICILLIN AND CLAVULANATE POTASSIUM (Amoxicillin And Clavulanate Potassium ) Tablet AMOXICILLIN AND CLAVULANATE POTASSIUMtablet [Apotex Corp.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 27 Sep 2011 05:00:00 +0100

Updated Date: Sep 27, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUM (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Mon, 19 Sep 2011 05:00:00 +0100

Updated Date: Sep 19, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Amoxicillin-clavulanate improves symptoms, reduces treatment failure in select children with acute otitis media and increases risk of diarrhoea

Evidence-Based Medicine — Fri, 16 Sep 2011 04:00:00 +0100

Context The debate about whether to treat acute otitis media (AOM) with antibiotics affects nearly all practicing paediatricians. In 2004, the American Academy of Pediatrics (AAP) recommended watchful waiting, long practiced in European countries, as an option in children 6–23 months old with ‘non-severe’ illness and an ‘uncertain’ diagnosis.1 This recommendation was based on clinical trials showing high rates of spontaneous resolution of symptoms, so that an estimated 7–17 children would need to be treated with antibiotics to improve one child's clinical outcomes. However, limitations of previous trials, including variability in diagnostic criteria, participants' ages and antimicrobial and supportive treatments used, have kept the debate alive.2–4...

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Augmentin XR (Amoxicillin Clavulanic Potassium) - updated on RxList

RxList - New and Updated Drug Monographs — Thu, 15 Sep 2011 07:00:00 +0100

Augmentin XR (Amoxicillin Clavulanic Potassium) drug description - FDA approved labeling for prescription drugs and medications at RxList (Source: RxList - New and Updated Drug Monographs)

Augmentin ES (Amoxicillin Clavulanate Potassium) - updated on RxList

RxList - New and Updated Drug Monographs — Thu, 15 Sep 2011 07:00:00 +0100

Augmentin ES (Amoxicillin Clavulanate Potassium) drug description - FDA approved labeling for prescription drugs and medications at RxList (Source: RxList - New and Updated Drug Monographs)

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 13 Sep 2011 05:00:00 +0100

Updated Date: Sep 13, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

[Consensus document on the diagnosis and treatment of acute tonsillopharyngitis.]

Anales de Pediatria — Tue, 13 Sep 2011 04:00:00 +0100

The objectives of treatment are: the reduction of symptoms, reduce the contagious period, and prevent local suppurative and systemic complications. Ideally, only confirmed cases should receive antibiotics. If there is no possibility to perform a rapid antigen-detection test, or in some cases if the result is negative, it is recommended to perform a culture and, if there is high suspicious index, to prescribe antibiotics. Penicillin is the treatment of choice, although amoxicillin is also accepted as the first option. Amoxicillin/clavulanate is not indicated in any case as empirical treatment. Macrolides are not a first choice antibiotic, and should be reserved for those patients with immediate penicillin allergy reaction or for the treatment of streptococcal carriers. It is of primordial i...

Single-Agent, Broad-Spectrum Fluoroquinolones for the Outpatient Treatment of Low-Risk Febrile Neutropenia (September).

The Annals of Pharmacotherapy — Mon, 22 Aug 2011 23:00:00 +0100

CONCLUSIONS: Use of oral, single-agent, broad-spectrum fluoroquinolones for outpatient treatment of FN in low-risk patients has shown promising results. At this time, this type of therapy should be limited to low-risk patients. Future clinical trials should include larger sample sizes and a comparison with existing first-line oral therapy-oral ciprofloxacin plus amoxicillin/clavulanate. PMID: 21862714 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy)

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AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 16 Aug 2011 05:00:00 +0100

Updated Date: Aug 16, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Horner’s Syndrome in a Child With Otitis Media: An Unusual Complication

Pediatric Neurology — Wed, 10 Aug 2011 22:18:49 +0100

A 7-year-old, previously healthy girl presented to her family physician with a 1-day history of rhinorrhea and mucoid discharge from the left ear. She was diagnosed with otitis externa and received topical antibiotics. The child was brought to the emergency department of our hospital on day 3 of her illness with a unilateral earache and discharge from the ear. Her temperature at presentation was 37.9°C. She was subsequently afebrile, and her blood pressure was normal. Examination of her ears presented evidence of inflammation of the left eardrum. No postauricular redness or swelling, no mastoid tenderness, and no protrusion of the ear were evident. She manifested ptosis of the left eye and a constricted left pupil. The drooping of her left eye had been observed by her parents on day 2 of ...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [RedPharm Drug Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Mon, 08 Aug 2011 05:00:00 +0100

Updated Date: Aug 8, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Rebel Distributors Corp]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 26 Jul 2011 05:00:00 +0100

Updated Date: Jul 26, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Morton Grove Pharmaceuticals, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 22 Jul 2011 05:00:00 +0100

Updated Date: Jul 22, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Analysis of the Antimicrobial Susceptibility of Anaerobic Bacteria Isolated from Endodontic Infections in Brazil during a Period of Nine Years

Journal of Endodontics — Wed, 20 Jul 2011 16:01:29 +0100

Conclusions: The antimicrobial resistance of anaerobes isolated from primary endodontic infections showed an increase throughout a period of time regarding a specific Brazilian population. (Source: Journal of Endodontics)

Endodontic Pathogens Causing Deep Neck Space Infections: Clinical Impact of Different Sampling Techniques and Antibiotic Susceptibility

Journal of Endodontics — Thu, 14 Jul 2011 23:00:00 +0100

Conclusions: The results of our study indicated that a greater number of anaerobes were found when sampling using the aspiration technique. Penicillin G and aminopenicillins alone are not always sufficient for the treatment of severe deep neck space abscesses; beta-lactamase inhibitor combinations are more effective. Bacteria showed significant resistant rates to clindamycin. Thus, its single use in penicillin-allergic patients has to be carefully considered. (Source: Journal of Endodontics)

Non Prescribed Sale of Antibiotics in Riyadh, Saudi Arabia: A Cross Sectional Study

BMC Public Health - Latest articles — Wed, 06 Jul 2011 23:00:00 +0100

Conclusions: We observed that an antibiotic could be obtained in Riyadh without a medical prescription or an evidence-based indication with associated potential clinical risks. Strict enforcement and adherence to existing regulations are warranted. (Source: BMC Public Health - Latest articles)

The Use and Misuse of Antibiotics Leading to Increasing Bacterial Resistance and “Antibiotic Choice Frustration”

Advances in Small Animal Medicine and Surgery — Thu, 30 Jun 2011 23:00:00 +0100

As a veterinary internal medicine consultant, one of the most frustrating calls I receive is the urinary tract infection (UTI) case with a bacterium that appears resistant to everything but the expensive, injectable, renal toxic, or unusual antibiotics such as nitrofurantoin or meropenen. The “overuse and inappropriate use” of antibiotics in people and pets, in particular, the penicillins, cephalosporins, fluoroquinolones, and perhaps trimethoprim-sulfas, is contributing to increased antibiotic resistance. Examples include methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus pseudintermedius (MRSP), which are resistant to all other beta-lactams, such as cephalosporins and amoxicillin-clavulanate and multi-drug-resistant Escherichia coli. (Source: Advances in Small Anim...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Preferred Pharmaceuticals, Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 29 Jun 2011 05:00:00 +0100

Updated Date: Jun 29, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Physicians Total Care, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 29 Jun 2011 05:00:00 +0100

Updated Date: Jun 29, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTIN (Amoxicillin And Clavulante Potassium) Tablet, Film Coated AUGMENTIN (Amoxicillin And Clavulante Potassium) Tablet [Physicians Total Care, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 29 Jun 2011 05:00:00 +0100

Updated Date: Jun 29, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Preferred Pharmaceuticals, Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 24 Jun 2011 05:00:00 +0100

Updated Date: Jun 24, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Comparison of single-dose and multiple-dose antibiotics for lower urinary tract infection in pregnancy

International Journal of Gynaecology and Obstetrics — Tue, 21 Jun 2011 23:00:00 +0100

Abstract: Objective: To compare the efficacy of fosfomycin trometamol, cefuroxime axetil, and amoxicillin clavulanate antibiotics, and to assess the difference in patient compliance, in the treatment of urinary tract infections during pregnancy.Methods: Between September 2007 and May 2008, 90 out of 324 pregnant women with complaints of lower urinary tract infection, who were followed at the outpatient clinic or referred to the emergency department of Vakif Gureba Education and Research Hospital, were enrolled in a prospective study. Patients were randomized into 3 equal groups for treatment with single-dose fosfomycin trometamol, or 5-day courses of amoxicillin clavulanate or cefuroxime axetil. After follow-up, study data were obtained for 28, 27, and 29 patients, respectively.Results: Th...

[Simultaneous determination of serum concentrations of amoxicillin and clavulanate potassium in human blood using high-performance liquid chromatography.]

Journal of Southern Medical University — Sun, 19 Jun 2011 23:00:00 +0100

CONCLUSION: This method is simple, accurate, sensitive, specific and reproducible for analyzing the concentrations of amoxicillin and clavulanate potassium simultaneously in human plasma. PMID: 21690072 [PubMed - as supplied by publisher] (Source: Journal of Southern Medical University)

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Hepatic safety of antibiotics used in primary care

Journal of Antimicrobial Chemotherapy — Thu, 09 Jun 2011 23:00:00 +0100

Antibiotics used by general practitioners frequently appear in adverse-event reports of drug-induced hepatotoxicity. Most cases are idiosyncratic (the adverse reaction cannot be predicted from the drug's pharmacological profile or from pre-clinical toxicology tests) and occur via an immunological reaction or in response to the presence of hepatotoxic metabolites. With the exception of trovafloxacin and telithromycin (now severely restricted), hepatotoxicity crude incidence remains globally low but variable. Thus, amoxicillin/clavulanate and co-trimoxazole, as well as flucloxacillin, cause hepatotoxic reactions at rates that make them visible in general practice (cases are often isolated, may have a delayed onset, sometimes appear only after cessation of therapy and can produce an array of ...

[Antibiotic resistance of pneumococci and H. influenzae isolated from the nasopharyngeal flora of children with acute otitis media between 2006 and 2010.]

Archives de Pediatrie — Wed, 08 Jun 2011 23:00:00 +0100

CONCLUSION: The data in this study (reduction of ßlactamase producing H. influenzae strains and increase of intermediate penicillin pneumococcal strains) should help to change the choice of antibiotics for AOM in children in France, by reducing the role of oral cephalosporins and secondly, by giving frontline amoxicillin±clavulanic acid. PMID: 21664804 [PubMed - as supplied by publisher] (Source: Archives de Pediatrie)

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [STAT RX USA LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 01 Jun 2011 05:00:00 +0100

Updated Date: Jun 1, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

National Ambulatory Antibiotic Prescribing Patterns for Pediatric Urinary Tract Infection, 1998-2007

PEDIATRICS — Tue, 31 May 2011 23:00:00 +0100

CONCLUSIONS: Ambulatory care physicians commonly prescribe broad-spectrum antibiotics for the treatment of pediatric UTIs, especially for febrile infants in whom complicated infections are more likely. The doubling in use of third-generation cephalosporins suggests that opportunities exist to promote more judicious antibiotic prescribing because most pediatric UTIs are susceptible to narrower alternatives. (Source: PEDIATRICS)

Therapeutic antibiotic use patterns in dogs: observations from a veterinary teaching hospital

The Journal of Small Animal Practice — Tue, 31 May 2011 23:00:00 +0100

Discussion: Clinicians use a variety of tools when deciding whether or not to prescribe an antibiotic and which antibiotic to use. As in human medicine, there is likely overuse and inappropriate use of antibiotics in veterinary medicine. Veterinarians should engage in discussions regarding clinically applicable guidelines for appropriate antibiotic use. (Source: The Journal of Small Animal Practice)

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Treatment of Acute Otitis Media in Children Under 2 Years of Age: Hoberman A, Paradise JL, Rockette HE, et al. N Engl J Med 2011;364:105–15.

The Journal of Emergency Medicine — Tue, 31 May 2011 23:00:00 +0100

The goal of this prospective, randomized control trial was to determine the affect of amoxicillin-clavulanate therapy on the clinical course of acute otitis media among children 6–23 months of age. Children were eligible if they had at least two doses of pneumococcal conjugate vaccine, and were diagnosed with acute otitis media via three criteria: symptoms rated by parents at least 3 on the Acute Otitis Media Severity of Symptoms Scale (AOM-SOS) with an onset within the previous 48 h, the presence of a middle-ear effusion and marked bulging of the tympanic membrane or bulging accompanied by otalgia or membrane erythema. Patients were excluded if they had an allergy to amoxicillin, had other chronic illnesses, had a dose of any antimicrobial within the previous 36 h, or otalgia for longer...

Letters

Pediatric News — Tue, 31 May 2011 23:00:00 +0100

I read the ID Consult on acute otitis media (AOM) article (“Observation Option for AOM: A Second Look,” April 2011, p. 12) with great interest. I respectfully but vigorously disagree with Dr. Michael E. Pichichero's statement, “I don't see how any clinician can withhold antibiotic treatment in good conscience.” I am a general practice pediatrician. I own a Welch Allyn MacroView and feel that I usually get an excellent view of the tympanic membrane. I have seen many clearly bulging red tympanic membranes with effusion, sudden onset of fever, and crying, that resolved in 8 hours or less (or at least the erythema, fever, and fussiness did). I am not against treating some severe AOM, but would continue to do so selectively. I also believe it is important to include the parents in this ...

Aetiology of community-acquired urinary tract infection and antimicrobial susceptibility patterns of uropathogens isolated.

Singapore Medical Journal — Tue, 31 May 2011 23:00:00 +0100

Conclusion: Empirical treatment of community-acquired UTI with cotrimoxazole, ciprofloxacin, cephalothin and ampicillin is inadequate. Amoxicillin/clavulanate should be the drug of choice for empirical treatment instead. PMID: 21731993 [PubMed - in process] (Source: Singapore Medical Journal)

Efficacy and tolerability of systemic methylprednisolone in children and adolescents with chronic rhinosinusitis: A double-blind, placebo-controlled randomized trial

Journal of Allergy and Clinical Immunology — Sun, 29 May 2011 23:00:00 +0100

Conclusion: Oral methylprednisolone is well tolerated and provides added benefit to treatment with antibiotics for children with CRS. (Source: Journal of Allergy and Clinical Immunology)

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated [Cardinal Health]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 26 May 2011 05:00:00 +0100

Updated Date: May 26, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Bacterial etiology and serotypes of acute otitis media in Mexican children.

Vaccine — Sun, 15 May 2011 23:00:00 +0100

Authors: Parra MM, Aguilar GM, Echaniz-Aviles G, Rionda RG, de Los Angeles Meza Estrada M, Cervantes Y, Pirçon JY, Van Dyke MK, Colindres RE, Hausdorff WP Streptococcus pneumoniae and Haemophilus influenzae have been consistently reported to be the two major bacterial pathogens responsible for acute otitis media (AOM), mainly from studies in the US and Europe. However, data on bacterial pathogens causing AOM in Latin America are limited. Understanding the relative importance of these pathogens in a specific setting, the serotype distribution, and their antibiotic susceptibility levels is important to provide local vaccine and treatment recommendations. We therefore conducted a prospective, multi-center, tympanocentesis-based epidemiological study of Mexican children three months to le...

Acute Community Acquired Pneumonia in Emergency Room

Indian Journal of Pediatrics — Tue, 03 May 2011 16:05:00 +0100

Abstract Community acquired pneumonia is the leading killer of children under the age of 5 years. In ER, a diagnosis of pneumonia may be made and the severity graded on basis of WHO’s classification for pneumonia in children up to 5 years of age. It relies on age-specific respiratory rate, presence of lower chest indrawing and signs of severe illness. A diagnosis of pneumonia is made if a febrile child has history of cough and difficult or rapid breathing and a respiratory rate above age specific threshold; however, signs of airway obstruction should be ruled out. Severe pneumonia is diagnosed if with the above features lower chest wall retraction is present; nonetheless, all infants below 2 months and children with moderate to severe malnutrition with pne...

Antimicrobial Resistance in Urinary Tract Pathogens in Canada from 2007 to 2009: CANWARD Surveillance Study.

Antimicrobial Agents and Chemotherapy — Sun, 01 May 2011 23:00:00 +0100

Authors: Karlowsky JA, Lagacé-Wiens PR, Simner PJ, Decorby MR, Adam HJ, Walkty A, Hoban DJ, Zhanel GG From January 2007 to December 2009 an annual Canadian national surveillance study (CANWARD) tested 2943 urinary culture pathogens for antimicrobial susceptibilities following Clinical and Laboratory Standards Institute (CLSI) guidelines. The most frequently isolated urinary pathogens (n, % of all isolates) were Escherichia coli (1581, 54%), enterococci (410, 14%), Klebsiella pneumoniae (274, 9%), Proteus mirabilis (122, 4%), Pseudomonas aeruginosa (100, 3%), and Staphylococcus aureus (80, 3%). Rates of susceptibility to trimethoprim-sulfamethoxazole (SXT) were 78%, 86%, 84%, and 93%, respectively, for E. coli, K. pneumoniae, P. mirabilis, and S. aureus. Rates of susceptibility to nitr...

[Acute otitis media in ambulatory practice: Epidemiological and clinical characteristics after 7 valent pneumococcal conjugate vaccine (PCV7) implementation.]

Archives de Pediatrie — Thu, 28 Apr 2011 23:00:00 +0100

CONCLUSION: Despite PCV7 implementation, AOM remains a very frequent childhood infection and a major reason for ATB prescriptions. PMID: 21531540 [PubMed - as supplied by publisher] (Source: Archives de Pediatrie)

AMOXICILLIN AND CLAVULANATE POTASSIUM (Amoxicillin And Clavulanate Potassium) Powder, For Suspension [Preferred Pharmaceuticals, Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 26 Apr 2011 05:00:00 +0100

Updated Date: Apr 26, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Acute parotitis after ERCP

Gastrointestinal Endoscopy — Mon, 25 Apr 2011 23:00:00 +0100

A 50-year-old woman presented with biliary colic. Serum bilirubin, alanine aminotransferase, and aspartate aminotransferase levels were normal, but the serum alkaline phosphatase was 550 IU/L. US of the abdomen revealed gallbladder calculi and a calculus in the common duct. Endoscopic retrograde cholangiography was done after intravenous midazolam was administered for conscious sedation. Cholangiography, with diatrizoate as the contrast agent, revealed a 10-mm stone in the common duct (). Sphincterotomy and basket extraction of the stone was performed. Four hours after the procedure, fever and erythematous, tender swelling of the left parotid gland acutely developed (). There was no overlying crepitus. A diagnosis of acute parotitis was made. She had no viral prodrome or history of Sjögre...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Multilayer, Extended Release [Sandoz Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 19 Apr 2011 05:00:00 +0100

Updated Date: Apr 19, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Bacteriological findings and antimicrobial resistance in odontogenic and non-odontogenic chronic maxillary sinusitis.

Journal of Medical Microbiology — Thu, 14 Apr 2011 23:00:00 +0100

In this study, 20% of chronic maxillary sinusitis were associated with a dental origin, and sinus lift procedures were the main etiological factor. Our microbiological findings showed that all specimens from chronic maxillary sinusitis were polymicrobial. Sixty aerobes and 75 anaerobes were recovered from the 47 cases of non-odontogenic sinusitis (2.9 bacteria/specimen); 15 aerobes and 25 anaerobes were isolated from the 12 patients with odontogenic sinusitis (3.3 bacteria/specimen). The predominant aerobes were Staphylococcus aureus (27) and Streptococcus pneumoniae (16), while the more frequent anaerobes were Peptostreptococcus spp. (31) and Prevotella spp. (30). Haemophilus influenzae and Moraxella catarrhalis were absent in sinusitis associated with a dental origin. Overall, 22% of S. ...

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 14 Apr 2011 05:00:00 +0100

Updated Date: Apr 14, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Powder, For Suspension [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 14 Apr 2011 05:00:00 +0100

Updated Date: Apr 14, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 14 Apr 2011 05:00:00 +0100

Updated Date: Apr 14, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUM EXTENDED RELEASE (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 14 Apr 2011 05:00:00 +0100

Updated Date: Apr 14, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Susceptibility to Amoxicillin-Clavulanate-Induced Liver Injury Is Influenced by Multiple HLA Class I and II Alleles

Gastroenterology — Mon, 11 Apr 2011 23:00:00 +0100

Conclusions: Class I and II HLA genotypes affect susceptibility to AC-DILI, indicating the importance of the adaptive immune response in pathogenesis. The HLA genotypes identified will be useful in studies of the pathogenesis of AC-DILI but have limited utility as predictive or diagnostic biomarkers because of the low positive predictive values. (Source: Gastroenterology)

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Mon, 11 Apr 2011 05:00:00 +0100

Updated Date: Apr 11, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [Dr Reddys Laboratories Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Mon, 11 Apr 2011 05:00:00 +0100

Updated Date: Apr 11, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Adult native septic arthritis: a review of 10 years of experience and lessons for empirical antibiotic therapy

Journal of Antimicrobial Chemotherapy — Sun, 10 Apr 2011 23:00:00 +0100

Conclusions Amoxicillin/clavulanate or cefuroxime would be adequate for empirical coverage of large-joint septic arthritis in our area. A broad-spectrum antibiotic would be significantly superior for small-joint infections in diabetics. Systematic coverage of MRSA is not justified, but should be considered for known carriers. These recommendations are applicable to our local setting. They might also apply to hospitals sharing the same epidemiology. (Source: Journal of Antimicrobial Chemotherapy)

Efficacy of simulated cefditoren vs. amoxicillin/clavulanate free concentrations in countering intra-strain ftsI gene diffusion in H. influenzae.

Antimicrobial Agents and Chemotherapy — Sun, 03 Apr 2011 23:00:00 +0100

This study explores effects of cefditoren (CDN) versus amoxicillin/clavulanic acid (AMC) on the evolution (within a single strain) of total- and recombined- populations derived from intra-strain ftsI gene diffusion in β-lactamase positive (BL+) and negative (BLneg) H. influenzae. DNA from BLNAR (DNABLNAR) and BLPACR (DNABLPCAR) isolates was extracted and added to a 10(7) cfu/ml suspension of one BL+ (MIC-μg/ml- CDN=0.007; AMC=1) or one BLneg (MIC-μg/ml- CDN=0.015; AMC=0.5) in HTM. The mixture was 3h-incubated and inoculated in a two-compartmental computerized device simulating over 24h free serum concentrations of CDN (400 mg, bid) or AMC (875/125 mg, tid). Controls: antibiotic-free simulations. Colony counts were performed, total-population and recombined-population differentiated, and...

A multicentre surveillance study on the characteristics, bacterial aetiologies and in vitro antibiotic susceptibilities in patients with acute exacerbations of chronic bronchitis

Respirology — Wed, 30 Mar 2011 23:06:55 +0100

Conclusions: Gram‐negative bacteria including Klebsiella spp., P. aeruginosa and Acinetobacter spp. constitute a large proportion of pathogens identified in patients with AECB in some Asian countries. Surveillance on the local prevalence and antibiotic resistance of these organisms is important in guiding appropriate choice of antimicrobials in the management of AECB. (Source: Respirology)

Dr Reddy's acquires GSK's US penicillin facility

The Economic Times Healthcare and Biotech News — Wed, 30 Mar 2011 08:42:34 +0100

Dr Reddy's Laboratories has acquired GlaxoSmithKline's US penicillin manufacturing facility and the rights to the Augmentin and Amoxil brands. (Source: The Economic Times Healthcare and Biotech News)

Otalgia and eschar in the external auditory canal in scrub typhus complicated by acute respiratory distress syndrome and multiple organ failure

BMC Infectious Diseases — Tue, 29 Mar 2011 23:00:00 +0100

We reported a 23-year-old man who had an eschar in the EAC in scrub typhus presenting with right ear pain after training in the jungle and an 11-day history of intermittent fever up to 39 degree C. Amoxicillin/clavulanate was prescribed for otitis media at a local clinic. Skin rash and abdominal cramping pain with diarrhea appeared on the sixth day of fever. He was referred to our institution due to progressive dysponea and cough. Physical examination showed an eschar in the right EAC, icteric sclera and bilateral basal rales. Thrombocytopenia, impaired liver function, acute renal failure and positive Weil-Felix reaction were noted. Doxycycline was prescribed for scrub typhus. Fever subsided the next day and he was discharged on day 7. (Source: BMC Infectious Diseases)

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Localized acute generalized exanthematous pustulosis with amoxicillin and clavulanic acid.

The Turkish Journal of Pediatrics — Tue, 01 Mar 2011 00:00:00 +0100

Authors: Ozkaya-Parlakay A, Azkur D, Kara A, Yildiz Y, Orhan D, Cengiz AB, Ersoy-Evans S Abstract Acute generalized exanthematous pustulosis (AGEP) is a rare skin disorder, characterized by acute development of numerous, pin-head sized, nonfollicular pustules on erythematous skin, with high fever and neutrophilia. The condition is frequently caused by hypersensitivity reaction to drugs or viral infections. Diagnosis is established according to clinical and histological criteria. Herein, we report a 17-year-old girl with localized AGEP related to the use of amoxicillin-clavulanate. PMID: 21853667 [PubMed - in process] (Source: The Turkish Journal of Pediatrics)

AMOXICILLIN AND CLAVULANATE POTASSIUM (Amoxicillin And Clavulanate Potassium) Powder, For Suspension [Preferred Pharmaceuticals, Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 17 Feb 2011 05:00:00 +0100

Updated Date: Feb 17, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [GlaxoSmithKline LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 15 Feb 2011 05:00:00 +0100

Updated Date: Feb 15, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Powder, For Suspension [GlaxoSmithKline LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 15 Feb 2011 05:00:00 +0100

Updated Date: Feb 15, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet [GlaxoSmithKline LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 15 Feb 2011 05:00:00 +0100

Updated Date: Feb 15, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Diagnosis and treatment of urinary tract infections in children.

American Family Physician — Tue, 15 Feb 2011 00:00:00 +0100

Authors: White B Acute urinary tract infections are relatively common in children, with 8 percent of girls and 2 percent of boys having at least one episode by seven years of age. The most common pathogen is Escherichia coli, accounting for approximately 85 percent of urinary tract infections in children. Renal parenchymal defects are present in 3 to 15 percent of children within one to two years of their first diagnosed urinary tract infection. Clinical signs and symptoms of a urinary tract infection depend on the age of the child, but all febrile children two to 24 months of age with no obvious cause of infection should be evaluated for urinary tract infection (with the exception of circumcised boys older than 12 months). Evaluation of older children may depend on the clinical presen...

Risk factors for fluoroquinolone-resistant Escherichia coli in adults with community-onset febrile urinary tract infection

Journal of Antimicrobial Chemotherapy — Thu, 10 Feb 2011 00:00:00 +0100

Conclusions Recent hospitalization, urinary catheter and fluoroquinolone use in the past 6 months were independent risk factors for fluoroquinolone resistance in community-onset febrile E. coli UTI. Contact with animals or hospitalized household members was not associated with fluoroquinolone resistance. Fluoroquinolone resistance may be a marker of broader resistance, including ESBL positivity. (Source: Journal of Antimicrobial Chemotherapy)

Bacterial colonization patterns in neonates transferred from neonatal intensive care units.

International Journal of Hygiene and Environmental health — Thu, 10 Feb 2011 00:00:00 +0100

In conclusion, we found a low prevalence of HRMO and a low incidence of bacterial infections in neonates after transfer from a NICU. There was no significant increase in time in the prevalence of colonization with (resistant) bacteria. A NICU-stay longer than a week was an independent predictor for colonization with bacteria. Based on these observations we have ended standard culturing and nursing in isolation of these patients. PMID: 21316303 [PubMed - as supplied by publisher] (Source: International Journal of Hygiene and Environmental health)

A Multicentre Surveillance Study on the Characteristics, Bacterial Aetiologies and In‐vitro Antibiotic Susceptibilities in Patients With Acute Exacerbations of Chronic Bronchitis

Respirology — Tue, 08 Feb 2011 00:00:00 +0100

Conclusions: Gram‐negative bacteria including Klebsiella spp., Pseudomonas aeruginosa and Acinetobacter spp. constitute a large proportion of pathogens identified in patients with AECB in some Asian countries. Surveillance on the local prevalence and antibiotic resistance of these organisms is important in guiding appropriate choice of antimicrobials in the management of AECB. (Source: Respirology)

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Trials Give Nod to Antibiotics for Certain AOM

Pediatric News — Tue, 01 Feb 2011 00:00:00 +0100

Children with a certain diagnosis of acute otitis media who were treated with amoxicillin-clavulanate recovered more quickly, compared with those who received placebo, results from two large, separate studies demonstrated. (Source: Pediatric News)

Antimicrobial susceptibility of Staphylococcus aureus and Staphylococcus pseudintermedius isolated from various animals.

The Canadian Veterinary Journal — Tue, 01 Feb 2011 00:00:00 +0100

This study characterized the antimicrobial susceptibility of 221 Staphylococcus aureus isolated from various species, and 60 canine Staphylococcus pseudintermedius isolated from 1986 through 2000 at the Western College of Veterinary Medicine (WCVM). Resistance of S. aureus was most common to penicillin (31%) and tetracycline (14%); resistance of S. pseudintermedius to penicillin was present in 8% and to tetracycline in 34% of isolates. Resistance to trimethoprim/sulfamethoxazole was only seen among S. pseudintermedius, and there was no resistance to amoxicillin/clavulanate, ampicillin/sulbactam, cephalothin, amikacin, gentamicin, enrofloxacin, chloramphenicol, or rifampin among any isolate. Inducible clindamycin resistance was found in both S. aureus and S. pseudintermedius, highlighting t...

Single-dose extended-release azithromycin versus a 10-day regimen of amoxicillin/clavulanate for the treatment of children with acute otitis media

International Journal of Infectious Diseases — Thu, 27 Jan 2011 00:00:00 +0100

Conclusions: A single 60-mg/kg dose of azithromycin ER provides near equivalent effectiveness to a 10-day regimen of amoxicillin/clavulanate 90/6.4mg/kg per day in the treatment of children with acute otitis media. (Source: International Journal of Infectious Diseases)

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [TEVA Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 26 Jan 2011 05:00:00 +0100

Updated Date: Jan 26, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [TEVA Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 25 Jan 2011 05:00:00 +0100

Updated Date: Jan 25, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

MedWorm Sponsor Message: Find the best January Sales in the UK.

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Chewable [TEVA Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Mon, 24 Jan 2011 05:00:00 +0100

Updated Date: Jan 24, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Epidemiology of urinary tract infections and antibiotics sensitivity among pregnant women at Khartoum North Hospital

Annals of Clinical Microbiology and Antimicrobials — Tue, 18 Jan 2011 00:00:00 +0100

Conclusion: Escherichia coli were the most prevalent causative organisms and showing multi drug resistance pattern, asymptomatic bacteriuria is more prevalent than symptomatic among pregnant women. Urine culture for screening and diagnosis purpose for all pregnant is recommended. (Source: Annals of Clinical Microbiology and Antimicrobials)

Improving turnaround time for identifying extended spectrum beta-lactamase producing Escherschia coli and Klebsiella pneumoniae: an experience from BD Phoenix automated system.

Journal of Medical Microbiology — Thu, 13 Jan 2011 00:00:00 +0100

Authors: Lebitasy MP, Huang TD, Rodriguez-Villalobos H, Simon A In order to avoid systematic confirmatory test of ESBL, we aimed to consider cases for which the results of BD Epicenter expert system associated to BD Phoenix ESBL test for E. coli and K. pneumoniae would be reliable enough without further testing for ESBL production. From July 2008 to June 2009, all E. coli and K. pneumoniae isolates were prospectively tested for ESBL production by combined disks (CD) method (Neo-sensitabs, Rosco, Denmark) using 3 substrates: cefotaxime 30µg, ceftazidime 30µg, cefepime 30µg with and without clavulanate acid 10µg. We reviewed the AST results of clinical isolates performed on the BD NMIC/ID-51 panel and of the correspondent phenotypical confirmatory test. As ESBLs are inhibited by clav...

Antibiotics Benefit Acute Ear Infections in Young Children

Modern Medicine — Wed, 12 Jan 2011 00:00:00 +0100

Children with acute otitis media appear to benefit from antimicrobial treatment with amoxicillin-clavulanate, according to two articles published in the Jan. 13 issue of the New England Journal of Medicine. (Source: Modern Medicine)

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [TEVA Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 04 Jan 2011 05:00:00 +0100

Updated Date: Jan 4, 2011 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Alarmingly decreasing rates of amoxicillin-clavulanate susceptibility among clinical isolates of Haemophilus influenzae from 2001 to 2009 in a medical center in Taiwan

Journal of Infection — Mon, 27 Dec 2010 00:00:00 +0100

Haemophilus influenzae is an important pathogen causing community-acquired pneumonia (CAP) in adult patients, especially in those with chronic obstructive pulmonary disease. In Taiwan, about 9% of CAP among inpatients and outpatients is caused by H. influenzae, followed by Streptococcus pneumoniae and Mycoplasma pneumoniae. According to antimicrobial resistance surveillance in Taiwan from 1998 to 1999 and during 2005, more than half of H. influenzae isolates (55–56%) produced β-lactamase, which is the principal mechanism of resistance to amoxicillin and ampicillin. Nearly all (99%) H. influenzae isolates tested were susceptible to amoxicillin-clavulanate. The 2007 international and 2006 Taiwanese guidelines on the treatment of CAP recommend ampicillin-sulbactam, amoxicillin-clavulanate,...

Antimicrobial resistance in community-acquired urinary tract infections: results from the Korean Antimicrobial Resistance Monitoring System

Journal of Infection and Chemotherapy — Tue, 07 Dec 2010 13:46:31 +0100

Abstract The Korean Antimicrobial Resistance Monitoring System was established and the first nationwide surveillance of bacterial uropathogens was conducted during the period from January 2008 to June 2009. With the cooperation of 34 medical centers throughout South Korea, a total of 1994 strains belonging to clinically relevant bacterial uropathogens were collected from patients with community-acquired urinary tract infections (UTIs). To compare with past data, understand a trend of antimicrobial resistance, and ultimately determine new regimens for empirical treatment of uncomplicated cystitis, the antimicrobial susceptibilities against Escherichia coli in uncomplicated cystitis to commonly prescribed drugs were investigated. In uncomplicated cystitis, the most prevalent c...

AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Chewable [TEVA Pharmaceuticals USA Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 03 Dec 2010 05:00:00 +0100

Updated Date: Dec 3, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AUGMENTINXR (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [Physicians Total Care, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 23 Nov 2010 05:00:00 +0100

Updated Date: Nov 23, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMsuspension [Rebel Distributors Corp.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 23 Nov 2010 05:00:00 +0100

Updated Date: Nov 23, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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AUGMENTIN (Amoxicillin And Clavulante Potassium) Tablet, Film Coated AUGMENTIN (Amoxicillin And Clavulante Potassium) Tablet [Physicians Total Care, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 23 Nov 2010 05:00:00 +0100

Updated Date: Nov 23, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension [Rebel Distributors Corp.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 23 Nov 2010 05:00:00 +0100

Updated Date: Nov 23, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

High rates of quinolone resistance among urinary tract infections in the ED

The American Journal of Emergency Medicine — Mon, 15 Nov 2010 05:00:00 +0100

Conclusions: We report high rates of quinolone resistance in ED patients with UTIs at our institution. For patients with risk factors for quinolone resistance, empiric therapy with cephalosporins or nitrofurantoin may be preferred. Urine culture and susceptibility testing should be performed to guide definitive therapy for HA-UTIs. (Source: The American Journal of Emergency Medicine)

Supernumerary, ectopic tooth in the maxillary antrum presenting with recurrent haemoptysis

Head and Face Medicine — Thu, 11 Nov 2010 00:00:00 +0100

Conclusion: Recurrent haemoptysis has not been described as a presentation for a supernumerary, ectopic tooth in literature before. We recommend that in patients with sinusitis-type of opacification of maxillary antrum and whose condition is refractory to conventional medical treatment, consideration should be given to the investigation of possible underlying anomalies as the cause of such symptoms. Presence of foreign bodies and ectopic teeth in paranasal sinuses can be reliably excluded with the use of appropriate radiological imaging and endoscopic examination. (Source: Head and Face Medicine)

AMOXICILLIN AND CLAVULANATE POTASSIUM (Amoxicillin And Clavulanate Potassium) Powder, For Suspension [Preferred Pharmaceuticals, Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 10 Nov 2010 05:00:00 +0100

Updated Date: Nov 10, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Is this painful swelling a spider bite?

Consultant Live — Tue, 09 Nov 2010 12:00:00 +0100

For 5 days, a 68-year-old woman has been bothered by a painful swelling on her left cheek. There is no history of trauma or bite. She takes a diuretic for mild hypertension. Amoxicillin/clavulanate was started 2 days earlier pending the results of a bacterial culture. What is the likely diagnosis? (Source: Consultant Live)

Augmentin (Amoxicillin Clavulanate) - updated on RxList

RxList - New and Updated Drug Monographs — Mon, 08 Nov 2010 07:00:00 +0100

Augmentin (Amoxicillin Clavulanate) drug description - FDA approved labeling for prescription drugs and medications at RxList (Source: RxList - New and Updated Drug Monographs)

Extramural Ectopic Ureter in a Domestic Ferret (Mustela putorius furo)

Journal of Exotic Pet Medicine — Fri, 01 Oct 2010 00:00:00 +0100

Abstract: Ectopic ureter is the most common cause of congenital urinary incontinence in the dog and cat. The occurrence of ectopic ureter in the dog has been estimated to be 0.016%. A 6-month-old ferret was evaluated for urinary incontinence and urine scalding around the perineal and inguinal areas. Ultrasonography showed a nondistended urinary bladder that contained a possible intraluminal blood clot. Excretory urography revealed a left ectopic ureter. The ferret was initially treated with oral amoxicillin-clavulanate and topical silver sulfadiazine ointment for the perineal and inguinal dermatitis associated with the incontinence. Because of the potential for complications and additional surgery with ureteral transplantation, a left nephroureterectomy was performed. Surgical recovery was...

AUGMENTIN (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated, Extended Release [GlaxoSmithKline LLC]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 14 Sep 2010 05:00:00 +0100

Updated Date: Sep 14, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUMpowder, For Suspension AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Chewable [Sandoz Inc]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 10 Sep 2010 05:00:00 +0100

Updated Date: Sep 10, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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[Case Report] Dangers in the garden

LANCET — Thu, 02 Sep 2010 23:00:00 +0100

In March, 2010, a previously fit and healthy 67-year-old man presented with an 8-day history of fever with rigors, intermittent confusion, lethargy, and shortness of breath. On admission, he was febrile with a temperature of 39°C and had clinical signs of a left-sided pneumonia, accompanied by general abdominal tenderness. His white blood cell count was 14·8×109/L (number of neutrophils was 11·3×109/L, and lymphocyles 0·2×109/L), and C-reactive protein concentration was raised at 475 mg/L. Renal, and liver function were abnormal: urea concentration was 21·6 mmol/L; creatinine 257 μmol/L; sodium 135 mmol/L; potassium 4 mmol/L; aspartate aminotransferase 115 IU/L; alanine aminotransferase 80 IU/L; and bilirubin 56 μmol/L. A chest radiograph showed complete opacification of his left...

Comparative antibiotic failure rates in the treatment of community-acquired pneumonia: Results from a claims analysis.

Advances in Therapy — Wed, 25 Aug 2010 23:00:00 +0100

CONCLUSION|: In a large US sample, treatment failure in CAP appeared to be less likely with quinolones (such as levofloxacin) than azithromycin, an effect particularly marked in high-risk patients (age >/=65 and/or on Medicaid). PMID: 20799007 [PubMed - as supplied by publisher] (Source: Advances in Therapy)

[Review] Best drug treatment for multidrug-resistant and extensively drug-resistant tuberculosis

The Lancet Infectious Diseases — Sun, 22 Aug 2010 23:00:00 +0100

Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis are generally thought to have high mortality rates. However, many cases can be treated with the right combination and rational use of available antituberculosis drugs. This Review describes the evidence available for each drug and discusses the basis for recommendations for the treatment of patients with MDR and XDR tuberculosis. The recommended regimen is the combination of at least four drugs to which the Mycobacterium tuberculosis isolate is likely to be susceptible. Drugs are chosen with a stepwise selection process through five groups on the basis of efficacy, safety, and cost. Among the first group (the oral first-line drugs) high-dose isoniazid, pyrazinamide, and ethambutol are thought of as an adjunct for t...

Melioidosis in an urban-dwelling Taiwanese man with splenic abscesses.

Tropical Doctor — Thu, 12 Aug 2010 23:00:00 +0100

We report a case of melioidosis with splenic abscesses caused by Burkholderia pseudomallei in an urban-dwelling, 54-year-old Taiwanese man. The patient presented with prolonged fever and abdominal pain. A splenectomy was performed, followed by successful treatment with ceftazidime and amoxicillin-clavulanate. The patient recovered fully. PMID: 20709809 [PubMed - as supplied by publisher] (Source: Tropical Doctor)

AMOXICILLIN AND CLAVULANATE POTASSIUMsuspension [West-Ward Pharmaceutical Corp]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 10 Aug 2010 05:00:00 +0100

Updated Date: Aug 10, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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AMOXICILLIN AND CLAVULANATE POTASSIUMtablet, Film Coated [State Of Florida DOH Central Pharmacy]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Fri, 06 Aug 2010 05:00:00 +0100

Updated Date: Aug 6, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

AMOXICILLIN AND CLAVULANATE POTASSIUM (Amoxicillin And Clavulanate Potassium) Tablet, Film Coated [State Of Florida DOH Central Pharmacy]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Thu, 05 Aug 2010 05:00:00 +0100

Updated Date: Aug 5, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Young Girl With Enlarging Tender Neck Mass

Consultant Live — Wed, 04 Aug 2010 12:00:00 +0100

A 6-year-old girl presented with tender mass on the left side of her neck that had enlarged over the past week. Her primary care doctor initially prescribed amoxicillin/clavulanate for suspected bacterial lymphadenitis. The swelling progressed, and a CT scan was ordered. (Source: Consultant Live)

Cochlear Implants in Children: Surgical Site Infections and Prevention and Treatment of Acute Otitis Media and Meningitis

PEDIATRICS — Mon, 02 Aug 2010 15:02:40 +0100

The use of cochlear implants is increasingly common, particularly in children younger than 3 years. Bacterial meningitis, often with associated acute otitis media, is more common in children with cochlear implants than in groups of control children. Children with profound deafness who are candidates for cochlear implants should receive all age-appropriate doses of pneumococcal conjugate and Haemophilus influenzae type b conjugate vaccines and appropriate annual immunization against influenza. In addition, starting at 24 months of age, a single dose of 23-valent pneumococcal polysaccharide vaccine should be administered. Before implant surgery, primary care providers and cochlear implant teams should ensure that immunizations are up-to-date, preferably with completion of indicated vaccines ...

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Decrease in serum valproic acid levels during treatment with ertapenem.

American Journal of Health-System Pharmacy : AJHP — Mon, 26 Jul 2010 11:24:33 +0100

Conclusion After initiation of ertapenem, decreased serum valproic acid levels were observed in two patients. PMID: 20651316 [PubMed - in process] (Source: American Journal of Health-System Pharmacy : AJHP)

Spread of Odontogenic Infections in Port Harcourt, Nigeria

Journal of Oral and Maxillofacial Surgery — Thu, 15 Jul 2010 23:00:00 +0100

Conclusions: Our experience shows that delay in presentation, self-medication, aging, male gender, and unusual causative agents are some of the factors associated with spread. Therefore efforts must be made to further improve public dental awareness. (Source: Journal of Oral and Maxillofacial Surgery)

Prophylactic antibiotics in endoscopic sinus surgery: A short follow-up study.

American Journal of Rhinology and Allergy — Wed, 30 Jun 2010 23:00:00 +0100

CONCLUSION: The use of an antibiotic (amoxicillin/clavulanate) in the postoperative period is able to improve the outcome in the early blood crust healing phase: nasal obstruction and drainage are reduced and the endoscopic score objectively showed a faster recovery. PMID: 20819471 [PubMed - in process] (Source: American Journal of Rhinology and Allergy)

Urinary tract pathogens and resistance pattern

Journal of Clinical Pathology — Wed, 30 Jun 2010 08:50:39 +0100

Conclusion Our data suggest that there has been an increasing resistance trend to the first-line antibiotics like trimethoprim and Augmentin against E coli. In accordance with NICE (National Institute for Health and Clinical Excellence) guidance, each region should monitor resistance patterns to urinary pathogens on a regular basis and use antibiotics with a low resistance pattern. Further studies are required from other centres in the UK to look at similar data. (Source: Journal of Clinical Pathology)

The Viriato Study: Update on Antimicrobial Resistance of Microbial Pathogens Responsible for Community-Acquired Respiratory Tract Infections in Portugal.

Paediatric Drugs — Mon, 28 Jun 2010 23:00:00 +0100

Authors: Melo-Cristino J, Santos L, Silva-Costa C, FriÃ£es A, Pinho MD, Ramirez M, The Viriato study is a prospective, multicentre laboratory-based surveillance study of antimicrobial susceptibility in which 30 microbiology laboratories throughout Portugal are asked to isolate, identify and submit to a central laboratory for testing Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis responsible for community-acquired lower respiratory tract infections and Streptococcus pyogenes from tonsillitis. To monitor changes in antimicrobial resistance patterns of these frequent respiratory pathogens. Susceptibility was determined by disk diffusion (Kirby-Bauer) or using Etest strips following the Clinical and Laboratory Standards Institute guidelines. From 1999 to 2007...

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Acute otitis media: To follow-up or treat?

International Journal of Pediatric Otorhinolaryngology — Fri, 25 Jun 2010 05:40:39 +0100

Abstract: Acute otitis media (AOM) is the most common diagnosis for which antibiotics are prescribed in children. However, due to their widespread use, we are witnesses to increased development of bacterial resistance to antibiotics. The purpose of this study was to evaluate the necessity of antibiotic treatment in patients with AOM. Our study included 314 children, aged between 2 months and 6 years. Children were divided into two groups: the first group included children with less severe forms of AOM, who received symptomatic therapy and “wait-and-see” approach (237 children); the second group presented with purulent ear infection and received antibiotic treatment from the beginning (77 children). After symptomatic therapy, resolution of the disease, without use of any antibiotics, wa...

Rapidly growing neck swelling in the submandibular triangle

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 19 Jun 2010 05:36:59 +0100

A 38-year-old East Indian man was referred to the oral and maxillofacial surgery unit at the University of California, San Francisco (UCSF), for management of a subacute progressive left submandibular swelling. The patient gave a history of developing a small left neck swelling which had increased in size over a 3-week period (). He initially consulted with his primary care physician, who prescribed a 1-week course of tetracycline. He subsequently presented to a local county hospital emergency room before completing the antibiotic course owing to continuous increase in swelling accompanied by difficulty in swallowing and low-grade fever. After several investigations, including a computerized tomographic (CT) scan of the neck, he was diagnosed with lymphadenopathy and discharged with a 10-d...

In reply

Journal of Oral and Maxillofacial Surgery — Fri, 18 Jun 2010 05:43:38 +0100

In my recent letter to the editor, I tried to emphasize the importance of Staphylococcus species bacteria (rather than the classically implicated streptococcal-based infections) in the oral cavity and their possible relations to the very large number of late prosthetic joint infections caused by this group of organisms. Given the sometime resistance of Staphylococcus to β-lactam antibiotics, including amoxicillin and some cephalosporins, the German Society of Orthopaedics and Traumatology has devised an antibiotic regimen (amoxicillin-clavulanate 2 g or clindamycin 600 mg; shortly before and 4 hours after dental care) that is effective against staphylococcal and streptococcal bacteremias that might arise from the oral cavity in association with surgical management of infections. (Source: ...

Comparison of hospital-wide and unit-specific cumulative antibiograms in hospital- and community-acquired infection

Infection — Wed, 16 Jun 2010 07:16:36 +0100

Conclusions Hospital-wide antibiograms reflect the susceptibility pattern for a specific unit with respect to community-acquired, but not to hospital-acquired strains. Antibiograms adjusted to these parameters may be useful in guiding the choice of empirical antibacterial therapy. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-010-0033-0Authors F. Lamoth, Centre Hospitalier Universitaire Vaudois and University of Lausanne Infectious Diseases Service Rue du Bugnon 46 1011 Lausanne SwitzerlandA. Wenger, Centre Hospitalier Universitaire Vaudois and University of Lausanne Institute of Microbiology Lausanne SwitzerlandG. Prod’hom, Centre Hospitalier Universitaire Vaudois and University of Lausanne Institute of Microbiology Lau...