MedWorm: Academies

Anti-Obesity Drug Now In Clinical Trials May Cause Rapid Bone Loss

Health News from Medical News Today — Thu, 09 Feb 2012 08:00:00 +0100

An endocrine hormone used in clinical trials as an anti-obesity and anti-diabetes drug causes significant and rapid bone loss in mice, raising concerns about its safe use, UT Southwestern Medical Center researchers have shown. The hormone, fibroblast growth factor 21 (FGF21), promotes bone loss by enhancing the activity of a protein that stimulates fat cells but inhibits bone cells, researchers report in a study available online in Proceedings of the National Academy of Sciences. "This hormone is a very potent regulator of bone mass," said Dr... (Source: Health News from Medical News Today)

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Researchers Pave The Way For Improving Treatment For Type 2 Diabetes

Health News from Medical News Today — Thu, 09 Feb 2012 08:00:00 +0100

In a study published last week in the prestigious Proceedings of the National Academy of Sciences of the United States of America, a team led by Dr. Vincent Poitout of the University of Montreal Hospital Research Centre (CRCHUM)* has made an important step forward in understanding how insulin secretion is regulated in the body. This discovery has important implications for drugs currently in development to treat Type 2 diabetes, a disease which is diagnosed every 10 seconds somewhere throughout the world... (Source: Health News from Medical News Today)

Knee Replacement May Lower A Patient's Risk For Mortality And Heart Failure

Health News from Medical News Today — Thu, 09 Feb 2012 08:00:00 +0100

New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) highlights the benefits of total knee replacement (TKR) in elderly patients with osteoarthritis, including a lower probability of heart failure and mortality. Investigators reviewed Medicare records to identify osteoarthritis patients, separating them into two groups - those who underwent TKR to relieve symptoms, and those who did not... (Source: Health News from Medical News Today)

Girls In Competitive Soccer At Increased Risk Of Injuries And Menstrual Dysfunction

Health News from Medical News Today — Thu, 09 Feb 2012 08:00:00 +0100

In the U.S., there are nearly three million youth soccer players, and half of them are female. New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS) found that despite reporting appropriate body perception and attitudes toward eating, elite youth soccer athletes (club level or higher) face an increased risk for delayed or irregular menstruation. In addition, female soccer players are more likely to suffer a stress fracture or ligament injury. A separate study found that a consistent 15-minute warm-up substantially decreases knee injury risk... (Source: Health News from Medical News Today)

Steep Learning Curve For Surgeons Who Perform ACL Reconstructions Identified By Study

Health News from Medical News Today — Thu, 09 Feb 2012 08:00:00 +0100

Patients who have their anterior cruciate ligament (ACL) reconstructed by surgeons who have performed less than 60 surgeries are roughly four to five times more likely to undergo a subsequent ACL reconstruction, according to a study by researchers at Hospital for Special Surgery. The study also showed that participating in a subspecialty orthopedic fellowship-training program did not improve the learning curve of young surgeons performing ACL reconstructions. The research was presented at the annual meeting of the American Academy of Orthopedic Surgeons, held Feb 7-11... (Source: Health News from Medical News Today)

Annual cost of defensive orthopaedic medicine estimated at $2 billion

EurekAlert! - Medicine and Health — Thu, 09 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) In a first-ever national survey of orthopaedic surgeons, 96 percent said they have practiced defensive medicine. (Source: EurekAlert! - Medicine and Health)

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AAN Press Release: Vote for Your Favorite Video! Public Voting Now Open for 2012 Neuro Film Festival

American Academy of Neurology — Thu, 09 Feb 2012 00:16:52 +0100

You can now begin voting for your favorite video entry to the 2012 Neuro Film Festival through March 8, 2012, at www.NeuroFilmFestival.com. (Source: American Academy of Neurology)

Spinning Sessions Trigger The Same Biochemical Indications As Heart Attacks

Health News from Medical News Today — Wed, 08 Feb 2012 09:00:00 +0100

A short spinning session can trigger the same biochemical indications as a heart attack - a reaction that is probably both natural and harmless, but should be borne in mind when people seek emergency treatment for chest pain, reveals a study from the Sahlgrenska Academy at the University of Gothenburg, Sweden. Heart attacks increase the secretion of enzymes known as cardiac biomarkers, which can be measured using a simple blood test. This is important for rapid diagnosis and initiation of treatment... (Source: Health News from Medical News Today)

Orthopaedic Experts Present Research, Clinical Advances At AAOS Meeting

Health News from Medical News Today — Wed, 08 Feb 2012 09:00:00 +0100

Experts from the Department of Orthopaedic Surgery at NYU Langone Medical Center are presenting their latest research and clinical findings on diseases of the muscle, tendon, bone and joint at the annual meeting of the American Academy of Orthopaedic Surgeons (AAOS), February 7-11 in San Francisco, California... (Source: Health News from Medical News Today)

Patient Sensitivity To Important Drug Target In Deadly Brain Cancer Predicted

Health News from Medical News Today — Wed, 08 Feb 2012 08:00:00 +0100

A recent discovery by Van Andel Research Institute (VARI) scientists enables the prediction of patient sensitivity to proposed drug therapies for glioblastoma - the most common and most aggressive malignant brain tumor in humans. The study, published in the Proceedings of the National Academy of Science, investigated glioblastoma models characterized by cell signaling activation and gene amplification for their susceptibility to inhibitors of both the human MET oncogene and the epidermal growth factor receptor (EFGR). An oncogene is a gene with the potential to cause cancer... (Source: Health News from Medical News Today)

Panic, Breathlessness And Unheard Pain: The Trauma Of Being On A Ventilator While Conscious

Health News from Medical News Today — Wed, 08 Feb 2012 08:00:00 +0100

More and more people being cared for on ventilators are conscious during the treatment, but what is it like to be fully conscious without being able to communicate with the world around you? A thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden, has lifted the lid on a world of panic, breathlessness and unheard pain. It has been far more common since the beginning of the 21st century for patients to be conscious during ventilator treatment... (Source: Health News from Medical News Today)

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Halting bone-building osteoporosis drug use cuts risk for additional atypical femur fracture in half

EurekAlert! - Medicine and Health — Wed, 08 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) There is growing evidence that supports an association between atypical fractures of the femur- a rare break of the thigh bone, typically without trauma - and the use of bisphosphonates, drugs proven to enhance bone density and reduce fracture incidence caused by osteoporosis. (Source: EurekAlert! - Medicine and Health)

Anxiety trait linked to postoperative pain in men following total knee replacement

EurekAlert! - Social and Behavioral Science — Wed, 08 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) In new research, men with anxiety traits were more likely to report post-operative pain ratings following total knee replacement (TKR) resulting in longer hospital stays, and women generally reported higher post-operative pain levels than men and were less satisfied with pain control. (Source: EurekAlert! - Social and Behavioral Science)

Video-based home exercise can minimize osteoarthritis pain, improve mobility

EurekAlert! - Social and Behavioral Science — Wed, 08 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Video-based home exercise programs can enhance adherence to a prescribed exercise program, reduce pain, improve physical function, and improve life quality in patients living with knee osteoarthritis. (Source: EurekAlert! - Social and Behavioral Science)

Antidepressant use linked with less patient satisfaction after hip replacement

EurekAlert! - Social and Behavioral Science — Wed, 08 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Patients taking antidepressants up to three years prior to undergoing a total hip replacement (THR) were more likely to report greater pain before and after surgery and less satisfaction with their procedure, according to new research presented today at the 2012 Annual Meeting of the American Academy of Orthopedic Surgeons (AAOS). (Source: EurekAlert! - Social and Behavioral Science)

Anxiety trait linked to post-operative pain in men following total knee replacement

EurekAlert! - Social and Behavioral Science — Wed, 08 Feb 2012 05:00:00 +0100

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Online support following joint replacement surgery is cost and time effective for patients

EurekAlert! - Medicine and Health — Wed, 08 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Web-based follow-up for total knee replacement (TKR) may provide significant time and cost savings to patients, according to new research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). (Source: EurekAlert! - Medicine and Health)

Obese children more likely to suffer growth plate fractures

EurekAlert! - Medicine and Health — Wed, 08 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Obese and overweight children are more likely to suffer growth plate fractures, and their injuries were more often from a "low-energy" impact, according to new research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons. (Source: EurekAlert! - Medicine and Health)

Excessive sporting activity may impair long-term success of hip resurfacing

EurekAlert! - Medicine and Health — Wed, 08 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) High impact sporting activities -- such as daily running or tennis -- can be detrimental to the long-term success of hip resurfacing arthroplasty, according to research presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS). (Source: EurekAlert! - Medicine and Health)

Dr. Ruth Williams becomes new AAO president

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Ruth D. Williams, MD, has begun her term as the 115th president of the American Academy of Ophthalmology. (Source: Modern Medicine)

AAO, ASCRS offer guidance on femtosecond billing

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

The American Academy of Ophthalmology and the American Society of Cataract and Refractive Surgery have issued guidelines to assist ophthalmologists in determining their ability to charge Medicare and/or its beneficiaries for use of a femtosecond laser during cataract surgery. (Source: Modern Medicine)

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Submit Course Proposals for the 2013 Annual Meeting

American Academy of Neurology — Tue, 07 Feb 2012 22:03:00 +0100

Proposals for the 2013 Annual Meeting are due May 11, 2012. (Source: American Academy of Neurology)

Peripheral Neuropathy Examined in Latest Continuum

American Academy of Neurology — Tue, 07 Feb 2012 17:03:00 +0100

The February issue of Continuum: Lifelong Learning in Neurology® focuses on peripheral neuropathy and offers the opportunity to earn up to 12 hours of AMA PRA Category 1 Credits™. (Source: American Academy of Neurology)

American Academy of Orthopaedic Surgeons (AAOS) 2012 Annual MeetingAmerican Academy of Orthopaedic Surgeons (AAOS) 2012 Annual Meeting

Medscape Today Headlines — Tue, 07 Feb 2012 16:13:10 +0100

Read clinically focused news coverage of key developments from the meeting. Medscape Ophthalmology (Source: Medscape Today Headlines)

New Prostate Cancer Drug Target Identified

Health News from Medical News Today — Tue, 07 Feb 2012 09:00:00 +0100

Research led by Wanguo Liu, PhD, Associate Professor of Genetics at LSU Health Sciences Center New Orleans, has identified a new protein critical to the development and growth of prostate cancer. The findings are published online in the Early Edition of Proceedings of the National Academy of Sciences, available the week of February 6, 2012. Dr. Liu and his team discovered a protein called ARD1 which is involved with the male hormone, androgen, and its receptor. Prostate cancer is a hormone-regulated disease and the main hormone is androgen... (Source: Health News from Medical News Today)

Taste Receptors Discovered In Pancreatic Beta Cells Can Sense Fructose And Stimulate Insulin Secretion

Health News from Medical News Today — Tue, 07 Feb 2012 09:00:00 +0100

Taste receptors on the tongue help us distinguish between safe food and food that's spoiled or toxic. But taste receptors are now being found in other organs, too. In a study published online the week of February 6 by the Proceedings of the National Academy of Sciences of the USA, researchers at Sanford-Burnham Medical Research Institute (Sanford-Burnham) discovered that beta cells in the pancreas use taste receptors to sense fructose, a type of sugar. According to the study, the beta cells respond to fructose by secreting insulin, a hormone that regulates the body's response to dietary sugar... (Source: Health News from Medical News Today)

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Knee replacement may lower a patient's risk for mortality and heart failure

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons highlights the benefits of total knee replacement. (Source: EurekAlert! - Medicine and Health)

Competitive soccer linked to increased injuries and menstrual dysfunction in girls

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) In the US, there are nearly three million youth soccer players, and half of them are female. New research presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons found that despite reporting appropriate body perception and attitudes toward eating, elite youth soccer athletes face an increased risk for delayed or irregular menstruation. (Source: EurekAlert! - Medicine and Health)

Vitamin D deficiency high among trauma patients

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) New research presented at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons found that 77 percent of trauma patients had deficient or insufficient levels of vitamin D. (Source: EurekAlert! - Medicine and Health)

Modern, low-energy ammunition can cause deep tissue damage

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Gunshot injuries are typically categorized as low- or high-energy based on the weapon's missile velocity and mass. (Source: EurekAlert! - Medicine and Health)

Economic factors impact orthopaedic trauma volume

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Economic trends impact orthopaedic trauma volume, according to new research presented today at the American Academy of Orthopaedic Surgeons 2012 Annual Meeting. (Source: EurekAlert! - Medicine and Health)

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Risk of pulmonary embolism greatest during first week following total joint replacement

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Anticoagulation treatment for more than seven days following total joint replacement may be unnecessary, according to new research presented today at the American Academy of Orthpaedic Surgeons 2012 Annual Meeting. (Source: EurekAlert! - Medicine and Health)

Aspirin may prevent DVT and PE in joint replacement patients

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Aspirin, along with the use of stockings and a foot pump, are safe and effective therapies in preventing deep vein thrombosis and pulmonary embolism in most joint replacement patients, according to research presented today at the American Academy of Orthopaedic Surgeons 2012 Annual Meeting. Patients at high risk for DVT made require the use of anticoagulation therapies. (Source: EurekAlert! - Medicine and Health)

44 percent of postmenopausal women with distal radius fracture have low levels of vitamin D

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Forty-four percent of postmenopausal women with a distal radius fracture have a low level of vitamin D, according to new research presented today at the 2012 Annual Meeting of the American Academy of Orthopaedic Surgeons. (Source: EurekAlert! - Medicine and Health)

Post surgical phone support improves outcome following knee replacement

EurekAlert! - Medicine and Health — Tue, 07 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Among high-risk Total Knee Replacement patients, those who received telephone support reported significantly higher post-surgical physical activity and function at six months. (Source: EurekAlert! - Medicine and Health)

Metabolic abnormalities associated with initiation of systemic treatment for psoriasis: evidence from the Italian Psocare Registry

Journal of the European Academy of Dermatology and Venereology — Tue, 07 Feb 2012 05:00:00 +0100

Conclusion Systemic treatments for psoriasis resulted in heterogeneous effects on the parameters analysed. (Source: Journal of the European Academy of Dermatology and Venereology)

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2012 Annual Meeting Evening Case Study Programs

American Academy of Neurology — Mon, 06 Feb 2012 21:54:00 +0100

All evening case study programs will be held on Thursday, April 26, 6:00 p..m.-9:00 p.m. (Source: American Academy of Neurology)

AAN Press Release: Who Will Benefit from Stroke Drug? New Score Can Help Decide

American Academy of Neurology — Mon, 06 Feb 2012 21:43:00 +0100

A new scoring method can help doctors quickly decide which stroke patients will respond well to the clot-busting drug alteplase. (Source: American Academy of Neurology)

Bad Immunity Genes - Why do They Survive?

Health News from Medical News Today — Mon, 06 Feb 2012 21:00:00 +0100

New evidence has been discovered by biologists at the University of Utah as to why people, mice and other vertebrate animals carry thousands of different genes to create major histocompatibility complex (MHCs) proteins, despite the fact that some of those genes make humans vulnerable to autoimmune diseases and infections. Findings from the study will be published online the week of February 6, 2012, in the journal Proceedings of the National Academy of Sciences. MHC proteins are found on the surface of most cells in vertebrates and define an individual's tissue type... (Source: Health News from Medical News Today)

Capitol Hill Report: It Just Keeps Getting More Expensive

American Academy of Neurology — Mon, 06 Feb 2012 15:41:00 +0100

Greetings again from Washington, where the cost of an SGR fix just keeps increasing. (Source: American Academy of Neurology)

Magic mushrooms, international law and the failed 'war on drugs'

Guardian Unlimited Science — Mon, 06 Feb 2012 12:36:26 +0100

Recent research suggesting potential therapeutic benefits of psilocybin focus attention on the need to reform drug lawsIt's been a busy fortnight. First the publication of two major peer-reviewed research papers about magic mushrooms that attracted worldwide publicity. Then off to Prague for an international drugs policy symposium. And just last week, news of a large grant for our next collaborative study with Imperial College. But I'm getting ahead of myself.I established the Beckley Foundation some 14 years ago as a think tank on drugs policy. It was apparent even then that the "war on drugs" had failed. A 1997 report by the United Nations Drugs Control Programme put the value of the global trade in illicit drugs at around $400bn. Recent UN figures show that global production of opium (u...

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The American Academy of Neurology position statement on abuse and violence. - Schulman EA, Hohler AD.

SafetyLit: All (Unduplicated) — Mon, 06 Feb 2012 11:54:53 +0100

Neurologists see patients with neurologic disabilities that render them susceptible to abuse or neglect. They also encounter patients with neurologic dysfunction that may be either directly or indirectly related to maltreatment. In 2008, the American Medic... (Source: SafetyLit: All (Unduplicated))

Gemba Academy Expands Global Server Network Delivering Online Lean...

PRWeb: Medical Pharmaceuticals — Mon, 06 Feb 2012 06:00:14 +0100

Gemba Academy has expanded its server network to twenty-four locations around the globe. This allows for the efficient delivery of high definition on-demand lean enterprise and lean manufacturing...(PRWeb February 05, 2012)Read the full story at http://www.prweb.com/releases/2012/2/prweb9168250.htm (Source: PRWeb: Medical Pharmaceuticals)

It's not solitaire: Brain activity differs when one plays against others

EurekAlert! - Social and Behavioral Science — Mon, 06 Feb 2012 05:00:00 +0100

(University of Illinois at Urbana-Champaign) Researchers have found a way to study how our brains assess the behavior -- and likely future actions -- of others during competitive social interactions. Their study, described in a paper in the Proceedings of the National Academy of Sciences, is the first to use a computational approach to tease out differing patterns of brain activity during these interactions, the researchers report. (Source: EurekAlert! - Social and Behavioral Science)

Geometry, not gender

EurekAlert! - Medicine and Health — Mon, 06 Feb 2012 05:00:00 +0100

(American Academy of Orthopaedic Surgeons) Much orthopaedic research has been devoted to determining why women are far more susceptible to knee ligament injuries than men. According to a new study, the answer may lie in geometry -- the length and shape of a patient's knee bone -- more than gender. (Source: EurekAlert! - Medicine and Health)

Optimism and humour can help to combat dental fear

EurekAlert! - Social and Behavioral Science — Mon, 06 Feb 2012 05:00:00 +0100

(University of Gothenburg) Scientists at the Sahlgrenska Academy, University of Gothenburg, Sweden, have investigated the strategies used by people who suffer from dental fear to cope with dental treatment. Some of the most important factors in managing stress during a visit to the dentist include optimism on the part of the patient and an atmosphere of humor in the interaction with the dental staff. (Source: EurekAlert! - Social and Behavioral Science)

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Injectable progesterone contraceptives may be associated with poor periodontal health

EurekAlert! - Medicine and Health — Mon, 06 Feb 2012 05:00:00 +0100

(American Academy of Periodontology) Injectable progesterone contraceptives may be associated with poor periodontal health, according to research in the Journal of Periodontology. The study found that women who are currently taking depotmedroxyprogesterone acetate injectable contraceptive, or have taken DMPA in the past, are more likely to have indicators of poor periodontal health, including gingivitis and periodontitis, than women who have never taken the injectable contraceptive. (Source: EurekAlert! - Medicine and Health)

Traumatic to be on a ventilator treatment while conscious

EurekAlert! - Medicine and Health — Mon, 06 Feb 2012 05:00:00 +0100

(University of Gothenburg) More and more people being cared for on ventilators are conscious during the treatment, but what is it like to be fully conscious without being able to communicate with the world around you? A thesis from the Sahlgrenska Academy at the University of Gothenburg, Sweden, has lifted the lid on a world of panic, breathlessness and unheard pain. (Source: EurekAlert! - Medicine and Health)

Spinning sessions trigger the same biochemical indications as heart attacks

EurekAlert! - Medicine and Health — Mon, 06 Feb 2012 05:00:00 +0100

(University of Gothenburg) A short spinning session can trigger the same biochemical indications as a heart attack -- a reaction that is probably both natural and harmless, but should be borne in mind when people seek emergency treatment for chest pain, reveals a study from the Sahlgrenska Academy at the University of Gothenburg, Sweden. (Source: EurekAlert! - Medicine and Health)

NYU Langone orthopaedic experts present research, clinical advances at AAOS meeting

EurekAlert! - Social and Behavioral Science — Mon, 06 Feb 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Experts from the Department of Orthopaedic Surgery at NYU Langone Medical Center will present their latest research and clinical findings on diseases of the muscle, tendon, bone and joint at the annual meeting of the American Academy of Orthopaedic Surgeons, Feb. 7-11 in San Francisco, California. (Source: EurekAlert! - Social and Behavioral Science)

A team of CRCHUM researchers paves the way for improving treatment for Type 2 diabetes

EurekAlert! - Medicine and Health — Mon, 06 Feb 2012 05:00:00 +0100

(Centre hospitalier de l'Université de Montréal) In a study published last week in Proceedings of the National Academy of Sciences, a team led by Dr. Vincent Poitout of the University of Montreal Hospital Research Centre has made an important step forward in understanding how insulin secretion is regulated in the body. This discovery has important implications for drugs currently in development to treat Type 2 diabetes, a disease which is diagnosed every 10 seconds somewhere throughout the world. (Source: EurekAlert! - Medicine and Health)

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One hundred years of allergen immunotherapy European Academy of Allergy and Clinical Immunology celebration: review of unanswered questions

Allergy — Mon, 06 Feb 2012 05:00:00 +0100

This study presents outcomes and conclusions from these discussions. (Source: Allergy)

Media Alert: Injectable Progesterone Contraceptives May Be Associated with Poor Periodontal Health

American Academy of Periodontology News Releases — Mon, 06 Feb 2012 05:00:00 +0100

A study published in the Journal of Periodontology found that current and past users of the contraceptive depot medroxyprogesterone acetate (DMPA) had increased markers of poor periodontal health compared to women who have never used it. (American Academy of Periodontology press release) (Source: American Academy of Periodontology News Releases)

Optimizing curettage with a ‘backhand’

Journal of the European Academy of Dermatology and Venereology — Mon, 06 Feb 2012 05:00:00 +0100

(Source: Journal of the European Academy of Dermatology and Venereology)

The American Academy of Neurology position statement on abuse and violence

Neurology — Mon, 06 Feb 2012 05:00:00 +0100

(Source: Neurology)

Comparison of Systematic Developmental Surveillance With Standardized Developmental Screening in Primary Care

Clinical Pediatrics — Mon, 06 Feb 2012 05:00:00 +0100

Many physicians use surveillance questions to assess development; the American Academy of Pediatrics recommends screening at 9-, 18-, and 24-month health supervision visits (HSVs). There are no studies directly comparing surveillance with screening. The authors directly compared systematic surveillance with standardized screening using a cross-sectional observational study of children with no known delays. Surveillance questions were completed at each HSV. The Ages and Stages Questionnaire (ASQ) was administered following the 9-, 18-, or 24-month HSV. The authors compared detection of delays by surveillance with ASQ screening. Using surveillance, 11/95 subjects were identified as delayed. Using the ASQ, 15/95 subjects scored fail; 28/95 scored monitor. Among the 11 delayed surveillance sub...

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The skin‐blanching assay

Journal of the European Academy of Dermatology and Venereology — Sat, 04 Feb 2012 05:00:00 +0100

AbstractThe skin‐blanching assay is used for the determination and bioequivalence of dermatologic glucocorticoids (GCs). The exact mechanism of the production of blanching is not fully understood, but it is considered that local vasoconstriction of the skin microvasculature and the consequent blood‐flow reduction cause this phenomenon. Several factors influence skin blanching, including drug concentration, duration of application, nature of vehicle, occlusion, posture and location. The intensity of vasoconstriction can be measured in several ways: visual or quantitative methods, such as reflectance spectroscopy, thermography, laser Doppler velocimetry and chromametry. In literature, contradicting results in the correlation of the skin‐blanching assay with different tests to determine...

The Power of Film as Storyteller: Oscar Nominee “The Help”

Psychology Today Relationships Center — Fri, 03 Feb 2012 23:34:12 +0100

Oscar nominee The Help tackles racism and sexism and views motherhood, daughterhood and friendship along the lines of authenticity.read more (Source: Psychology Today Relationships Center)

Schism over H5N1 Avian Flu Research Leaks Out

Scientific American - Official RSS Feed — Fri, 03 Feb 2012 21:44:00 +0100

Caption: Electron micrograph of H5N1 virus (gold) Image: CDC/Courtesy of Cynthia Goldsmith; Jacqueline Katz; Sherif R. Zaki NEW YORK Sparks flew Thursday night at a New York Academy of Sciences panel discussion about whether or not certain recent research into the H5N1 avian flu virus has created a major biosecurity threat and what, if anything, to do about it. [More] (Source: Scientific American - Official RSS Feed)

US Pediatricians Recommend Routine HPV Vaccination For Boys

Health News from Medical News Today — Fri, 03 Feb 2012 20:00:00 +0100

As part of a revised standard published this week, the American Academy of Pediatrics says boys should be routinely vaccinated against the human papillomavirus (HPV), a common virus that is spread through sexual contact. Although there are dozens of types of HPV, vaccines can protect both male and females against some of the more common types that can lead to disease and cancer... (Source: Health News from Medical News Today)

Gemcitabine in combination with vinorelbine in elderly patients with anthracycline- and taxane-pretreated metastatic breast cancer

Cancer Chemotherapy and Pharmacology — Fri, 03 Feb 2012 17:12:25 +0100

Conclusion Gemcitabine in combination with vinorelbine is active and safe in elderly patients with anthracycline- and taxane-pretreated metastatic breast cancer. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00280-012-1830-1Authors Ningning Dong, Key laboratory of Carcinogenesis and Translational Research (Ministry of Education), Medical Oncology Department, Peking University School of Oncology, Beijing Cancer Hospital & Institute, 52 Fucheng Rd, Beijing, 100142 ChinaMingyu Wang, Chemotherapy Department, Shandong Tumor Hospital and Institute, 440 Jiyan Rd, Jinan, 250117 ChinaHuiqing Li, Epidemiology Department, Institute of Basic Medicine, Shandong Academy of Medical Sciences, 18877 Jingshi Rd, Jinan, 250062 ChinaYongchun Cui, Clinical Tr...

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Are intravenous injections of contrast media really less nephrotoxic than intra-arterial injections?

European Radiology — Fri, 03 Feb 2012 17:11:57 +0100

Abstract We oppose the opinion that the intra-arterial administration of iodine-based contrast media (CM) appears to pose a greater risk of contrast medium-induced nephropathy (CIN) than intravenous administration since 1) in intra-arterial coronary procedures and most other intra-arterial angiographic examinations, CM injections are also intravenous relative to the kidneys, 2) there is a lack of comparative trials studying the risk of CIN between intra-arterial and intravenous procedures with matched risk factors and CM doses, 3) a bias selection of patients with fewer risk factors may explain the seemingly lower rate of CIN after CT in comparison with coronary interventions, 4) the rate of CIN following intra-arterial coronary procedures may also be exaggerated owing to ...

Penn State defies Facebook campaign calling for it to drop climate lecture | Leo Hickman

Guardian Unlimited Science — Fri, 03 Feb 2012 16:13:14 +0100

University cites its First Amendment commitment in supporting its climate scientist Michael Mann's right to give lectureIn an uncharacteristically angry post at the New York Times's Dot Earth blog, Andy Revkin has hit out at a "shameful attack on free speech". It relates to a Facebook campaign which is calling on Pennsylvania State University to "disinvite" Professor Michael E. Mann, the director of its Earth System Science Center, from giving a lecture next week entitled: "Confronting the Climate Change Challenge."The Facebook campaign has been initiated by a seemingly conjoined group called the Common Sense Movement/Secure Energy for America Political Action Committee. Brad Johnson at ThinkProgress has investigated the people behind it and describes it as a "coal-industry astroturf group...

Alzheimer's-Related Protein In Brains Of Healthy Adults May Shed Light On Earliest Signs Of Disease

Health News from Medical News Today — Fri, 03 Feb 2012 08:00:00 +0100

Researchers from the Center for Vital Longevity at the University of Texas at Dallas and UT Southwestern Medical Center have completed a large-scale neuroimaging study of healthy adults from age 30 to 90 that measured beta-amyloid protein - a substance whose toxic buildup in the brain is a diagnostic marker for Alzheimer's disease. The findings, published in the online issue of Neurology, the medical journal of the American Academy of Neurology, mark a crucial step toward being able to predict who may be at risk for developing Alzheimer's disease long before symptoms appear... (Source: Health News from Medical News Today)

AAN Press Release: Marker for Alzheimer's Disease May Affect Mental Function Even in Healthy Adults

American Academy of Neurology — Fri, 03 Feb 2012 00:16:34 +0100

High levels of the protein beta-amyloid in the brain that is associated with Alzheimer's disease may affect brain performance even in healthy adults, according to a study published in the February 1, 2012, online issue of Neurology®. (Source: American Academy of Neurology)

Regulation of Complement Factor H (CFH) by Multiple miRNAs in Alzheimer’s Disease (AD) Brain

Molecular Neurobiology — Thu, 02 Feb 2012 18:16:22 +0100

Abstract Human brain cells rely on a specific subset of microRNAs (miRNAs or miRs) to shape their gene expression patterns, and this is mediated through microRNA effects on messenger RNA (mRNA) speciation and complexity. In recent studies (a) in short post-mortem interval Alzheimer’ disease (AD) brain tissues versus age-matched controls, and (b) in pro-inflammatory cytokine- and Aβ42 peptide-stressed human neuronal-glial (HNG) cells in primary culture, we have identified several brain-abundant miRNA species found to be significantly up-regulated, including miR-125b and miR-146a. Both of these nuclear factor kappa B (NF-κB)-activated, 22 nucleotide small non-coding RNAs (sncRNAs) target the mRNA of the key, innate-immune- and inflammation-related regulatory protein, com...

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Adjuvant vaccination with melanoma antigen-pulsed dendritic cells in stage III melanoma patients

Medical Oncology — Thu, 02 Feb 2012 18:16:09 +0100

Abstract Dendritic cells may be successfully used to induce in vivo-specific anti-tumor responses when combined with the appropriate antigen in the appropriate context. The purpose of this study was to evaluate efficacy of peptide-loaded DC vaccine in high-risk stage III melanoma patients after lymph node dissection (LND). HLA-A2+, -A1+, or -A3+ melanoma patients (N = 22), stage III, N1b-N3, received 5–16 (median: 11) DC vaccines loaded with MHC class-I-restricted melanoma peptides respective to the patient’s haplotype, and with autologous tumor lysate, if available. Vaccinated patients were matched to unvaccinated stage III controls (22 of 869) by sex, number of metastatic lymph nodes, extracapsular involvement, LND type, Breslow stage, and ulceration. Vaccin...

HEA Health Sciences Conference 2012

MEDEV News — Thu, 02 Feb 2012 15:21:55 +0100

The Health Sciences discipline cluster is based at the Higher Education Academy in York and consists of a core of 11 team members who are spread across the UK. The cluster primarily represents the disciplines of Nursing, Medicine Dentistry and Veterinary science and all subjects related to health. The first annual conference for the Health Sciences disciplines is to be held at the East Midlands Conference Centre on Thursday 31st May 2012. The focus of the conference will be: nnovative practice in Healthcare learning and teaching Simulation in Healthcare education Evolution of Technology enhanced learning in Healthcare education The delegate rate for conference attendance is £50 per attendee (not including any accommodation required) Attendees requiring financial assistance with tra...

Effects of Radiation Exposure From Cardiac Imaging: How Good Are the Data?

Journal of the American College of Cardiology — Thu, 02 Feb 2012 13:55:34 +0100

Concerns about medical exposure to ionizing radiation have become heightened in recent years as a result of rapid growth in procedure volumes and the high radiation doses incurred from some procedures. This paper summarizes the evidence base undergirding concerns about radiation exposure in cardiac imaging. After classifying radiation effects, explaining terminology used to quantify the radiation received by patients, and describing typical doses from cardiac imaging procedures, this paper will address the major epidemiological studies having bearing on radiation effects at doses comparable to those received by patients undergoing cardiac imaging. These include studies of atomic bomb survivors, nuclear industry workers, and children exposed in utero to x-rays, all of which have evidenced i...

Pneumonia Survival May Improve With Stimulation Of Brain Hormone Action

Health News from Medical News Today — Thu, 02 Feb 2012 08:00:00 +0100

An international research team may have found a way to block a second wave of death that can result from pneumonia treatment. Antibiotics are effective at killing pneumococcus - the cause of about 50 percent of pneumonias - but as it dies the bacterium releases potentially lethal toxins. Adding an agonist that mimics the action of growth hormone-releasing hormone - which ultimately enables growth - may stop that second wave, according to research published in the Proceedings of the National Academy of Sciences... (Source: Health News from Medical News Today)

AMCP objects to proposed reporting requirements for Part D

Drug Topics - Top News — Thu, 02 Feb 2012 05:00:00 +0100

The Academy of Managed Care Pharmacy is not pleased with changes to the Medicare Part D reporting requirements proposed by the Centers for Medicare and Medicaid Services. (Source: Drug Topics - Top News)

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Dr. Edds named AACS president

Modern Medicine — Thu, 02 Feb 2012 05:00:00 +0100

Gerald Edds, M.D., is the new president of the American Academy of Cosmetic Surgery. Dr. Edds was officially inducted at the Chicago-based academy’s 28th Annual Scientific Meeting, held recently in Las Vegas. (Source: Modern Medicine)

AMCP objects to proposed reporting requirements for Part D

Drug Topics - Pharmacy News — Thu, 02 Feb 2012 05:00:00 +0100

Primary immunodeficiency diseases in the Middle East

Annals of the New York Academy of Sciences — Thu, 02 Feb 2012 05:00:00 +0100

Reports on primary immunodeficiency diseases (PIDs) have clearly shown wide geographic and ethnic variations. Understanding these variations is expected to play a major role in improving the diagnosis and management of such diseases, and will also affect research on PIDs. In this short review, we explore the unique aspects of primary immunodeficiencies in the Middle East. (Source: Annals of the New York Academy of Sciences)

Thigh Muscle Injuries in Youth Soccer: Predictors of Recovery

The American Journal of Sports Medicine — Thu, 02 Feb 2012 05:00:00 +0100

Conclusion: The risk for prolonged recovery from thigh muscle injury was found to increase with age of the player and contact mechanism. The risk of injury increased toward the end of the first half, and this risk persisted throughout the second half. Delayed recovery was significantly associated with a hamstring muscle injury, first injury, and contact mechanism. This study, for the first time, allows identification of youth male soccer players at high-risk for prolonged symptoms after thigh muscle injury. (Source: The American Journal of Sports Medicine)

HPV vaccine recommended for boys

Health Facts and Fears — Thu, 02 Feb 2012 05:00:00 +0100

Both the Centers for Disease Control and Prevention and the American Academy of Pediatrics are now advising parents to vaccinate their boys against the human papillomavirus (HPV), especially before they become sexually active. (Source: Health Facts and Fears)

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AAN Leaders Meet with Head of Innovation Center on Stroke, Alzheimer's Care

American Academy of Neurology — Wed, 01 Feb 2012 22:39:00 +0100

The group stressed that neurologists should be involved in testing new care and payment models. (Source: American Academy of Neurology)

Wall Street Journal rapped over climate change stance

Guardian Unlimited Science — Wed, 01 Feb 2012 19:12:08 +0100

Leading scientists, including climate change experts, complain about opinion piece akin to 'dentists practising cardiology'The Wall Street Journal has received a dressing down from a large group of leading scientists for promoting retrograde and out-of-date views on climate change.In an opinion piece run by the Journal on Wednesday, nearly 40 scientists, including acknowledged climate change experts, took on the paper for publishing an article disputing the evidence on global warming.The offending article, No Need to Panic About Global Warming, which appeared last week, argued that climate change was a cunning ploy deployed by governments to raise taxes and by non-profit organisations to solicit donations to save the planet.It was signed by 16 scientists who don't subscribe to the conventi...

Plasma Ghrelin Levels in Patients with Familial Mediterranean Fever

Digestive Diseases and Sciences — Wed, 01 Feb 2012 17:12:06 +0100

Conclusions In this study, high ghrelin levels were measured during attacks in FMF patients. This finding is in line with previous results regarding the fact that inflammatory response arising during an FMF attack is an acute inflammatory event. Our findings suggest that ghrelin levels measured during FMF attacks could be used as a biochemical indicator for the FMF attack in FMF patients and that it could be used for support of the diagnosis of the disease. Content Type Journal ArticleCategory Original ArticlePages 1-4DOI 10.1007/s10620-012-2049-zAuthors Zulfikar Polat, Department of Gastroenterology, Gulhane Military Medical Academy, School of Medicine, Etlik, Ankara, TurkeyGuldem Kilciler, Department of Gastroenterology, Gulhane Military Medical Academy, School o...

AAN-Joint Commission Speak Up Campaign Provides Advice on Early Signs and Risks of Stroke

American Academy of Neurology — Wed, 01 Feb 2012 16:33:00 +0100

The Joint Commission is launching this campaign, which coincides with the February 1-3 International Stroke Conference 2012, to help Americans understand the importance of preventing strokes and seeking immediate treatment when they occur. (Source: American Academy of Neurology)

Report Selects 16 Highest Priorities to Guide NASA's Technology Development Efforts

News from the National Academies — Wed, 01 Feb 2012 15:57:49 +0100

During the next five years, NASA technology development efforts should focus on 16 high-priority technologies and their associated top technical challenges, says a new report from the National Research Council. The technologies were selected with input from the external technical community as part of NASA’s draft technology roadmaps and include items such as radiation mitigation; guidance, navigation, and control; nuclear systems for both power generation and transportation; and solar power generation (see news release for full table). These priorities were chosen to align with three main facets of NASA's overall mission: extending and sustaining human activities beyond low Earth orbit; exploring the evolution of the solar system and the potential for life elsewhere; and expanding our un...

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Last Chance to Register for February 7 EHR Implementation Webinar: What You Need to Know from A-Z

American Academy of Neurology — Wed, 01 Feb 2012 14:49:00 +0100

Take advantage of reduced rates and register by February 3. (Source: American Academy of Neurology)

AAP Updates Childhood and Adolescent Immunization SchedulesAAP Updates Childhood and Adolescent Immunization Schedules

Medscape Today Headlines — Wed, 01 Feb 2012 11:19:32 +0100

The American Academy of Pediatrics has issued the 2012 immunization schedules for children and adolescents and advises clinicians to use all 3 schedules together, not as stand-alone schedules. Medscape Medical News (Source: Medscape Today Headlines)

HPV Vaccine for Boys added to new Immunization Schedule

About.com Pediatrics — Wed, 01 Feb 2012 11:03:59 +0100

The new immunization schedule from the American Academy of Pediatrics is out today, and as expected, there weren't any surprises. The one big change is that there is a new recommendation that all boys, just like girls, should now routinely get three doses of the HPV vaccines when they are 11 or 12 years old. That shouldn't be a surprise though, as giving the HPV vaccine to boys is something that has been discussed since last year....Read Full Post (Source: About.com Pediatrics)

Higher Education Academy health sciences newsletter

MEDEV News — Wed, 01 Feb 2012 09:43:49 +0100

The new Health Sciences team at the Higher Education Academy have just issued their first newsletter containing details of apointments, news, events and funding opportunities. It can be viewed here - HealthScinewsletter1 (Source: MEDEV News)

National Study Shows Majority Of Self-Harming Adolescents Don't Receive A Mental Health Assessment During Emergency Room Visit

Health News from Medical News Today — Wed, 01 Feb 2012 09:00:00 +0100

A national study of Medicaid data shows most young people who present to emergency departments with deliberate self-harm are discharged to the community, without receiving an emergency mental health assessment. Even more, a roughly comparable proportion of these patients receive no outpatient mental health care in the following month. These are the findings from a study conducted by researchers at Nationwide Children's Hospital that appears in the Journal of the American Academy of Child & Adolescent Psychiatry... (Source: Health News from Medical News Today)

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Mom's Love Good For Child's Brain

Health News from Medical News Today — Wed, 01 Feb 2012 08:00:00 +0100

School-age children whose mothers nurtured them early in life have brains with a larger hippocampus, a key structure important to learning, memory and response to stress. The new research, by child psychiatrists and neuroscientists at Washington University School of Medicine in St. Louis, is the first to show that changes in this critical region of children's brain anatomy are linked to a mother's nurturing. Their research is published online in the Proceedings of the National Academy of Sciences Early Edition... (Source: Health News from Medical News Today)

Asia-Pacific Journal of Ophthalmology launches

Modern Medicine — Wed, 01 Feb 2012 05:00:00 +0100

The first issue of the Asia-Pacific Journal of Ophthalmology (APJO), the official publication of the Asia-Pacific Academy of Ophthalmology, was formally released online Jan. 23, a date coinciding with the Chinese New Year. (Source: Modern Medicine)

This Month in the Journal of the Academy of Nutrition and Dietetics

Journal of the American Dietetic Association — Wed, 01 Feb 2012 05:00:00 +0100

(Source: Journal of the American Dietetic Association)

Competency Is More than a Credential

Journal of the American Dietetic Association — Wed, 01 Feb 2012 05:00:00 +0100

We have begun our second month as the Academy of Nutrition and Dietetics. One of the many reasons for adopting this name is to signify that we—individually and collectively, as an organization and a profession—stand at the forefront of the global profession of dietetics. Our name signals the ever-increasing impact we will—and must—make on the nutritional health of people throughout the world in the coming years and decades. (Source: Journal of the American Dietetic Association)

Communication and Education for Families Dealing with End-of-Life Decisions

Journal of the American Dietetic Association — Wed, 01 Feb 2012 05:00:00 +0100

This article demonstrates how several ethical principles in the Code address the values and obligations of the dietetics practitioner when communicating with and educating families as they deal with end-of-life decisions. (Source: Journal of the American Dietetic Association)

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2011 Lenna Frances Cooper Memorial Lecture: The Road to HEaLth Is Paved with Good InVentions: Of Science, Sense, and Elephense

Journal of the American Dietetic Association — Wed, 01 Feb 2012 05:00:00 +0100

We claim as a matter of routine that “knowledge is power.” But we have known for decades—indeed, centuries—that diet is a cornerstone of health, yet we have failed to achieve optimal dietary patterns for all. We have known the leading causes of premature death and chronic disease in the United States for 2 decades or more, and have done relatively little with the information. Knowledge may be necessary for power, but it is clearly not sufficient. Knowledge may be prerequisite to power, but is clearly not commensurate with it. The gap between what we know and what we do in disease prevention and health promotion, and specifically in the application of nutrition to these goals, belies the wishful thinking that just knowing is enough. What is required to bridge this gap? What operatio...

Position Paper Update for 2012

Journal of the American Dietetic Association — Wed, 01 Feb 2012 05:00:00 +0100

The House of Delegates (HOD) approved the proposed position paper concept “The Role of Nutrition Genomics in Dietetics” in January 2011. The position paper is under development. Publication is planned for early 2013. The following is a list of all current positions of the Academy of Nutrition and Dietetics. (Source: Journal of the American Dietetic Association)

February 2012 People & Events

Journal of the American Dietetic Association — Wed, 01 Feb 2012 05:00:00 +0100

2012 Academy Food & Nutrition Conference & Expo October 6-9, 2012 Philadelphia, PA (Source: Journal of the American Dietetic Association)

The Huddleson Award 2011: Recognize research excellence—Nominate an article published in the 2011 Journal for the Huddleson

Journal of the American Dietetic Association — Wed, 01 Feb 2012 05:00:00 +0100

Every year the Journal of the Academy of Nutrition and Dietetics is proud to present its readers with a variety of revealing and insightful articles that expand the perimeters of nutrition science. While every article featured in this publication reflects a worthy contribution to the dietetics profession, each year there are a select number of articles whose research and content are so exceptional that they deserve to be recognized by the Academy. (Source: Journal of the American Dietetic Association)

Drinking Frequency as a Brief Screen for Adolescent Alcohol Problems

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

The American Academy of Pediatrics recommends routine alcohol screening for all adolescents. Problem-based substance use screens for adolescents exist, but have limitations. A consumption-based alcohol screen could provide an empirically validated, very brief method to screen youth for alcohol-related problems. National sample data indicate that frequency of alcohol use has high sensitivity and specificity in identifying youth with alcohol-related problems. A range of age-specific frequency cut scores perform well; specific cut points can be selected based on the screening context. (Read the full article) (Source: PEDIATRICS)

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Cardiac Screening Prior to Stimulant Treatment of ADHD: A Survey of US-Based Pediatricians

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: Variable pediatrician attitudes and cardiac screening practices reflect the limited evidence base and conflicting guidelines regarding cardiac screening. Barriers to identifying cardiac disorders influence practice. (Source: PEDIATRICS)

Recommended Childhood and Adolescent Immunization Schedules--United States, 2012

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

(Source: PEDIATRICS)

School-Based Health Centers and Pediatric Practice

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

School-based health centers (SBHCs) have become an important method of health care delivery for the youth of our nation. Although they only represent 1 aspect of a coordinated school health program approach, SBHCs have provided access to health care services for youth confronted with age, financial, cultural, and geographic barriers. A fundamental principle of SBHCs is to create an environment of service coordination and collaboration that addresses the health needs and well-being of youth with health disparities or poor access to health care services. Some pediatricians have concerns that these centers are in conflict with the primary care provider’s medical home. This policy provides an overview of SBHCs and some of their documented benefits, addresses the issue of potential confli...

Patient- and Family-Centered Care and the Pediatrician's Role

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

Drawing on several decades of work with families, pediatricians, other health care professionals, and policy makers, the American Academy of Pediatrics provides a definition of patient- and family-centered care. In pediatrics, patient- and family-centered care is based on the understanding that the family is the child’s primary source of strength and support. Further, this approach to care recognizes that the perspectives and information provided by families, children, and young adults are essential components of high-quality clinical decision-making, and that patients and family are integral partners with the health care team. This policy statement outlines the core principles of patient- and family-centered care, summarizes some of the recent literature linking patient- and family-...

Neonatal Drug Withdrawal

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

Maternal use of certain drugs during pregnancy can result in transient neonatal signs consistent with withdrawal or acute toxicity or cause sustained signs consistent with a lasting drug effect. In addition, hospitalized infants who are treated with opioids or benzodiazepines to provide analgesia or sedation may be at risk for manifesting signs of withdrawal. This statement updates information about the clinical presentation of infants exposed to intrauterine drugs and the therapeutic options for treatment of withdrawal and is expanded to include evidence-based approaches to the management of the hospitalized infant who requires weaning from analgesics or sedatives. (Source: PEDIATRICS)

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AAP Publications Reaffirmed

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

(Source: PEDIATRICS)

Dispensing Medications at the Hospital Upon Discharge From an Emergency Department

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

Although most health care services can and should be provided by their medical home, children will be referred or require visits to the emergency department (ED) for emergent clinical conditions or injuries. Continuation of medical care after discharge from an ED is dependent on parents or caregivers’ understanding of and compliance with follow-up instructions and on adherence to medication recommendations. ED visits often occur at times when the majority of pharmacies are not open and caregivers are concerned with getting their ill or injured child directly home. Approximately one-third of patients fail to obtain priority medications from a pharmacy after discharge from an ED. The option of judiciously dispensing ED discharge medications from the ED’s outpatient pharmacy withi...

Statement of Endorsement--Diabetes Care for Emerging Adults

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

(Source: PEDIATRICS)

Interview with Dr. Klaus Minde, MD: (interviewed by Normand Carrey MD).

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

Authors: PMID: 22299018 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Commentary: De Novo Self-Mutilation and Depressive Symptoms in a 17-year-old Adolescent Girl Receiving Depot-Medroxyprogesterone Acetate.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Toffol E, Heikinheimo O, Partonen T PMID: 22299017 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

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Clinical Case Rounds in Child and Adolescent Psychiatry: De Novo Self-Mutilation and Depressive Symptoms in a 17-year-old Adolescent Girl Receiving Depot-Medroxyprogesterone Acetate.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

We report the case of a 17-year-old adolescent girl who presented with de novo self-mutilation and depressive symptoms three and a half weeks after the administration of 150 mg of Depot-Medroxyprogesterone Acetate (DMPA). METHOD: Clinical case report and literature review. Possible confounding factors are reviewed. RESULTS: The patient had no personal psychiatric history and no significant family psychiatric history. A DSM-IV diagnosis of "mood disorder due to DMPA with depressive features" was formulated. There was no evidence of abnormal personality functioning. The mental status exam and collateral information validated the severity of her condition. DISCUSSION: DMPA is a birth control method especially useful for adolescent girls and possible secondary mood symptoms should ...

Attention deficit hyperactivity disorder (ADHD) in children, seasonal photoperiods, nocturnal movements and diurnal agitation.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: According to these results, this type of research should be reproduced in other Nordic countries and should include a larger sample group of children diagnosed with ADHD. PMID: 22299015 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Assessment and treatment of pediatric eating disorders: a survey of physicians and psychologists.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSION: In Ontario, primary care clinicians may benefit from more training and support to better identify and treat children and adolescents with eating disorders. In particular, clinicians may require additional training around screening, multi-informant assessment methods, as well as appropriate therapy techniques. PMID: 22299014 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Government Monitoring of the Mental Health of Children in Canada: Five Surveys (Part II).

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: Governments wanted a national strategy, national framework and agreement on a measuring agency. Good general agreement existed about reporting criteria. A partnership model may lead to quicker results given the difficulties within governments. NGOs and others need to continue collaborative advocacy. Monitoring is one of two steps that could help turn collections of services into self-regulating systems. PMID: 22299013 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Government monitoring of the mental health of children in Canada: five surveys (part I).

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: It was reassuring that governments supported monitoring and were producing reports. The Partnership Model may offer a suitable alternative for governments. Results of 2006 and 2008, discussion, conclusions and references are in Part II. PMID: 22299012 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

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Clinical characteristics of depressed youths in child psychiatry.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSION: : It is as important to assess depressive symptoms and suicidal ideation among young boys with behavioral difficulties as in adolescent boys and girls. Family functioning is important to consider in evaluating and treating youth. PMID: 22299011 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Maternal Stress during Pregnancy, ADHD Symptomatology in Children and Genotype: Gene-Environment Interaction.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: Maternal stress during pregnancy was associated with the development of ADHD symptomatology after controlling for family history of ADHD and other environmental factors. This association could partly be mediated through the DRD4 genotype. PMID: 22299010 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Childhood depression revisited: indicators, normative tests, and clinical course.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Thompson AH PMID: 22299009 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Occupy this and a sense of what is important.

Journal of the Canadian Academy of Child and Adolescent Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Carrey N PMID: 22299008 [PubMed - in process] (Source: Journal of the Canadian Academy of Child and Adolescent Psychiatry)

Mitotic rate and subcutaneous involvement are prognostic factors for survival after recurrence in patients with only locoregional skin metastasis as the first site of recurrence from cutaneous melanoma

Journal of the European Academy of Dermatology and Venereology — Wed, 01 Feb 2012 05:00:00 +0100

Conclusion The survival after recurrence of melanoma patients that has relapsed with only locoregional cutaneous metastasis depends on the mitotic rate of the primary tumor and the subcutaneous involvement of the metastasis. (Source: Journal of the European Academy of Dermatology and Venereology)

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Unique features of PTCH1 mutation spectrum in Chinese sporadic basal cell carcinoma

Journal of the European Academy of Dermatology and Venereology — Wed, 01 Feb 2012 05:00:00 +0100

Conclusion Mutations and LOH in PTCH1 were also highly prevalent in Chinese sporadic BCCs. However, UV light plays a less role in causing these mutations, suggesting other potential mechanisms in the development of sporadic BCC in Chinese patients. (Source: Journal of the European Academy of Dermatology and Venereology)

A Parent's Nurturing Results In Larger Hippocampus In Children

Health News from Medical News Today — Tue, 31 Jan 2012 23:00:00 +0100

A recent study by child psychiatrists and neuroscientists at Washington University School of Medicine in St Louis, published online in the Proceedings of the National Academy of Sciences Early Edition, states that children whose mothers showed them love and affection from the very beginning have brains with a larger hippocampus, which is a key part of the brain involved with memory, stress response, and learning. The hippocampus is a very important element of the brain... (Source: Health News from Medical News Today)

AAN Press Release: Press Room Registration Now Open for American Academy of Neurology Annual Meeting

American Academy of Neurology — Tue, 31 Jan 2012 22:05:00 +0100

The AAN Annual Meeting is the world's largest gathering of neurologists who come together to share the latest advances in neurologic research. (Source: American Academy of Neurology)

Corboy to Receive President's Award

American Academy of Neurology — Tue, 31 Jan 2012 17:17:00 +0100

John R. Corboy, MD, FAAN, will be presented with the President's Award preceding the Presidential Plenary Session on Tuesday, April 24. (Source: American Academy of Neurology)

Transient Aplastic Crisis in Hereditary Elliptocytosis

Indian Journal of Pediatrics — Tue, 31 Jan 2012 16:47:54 +0100

Abstract Hereditary Elliptocytosis is a heterogeneous group of disorder with regard to clinical presentation, protein defects and mode of inheritance. Parvoviral induced transient aplastic crisis in the form of sudden onset anemia is said to be a rare manifestation of this hereditary hemolytic anemia. The authors describe a case of parvoviral induced transient aplastic crisis in a patient with hereditary elliptocytosis and review the pathogenic mechanisms of parvoviral hemolytic disease. Content Type Journal ArticleCategory Clinical BriefPages 1-3DOI 10.1007/s12098-012-0684-1Authors Prasanna K. Kapavarapu, Department of Pediatrics, St. John’s Medical College and Hospital, St. John’s National Academy of Health Sciences, Sarjapur Road, Bangalore, IndiaAmal Paul, Depa...

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A DNA vaccine expressing PB1 protein of influenza A virus protects mice against virus infection

Archives of Virology — Tue, 31 Jan 2012 16:44:28 +0100

Abstract Although influenza DNA vaccine research has focused mainly on viral hemagglutinin and has led to promising results, other virion proteins have also shown some protective potential. In this work, we explored the potential of a DNA vaccine based on the PB1 protein to protect BALB/c mice against lethal influenza A virus infection. The DNA vaccine consisted of pTriEx4 plasmid expressing PB1. As a positive control, a pTriEx4 plasmid expressing influenza A virus HA was used. Two weeks after three subcutaneous doses of DNA vaccine, the mice were challenged intranasally with 1 LD50 of A/Puerto Rico/8/34 (H1N1) virus, and PB1- and HA-specific antibodies, survival rate, body weight change, viral mRNA load, infectious virus titer in the lungs, cytokines IL-2, IL-4 and IL-10, ...

Public Health Action Needed to Reduce Burdens of Chronic Illness

News from the National Academies — Tue, 31 Jan 2012 15:59:55 +0100

A new report from the Institute of Medicine says public health actions are urgently needed to tackle the vast and growing toll of chronic illness on individuals and society. The report’s recommendations focus on optimizing efforts to better understand the burden and needs of people with chronic diseases, improving the dissemination of effective community-based interventions and preventive clinical guidelines, promoting the testing of an aligned health system to help people live well with chronic illness, and promoting the creation and implementation of public health policies in emerging legislation. (Source: News from the National Academies)

Confession: this pediatrician is a sleep softie

Thrive, Children's Hospital Boston — Tue, 31 Jan 2012 14:13:35 +0100

This may not be a great confession to make as a pediatrician, but when it comes to sleep and kids, I am a total softie. Our kids slept in our bed. We slept in theirs (which was very cramped in the toddler bed, and didn’t do great things to the frame)—or lay next to them as they drifted off to sleep. We sat on the floor, telling stories and singing lullabies and slowly edging out of the bedroom as their breathing got deep and regular. We went in again and again to retrieve the stuffed animal from under the bed or to investigate the scary noise or possible spider. When they woke in the middle of the night, we held them until they went back to sleep—sometimes night after night. Our children have always had a reasonable bedtime (even if we ignore it sometimes), we’ve made sure their sl...

Scientists Transform Skin Cells Direct To Brain Cells, Bypassing Stem Cell Stage

Health News from Medical News Today — Tue, 31 Jan 2012 10:00:00 +0100

Bypassing the stem cell stage, researchers at the Stanford University School of Medicine in California converted mouse skin cells directly into neural precursor cells, the cells that go on to form the three main types of cell in the brain and nervous system. They write about their findings in the 30 January early online issue of the Proceedings of the National Academy of Sciences... (Source: Health News from Medical News Today)

Cone-rod dystrophy can be a manifestation of Danon disease

Graefe's Archive for Clinical and Experimental Ophthalmology — Tue, 31 Jan 2012 07:12:17 +0100

Conclusions This is the first description of CRD in Danon disease. The retinal phenotype was a late onset but severe dystrophy characterized by loss of photoreceptors and RPE cells. With this report, we highlight the importance of a comprehensive ophthalmologic examination in the clinical work-up of Danon disease. Content Type Journal ArticleCategory Case ReportPages 1-6DOI 10.1007/s00417-011-1857-8Authors Alberta A. H. J. Thiadens, Department of Ophthalmology, Erasmus Medical Center, P.O. Box 2040, NL-3000 CA, Rotterdam, NetherlandsNiki W. R. Slingerland, Department of Ophthalmology, Erasmus Medical Center, P.O. Box 2040, NL-3000 CA, Rotterdam, NetherlandsRalph J. Florijn, Departments of Clinical and Molecular Ophthalmogenetics, Netherlands Institute for Neuroscien...

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Transdifferentiation of human adipose-derived stem cells into urothelial cells: potential for urinary tract tissue engineering

Cell and Tissue Research — Tue, 31 Jan 2012 07:12:12 +0100

In conclusion, HADSCs showed in vitro the upregulation of markers for differentiation towards urothelial cells by culturing in an urothelial-conditioned medium, which provides an alternative cell source for potential use in urinary tract tissue engineering. Content Type Journal ArticleCategory Regular ArticlePages 1-10DOI 10.1007/s00441-011-1317-0Authors Jian-Guo Shi, Department of Urology, Chinese People’s Liberation Army General Hospital, Military Postgraduate Medical College, No.28 Fuxing Road, Hai dian District, Beijing, 100853 People’s Republic of ChinaWei-Jun Fu, Department of Urology, Chinese People’s Liberation Army General Hospital, Military Postgraduate Medical College, No.28 Fuxing Road, Hai dian District, Beijing, 100853 People’s Republic of ChinaXiao-Xiong Wan...

Osteoblastogenesis regulation signals in bone remodeling

Osteoporosis International — Tue, 31 Jan 2012 07:05:08 +0100

Abstract Bone remodeling is essential for adult bone homeostasis. The failure of this process often leads to the development of osteoporosis, a present major global health concern. The most important factor that affects normal bone remodeling is the tightly controlled and orchestrated regulation of osteoblasts and osteoclasts. The present review summarized the recent discoveries related to osteoblast regulation from several signals, including transforming growth factor-β, bone morphogenetic proteins, Wnt signal, Notch, Eph–Ephrin interaction, parathyroid hormone/parathyroid hormone-related peptide, and the leptin–serotonin–sympathetic nervous systemic pathway. The awareness of these mechanisms will facilitate further research that explores bone remodeling and osteop...

Lsuhsc's Gee helping address international medical education leadership void

EurekAlert! - Social and Behavioral Science — Tue, 31 Jan 2012 05:00:00 +0100

(Louisiana State University Health Sciences Center) Dr. Rebekah Gee, Assistant Professor at LSU Health Sciences Center New Orleans Schools of Public Health and Medicine, is the lead author of an article published in the Jan. 28, 2012 issue of the Lancet regarding the impending void in medical education leadership worldwide. Dr. Gee is the only US physician serving on the inaugural Inter Academy Medical Panel program held during the third World Health Summit in Berlin, Germany to address it. (Source: EurekAlert! - Social and Behavioral Science)

New cell-therapy technique may obviate stem-cell research

Physics Today News Picks — Tue, 31 Jan 2012 05:00:00 +0100

BBC: Researchers at Stanford University School of Medicine have succeeded in converting mouse skin cells into "neural precursor" cells, which can develop into three types of brain cell. The group's findings, which have been published in the Proceedings of the National Academy of Sciences, may be important for certain medical therapies, such as bone marrow transplants. Until now such transplants have relied on stem cells, which can divide and differentiate into many different specialized cell types. Stem-cell research has been hampered by ethical concerns, however, because one source of the cells has been human embryos. More work will have to be done to re-create the experiment using human skin cells. (Source: Physics Today News Picks)

Examining factors influencing patient satisfaction with nurse practitioners in rural urgent care centers

Journal of the American Academy of Nurse Practitioners — Tue, 31 Jan 2012 05:00:00 +0100

Conclusions: No statistical significance was noted in regards to patient satisfaction for the demographic factors age, gender, country of upbringing, or education level. Presence of health insurance was a significant factor, with uninsured patients rating higher levels of satisfaction. However, based on patients' responses to role clarity for this survey, it is evident that there continues to be insufficient public understanding of the role of NPs.Implications for practice: The future of the NP relies on patient approval as well as acceptance of the role. This study joins the pioneering efforts towards describing what patient satisfaction is and supports NPs serving as providers in rural, nonprimary care venues. By identifying influential factors of satisfaction, NPs can bridge the gap bet...

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A review of actinic keratosis for the nurse practitioner: Diagnosis, treatment, and clinical pearls

Journal of the American Academy of Nurse Practitioners — Tue, 31 Jan 2012 05:00:00 +0100

Conclusions: Actinic keratosis is a common skin lesion seen in primary care that results from exposure to ultraviolet light. Accurate and timely diagnosis is essential to prevent progression to squamous cell carcinoma.Implications for practice: Nurse practitioners can make a positive impact on patients' health by promoting treatment adherence and follow‐up in primary care. (Source: Journal of the American Academy of Nurse Practitioners)

Efficacy of Phototherapy for Newborns with Hyperbilirubinemia: A Cautionary Example of an Instrumental Variable Analysis

Medical Decision Making — Tue, 31 Jan 2012 05:00:00 +0100

Conclusions. Instrumental variable analyses may provide biased estimates of treatment efficacy if there are cointerventions or confounders associated with treatment at the level of the instrument, although even when these associations may not exist in individuals. (Source: Medical Decision Making)

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