MedWorm: Botox

Treatment of Hyperhidrosis With Botox

Medscape Ob/Gyn & Women's Health Headlines — Tue, 16 Mar 2010 14:40:46 +0100

In this video commentary, Dr. Marina Peredo demonstrates the use of Botox for severe primary axillary hyperhidrosis. Medscape Dermatology (Source: Medscape Ob/Gyn & Women's Health Headlines)

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BOTOX (Onabotulinumtoxina) Injection, Powder, Lyophilized, For Solution [Allergan, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Tue, 16 Mar 2010 05:00:00 +0100

Updated Date: Mar 16, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

Dysport Takes On Botox With Aggressive Rebates

NYT — Fri, 12 Mar 2010 05:39:29 +0100

Medicis has started a new marketing campaign that pits its wrinkle-smoother, Dysport, directly against Botox. It makes bioethicists squirm. (Source: NYT)

Dysport Takes On Botox With Aggressive Rebates

NYT > Health — Fri, 12 Mar 2010 05:20:29 +0100

Medicis has started a new marketing campaign that pits its wrinkle-smoother, Dysport, directly against Botox. It makes bioethicists squirm. (Source: NYT > Health)

FDA Approves Botox for Muscle Spasms

Medscape Today Headlines — Wed, 10 Mar 2010 17:09:12 +0100

The FDA has approved a new indication for onabotulinumtoxin A injection for spasticity in the flexor muscles of the elbow, wrist, and fingers for adults. Medscape Medical News (Source: Medscape Today Headlines)

FDA Approves Botox for Spasticity

Medscape Business of Medicine Headlines — Wed, 10 Mar 2010 16:42:13 +0100

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FDA Approves Botox for Upper Limb Spasticity

Medscape Business of Medicine Headlines — Wed, 10 Mar 2010 16:42:13 +0100

Botulinum Toxin Okayed for Arm Spasms

MedPage Today Product Alert — Wed, 10 Mar 2010 16:15:17 +0100

WASHINGTON (MedPage Today) -- The FDA has approved a new indication for botulinum toxin type A (Botox) as a flexor muscle spasm treatment for the elbow, wrist, and fingers in adult patients. (Source: MedPage Today Product Alert)

FDA Okays Botox Use in Elbow, Wrist, Muscle Spasms

MedPage Today Product Alert — Wed, 10 Mar 2010 16:15:17 +0100

WASHINGTON (MedPage Today) -- The FDA has approved a new indication for onabotulinumtoxin A (Botox) as a flexor muscle spasm treatment for the elbow, wrist, and fingers in adult patients. (Source: MedPage Today Product Alert)

FDA Approves Botox to Treat Spasticity in Flexor Muscles of the Elbow, Wrist and Fingers

MedlinePlus Health News — Wed, 10 Mar 2010 15:47:23 +0100

Source: Food and Drug Administration Related MedlinePlus Pages: Botox, Neuromuscular Disorders, Wrist Injuries and Disorders (Source: MedlinePlus Health News)

Botox Approved to Treat Spasticity of Arm Muscles

Physician's First Watch current issue — Wed, 10 Mar 2010 13:31:32 +0100

(Source: Physician's First Watch current issue)

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Botox (onabotulinumtoxinA) Receives FDA Approval for Treatment of Upper Limb Spasticity in Adults

Drugs.com - New Drug Approvals — Wed, 10 Mar 2010 12:02:14 +0100

IRVINE, Calif.--(BUSINESS WIRE)--Mar 10, 2010 - Allergan, Inc. today announced that the United States Food and Drug Administration (FDA) has approved Botox (onabotulinumtoxinA) for the treatment of increased muscle stiffness in the elbow, wrist... (Source: Drugs.com - New Drug Approvals)

FDA Approves Botox To Treat Spasticity In Flexor Muscles Of The Elbow, Wrist And Fingers

Health News from Medical News Today — Wed, 10 Mar 2010 12:00:00 +0100

The U.S. Food and Drug Administration approved Botox (onabotulinumtoxin A) to treat spasticity in the flexor muscles of the elbow, wrist, and fingers in adults. Spasticity is common after stroke, traumatic brain injury, or the progression of multiple sclerosis. "Muscles affected by spasticity have increased stiffness and tightness, which may lead to pain, difficulties with hygiene and other activities of daily living, and may affect how a patient looks," said Russell Katz, M.D., director of the Division of Neurology Products in the FDA's Center for Drug Evaluation and Research... (Source: Health News from Medical News Today)

FDA Approves Botox To Treat Spasticity In Flexor Muscles Of The Elbow, Wrist And Fingers

Cosmetic Medicine / Plastic Surgery News From Medical News Today — Wed, 10 Mar 2010 12:00:00 +0100

Botox Approved for Spasticity in Stroke Victims

MedicineNet Cholesterol General — Wed, 10 Mar 2010 07:00:00 +0100

Title: Botox Approved for Spasticity in Stroke VictimsCategory: Health NewsCreated: 3/9/2010 6:10:00 PMLast Editorial Review: 3/10/2010 (Source: MedicineNet Cholesterol General)

Botox Approved for Spasticity in Stroke Victims

MedicineNet Heart General — Wed, 10 Mar 2010 07:00:00 +0100

Title: Botox Approved for Spasticity in Stroke VictimsCategory: Health NewsCreated: 3/9/2010 6:10:00 PMLast Editorial Review: 3/10/2010 (Source: MedicineNet Heart General)

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Botox Approved for Spasticity in Stroke Victims

MedicineNet Hepatitis C General — Wed, 10 Mar 2010 07:00:00 +0100

Title: Botox Approved for Spasticity in Stroke VictimsCategory: Health NewsCreated: 3/9/2010 6:10:00 PMLast Editorial Review: 3/10/2010 (Source: MedicineNet Hepatitis C General)

F.D.A. Extends Use of Botox in Treating Spasms

NYT — Wed, 10 Mar 2010 04:58:56 +0100

The drug, known for its ability to smooth frown lines, can now be used to treat spasticity in muscles of the elbow, wrist and fingers. (Source: NYT)

US FDA approves Botox to treat spasticity in flexor muscles of the elbow, wrist and fingers

NeLM - News — Wed, 10 Mar 2010 00:00:00 +0100

Source: FDA Area: News The US Food and Drug Administration has announced the approval of onabotulinumtoxin A (Botox®) to treat spasticity in the flexor muscles of the elbow, wrist, and fingers in adults. (Source: NeLM - News)

FDA approves Botox to treat wrist, finger spasms

Reuters: Health — Tue, 09 Mar 2010 22:39:05 +0100

CHICAGO (Reuters) - U.S. regulators on Tuesday approved the use of Allergan Inc's wrinkle smoother Botox to treat spasms of the elbow, wrist and fingers in adults. (Source: Reuters: Health)

FDA Approves Botox to Treat Wrist, Finger Spasms

MedlinePlus Health News — Tue, 09 Mar 2010 22:39:05 +0100

U.S. regulators on Tuesday approved the use of Allergan Inc's wrinkle smoother Botox to treat spasms of the elbow, wrist and fingers in adults.Source: Reuters Health Related MedlinePlus Pages: Botox, Muscle Disorders (Source: MedlinePlus Health News)

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FDA Approves Botox to Treat Spasticity in Flexor Muscles of the Elbow, Wrist and Fingers

Food and Drug Administration — Tue, 09 Mar 2010 21:42:00 +0100

The U.S. Food and Drug Administration today approved Botox (onabotulinumtoxin A) to treat spasticity in the flexor muscles of the elbow, wrist, and fingers in adults. Spasticity is common after stroke, traumatic brain injury, or the progression of multiple sclerosis. (Source: Food and Drug Administration)

Recession May Mean Fewer Nips & Tucks

MedlinePlus Health News — Tue, 09 Mar 2010 21:00:00 +0100

Breast augmentation, Botox still popular, but plastics surgeons' group cites 2% decline Source: HealthDay Related MedlinePlus Page: Plastic and Cosmetic Surgery (Source: MedlinePlus Health News)

Botox Approved for Spasticity in Stroke Victims

Modern Medicine — Tue, 09 Mar 2010 00:00:00 +0100

(Source: Modern Medicine)

Botox receives FDA approval for treatment of upper limb spasticity in adults

Multiple Sclerosis Trust — Tue, 09 Mar 2010 00:00:00 +0100

Allergan Inc announced that the United States Food and Drug Administration or FDA has approved Botox for treatment of increased muscle stiffness in the elbow, wrist and fingers in adults with upper limb spasticity. (Source: Multiple Sclerosis Trust)

Botulinum toxin injections for new onset bilateral vocal fold motion impairment in adults

The Laryngoscope — Mon, 08 Mar 2010 00:00:00 +0100

Review of clinical experience and results using botulinum toxin type A (BTX) for the management of adult patients with respiratory compromise due to new onset bilateral vocal fold motion impairment (BVFMI).Retrospective case series.The records of 11 patients from two institutions with respiratory compromise due to bilateral vocal fold motion impairment were reviewed. Age, sex, etiology of motion impairment, subjective response to BTX injections, changes in pulmonary function studies pre- and postinjection when available, the dosage of botulinum toxin required to achieve response, the number of injections per patient, and complications were reported.All patients were over 18 years old. There were three male and eight female subjects. The etiology of BVFMI was due to previous anterior cervic...

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Botox may help alleviate certain types of migraine pain

MedWire News - Dermatology — Fri, 05 Mar 2010 00:00:00 +0100

Botulinum toxin type A injections of cosmetic doses have the potential to alleviate symptoms of imploding and ocular migraines, report researchers. (Source: MedWire News - Dermatology)

Use of Botulinum Toxin Type A Injection for Neuropathic Pain after Trigeminal Nerve Injury

Pain Medicine — Thu, 04 Mar 2010 00:00:00 +0100

Conclusions. This case report suggests an effective new modality for treating neuropathic pain after trigeminal nerve injury. A further randomized controlled study involving a large number of patients is needed. (Source: Pain Medicine)

Predicting migraine responsiveness to botulinum toxin type A injections

NHS Evidence - Neurological conditions - News — Tue, 02 Mar 2010 15:12:18 +0100

(Source: NHS Evidence - Neurological conditions - News)

Single CT-Guided Chemodenervation of the Anterior Scalene Muscle with Botulinum Toxin for Neurogenic Thoracic Outlet Syndrome

Pain Medicine — Mon, 01 Mar 2010 00:00:00 +0100

Conclusion. Patients experienced substantial pain relief in months 1 and 2 following a single Botox injection into the ASM under CT guidance. Significant pain reduction was noted for 3 months after Botox injection with respect to both sensory and VAS scores, and the total and PPI scores approximated statistical significance. After 3 months, patients experienced a 29% decrease in the sensory component of their pain as well as an approximate 15% reduction in their VAS score. A single, CT-guided Botox injection into the ASM may offer an effective, minimally invasive treatment for NTOS. (Source: Pain Medicine)

Neurogenic temporomandibular joint dislocation treated with botulinum toxin: report of 4 cases

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Mon, 01 Mar 2010 00:00:00 +0100

In conclusion, the injection of botulinum toxin type A is an effective method in cases of neurogenic TMJ dislocation, with low morbididty and side effects, improving patients' quality of life. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

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Injection of botulinum toxin type A (BOTOX) into trigger zone of trigeminal neuralgia as a means to control pain

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Mon, 01 Mar 2010 00:00:00 +0100

This article illustrates a case of persistent trigeminal neuralgia in a medically compromised 65-year-old female who did not respond to pharmacotherapy. She had undergone several peripheral neurectomies as well as a failed right posterior fossa exploration that resulted in a cerebrospinal fluid leak. Persistent pain over the right external nasal area and right mental region was relieved for several hours after daily injections of bupivacaine. A trial of a single dose of 100 units of botulinum toxin type A (BOTOX) diluted in 2.5 mL saline was injected into the external nasal trigger zone (60 units) and to the mental nerve region (40 units). She achieved complete pain relief in the external nasal region for 5 months. Pain recurred and the site was again injected with 100 units of botulinum t...

[Effects of botulinum toxin type A in the single and repeated treatment of overactive bladder : A prospective analysis.]

Der Urologe. Ausg. A — Fri, 26 Feb 2010 00:00:00 +0100

CONCLUSION: The results of our prospective study show that the endoscopic application of BTX-A is a safe and highly effective treatment option for patients with OAB refractory to conventional treatment. PMID: 20182692 [PubMed - as supplied by publisher] (Source: Der Urologe. Ausg. A)

Should Botox Users Switch to Dysport and Save Money

Disabled World — Thu, 25 Feb 2010 17:10:13 +0100

Dysport: Should Botox Users Switch and Save Money? CosmeticSurgeryGuru Investigates - Similar to Botox, Dysport is a botulinum toxin Type A injection for eliminating fine lines and wrinkles. It costs 20% less than Botox, despite needing two extra treatments. (Source: Disabled World)

Botulinum Toxin Type A for Chronic Migraine

Current Neurology and Neuroscience Reports — Wed, 24 Feb 2010 06:55:48 +0100

Abstract Chronic migraine (CM) is the leading cause of chronic daily headache, a common and debilitating headache syndrome. The management of CM patients is challenging, with only limited benefit from available oral preventive medications. Botulinum neurotoxin (BoNT) has been used extensively to treat disorders associated with increased muscle tone. More recent scientific data support an analgesic effect of the toxin. The pharmacokinetic and pharmacodynamic profiles of BoNT make it an appealing candidate for migraine prevention. Results from older clinical trials on the efficacy of the toxin in CM were inconclusive. However, recent trials using more stringent inclusion criteria have shown positive results, supporting the use of the toxin in some patients with this disorder...

Ultrasound-Guided Botox Injections of Salivary Glands in Children with Drooling

Journal of Radiology Nursing — Mon, 22 Feb 2010 15:52:00 +0100

This study aimed to test the hypothesis that ultrasound-guided botox injection of the salivary glands in children is effective temporary palliation for excessive drooling. The study population consisted of 6 patients who underwent botox injection of salivary glands one or more times at a mid-Atlantic regional children's hospital. Parents were interviewed by telephone regarding the effects of the botox procedure on their child's drooling. The children who comprised our study population exhibited decreased drooling, less respiratory distress, and increased quality of life after the injections. Further research with a larger sample is warranted to support these findings. (Source: Journal of Radiology Nursing)

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Assurance scheme for botox clinics

Nursing in Practice — Mon, 22 Feb 2010 15:15:11 +0100

A new scheme will enable people considering botox and other facial treatments to check the reputation of their clinic (Source: Nursing in Practice)

Botox provider regulation plan announced

Nursing Times Breaking News — Sat, 20 Feb 2010 07:00:00 +0100

A registration scheme is to be set up for practitioners and organisations that provide injectable cosmetic treatments, such as Botox, for the first time. (Source: Nursing Times Breaking News)

Cosmetic jab clampdown criticised

BBC News | Health | UK Edition — Fri, 19 Feb 2010 12:32:55 +0100

An initiative to boost the safety of cosmetic treatments such as Botox does not go far enough, say surgeons. (Source: BBC News | Health | UK Edition)

Botox Smoothes Out Migraines

Medical Headlines From Ivanhoe.com — Thu, 18 Feb 2010 05:00:00 +0100

(Ivanhoe Newswire) -- New research brings good news for migraine sufferers: The same type of botulinum injection used for cosmetic purposes may be associated with reduced frequency of migraine headaches. (Source: Medical Headlines From Ivanhoe.com)

Botulinum toxin type A versus phenol. A clinical and neurophysiological study in the treatment of ankle clonus.

European Journal of Physical and Rehabilitation Medicine — Thu, 18 Feb 2010 00:00:00 +0100

CONCLUSIONS: While both treatments led to reduction in ankle clonus, phenol showed greater clinical efficacy. The difference in the neurophysiological results suggests that the two drugs have different action mechanisms with a more prevalent reduction of alpha motoneuron excitability in phenol-treated patients. PMID: 20168277 [PubMed - as supplied by publisher] (Source: European Journal of Physical and Rehabilitation Medicine)

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Botox may help some with migraines

Health News - UPI.com — Wed, 17 Feb 2010 19:16:38 +0100

ENCINCO, Calif., Feb. 17 (UPI) -- Botox injections used for cosmetic purposes may be associated with reduced frequency of some migraine headaches, U.S. researchers suggest. (Source: Health News - UPI.com)

Botox May Prevent Some Migraines

MedicineNet Skin General — Tue, 16 Feb 2010 07:00:00 +0100

Title: Botox May Prevent Some MigrainesCategory: Health NewsCreated: 2/15/2010 4:10:00 PMLast Editorial Review: 2/16/2010 (Source: MedicineNet Skin General)

Botox May Prevent Some Migraines

MedicineNet Senior Health General — Tue, 16 Feb 2010 07:00:00 +0100

Title: Botox May Prevent Some MigrainesCategory: Health NewsCreated: 2/15/2010 4:10:00 PMLast Editorial Review: 2/16/2010 (Source: MedicineNet Senior Health General)

Botox May Prevent Some Migraines

MedicineNet Hepatitis C General — Tue, 16 Feb 2010 07:00:00 +0100

Title: Botox May Prevent Some MigrainesCategory: Health NewsCreated: 2/15/2010 4:10:00 PMLast Editorial Review: 2/16/2010 (Source: MedicineNet Hepatitis C General)

Botox May Prevent Some Migraines

MedicineNet Migraine General — Tue, 16 Feb 2010 07:00:00 +0100

Title: Botox May Prevent Some MigrainesCategory: Health NewsCreated: 2/15/2010 4:10:00 PMLast Editorial Review: 2/16/2010 (Source: MedicineNet Migraine General)

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Botox Injections Found to Reduce Migraine Frequency

Modern Medicine — Tue, 16 Feb 2010 00:00:00 +0100

Migraineurs who received botulinum toxin type A injections have substantially decreased frequency of migraine headaches, but the relief is highly dependent on the type of migraine, according to a study in the February issue of the Archives of Dermatology. (Source: Modern Medicine)

Predicting Migraine Responsiveness to Botulinum Toxin Type A Injections [Observation]

Archives of Dermatology — Mon, 15 Feb 2010 20:50:42 +0100

Conclusions Our study supports the hypothesis that patients with imploding and ocular migraines are more responsive to BTX than those with exploding migraines. Injections of BTX at doses appropriate for cosmetic purposes may be sufficient to prevent migraine attacks. (Source: Archives of Dermatology)

Botox May Have Migraine Potential (CME/CE)

MedPage Today Pain Management — Mon, 15 Feb 2010 20:00:00 +0100

Botulinum toxin type A (Botox) provided significant relief from certain types of migraine in a small clinical study of migraine patients undergoing cosmetic procedures of the upper face. (Source: MedPage Today Pain Management)

Evaluation and treatment of synkinesis with botulinum toxin following facial nerve palsy.

Disability and Rehabilitation — Mon, 15 Feb 2010 00:00:00 +0100

Conclusions. BTX-A injection treatment was effective in reducing facial synkinesis, thus improving facial expression symmetry both at rest and in voluntary movements. PMID: 20156046 [PubMed - as supplied by publisher] (Source: Disability and Rehabilitation)

Thickened saliva after effective management of drooling with botulinum toxin A

Developmental Medicine and Child Neurology — Fri, 12 Feb 2010 00:00:00 +0100

Aim The aim of this study was to evaluate the rheological properties of saliva after submandibular botulinum toxin type A (BoNT-A) injections.Method We enrolled 15 children (11 males and six females; age range 3[ndash]17y, mean age 9y 10mo) diagnosed with spastic (n=9) or dyskinetic (n=6) quadriplegic cerebral palsy (CP); Gross Motor Function Classification System level IV or V; and two children with intellectual disability (IQ (Source: Developmental Medicine and Child Neurology)

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Forget the Botox! New iPhone app 'zaps acne and wrinkles' with red and blue lights

the Mail online | Health — Tue, 09 Feb 2010 02:15:25 +0100

Dr Greg Pearson’s AcneApp uses 420 nanometer blue light and 550 nanometer red light to help kill bacteria and promote collagen growth. (Source: the Mail online | Health)

Under the microscope: Marie Helvin on her secret alternative to Botox

the Mail online | Health — Tue, 09 Feb 2010 00:18:51 +0100

In this week's health quiz, the model and author, 57, talks pills, depression and her fear of falling flat on her face. (Source: the Mail online | Health)

Comparing Botox((R)) and Xeomin ((R)) for axillar hyperhidrosis.

Pain Physician — Tue, 09 Feb 2010 00:00:00 +0100

We report the first use of Xeomin((R)) in an autonomic indication. A total of 46 patients (34 females, 12 males, age 32.7 +/- 13.2 years, disease duration 14.2 +/- 12.0 years) with symmetric bilateral idiopathic axillar hyperhidrosis and a previously stable Botox((R)) treatment received 50 MU of BT in 5 ml of 0.9% NaCl/H(2)0 in each axilla. The patient, the injector and the observer were unaware of which axilla received Xeomin((R)) and which Botox((R)). The therapeutic effect as measured from the BT application to the onset of its decrease lasted 3.2 +/- 1.4 months and was excellent in 89% and good in 11% of the patients. Side-to-side differences of the therapeutic effect (onset latency, extent, duration) were neither detectable by the patient nor by the physician. Injection site pain was ...

Spring Botox Clinic

Women Speak — Mon, 08 Feb 2010 17:02:00 +0100

If you want real, noticeable results, discover what so many women have experienced - proven results with no surgery, no recovery time. Read more... (Source: Women Speak)

Spring Botox Clinic

Women Speak — Mon, 08 Feb 2010 17:02:00 +0100

If you want real, noticeable results, discover what so many women have experienced - proven results with no surgery, no recovery time. Read more... (Source: Women Speak)

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AAPM: Botox May Relieve Postherpetic Neuralgia (CME/CE)

MedPage Today Pain Management — Mon, 08 Feb 2010 12:13:10 +0100

SAN ANTONIO (MedPage Today) -- Subcutaneous injection of botulinum toxin A (Botox) significantly reduced postherpetic neuralgia compared with lidocaine and saline placebo in a small randomized clinical study. (Source: MedPage Today Pain Management)

N.Y. Botox banks to begin Monday

Health News - UPI.com — Sun, 07 Feb 2010 19:00:14 +0100

NEW YORK, Feb. 7 (UPI) -- A New York physician said Monday he will launch an online discount Botox bank that he hopes will spread into branches nationwide. (Source: Health News - UPI.com)

Allergan sees 51% jump in 4Q profits

bizjournals.com Health Care:Biotechnology headlines — Thu, 04 Feb 2010 19:19:10 +0100

Allergan Inc., the pharmaceutical company responsible for Botox, posted a 51 percent jump in fourth-quarter profits, fueled by higher sales of beauty products and medical devices. (AGN) (Source: bizjournals.com Health Care:Biotechnology headlines)

Facial Expressions And The Way We Feel And Understand

Health News from Medical News Today — Mon, 01 Feb 2010 09:00:00 +0100

Your facial expression may tell the world what you are thinking or feeling. But it also affects your ability to understand written language related to emotions, according to research that was presented to the Society for Personal and Social Psychology in Las Vegas, and will be published in the journal Psychological Science. The new study reported on 40 people who were treated with botulinum toxin, or Botox. Tiny applications of this powerful nerve poison were used to deactivate muscles in the forehead that cause frowning... (Source: Health News from Medical News Today)

Botox Therapy for Ischemic Digits

Journal of Vascular Surgery — Mon, 01 Feb 2010 00:00:00 +0100

Conclusion: Botox appears to provide improvement in digital perfusion and pain reduction in patients with Raynaud's syndrome when conservative management fails. Summary: Digital ulceration associated with Raynaud's syndrome is painful, difficult to treat, and frequently results in patient debilitation and chronic depression. Reports by Sycha and Van Beek have indicated potential benefit for patients with ischemic digits with local injection of botulinum toxin (Euro J Clin Invest 2004;34:312-3; Plast Reconstr Surg 2007;119:217-26). This was a retrospective observational study on outcomes of 19 patients with Raynaud's syndrome treated with botulinum toxin. All patients had chronic ischemic hand pain, and vascular studies had ruled out proximal occlusive disease and underlying disorders, inc...

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Botox Facial Slimming/Facial Sculpting: The Role of Botulinum Toxin-A in the Treatment of Hypertrophic Masseteric Muscle and Parotid Enlargement to Narrow the Lower Facial Width

Facial Plastic Surgery Clinics of North America — Mon, 01 Feb 2010 00:00:00 +0100

Botulinum toxin A is a highly efficacious and cost-effective, nonsurgical option for reducing the width and shape of the lower face and jawline. The results can vary from the subtlest thinning of the face to an extremely thin, cachectic appearance. Many nuances can be achieved. The administration is simple, and the process takes barely 5 minutes in an office setting. Botulinum toxin A can also be effectively used to reduce the bulk of an enlarged parotid gland without affecting saliva production. (Source: Facial Plastic Surgery Clinics of North America)

Botulinum toxin type A reduces pain supersensitivity in experimental diabetic neuropathy: Bilateral effect after unilateral injection.

European Journal of Pharmacology — Sat, 30 Jan 2010 00:00:00 +0100

Authors: Bach-Rojecky L, Salković-Petrišić M, Lacković Z We investigated antinociceptive activity of botulinum toxin type A (BTX-A) in a model of diabetic neuropathic pain in rats. Male Wistar rats were made diabetic by a single intraperitoneal injection of streptozotocin (80mg/kg). Sensitivity to mechanical and thermal stimuli was measured with the paw-pressure and hot-plate test, respectively. The formalin test was used to measure sensitivity to chemical stimuli. Diabetic animals with pain thresholds lower for at least 25% compared to the non-diabetic group were considered neuropathic and were injected with BTX-A either subcutaneously (3, 5 and 7U/kg) or intrathecally (1U/kg). Mechanical and thermal sensitivity was measured at several time-points. After periph...

Doctors Feel 'Choosing To Be Thinner In 2010 Could Be Bad For Your Health'

Health News from Medical News Today — Fri, 29 Jan 2010 05:00:00 +0100

Doctors are worried that as the New Year begins, many Americans will resolve to be thinner in 2010 by using over-the-counter supplements. According to a survey conducted by ADSAM and SenseUS polling companies, about 60 percent of physicians feel troubled about the safety of taking diet pills. Not surprisingly, while physicians feel negatively about the safety of over-the-counter diet pills, they are much more comfortable about the use of injections like Botox and Restylane or even breast implants... (Source: Health News from Medical News Today)

Quintastic: 50 is the new 30

Telegraph Health — Wed, 27 Jan 2010 16:11:25 +0100

2010 is the year of the Quintastics, women who discover that turning 50 brings with it a ferocious second wind. (Source: Telegraph Health)

BOTOX (Onabotulinumtoxina) Injection, Powder, Lyophilized, For Solution [Allergan, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 27 Jan 2010 05:00:00 +0100

Updated Date: Jan 27, 2010 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Prolonged vastus lateralis denervation after botulinum toxin type a injection

Movement Disorders — Wed, 27 Jan 2010 00:00:00 +0100

We present evidence of prolonged denervation following BoNT injection of the vastus lateralis (VL) muscle to correct quadriceps muscle imbalance in patients with chronic anterior knee pain. Needle electromyography data were obtained from 10 subjects who had received a single BoNT treatment 5 to 19 months earlier as part of a clinical trial. Insertional and spontaneous activity, recruitment, and motor unit action potentials were examined. Clear differences between the injected and non-injected VL muscles, which correlated with the time since injection, were identified in all subjects. All 10 subjects studied with needle EMG showed evidence of persisting denervation in the BoNT-A injected VL muscle beyond the period of neuromotor recovery expected from animal experimental studies. © 2010 Mo...

AAN Evaluates Cerebral Palsy Treatments for Kids

Disabled World — Tue, 26 Jan 2010 17:01:13 +0100

AAN Guideline Evaluates Treatments For Kids With Cerebral Palsy

Health News from Medical News Today — Tue, 26 Jan 2010 09:00:00 +0100

A new guideline from the American Academy of Neurology and the Child Neurology Society finds botulinum toxin type A to be an effective treatment for spasticity, muscle tightness that interferes with movement, in children and adolescents with cerebral palsy, but poses some risk. The guideline is published in the January 26, 2010, issue of Neurology®, the medical journal of the American Academy of Neurology. "Spasticity in children with cerebral palsy is best treated by a multidisciplinary medical and surgical team," said lead guideline author Mauricio R... (Source: Health News from Medical News Today)

AAN Guideline Evaluates Treatments For Kids With Cerebral Palsy

Pediatrics News From Medical News Today — Tue, 26 Jan 2010 09:00:00 +0100

New Guidelines Suggest Botox for Cerebral Palsy

MedicineNet Hepatitis C General — Tue, 26 Jan 2010 07:00:00 +0100

Title: New Guidelines Suggest Botox for Cerebral PalsyCategory: Health NewsCreated: 1/25/2010 4:10:00 PMLast Editorial Review: 1/26/2010 (Source: MedicineNet Hepatitis C General)

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Botox Found Effective for Children With Cerebral Palsy

Modern Medicine — Tue, 26 Jan 2010 00:00:00 +0100

Botulinum toxin is a safe and effective treatment for localized spasticity in children with cerebral palsy, according to a review in the Jan. 26 issue of Neurology. (Source: Modern Medicine)

Practice Parameter: Pharmacologic treatment of spasticity in children and adolescents with cerebral palsy (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society

Neurology — Mon, 25 Jan 2010 21:04:05 +0100

Objective: To evaluate published evidence of efficacy and safety of pharmacologic treatments for childhood spasticity due to cerebral palsy. Methods: A multidisciplinary panel systematically reviewed relevant literature from 1966 to July 2008. Results: For localized/segmental spasticity, botulinum toxin type A is established as an effective treatment to reduce spasticity in the upper and lower extremities. There is conflicting evidence regarding functional improvement. Botulinum toxin type A was found to be generally safe in children with cerebral palsy; however, the Food and Drug Administration is presently investigating isolated cases of generalized weakness resulting in poor outcomes. No studies that met criteria are available on the use of phenol, alcohol, or botulinum toxin type B inj...

New Guidelines Suggest Botox for Cerebral Palsy

MedlinePlus Health News — Mon, 25 Jan 2010 21:00:00 +0100

Drug injections can reduce muscle spasticity, experts say Source: HealthDay Related MedlinePlus Topics: Botox, Cerebral Palsy (Source: MedlinePlus Health News)

AAN guideline evaluates treatments for kids with cerebral palsy

EurekAlert! - Social and Behavioral Science — Mon, 25 Jan 2010 05:00:00 +0100

(American Academy of Neurology) A new guideline from the American Academy of Neurology and the Child Neurology Society finds botulinum toxin type A to be an effective treatment for spasticity, muscle tightness that interferes with movement, in children and adolescents with cerebral palsy, but poses some risk. The guideline is published in the January 26, 2010, issue of Neurology, the medical journal of the American Academy of Neurology. (Source: EurekAlert! - Social and Behavioral Science)

U.S. Attorney New Release: Bellevue, Washington Salon Owner Sentenced in Connection with Unlicensed Cosmetic Treatments

Food and Drug Administration — Tue, 19 Jan 2010 17:47:00 +0100

According to testimony at trial and records filed in the case, FAITH HE used counterfeit Botox© and Restylane© on customers at her Bellevue beauty salon. FAITH HE was not a medical doctor licensed to use injectable treatments for wrinkle removal such as Botox and Restylane. (Source: Food and Drug Administration)

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U.S. Attorney New Release: Bellevue, Washington Salon Owner Sentenced in Connection with Unlicensed Cosmetic Treatments

Food and Drug Administration — Tue, 19 Jan 2010 17:20:00 +0100

Botox and Dysport: Is there a dose conversion ratio in dermatology and aesthetic medicine?

Journal of the American Academy of Dermatology — Fri, 15 Jan 2010 14:02:06 +0100

To the Editor: The use of botulinum neurotoxin A is the most frequent intervention in aesthetic medicine. Sales of the two main preparations—Botox (Allergan Inc, Irvine, CA) and Dysport (Ipsen Ltd, Slough, Berkshire, UK)—amounted to USD $1 billion in 2007, and the trend is still growing. (Source: Journal of the American Academy of Dermatology)

Four unrelated patients with lubs X-linked mental retardation syndrome and different Xq28 duplications

American Journal of Medical Genetics Part A — Fri, 15 Jan 2010 00:00:00 +0100

The Lubs X-linked mental retardation syndrome (MRXSL) is caused by small interstitial duplications at distal Xq28 including the MECP2 gene. Here we report on four novel male patients with MRXSL and different Xq28 duplications delineated by microarray-based chromosome analysis. All mothers were healthy carriers of the duplications. Consistent with an earlier report [Bauters et al. (2008); Genome Res 18: 847-858], the distal breakpoints of all four Xq28 duplications were located in regions containing low-copy repeats (LCRs; J, K, and L groups), which may facilitate chromosome breakage and reunion events. The proximal breakpoint regions did not contain known LCRs. Interestingly, we identified apparent recurrent breakage sites in the proximal and distal breakpoint regions. Two of the four pati...

Combined Botulinum Toxin Type A With Modified Constraint-Induced Movement Therapy for Chronic Stroke Patients With Upper Extremity Spasticity: A Randomized Controlled Study

Neurorehabilitation and Neural Repair — Wed, 13 Jan 2010 02:02:04 +0100

Conclusions. Combining BtxA and mCIMT is an effective and safe intervention for improving spasticity and motor function in chronic stroke patients. The results are promising enough to justify further studies. We recommend future research to address the likely need for including rehabilitation with BtxA to improve function in patients with poststroke spasticity. (Source: Neurorehabilitation and Neural Repair)

Outcome of prenatally diagnosed isolated clubfoot.

The Ultrasound Review of Obstetrics and Gynecology — Tue, 12 Jan 2010 00:00:00 +0100

CONCLUSIONS:: When counselling prenatal patients regarding sonographically diagnosed isolated clubfoot, it is important to convey that approximately 10% of individuals will have a normal foot or positional foot deformity requiring minimal treatment. Conversely, 10-13% of prenatally diagnosed cases of isolated clubfoot will have complex clubfoot postnatally, based on the finding of additional structural or neurodevelopmental abnormalities. Although this study did not identify an increased risk of fetal aneuploidy associated with isolated clubfoot, a review of the literature indicates a risk of 1.7-3.6% with predominance of sex chromosome aneuploidy. Copyright (c) 2010 ISUOG. Published by John Wiley & Sons, Ltd. PMID: 20069547 [PubMed - as supplied by publisher] (Source: The Ultrasou...

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DIY Plastic Surgery A Trend In North Texas

Sat, 09 Jan 2010 23:59:38 +0100

Just a week into the New Year and some doctors say they're seeing a growing trend with do-it-yourself plastic surgery! From skincare, to laser treatments, to even do-it-yourself Botox… instructions and products are available online. But doctors say while DIY procedures can be cheaper, they're also dangerous. (Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire)

Botulinum Toxin Type A for Upper Limb Spasticity After Stroke

Medscape Today Headlines — Wed, 06 Jan 2010 12:04:40 +0100

This article will review the pharmacology of botulinum toxin type A and its clinical efficacy when used to treat upper limb spasticity after stroke. Expert Review of Neurotherapeutics (Source: Medscape Today Headlines)

Xeomin 100 units (botulinum toxin type A) - Change to theraeputic indication

NeLM - SPC Changes — Mon, 04 Jan 2010 00:00:00 +0100

Source: eMC (electronic Medicines Compendium) Area: Other Library Updates > SPC Changes ??Main change is the addition of a new indication for the symptomatic treatment of post-stroke spacsticity of the upper limb presenting with flexed wrist and clenched fist in adults. This change is reflected in sections: 4.1; 4.2; 4.4; 4.8 and 5.1. Other updates not related to the new indication include:- Section 4.4 Special Warnings & Precautions for use: addition of dyphagia Section 4.8 Undesirable effects: localised effects; addition of dysphagia, angle closure glaucoma, seizures, hypersensitivity and other generalised Botulinum toxins. (Source: NeLM - SPC Changes)

Experience with Injections of Botulinum Toxin Type A into the Detrusor Muscle.

Aktuelle Urologie — Fri, 01 Jan 2010 00:00:00 +0100

CONCLUSIONS: Injecting 300 units of BTX-A into 30 sites in the muscle located in the body of the bladder region is effective for neurogenic bladder patients with intermittent catheterization who have urge and reflective types of incontinence. Injec-tions of 100 and 200 units of BTX-A to treat non-neurogenic overactive bladder with urinary incontinence provided together without retention. The optimal dose of BTX-A requires further investigation. Injection with 200 units of BTX-A was not useful against interstitial cystitis. None of the patients developed any adverse effects after injecting the bladder wall with BTX-A. PMID: 20094947 [PubMed - as supplied by publisher] (Source: Aktuelle Urologie)

Botulinum Toxin Type A Reduces Histamine-induced Itch and Vasomotor Responses in Human Skin

Medscape Today Headlines — Tue, 29 Dec 2009 12:04:37 +0100

A clinical study has revealed that botulinum toxin type-A is effective against histamine-induced itch. The British Journal of Dermatology (Source: Medscape Today Headlines)

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Health news: Use oxygen to zap a headache and could Botox beat baldness?

the Mail online | Health — Tue, 29 Dec 2009 00:34:51 +0100

Inhaling oxygen could zap the agony of cluster headaches, according to research. Also could a jab of Botox in the scalp be a new way to treat some forms of baldness? (Source: the Mail online | Health)

Botox spared over tanning beds in health fight

Reuters: Health — Mon, 21 Dec 2009 21:33:49 +0100

WASHINGTON (Reuters) - In the rush to fund a U.S. healthcare overhaul, Botox injections to smooth wrinkles will not be taxed, but visiting a tanning salon will be. (Source: Reuters: Health)

An electrophysiological approach to the diagnosis of neurogenic dysphagia: implications for botulinum toxin treatment

Journal of Neurology, Neurosurgery & Psychiatry — Thu, 17 Dec 2009 18:07:51 +0100

Conclusions: This electrophysiological method can recognise swallowing abnormalities which may affect the outcome of the therapeutic approach to dysphagia with BTX treatment. (Source: Journal of Neurology, Neurosurgery & Psychiatry)

Got Handshake? The Silent Communicator

Psychology Today Work Center — Thu, 17 Dec 2009 17:48:21 +0100

It's stealth. It's power. And it's at your own fingertips. Forward to the office staff and print for the kids at home, for we have ten suggestions for handshakes done right. Pictures included! 1. Stand for handshakes. Unless you're physically unable or cannot move within the confines of space (at a booth in a restaurant, for instance), handshakes are offered and received in an upright stance. 2. Know the rules of handshake initiation. I'm frequently asked which gender should first extend their hand. In business situations, gender is irrelevant. What matters, however, is a person's organizational rank. Generally, a handshake should be offered by the person of higher authority to the person of lower status. Examples? The Director of HR extends to the job candidate, the dinn...

DYSPORT (Botulinum Toxin Type A) Injection, Powder, Lyophilized, For Solution [Tercica, Inc.]

DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST) — Wed, 16 Dec 2009 05:00:00 +0100

Updated Date: Dec 16, 2009 EST (Source: DailyMed Drug Label Updates for the last seven days (since May 20, 2007 EST))

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Prospective Randomized Evaluation of Periureteral Botulinum Toxin Type A Injection for Ureteral Stent Pain Reduction

The Journal of Urology — Wed, 16 Dec 2009 00:00:00 +0100

Conclusions: Periureteral botulinum toxin type A injection improves ureteral stent tolerability by significantly decreasing postoperative pain and narcotic requirements. Improvement in irritative symptoms was not observed. (Source: The Journal of Urology)

Botulinum Toxin Type A May Effectively Treat Stroke-Related Upper Limb Spasticity

Medscape Today Headlines — Tue, 15 Dec 2009 18:13:17 +0100

This review discusses the therapeutic use of botulinum toxin type A in upper limb spasticity. Medscape Neurology & Neurosurgery (Source: Medscape Today Headlines)

Pharma firms, surgeons battle 'Botax'

Modern Medicine — Fri, 11 Dec 2009 00:00:00 +0100

Irvine, Calif. ? Botox-maker Allergan, based here, has joined with cosmetic surgeons and other pharma firms to fight a proposed tax that would help fund healthcare reform, the Orange County (Calif.) Business Journal reports. (Source: Modern Medicine)

Can occlusal devices prolong the effect of botulinum toxin type A in the contouring of the lower face?

European Journal of Plastic Surgery — Thu, 10 Dec 2009 15:14:57 +0100

This study analyzes the efficacy of occlusal devices for the long-term stability of contouring of the lower face by injection of Botulinum toxin type A in a prospective clinical protocol. Ten patients (seven female and three male) with a widened lower face were recruited consecutively between January 2006 and January 2007. Each patient was advised to wear an occlusal device to release masticatory muscles, and percutaneous intramuscular injections of Botulinum toxin type A were used. The follow-up study was 18 months. Facial changes were noted by the patients as early as 2 weeks after the injection and lasted for 18 months; all patients reported an improved facial profile. There were no complications. Botulinum toxin type A injection for the contouring of the lower face...

Botox, facelifts may cost more as Senate eyes cosmetic surgery tax

USATODAY.com Health — Mon, 07 Dec 2009 19:31:30 +0100

The Senate debate on an $848 billion health care reform bill includes a 5% excise tax on elective cosmetic surgery, beginning ... (Source: USATODAY.com Health)

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Cosmetic Surgery Industry Lobbies Against The 'Botax' In Senate Health Bill

Health News from Medical News Today — Mon, 07 Dec 2009 08:00:00 +0100

"Leading makers of antiwrinkle drugs, breast implants and other appearance-related products are trying to derail a proposed tax on elective cosmetic surgery in the Senate's health-overhaul bill," The Wall Street Journal reports. "The proposed 5% levy -- dubbed the 'Botax' after the antiwrinkle treatment product Botox -- would raise an estimated $5.8 billion over 10 years." The tax proposal has raised the ire of the cosmetic surgery industry. "Two leading companies in aesthetic treatments, Allergan Inc. and Medicis Pharmaceutical Corp... (Source: Health News from Medical News Today)

Cosmetic Surgery Industry Lobbies Against The 'Botax' In Senate Health Bill

Cosmetic Medicine / Plastic Surgery News From Medical News Today — Mon, 07 Dec 2009 08:00:00 +0100

"Leading makers of antiwrinkle drugs, breast implants and other appearance-related products are trying to derail a proposed tax on elective cosmetic surgery in the Senate's health-overhaul bill," The Wall Street Journal reports. "The proposed 5% levy -- dubbed the 'Botax' after the antiwrinkle treatment product Botox -- would raise an estimated $5.8 billion over 10 years... (Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today)

Cosmetic Surgery Industry Lobbies Against The 'Botax' In Senate Health Bill

Cosmetic Medicine / Plastic Surgery News From Medical News Today — Mon, 07 Dec 2009 08:00:00 +0100

"Leading makers of antiwrinkle drugs, breast implants and other appearance-related products are trying to derail a proposed tax on elective cosmetic surgery in the Senate's health-overhaul bill," The Wall Street Journal reports. "The proposed 5% levy -- dubbed the 'Botax' after the antiwrinkle treatment product Botox -- would raise an estimated $5.8 billion over 10 years... (Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today)

Botulinum Toxin Type A for the Treatment of Glabellar Lines in Chinese: A Double-Blind, Randomized, Placebo-Controlled Study

Dermatologic Surgery — Mon, 07 Dec 2009 00:00:00 +0100

This is the first well-controlled study of the use of botulinum toxin type A (BoNTA) for glabellar lines in China. To evaluate the safety and efficacy of BoNTA in the treatment of glabellar lines in Chinese subjects. A total of 227 subjects received a single treatment in a 3:1 randomization ratio of BoNTA (20 U):placebo and were observed for 120 days after injection. Effective outcome measures included investigator's rating of wrinkle severity at maximum frown and rest and subjects' global assessment and self-perception of age. A significantly higher responder rate at maximum frown, ranging from 94.1% at day 30 to 52.9% at day 120, was noted in the BoNTA group. The proportion of subjects with none or mild glabellar lines at rest was 66.7% in the BoNTA group at day 30. Most (95.3%) of the s...

Grinding my teeth gave me a square jaw. Now I have the face I longed for - thanks to Botox

the Mail online | Health — Sun, 06 Dec 2009 01:18:07 +0100

From an early age Louisa Smith hated the rather masculine shape of her face. But she never guessed her looks were the result of a nervous habit. (Source: the Mail online | Health)

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Needle Preference in Patients Receiving Cosmetic Botulinum Toxin Type A

Dermatologic Surgery — Fri, 04 Dec 2009 00:00:00 +0100

This study sought to determine whether patients receiving BTX-A have a preference for 30-gauge or 32-gauge needles based on the amount of pain and bruising experienced. Thirty-seven subjects received BTX-A on the right side of the face using a 30-gauge needle and on the left side using a 32-gauge needle. Subjects were masked to needle size. They were then asked to rate injection pain on an 11-point numerical rating scale and to note any bruising. Physician preference was also evaluated. There were no statistically significant differences in the amount of intra-procedural pain (p=.37) or the level of post-procedural pain and discomfort (p=.76) experienced. Twenty-seven percent of subjects reported greater bruising with the 32-gauge needle, versus 29.7% with the 30-gauge needle. The physicia...

Botox 200 Units (botulinum toxin A) - New formulation

NeLM - SPC Changes — Fri, 04 Dec 2009 00:00:00 +0100

Source: Manufacturer notification Area: Other Library Updates > SPC Changes Botox now available as a 200U/vial preparation Refer to SPC for full details (Source: NeLM - SPC Changes)

Botox Delivered on Sponge Reduces Symptoms of Rhinitis

Skin and Allergy News — Tue, 01 Dec 2009 00:00:00 +0100

OnabotulinumtoxinA administered via a sponge inserted into the nasal cavity may reduce symptoms in some patients with refractory idiopathic rhinitis, according to a small German study. (Source: Skin and Allergy News)

Policy & Practice

Skin and Allergy News — Tue, 01 Dec 2009 00:00:00 +0100

Can't get enough Policy & Practice? Check out our new podcast each Monday. egmnblog.wordpress.com Allergan just reported its third-quarter earnings, and although Botox (onabotulinumtoxinA) sales increased a scant 3%, the company said that the injectable contributed to a net profit rise of 8.3%. The company predicted that its total Botox sales for the year would be almost $1.3 billion. Also in the third quarter, Allergan filed for Food and Drug Administration approval to promote the use of Botox for migraine headaches and submitted additional data to the agency on the drug's use for upper limb spasticity. Allergan also stated that it expects sales of the eyelash lengthener Latisse (bimatoprost) to hit $70 million for the year. (Source: Skin and Allergy News)

Microbiological and clinical profiles of patients with microbial keratitis residing in nursing homes

British Journal of Ophthalmology — Wed, 25 Nov 2009 18:06:25 +0100

Conclusions: Microbial keratitis in patients living in nursing homes is usually caused by Staphylococcus and is associated with dry eyes and ocular surface disease. Surgical intervention is required in majority of cases with poor visual outcome. (Source: British Journal of Ophthalmology)

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MUSC Holiday Botox Clinic

Women Speak — Tue, 24 Nov 2009 20:57:00 +0100

Look stress-free for the holidays and start the new year with a new, more youthful You. Treat yourself to the MUSC Holiday Botox Clinic and leave the scowling for the Grinch! Read more... (Source: Women Speak)

MUSC Holiday Botox Clinic

Women Speak — Tue, 24 Nov 2009 20:57:00 +0100

Electrical activation of the orbicularis oculi muscle does not increase the effectiveness of botulinum toxin type a in patients with blepharospasm

European Journal of Neurology — Tue, 24 Nov 2009 00:00:00 +0100

Conclusions: In patients with BPS, the electrically induced muscle activation neither increases the effectiveness of BonT-A nor produces larger electrophysiological peripheral effects. The lack of BonT-A-induced changes in the blink reflex recovery cycle provides evidence that BonT-A therapy is safe in patients with BPS. (Source: European Journal of Neurology)

Plastic Surgeons Cry Foul Over Senate Health Bill's Cosmetic Surgery Tax

Public Health News From Medical News Today — Sun, 22 Nov 2009 11:00:00 +0100

Kaiser Health News staff writer Phil Galewitz writes about the so-called "botax." "If you're considering Botox to erase frown lines or liposuction to get rid of love handles, you might want to move fast. ... The $848 billion health care bill unveiled Wednesday by Senate Majority Leader Harry Reid, D-Nev., includes a 5 percent tax on cosmetic procedures and surgeries" (11/19). (Source: Public Health News From Medical News Today)

Plastic Surgeons Cry Foul Over Senate Health Bill's Cosmetic Surgery Tax

Health News from Medical News Today — Sun, 22 Nov 2009 11:00:00 +0100

Kaiser Health News staff writer Phil Galewitz writes about the so-called "botax." "If you're considering Botox to erase frown lines or liposuction to get rid of love handles, you might want to move fast. ... The $848 billion health care bill unveiled Wednesday by Senate Majority Leader Harry Reid, D-Nev., includes a 5 percent tax on cosmetic procedures and surgeries" (11/19). Read entire story. (Source: Health News from Medical News Today)

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Plastic Surgeons Cry Foul Over Senate Health Bill's Cosmetic Surgery Tax

Cosmetic Medicine / Plastic Surgery News From Medical News Today — Sun, 22 Nov 2009 11:00:00 +0100

Kaiser Health News staff writer Phil Galewitz writes about the so-called "botax." "If you're considering Botox to erase frown lines or liposuction to get rid of love handles, you might want to move fast. ... The $848 billion health care bill unveiled Wednesday by Senate Majority Leader Harry Reid, D-Nev., includes a 5 percent tax on cosmetic procedures and surgeries" (11/19). Read entire story... (Source: Cosmetic Medicine / Plastic Surgery News From Medical News Today)

[Treatment of drooling with botulinum toxin type A in cerebral palsy.]

Revista de Neurologia — Sat, 21 Nov 2009 02:18:15 +0100

Authors: Duarte CS, Alves TR, Azeredo PM, Almeida SI PMID: 19921629 [PubMed - as supplied by publisher] (Source: Revista de Neurologia)

Treatment success for overactive bladder with urinary urge incontinence refractory to oral antimuscarinics: a review of published evidence

BioMed Central — Fri, 20 Nov 2009 00:00:00 +0100

Conclusions: A treatment success definition that encompasses the many components of underlying OAB with UUI symptoms is currently not practical as a consequence of difficulties in measuring urgency. The treatment success outcome of >=50% improvement in incontinence episodes was associated with a clinically meaningful improvement in disease-specific HRQoL for those with neurogenic OAB with UUI. The recommended success definition is less restrictive than a measure such as complete continence but includes patients who are satisfied with treatment and experience meaningful improvement in symptoms. A standardized measure of treatment success will be useful in clinical and health economic applications. (Source: BioMed Central)

Merz Pharmaceuticals Announces Approval Of Post-stroke Upper Limb Spasticity Indication For Xeomin(R) In The EU

Stroke / Neuroprotection News From Medical News Today — Thu, 19 Nov 2009 11:00:00 +0100

Merz Pharmaceuticals announced Xeomin®, the first botulinum toxin type A free from complexing proteins has been granted an extension of indication for post-stroke spasticity of the upper limb presenting with flexed wrist and clenched fist in adults in various European countries. Xeomin® was already granted approval for post-stroke spasticity of the upper limb in early 2009 in Canada, Mexico and Argentina. (Source: Stroke / Neuroprotection News From Medical News Today)

Merz Pharmaceuticals Announces Approval Of Post-stroke Upper Limb Spasticity Indication For Xeomin(R) In The EU

Health News from Medical News Today — Thu, 19 Nov 2009 11:00:00 +0100

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License extension for Xeomin® (botulinum toxin type A) in EU to include treatment of post-stroke upper limb spasticity

NeLM - News — Thu, 19 Nov 2009 00:00:00 +0100

Source: PharmaLive Area: News The license for Xeomin® (botulinum toxin type A) has been extended in the EU to include the management of post-stroke spasticity of the upper limb presenting with flexed wrist and clenched fist in adults. Xeomin® is already licensed for the symptomatic management of blepharospasm and cervical dystonia of a predominantly rotational form (spasmodic torticollis) in adults. The current license extension is based on the Kanovsky study, the largest randomised, placebo-controlled, double-blind trial with a botulinum toxin in upper limb post-stroke spasticity to date. (Source: NeLM - News)

Cosmetic surgery 'needs regulation'

NHS News Feed — Mon, 16 Nov 2009 17:44:00 +0100

Several newspapers have reported the dangers associated with cosmetic surgery, including a lack of regulation in some areas of the industry. The reports also feature warnings from Nigel Mercer, the president of the British Association of Aesthetic Plastic Surgeons, who voiced his views as part of a series of medical articles on cosmetic surgery. Mr Mercer called for tighter regulation and testing of drugs, procedures and implants to offer more protection to patients. The Times reported that the number of cosmetic surgical operations conducted by “audited members of the profession” has more than tripled to 34,000 since 2003, but that many additional procedures are being carried out illegally on the black market. The newspaper says that these are “fuelled by internet promotions, magazi...

Botox Takes A Shot At Pain

ScienceDaily Headlines — Tue, 10 Nov 2009 04:00:00 +0100

No longer just a wrinkle fighter, Botox may have indications as a pain medication to fight Chronic Regional Pain Syndrome (CRPS), according to a new study. (Source: ScienceDaily Headlines)

The Lowe Law Firm Files Suit Over Alleged Botox Overdose

Health News from Medical News Today — Mon, 09 Nov 2009 12:00:00 +0100

St. Louis-based The Lowe Law Firm has filed a lawsuit on behalf of a man who experienced partial respiratory paralysis and other side effects after receiving an overdose of the Botox being used to treat his muscle spasticity. The suit, Richard A. Hart v. Yi Pan, Tenet HealthSystem SL Inc., d/b/a St. Louis University Hospital and Allergan USA Inc., cause no. 0922-CC09485, was filed in St. (Source: Health News from Medical News Today)

The Lowe Law Firm Files Suit Over Alleged Botox Overdose

Cosmetic Medicine / Plastic Surgery News From Medical News Today — Mon, 09 Nov 2009 12:00:00 +0100

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The Lowe Law Firm Files Suit Over Alleged Botox Overdose

Cosmetic Medicine / Plastic Surgery News From Medical News Today — Mon, 09 Nov 2009 12:00:00 +0100

Botox gets a rival - but should you fall for the lure of Azzalure?

the Mail online | Health — Mon, 09 Nov 2009 11:17:22 +0100

A serious contender to the celebrities' favourite frown-freezer has been launched in the UK. (Source: the Mail online | Health)

Botox gets a rival - but should you fall for the lure of Azzalure?

the Mail online | Health — Sat, 07 Nov 2009 21:35:31 +0100

A serious contender to the celebrities' favourite frown-freezer has been launched in the UK. (Source: the Mail online | Health)

Botox for breasts: New treatment helps women lift sagging cleavage

the Mail online | Health — Fri, 06 Nov 2009 13:19:51 +0100

With the treatment taking just half an hour, it is proving popular with busy young mothers who don't have time to go under the knife. (Source: the Mail online | Health)

Botox May Reduce Frequency of Migraines

Skin and Allergy News — Sun, 01 Nov 2009 00:00:00 +0100

PHILADELPHIA — OnabotulinumtoxinA appears to be a safe, effective, and well-tolerated headache prophylactic for patients with chronic migraine. Two large randomized controlled trials showed that the toxin significantly reduced migraine frequency and improved headache-related disability over a 24- week period, Dr. David W. Dodick reported at the International Headache Congress. (Source: Skin and Allergy News)

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Policy & Practice: Can't get enough Policy & Practice? Check out our new podcast each Monday. egmnblog.wordpress.com

Skin and Allergy News — Sun, 01 Nov 2009 00:00:00 +0100

Allergan, the manufacturer of Botox (onabotulinumtoxinA), has sued the Food and Drug Administration, claiming that the agency's restrictions on off-label promotions are inhibiting the company's ability to “proactively share truthful and relevant information with the medical community,” according to a company statement. FDA's constraint that Allergan discuss off-label uses for Botox only in general terms violates the first amendment and hurts patients, Allergan claimed. To fully inform physicians, the company said it needs to describe dosing guidelines, patient selection criteria, and proper injection technique. “We believe that the inability to share such important information proactively with the medical community violates the First Amendment and potentially diminishes the quality o...

Botox May Reduce Frequency of Migraines

Internal Medicine News — Sun, 01 Nov 2009 00:00:00 +0100

PHILADELPHIA — OnabotulinumtoxinA appears to be a safe, effective, and well-tolerated headache prophylactic for patients with chronic migraine. Two large randomized, controlled trials showed that the toxin significantly reduced migraine frequency and improved headache-related disability over 24 weeks, Dr. David W. Dodick reported at the International Headache Congress. (Source: Internal Medicine News)

A double-blind comparison of onabotulinumtoxina (BOTOX) and topiramate (TOPAMAX) for the prophylactic treatment of chronic migraine: a pilot study.

Headache — Sun, 01 Nov 2009 00:00:00 +0100

CONCLUSIONS: OnabotulinumtoxinA and topiramate demonstrated similar efficacy in the prophylactic treatment of CM. Patients receiving onabotulinumtoxinA had fewer AEs and discontinuations. PMID: 19912346 [PubMed - in process] (Source: Headache)

Botulinum Toxin for the Correction of Asymmetric Crying Facies

Aesthetic Surgery Journal — Sun, 01 Nov 2009 00:00:00 +0100

The clinical hallmark of asymmetric crying facies (ACF) is a symmetric appearance of the oral aperture and lips at rest, but significant depression of one side of the lower lip with animation (crying or smiling). ACF can resolve spontaneously in the first year of life, but surgical intervention may be required at some point to ensure a good cosmetic outcome. The authors report on the successful use of botulinum toxin type A to achieve temporary facial symmetry in two children with ACF with results lasting up to six months and suggest that such treatments may be helpful in providing more time to consider and/or plan surgical intervention. (Source: Aesthetic Surgery Journal)

The use of botulinum toxin type A in urological procedures.

Urologic Nursing — Sun, 01 Nov 2009 00:00:00 +0100

This article will explore the use of Botox in urology and provide a brief review of the literature supporting its use. PMID: 20088238 [PubMed - in process] (Source: Urologic Nursing)

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Lower urinary tract dysfunction in MS: management in the community.

British Journal of Community Nursing — Sun, 01 Nov 2009 00:00:00 +0100

Authors: Panicker J, Haslam C Lower urinary tract dysfunction in multiple sclerosis is common and is highly amenable to treatment. Individuals may have bladder storage and/or voiding dysfunction. The risk of progression to renal failure is low and hence lower urinary tract dysfunction should be considered medically manageable in most individuals. Evaluation begins with history taking and is supplemented by using a bladder diary. Ultrasonography is used to assess the degree of incomplete bladder emptying, and for assessing upper urinary tract damage. Incomplete bladder emptying is most often managed by clean intermittent self-catheterization and should be initiated if post-void residual urine is greater than 100 mls. Storage symptoms are most often managed using antimuscarinic medicatio...

Treatment of congenital esotropia with botulinum toxin type A

Acta Ophthalmologica — Fri, 30 Oct 2009 00:00:00 +0100

Conclusion: Botulinum toxin type A injections into the medial recti muscles are a valuable alternative to conventional strabismus surgery. (Source: Acta Ophthalmologica)

Ipsen Announces the Launch of Dysport(R) (abobotulinumtoxinA) in the United States for the Treatment of Cervical Dystonia

HSMN NewsFeed — Thu, 29 Oct 2009 15:19:24 +0100

Dysport(R) represents the first new botulinum toxin type A treatment option in eight years to reach the U.S. market place PARIS--(HSMN NewsFeed)--Ipsen (Paris: IPN ), an innovation-driven global specialty pharmaceutical group, today announced that Dyspo... BiopharmaceuticalsIpsen, Dysport, abobotulinumtoxinA, cervical dystonia (Source: HSMN NewsFeed)

Allergan Wants Court To Find Off-Label Promotion Rules Are Unconstitutional

LexisNexis® Mealey's™ Arthritis Drugs Legal News — Thu, 29 Oct 2009 14:30:33 +0100

WASHINGTON, D.C. - Already under federal investigation for the off-label marketing of Botox, manufacturer Allergan Inc. on Oct. 1 asked a federal court to declare that federal regulations barring promotion of off-label uses of drugs are an unconstitutional violation of its First Amendment free speech rights (Allergan, Inc. v. United States of America, et al., No. 09-1879, D. D.C.). Full story on lexis.com (Source: LexisNexis® Mealey's™ Arthritis Drugs Legal News)

Botox as a Breast Lift?

MedicineNet Skin General — Tue, 27 Oct 2009 07:00:00 +0100

Title: Botox as a Breast Lift?Category: Health NewsCreated: 10/27/2009 10:02:00 AMLast Editorial Review: 10/27/2009 10:02:27 AM (Source: MedicineNet Skin General)

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Botox as a Breast Lift?

MedicineNet Senior Health General — Tue, 27 Oct 2009 07:00:00 +0100

Title: Botox as a Breast Lift?Category: Health NewsCreated: 10/27/2009 10:02:00 AMLast Editorial Review: 10/27/2009 10:02:27 AM (Source: MedicineNet Senior Health General)

Botox as a Breast Lift?

MedicineNet HIV General — Tue, 27 Oct 2009 07:00:00 +0100

Title: Botox as a Breast Lift?Category: Health NewsCreated: 10/27/2009 10:02:00 AMLast Editorial Review: 10/27/2009 10:02:27 AM (Source: MedicineNet HIV General)

Botox as a Breast Lift?

eMedicineHealth.com — Tue, 27 Oct 2009 07:00:00 +0100

(Source: eMedicineHealth.com)

Botox as a Breast Lift?

MedicineNet Womens Health General — Tue, 27 Oct 2009 07:00:00 +0100

Title: Botox as a Breast Lift?Category: Health NewsCreated: 10/27/2009 10:02:00 AMLast Editorial Review: 10/27/2009 10:02:27 AM (Source: MedicineNet Womens Health General)

Botox Fights Pain

Medical Headlines From Ivanhoe.com — Tue, 27 Oct 2009 05:00:00 +0100

Botox may have the power not only to remove wrinkles, but ease pain that's unresponsive to treatments like massage and heat/cold therapy. (Source: Medical Headlines From Ivanhoe.com)

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Botox as a Breast Lift?

WebMD Health — Tue, 27 Oct 2009 00:00:05 +0100

Add breast lifts to the growing list of potential uses for Botox. But not all experts think it's worth the trouble. (Source: WebMD Health)

Botox as a Breast Lift?

WebMD Health — Tue, 27 Oct 2009 00:00:05 +0100

Add breast lifts to the growing list of potential uses for Botox. But not all experts think it's worth the trouble. (Source: WebMD Health)

News From Plastic Surgery 2009

Health News from Medical News Today — Mon, 26 Oct 2009 11:00:00 +0100

Botox Takes a Shot at Pain No longer just a wrinkle fighter, Botox® may have indications as a pain medication to fight Chronic Regional Pain Syndrome (CRPS), reports a new study presented at the American Society of Plastic Surgeons (ASPS) Plastic Surgery 2009 conference, Oct. 23-27, in Seattle. (Source: Health News from Medical News Today)

Supraciliary wrinkles and botulinum toxin A

Clinical And Experimental Dermatology — Thu, 22 Oct 2009 23:00:00 +0100

Conclusions. Injection of botulinum toxin type A through the temporal hairline to correct supraciliary wrinkles seems to be safe and effective. (Source: Clinical And Experimental Dermatology)

What Is Dystonia?

About.com Bipolar Disorder — Mon, 19 Oct 2009 23:00:00 +0100

Dystonia is a rare neurological movement disorder characterized by involuntary muscle contractions, which force certain parts of the body into abnormal, sometimes painful, movements or postures. It can be inherited due to genetic abnormalities as seen in multiple sclerosis. It can also be caused by brain injuries, toxins and some medications. Antipsychotic medication, often prescribed in the treatment of bipolar disorder, is one class of drugs that can cause dystonia, which is one of several extrapyramidal side effects. Generally it is the first generation antipsychotics also known as typical antipyschotics that can cause these side effects. There is no cure for dystonia. However, there are a few options for treating the symptoms of the disorder. One of the most common treatments is Boto...

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Botox sponge may benefit some patients with idiopathic rhinitis

MedWire News - Respiratory — Mon, 19 Oct 2009 14:21:59 +0100

A nasally-inserted sponge that is soaked with botulinum toxin A provides a minimally invasive, effective alternative to botox injections for patients with treatment-resistant idiopathic rhinitis, research shows. (Source: MedWire News - Respiratory)

Botox sponge treats allergic runny nose

Health News - UPI.com — Fri, 16 Oct 2009 21:55:31 +0100

GOTTINGEN, Germany, Oct. 16 (UPI) -- Injecting botulinum toxin -- botox -- to treat intrinsic or allergic rhinitis, or runny nose, may be a thing of the past, German researchers said. (Source: Health News - UPI.com)

No Need For Needles: Botox Sponge Treats Intrinsic Rhinitis

ScienceDaily Headlines — Fri, 16 Oct 2009 21:00:00 +0100

Injecting botulinum toxin (botox) to treat intrinsic or allergic rhinitis may be a thing of the past as researchers have now shown that sponges soaked in botox are equally effective in treating the condition. The research offers a potential needle-free treatment to the millions of people who suffer from rhinitis. (Source: ScienceDaily Headlines)

Botox Sponge Treats Intrinsic Rhinitis Without Needles

Health News from Medical News Today — Fri, 16 Oct 2009 12:00:00 +0100

Injecting botulinum toxin (botox) to treat intrinsic or allergic rhinitis may be a thing of the past as researchers have now shown that sponges soaked in botox are equally effective in treating the condition. The research published in BioMed Central's open access journal Head & Face Medicine offers a potential needle-free treatment to the millions of people who suffer from rhinitis. (Source: Health News from Medical News Today)