MedWorm: Graduation

Discrepancies between knowledge and practice of childhood motor vehicle occupant safety in Nova Scotia-A population-based study.

Accident; Analysis and Prevention. — Wed, 08 Feb 2012 21:30:01 +0100

CONCLUSIONS: Discrepancies between knowledge and practice are evident through all stages of CMVRs, but most marked with booster seats. The roles of lower socioeconomic status and gaps in CMVR legislation, in influencing discrepant practice, must be acknowledged and suggest the need for targeted education concurrent with development of comprehensive all-stages CMVR policies. PMID: 22269516 [PubMed - in process] (Source: Accident; Analysis and Prevention.)

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Evaluation of a program to enhance young drivers' safety in Israel.

Accident; Analysis and Prevention. — Wed, 08 Feb 2012 21:20:54 +0100

Authors: Toledo T, Lotan T, Taubman-Ben-Ari O, Grimberg E Abstract Young drivers in Israel, as in other parts of the world, are involved in car crashes more than any other age group. The graduated driver licensing system in Israel requires that all new drivers be accompanied by an experienced driver whenever they drive for the first 3months after obtaining a driving license. In an effort to make the accompanied driving phase more effective, a novel program which targets both young drivers and their parents was initiated in 2005. The program administers a personal meeting with the young driver and the accompanying parent scheduled for the beginning of the accompanied driving phase. In this meeting guidance is given regarding best practices for undertaking the accompanied driving, as...

Denis Parsons Burkitt CMG, MD, DSc, FRS, FRCS, FTCD (1911–93) Irish by birth, Trinity by the grace of God

British Journal of Haematology — Wed, 08 Feb 2012 05:00:00 +0100

SummaryDenis Parsons Burkitt, surgeon and research scientist, is a household name in the medical profession. Denis received his BA in 1933 and graduated as a physician in 1935 from Trinity College, Dublin. After serving as a surgeon in the Royal Army Medicine Corps during World War II, he worked as a surgeon and lecturer in Africa. It was in Africa that he developed exceptional observational and analytical skills, which led him to identify and formally develop a successful treatment for a childhood cancer that is now called Burkitt Lymphoma. The influence of Christianity in his life was huge. Throughout his life he remained extremely modest, attributing much of what he had achieved to the work of others. Denis's contributions to haemato‐oncology remain salient today, and his discoveries ...

Pitt study: Drug costs, not volume, causes regional differences in Medicare drug spending

EurekAlert! - Medicine and Health — Wed, 08 Feb 2012 05:00:00 +0100

(University of Pittsburgh Schools of the Health Sciences) The cost of medications through Medicare's subsidized prescription drug program varies from region to region across the United States largely due to the use of more expensive brand-name drugs and not because of the amount of drugs prescribed, according to a study led by researchers from the University of Pittsburgh Graduate School of Public Health (GSPH). The authors said that more efficient prescribing practices could have saved the Medicare program and its beneficiaries $4.5 billion. (Source: EurekAlert! - Medicine and Health)

Is Presence of a Student-Run Clinic During Medical School Associated with Future Primary Care Practice? (Sebastian Tong Mr.)

Family Medicine Digital Resources Library (FMDRL) Recently Uploaded — Tue, 07 Feb 2012 05:00:00 +0100

This powerpoint presentation addresses whether there is an association between presence of a student-run clinic at a medical school and future practice of medical school graduates in a primary care specialty. A 2005 survey of all student-run clinics associated with medical schools was supplemented by direct survey of schools missing from this dataset. We used multiple linear regression to test associations controlling for medical school confounders. In 2005, 72 of 115 responding medical schools had student-run clinics. No association was found between having a student-run clinic at a medical school and proportion of its graduates who currently practice primary care. We will discuss implications and future directions for student-run clinic research. Please contact me (Sebastian Tong) by em...

Drink to a healthy old age... with green tea: How beverage helps people stay fit

the Mail online | Health — Tue, 07 Feb 2012 00:41:54 +0100

Those who drank the most green tea were the least likely to develop 'functional disability' according to the Tohoku University Graduate School of Medicine. (Source: the Mail online | Health)

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Craig Phelps to take over as A.T. Still president

bizjournals.com Health Care:Biotechnology headlines — Mon, 06 Feb 2012 21:33:30 +0100

Dr. Craig Phelps, who currently serves as senior vice president for strategic initiatives for A.T. Still University, has been promoted to president of the university. He will split his time between ATSU’s main campus in Kirksville, Mo., and its Mesa campus. He is replacing Jack Magruder, who announced his retirement several months ago. His new role becomes effective July 1. Phelps is a 1984 graduate of ATSU’s Kirksville College of Osteopathic Medicine. He became provost of its Arizona campus in 1998 and led the team that developed that campus and its three academic units — the Arizona School of Health Sciences, the Arizona School of Dentistry & Oral Health, and the School of Osteopathic Medicine in Arizona... (Source: bizjournals.com Health Care:Biotechnology headlines)

Green Tea Protects Against Functional Disability Linked To Aging

Health News from Medical News Today — Mon, 06 Feb 2012 21:00:00 +0100

Regular green tea drinkers have a lower risk of developing functional disability, researchers from Tohoku University Graduate School of Medicine, Sendai, Japan, reported in the American Journal of Clinical Nutrition. Functional disability refers to problems with daily chores and activities, such as bathing or dressing. As background information, the authors explained that prior studies had found that consuming green tea reduced the risk of diseases associated with functional disability, such as osteoporosis, cognitive impairment and stroke... (Source: Health News from Medical News Today)

A case of IgG4-related pulmonary disease with rapid improvement

Modern Rheumatology — Mon, 06 Feb 2012 19:35:26 +0100

We report a 72-year-old man with respiratory involvement of immunoglobulin G4 (IgG4)-related disease, who developed dry cough and shortness of breath on effort. The chest computed tomography scan image showed massive and diffuse ground-glass opacity, interlobular thickening, and bronchial wall thickening. The infiltration of IgG4-positive plasma cells in the transbronchial lung biopsy and high serum IgG4 concentrations were found. The patient was treated with 0.6 mg/kg oral prednisolone and showed rapid improvement. This is a case of IgG4-related disease in which the only complication was respiratory involvement. Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.1007/s10165-012-0600-6Authors Masataka Umeda, Department of Rheumatology, Isahaya Health Insurance ...

Evaluation of a program to enhance young drivers' safety in Israel. - Toledo T, Lotan T, Taubman-Ben-Ari O, Grimberg E.

SafetyLit: All (Unduplicated) — Mon, 06 Feb 2012 11:54:53 +0100

Young drivers in Israel, as in other parts of the world, are involved in car crashes more than any other age group. The graduated driver licensing system in Israel requires that all new drivers be accompanied by an experienced driver whenever they drive fo... (Source: SafetyLit: All (Unduplicated))

Students decide: Feeling mutual?

BMA daily feed — Mon, 06 Feb 2012 10:35:00 +0100

Should students on traditional medical degree courses subsidise graduate-entry medics? (Source: BMA daily feed)

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National Professional Science Master's Association Presents...

PRWeb: Medical Pharmaceuticals — Mon, 06 Feb 2012 06:00:14 +0100

“Preparing Graduates for Challenging and Rewarding Careers in the Biotechnology Industry”(PRWeb February 03, 2012)Read the full story at http://www.prweb.com/releases/2012/2/prweb9159630.htm (Source: PRWeb: Medical Pharmaceuticals)

Heavy smoking during pregnancy as a marker for other risk factors of adverse birth outcomes: a population-based study in British Columbia, Canada

BMC Public Health - Latest articles — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion: Our data suggests that self reports of heavy smoking early in pregnancy could be used as a marker for lifestyle risk factors that in combination with smoking influence birth outcomes. This information may be used for planning targeted intervention programs for not only smoking cessation, but potentially other support services such as nutrition and healthy pregnancy education. (Source: BMC Public Health - Latest articles)

[Correspondence] The Integrated Academic Training programme at Oxford

LANCET — Sat, 04 Feb 2012 05:00:00 +0100

In 2006, the Integrated Academic Training programme was initiated in the UK as a result of the Walport report on the crisis of decreasing clinical academic numbers. In Oxford, we decided that the most effective way to manage the programme would be to create a dedicated Oxford University Clinical Academic Graduate School ( OUCAGS). We wish to highlight both some advantages of this approach and challenges within the overall programme. (Source: LANCET)

Jacqueline Rose: a life in writing

Guardian Unlimited Science — Fri, 03 Feb 2012 22:55:08 +0100

'Victimhood is something that happens but when you turn it into an identity you're psychically and politically finished'One day, Jacqueline Rose came across a troubling passage in Proust's A la recherche du temps perdu. The narrator, Marcel, lies beside his sleeping lover Albertine and masturbates against her. "It seemed to me at those moments," writes Proust in Carol Clark's recent Penguin translation, "that I possessed her more completely, like an unconscious part of dumb nature." Professor Rose, feminist and psychoanalytic critic, bristled. "I thought 'This is ridiculous – she'd have woken up by now!' I had my feminist reaction – which is not my most obvious default position – which is just let the woman speak."So Rose decided to awaken Proust's lover from her implausible slumber....

Are Nuisance Jellyfish Really Taking Over the World's Oceans?

BioScience Press Releases — Fri, 03 Feb 2012 19:26:33 +0100

In recent years, media reports of jellyfish blooms and some scientific publications have fueled the idea that jellyfish and other gelatinous floating creatures are becoming more common and may dominate the seas in coming decades. The growing impacts of humans on the oceans, including overfishing and climate change, have been suggested as possible causes of this apparently alarming trend. A careful evaluation of the evidence by Robert H. Condon of Dauphin Island Sea Lab and his 16 coauthors, however, finds the idea that jellyfish, comb jellies, salps and similar organisms are surging globally to be lacking support. Rather, Condon and his colleagues suggest, the perception of an increase is the result of more scientific attention being paid to phenomena such as jellyfish blooms and media fa...

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Faculty Positions in Biology - University of Tabuk, Saudi Arabia

AIBS Classifieds — Fri, 03 Feb 2012 19:26:32 +0100

The Biology Department at the University of Tabuk in Saudi Arabia seeks applicants for multiple faculty positions in all fields of biology for both female and male campuses. Faculty positions are open at the Assistant, Associate, and Full Professor levels and commence in September 2012. Candidates must have an earned doctorate in Biology or a related field. Specific duties include the development of research programs, undergraduate and graduate teaching, student advisement, and service activities. Interested candidates are invited to submit a letter of application, a comprehensive current CV, and a summary of teaching and research interests. All materials should be sent electronically as a .pdf file to UofTabukBIO@yahoo.com The language of instruction at the University of Tabuk is Engli...

18F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas

European Journal of Nuclear Medicine and Molecular Imaging — Fri, 03 Feb 2012 17:51:36 +0100

Conclusion These preliminary data suggest that FMISO PET may distinguish GBM from lower grade gliomas. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00259-011-2037-0Authors Kenji Hirata, Department of Nuclear Medicine, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-Ku, Sapporo, Hokkaido 060-8638, JapanShunsuke Terasaka, Department of Neurosurgery, Graduate School of Medicine, Hokkaido University, Sapporo, JapanTohru Shiga, Department of Nuclear Medicine, Graduate School of Medicine, Hokkaido University, Kita 15, Nishi 7, Kita-Ku, Sapporo, Hokkaido 060-8638, JapanNaoya Hattori, Department of Molecular Imaging, Graduate School of Medicine, Hokkaido University, Sapporo, JapanKeiichi Magota, Department of Radiology, Ho...

Erratum to: Ethnic differences in composite indices of femoral neck strength

Osteoporosis International — Fri, 03 Feb 2012 17:11:21 +0100

Content Type Journal ArticleCategory ErratumPages 1-2DOI 10.1007/s00198-011-1887-4Authors S. Ishii, Geriatric Research, Education and Clinical Center (GRECC), VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Building 220, Room 302, Los Angeles, CA 90073, USAJ. A. Cauley, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, A524 Crabtree, Pittsburgh, PA 15260, USAG. A. Greendale, Department of Medicine/Division of Geriatrics, David Geffen School of Medicine at UCLA, 10933 Le Conte Ave, Los Angeles, CA 90095, USAM. E. Danielson, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, A524 Crabtree, Pittsburgh, PA 15260, USAN. Safaei Nili, Department of Medicine/Division ...

Evaluation of exercise capacity using wave intensity in chronic heart failure with normal ejection fraction

Heart and Vessels — Fri, 03 Feb 2012 07:22:08 +0100

In conclusion, W2 is considered to be clinically more useful than conventional TTE indices for evaluating exercise capacity in patients with chronic HFNEF. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00380-011-0224-3Authors Yoichi Takaya, Department of Cardiovascular Medicine, Okayama University Graduate School of Medicine, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558 JapanManabu Taniguchi, Division of Cardiac Intensive Care Unit, Okayama University Hospital, Okayama, JapanMotoaki Sugawara, Department of Medical Engineering, Himeji Dokkyo University, Himeji, JapanSaori Nobusada, Division of Central Clinical Laboratory, Okayama University Hospital, Okayama, JapanKengo Kusano, Department of Cardiovascular Medicine, Okayama University Graduate School of...

Should urologists care for the pharyngeal infection of Neisseria gonorrhoeae or Chlamydia trachomatis when we treat male urethritis?

Journal of Infection and Chemotherapy — Fri, 03 Feb 2012 07:22:04 +0100

Abstract Detection of Neisseria gonorrhoeae (NG) or Chlamydia trachomatis (CT) from the pharynx of women or men is not uncommon. However, there is no recommendation how urologists should care for the pharyngeal infection of men with urethritis in Japan. The aim of this study is to clarify the prevalence of NG or CT infection in the pharynx of men and to show a recommendation for urologists. The Japanese reports about the detection of NG or CT from the pharynx or the oral cavity of men in Japan are reviewed in the literature from 1990 to 2011. The prevalence of NG or CT in the pharynx was 4% or 6% in men who attended clinics, and 20% or 6% in men who were positive for NG or CT from genital specimens, respectively. Single 1-g dose ceftriaxone was recommended to treat pharynge...

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Computerized detection of lung nodules by CT for radiologic technologists in preliminary screening

Radiological Physics and Technology — Fri, 03 Feb 2012 07:19:35 +0100

Abstract In Japan, radiologists and radiologic technologists are endeavoring to improve the quality of lung CT screening. In particular, preliminary screening by radiologic technologists is expected to decrease radiologists’ burden and improve the accuracy of CT screening. We considered that an application of computer-aided detection (CAD) would also be as useful in preliminary screening as in the radiologist’s regular reading. Our purpose in this study was to investigate the potential of the application of CAD to preliminary screening. CAD software that we developed was applied to 17 lung CT scans that radiologic technologists had pre-interpreted. A radiologist recognized 29 lung nodules from the CT images, whereas radiologic technologists did not recognize 11 of the ...

AIBS names emerging public policy leaders

EurekAlert! - Social and Behavioral Science — Fri, 03 Feb 2012 05:00:00 +0100

(American Institute of Biological Sciences) The American Institute of Biological Sciences has selected two graduate students to receive the 2012 AIBS Emerging Public Policy Leadership Award. Lida Beninson is a Ph.D. candidate in Integrative Physiology at the University of Colorado Boulder. Andrew Reinmann is a Ph.D. candidate in Biology at Boston University. (Source: EurekAlert! - Social and Behavioral Science)

Fellowships to assist 9 UC Riverside students secure doctoral degrees

EurekAlert! - Biology — Fri, 03 Feb 2012 05:00:00 +0100

(University of California - Riverside) The University of California, Riverside has awarded nine first-year graduate students an annual stipend of $30,000 for two years to increase underrepresented minority students in the fields of Science, Technology, Engineering and Mathematics at the doctoral level. In addition to the stipend that covers living expenses, each student's graduate tuition and fees are fully covered. Because of the fellowships, the nine students will be fully engaged in research from the outset. (Source: EurekAlert! - Biology)

Prehospital trauma care reduces mortality. Ten-year results from a time-cohort and trauma audit study in Iraq

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine — Fri, 03 Feb 2012 05:00:00 +0100

Conclusion: In case of long prehospital transit times simple life support measures by paramedics and lay first responders reduce trauma mortality in major injuries. Delegating life-saving skills to paramedics and lay people is a key factor for efficient prehospital trauma systems in low-resource communities.. (Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine)

SFU scientists seek teaching excitement at AAAS

EurekAlert! - Social and Behavioral Science — Fri, 03 Feb 2012 05:00:00 +0100

(Simon Fraser University) Thousands of scientists, including many from SFU, will descend upon Vancouver, Feb. 16-20 to not only share research discoveries but also hone their skills as science educators. They will share their teaching trade secrets at the 2012 American Association for the Advancement of Science conference, known as the world's largest science fair. SFU's Faculty of Science is sponsoring 10 faculty members, two staff and two graduate students to attend the AAAS' symposium on education. (Source: EurekAlert! - Social and Behavioral Science)

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Recovery of visual function in patient with melanoma-associated retinopathy treated with surgical resection and interferon-beta

Documenta Ophthalmologica — Thu, 02 Feb 2012 18:16:47 +0100

We report on a 33-year-old woman who was treated for a cutaneous malignant melanoma on a left finger by surgical resection and chemotherapy including local injections of interferon-beta in 2007. In March 2009, the melanoma had metastasized to her left hand, and she underwent metastasectomy and monthly local injections of interferon-beta. She developed shimmering vision, photopsia, blurred vision, and night blindness in her left eye in April 2009 and visited our clinic. At our initial examination, her best-corrected visual acuity was 1.5 OD and 1.2 OS, and ophthalmoscopy showed that the retina appeared normal in both eyes. However, there was a mild narrowing of retinal arteries in the left eye. Humphrey field analyzer (HFA) showed a reduction in retinal sensitivity within the central ...

Endotracheal metastasis from basaloid squamous carcinoma of the esophagus

Esophagus — Thu, 02 Feb 2012 18:15:46 +0100

We describe a rare case of metachronous endotracheal metastasis originating from esophageal basaloid squamous carcinoma. A 72-year-old Japanese man underwent esophagectomy for stage I esophageal cancer. Pathological diagnosis of the resected specimen was basaloid squamous carcinoma. One year later, a follow-up computed tomography scan displayed a tumor shadow in the tracheal wall. Bronchoscopy revealed a protruding tumor in the tracheal wall, and the pathologic diagnosis of the biopsy specimen was also basaloid squamous carcinoma. According to the diagnosis of metachronous endobronchial metastasis from esophageal basaloid squamous carcinoma, we treated the patient with chemotherapy comprising docetaxel, cisplatin, and 5-fluorouracil followed by chemoradiotherapy, and complete respons...

The Relationship of Lymph Node Evaluation and Colorectal Cancer Survival After Curative Resection: A Multi-Institutional Study

Annals of Surgical Oncology — Thu, 02 Feb 2012 18:12:37 +0100

Conclusion This study found that the number of lymph nodes retrieved and the number of positive nodes are both important prognostic factors. At least a 12-node threshold may be supported as a measure to improve a predictive capacity within individual patients and as a quality control parameter of hospital performance. Content Type Journal ArticleCategory Colorectal CancerPages 1-9DOI 10.1245/s10434-012-2223-8Authors Yukihide Kanemitsu, Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, JapanKoji Komori, Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, JapanSeiji Ishiguro, Department of Gastroenterological Surgery, Aichi Cancer Center, Nagoya, JapanToshiaki Watanabe, Department of Surgery, Teikyo University School of Medici...

Clinicopathological Profile, Airway Management, and Outcome in Huge Multinodular Goiters: An Institutional Experience from an Endemic Goiter Region

World Journal of Surgery — Thu, 02 Feb 2012 18:12:35 +0100

Conclusions Long-standing huge goiters are common in iodine-deficient endemic areas. The majority of patients have symptomatic or clinicoradiological evidence of airway involvement. The incidence of RSE, airway deformity, intubation difficulty, and tracheomalacia is high with huge goiters. The surgery is technically demanding with greater associated chances of injury to native structures. Malignancy influences the presentation and outcome in smaller goiters. In centers with experienced endocrine surgeons and dedicated anesthetists, huge goiters can be successfully managed with minimal short-term and long-term morbidity. Content Type Journal ArticlePages 1-6DOI 10.1007/s00268-012-1447-xAuthors Amit Agarwal, Department of Endocrine Surgery, Sanjay Gandhi Post Gradua...

Low birth weight and end-stage renal disease: demographic analysis by region in Japan

Clinical and Experimental Nephrology — Thu, 02 Feb 2012 18:12:09 +0100

Conclusions The present study, relating regional distribution between LBW and ESRD dynamics in a nationwide population of Japan, revealed that the marked regional differences in the incidence of ESRD within Japan could be explained by a similar regional distribution in the incidence of LBW. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s10157-012-0600-zAuthors Tadashi Ichikawa, Department of Cardio-Renal Medicine and Hypertension, Nagoya City University, Graduate School of Medical Sciences, Mizuho-ku, Nagoya, 467-8601 JapanMichio Fukuda, Department of Cardio-Renal Medicine and Hypertension, Nagoya City University, Graduate School of Medical Sciences, Mizuho-ku, Nagoya, 467-8601 JapanTamaki Wakamatsu-Yamanaka, Department of Cardio-Renal Me...

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Post injury changes in the properties of mesenchymal stem cells derived from human anterior cruciate ligaments

International Orthopaedics — Thu, 02 Feb 2012 18:10:13 +0100

Conclusions Our results suggest that colony-forming and differentiation potential decrease over time. It is important to consider changes in properties of MSCs and use ACL tissue in the acute phase of rupture when biological manipulation is required. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00264-012-1484-yAuthors Shuya Nohmi, Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562 JapanYuji Yamamoto, Department of Orthopaedic Surgery, Hirosaki University Graduate School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562 JapanHiroki Mizukami, Department of Pathology and Molecular Medicine, Hirosaki University School of Medicine, 5 Zaifu-cho, Hirosaki, 036-8562 JapanYasuyuki Ishibash...

Interleukin-1β enhances the production of soluble MICA in human hepatocellular carcinoma

Cancer Immunology, Immunotherapy — Thu, 02 Feb 2012 17:58:29 +0100

In this study, we investigated the immunoregulatory role of IL-1β in the production of soluble MICA of HCC cells. First, we investigated the correlation between the serum IL-1β levels and soluble MICA in CH patients. Serum IL-1β levels were associated with soluble MICA levels in CH patients. The serum IL-1β levels of CH patients with the HCC occurrence were significantly higher than those of CH patients without HCC. We next examined the MICA production of IL-1β-treated HCC cells. Addition of IL-1β resulted in significant increase in the production of soluble MICA in HepG2 and PLC/PRF/5 cells, human HCC cells. But soluble MICA was not detected in both non-treated and IL-1β-treated normal hepatocytes. Addition of IL-1β did not increase the expressions of membrane-bound MICA on ...

Accuracy and measures of association of anthropometric indexes of obesity to identify the presence of hypertension in adults: a population-based study in Southern Brazil

European Journal of Nutrition — Thu, 02 Feb 2012 17:57:43 +0100

Conclusions Anthropometric indexes provide an effective, simple, inexpensive, and non-invasive means for a first-level screening for hypertension. Content Type Journal ArticleCategory Original ContributionPages 1-10DOI 10.1007/s00394-012-0314-8Authors Diego Augusto Santos Silva, Programa de Pós Graduação em Educação Física, Centro de Desportos, Universidade Federal de Santa Catarina, Campus Universitário Trindade, Florianópolis, SC CEP 88010-970, BrazilEdio Luiz Petroski, Post-Graduation Program in Physical Education, Federal University of Santa Catarina, Florianópolis, BrazilMarco Aurelio Peres, Post-Graduation Program in Public Health, Federal University of Santa Catarina, Florianópolis, Brazil Journal European Journal of NutritionOnline ISSN 1436-621...

A replacement for islet equivalents with improved reliability and validity

Acta Diabetologica — Thu, 02 Feb 2012 17:54:28 +0100

In conclusion, normalizing islet volume by IE overestimated the tissue volume, which may lead to erroneous results. Normalizing by cell number is a more accurate method to quantify tissue amounts used in islet transplantation and research. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00592-012-0375-4Authors Han-Hung Huang, Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, MS 2002, 3901 Rainbow Blvd., Kansas City, KS 66160, USAKarthik Ramachandran, Bioengineering Graduate Program, University of Kansas, School of Engineering, Lawrence, KS 66045, USALisa Stehno-Bittel, Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, MS 2002, 3901 Rainbow Blvd., Kansas City, KS ...

Exposing the Hidden Curriculum Influencing Medical Education on the Health of Indigenous People in Australia and New Zealand: The Role of the Critical Reflection Tool

Academic Medicine — Thu, 02 Feb 2012 14:12:24 +0100

The disparity in health status between Indigenous and non-Indigenous people in Australia and New Zealand is widely known, and efforts to address this through medical education are evidenced by initiatives such as the Committee of Deans of Australian Medical Schools' Indigenous Health Curriculum Framework. These efforts have focused primarily on formal curriculum reform. In this article, the authors discuss the role of the hidden curriculum in influencing the teaching and learning of Indigenous health (i.e., the health of Indigenous people) during medical training and suggest that in order to achieve significant changes in learning outcomes, there needs to be better alignment of the formal and hidden curriculum. They describe the Critical Reflection Tool as a potential resource through whic...

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Primary MALT lymphoma of the urinary bladder in the background of interstitial cystitis

Annals of Hematology — Thu, 02 Feb 2012 06:56:37 +0100

Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00277-012-1419-0Authors Ken Morita, Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655 JapanFumihiko Nakamura, Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655 JapanYasuhito Nannya, Department of Hematology and Oncology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655 JapanAkira Nomiya, Department of Urology, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655 JapanShunya Arai, Department of Hematology and Oncology, Graduate School of Medicine, The University...

Dietary Wolffia arrhiza meal as a substitute for soybean meal: its effects on the productive performance and egg quality of laying Japanese quails

Tropical Animal Health and Production — Thu, 02 Feb 2012 06:55:44 +0100

In conclusion, WAM could be successfully used in place of SBM. However, the amount used should not exceed 16.0%. Content Type Journal ArticleCategory Original ResearchPages 1-8DOI 10.1007/s11250-012-0091-7Authors Tawadchai Suppadit, The Graduate School of Social and Environmental Development, National Institute of Development Administration, Bangkapi District, Bangkok, 10240 ThailandSanchai Jaturasitha, Department of Animal Science, Faculty of Agriculture, Chiang Mai University, Muang District, Chiang Mai, 50200 ThailandNapassawan Sunthorn, Thailand Institute of Scientific and Technological Research, Khlong Luang, Pathum Thani 12120, ThailandPukkapong Poungsuk, Department of Agricultural Education, Faculty of Industrial Education, King Mongkut’s Institute of Technology Ladkrabang,...

Impact of diabetes and glycaemic control on peripheral artery disease in Japanese patients with end-stage renal disease: long-term follow-up study from the beginning of haemodialysis

Diabetologia — Thu, 02 Feb 2012 06:55:33 +0100

Conclusions/interpretation Diabetes was a strong predictor of PAD after initiation of haemodialysis therapy in patients with ESRD. In addition, higher HbA1c levels were associated with increased risk of developing PAD and requiring limb amputation in such diabetic populations. Content Type Journal ArticleCategory ArticlePages 1-6DOI 10.1007/s00125-012-2473-9Authors H. Ishii, Department of Cardiology, Nagoya University Graduate School of Medicine, 65, Tsurumai-cho, Showa-ku, Nagoya, 466-8550 JapanY. Kumada, Department of Cardiology, Nagoya Kyoritsu Hospital, Nagoya, JapanH. Takahashi, Department of Cardiology, Nagoya Kyoritsu Hospital, Nagoya, JapanT. Toriyama, Department of Cardiology, Nagoya Kyoritsu Hospital, Nagoya, JapanT. Aoyama, Department of Cardiology, Nagoya...

Increased serum soluble CD147 levels in patients with systemic sclerosis: association with scleroderma renal crisis

Clinical Rheumatology — Thu, 02 Feb 2012 06:55:21 +0100

This study aimed to determine serum soluble CD147 (sCD147) levels and their clinical associations in patients with systemic sclerosis (SSc). Serum sCD147 levels were examined by enzyme-linked immunosorbent assay in 61 SSc patients and 24 healthy individuals. Serum sCD147 levels were significantly elevated in SSc patients compared with healthy individuals (P < 0.001). Among patients with SSc, there were no differences in serum sCD147 levels between limited cutaneous (n = 30) and diffuse cutaneous SSc (n = 31). Patients with SSc who had elevated sCD147 levels had renal crisis more often than those with normal sCD147 levels (13% vs 0%; P < 0.05). Serum sCD147 levels were increased in patients with SSc and associated with the presence of renal crisis. These results s...

Neurological deficits in a patient with selenium deficiency due to long-term total parenteral nutrition

Journal of Neurology — Thu, 02 Feb 2012 06:54:08 +0100

Content Type Journal ArticleCategory Letter to the EditorsPages 1-2DOI 10.1007/s00415-012-6427-4Authors Takuya Oguri, Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-ku, Nagoya, 467-8601 JapanManabu Hattori, Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-ku, Nagoya, 467-8601 JapanTakemori Yamawaki, Department of Neurology and Neuroscience, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-ku, Nagoya, 467-8601 JapanSatoshi Tanida, Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-ku, Nagoya, 467-8601 JapanMakoto Sasaki, Department of Gastr...

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[Implementation of the new German job role code and its application in claims data analysis : Possibilities and limitations].

Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz — Wed, 01 Feb 2012 05:00:00 +0100

[Implementation of the new German job role code and its application in claims data analysis : Possibilities and limitations]. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2012 Feb;55(2):238-44 Authors: Damm K, Lange A, Zeidler J, Braun S, Graf von der Schulenburg JM Abstract In recent years, claims data analyses have become of increasing importance in several scientific disciplines in Germany. In specific research projects, it can be necessary to refine and to standardize the results by socioeconomic data. Information about graduation, social status, and occupation are provided by the German job role code for all people insured by statutory health insurance. During recent years, the working scheme has changed and new professions have appeared. Therefore, t...

Residency Training Oversight(s) in Surgery: The History and Legacy of the Accreditation Council for Graduate Medical Education Reforms.

The Surgical Clinics of North America — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Nauta RJ Abstract Despite a quarter century of discourse since a sentinel event in New York City raised the question of appropriate oversight for graduate medical education, many questions remain unanswered. Even with the Accreditation Council for Graduate Medical Education rules in place, some opportunity remains to examine handoff methodology, the relationship of duty hours to education, and the impact of fatigue on resident performance. Neurophysiologic adjuncts applied concomitantly to evaluation of didactic performance offer promise for data-driven definition of the optimal shift. Concurrently, the merits of specialty-specific oversight of graduate medical education remain under active consideration. PMID: 22269265 [PubMed - in process] (Source: The Surgical Clini...

Randomized controlled trial of a new portable calf compression device (Venowave) for prevention of venous thrombosis in high‐risk neurosurgical patients

Journal of Thrombosis and Haemostasis — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Venowave devices are effective in preventing VTE in high‐risk neurosurgical patients. (Source: Journal of Thrombosis and Haemostasis)

A Rural Health Service Learning Elective (Rita Lahlou)

Family Medicine Digital Resources Library (FMDRL) Recently Uploaded — Wed, 01 Feb 2012 05:00:00 +0100

Although many curricula are designed to increase student interest in primary care, few have been evaluated with regard to participants' final specialty choice, controlling for characteristics known to predict primary care practice. This session will describe an elective designed to foster interest in primary care, in which second year medical students manage operations at a free clinic, establish a continuity relationship with patients, attend a class covering primary care topics, keep a reflective journal, and complete a community project. We evaluated the impact of this course by surveying a sample of 257 alumni who graduated between 2003 and 2007. After adjustment for characteristics known to be associated with specialty choice, course participants were 5.5 times more likely than contro...

Quantitatively and Qualitatively Augmenting Medical Student Knowledge of Oncology and Radiation Oncology: An Update on the Impact of the Oncology Education Initiative

Journal of the American College of Radiology : JACR — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: In the successive years since its inception, the Oncology Education Initiative continues to show a significant improvement in medical students' knowledge of cancer. The initiative has also succeeded in providing radiation oncology education to all graduating medical students at the authors' institution. Dedicated oncology education in the undergraduate medical curriculum provides students with a better understanding of multidisciplinary oncology management. (Source: Journal of the American College of Radiology : JACR)

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JACR Journal Club: The University of Iowa Experience

Journal of the American College of Radiology : JACR — Wed, 01 Feb 2012 05:00:00 +0100

Residency programs are designed to take medical students and turn them into capable, practicing physicians. For most diagnostic radiology residents, that usually means becoming private practice or academic radiologists. The vast majority of didactics are focused on diagnosis. Most programs are proficient at teaching things such as how to work up an adrenal lesion, and the ABR tests residents to make sure they are safe. However, are graduating residents fully prepared to jump out of the nest? (Source: Journal of the American College of Radiology : JACR)

Prediction of Postinjury Employment and Percentage of Time Worked After Spinal Cord Injury

Archives of Physical Medicine and Rehabilitation — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: The factors precipitating PE are not identical to those associated with a greater portion of time employed after SCI onset. (Source: Archives of Physical Medicine and Rehabilitation)

Experiments combining communication with punishment options demonstrate how individuals can overcome social dilemmas.

The Behavioral and Brain Sciences — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Ostrom E Abstract Guala raises important questions about the misinterpretation of experimental studies that have found that subjects engage in costly punishment. Instead of positing that punishment is the solution for social dilemmas, earlier research posited that when individuals facing a social dilemma agreed on their own rules and used graduated sanctions, they were more likely to have robust solutions over time. PMID: 22289323 [PubMed - in process] (Source: The Behavioral and Brain Sciences)

A review of continuing professional development for dentists in Europe

European Journal of Dental Education — Wed, 01 Feb 2012 05:00:00 +0100

Conclusion: To ensure high standards of care, alongside recommending core or mandatory topics, more attention should be given to reflection on learning needs, the learner’s readiness to engage with education and training and the influence of the workplace environment. (Source: European Journal of Dental Education)

Mastering improvement science skills in the new era of quality and safety: the Veterans Affairs National Quality Scholars Program

Journal of Evaluation in Clinical Practice — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions The VA National Quality Scholars program continues to nurture and develop leaders for the new millennium focusing on interprofessional education. The nations' health care systems need strong interdisciplinary leaders in advanced quality improvement science who are dedicated to improving the overall quality of health and health care. (Source: Journal of Evaluation in Clinical Practice)

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Problem based learning in mental health nursing: The students' experience

International Journal of Mental Health Nursing — Wed, 01 Feb 2012 05:00:00 +0100

ABSTRACTProblem based learning (PBL) is well established within the field of health‐care education for professionals worldwide, although little has been done to explore the experiences of students undertaking a PBL course in mental health nursing. Without firm evidence of the benefits of PBL, educationalists in mental health might be reluctant to view it as an option in curricula design. This UK study examined the experiences of pre‐registration post‐graduate mental health student nurses undertaking a 2‐year educational course in which all teaching and assessment followed a PBL philosophy. Focus groups were used throughout the course to elicit in‐depth qualitative data that was analysed by applying a constant comparative method. The analysis of the data uncovered the following br...

Effect of heterozygous deletion of WNK1 on the WNK-OSR1/SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels

Clinical and Experimental Nephrology — Tue, 31 Jan 2012 16:47:51 +0100

Conclusion The contribution of WNK1 to total WNK kinase activity in the kidney may be small, but that WNK1 may play a substantial role in the regulation of blood pressure in the arteries. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s10157-012-0590-xAuthors Koichiro Susa, Department of Nephrology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Yushima 1-5-45, Bunkyo-ku, Tokyo, 113-0034 JapanSatomi Kita, Department of Pharmacology, School of Medicine, Fukuoka University, Fukuoka, JapanTakahiro Iwamoto, Department of Pharmacology, School of Medicine, Fukuoka University, Fukuoka, JapanSung-Sen Yang, Division of Nephrology, Department of Medicine, Tri-Service General Hospital, Taipei, TaiwanShih-Hua Lin, ...

Now in BioScience: "Will Lawmakers Reform Immigration Rules for STEM Graduates?"

Public Policy Reports — Tue, 31 Jan 2012 12:37:03 +0100

Increasingly, foreign-born students who pursue an advanced degree in a scientific field are choosing to leave the United States after graduation. This outflow concerns lawmakers from both sides of the political spectrum. The possibility of immigration reform is evaluated in the Washington Watch column in the January 2012 issue of BioScience. An excerpt from the article, “Will Lawmakers Reform Immigration Rules for STEM Graduates?,” follows: Ranjini Prithviraj is at the start of a promising career in neuroscience. She is a postdoctoral fellow at the National Institutes of Health (NIH), serves as an editor on the NIH Fellows Editorial Board, and mentors students interested in careers in science. Despite her strong résumé and her PhD in cell and molecular biology from a well-re...

Relationship between retinal morphological findings and visual function in age-related macular degeneration

Graefe's Archive for Clinical and Experimental Ophthalmology — Tue, 31 Jan 2012 07:12:16 +0100

Conclusions In eyes with exudative AMD, final VA was most correlated with initial VA. In addition, the initial integrity of the foveal outer retina was partially correlated with the visual prognosis. The initial ELM condition was associated with good final VA, while the initial presence of hyperreflective foci in the foveal neurosensory retina was associated with poor final VA. Content Type Journal ArticleCategory Retinal DisordersPages 1-8DOI 10.1007/s00417-012-1928-5Authors Yumiko Akagi-Kurashige, Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507 JapanAkitaka Tsujikawa, Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Sakyo-ku, Kyoto, 606-8507 Japan...

Significance of Lymph Node Capsular Invasion in Esophageal Squamous Cell Carcinoma

Annals of Surgical Oncology — Tue, 31 Jan 2012 07:11:04 +0100

Conclusions LNCI in ESCC patients is an indicator of distant organ recurrence and a worse prognosis. LNCI could be used as a candidate marker for designing more precise staging and therapeutic strategies for ESCC. Content Type Journal ArticleCategory Gastrointestinal OncologyPages 1-7DOI 10.1245/s10434-012-2232-7Authors Makoto Sakai, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, JapanShigemasa Suzuki, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, JapanAkihiko Sano, Department of General Surgical Science, Gunma University, Graduate School of Medicine, Maebashi, JapanNaritaka Tanaka, Department of General Surgical Science, Gunma University, Graduate School of Medicine,...

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A successful rescue with extra-anatomical bypass for massive bleeding of the brachiocephalic artery following salvage pharyngo-esophagectomy

Esophagus — Tue, 31 Jan 2012 07:07:17 +0100

Abstract Massive bleeding from large vessels is a serious and life-threatening complication after radical esophagectomy. Here, we present the rare case of patient survival following two episodes of massive bleeding from a tracheo-brachiocephalic artery fistula after salvage surgery for cervical esophageal cancer following definitive chemoradiation. During the first episode of bleeding, the damaged part of the brachiocephalic artery was transected with an extra-anatomical arterial bypass (right femoro-axillo artery bypass graft) to maintain the arterial blood flow to the brain and the free jejunal graft. During the second bleeding, the distal stump of the brachiocephalic artery was reclosed. During both episodes of bleeding, the musculocutaneous flap was effectively employe...

Laparoscopic management of complicated urachal remnants in adults

World Journal of Urology — Tue, 31 Jan 2012 07:06:01 +0100

Conclusion A laparoscopic approach with the removal of urachal remnants via the umbilicus appears to be a safe and effective alternative with better cosmesis when compared to an open approach. Content Type Journal ArticleCategory Original ArticlePages 1-4DOI 10.1007/s00345-012-0829-xAuthors Motoo Araki, Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558 JapanTakashi Saika, Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama, 700-8558 JapanDaiji Araki, Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikat...

Corporeity and social representations: acting and thinking about teaching

Psicologia e Sociedade — Mon, 30 Jan 2012 08:36:33 +0100

Este estudo procurou refletir sobre as manifestações corporais do professor e as representações construídas sobre sua profissão. Participaram da pesquisa estudantes de pedagogia e estudantes de pós-graduação em gestão escolar. Os sujeitos examinaram três fotografias extraídas de uma dinâmica de grupo onde pessoas representavam os papéis de professores. Eles foram requisitados a apontar dentre as figuras quais eram reais professores e a justificar as respostas. Com esta metodologia, foi possível identificar quais manifestações corporais foram identificadas como típicas de ser professor. Percebeu-se que os julgamentos baseados nas fotografias refletiam as formas de interação professor-aluno. Para os graduandos em pedagogia, a palavra "postura" e descrições de gestos ind...

New Findings On Aging Pediatric Bruises Published By Notre Dame Researchers

Health News from Medical News Today — Mon, 30 Jan 2012 08:00:00 +0100

A multi-university research group which includes several University of Notre Dame faculty and graduate students, has recently published a paper detailing new work on the analysis and dating of human bruises. The research, which is funded by the Gerber Foundation, will have particular application to pediatric medicine, as bruise age is often key evidence in child abuse cases... (Source: Health News from Medical News Today)

Leukemia Cells Are "Bad To The Bone"

Health News from Medical News Today — Mon, 30 Jan 2012 08:00:00 +0100

University of Rochester Medical Center researchers have discovered new links between leukemia cells and cells involved in bone formation, offering a fresh perspective on how the blood cancer progresses and raising the possibility that therapies for bone disorders could help in the treatment of leukemia. The research, led by graduate student Benjamin J. Frisch in the James P. Wilmot Cancer Center laboratory of corresponding author Laura M. Calvi, M.D., is featured in the journal Blood... (Source: Health News from Medical News Today)

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Localized pleural amyloidosis: report of a case

Surgery Today — Mon, 30 Jan 2012 06:32:13 +0100

Abstract We herein describe an asymptomatic 31-year-old male who was admitted for an investigation of an abnormal pleural tumor detected by chest radiography. We performed various preoperative investigations including fluorodeoxyglucose-positron emission tomography. The maximum standardized uptake value (SUVmax) was 2.2, and malignancy could not be ruled out. We therefore carried out a thoracoscopy-assisted partial resection of the right upper lobe combined with a parietal pleurectomy. The pathological examination showed that there was a tumor localized with pleural amyloidosis. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00595-012-0122-zAuthors Shohei Yoshiya, Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu Uni...

Impact of surgical site infection after colorectal surgery on hospital stay and medical expenditure in Japan

Surgery Today — Mon, 30 Jan 2012 06:32:12 +0100

Conclusions SSI clearly prolonged the hospital stay and increased medical costs. The numerical values revealed by this study reinforce the medical-economic importance of instigating preventive measures against SSI. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00595-012-0126-8Authors Nobuichi Kashimura, Department of Surgery, Teine Keijinkai Hospital, 1-12 Maeda Teine-ku, Sapporo, 006-8555 JapanShinya Kusachi, Department of Surgery, Toho University, Medical Center Ohashi Hospital, Tokyo, JapanToshiro Konishi, Department of Surgery, NTT Medical Center Tokyo, Tokyo, JapanJunzo Shimizu, Department of Surgery, Toyonaka Municipal Hospital, Toyonaka, JapanMasato Kusunoki, Department of Gastrointestinal and Pediatric Surgery, Mie University Grad...

Discrepancy of in-vitro data and clinical efficacy of micafungin against Candida tropicalis endophthalmitis

Journal of Infection and Chemotherapy — Mon, 30 Jan 2012 06:32:03 +0100

We report findings for a 74-year-old woman with Candida tropicalis endophthalmitis for whom an increase in β-d-glucan level and worsening of endophthalmitis were observed after intravenous injection of micafungin, an echinocandin antifungal agent. Endogenous endophthalmitis caused by C. tropicalis developed in both eyes. On the basis of her surgical history, laboratory data, and lesions, tentative diagnosis of fungal endophthalmitis was made. She was then treated with fluconazole and itraconazole, but the β-d-glucan level did not decrease, and there was no improvement of the endophthalmitis. The fluconazole was discontinued and replaced by micafungin. Unexpectedly, the level of β-d-glucan increased and endophthalmitis did not improve. The micafungin was immediately stopped and replac...

National Academy Workshop Explores Challenges Facing Chemistry Graduate Education

Chemical and Engineering News — Mon, 30 Jan 2012 06:00:17 +0100

(Source: Chemical and Engineering News)

Prescribing and the core curriculum for tomorrow's doctors: BPS Curriculum in Clinical Pharmacology and Prescribing for Medical Students

British Journal of Clinical Pharmacology — Mon, 30 Jan 2012 05:00:00 +0100

SummaryPrescribing is one of the commonest tasks expected of new doctors and is a complex process involving a mixture of knowledge, judgement and skills. Preparing graduates to be prescribers is one of the greatest challenges of modern undergraduate medical education and there is some evidence to suggest that training could be improved. The aims of this article are (i) to review some of the challenges of delivering effective prescribing education, (ii) to provide a clear statement of the learning outcomes in clinical pharmacology and prescribing that should be expected of all medical graduates, and (iii) to describe a curriculum that might enable students to achieve these outcomes. We build on the previous curriculum recommendations of the British Pharmacological Society and take into acco...

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International Collaboration and graduate programs in nursing administration

Revista da Escola de Enfermagem da USP — Mon, 30 Jan 2012 03:57:48 +0100

(Source: Revista da Escola de Enfermagem da USP)

The setting of research production by nursing and management graduate programs in Brazil

Revista da Escola de Enfermagem da USP — Mon, 30 Jan 2012 03:57:48 +0100

Trata-se de um estudo documental, descritivo, com abordagem quantitativa, com o objetivo de caracterizar a produção da pós-graduação brasileira na área da enfermagem no triênio 2007-2009, com ênfase na temática gerenciamento em enfermagem. As informações foram obtidas no banco de dados da CAPES, que disponibiliza resumos de dissertações e teses. O material foi analisado e categorizado segundo as áreas/campos e respectivas linhas de pesquisa, definidas pela área de Enfermagem. A análise da produção em geral foi descritiva e analítica/crítica no campo organizacional, especificamente, na temática do gerenciamento. Os resultados mostraram algumas mudanças na produção no triênio, quando comparada aos estudos anteriores, destacando-se o crescimento da área/campo assiste...

The profile of nursing management graduates from the nursing programs in southern Brazil

Revista da Escola de Enfermagem da USP — Mon, 30 Jan 2012 03:57:48 +0100

The objective was to describe the profile of graduates from the Nursing Graduate Programs from Southern Brazil, from 2006 to 2009, which titles revealed they were in the lines of research regarding nursing management. The data was collected using The CAPES Indicator Books and searches on the graduates' Curriculum Lattes/CNPq. The Nursing Graduate Programs in Southern Brazil totaled 409 students, 129 (31.5%) of which worked in the lines of research associated with nursing management/administration: 116 (89.9%) Masters and 13 (10.1%) Doctorates. Most graduates currently work as faculty. Of those with a master degree, two (1.7%) have already obtained a doctorate degree, and 39 (33.6%) are currently in the doctorate program. The intellectual production after obtaining the degree adds up to 501...

The professional profile of UFBA nursing management graduate students

Revista da Escola de Enfermagem da USP — Mon, 30 Jan 2012 03:57:48 +0100

The objective of the present study was to analyze the professional profile of the nursing graduate students of Federal University of Bahia, more specifically of the nursing management area. This descriptive, exploratory study was performed using documental research. The data was collected from the graduates' curriculum on the Lattes Platform and from the graduate program documents, using a form. The study population consisted of graduates enrolled under the line of research The Organization and Evaluation of Health Care Systems, who developed dissertations/theses addressing Nursing/Health Management. The data were stored using Microsoft Excel, and then transferred to the STATA 9.0 statistical software. Results showed that most graduates are women, originally from the State of Bahia, and ha...

The profile of EEUSP graduates of the stricto sensu program in nursing management

Revista da Escola de Enfermagem da USP — Mon, 30 Jan 2012 03:57:48 +0100

The objectives of the present study were to identify and discuss on the profile of the graduates form the stricto sensu program in Nursing Administration/Management of the University of São Paulo School of Nursing, from October 2008 to June 2011, regarding the knowledge areas the graduates worked on during their master and doctoral program. This is an exploratory, descriptive, retrospective study, using documental analysis. The study population consisted of 250 graduates, 169 of which were masters and 81 doctorates. The graduates' profile permitted to identify and discuss on the retention rate for the doctorate; the type of institution that absorbs the master and doctorate graduate and the fields they work in.El presente estudio tuvo como objetivos identificar y discutir el perfil de egre...

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A Few Minutes With Sharon Chappy

AORN Journal — Mon, 30 Jan 2012 03:56:37 +0100

I am currently the graduate program director and assistant dean in the College of Nursing at the University of Wisconsin Oshkosh. Before going back to school to obtain my master's degree in nursing and my doctorate, I was a perioperative staff nurse and manager for more than 10 years. After I started teaching in 1993, I continued to work as a perioperative nurse during summer months and school breaks. That connection to practice made me a better and more respected educator. Perioperative nursing is my passion, and I have influenced many students to go on to become perioperative nurses. I am an avid researcher and writer, and I won the AORN Journal Writers Contest Award for research twice (2005 and 2007). I have chaired two AORN national committees: the Scholarship Board (2005-2006) and the...

In memoriam

AORN Journal — Mon, 30 Jan 2012 03:56:37 +0100

Elouise Hardy passed away August 20, 2011, in Norwalk, Ohio. Hardy was a graduate of St Luke's Hospital School of Nursing in Cleveland, and she worked as a nurse at the Fisher Titus Medical Center in Norwalk for 25 years before retiring in 1995. She joined AORN in 1973 and was a charter member of the Ohio State Council. She was active in the AORN National Legislative Committee for many years and was profiled in Members Making a Difference in the February 2009 issue of AORN Connections for her grassroots political efforts in promoting RN circulator legislation for the state of Ohio. She was quoted as saying, “Every nurse needs to know what is going on with health care reform and legislation, and the best way to do that is to be an AORN legislative grassroots member.” Hardy was also a fo...

Shy Girl, Brave Woman

Psychology Today Anxiety Center — Sat, 28 Jan 2012 01:43:37 +0100

As a psychologist, I am frequently inspired by the resiliency people display in everyday life. Through the Internet and the power of social networking, I have met amazing people whose stories need to be told. Let me introduce you to Marla Genova, a woman who has worked hard to confront her own social anxiety, and ultimately, help others do the same.read more (Source: Psychology Today Anxiety Center)

The Role of Social Support and Acculturative Stress in Health-Related Quality of Life Among Day Laborers in Northern San Diego

Journal of Immigrant and Minority Health — Fri, 27 Jan 2012 17:55:48 +0100

Abstract There is evidence to suggest that Latino day laborers experience higher levels of acculturative stress than Latinos in employment sectors in the US. Given the stress-buffering role that social support plays in minimizing the negative physical and mental health outcomes of stress, this study examined this relationship in a sample of 70 Latino Day laborers in the northern San Diego area (100% male, mean age = 27.7, SD = 9.1). Results from multivariate regression analyses showed that there was a significant interaction effect between social support and acculturative stress (P = 0.025) on physical health, indicating that higher levels of social support buffered the negative effects of acculturative stress on physical health. Acculturative ...

SORL1 genetic variants and cerebrospinal fluid biomarkers of Alzheimer’s disease

European Archives of Psychiatry and Clinical Neuroscience — Fri, 27 Jan 2012 17:55:12 +0100

Abstract The neuronal sortilin-related receptor with A-type repeats (SORL1, also called LR11 or sorLA) is involved in amyloidogenesis, and the SORL1 gene is a major risk factor for Alzheimer’s disease (AD). We investigated AD-related CSF biomarkers for associations with SORL1 genetic variants in 105 German patients with mild cognitive impairment (MCI) and AD. The homozygous CC-allele of single nucleotide polymorphism (SNP) 4 was associated with increased Tau concentrations in AD, and the minor alleles of SNP8, SNP9, and SNP10 and the haplotype CGT of these SNPs were associated with increased SORL1 concentrations in MCI. SNP22 and SNP23, and the haplotypes TCT of SNP19-21-23, and TTC of SNP22-23-24 were correlated with decreased Aβ42 levels in AD. These results strengthen...

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Post-treatment follow-up procedures in cervical cancer patients previously treated with radiotherapy

Archives of Gynecology and Obstetrics — Fri, 27 Jan 2012 17:54:59 +0100

Conclusions Chest X-ray and Pap smear can be routinely performed for the first 2 years after radiotherapy, but can be omitted or used sparingly thereafter. Content Type Journal ArticleCategory Gynecologic OncologyPages 1-7DOI 10.1007/s00404-012-2235-4Authors Seiji Mabuchi, Department of Obstetrics and Gynecology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanFumiaki Isohashi, Department of Radiation Oncology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanShintaro Maruoka, Department of Radiation Oncology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanTakeshi Hisamatsu, Department of Obstetrics and Gynecology, Osaka University Graduate ...

The novel expression of Oct3/4 and Bmi1 in the root development of mouse molars

Cell and Tissue Research — Fri, 27 Jan 2012 17:54:29 +0100

This study aimed to investigate the characteristics of the cells involved in the root elongation. Octamer-binding factor 3/4 (Oct3/4) is known as one of the key regulators in maintaining the pluripotency and self-renewal properties of embryonic stem cells. Bmi1, the polycomb-group transcriptional repressor, has emerged as a key regulator in several cellular processes including stem cell self-renewal and cancer cell proliferation. At the beginning of root formation, ameloblasts expressed Oct3/4 in the nucleus, except in the apex of the cervical loop, in which Bmi1and cyclinD were expressed. At PN6, the expression of Oct3/4 in the ameloblasts shifted from the nucleus to the cytoplasm, whereas ameloblastin-negative Hertwig’s epithelial root sheath (HERS) cells expressed Bmi1 and cycli...

Fine structural and immunohistochemical detection of collar enamel in the teeth of Polypterus senegalus, an actinopterygian fish

Cell and Tissue Research — Fri, 27 Jan 2012 17:54:28 +0100

Abstract This is the first detailed report about the collar enamel of the teeth of Polypterus senegalus. We have examined the fine structure of the collar enamel and enamel organ of Polypterus during amelogenesis by light and transmission electron microscopy. An immunohistochemical analysis with an antibody against bovine amelogenin, an antiserum against porcine amelogenin and region-specific antibodies or antiserum against the C-terminus, middle region and N-terminus of porcine amelogenin has also been performed to examine the collar enamel matrix present in these teeth. Their ameloblasts contain fully developed Golgi apparatus, rough endoplasmic reticulum and secretory granules. During collar enamel formation, an amorphous fine enamel matrix containing no collagen fibrils ...

Induction of the Swallowing Reflex by Electrical Stimulation of the Posterior Oropharyngeal Region in Awake Humans

Dysphagia — Fri, 27 Jan 2012 17:54:22 +0100

Abstract We designed an electrical stimulation system to safely and reliably evoke the swallowing reflex in awake humans, and then examined the neural control of reflex swallowing initiated by oropharyngeal stimulation. A custom-made electrode connected to a flexible stainless-steel coil spring tube was introduced into the pharyngeal region through the nasal cavity and placed against the posterior wall of the oropharynx. Surface electrodes placed over the suprahyoid muscles recorded the electromyogram during swallowing. Swallowing reflexes were induced several times by 30 s of repetitive electrical pulse stimulation (intensity: 0.2–1.2 mA, frequency: 10–70 Hz, pulse duration: 1.0 ms). The onset latency of the swallowing reflex was measured over the ...

Residency Training Oversight(s) in Surgery: The History and Legacy of the Accreditation Council for Graduate Medical Education Reforms

Surgical Clinics of North America — Fri, 27 Jan 2012 11:25:19 +0100

Despite a quarter century of discourse since a sentinel event in New York City raised the question of appropriate oversight for graduate medical education, many questions remain unanswered. Even with the Accreditation Council for Graduate Medical Education rules in place, some opportunity remains to examine handoff methodology, the relationship of duty hours to education, and the impact of fatigue on resident performance. Neurophysiologic adjuncts applied concomitantly to evaluation of didactic performance offer promise for data-driven definition of the optimal shift. Concurrently, the merits of specialty-specific oversight of graduate medical education remain under active consideration. (Source: Surgical Clinics of North America)

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Letter From the Editor: Multimodality Imaging of the Pregnant Patient

Seminars in Ultrasound CT and MRI — Fri, 27 Jan 2012 08:38:44 +0100

It is with particular pleasure that I introduce this issue of Seminars. The Guest Editors, Drs. Tara Catanzano and Stephen O'Connor, and many of the authors practice at a large hospital located just down the street from where I live. Baystate Medical Center is the western campus of Tufts University Medical Center. It is a 783-bed acute care medical center with a medical staff of 450 physicians and a graduate medical education program of 253 residents. The members of the Radiology Department have consistently contributed to their field with numerous articles and exhibits over the years. Max Cloud, a former Chancellor of the American College of Radiology, was a member of this department, as was the author of a textbook of neuroradiology, Robert Kirkwood; then there is my good friend, David M...

Autism Spectrum Disorders: Practical Overview for Pediatricians

Pediatric Clinics of North America — Fri, 27 Jan 2012 06:14:51 +0100

Autism spectrum disorders (ASD) have a history and it started with the Jewish physician Leo Kanner (1894–1981), born in a small village in Galicia, which at that time was part of Austria-Hungary. He studied medicine in Berlin and graduated in 1921, but emigrated to the United States in 1924 to take a position at the State Hospital in Yankton County, South Dakota. In 1930, he was selected to develop the first child psychiatry service at Johns Hopkins Hospital, Baltimore, Maryland, where he in 1933 became associate professor of psychiatry. He was in reality the first physician in the world identified as a child psychiatrist, the founder of the first academic child psychiatry department at Johns Hopkins University Hospital, and his first textbook “Child Psychiatry” from 1935 was the fir...

Emergency airway management: Training and experience of chief residents in otolaryngology and anesthesiology

Head and Neck — Fri, 27 Jan 2012 05:00:00 +0100

ConclusionOtolaryngology and anesthesiology emergency airway management experience/training is heterogeneous and nonstandardized. Many chief residents graduate with little exposure to airway emergencies, especially surgical airways. Resident confidence levels are high despite minimal experience. This high confidence‐low experience dichotomy may reflect novice overconfidence and suggests the need for improved training methods. © 2012 Wiley Periodicals, Inc. Head Neck, 2012 (Source: Head and Neck)

Mathematics

Guardian Unlimited Science — Fri, 27 Jan 2012 01:00:00 +0100

The study of quantities through analysis, deduction and calculation - including mathematics, operational research and statisticsWhat will I learn?Familiar with fractals? Study a degree in maths and you soon will be.Broadly speaking, maths degrees should give you the basic ideas of pure mathematics (linear algebra, geometry etc), applied mathematics (calculus, mathematical methods, modelling and numerical analysis), and statistics (including probability and operational research).Your first year will probably give you an overview of the subject, introducing you to all the main areas. This should build on what you studied at A-level and also introduce you to a few new things. The next two or three years will give you the chance to specialise a bit more, perhaps in cryptology, group theory, fl...

UC Davis students to staff Knight's Landing clinic

bizjournals.com Health Care:Pharmaceuticals headlines — Thu, 26 Jan 2012 21:27:52 +0100

UC Davis medical students will open a new health clinic Sunday in Knight’s Landing to provide free care to underserved residents in rural Yolo County. The clinic will be open every third Sunday of the month. It will be staffed by medical students and undergraduates, along with volunteer doctors, nurses and graduate students in public health. Knights Landing hasn’t had a local medical clinic since Davis-based CommuniCare Health Centers pulled out in 2008. The clinic was losing more than $10,00 a month at the time, because of a drop in use and high numbers of people without insurance... (Source: bizjournals.com Health Care:Pharmaceuticals headlines)

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ABC screening for gastric cancer is not applicable in a Japanese population with high prevalence of atrophic gastritis

Gastric Cancer — Thu, 26 Jan 2012 16:46:18 +0100

Abstract A combination of the detection of serum anti-Helicobacter pylori antibody and measurement of the level of serum pepsinogens (PG)s, known as the ABC method, has been used in screening for gastric cancer. The ABC method has been shown to be useful in urban and/or younger populations. The aim of this study was to assess whether this method is applicable for an agricultural population with a high incidence of gastric cancer. In all, 1048 healthy adults (401 men and 647 women) who participated in a mass survey in April 2005 were examined. Their serum samples were tested to determine the prevalence of anti-H. pylori antibody, and the levels of PG I and PG II were also measured to assess the presence of atrophic gastritis. Of the elderly subjects born before 1940, 59.4% w...

Magnolol Protects Osteoblastic MC3T3-E1 Cells Against Antimycin A-Induced Cytotoxicity Through Activation of Mitochondrial Function

Inflammation — Thu, 26 Jan 2012 16:44:49 +0100

Abstract Antimycin A treatment of cells blocks the mitochondrial electron transport chain and leads to elevated ROS generation. In the present study, we investigated the protective effects of magnolol, a hydroxylated biphenyl compound isolated from Magnolia officinalis, on antimycin A-induced toxicity in osteoblastic MC3T3-E1 cells. Osteoblastic MC3T3-E1 cells were pre-incubated with magnolol before treatment with antimycin A. Cell viability and mineralization of osteoblasts were assessed by MTT assay and Alizarin Red staining, respectively. Mitochondrial dysfunction in cells was measured by mitochondrial membrane potential (MMP), complex IV activity, and ATP level. The cellular antioxidant effect of magnolol in osteoblastic MC3T3-E1 cells was assessed by measuring cardioli...

A radio transmission pH measurement system for continuous evaluation of fluid pH in the rumen of cows

Veterinary Research Communications — Thu, 26 Jan 2012 16:44:10 +0100

Abstract We developed a novel wireless radio transmission pH measurement system to continuously monitor ruminal bottom pH in cows, and compared these measurements to pH values determined by a spot-sample method. The wireless system consists of a pH sensor, data measurement receiver, relay unit, and personal computer with special software. The bullet-shaped sensor can be easily administered orally via a catheter into the rumen, without surgery. The glass electrode, using a temperature compensation system, can detect the rumen fluid pH with high accuracy. The ruminal bottom pH in healthy rumen-fistulated cows was measured as 6.52 ± 0.18 by the wireless system and as 6.62 ± 0.20 by the spot-sample method; with a correlation between pH measurements using these differ...

Multiple sleep bruxism data collected using a self-contained EMG detector/analyzer system in asymptomatic healthy subjects

Sleep and Breathing — Thu, 26 Jan 2012 06:56:45 +0100

Conclusion Substantial night-to-night variability in masseter EMG activity levels was clearly observed in our subjects. There was no evidence of a suppressed or elevated first-night effect-like variability on masseter muscle EMG level seen in these subjects using a small portable self-contained EMG detector/analyzer. These data suggest that recordings should be at least 5–6-nights duration to establish a reasonable measure of an individual's average nightly masseter EMG level. Content Type Journal ArticleCategory Original ArticlePages 1-4DOI 10.1007/s11325-011-0602-1Authors Hajime Minakuchi, Department of Oral Rehabilitation and Regenerative Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-wa...

Microbiological characteristics of clinical isolates of Cryptococcus spp. in Bahia, Brazil: molecular types and antifungal susceptibilities

European Journal of Clinical Microbiology and Infectious Diseases — Thu, 26 Jan 2012 06:56:41 +0100

This study is the first to describe the susceptibility profiles of molecular and clinical isolates of Cryptococcus in Bahia, Brazil. The high percentage of C. gattii isolates belonging to the VGII genotype and its lower susceptibility to antifungal agents highlight the importance of knowing which species are involved in cryptococcal infections in northeastern Brazil. Content Type Journal ArticleCategory ArticlePages 1-6DOI 10.1007/s10096-011-1488-3Authors C. S. Matos, Graduate Program in Pharmacy, Faculty of Pharmacy, UFBA, Salvador, BrazilA. de Souza Andrade, Program for Scientific Initiation, Faculty of Pharmacy, UFBA, Salvador, BrazilN. S. Oliveira, Couto Maia Specialized Hospital, Salvador, BrazilT. F. Barros, Department of Clinical and Toxicological Analysis, Faculty of Pharm...

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Prognostic effects of oral anti-cancer drugs as adjuvant chemotherapy for 2 years after gastric cancer surgery

Surgery Today — Thu, 26 Jan 2012 06:44:05 +0100

Conclusions The 2-year administration of oral anti-cancer drugs as postoperative adjuvant chemotherapy might improve the outcome of stage II, III gastric cancer patients. Randomized control trials are warranted to prove the effectiveness of this 2-year regimen. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00595-012-0129-5Authors Toshiro Okuyama, Department of Surgery, Fukuoka City Hospital, 13-1 Yoshizuka-honmachi, Hakata-ku, Fukuoka, 812-0046 JapanDaisuke Korenaga, Department of Surgery, Fukuoka City Hospital, 13-1 Yoshizuka-honmachi, Hakata-ku, Fukuoka, 812-0046 JapanAi Edagawa, Department of Surgery, Fukuoka City Hospital, 13-1 Yoshizuka-honmachi, Hakata-ku, Fukuoka, 812-0046 JapanShinji Itoh, Department of Surgery, Fukuoka City Hospi...

Cavefish: A Study in Evo-Devo (interview)

ActionBioscience — Thu, 26 Jan 2012 05:00:00 +0100

Why are cavefish a good example of evo-devo? The blind Mexican cavefish is one of the few species that has an ancestor on the surface and a descendent in caves. Jeffery: Scientists study all kinds of organisms in evolutionary developmental biology, but when I started working in the evo-devo field, I decided that in order to understand how development evolved, we would have to look at two closely related species that have diverged recently [developed in separate directions] or to look at the same species in the process of divergence. I looked around for models, and I found several of them. One of them happened to be in caves, and the species is called Astyanax mexicanus, the blind Mexican cavefish. This cave organism is one of the few in which the acknowledged ancestor is still present on...

Synthesis, Characterization and X-Ray Structure of Bis(O-propyldithiocarbonato-κ2S,S′)bis(4-cyanopyridine-κN)nickel(II)

Journal of Chemical Crystallography — Wed, 25 Jan 2012 18:14:55 +0100

Abstract The [Ni(S2COCH2CH2CH3)2(C6H4N2)2] adduct of 4-cyanopyridine with [Ni(S2COCH2CH2CH3)2] was synthesized and characterized by elemental analysis, magnetic susceptibility measurement, IR, electronic spectral data, Thermogravimetric analysis/DTA techniques and X-ray diffraction analysis. The Ni atom in the title complex is octahedrally coordinated within a trans-N2S4 donor set, with the Ni atom located on a centre of inversion. The title complex crystallizes in the monoclinic space group P2 1 /c with unit cell parameters a = 11.75(4), b = 11.62(3), c = 9.20(2) Å, β = 104.99(3)°. Crystal structure was solved by direct methods and refined by full matrix least squares procedures to a final R-value of 0.0294 for 1895 observ...

A randomized phase-II trial comparing sequential and concurrent paclitaxel with oral or parenteral fluorinated pyrimidines for advanced or metastatic gastric cancer

Gastric Cancer — Wed, 25 Jan 2012 18:12:35 +0100

Conclusion Our study did not show sufficient prolongation of survival with the concurrent strategy to proceed to a phase-III trial; however, the sequential arms showed survival comparable to that in the concurrent arms, with less toxicity. In patients who are ineligible for cisplatin (CDDP), sequential treatment starting with S-1 and proceeding to PTX would be a good alternative strategy, considering quality of life (QOL) and the cost-benefits of an oral agent as first-line treatment. Content Type Journal ArticleCategory Original articlePages 1-7DOI 10.1007/s10120-011-0124-3Authors Kazuhiro Nishikawa, Department of Surgery, Osaka General Medical Center, 3-1-56 Bandai-higashi, Sumiyoshi-ku, Osaka, 558-8558 JapanSatoshi Morita, Department of Biostatistics and Epidemi...

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Relationship between decreased swimming velocity and muscle activity during 200-m front crawl

European Journal of Applied Physiology — Wed, 25 Jan 2012 18:12:24 +0100

Abstract The aims of this study were (1) to evaluate changes in muscle activity associated with physiological fatigue and decreased swimming velocity (SV) during 200 m of front crawl swimming, and (2) to examine the relationship between the decreased SV and changes in kinematic or electromyogram parameters. Twenty swimmers participated in a 4 × 50-m swim test. The surface EMG of 11 muscles (7 in the upper limbs and 4 in the lower limbs) was measured and the mean amplitude value (MAV) for one stroke cycle was obtained. The SV and arm angular velocity (AAV) of shoulder flexion during the first (early stroke) and second (late stroke) half of the underwater arm stroke were analyzed using an underwater camera. The AAV, the MAV of flexor carpi ulnaris (FCU), bice...

Pre-internship Nigerian medical graduates lack basic musculoskeletal competency

International Orthopaedics — Wed, 25 Jan 2012 18:11:34 +0100

Conclusion Basic musculoskeletal competency among pre-internship Nigerian medical-school graduates is inadequate. Content Type Journal ArticleCategory Original PaperPages 1-4DOI 10.1007/s00264-012-1485-xAuthors Timothy Eyo Nottidge, Department of Orthopaedics and Traumatology, Faculty of Clinical Sciences, University of Uyo, Uyo, Akwa-Ibom State, NigeriaUdeme Ekrikpo, Department of Internal Medicine, University of Uyo Teaching Hospital, Uyo, NigeriaAdeleke Olusegun Ifesanya, Department of Surgery, University of Ibadan, Ibadan, NigeriaRichard E. Nnabuko, National Orthopaedic Hospital, Enugu, Enugu, NigeriaEdwin Maduakonam Dim, Department of Orthopaedics and Traumatology, Faculty of Clinical Sciences, University of Uyo, Uyo, Akwa-Ibom State, NigeriaClement Inyang Udoinyan...

Metabolic syndrome and insulin resistance in migraine

The Journal of Headache and Pain — Wed, 25 Jan 2012 18:07:54 +0100

This study was therefore undertaken to compare the clinical characteristics of migraine in patients with and without metabolic syndrome and insulin resistance. 135 consecutive patients with migraine diagnosed on the basis of International Headache Society criteria were subjected to clinical evaluation as per fixed protocol. Headache severity, frequency and functional disability were recorded. Metabolic syndrome was diagnosed as per National Cholesterol Education Programme: Adult Treatment Panel III and International Diabetic Federation criteria. Insulin resistance was calculated by homeostases model assessment. Their age ranged between 14 and 61 years and 108 were females. Metabolic syndrome was present in 31.9% patients and only 13 were obese. Insulin resistance was present in ...

Post-transplantation lymphoproliferative disorder in living-donor liver transplantation: a single-center experience

Surgery Today — Wed, 25 Jan 2012 18:04:12 +0100

Conclusion Although PTLD is potentially life-threatening, it can be managed by appropriate and prompt treatment, with a good outcome. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00595-012-0127-7Authors Chikashi Nakanishi, Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryou-machi, Aobaku, Sendai, 980-8574 JapanNaoki Kawagishi, Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryou-machi, Aobaku, Sendai, 980-8574 JapanSatoshi Sekiguchi, Division of Advanced Surgical Science and Technology, Graduate School of Medicine, Tohoku University, 1-1 Seiryou-machi, Aobaku, Sendai, 980-8574 JapanYorihiro Akamatsu, Division of Advanc...

Contest aims to inspire students to create healthcare apps

Healthcare IT News — Wed, 25 Jan 2012 14:59:40 +0100

The Institute of Medicine and National Academy of Engineering has launched a contest to spur undergraduate and graduate students to create health-related apps. The prize for the winning team: $10,000. Students pursuing degrees toward careers in health, engineering and computer science could earn a distinctive addition to their resumes by participating in the "Go Viral to Improve Health" contest, officials say. read more (Source: Healthcare IT News)

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How to Make Science and Tech Jobs More Enticing to Undergrads

Scientific American - Official RSS Feed — Wed, 25 Jan 2012 12:59:00 +0100

The number of U.S. undergraduate degrees being awarded in most STEM disciplines (science, technology, engineering and math) has risen steadily in recent years{link to G Sci page}. Yet some American employers say they are having trouble finding candidates to fill STEM jobs. The mismatch is not occurring because of an actual shortage of graduates; the numbers of job openings and new degree holders align fairly closely. And the shortfall is not because more foreign-born students are returning home after earning U.S. degrees, as has been rumored lately. [More] (Source: Scientific American - Official RSS Feed)

Study Finds Religion Helps Us Gain Self-Control

Health News from Medical News Today — Wed, 25 Jan 2012 10:00:00 +0100

Thinking about religion gives people more self-control on later, unrelated tasks; according to results from a series of recent Queen's University study. "After unscrambling sentences containing religiously oriented words, participants in our studies exercised significantly more self-control," says psychology graduate student and lead researcher on the study, Kevin Rounding. Study participants were given a sentence containing five words to unscramble. Some contained religious themes and others did not... (Source: Health News from Medical News Today)

The transformation of phytolith morphology as the result of their exposure to high temperature

Microscopy Research and Technique — Wed, 25 Jan 2012 05:00:00 +0100

AbstractPhytoliths are an important component for interpreting the ancient botanical record. However, phytoliths can be altered through heating, either as the result of such activities as firing ceramics, clay molds use for casting metal or in hearths. Phytoliths can also be altered through heating as the result of creating comparative sample from living plants. By heating phytoliths at graduated intervals it was found that different types of phytoliths lost their diagnostic morphological characteristics at significantly different temperatures. The phytoliths used in this study are derived from economically important plants to Chinese archaeology and culture. Given the consistent results of the alteration of different type of phytoliths at specific temperatures it should eventually be poss...

Management of postoperative atrial fibrillation

Journal of Anesthesia — Tue, 24 Jan 2012 18:14:08 +0100

Abstract The impact of postoperative atrial fibrillation (PAF) on patient outcomes has prompted intense investigation into the optimal methods for prevention and treatment of this complication. In the prevention of PAF, β-blockers and amiodarone are particularly effective and are recommended by guidelines. However, their use requires caution due to the possibility of drug-related adverse effects. Aside from these risks, perioperative prophylactic treatment with statins seems to be effective for preventing PAF and is associated with a low incidence of adverse effects. PAF can be treated by rhythm control, heart-rate control, and antithrombotic therapy. For the purpose of heart rate control, β-blockers, calcium-channel antagonists, and amiodarone are used. In patients with...

Computational measurement of joint space width and structural parameters in normal hips

Archives of Orthopaedic and Trauma Surgery — Tue, 24 Jan 2012 18:09:26 +0100

Conclusions There were interindividual variations of JSW in normal population, depending on sites of the weight-bearing area, side, gender, age, and hip structural parameters. For accurate diagnosis and assessment of hip osteoarthritis, consideration of those influential factors other than degenerative change is important. Content Type Journal ArticleCategory Orthopaedic SurgeryPages 1-8DOI 10.1007/s00402-012-1463-1Authors Takashi Nishii, Department of Orthopaedic Medical Engineering, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, JapanToshiyuki Shiomi, Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, JapanTakashi Sakai, Department of Orthopaedic Surgery, Osaka University Graduate Sch...

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Thousands of Industrial Systems Unwittingly Hooked Up to Internet

Scientific American - Official RSS Feed — Tue, 24 Jan 2012 16:45:00 +0100

The computers that control large industrial control systems the sewage plants, power stations, and assembly lines that keep civilization running aren’t supposed to be online. Computers online tend to get hacked, of course, and you wouldn’t want your local power plant under rogue control . But a graduate student was able to locate and map more than 10,000 industrial control systems that are directly connected to the Internet, as reported by Kim Zetter at Wired’s Threat Level Blog . What’s more, only 17 percent of those devices bothered to ask for authorization to connect, suggesting that network managers simply didn’t realize that their control systems were online.The finding adds a discouraging twist to worries that hackers might take over critical infrastruct...

Sacred Heart University to offer master's in health IT

CMIO.net: The News Weekly for Health IT Executives — Tue, 24 Jan 2012 15:53:45 +0100

Sacred Heart University in Fairfield, Conn., is adding a graduate-level health IT program to its course catalog for the 2012 to 2013 academic year. (Source: CMIO.net: The News Weekly for Health IT Executives)

DNA methylation status of REIC/Dkk-3 gene in human malignancies

Journal of Cancer Research and Clinical Oncology — Tue, 24 Jan 2012 12:27:14 +0100

Conclusions REIC/Dkk-3 type-a methylation was frequently detected in a broad range of cancers and appeared to play a key role in silencing REIC/Dkk-3 type-a expression in these malignancies. Content Type Journal ArticleCategory Original PaperPages 1-11DOI 10.1007/s00432-012-1158-6Authors Tatsuro Hayashi, Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Okayama, 700-8558 JapanHiroaki Asano, Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, 2-5-1 Shikata-cho, Okayama, 700-8558 JapanShinichi Toyooka, Department of Cancer and Thoracic Surgery, Graduate School of Medicine, Dentistry and Pharm...

Morbidity and Mortality Results From a Prospective Randomized Controlled Trial Comparing Billroth I and Roux-en-Y Reconstructive Procedures After Distal Gastrectomy for Gastric Cancer

World Journal of Surgery — Tue, 24 Jan 2012 07:55:29 +0100

Conclusions We concluded that B-I reconstruction was superior to R-Y reconstruction in terms of perioperative complications. Content Type Journal ArticlePages 1-6DOI 10.1007/s00268-011-1408-9Authors Hiroshi Imamura, Department of Surgery, Sakai Municipal Hospital, Osaka, JapanShuji Takiguchi, Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 JapanKazuyoshi Yamamoto, Department of Gastroenterological Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871 JapanMotohiro Hirao, Department of Surgery, Osaka National Hospital, Osaka, JapanJunya Fujita, Department of Surgery, Toyonaka Municipal Hospital, Toyonaka, JapanIsao Miyashiro, Department of Surgery, Osaka ...

Invasion of the Hepatic Artery is a Crucial Predictor of Poor Outcomes in Gallbladder Carcinoma

World Journal of Surgery — Tue, 24 Jan 2012 07:55:18 +0100

Conclusions Invasion of the HA is a crucial prognostic factor in patients with gallbladder carcinoma. Content Type Journal ArticlePages 1-6DOI 10.1007/s00268-011-1413-zAuthors Akihiko Kobayashi, Departments of Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, 305-8575 JapanTatsuya Oda, Departments of Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, 305-8575 JapanKiyoshi Fukunaga, Departments of Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, 305-8575 JapanRyoko Sasaki, Departments of Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, 305-8575 JapanNobuhiro Ohkohchi, Departments of Surgery, Graduate School of Co...

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A Comparison of Logistic Regression Analysis and an Artificial Neural Network Using the BI-RADS Lexicon for Ultrasonography in Conjunction with Introbserver Variability

Journal of Digital Imaging — Tue, 24 Jan 2012 07:54:54 +0100

Abstract To determine which Breast Imaging Reporting and Data System (BI-RADS) descriptors for ultrasound are predictors for breast cancer using logistic regression (LR) analysis in conjunction with interobserver variability between breast radiologists, and to compare the performance of artificial neural network (ANN) and LR models in differentiation of benign and malignant breast masses. Five breast radiologists retrospectively reviewed 140 breast masses and described each lesion using BI-RADS lexicon and categorized final assessments. Interobserver agreements between the observers were measured by kappa statistics. The radiologists’ responses for BI-RADS were pooled. The data were divided randomly into train (n = 70) and test sets (n = 70). Using train set, opti...

Skeletal Analysis of the Long Bone Abnormality (lbab/lbab) Mouse, A Novel Chondrodysplastic C-Type Natriuretic Peptide Mutant

Calcified Tissue International — Tue, 24 Jan 2012 07:53:59 +0100

In this study, we analyzed the chondrodysplastic skeletal phenotype of lbab/lbab mice. At birth, lbab/lbab mice are only slightly shorter than their wild-type littermates. Nevertheless, lbab/lbab mice do not undergo a growth spurt, and their final body and bone lengths are only ~60% of those of wild-type mice. Histological analysis revealed that the growth plate in lbab/lbab mice, especially the hypertrophic chondrocyte layer, was significantly thinner than in wild-type mice. Overexpression of CNP in the cartilage of lbab/lbab mice restored their thinned growth plate, followed by the complete rescue of their impaired endochondral bone growth. Furthermore, the bone volume in lbab/lbab mouse was severely decreased and was recovered by CNP overexpression. On the other hand, the thickness ...

Vincristine exacerbates asymptomatic Charcot–Marie–Tooth disease with a novel EGR2 mutation

Neurogenetics — Tue, 24 Jan 2012 07:36:18 +0100

Abstract Neurotoxicity is a common side effect of vincristine (VCR) treatment. Severe exacerbations of neuropathy have been reported in patients with Charcot–Marie–Tooth disease (CMT) 1A with duplication of the peripheral myelin protein 22 (PMP22) gene. However, whether or not VCR exacerbates neuropathies through mutations in other CMT-associated genes besides PMP22 duplication has not been well studied. The purpose of this study was to identify mutations in any CMT-associated genes in a patient with hypersensitivity to VCR. We performed clinical, electrophysiological, and genetic examinations of a 23-year-old woman, who was hypersensitive to low-dose VCR, and her healthy mother. DNA analysis was performed using our specially designed resequencing array that simultaneous...

State-dependent precursors of seizures in correlation-based functional networks of electrocorticograms of patients with temporal lobe epilepsy

Neurological Sciences — Tue, 24 Jan 2012 07:34:36 +0100

Abstract Accurate prediction of epileptic seizures will open novel therapeutic possibilities for patients with intractable epilepsy. We attempted to identify precursors of seizures in the functional networks of electrocorticograms by applying graph theory. Long-term electrocorticograms for periods of 39–76 h from three patients with temporal lobe epilepsy were investigated using pair-wise cross-correlations. Time-varying network properties suggested that there were several distinct brain states. Although functional networks during seizures could be characterized as having a regular topography, no consistent characteristics of functional networks were found immediately prior to seizure onsets. However, it was found that seizures under an identical state were followed...

Preferred place of care and place of death of the general public and cancer patients in Japan

Supportive Care in Cancer — Tue, 24 Jan 2012 07:34:11 +0100

In conclusion, establishing more accessible home and hospice service is strongly required through arranging regional resources to reduce family burden, alleviating patient-perceived burdens, and improving 24-h support at home. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00520-011-1373-8Authors Akemi Yamagishi, Department of Nursing, Seirei Christopher University, 3453 Mikatahara, Kita-ku, Hamamatsu, Shizuoka 433-8558, JapanTatsuya Morita, Department of Palliative and Supportive Care, Palliative Care Team, and Seirei Hospice, Seirei Mikatahara General Hospital, Hamamatsu, JapanMitsunori Miyashita, Department of Palliative Nursing, Health Sciences, Tohoku University Graduate School of Medicine, Sendai, JapanSaran Yoshida, Department of Clinical Psycholo...

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Diet and exercise training reduce blood pressure and improve autonomic modulation in women with prehypertension

European Journal of Applied Physiology — Tue, 24 Jan 2012 07:33:12 +0100

Performance of the Japanese GFR equation in potential kidney donors

Clinical and Experimental Nephrology — Tue, 24 Jan 2012 07:30:47 +0100

Conclusion The Japanese GFR equation underestimated GFR in potential kidney donors. Higher creatinine generation compared with CKD subjects may contribute to the underestimation of GFR by the Japanese GFR equation in potential kidney donors. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s10157-012-0586-6Authors Masaru Horio, Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, Suita, Osaka 565-0871, JapanYoshinari Yasuda, Department of Nephrology, Nagoya University Graduate School of Medicine, Nagoya, JapanJyunya Kaimori, Departments of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Osaka, JapanNaotsugu Ichimaru, Department of Specific Organ Regulation, Osaka Universit...

Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expressions in gallbladder carcinoma

Surgery Today — Tue, 24 Jan 2012 07:29:05 +0100

Conclusion Low TS mRNA was correlated with a high incidence of lymph node metastasis and advanced clinical stage. Therefore, TS gene expression may help identify patients at increased risk of the progression of GBC. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00595-012-0118-8Authors Shuichi Iwahashi, Department of Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503 JapanMitsuo Shimada, Department of Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima, 770-8503 JapanTohru Utsunomiya, Department of Surgery, Institute of Health Biosciences, The University of Tokushima Graduate School, 3-18-15 Kuram...

Plasma RANTES and eotaxin levels are correlated with the severity of chronic rhinosinusitis

European Archives of Oto-Rhino-Laryngology — Tue, 24 Jan 2012 07:28:21 +0100

Abstract Eosinophilia occurs in up to 75–90% of nasal polyps in Caucasians. The chemokines eotaxin and RANTES increase eosinophil recruitment, activation, and survival, and these chemokines are significantly expressed in nasal polyps. We hypothesized that eotaxin and RANTES plasma levels might be correlated with disease severity. We compared the eotaxin and RANTES plasma levels in 20 Taiwanese patients with chronic rhinosinusitis and nasal polyps and 20 Taiwanese healthy controls. Eotaxin and RANTES plasma levels were measured by ELISA and disease severity was scored by CT scans. Compared to controls, patients with nasal polyps had significantly elevated plasma levels of eotaxin and RANTES and increased peripheral blood eosinophils (p < 0.001). Eotaxin plasma...

Repair of critical long bone defects using frozen bone allografts coated with an rhBMP-2-retaining paste

Journal of Orthopaedic Science — Tue, 24 Jan 2012 07:21:07 +0100

Conclusions This experimental study suggest that allogeneic bone grafting in combination with rhBMP-2 and its local delivery system may represent an innovative approach to the reconstruction of bone defects. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00776-012-0196-xAuthors Hiroyuki Yasuda, Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-Machi, Abeno-Ku, Osaka, 545-8585 JapanKoichi Yano, Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-Machi, Abeno-Ku, Osaka, 545-8585 JapanShigeyuki Wakitani, Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-Machi, Abeno-Ku, Osaka, 545-8585 JapanTomiya Matsumot...

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A case of adult-onset Still’s disease (AOSD)-like manifestations abruptly developing during confirmation of a diagnosis of metastatic papillary thyroid carcinoma

Modern Rheumatology — Tue, 24 Jan 2012 06:51:41 +0100

Abstract A 68-year-old Japanese man was admitted to our hospital suffering from abrupt onset of high fever accompanied by arthralgia, myalgia, sore throat, macular eruption, and liver dysfunction. Six months before the onset of these manifestations, 18F-fluoro-deoxy-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) had detected, unexpectedly, three calcified thyroid lesions without 18F-FDG uptake. Two months before the onset of the present manifestations, ultrasonography-guided fine-needle aspiration had led to a diagnosis of papillary thyroid carcinoma (PTC). Soon after the occurrence of the rheumatic manifestations, a subsequent 18F-FDG PET/CT scan showed not only the three thyroid lesions, the same as those in the previous scan, but also 18F-FDG upt...

Discontinuation of adalimumab treatment in rheumatoid arthritis patients after achieving low disease activity

Modern Rheumatology — Tue, 24 Jan 2012 06:51:41 +0100

Conclusion Some RA patients who have achieved LDA with ADA monotherapy can discontinue the biologic without incurring increased disease activity. A prospective randomized study is required to confirm the results of our study. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s10165-011-0586-5Authors Masayoshi Harigai, Department of Pharmacovigilance, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8519 JapanTsutomu Takeuchi, Division of Rheumatology and Clinical Immunology, Department of Internal Medicine, Faculty of Medicine, Keio University, Tokyo, JapanYoshiya Tanaka, The First Department of Internal Medicine, University of Occupational and Environmental Health, Kita...

NEFA/nucleobindin-2 is a target autoantigen of the anti-Wa antibody and is associated with transfer RNA

Modern Rheumatology — Tue, 24 Jan 2012 06:51:40 +0100

Conclusions We have demonstrated that the Wa antigen is NEFA or nucleobindin-2, which binds specific tRNA species, and is distributed in specific human tissues. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s10165-011-0582-9Authors Yoshitaka Imura, Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, 54 Shogoin-kawahara-cho, Sakyo-ku, Kyoto, 606-8507 JapanYuichiro Shirai, Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Shinjuku-ku, Tokyo, 160-8582 JapanTakaki Nojima, Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, 54 Shogoin-kawahara-cho, Sakyo-ku, Kyoto, 606-8507 JapanRan Nakashima, Department of...

Anatomical survey of terminal branching patterns of superficial branch of radial nerve in fetuses

Surgical and Radiologic Anatomy — Tue, 24 Jan 2012 06:46:18 +0100

Conclusions Detailed knowledge of the distribution patterns of terminal branches of superficial branch of radial nerve in hand will enhance the success rate of regional blocks or hand surgeries and minimize the postoperative complications due to injury to nerve or vascular structures. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00276-012-0932-0Authors Richa Gupta, Department of Anatomy, Post Graduate Institute of Medical Education and Research (PGIMER), # 123-C Type, Sector 24-A, Chandigarh, 160023 IndiaAnjali Aggarwal, Department of Anatomy, Post Graduate Institute of Medical Education and Research (PGIMER), # 123-C Type, Sector 24-A, Chandigarh, 160023 IndiaDaisy Sahni, Department of Anatomy, Post Graduate Institute of Medical Educat...

Impact of a Six-Year Integrated Thoracic Surgery Training Program at the Medical College of Wisconsin [ORIGINAL ARTICLES: ADULT CARDIAC]

The Annals of Thoracic Surgery — Tue, 24 Jan 2012 05:00:00 +0100

Conclusions Institution of a 6-year integrated thoracic surgery training program at the Medical College of Wisconsin led to a significant increase in number of applications. Additionally, the 6-year applicants appeared to be more academically accomplished than previous applicants to the traditional 2-year program. While early in the experience, it appears that interest in thoracic surgery is high among medical students and institution of a 6-year program has the potential to once again attract the "best and the brightest" to this specialty. (Source: The Annals of Thoracic Surgery)

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Why UK-trained doctors leave the UK: cross-sectional survey of doctors in New Zealand

JRSM — Tue, 24 Jan 2012 05:00:00 +0100

Conclusions Emigrant doctors in New Zealand had higher job satisfaction than their UK-based contemporaries, and few wanted to return. The predominant reason for staying in New Zealand was a preference for the lifestyle there. (Source: JRSM)

My College Friend Suddenly Cut Off Our Friendship

Psychology Today Relationships Center — Tue, 24 Jan 2012 01:07:16 +0100

While I was in college I decided to room with one of my really good friends that I had made at school. Things seemed to go great that year and I felt that we had become really close. However, near the end of that school year she suddenly left for home and refused to take my calls. read more (Source: Psychology Today Relationships Center)

How to learn to love maths

Guardian Unlimited Science — Mon, 23 Jan 2012 20:00:00 +0100

New advice suggests children should study maths until they leave school. Don't be scared though, numbers are wonderful, fascinating thingsBritain is about to fall in love with maths. Well, that's the dream. Yesterday one of the government's top advisers on further education said that maths should be compulsory for all students until 18 or 19 – no matter what else they are studying. Professor Steve Sparks, chairman of the Advisory Committee on Mathematics Education, also said that he wants a new maths qualification between GCSE and AS-level to be introduced by 2016.Maths is justified in this country because it is useful. Sparks said his proposals were necessary because young people need a better grasp of maths to compete in the job market, where an understanding of technology and numeracy...

Foulkes Foundation Fellowships

Society for Endocrinology — Mon, 23 Jan 2012 12:00:00 +0100

The Foulkes Foundation is a charitable foundation that was established in 1972. The fellowships were first awarded in 1975 and their purpose is to promote medical research, the training of scientists and the study of medicine. The fellowship scheme provides financial support for recently qualified PhD science graduates with research experience who want additionally to take a medical degree or medical graduates wanting to take a life science PhD Degree. In both cases the graduate must intend to do medical research after qualification, and science graduates must continue part-time research during their medical training with an appropriate named supervisor. Click on the link below for more information. The deadline for applications is 15 March 2012. Foulkes Foundation (Source: Society for ...

Boosting Immunity Where It Counts, Not Just Near Vaccine Site

Health News from Medical News Today — Mon, 23 Jan 2012 09:00:00 +0100

Researchers at Duke University Medical Center have created synthetic nanoparticles that target lymph nodes and greatly boost vaccine responses, said lead author Ashley St. John, Ph.D., a researcher at Duke-NUS Graduate Medical School. The paper was published online in the journal Nature Materials on Jan. 22. Currently all other adjuvants (substances added to vaccines to help to boost the immune response) are thought to enhance immunity at the skin site where the vaccine is injected rather than going to the lymph nodes, where the most effective immune reactions occur... (Source: Health News from Medical News Today)

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A longitudinal integrated placement and medical students' intentions to practise rurally.

Rural Remote Health — Mon, 23 Jan 2012 07:37:27 +0100

Conclusions The richness of the informal curriculum in a longitudinal rural placement powerfully influenced students' intentions to practise rurally. It provided an important context for learning and evolving notions of professionalism and rural professional identity. This richness could be reinforced by developing formal curricula using educational activities based around service-led and interprofessional learning. To overcome the contextual barriers, the rural workforce development model needs to focus on socialising medical students into rural and remote medicine. More generic issues include student selection, further expansion of structured vocational training pathways that vertically integrate with longitudinal rural placements and the maintenance of rurally focused support through...

Why does a rural background make medical students more likely to intend to work in rural areas and how consistent is the effect? A study of the rural background effect.

The Australian Journal of Rural Health — Mon, 23 Jan 2012 02:01:27 +0100

Conclusion: Why the RBE occurs remains unexplained. Evidence was found of a reduced RBE under certain climatic conditions and personal circumstances, but further work is required to better understand why rural background is so strongly related with rural medical intention and practice. PMID: 22250874 [PubMed - in process] (Source: The Australian Journal of Rural Health)

Nonprogression through graduated driver licensing: characteristics, traffic offending, and reasons for nonprogression. - Langley J, Begg D, Brookland R, Samaranayaka A, Jordan H, Davie G.

SafetyLit: All (Unduplicated) — Sat, 21 Jan 2012 12:05:52 +0100

Objectives: In a graduated driver license environment, (1) compare nonprogressors with progressors in terms of prelearner license sociodemographic and behavioral factors, (2) determine whether nonprogressors were more likely to have had a traffic offense t... (Source: SafetyLit: All (Unduplicated))

Positive Effect of Lower Body Compression Garments on Subsequent 40-kM Cycling Time Trial Performance

Journal of Strength and Conditioning Research — Sat, 21 Jan 2012 10:29:34 +0100

This study aimed to investigate the effect of wearing graduated compression garments during recovery on subsequent 40-km time trial performance. In a randomized single-blind crossover experiment, 14 trained multisport male athletes (mean ± SD: age 33.8 ± 6.8 years, 40-km time 66:11 ± 2:10 minutes:seconds) were given a graduated full-leg-length compressive garment (76% Meryl Elastane, 24% Lycra) or a similar-looking noncompressive placebo garment (92% Polyester, 8% Spandex) to wear continuously for 24 hours after performing an initial 40-km time trial in their normal cycling attire. After the 24-hour recovery period, the compression (or placebo) garments were removed, and a second 40-km time trial was then completed to gauge the effect of each garment on subsequent performance. One week ...

Some useful insights for graduate students beginning their research in physiological psychology: Anecdotes and attitudes.

Behavioural Brain Research — Sat, 21 Jan 2012 05:00:00 +0100

Authors: Teitelbaum P Abstract This paper is based on my experiences in 40 years of research in behavioral neuroscience. It is aimed at giving help to beginning graduate students with advice for how to do their research. PMID: 22285421 [PubMed - as supplied by publisher] (Source: Behavioural Brain Research)

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Colorectal cancer screening practise is influenced by ethnicity of medical practitioner and patient

Journal of Gastroenterology and Hepatology — Fri, 20 Jan 2012 20:47:39 +0100

Conclusions: Considerable differences existed in GPs' CRC screening practises. Indications for use of FOBT and the subsequent investigation of a positive FOBT also varied according to GPs' ethnicity, independent of medical training. Patient's ethnicity and associated language and cultural barriers may affect screening uptake, which may negatively affect the health of immigrants. Resources and culture‐specific interventions are recommended to improve overall screening participation. (Source: Journal of Gastroenterology and Hepatology)

Let's Not Skew Ourselves

Journal of Oral and Maxillofacial Surgery — Fri, 20 Jan 2012 20:18:48 +0100

This above all: to thine own self be true, And it must follow, as the night the day, Thou canst not then be false to any man. —William Shakespeare, Hamlet One of my more humbling academic experiences was a required class in economics during graduate school. I confess having little success thinking like an economist, a point perhaps explaining the draw of an academic career. Over the years, however, I have found that the broad strokes of economic concepts—despite my ignorance—often resonate with my circumstances. (Source: Journal of Oral and Maxillofacial Surgery)

Triage Consulting Group: 2012 Career Opportunities

Support for International Change : HIV AIDS — Fri, 20 Jan 2012 16:26:41 +0100

Triage Consulting Group, a San Francisco based financial consulting firm, seeks bright, motivated individuals with a hunger to learn and a willingness to contribute to fill summer internships as well as a full time Associate position! Career potential at Triage is unlimited as we place strong emphasis on promotion from within. Numerous Associates (including notable SIC Alumni) have enjoyed this rewarding career path. So can you. Click the picture for more information! For Juniors entering Senior year: Apply for the 2012 Summer Internship Position For Graduating Seniors: Apply for the full-time Associate position Find out if your school is having an on campus Triage info session by clicking here Follow this link for more information on Triage career opportunities (Source: Support for I...

The Double Helix by James D Watson – review

Guardian Unlimited Science — Fri, 20 Jan 2012 12:30:00 +0100

Given his part in discovering the structure of DNA and his writing flair, we can perhaps forgive Watson his lack of modestyWe're now reading God and the New Physics by Paul Davies, which Tim will review on Friday 16 MarchThe Double Helix opens with the words: "I have never seen Francis Crick in a modest mood." I have never seen James D Watson in a modest mood, either. He is not an innately modest person. In his later years he would consent to press briefings – usually on important anniversaries – and then, with long pauses and enigmatic mumbles, say almost nothing.This was not because he was self-effacing or disliked controversy. He would say almost nothing, one sensed, because he couldn't be bothered with stupid questions from stupid people. He has made it clear more than once that th...

Physician Assistant Education: Trends for the Future

Physicians Practice — Fri, 20 Jan 2012 12:00:00 +0100

While the demographics of the physician assistant student population are changing, the quality of the graduate PA remains solid. (Source: Physicians Practice)

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Women and the maths problem | Helen Powell

Guardian Unlimited Science — Fri, 20 Jan 2012 10:30:00 +0100

The researchers are right: girls are held back by preconceptions about maths being boring, not a 'stereotype threat' lack of beliefWomen's underachievement in maths may not be due to their poor self-image in the subject, a new report suggests. Researcher Dr Gijsbert Stoet at the University of Leeds says that the so-called "stereotype threat" theory – which holds that women perform worse than men because they expect to do badly – "does not stand up to scrutiny".Earlier research had serious flaws, he says, with improper use of statistical techniques and methodology. Clearly those who carried out this research need to review their own competence in maths. Stoet believes the gender gap may simply be that men and women have different interests from an early age, and says the answer to getti...

Clinical and histological changes associated with corticosteroid therapy in IgG4-related tubulointerstitial nephritis

Modern Rheumatology — Fri, 20 Jan 2012 07:47:03 +0100

Conclusions Our study shows that persistent renal insufficiency associated with macroscopic atrophy and microscopic fibrosis is not so rare in IgG4-related TIN. Pathologically, the behavior of regulatory T cells during the clinical course is quite similar to that of IgG4-positive plasma cells, and the behavior pattern of those cells is distinctive. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s10165-011-0589-2Authors Ichiro Mizushima, Division of Rheumatology, Department of Internal Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Kanazawa, Ishikawa 920-8640, JapanKazunori Yamada, Division of Rheumatology, Department of Internal Medicine, Kanazawa University Graduate School of Medicine, 13-1 Takara-machi, Ka...

Ocular circulatory responses to exhaustive exercise in humans

European Journal of Applied Physiology — Fri, 20 Jan 2012 07:05:32 +0100

Abstract It is unclear whether exhaustive dynamic exercise increases ocular blood flow, although we have reported that submaximal exercise increases ocular blood flow. We hypothesized that ocular blood flow decreases at exhaustion, since exhaustion causes hyperventilation, which induces a reduction in PaCO2. To test this hypothesis, ocular blood flow, blood pressure, and respiratory measurements were made in 12 healthy male subjects during cycle ergometer exercise at 75% of maximal heart rate, until exhaustion. Blood flows in the retinal and choroidal vasculature (RCV), the superior temporal retinal arteriole (STRA), and the superior nasal retinal arteriole (SNRA) were measured with the aid of laser-speckle flowgraphy every 3 min during the exercise. The conductance in...

Is visual inspection with acetic acid better than cervical cytology to screen women ≥40 years of age for carcinoma cervix? A cross-sectional study on proportion of screen-positive women (by VIA and cervical cytology) having CIN II/III lesion on cervical biopsy: difference between two age groups and among screening methods

Archives of Gynecology and Obstetrics — Fri, 20 Jan 2012 07:05:20 +0100

Conclusion Cytological screening is less sensitive in women ≥40 years while VIA has a uniform sensitivity for both groups. Content Type Journal ArticleCategory Gynecologic OncologyPages 1-6DOI 10.1007/s00404-012-2228-3Authors Subhankar Dasgupta, Department of Gynaecology and Obstetrics, Department of Pathology, Institute of Post Graduate Medical Education and Research (IPGMER), 273, Harinibash, Nungi Station Pally, P.O. Batanagar, DT. 24 PG(S), Kolkata, 743313 West Bengal, IndiaSudhindramohan Bhattacharya, Department of Gynaecology and Obstetrics, K.P.C Medical College and Hospital, Kolkata, 32 West Bengal, India Journal Archives of Gynecology and ObstetricsOnline ISSN 1432-0711Print ISSN 0932-0067 (Source: Archives of Gynecology and Obstetrics)

Conventional or navigated total knee arthroplasty affects sagittal component alignment

Knee Surgery, Sports Traumatology, Arthroscopy — Fri, 20 Jan 2012 07:04:50 +0100

Conclusions Targeted sagittal prosthetic alignments of TKA achieved using the conventional technique and various navigation systems differed in elderly women. The use of different reference points on the distal femoral condyle for navigation systems resulted in different alignment in the sagittal plane. This study showed that alignment tendencies are similar in men and women. Level of evidence Prognostic studies, IV. Content Type Journal ArticleCategory KneePages 1-6DOI 10.1007/s00167-012-1889-6Authors Ryo Sugama, Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahimachi Abeno-ku, Osaka, 545-8585 JapanYukihide Minoda, Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, 1...

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The relationship of anterior and rotatory laxity between surgical navigation and clinical outcome after ACL reconstruction

Knee Surgery, Sports Traumatology, Arthroscopy — Fri, 20 Jan 2012 07:04:49 +0100

Conclusion Although AP and rotational laxities vary largely among the patients, and AP and rotational stabilization are successfully achieved immediately after ACL reconstruction, intraoperative AP and rotational laxity measured by the navigation system did not influence the postoperative AP and rotational laxities after ACL reconstruction. Level of evidence III. Content Type Journal ArticleCategory KneePages 1-7DOI 10.1007/s00167-012-1900-2Authors Shingo Ohkawa, Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, 734-8551 JapanNobuo Adachi, Department of Orthopedic Surgery, Graduate School of Biomedical Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima...

Mechanistic analysis of the antitumor efficacy of human natural killer cells against breast cancer cells

Breast Cancer Research and Treatment — Fri, 20 Jan 2012 07:04:07 +0100

Abstract We investigated the role of human natural killer (NK) cells in the peripheral blood (PB) and liver in controlling breast cancer. The proportion of NK cells among liver mononuclear cells was significantly higher than among PB mononuclear cells. Liver NK cells inductively expressed higher levels of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) than PB NK cells in response to interleukin-2 (IL-2). Liver NK cells displayed higher cytotoxicity against various breast cancer cell lines (MDA-MB231, MDA-MB453, MDA-MB468, and MCF-7) after IL-2 stimulation than did PB NK cells. Anti-HER2 monoclonal antibody (mAb) promoted the cytotoxicity of both the types of NK cells toward HER2-expressing cell lines. All breast cancer cell lines highly expressed death-ind...

Enoxaparin may not reduce death rate for acutely ill

Modern Medicine — Fri, 20 Jan 2012 05:00:00 +0100

The use of enoxaparin on hospitalized, acutely ill patients wearing elastic stockings with graduated compression did not reduce the rate of death when compared with the use of graduated compression stockings alone, according to a study published December 29, 2011, in the New England Journal of Medicine (Source: Modern Medicine)

Joaquín María Albarrán y Domínguez (1860-1912). In the Centenary of His Death.

Actas Urologicas Espanolas — Fri, 20 Jan 2012 05:00:00 +0100

CONCLUSIONS: An eminent urologist, not only because of the importance of his word but also due to design of the nail that carries his name as well as different urological eponyms, his human stature, his category as an investigator and his scientific excellence. Because of presence in Paris, the most important Spanish urologists were prepared at his side, this contributing to the rebirth and boom of the Urology in Spain. PMID: 22266259 [PubMed - as supplied by publisher] (Source: Actas Urologicas Espanolas)