MedWorm: Lessons

13 Lessons for Aging Well - Lesson 3

Psychology Today Depression Center — Thu, 09 Feb 2012 03:44:19 +0100

Lesson Three: Live in Moderation - Aging Our WayThis is the third in a 13- post series on living well, adapted from Aging Our Way: Lessons for Living from 85 and BeyondFind a ninety-something and watch closely.read more (Source: Psychology Today Depression Center)

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A Systematic Review of Physical Activity Interventions in Hispanic Adults

Experimental Diabetes Research — Wed, 08 Feb 2012 19:49:39 +0100

Healthy People 2020 aims to achieve health equity, eliminate disparities, and improve the health of all groups. Regular physical activity (PA) improves overall health and fitness and has the capability to reduce risk for chronic diseases. Identifying barriers which relate to the Hispanic population is important when designing PA interventions. Therefore, the purpose was to review existing PA interventions targeting Hispanic adults published between 1988 and 2011. This paper was limited to interventions which included more than 35% Hispanic adults (n=20). Most of the interventions were community based (n=16), although clinical, family-based, and faith-based settings were also represented. Interventions incorporated theory (n=16), with social cognitive theory and transtheoretical model being...

Love Lessons No. 2: Love Takes Work (Sex Does, Too!)

Psychology Today Relationships Center — Wed, 08 Feb 2012 10:38:37 +0100

In last week's post, I introduced the idea that a good relationship needs to have space for each individual person. Two separate people come together to make something new that is more than either could have alone. Today, I want to build on that idea by suggesting that there are actually three entities in any good relationship: you, me, and the relationship itself.read more (Source: Psychology Today Relationships Center)

The Latest Developments Of Specific-Spectrum, Anti-Staphyloccal Agents Using In-vitro, In-vivo And Human Clinical Data, 5-6 March 2012, London

Health News from Medical News Today — Wed, 08 Feb 2012 08:00:00 +0100

Now in its 14th year, Superbugs & Superdrugs is a well established antibacterial event that promises to be the perfect forum for networking and problem solving with senior industry executives from the pharmaceutical sector. The event will be held on the 5&6 of March at the Copthorne Tara Hotel, London and will be made up of case-study focused presentations, highlighting success stories and lessons to be learnt... (Source: Health News from Medical News Today)

Von Willebrand disease: Clinical and laboratory lessons learned from the large von Willebrand disease studies

American Journal of Hematology — Wed, 08 Feb 2012 05:00:00 +0100

AbstractDuring the past 25 years, our knowledge concerning the pathogenesis, diagnostic strategies and treatment of von Willebrand disease (VWD) has increased significantly. Following the immunological differentiation of factor VIII (FVIII) and von Willebrand factor (VWF) in the 1970s and the cloning of the FVIII and VWF genes in the mid‐1980s, substantial progress has been made in our understanding of this, the most common inherited bleeding disorder. We now recognize that VWD represents a range of genetic diseases all with the clinical endpoint of increased mucocutaneous bleeding. The molecular pathology of Type 2 and Type 3 VWD is now comprehensively documented and involves rare sequence variants at the VWF locus. In contrast, the genetic causation of Type 1 disease remains incomplete...

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Evolution of Sensory Development – Lessons from the Lateral Line

Karger Publishers — Tue, 07 Feb 2012 23:00:00 +0100

Brain Behav Evol 2012;79:73–74 (DOI:10.1159/000335696) (Source: Karger Publishers)

Newest Archives Applied SAM: Lessons From Laboratory Drug Testing Surveys

CAP Important Announcements and News — Tue, 07 Feb 2012 17:12:00 +0100

Authored by expert Stacy E.F Melanson, MD, PhD, FCAP, this SAM will demonstrate how providing interpretations for immunoassays assists clinicians. (Source: CAP Important Announcements and News)

Critical narrative review to identify educational strategies promoting physical activity in preschool

Obesity Reviews — Tue, 07 Feb 2012 10:44:22 +0100

SummaryThe aim of this narrative review is critically to evaluate educational strategies promoting physical activity that are used in the preschool setting in the context of obesity prevention programmes. Literature search was conducted between April and August 2010 in English and German databases (PubMED, PsychINFO, PSYNDEX, ERIC, FIS Bildung). Outcomes considered were time and intensity of physical activity, motor skills or measures of body composition. A total of 19 studies were included. Ten studies added physical activity lessons into their curriculum, one study provided more time for free play, eight studies focused on the social and play environment. Studies reporting positive outcomes implemented physical activity sessions that lasted at least 30 min d−1. Several studies show...

Developing community-based preventive interventions in Hong Kong: a description of the first phase of the Family Project

BMC Public Health - Latest articles — Tue, 07 Feb 2012 03:50:35 +0100

Conclusions: This work has public health significance because of the global importance of parent-child relationships as a risk-factor for many outcomes in adulthood, the need to develop interventions with strong evidence of effectiveness to populations outside the West, the potential application of our interventions to universal populations, and characteristics of the interventions that promote dissemination, including minimal additional costs for delivery by community agencies, and high acceptability to participants. (Source: BMC Public Health - Latest articles)

Discrepancies Between Reported Self-Monitored Blood Glucose Results and Point-of-Care Hemoglobin A1c in Children with Diabetes: Lessons to Be Learned

Diabetes Technology — Mon, 06 Feb 2012 21:52:52 +0100

Diabetes Technology & Therapeutics , Vol. 0, No. 0. (Source: Diabetes Technology)

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Translating standards into practice: Experience and lessons learned at the Department of Veterans Affairs

ICMCC: The International Council on Medical and Care Compunetics — Mon, 06 Feb 2012 16:54:26 +0100

Source: Bouhaddou O et al, Journal of Biomedical Informatics, 2012 Content: The increased need for interoperable electronic health records in health care organizations underscores the importance of standards. The US Department of Veterans Affairs (VA) has a long history of developing and adopting various types of health care data standards. The authors present in detail [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)

Terminally ill prof teaches end-of-life lessons

Health News: CBSNews.com — Mon, 06 Feb 2012 14:28:04 +0100

University of Missouri educator using web to share cancer experience, says he's not wasting his time fighting the cancer (Source: Health News: CBSNews.com)

Video: Prof. David Oliver's life lessons

Health News: CBSNews.com — Mon, 06 Feb 2012 14:15:27 +0100

Prof. David Oliver talks to Charlie Rose and Erica Hill about his experience in dealing with a terminal illness after years of teaching others how to cope with death and dying. (Source: Health News: CBSNews.com)

Video: Learning how to live, and die

Health News: CBSNews.com — Mon, 06 Feb 2012 14:11:03 +0100

A professor who spent decades teaching others how to care for dying patients is now terminally ill himself. CBS News national correspondent Lee Cowan reports on how he's still teaching lessons on life and death. (Source: Health News: CBSNews.com)

Lessons from the Court: What Basketball Can Teach Us About Overcoming Social Anxiety

Psychology Today Anxiety Center — Sun, 05 Feb 2012 22:56:02 +0100

Sports represent the ultimate in reality television. In addition to the competition, there are the personal stories behind the events. This background adds a mythical subtext that exemplifies why athletes are sometimes seen as heroes. read more (Source: Psychology Today Anxiety Center)

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El Monte City School District in More than Decade-Long Process to Promote Healthy Lifestyles

RWJF News Digest - Childhood Obesity — Sat, 04 Feb 2012 05:00:00 +0100

The menu items available to El Monte City School District students on a recent Wednesday were a far cry from the staples that for years dominated school lunches - offerings like sloppy joes and tater-tots. The change is the product of a more-than-decade-long effort to bring healthier options to the children of the K-8 school district. Combined with a hefty nutritional curriculum that has pervaded regular classroom lessons, the district has landed several prestigious awards and brought it closer to creating a healthier student population, officials said. (Source: RWJF News Digest - Childhood Obesity)

Lives: Dazed and Confused

NYT Health — Fri, 03 Feb 2012 22:35:43 +0100

How skipping school in late-’70s New York became a lesson in the costs of dropping out. (Source: NYT Health)

PIP implants: Taking the right decision and lessons to be learnt

OnMedica Views — Fri, 03 Feb 2012 05:00:00 +0100

Fazel Fatah, president of BAAPS, discusses the controversy and highlights the guidelines for health professionalsRelated items from OnMedicaWelsh NHS to pay for PIP implant removal and replacementGovernment sets scope for cosmetic surgery reviewsAll women with defective breast implants entitled to surgical assessment and removal Latest advice on PIP implantsRegulator moves to reassure UK women after breast implant scare (Source: OnMedica Views)

Bias in Observational Studies of Prevalent Users: Lessons for Comparative Effectiveness Research From a Meta-Analysis of Statins

American Journal of Epidemiology — Fri, 03 Feb 2012 05:00:00 +0100

Randomized clinical trials (RCTs) are usually the preferred strategy with which to generate evidence of comparative effectiveness, but conducting an RCT is not always feasible. Though observational studies and RCTs often provide comparable estimates, the questioning of observational analyses has recently intensified because of randomized-observational discrepancies regarding the effect of postmenopausal hormone replacement therapy on coronary heart disease. Reanalyses of observational data that excluded prevalent users of hormone replacement therapy led to attenuated discrepancies, which begs the question of whether exclusion of prevalent users should be generally recommended. In the current study, the authors evaluated the effect of excluding prevalent users of statins in a meta-analysis ...

Regulation of Cell Physiology and Pathology by Protein S-Glutathionylation: Lessons Learned from the Cardiovascular System

Antioxidants and Redox Signaling — Thu, 02 Feb 2012 20:21:24 +0100

Antioxidants & Redox Signaling Mar 2012, Vol. 16, No. 6: 524-542. (Source: Antioxidants and Redox Signaling)

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Scorpion Armor Inspires Sand-Resistant Surfaces

Scientific American - Official RSS Feed — Thu, 02 Feb 2012 03:20:08 +0100

It’s tough to be a machine in the desert: particles of dirt and sand work their way into moving parts, where they abrade turbines, motors, pipes and other equipment. To avoid this costly wear and tear, researchers are taking lessons from a desert native: the yellow fat-tail scorpion. [More] (Source: Scientific American - Official RSS Feed)

Love Lessons #1: Let There Be Space in Your Togetherness

Psychology Today Relationships Center — Wed, 01 Feb 2012 15:56:52 +0100

The Beatles sang it and we want to believe it: "All you need is love, love. Love is all you need." Sounds good, right? I'd just always hoped there would be a few more lines to the song so I could figure out how you keep it going and keep it going well!read more (Source: Psychology Today Relationships Center)

[Comment] Don't pick the loser: lessons from the GeparQuinto trial

The Lancet Oncology — Wed, 01 Feb 2012 05:00:00 +0100

In The Lancet Oncology, Michael Untch and colleagues report the first efficacy results from the GeparQuinto (GBG 44) study, a randomised phase 3 trial of lapatinib versus trastuzumab in combination with neoadjuvant anthracycline-based and taxane-based chemotherapy. 620 women with HER2-positive operable or locally advanced breast cancer were randomly assigned to receive lapatinib (a tyrosine-kinase inhibitor of HER1 and HER2) or trastuzumab (a monoclonal antibody to the HER2 receptor), concurrent with a planned regimen of four cycles of an anthracycline (epirubicin 90 mg/m2 plus cyclophosphamide 600 mg/m2) followed by four cycles of a taxane (docetaxel 100 mg/m2). (Source: The Lancet Oncology)

Lessons From the Housing Bubble

Nurse Leader — Wed, 01 Feb 2012 05:00:00 +0100

The more we examine the impact of the mortgage crises on our economic well-being, the more critical becomes a parallel issue known as the healthcare bubble. The growing costs of providing healthcare and the increases in premiums, copays, and deductibles create a gloom and doom scenario. Our middle class cannot afford the increase in taxes that the public sector may need, nor can we absorb any more costs in our broken healthcare system. (Source: Nurse Leader)

Why New Managers Fail: What Can We Do to Prevent It?

Nurse Leader — Wed, 01 Feb 2012 05:00:00 +0100

We have long had challenges in nursing to groom and persuade staff nurses to pursue and accept management roles. Staff nurses often comment that managers have difficult and pressure-filled jobs that involve long work hours and around-the-clock accountability. To be sure, middle managers feel the constant squeeze between being a member of administration and needing to support the needs of unit-level staff. The tension of this vice is wearing and often visible to those who interact with the managers, leading to the sense that the job is less flexible and less desirable than a staff role. It is no wonder that organizations face difficult odds to plan and orchestrate succession in nursing management roles. (Source: Nurse Leader)

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The Garden Party

Journal of the American College of Radiology : JACR — Wed, 01 Feb 2012 05:00:00 +0100

But it's all right now, I learned my lesson well. You see, you can't please everyone, so you got to please yourself. —Rick Nelson I am fortunate to receive e-mails from readers commenting on my monthly editorials. Most of them are complimentary. Some even tell me what I left out or how I could have written the piece better (sometimes they are right). Most months, I get at least a couple of these critiques. Every once in a while, I am surprised to get as many as 5 or 6. To me, that qualifies an editorial as a cult classic, since I figure most radiologists are too busy to read, let alone write. (Source: Journal of the American College of Radiology : JACR)

The Verriest Lecture: Color lessons from space, time and motion

Journal of the Optical Society of America A — Wed, 01 Feb 2012 05:00:00 +0100

The appearance of a chromatic stimulus depends on more than the wavelengths composing it. The scientific literature has countless examples showing that spatial and temporal features of light influence the colors we see. Studying chromatic stimuli that vary over space, time, or direction of motion ... (Source: Journal of the Optical Society of America A)

Training community care workers to provide comprehensive TB/HIV/PMTCT integrated care in KwaZulu‐Natal: lessons learnt

Tropical Medicine and International Health — Wed, 01 Feb 2012 05:00:00 +0100

Conclusion The findings of this study suggest higher uptake of TB and STI symptoms screening, TB contact tracing and home based HCT in the intervention clusters. This study suggests that up‐skilling CCWs could be one avenue to enhance TB/HIV case finding, TB contact tracing and linkages to care. (Source: Tropical Medicine and International Health)

Public health services, an essential determinant of health during crisis. Lessons from Cuba, 1989–2000

Tropical Medicine and International Health — Wed, 01 Feb 2012 05:00:00 +0100

AbstractDuring the 1990s, Cuba was able to overcome a severe crisis, almost without negative health impacts. This national retrospective study covering the years 1989–2000 analyses the country’s strategy through essential social, demographic, health process and health outcome indicators. Gross domestic product (GDP) diminished by 34.76% between 1989 and 1993. In 1994 slow recuperation started. During the crisis, public health expenses increased. The number of family doctors rose from 9.22 to 27.03 per 104 inhabitants between 1989 and 2000. Infant mortality rate and life expectancy exemplify a series of health indicators that continued to improve during the crisis years, whereas low birth weight and tuberculosis incidence are among the few indicators that suffered deterioration. GDP is ...

Lessons learned in developing community mental health care in North America.

World Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Drake RE, Latimer E Abstract This paper summarizes the findings for North America of the WPA Task Force on Steps, Obstacles and Mistakes to Avoid in the Implementation of Community Mental Health Care. Community mental health has evolved over five decades in the United States and Canada. The United States has led the world in innovation and spending, but provide variable quality of care; Canada has steadily developed a more uniform public health system for less cost. Lessons learned from North America include: team-based approaches and other evidence-based practices, when implemented with high fidelity, can improve outcomes in routine mental health care settings; recovery ideology and peer support enhance care, though they have not been studied rigorously; effective communi...

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Neonatal herpes: what lessons to learn.

Hong Kong Med J — Wed, 01 Feb 2012 05:00:00 +0100

We report two illustrative neonatal cases of herpesvirus infections with vesicular rashes. Such babies may be remarkably asymptomatic. A high index of suspicion leading to a prompt diagnosis, timely quarantine measures, and institution of antiviral treatment are pivotal for desirable outcomes. PMID: 22302914 [PubMed - in process] (Source: Hong Kong Med J)

Mastering improvement science skills in the new era of quality and safety: the Veterans Affairs National Quality Scholars Program

Journal of Evaluation in Clinical Practice — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions The VA National Quality Scholars program continues to nurture and develop leaders for the new millennium focusing on interprofessional education. The nations' health care systems need strong interdisciplinary leaders in advanced quality improvement science who are dedicated to improving the overall quality of health and health care. (Source: Journal of Evaluation in Clinical Practice)

Biomed Analysis: Learning from India's polio success

SciDev.Net — Tue, 31 Jan 2012 16:15:35 +0100

India's carefully targeted strategy against polio holds lessons for other countries, and for other diseases, argues Priya Shetty. (Source: SciDev.Net)

Military Proposes Budget Cuts, Protects Research Programs

Public Policy Reports — Tue, 31 Jan 2012 12:37:03 +0100

The Department of Defense has released a blueprint for how it would reduce its spending by $259 billion over the next five years. The reductions would bring the department’s budget in line with the spending caps mandated by last year’s deficit reduction agreement. At a press conference to announce the plan, the Secretary of Defense and the Chairman of the Joint Chiefs of Staff defended the proposal as a carefully crafted, balanced package. Secretary Panetta noted, “while some programs are eliminated or delayed, others are increased. The budget looks to re-shape the military to be more agile, quick and flexible that incorporates the lessons learned in 10 years of war.” The proposed budget for fiscal year (FY) 2013 would be one percent less than current spending; th...

Sweet summer cherries and fatal ileus: a story from the past

Forensic Science, Medicine, and Pathology — Tue, 31 Jan 2012 07:05:57 +0100

Content Type Journal ArticleCategory Lessons from the MuseumPages 1-2DOI 10.1007/s12024-012-9313-6Authors Slobodan Nikolić, Institute of Forensic Medicine, School of Medicine, University of Belgrade, 31a Deligradska Str., 11000 Belgrade, SerbiaVladimir Živković, Institute of Forensic Medicine, School of Medicine, University of Belgrade, 31a Deligradska Str., 11000 Belgrade, Serbia Journal Forensic Science, Medicine, and PathologyOnline ISSN 1556-2891Print ISSN 1547-769X (Source: Forensic Science, Medicine, and Pathology)

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Therapy of lupus nephritis: lessons learned from clinical research and daily care to patients

Arthritis Research and Therapy — Tue, 31 Jan 2012 05:00:00 +0100

Despite numerous randomized clinical trials over the last three decades for identifying the optimal treatment option for lupus nephritis, renal involvement still significantly impacts the survival and quality of life of patients with lupus and the search for the ideal immunosuppressive regimen is far from complete. The purpose of this review is to summarize the major recent achievements in the field. More specifically, the following topics will be discussed: intravenous cyclophosphamide versus mycophenolate mofetil (MMF) for induction; azathioprine versus MMF for maintenance; targeted therapies. The review will address clues for optimal global care, such as the need for complete initial evaluation, the importance of patient education, the unmasking of non-compliance to therapy, the reason ...

Lessons from ALL-REZ BFM 90: Therapy for Childhood Leukemia Based on Timing and Site of Relapse

Current Hematologic Malignancy Reports — Mon, 30 Jan 2012 16:04:36 +0100

Content Type Journal ArticleCategory Invited CommentaryPages 1-2DOI 10.1007/s11899-011-0112-zAuthors Michael E. Rytting, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA Journal Current Hematologic Malignancy ReportsOnline ISSN 1558-822XPrint ISSN 1558-8211 (Source: Current Hematologic Malignancy Reports)

Impulse control and criminal responsibility: Lessons from neuroscience. - Penney S.

SafetyLit: All (Unduplicated) — Mon, 30 Jan 2012 15:32:08 +0100

Almost all of the world's legal systems recognize the "M'Naghten" exception to criminal responsibility: the inability to appreciate the wrongfulness of action. This exception rests on the assumption that punishment is morally justified only if the defendan... (Source: SafetyLit: All (Unduplicated))

Having Students at My Medical Practice Provides Lessons in Liability

Physicians Practice — Mon, 30 Jan 2012 12:00:00 +0100

I fully understand that those who wish to pursue clinical jobs need time with actual patients …but I still need to protect my patients and my practice. (Source: Physicians Practice)

CBO: Medicare demos didn't save much money

American Medical News - GOVERNMENT — Mon, 30 Jan 2012 12:00:00 +0100

A report details the lessons learned from Medicare demonstration projects that tried to reduce costs and improve quality of care. (Source: American Medical News - GOVERNMENT)

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Nigeria: Polio - Lessons From India

AllAfrica News: Polio — Mon, 30 Jan 2012 08:07:31 +0100

[Daily Trust] According to World Health Organization's (WHO) News release titled 'One year polio free in India is a major achievement; the country was once the world's epicentre of polio' on 12 January 2012 -India appears to have interrupted wild poliovirus transmission, completing one year without polio since its last case, in a 2-year-old girl in the state of West Bengal, on 13 January 2011. (Source: AllAfrica News: Polio)

Understanding risk in asymptomatic carotid stenosis: Lessons from patients' preferences

Neurology — Mon, 30 Jan 2012 05:00:00 +0100

(Source: Neurology)

Lessons From ZocDoc, a Health Tech Start-Up That Works

RWJF News Digest - Quality/Equality — Mon, 30 Jan 2012 05:00:00 +0100

ZocDoc, an oddly named Web service for scheduling appointments with doctors, started in New York in 2007 and has been growing at a torrid pace. (Source: RWJF News Digest - Quality/Equality)

Are there lessons to be learned from a more scientific approach to mental condition defences?

International Journal of Law and Psychiatry — Mon, 30 Jan 2012 05:00:00 +0100

Authors: Claydon L Abstract The timing of the English Law Commission's consideration of reform to the law of insanity coincides with increasing scientific and in particular neuroscientific understanding of the brain. The work of researchers is leading to a greater comprehension of what had been termed irresistible impulses to commit crime and of the impact of brain damage, particularly evidence of brain lesions and frontal lobe damage on behaviour. There remain problems in establishing causal relationships which might diminish or eliminate criminal responsibility for crimes committed by those suffering from pre existing mental conditions at the time they commit a criminal offence. This is especially the case where those mental conditions are of short duration. However, the law shou...

Allergy and sports in children

Pediatric Allergy and Immunology — Sun, 29 Jan 2012 11:08:48 +0100

To cite this article: Del Giacco SR, Carlsen K‐H, Du Toit G. Allergy and sports in children. Pediatric Allergy Immunol 2012: 23: 11–20.AbstractPhysical activity is beneficial for children with positive outcomes for mental and physical well‐being. Allergic conditions unique to the sporting arena may serve as an impediment to participation in physical activity for allergic children. A common example is exercise‐induced asthma; less common activity‐related allergic conditions include food‐dependent exercise‐induced anaphylaxis, exercise‐induced anaphylaxis, and exercise‐induced urticaria. Allergic children may also be at risk of allergic reactions when exposed to allergens that are more commonly found in the sports environment, e.g., latex, sports drinks, and medications suc...

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Lessons learned * School-based health centers break through barriers to medical care [NEWS AND FEATURES]

AAP News — Sun, 29 Jan 2012 05:00:00 +0100

(Source: AAP News)

Safety Saturday

About.com Pediatrics — Sat, 28 Jan 2012 09:51:23 +0100

Parents can certainly learn a lesson from some of these accidents and tragedies, such as that a mild winter equals thin ice on most ponds, which means you shouldn't go for a stroll on the ice with your family. Also, gun powder and kids aren't a good mix....Read Full Post (Source: About.com Pediatrics)

A working life: the geneticist

Guardian Unlimited Science — Fri, 27 Jan 2012 23:02:30 +0100

Joe Rainger might still have been a chef, but for a degree change that took him out of the kitchen and plunged him into a world of DNA researchPeople born with abnormal eyes could – within our lifetime – benefit from replacements that match their own DNA, thanks to research by scientists like Joe Rainger.The 35-year-old geneticist is researching a mutation in human genes that causes microphthalmia (one or both eyes abnormally small), anophthalmia (absence of one or both eyes), and coloboma (a gap in the structure of the eye). The conditions are recessive; which means you need both parents to carry the defective gene for the conditions to appear. They are therefore most common in families where first cousins marry.Rainger, who works at the Medical Research Council's human genetics unit ...

Saving Mothers' Lives: The Continuing Benefits for Maternal Health From the United Kingdom (UK) Confidential Enquires Into Maternal Deaths

Seminars in Perinatology — Fri, 27 Jan 2012 22:41:27 +0100

The actions that have followed the recommendations of successive publications of the UK Confidential Enquiries into Maternal Deaths have helped save mothers' lives and reduced ill health and morbidity. Through the implementation of their recommendations, they have helped improve access to, and the quality of, the maternity care provided for all pregnant women in the United Kingdom. The enquires help review, assess, and identify the underlying remediable factors that contributed to mothers' deaths and aggregate the lessons learned to make recommendations to develop services that help overcome many of the barriers to safe, high-quality maternity care, which vulnerable women continue to face. This chapter provides a short summary of the positive contributions the successive reports on Confide...

Alterations in the contractile phenotype of the bladder: lessons for understanding physiological and pathological remodelling of smooth muscle

Journal of Cellular and Molecular Medicine — Fri, 27 Jan 2012 21:50:25 +0100

Abstract• Introduction• Alterations in bladder contractility with normal development• Assessment of bladder function in genetically modified mice• A whole organ perspective on the bladder’s response to pBOO‐ Clinical observations• Experimental observations• In vivo measures of pBOO in a rabbit model• Relating muscle strip studies to whole organ function• Myosin light chain phosphorylation• Regulation of myosin light chain de‐phosphorylation• Alterations in the thick contractile filaments‐ SM1 and SM2 isoforms‐ SM‐B and SM‐A isoforms• Regulatory light chain• Alterations in the thin contractile filaments• Alterations in tension transfer complexThe contractile properties of the urinary bladder are changed by the condition...

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Why are people friendly? | Andrew Brown

Guardian Unlimited Science — Fri, 27 Jan 2012 17:28:49 +0100

Without selection between competing groups, the advantages of co-operation are not great enough to make it spreadThis week's Nature has a report on how hunter-gatherers co-operate, which shows the way in which the scientific study of altruism has moved on since The Selfish Gene. That book popularised two explanations for our unselfish instincts and behaviour. The first, and nowadays obvious, reason is that it causes genes associated with it to spread: if I am helpful to my relatives, my descendants will have more relatives. The second is Robert Trivers's model of "reciprocal altruism": over time, co-operation pays, and nice guys finish first – providing that they are also sufficiently nasty to the nasty guys.Both these explanations still hold, but they are not enough, by themselves or in...

FDA’s Grace McNally to Appear at ISPE Facilities Conference

PRWeb: Medical Pharmaceuticals — Fri, 27 Jan 2012 06:33:34 +0100

Event to explore lessons learned from FDA 483s in tracks focused on Biotech, Oral Solid Dosage Processing and Containment, and Process Validation.(PRWeb January 26, 2012)Read the full story at http://www.prweb.com/releases/2012/1/prweb9141012.htm (Source: PRWeb: Medical Pharmaceuticals)

Popular intoxicants: what lessons can be learned from the last 40 years of alcohol and cannabis regulation?

Journal of Psychopharmacology — Fri, 27 Jan 2012 05:00:00 +0100

In this paper we discuss the relative physical, psychological and social harms of the two most frequently used intoxicant drugs in the UK, namely cannabis and alcohol. Over the past 40 years, the use of both drugs has risen significantly with differential consequences. It is argued that increased policing of cannabis use under the current drug classification system will lead to increased criminalization of young people, but is unlikely to significantly reduce the rates of schizophrenia and psychosis. In comparison, increases in alcohol drinking are related to significant increases in liver cirrhosis hospital admissions and mortality, at a time when mortality rates from other major causes are on the decline. A recent expert-led comparison of the health and social harms to the user and to ot...

Comparing Poly (ADP-Ribose) Polymerase Inhibitors With Standard Chemotherapy in BRCA-Mutated, Recurrent Ovarian Cancer: Lessons Learned From a Negative Trial [EDITORIALS]

Journal of Clinical Oncology — Fri, 27 Jan 2012 05:00:00 +0100

(Source: Journal of Clinical Oncology)

The West Virginia Prescription Drug Abuse Quitline: Challenges and Lessons Learned From Running a Remote Quitline

Health Promotion Practice — Fri, 27 Jan 2012 05:00:00 +0100

This article describes the process evaluation of the WVPDAQ and outlines both the positive findings and challenges faced by the WVPDAQ. Lessons learned and future recommendations for remote quitline endeavors are also presented. It is hoped that the experiences and information regarding the WVPDAQ presented can provide best-practice insight for public health practitioners and evaluation personnel who are considering using alternative technologies to deliver quitline services. (Source: Health Promotion Practice)

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Catalyzing Transdisciplinary Studies in Public Health: A College Health Survey and Data Platform

Health Promotion Practice — Fri, 27 Jan 2012 05:00:00 +0100

This article describes a process designed to promote better understanding of the interrelatedness of health behaviors and outcomes through a multidimensional Internet-based health survey aimed at undergraduate college students. In addition, we describe a data-sharing platform whereby faculty and students from across disciplines may access the raw data for a variety of uses. An analysis is performed illustrating a syndemic between binge drinking, sexually transmitted diseases, and using alcohol or drugs prior to sexual intercourse. Potential applications of the multidomain survey are discussed, as well as lessons learned and limitations of this approach. (Source: Health Promotion Practice)

Lessons from the past and charting the future of marine natural products drug discovery and chemical biology.

Chemistry and Biology — Fri, 27 Jan 2012 05:00:00 +0100

Authors: Gerwick WH, Moore BS Abstract Marine life forms are an important source of structurally diverse and biologically active secondary metabolites, several of which have inspired the development of new classes of therapeutic agents. These success stories have had to overcome difficulties inherent to natural products-derived drugs, such as adequate sourcing of the agent and issues related to structural complexity. Nevertheless, several marine-derived agents are now approved, most as "first-in-class" drugs, with five of seven appearing in the past few years. Additionally, there is a rich pipeline of clinical and preclinical marine compounds to suggest their continued application in human medicine. Understanding of how these agents are biosynthetically assembled has accelerated in...

Twenty-five years of research and new beginnings

Applied Nursing Research : ANR — Fri, 27 Jan 2012 02:54:20 +0100

This volume marks the 25th anniversary of Applied Nursing Research (ANR). In these past two and a half decades, there has been a dramatic increase in the nursing knowledge developed and disseminated both in the United States and globally. Funding for nurse scientists also has increased, and these scientists are recognized as full members of the academic community. As part of this volume, in tribute to the scholarship of the past and the inherent lessons for future researchers, we will profile some of the most significant studies published in ANR. (Source: Applied Nursing Research : ANR)

Lessons from Thumbsucking, The Earliest Addiction

Psychology Today Parenting Center — Fri, 27 Jan 2012 00:44:43 +0100

What helps kids to cease sucking their fingers or thumbs? These same principles can prove useful for grownups who want to overcome mistaken-things-we-put-in-our-mouths like excessive food, alcohol and drugs, or cigarettes. read more (Source: Psychology Today Parenting Center)

Creutzfeldt-Jakob disease and mad cows: lessons learnt from yeast cells.

Swiss Medical Weekly — Thu, 26 Jan 2012 09:24:02 +0100

Authors: Hofmann J, Wolf H, Grassmann A, Arndt V, Graham J, Vorberg I Abstract Transmissible spongiform encephalopathies are fatal neurodegenerative diseases that affect mammals including humans. The proteinaceous nature of the infectious agent, the prion, and its propagation, challenge established dogmas in biology. It is now widely accepted that prion diseases are caused by unconventional agents principally composed of a misfolded host-encoded protein, PrP. Surprisingly, major break-throughs in prion research came from studies on functionally unrelated proteins in yeast and filamentous fungi. Aggregates composed of these proteins act as epigenetic elements of inheritance that can propagate their alternative states by a conformational switch into an ordered ß-sheet rich polymer j...

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Perforation of Transverse Colon: A Catastrophic Complication of Uterine Artery Embolization for Fibroids

CardioVascular and Interventional Radiology — Thu, 26 Jan 2012 06:55:40 +0100

We report a case of a 43-year-old woman who underwent uterine artery embolization (UAE) for a symptomatic large fibroid uterus and had spontaneous perforation of the transverse colon 3 months after embolisation with near-fatal consequences. We believe this is the first reported case in the literature of this serious complication of UAE. We briefly review the literature on bowel complications after UAE and discuss lessons to be learned regarding patient selection and postprocedure follow-up. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00270-012-0349-5Authors Jyotsna Acharya, Royal Bolton Hospital, Minerva Road, Farnworth, Bolton, Lancashire, BL4 0JR UKKaren Bancroft, Royal Bolton Hospital, Minerva Road, Farnworth, Bolton, Lancashire, BL4 0JR UKJames ...

The shootings in Oslo and Utoya island July 22, 2011: Lessons for the International EMS community

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine — Thu, 26 Jan 2012 05:00:00 +0100

This commentary discusses the recently published emergency medical service response report from the attacks in Norway on July 22, highlighting key factors that affected the prehospital response service. (Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine)

Therapy of lupus nephritis: lessons learned from clinical research and daily care to patients

Arthritis Research and Therapy — Thu, 26 Jan 2012 05:00:00 +0100

No systemic connective tissue disease ever prompted so many randomized clinical trials over the last three decades as lupus nephritis (LN). Yet, renal involvement still significantly impacts the survival and the quality of life of lupus patients and the search for the ideal immunosuppressive regime is far from complete. The purpose of this review is to summarize the major recent achievements in the field. More specifically, the following topics will be discussed: intravenous cyclophosphamide versus mycophenolate mofetil (MMF) for induction, azathioprine versus MMF for maintenance, targeted therapies. Clues for optimal global care will be adressed, such as the need for complete initial evaluation, the importance of patient's education, the unmasking of non-compliance to therapy, the reason ...

The shootings in Oslo and Utøya island July 22, 2011: Lessons for the International EMS community

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine — Thu, 26 Jan 2012 05:00:00 +0100

Cellular transformation by human papillomaviruses: Lessons learned by comparing high- and low-risk viruses.

Virology — Thu, 26 Jan 2012 05:00:00 +0100

Authors: Klingelhutz AJ, Roman A Abstract The oncogenic potential of papillomaviruses (PVs) has been appreciated since the 1930s yet the mechanisms of virally-mediated cellular transformation are still being revealed. Reasons for this include: a) the oncoproteins are multifunctional, b) there is an ever-growing list of cellular interacting proteins, c) more than one cellular protein may bind to a given region of the oncoprotein, and d) there is only limited information on the proteins encoded by the corresponding non-oncogenic PVs. The perspective of this review will be to contrast the activities of the viral E6 and E7 proteins encoded by the oncogenic human PVs (termed high-risk HPVs) to those encoded by their non-oncogenic counterparts (termed low-risk HPVs) in an attempt to sort...

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Beware: Thinking Leads to Doing

Psychology Today Relationships Center — Thu, 26 Jan 2012 01:20:59 +0100

Sports psychologists teach athletes to visualize making a winning basketball free throw or an effective tennis serve before doing the action. That’s because thinking prepares you for doing. When you think about something, the odds zoom upwards that you will do just what your mind was picturing. The lesson: be careful what you think about! read more (Source: Psychology Today Relationships Center)

Lessons About the Heart, of the Heart, and From the Heart: Remembering J. Willis Hurst

Clinical Cardiology — Wed, 25 Jan 2012 05:00:00 +0100

(Source: Clinical Cardiology)

Continuing Bipolar for Beginners: Causes of Bipolar Disorder

About.com Bipolar Disorder — Wed, 25 Jan 2012 05:00:00 +0100

Here's part 2 of Bipolar for Beginners, a series designed to walk you through the basic information about bipolar disorder. Lesson 1, Introducing Bipolar Disorder, started you out with the most basic information: an explanation of what bipolar is along with definitions of terms that are essential to understanding the illness. Lesson 1 also debunks some of the common myths. Lesson 2 covers what's known about the genetic component of mental disorders, theories regarding the relationship between stress and genetic susceptibility, and types of stresses that could bring on a bipolar episode. In addition, this lesson takes a look at the inner workings of nerves in the brain that are thought to affect moods. Finally, there's the story of a court decision legally confirming that bipolar disorder ...

Life Lessons from a Poodle

Psychology Today Parenting Center — Wed, 25 Jan 2012 02:06:20 +0100

It has been said that we live in the information age. Most people have more access to more information–fact, fiction, reality, opinion…–than ever before. Simultaneously we live in an age where the quality of primary and secondary education has deteriorated steadily. More and more people spend more and more time in cyberspace than in reality.read more (Source: Psychology Today Parenting Center)

Caution when applying "lessons" from suresh et Al.

Anesthesia and Analgesia — Tue, 24 Jan 2012 22:54:14 +0100

Caution when applying "lessons" from suresh et Al. Anesth Analg. 2012 Feb;114(2):480 Authors: Cheng A, Mahajan A, Rozner M PMID: 22266702 [PubMed - in process] (Source: Anesthesia and Analgesia)

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Am I worthy? Lesson 1 in Vulnerability

Psychology Today Relationships Center — Tue, 24 Jan 2012 21:49:48 +0100

When you finally allow people to see who you are they may reject you and you can't protect your ego by saying that they didn't really know you. That thought alone terrifies me.read more (Source: Psychology Today Relationships Center)

Nigeria: The Nation and Polio - Lessons From India

AllAfrica News: Health and Medicine — Tue, 24 Jan 2012 11:07:34 +0100

Daily Trust (Abuja)-According to World Health Organization's (WHO) news release titled 'One year polio free in India is a major achievement; the country was once the world's epicentre of polio' on 12 January 2012 -India appears to have interrupted wild poliovirus transmission, completing one year without polio since its last case, in a 2-year-old girl in the state of West Bengal, on 13 January 2011. (Source: AllAfrica News: Health and Medicine)

Connecting Science and Practice in Child and Adolescent Mental Health Services Research

Administration and Policy in Mental Health and Mental Health Services Research — Tue, 24 Jan 2012 07:19:56 +0100

Abstract Collaboration between researchers and stakeholder groups is a potentially powerful mechanism for strengthening the quality of mental health research and for amplifying its public health impact. For stakeholders, collaboration offers opportunities to help shape research questions; participate in data collection and interpretation; and improve local capacity to access and use research findings. For researchers, collaboration can build understanding of what stakeholders want and need from research; enhance capacity to frame research questions and findings in language and metrics of value to stakeholders; and provide opportunities to contribute science-backed knowledge to decision-making processes in real world settings. Key stakeholder groups can include the recipien...

CMF revisited in the 21st century

Annals of Oncology — Tue, 24 Jan 2012 05:00:00 +0100

In conclusion, although we have learned a lot from the use of CMF, many questions are still open and hopefully stimulate our thinking, as clinicians, leading us to find new and more effective ways to treat breast cancer. (Source: Annals of Oncology)

Creating Community Collaboration to Improve the Care of Patients With High Blood Pressure: Lessons From Rochester, New York

The Journal of Clinical Hypertension — Tue, 24 Jan 2012 05:00:00 +0100

This report describes the process to date and hopefully will stimulate conversations about mechanisms to encourage similar collaboration within other communities. (Source: The Journal of Clinical Hypertension)

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Scaling up community mobilisation through women's groups for maternal and neonatal health: experiences from rural Bangladesh

BMC Pregnancy and Childbirth - Latest articles — Tue, 24 Jan 2012 05:00:00 +0100

Conclusions: Examination and documentation of how scaling-up was successfully initiated, led, managed and monitored in rural Bangladesh provide a deeper knowledge base and valuable lessons.Strong operational capabilities and institutional knowledge of the implementing organisation were critical to the success of scale-up. It was possible to increase community engagement with the intervention without financial incentives and without an increase in managerial staff. Monitoring and feedback systems that allow for periodic programme corrections and continued innovation are central to successful scale-up and require programmatic and operational flexibility. (Source: BMC Pregnancy and Childbirth - Latest articles)

Lessons from Disaster At Sea

Psychology Today Depression Center — Mon, 23 Jan 2012 14:59:14 +0100

Since the capsize of the Costa Concordia last week and the news that up to 32 people have lost their lives some commentators have mentioned similarities with the Titanic. To understand the situation it is useful to look for points of similarity to previous incidents.read more (Source: Psychology Today Depression Center)

Lessons in coral reef survival from deep time

ScienceDaily Headlines — Mon, 23 Jan 2012 14:48:48 +0100

Lessons from tens of millions of years ago are pointing to new ways to save and protect today's coral reefs and their myriad of beautiful and many-hued fishes at a time of huge change in the Earth's systems. Today's complex relationship between fishes and corals developed relatively recently in geological terms -- and is a major factor in shielding reef species from extinction, say experts. (Source: ScienceDaily Headlines)

Lessons from the Film ‘Limitless’

CounsellingResource.com News and Features — Mon, 23 Jan 2012 13:10:14 +0100

Although film critics have given Limitless tepid praise, I found this movie to be deeply meaningful as a therapist. Understand Limitless and you understand many of the dreams and nightmares that haunt modern life.Tags: addiction, ADHD, drug abuse, intelligence, medications, motivation, society, therapy (Source: CounsellingResource.com News and Features)

Lessons Learned in Running My Private Medical Practice

Physicians Practice — Mon, 23 Jan 2012 12:00:00 +0100

Two years of running my private practice has taught me a great deal, such as “paperless” is a fantasy. (Source: Physicians Practice)

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Cellular geography of IP3 receptors, STIM and Orai: a lesson from secretory epithelial cells.

Biochemical Society Transactions — Sun, 22 Jan 2012 22:29:40 +0100

Authors: Dingsdale H, Voronina S, Haynes L, Tepikin A, Lur G Abstract Pancreatic acinar cells exhibit a remarkable polarization of Ca2+ release and Ca2+ influx mechanisms. In the present brief review, we discuss the localization of channels responsible for Ca2+ release [mainly IP3 (inositol 1,4,5-trisphosphate) receptors] and proteins responsible for SOCE (store-operated Ca2+ entry). We also place these Ca2+-transporting mechanisms on the map of cellular organelles in pancreatic acinar cells, and discuss the physiological implications of the cellular geography of Ca2+ signalling. Finally, we highlight some unresolved questions stemming from recent observations of co-localization and co-immunoprecipitation of IP3 receptors with Orai channels in the apical (secretory) region of pancr...

Reflecting on Haiti

Thrive, Children's Hospital Boston — Sun, 22 Jan 2012 18:19:41 +0100

By Dennis Rosen, MD Photo: Dennis Rosen This month marks the second anniversary of the January 2010 earthquake that devastated Port au Prince, killing more than a quarter million, injuring over 350,000, and leaving an estimated one million without shelter. Having gone there three times since then with groups from Children’s Hospital Boston to participate in the relief efforts, hardly a day goes by that I am not reminded of what I saw and lived during those weeks. Ranging from the truly horrible to inspiring and uplifting, many of the experiences were unlike any others I had had prior to setting foot in Haiti. The first time I went was in May 2010 with a group that worked at the General Hospital along with Partners in Health. Conditions on the ground were utterly chaotic, and the dis...

Can A Middle-Aged Neophyte Make It to Carnegie Hall?

Scientific American - Official RSS Feed — Sat, 21 Jan 2012 12:00:00 +0100

Gary Marcus suffers from what a friend jokingly describes as congenital arrhythmia--the inability, despite many hours of his youth spent practicing and taking lessons, to learn to play a musical instrument. A few years ago Marcus, a cognitive psychologist at New York University, decided at 38 to make one last try when he took up guitar. No surprise: He did not succeed in becoming the next Jimi Hendrix, but managed to acquire a modicum of skill--and went on to describe his experience in Guitar Zero: The New Musician and the Science of Learning . [More] (Source: Scientific American - Official RSS Feed)

Correction

Journal of the American College of Surgeons — Sat, 21 Jan 2012 10:57:32 +0100

In the article, “Current Trends in Regional Therapy for Melanoma: Lessons Learned from 225 Regional Chemotherapy Treatments between 1995 and 2010 at a Single Institution,” by Raymond AK, Beasley GM, Broadwater G, et al, which appeared in the August 2011 issue of the Journal of the American College of Surgeons, volume 213, pages 306–318, the authors incorrectly labeled in this article. The correct figure and legend are: (Source: Journal of the American College of Surgeons)

Keen to drive science into medicine? Four lessons from an innovation conference.

Forbes.com Healthcare News — Sat, 21 Jan 2012 07:46:57 +0100

I’ve just returned from participating in an engaging and highly interactive translational research innovation symposium at Duke University this past Thursday put together by Dr. David Epstein at the Duke Eye Center and Chancellor Victor Dzau, and featuring both University faculty and invited external speakers. Four key themes emerged: (Source: Forbes.com Healthcare News)

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Costs of Care Contest Winners Offer Lessons Learned on Providing High...

PRWeb: Medical Pharmaceuticals — Sat, 21 Jan 2012 05:56:11 +0100

Costs of Care, a nonprofit that helps caregivers deflate medical bills and provide high value care, has chosen four winners in its second annual national healthcare essay contest. These stories from...(PRWeb January 18, 2012)Read the full story at http://www.prweb.com/releases/2012/1/prweb9111769.htm (Source: PRWeb: Medical Pharmaceuticals)

Commentary: Enforcement Works

Annals of Emergency Medicine — Fri, 20 Jan 2012 19:16:32 +0100

[Ann Emerg Med. 2012;142-144.] Enforcement works. That is the lesson of NHTSA's Traffic Safety Facts Research Note “High Visibility Enforcement Demonstration Programs in Connecticut and New York Reduce Hand-Held Phone Use.” And publicly announced, visible, open enforcement is even better. The authors reviewed a program that demonstrated significant changes in driver behavior according to a funded, well-publicized enforcement campaign. (Source: Annals of Emergency Medicine)

Vital signs: A lesson in fear

BMA daily feed — Fri, 20 Jan 2012 11:14:00 +0100

‘When doctors were battling to save my wife’s life, I suddenly remembered Barry’ (Source: BMA daily feed)

Influence of the quality implementation of a physical education curriculum on the physical development and physical fitness of children

BMC Public Health - Latest articles — Fri, 20 Jan 2012 05:00:00 +0100

Conclusions: Specialist PE teachers were more successful than generalist teachers in achieving greater improvement of children's physical fitness, but no differences were observed in physical development of quasi-test and quasi-control group. (Source: BMC Public Health - Latest articles)

Clinical characteristics of massive air embolism complicating left atrial ablation of atrial fibrillation: lessons from five cases

Europace — Fri, 20 Jan 2012 05:00:00 +0100

Conclusion Serious air embolism can occur in patients with long apnoea under sedation during AF ablation with the use of long sheaths. Supportive therapy and air aspiration were effective in resolving the complication. A sedative that causes less respiratory depression and the timing of the saline flush were important for preventing air embolism. (Source: Europace)

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Crosstalk between Inflammation and Coagulation: The Lessons of Sepsis.

Current Vascular Pharmacology — Fri, 20 Jan 2012 05:00:00 +0100

Authors: van der Poll T, Levi M Abstract Sepsis results in the concurrent activation of inflammatory and procoagulant pathways. Bacterial products and proinflammatory cytokines trigger the coagulation system primarily via induction of tissue factor. During sepsis, activation of coagulation is accompanied by impaired function of major anticoagulant mechanisms, including antithrombin, the protein C system and fibrinolysis. Protease activated receptors (PARs) form the molecular connection between coagulation and inflammation, and especially PAR1 seems to play an eminent role in sepsis pathogenesis. Activated protein C (APC) can cleave PAR1 when associated with either the endothelial protein C receptor (EPCR) or CD11b/CD18, resulting in broad cytoprotective effects mediated by sphingos...

Louisiana Man Caught Burning Asbestos Shingles for 2nd Time Slapped with Fine

Asbestos and Mesothelioma News — Thu, 19 Jan 2012 20:51:28 +0100

After failing to learn his lesson the first time, a Louisiana man is sentenced by District Court Judge for violating strict laws against burning asbestos shingles. (Source: Asbestos and Mesothelioma News)

Telehealth failure a cautionary tale for U.S.

ICMCC: The International Council on Medical and Care Compunetics — Thu, 19 Jan 2012 15:45:21 +0100

Source: Sara Jackson, FierceHealthIT Content: “Getting docs engaged and on-board with telehealth may take more than education. It may take cold, hard cash. That’s the object lesson this week from a story about one segment of England’s burgeoning telehealth/remote patient monitoring program. Not getting physician buy-in has forced one primary care trust–the local care coordinating agency [...] (Source: ICMCC: The International Council on Medical and Care Compunetics)

School health lessons 'made our son anorexic after it made him paranoid about junk food'

the Mail online | Health — Thu, 19 Jan 2012 13:09:51 +0100

Mr and Mrs Fieldsend, from Hull, East Yorkshire, claim that James's problem started when he was seven, after he was taught about healthy eating at school. (Source: the Mail online | Health)

Airway management of recovered pediatric patients with severe head and neck burns: a review

Pediatric Anesthesia — Thu, 19 Jan 2012 05:00:00 +0100

This article aims to provide a comprehensive review of airway management in such patients, focusing on challenges encountered during mask ventilation and tracheal intubation, as well as the role of surgical release of neck contractures to facilitate tracheal intubation. Lessons learned from all reported cases identified in a thorough literature search are incorporated into this review. (Source: Pediatric Anesthesia)

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Global news highlights

Injury Prevention — Thu, 19 Jan 2012 05:00:00 +0100

Indians still waiting for anticollision devices on trains Twelve years ago, a railway in India developed an anticollision device (ACD) to help prevent train crashes. These devices have still not been installed in all trains in spite of successful trials. An ACD is designed to prevent head-on, side and rear-end collisions. It is believed that ‘more than 50% of railway collisions are caused by driver lapses’ who require this technical aid to preventing collisions. In the Railway Budget 2010, the then railway minister Mamata Banerjee announced these measures. ‘To make railways safer, anti-collision devices (ACD) and Train Protection Warning Systems (TPWS) are ... to be installed. Also, automatic fire and smoke detection systems were to be placed in long-distance trains.&rsqu...

Lessons from the past

Injury Prevention — Thu, 19 Jan 2012 05:00:00 +0100

The National Center for Health Statistics (NCHS) recently announced that poisoning had passed motor vehicle (MV) crashes as the leading cause of injury death in the USA in 2008.1 The NCHS also noted that nearly 90% of poisoning deaths were due to drugs, which have driven the overall poisoning mortality increase since at least 1980. Much of the increase in drug poisoning mortality was due to prescription drugs, especially opioid painkillers. Similar trends related to prescription opioids have been noted in other developed countries.2 3 Preliminary mortality data from 2009 suggest an additional large decline in MV crash deaths,4 5 while emergency department data suggest a continued increase in prescription drug overdoses in 2009.6 It is likely that drug poisoning alone now causes more deaths...

Finding and fixing diagnosis errors: can triggers help?

Quality and Safety in Health Care — Thu, 19 Jan 2012 05:00:00 +0100

Imagine conferring with your clinician colleagues and being handed a plateful of all of your missed and delayed diagnoses. But, imagine further that, rather than a nightmare of ghosts returning to haunt you in the form of malpractice claims, sanctions by regulatory boards, insurers pouncing on needless expenditures or hordes (yes, there would be large numbers) of angry finger-pointing patients and families, the experience would instead bring a dream of supportive feedback and learning. Imagine the ways such an idealised non-threatening consultation and conference might be designed to minimise defensiveness and maximise introspection, learn lessons, and rethink habits and standard practices. Rather than prompting incredulous exclamations of "you missed that?!" or "what were you thinking?!",...

Turning Toward Dissonance: Lessons From Art, Music, and Literature

Journal of Pain and Symptom Management — Thu, 19 Jan 2012 03:24:50 +0100

Abstract: Conflict and chaos are prevalent in health care, and perhaps especially in palliative care. Typically, our point of entry into our patients' lives is often at the moment of conflict, discord, or intense suffering. Despite this, little in our formal training as clinicians teaches us how to be present for this suffering. Much has been written about the process of communication with regard to giving bad news, handling family meeting conflicts, and negotiating shifting goals of care, but little has been addressed about how to train the clinician to be present with the dissonance and suffering. In this paper, we explore how music, art, and literature teach us how to stay in moments of tension. In turn, lessons on how to learn to lean into the dissonance of many palliative care encount...

Culture Eats Strategy for Breakfast: Lessons Learned From Implementing a Palliative Care Service in a Nursing Home (300)

Journal of Pain and Symptom Management — Thu, 19 Jan 2012 03:24:50 +0100

Identify four specific challenges inherent in implementing a palliative care service in a nursing home setting. (Source: Journal of Pain and Symptom Management)

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Can Delirium Be Prevented in Palliative Care? Incorporating the Lessons of Geriatrics, Oncology, and Surgery (505)

Journal of Pain and Symptom Management — Thu, 19 Jan 2012 03:24:50 +0100

Discuss the geriatric approach of risk factor identification and modification in order to prevent delirium. (Source: Journal of Pain and Symptom Management)

Practitioners' Offices: Lessons from the Past

Psychology Today Work Center — Thu, 19 Jan 2012 01:28:09 +0100

When we look back to the state of medical practice at the beginning of the 20th century, there's a lot of good advice for psychologists today, especially about where offices should be located and how they should look.read more (Source: Psychology Today Work Center)

Interior to Establish Science Panel for Environmental Crises

Public Policy Reports — Wed, 18 Jan 2012 20:12:42 +0100

Secretary of the Interior Ken Salazar has ordered the creation of a new group of scientific advisors who will help the department to plan for and address environmental emergencies. The Strategic Science Group will help Interior plan for environmental crises by providing science-based assessments of probable environmental crises, such as severe drought, wildfires, or an oil spill. When an emergency does occur, the group will rapidly assemble teams of scientists from government, academia, non-governmental organizations, and the private sector to assist with Interior’s response. The group will be co-lead by Gary Machlis, a science adviser for the National Park Service, and David Applegate, associate director for natural hazards at the U.S. Geological Survey. “Using the important...

'Let Science Guide Us' on Prostate Screening'Let Science Guide Us' on Prostate Screening

Medscape Today Headlines — Wed, 18 Jan 2012 17:18:56 +0100

Dr. Gerald Chodak encourages clinicians to embrace the lessons offered thus far from the PLCO trial. Medscape Urology (Source: Medscape Today Headlines)

Ian Stewart's top 10 popular maths books

Guardian Unlimited Science — Wed, 18 Jan 2012 12:45:57 +0100

From biography to magic to authentically world-changing texts, the much-acclaimed author chooses the best guides to 'the Cinderella science' for general readersIan Stewart is an Emeritus Professor of Mathematics at Warwick University and a Fellow of the Royal Society. He has written over 80 books, mainly popular mathematics, and has won three gold medals for his work on the public understanding of science. In collaboration with Terry Pratchett and Jack Cohen he wrote the Science of Discworld series. His new book, 17 Equations That Changed the World, is published by Profile.Buy 17 Equations That Changed the World from the Guardian bookshop"'Popular mathematics' may sound like a contradiction in terms. That's what makes the genre so important: we have to change that perception. Mathematics i...

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Kings’ School, Winchester: 11 classes in 1 month!!

Support for International Change : HIV AIDS — Wed, 18 Jan 2012 08:44:23 +0100

During November, HIVE Southampton welcomed the challenge of teaching a grand total of 11 Science classes at Kings School in Winchester, over a two-week period. Pupils were encouraged to think independently in deducing the fundamental differences between bacteria and viruses. They eagerly took to applying their knowledge through our teaching tool “Who Wants to be a Millionaire,” learning about HIV transmission and methods of prevention. Through the transmission practical, pupils appreciated the asymptomatic nature of initial HIV infection, thus learning the importance of screening in developing countries, to prevent rapid population dissemination. Many thanks to the pupils for offering a diverse and intuitive array of questions, and Kings School teachers for their inv...

A review on gastric diverticulum

World Journal of Emergency Surgery — Wed, 18 Jan 2012 05:00:00 +0100

The gastric fundal diverticulae are rare. They can present with variable symptoms. We are enclosing a literature review on gastric fundal diverticulum. Lessons have emerged which may help in the management of this rare condition in future. (Source: World Journal of Emergency Surgery)

Public health: Biodefence built on teamwork

Nature — Wed, 18 Jan 2012 05:00:00 +0100

Nature 481, 7381 (2012). doi:10.1038/481261a Author: John Grabenstein The golden era of US vaccine research holds beneficial lessons for today, finds John Grabenstein. (Source: Nature)

CCG case studies: patient and public engagement (PPE)

NHS Networks — Wed, 18 Jan 2012 05:00:00 +0100

The aim was for each emerging CCG and primary care trust to widen community participation. In a new series of PPE case studies, four of these CCGs are now sharing their experiences and lessons learned. Two focus on social media and technology, and two look at running a citizens’ jury. (Source: NHS Networks)

Lessons from a mathematical hypothesis: modification of the endoventricular circular patch plasty [LETTERS TO THE EDITOR]

European Journal of Cardio-Thoracic Surgery — Wed, 18 Jan 2012 05:00:00 +0100

(Source: European Journal of Cardio-Thoracic Surgery)

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Acoustic brainstem implant in a post-meningitis deafened child—Lessons learned

International Journal of Pediatric Otorhinolaryngology — Tue, 17 Jan 2012 21:16:10 +0100

We report a case of a deafened child with advanced labyrinthitis ossificans resulting from meningo-encephalitis. She received a cochlear implant in the right ear, following a drill-out procedure. Post-implant hearing outcomes were satisfactory initially, but deteriorated over time as a result of partial electrode migration. The child subsequently received a left auditory brainstem implantation with improvement of hearing outcomes. Post-operatively, a sub-dural hematoma developed not on the side of the operation but on the opposite side. Simultaneous use of the cochlear implant on one side and the acoustic brainstem on the other, aggravated the non-auditory side effects of the ABI and compromised its potential for optimal hearing results. (Source: International Journal of Pediatric Otorhino...

Mystery bird: Striated heron, Butorides striata | GrrlScientist

Guardian Unlimited Science — Tue, 17 Jan 2012 17:33:00 +0100

Even though it's not migratory, this Malaysian mystery bird species pops up in tropical wetlands around the worldStriated heron, Butorides striata (synonym, Butorides striatus; protonym, Ardea striata), Linnaeus, 1758, also known as the mangrove heron or mangrove bittern, as the little mangrove heron, the little heron, as the eastern green heron, the little green heron or as the green-backed heron, or as Anthony's green heron or as Frazar's green heron, or, colloquially, as the fly-up-the-creek, as the Shite-poke, shitpoke, or simply as the poke, photographed at Mabul island, south-eastern coast of Sabah (Malaysia). Image: Konstans Wells, 28 December 2011 (with permission) [velociraptorize].Nikon D90, 105 mm AF-S Nikkor lens 18-105 mm ED Question: This Malaysian mystery bird species is qui...

The Uses of the Past: Why Science Writers Should Care About the History of Science And Why Scientists Should Too

Scientific American - Official RSS Feed — Tue, 17 Jan 2012 11:07:00 +0100

"The Anatomy Lesson of Homo sylvestris" by Nathaniel Gold Whether we are exploring our family genealogy or the genetic tree of our primate ancestors, all of us have a common yearning to know from whence we came. Origin stories captivate our imagination and offer a narrative structure for better understanding where we are today. The reality is that a knowledge of the history of science can both challenge our present and inspire the future. [More] (Source: Scientific American - Official RSS Feed)

Superbugs & Superdrugs â�¨- A Focus On Antibacterials, 5-6 March 2012, Copthorne Tara Hotel, London

Health News from Medical News Today — Tue, 17 Jan 2012 08:00:00 +0100

â�¨SMi present Europe's leading antibacterial event; Superbugs & Superdrugs. This well established event, now in its 14th year, will consist of a variety of different case study focused presentations featuring real life success stories and lessons learnt from project failures enabling attendees to learn from and discuss with key industry professional on challenges facing this rapidly-evolving field... (Source: Health News from Medical News Today)

Superbugs & Superdrugs - A Focus On Antibacterials, 5-6 March 2012, Copthorne Tara Hotel, London

Health News from Medical News Today — Tue, 17 Jan 2012 08:00:00 +0100

SMi present Europe's leading antibacterial event; Superbugs & Superdrugs. This well established event, now in its 14th year, will consist of a variety of different case study focused presentations featuring real life success stories and lessons learnt from project failures enabling attendees to learn from and discuss with key industry professional on challenges facing this rapidly-evolving field... (Source: Health News from Medical News Today)

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Lessons in Elder Care [A Piece of My Mind]

JAMA — Tue, 17 Jan 2012 05:00:00 +0100

(Source: JAMA)

Predicting cross‐reactive immunological material (CRIM) status in Pompe disease using GAA mutations: Lessons learned from 10 years of clinical laboratory testing experience

American Journal of Medical Genetics Part C: Seminars in Medical Genetics — Tue, 17 Jan 2012 05:00:00 +0100

AbstractEnzyme replacement therapy (ERT) for Pompe disease using recombinant acid alpha‐glucosidase (rhGAA) has resulted in increased survival although the clinical response is variable. Cross‐reactive immunological material (CRIM)‐negative status has been recognized as a poor prognostic factor. CRIM‐negative patients make no GAA protein and develop sustained high antibody titers to ERT that render the treatment ineffective. Antibody titers are generally low for the majority of CRIM‐positive patients and there is typically a better clinical outcome. Because immunomodulation has been found to be most effective in CRIM‐negative patients prior to, or shortly after, initiation of ERT, knowledge of CRIM status is important before ERT is begun. We have analyzed 243 patients with infa...

Impulse control and criminal responsibility: Lessons from neuroscience.

International Journal of Law and Psychiatry — Tue, 17 Jan 2012 05:00:00 +0100

Authors: Penney S Abstract Almost all of the world's legal systems recognize the "M'Naghten" exception to criminal responsibility: the inability to appreciate the wrongfulness of action. This exception rests on the assumption that punishment is morally justified only if the defendant was able to choose whether to do wrong. Jurists and jurisdictions differ, however, on whether to extend M'Naghten's logic to cases where the defendant understood the wrongfulness of an act but was incapable of resisting an impulse to commit it. In this article I ask whether contemporary neuroscience can help lawmakers to decide whether to adopt or retain this defense, known variously as the "irresistible impulse" defense or the "control" or "volitional" test for insanity. More specifically, I ask first...

British tough guy gives funny CPR lesson

USATODAY.com Health — Mon, 16 Jan 2012 20:24:00 +0100

Whether you're a Brit or an American, tough or funny, new CPR viral videos show 'hard' and 'fast' technique. (Source: USATODAY.com Health)

Scott's lost Antarctica photographs bought for the nation

Guardian Unlimited Science — Mon, 16 Jan 2012 18:17:00 +0100

Pictures acquired with help of Heritage Lottery Fund grant in time for centenary of ill-fated journeyThe last photographs taken by Captain Robert Scott, lost for most of the 20th century, have been bought for the nation in time for the centenary of his doomed expedition to reach the south pole on 17 January 1912.The anniversary is being marked by many institutions, including:• The Natural History Museum in London, where an exhibition on the venture featuring a recreation of Scott's hut which survives in Antarctica, opens on Friday.• A conference at the Scott Polar Research Institute in Cambridge, where there is an exhibition with many surviving artefacts.• The Historic Dockyard at Portsmouth, where a single white rose will be laid at the foot of his statue – sculpted by his widow, ...

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Kissing Balloon or Sequential Dilation of the Side Branch and Main Vessel for Provisional Stenting of Bifurcations: Lessons From Micro-Computed Tomography and Computational Simulations

Journal of the American College of Cardiology: Cardiovascular Interventions — Mon, 16 Jan 2012 05:00:00 +0100

Conclusions Sequential 2-step post-dilation of the SB and MV may offer a simpler and more efficient alternative to final KB technique for provisional stenting of bifurcations. (Source: Journal of the American College of Cardiology: Cardiovascular Interventions)

Lessons From the Learning Curve

Journal of the American College of Cardiology: Cardiovascular Interventions — Mon, 16 Jan 2012 05:00:00 +0100

(Source: Journal of the American College of Cardiology: Cardiovascular Interventions)

Lessons learned from 20 years of newborn screening for cystic fibrosis.

Med J Aust — Mon, 16 Jan 2012 05:00:00 +0100

CONCLUSION: Most babies with CF without meconium ileus, a family history or antenatal diagnosis are detected by newborn screening. Despite improved sensitivity with the 12-mutation analysis, most infants detected would have been diagnosed using the IRT/p.F508del protocol. PMID: 22256939 [PubMed - in process] (Source: Med J Aust)

Can Alberta's primary care networks provide any lessons for Medicare Locals?

Med J Aust — Mon, 16 Jan 2012 05:00:00 +0100

Authors: Suchowersky A, Suchowersky O, Duckett SJ Abstract Australia's Medicare Locals are in a formative period, and any comparison so far has focused on the United Kingdom. PMID: 22256923 [PubMed - in process] (Source: Med J Aust)

Wildlife Strike Risk Assessment in Several Italian Airports: Lessons from BRI and a New Methodology Implementation. - Soldatini C, Albores-Barajas YV, Lovato T, Andreon A, Torricelli P, Montemaggiori A, Corsa C, Georgalas V.

SafetyLit: All (Unduplicated) — Sat, 14 Jan 2012 23:37:58 +0100

The presence of wildlife in airport areas poses substantial hazards to aviation. Wildlife aircraft collisions (hereafter wildlife strikes) cause losses in terms of human lives and direct monetary losses for the aviation industry. In recent years, wildlife ... (Source: SafetyLit: All (Unduplicated))

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Perspectives Always the Lessons

Military Medicine — Sat, 14 Jan 2012 23:37:51 +0100

(Source: Military Medicine)

Patient selection for bedside teaching: inclusion and exclusion criteria used by teachers

Medical Education — Sat, 14 Jan 2012 22:54:53 +0100

Conclusions Patient selection for bedside teaching is based on several criteria. Non‐representative patient selection may narrow the learning experiences of medical students. Curriculum planners need to be aware that specific aspects of medical care may be neglected as a result of the exclusion of some patients. Teacher training and additional teaching formats should be provided to ensure that these are covered. (Source: Medical Education)

Lessons from Tebow and Elway

Psychology Today Parenting Center — Sat, 14 Jan 2012 16:42:45 +0100

Maybe football is more than "just a game." Maybe football reminds us about what is best about American culture.read more (Source: Psychology Today Parenting Center)

Lessons we can learn from gene expression patterns in rotator cuff tears and tendinopathies

Journal of Shoulder and Elbow Surgery — Sat, 14 Jan 2012 14:39:38 +0100

Persistently high failure rates that are reported after rotator cuff repairs have encouraged greater understanding of the pathophysiology that underlies rotator cuff tears. Biologic changes that contribute to the pathogenesis of rotator cuff tears and tendinopathies, as well as adaptation after these changes, have been well described. A subset of patients with a genetic predisposition to early onset of rotator cuff tears and earlier symptom and disease progression have been identified. Many biologic changes occurring at the gene level have been identified. Pathways that are believed to contribute to rotator cuff tendinopathies include extracellular matrix remodeling, angiogenesis, changes in metabolism, apoptosis, and stress-related genes. Metaplasia of rotator cuff cells is contributed to...

Report: Pharmacy students benefit by early introduction to MTM curricula

Drug Topics - Pharmacy News — Sat, 14 Jan 2012 05:00:00 +0100

Two pharmacy organizations issued a report aimed at helping colleges and schools of pharmacy develop medication therapy management curricula. The study also emphasized the importance of students learning these lessons early. (Source: Drug Topics - Pharmacy News)

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[Editorial] Silicone breast implants: lessons from the USA

LANCET — Sat, 14 Jan 2012 05:00:00 +0100

The scandal engulfing the use of silicone-gel breast implants in the UK and across Europe might seem an isolated example of regulatory failure for an uncommon device. But breast implants are widely used, the cosmetic industry is growing, and there are valuable lessons to learn from countries that have experienced their own regulatory crises. The USA is one such country. Last year alone, silicone-gel implants were used in almost 150 000 American women for breast augmentation and in 46 000 women for breast reconstruction. (Source: LANCET)

[Viewpoint] What are the lessons from the USA for clinical commissioning groups in the English National Health Service?

LANCET — Sat, 14 Jan 2012 05:00:00 +0100

The UK coalition Government's plans to make groups of general practices responsible for commissioning health services have attracted much attention. Investigation of the experiences of other countries in which doctors control budgets could help the UK to understand how these plans might work. We visited the USA in March 2011 to learn how medical groups manage the budgets that they negotiate with health insurers and how they work with hospitals to control costs and improve outcomes. Our report describes what we learnt and identifies several lessons for the National Health Service (NHS), as the government's plans to establish clinical commissioning groups are taken forward. (Source: LANCET)

Resource management in ant colonies may have lessons for politicians and economists

ScienceDaily Headlines — Sat, 14 Jan 2012 01:56:56 +0100

Political and economic theorists could learn lessons from studying how an ant colony allocates food resources, according to a new article. (Source: ScienceDaily Headlines)

The science behind memory glitches

Guardian Unlimited Science — Sat, 14 Jan 2012 00:22:00 +0100

What is deja vu? And why do we sometimes enter a room only to forget why we're there? Christian Jarrett explains the science behind common memory misfitsDeja vuEach lived moment usually feels unique. But about two-thirds of us occasionally experience the fleeting sensation that life is on repeat. It's as if we've been in exactly the same place having exactly the same experience before, even though we know that's an impossibility.Known as deja vu (literally "already seen"), an early explanation was that the feeling arises from a delayed signal arriving from one of the eyes after a scene has already been processed by the brain. However, that idea was seemingly refuted by the case of a blind man who experienced deja vu.Modern theories focus on the memory process of familiarity, as distinct ...

Investor: Health startups, forget about employers

mobihealthnews — Fri, 13 Jan 2012 17:46:18 +0100

Skip Fleshman, a Managing Partner at Asset Management Ventures, shared a few tips for those mobile health startups looking to become more that just “one-trick pony” developers of successful apps. In order to capitalize on their real potential and become a long-term, viable business, Fleshman has a few lessons learned to share based on his firm’s [...] (Source: mobihealthnews)

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A State-Wide Partnership to Promote Safe and Supportive Schools: The PBIS Maryland Initiative

Administration and Policy in Mental Health and Mental Health Services Research — Fri, 13 Jan 2012 16:51:18 +0100

We describe some lessons learned from the partnership and identify potential areas for future research on the prevention partnership model. We conclude with a discussion of the implications for both researchers and community partners engaged in translational research in school settings. Content Type Journal ArticleCategory Original PaperPages 1-13DOI 10.1007/s10488-011-0384-6Authors Catherine P. Bradshaw, Department of Mental Health, Johns Hopkins Center for the Prevention of Youth Violence, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USAElise T. Pas, Department of Mental Health, Johns Hopkins Center for the Prevention of Youth Violence, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USAJerry ...

Lessons In Cleaning House

WebMD Health — Fri, 13 Jan 2012 11:39:29 +0100

Quick tips that encourage your child to help with cleaning the house (Source: WebMD Health)

How hospital leaders implemented a safe surgery protocol in Australian hospitals

International Journal for Quality in Health Care — Fri, 13 Jan 2012 05:00:00 +0100

Conclusions A multiplex problem requires graduated and multiplex regulation. Hospital leaders proved to be responsive regulators in applying both multiple supports and sanctions that improved compliance over 3 years. These experiences with protocol implementation illustrate the multifaceted challenge of health sector regulation and offer lessons for embedding future patient safety solutions. (Source: International Journal for Quality in Health Care)

Process analysis to reduce MRI access time at a German University Hospital

International Journal for Quality in Health Care — Fri, 13 Jan 2012 05:00:00 +0100

Quality problem or issue Long access times for magnetic resonance imaging (MRI) can negatively impact the quality of care provided to patients. We investigated improving access by reducing MRI processing time. Initial assessment Data were collected for scans (n= 360) performed over 3 weeks (April–May 2008) at the University Hospital of Mannheim, Germany. Average access time, excluding emergencies, was 44 (±44) days for outpatients and 3 (±5) days for inpatients. Factors influencing total MRI processing time were identified using multivariate linear regression. In addition to region scanned, the total MRI processing time was significantly related to performing multiple scans (β = 33.57, P< 0.01), using oral contrast media (β = 13.58, P< 0.01), placing an...

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Reversal of diabetic nephropathy: lessons from pancreas transplantation.

Journal of Nephrology — Fri, 13 Jan 2012 05:00:00 +0100

We report that diabetic glomerulopathy lesions, unchanged at 5 years post pancreas transplantation, significantly improved after 10 years, with complete normalization of glomerular structure in most patients. Thus this study demonstrates that the lesions of diabetic nephropathy are reversed by long-term normoglycemia and that the human kidney has the potential in humans to obtain a substantial architectural remodeling of the glomerular and tubular structures toward healing. PMID: 22241641 [PubMed - as supplied by publisher] (Source: Journal of Nephrology)

Post-Disaster Recovery: Lessons from the 2010 Haiti earthquake

Scientific American - Official RSS Feed — Thu, 12 Jan 2012 19:00:00 +0100

November 1, 1755 the city of Lisbon was almost completely destroyed by an earthquake followed by a tsunami, estimated 30.000-100.000 people died. For the first time in history a kind of crisis management was organized to deal with the aftermath of this disaster. King Joseph I commissioned the peer and permanent secretary Sebastian Jose Carvalho e Melo (1699-1782, rewarded later by the king for his service and declared Marques de Pombal) to supervise the rescue efforts for the injured, the disposal of the corpses and the rubble and the reconstruction of the city. Asked what to do, Melo responded:“ Bury the dead and heal the living. “ [More] (Source: Scientific American - Official RSS Feed)

1. The physiology of the brainstem respiratory centres: Lessons from a concurrent multithreaded computational model of Rett syndrome

Clinical Neurophysiology — Thu, 12 Jan 2012 11:11:57 +0100

Background: The brain is primarily a massively parallel computer and the brainstem is no exception. Doubtless of vital importance to life, the brainstem centres controlling respiration continue to evade precise identification. Rett syndrome (RTT) is an interesting neurodevelopmental disorder that produces characteristic neurological and behavioural features. Clinical features include autistic traits, loss of purposeful hand movements, stereotyped hand movements and life threatening respiratory rhythm disturbances. The respiratory rhythm abnormalities of RTT include hyperventilation, breath holding, apneustic breathing, etc. (Source: Clinical Neurophysiology)

Report: Pharmacy students benefit by early introduction to MTM curricula

Drug Topics - Top News — Thu, 12 Jan 2012 05:00:00 +0100

Mobile Medical Education (MoMEd) - how mobile information resources contribute to learning for undergraduate clinical students: a mixed methods study.

BMC Medical Education — Thu, 12 Jan 2012 05:00:00 +0100

Conclusions: This is the first study to describe the learning ecology and pedagogic basis behind the use of mobile learning technologies in a large cohort of undergraduate medical students in the clinical environment. We have developed a model for mobile learning in the clinical setting that shows how different theories contribute to its use taking into account positive and negative contextual factors.The lessons from this study are transferable internationally, to other health care professions and to the development of similar initiatives with newer technology such as smartphones or tablet computers. (Source: BMC Medical Education)

'Many voices, one song': a model for an oral health programme as a first step in establishing a health promoting school.

Rural Remote Health — Thu, 12 Jan 2012 05:00:00 +0100

Authors: Macnab A, Kasangaki A Abstract Four health promoting (HP) schools were established in rural communities in Uganda by a joint Ugandan/Canadian university team. The model was based on a successful Canadian health promotion initiative designed to address poor oral health in Aboriginal children in rural and remote communities. Careful situation analysis, orientation of partner schools and collaborative development of educational materials and evaluation methodology preceded implementation. The intervention had three elements: inclusion of health topics by teachers in regular classroom activities; health education delivered by the university team to reinforce key educational concepts; and daily in-school tooth brushing to develop healthy practices. All children entering Grade 1...

Non-attendance at counselling therapy in cocaine-using methadone-maintained patients: lessons learnt from an abandoned randomised controlled trial

Irish Journal of Medical Science — Wed, 11 Jan 2012 17:55:41 +0100

Conclusions Selecting opiate-dependent methadone-maintained cocaine abusers on the basis of their urine toxicology and offering them counselling as a way of reducing their harmful drug use did not prove efficacious. Attempting to address cocaine misuse within this cohort may need a more stepped approach including brief interventions, such as motivational interviewing, or other enhancers of motivation before we can test the effectiveness of CBCS in this population. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s11845-011-0803-4Authors C. Darker, Department of Public Health and Primary Care, Trinity College Centre for Health Sciences, Adelaide and Meath Hospital Dublin, Incorporating the National Children’s Hospital, Tallaght, Dublin 24,...

Are You Producing a Picky Eater?

Psychology Today Food and Diet Center — Wed, 11 Jan 2012 14:07:12 +0100

The gap between the lessons parents think they are teaching and the lesson their kids are actually learning is where eating problems are born.read more (Source: Psychology Today Food and Diet Center)