MedWorm: New York University

People with easy-to-pronounce names are favored at work and in personal life

EurekAlert! - Social and Behavioral Science — Wed, 08 Feb 2012 05:00:00 +0100

(University of Melbourne) Having a simple, easy-to-pronounce name is more likely to win you friends and favor in the workplace, a study by Dr. Simon Laham at the University of Melbourne and Dr. Adam Alter at New York University Stern School of Business, has found. (Source: EurekAlert! - Social and Behavioral Science)

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Obstacles no barrier to higher speeds for worms, NYU researchers find

EurekAlert! - Medicine and Health — Wed, 08 Feb 2012 05:00:00 +0100

(New York University) Obstacles in an organism's path can help it to move faster, not slower, researchers from New York University's Courant Institute of Mathematical Sciences have found through a series of experiments and computer simulations. Their findings have implications for a better understanding of basic locomotion strategies found in biology, and the survival and propagation of the parasite that causes malaria. (Source: EurekAlert! - Medicine and Health)

Positive parenting during early childhood may prevent obesity

EurekAlert! - Social and Behavioral Science — Mon, 06 Feb 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Programs that support parents during their child's early years hold promise for obesity prevention, according to a new study in the online Feb. 6 issue of Pediatrics. (Source: EurekAlert! - Social and Behavioral Science)

NYU Langone orthopaedic experts present research, clinical advances at AAOS meeting

EurekAlert! - Social and Behavioral Science — Mon, 06 Feb 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Experts from the Department of Orthopaedic Surgery at NYU Langone Medical Center will present their latest research and clinical findings on diseases of the muscle, tendon, bone and joint at the annual meeting of the American Academy of Orthopaedic Surgeons, Feb. 7-11 in San Francisco, California. (Source: EurekAlert! - Social and Behavioral Science)

The intracarotid amobarbital procedure: When is it worth repeating?

Epilepsia — Mon, 06 Feb 2012 05:00:00 +0100

SummaryPurpose: Despite the reported diagnostic value of the intracarotid amobarbital procedure (IAP) or “Wada test” for determining hemispheric lateralization and memory functioning, it has never undergone formal reliability testing because a prospective test–retest study design is neither feasible nor ethical. However, some patients require repeat testing for clinical purposes, a circumstance that allows for exploration of issues related to reliability. The current investigation sought to: (1) evaluate the frequency of and reasons for repeated IAPs and (2) describe the test–retest reliability of repeated IAPs in a large tertiary epilepsy center.Methods: A 10‐year review (2001–2011) of the New York University Langone Medical Center Comprehensive Epilepsy Center patient r...

Baseline NT-proBNP and biomarkers of inflammation and necrosis in patients with ST-segment elevation myocardial infarction: insights from the APEX-AMI trial

Journal of Thrombosis and Thrombolysis — Fri, 03 Feb 2012 17:52:05 +0100

Abstract Coronary plaque rupture is associated with a systemic inflammatory response. The relationship between baseline N-terminal pro B-type natriuretic peptide (NT-proBNP), a prognostic marker in patients with acute coronary syndromes, and systemic inflammatory mediators in patients with ST-segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (PCI) is not well described. Of 5,745 STEMI patients treated with primary PCI in the APEX-AMI trial, we evaluated the relationship between baseline NT-proBNP levels and baseline levels of inflammatory markers and markers of myonecrosis in a subset of 772 who were enrolled in a biomarker substudy. Spearman correlations (r s) were calculated between baseline NT-proBNP levels and a pan...

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A new screening method for prostate cancer

EurekAlert! - Medicine and Health — Thu, 02 Feb 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) A new study by NYU Langone Medical Center and Northwestern University Feinberg School of Medicine shows novel PSA velocity risk count testing may provide a more effective way for physicians to screen men for clinically significant prostate cancer. The new study, published online by the British Journal of Urology International, shows the benefits of tracking a man's PSA levels over time to help doctors more accurately assess his risk of life-threatening prostate cancer. (Source: EurekAlert! - Medicine and Health)

Triglyceride levels predict stroke risk in postmenopausal women

EurekAlert! - Social and Behavioral Science — Thu, 02 Feb 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) A new study by researchers at NYU Langone Medical Center and colleagues found that traditional risk factors for stroke -- such as high cholesterol -- are not as accurate at predicting risk in postmenopausal women as previously thought. Instead, researchers say doctors should refocus their attention on triglyceride levels to determine which women are at highest risk of suffering a devastating and potentially fatal cardiovascular event. (Source: EurekAlert! - Social and Behavioral Science)

Sexual Risk Taking in Relation to Sexual Identification, Age, and Education in a Diverse Sample of African American Men Who Have Sex with Men (MSM) in New York City

AIDS and Behavior — Wed, 01 Feb 2012 17:12:53 +0100

Abstract HIV disproportionately affects African American men who have sex with men (MSM) in the United States. To inform this epidemiological pattern, we examined cross-sectional sexual behavior data in 509 African American MSM. Bivariate logistic regression analyses were conducted to examine the extent to which age, education, and sexual identity explain the likelihood of engaging in sex with a partner of a specific gender and the likelihood of engaging in unprotected sexual behaviors based on partner gender. Across all partner gender types, unprotected sexual behaviors were more likely to be reported by men with lower education. Younger, non-gay identified men were more likely to engage in unprotected sexual behaviors with transgender partners, while older, non-gay ident...

Q&A: The instrumentalist

Nature — Wed, 01 Feb 2012 05:00:00 +0100

Nature 482, 7383 (2012). doi:10.1038/482034a Author: Jascha Hoffman Cognitive psychologist Gary Marcus researches language acquisition and the evolution of the brain at New York University. On the release of his latest book, Guitar Zero — a personal yet scientific investigation of how people become musical — he explains how a love of music and a computer game helped him to overcome a lack of rhythm and learn to play the guitar. (Source: Nature)

New Cornell Campus to Cultivate High-Tech Industry in New York City [Slide Show]

Scientific American Topic - Biotechnology — Tue, 31 Jan 2012 12:00:00 +0100

For years New York City–based universities have been opening satellite campuses worldwide, whether it is New York University's sites in Abu Dhabi and Tel Aviv or Columbia University's Global Centers in Beijing and Nairobi. Technion–Israel Institute of Technology in Haifa is returning the favor in a big way, partnering with Ithaca, N.Y.–based Cornell University to build a campus on New York City's Roosevelt Island . [More] (Source: Scientific American Topic - Biotechnology)

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Erratum to: Acamprosate modulates experimental autoimmune encephalomyelitis

Inflammopharmacology — Tue, 24 Jan 2012 12:27:04 +0100

Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s10787-012-0120-1Authors Z. Sternberg, Department of Neurology, Baird MS Center, Jacobs Neurological Institute, 100 High Street, Buffalo, NY 14203, USAA. Cesario, Department of Neurology, Baird MS Center, Jacobs Neurological Institute, 100 High Street, Buffalo, NY 14203, USAK. Rittenhouse-Olson, Department of Biotechnical and Neurological Laboratory Sciences, University of Buffalo, 3435 Main Street, Buffalo, NY, USAR. A. Sobel, Department of Pathology, VA Health Care System, 3801 Miranda Avenue, Palo Alto, CA, USAYi-Kan Leung, Department of Neurology, Baird MS Center, Jacobs Neurological Institute, 100 High Street, Buffalo, NY 14203, USAO. Pankewycz, Department of Surgery, Buffalo General Hospital, State University of New...

Y chromosome haplogroups and prostate cancer in populations of European and Ashkenazi Jewish ancestry

Human Genetics — Tue, 24 Jan 2012 07:34:54 +0100

Abstract Genetic variation on the Y chromosome has not been convincingly implicated in prostate cancer risk. To comprehensively analyze the role of inherited Y chromosome variation in prostate cancer risk in individuals of European ancestry, we genotyped 34 binary Y chromosome markers in 3,995 prostate cancer cases and 3,815 control subjects drawn from four studies. In this set, we identified nominally significant association between a rare haplogroup, E1b1b1c, and prostate cancer in stage I (P = 0.012, OR = 0.51; 95% confidence interval 0.30–0.87). Population substructure of E1b1b1c carriers suggested Ashkenazi Jewish ancestry, prompting a replication phase in individuals of both European and Ashkenazi Jewish ancestry. The association was not signific...

Confidence, positive feelings support better medication adherence in hypertensive African-Americans

EurekAlert! - Medicine and Health — Mon, 23 Jan 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) When it comes to taking prescribed medications for hypertension, a patient's self confidence could be as important as doctor's orders. A new study by researchers at NYU School of Medicine reveals that positive affirmation, when coupled with patient education, seems to help patients more effectively follow their prescribed medication regimen. (Source: EurekAlert! - Medicine and Health)

Can A Middle-Aged Neophyte Make It to Carnegie Hall?

Scientific American - Official RSS Feed — Sat, 21 Jan 2012 12:00:00 +0100

Gary Marcus suffers from what a friend jokingly describes as congenital arrhythmia--the inability, despite many hours of his youth spent practicing and taking lessons, to learn to play a musical instrument. A few years ago Marcus, a cognitive psychologist at New York University, decided at 38 to make one last try when he took up guitar. No surprise: He did not succeed in becoming the next Jimi Hendrix, but managed to acquire a modicum of skill--and went on to describe his experience in Guitar Zero: The New Musician and the Science of Learning . [More] (Source: Scientific American - Official RSS Feed)

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Enrollment in Clinical Trials Correlates with Improved Survival in Metastatic Melanoma.

Oncology — Fri, 20 Jan 2012 05:00:00 +0100

Conclusion: Our data suggest that enrollment in clinical trials independently correlates with prolonged survival after a diagnosis of stage IV melanoma. PMID: 22270052 [PubMed - as supplied by publisher] (Source: Oncology)

Opportunities for Cost Reduction of Medical Care: Part 3

Journal of Community Health — Thu, 19 Jan 2012 06:54:50 +0100

Abstract The level of health care spending in the United States and other developed nations is rising at a disturbingly rapid rate. However, in the United States, these increases are not justified by superior performance. Rather, most other wealthy countries’ inhabitants live longer and suffer from fewer medical problems than the average American. This paper demonstrates the continued abundance of opportunities for substantially reducing health care costs without decreasing the quality of care. In particular, it emphasizes the need to reduce the practice of defensive medicine and to enlarge the cadre of non-specialist physicians who educate future doctors. Such cost-saving opportunities are not rare phenomena but are widely available and offer the United States opportuni...

Person Mobility in the Design and Analysis of Cluster-Randomized Cohort Prevention Trials

Prevention Science — Tue, 17 Jan 2012 07:07:55 +0100

Abstract Person mobility is an inescapable fact of life for most cluster-randomized (e.g., schools, hospitals, clinic, cities, state) cohort prevention trials. Mobility rates are an important substantive consideration in estimating the effects of an intervention. In cluster-randomized trials, mobility rates are often correlated with ethnicity, poverty and other variables associated with disparity. This raises the possibility that estimated intervention effects may generalize to only the least mobile segments of a population and, thus, create a threat to external validity. Such mobility can also create threats to the internal validity of conclusions from randomized trials. Researchers must decide how to deal with persons who leave study clusters during a trial (dropouts), p...

Virtual exercise better for pensioners' minds and bodies, study finds

Telegraph Health — Mon, 16 Jan 2012 15:44:47 +0100

Pensioners should play Wii Fit rather than going for walks because virtual reality exercise slows mental as well as physical decline, a New York university study finds. (Source: Telegraph Health)

Researchers use sugar to halt esophageal cancer in its tracks

EurekAlert! - Medicine and Health — Sun, 15 Jan 2012 05:00:00 +0100

(New York University) Scientists working at the Medical Research Council have identified changes in the patterns of sugar molecules that line pre-cancerous cells in the esophagus, a condition called Barrett's dysplasia, making it much easier to detect and remove these cells before they develop into esophageal cancer. These findings have important implications for patients and may help to monitor their condition and prevent the development of cancer. (Source: EurekAlert! - Medicine and Health)

Emotion Selectively Distorts Our Recollections (preview)

Scientific American - Official RSS Feed — Thu, 12 Jan 2012 12:00:00 +0100

On September 11, 2001, Elizabeth A. Phelps stepped outside her apartment in lower Manhattan and noticed a man staring toward the World Trade Center, about two miles away. Looking up, “I just saw this big, burning hole,” Phelps recalls. The man told her that he had just seen a large airplane crash into one of the skyscrapers. Thinking it was a horrible accident, Phelps started walking to work, a few blocks away, for a 9 a.m. telephone meeting. By the time she reached her eighth-floor office at New York University, a second jet had struck the other tower, which collapsed after an hour. Later, she saw the remaining tower fall. [More] (Source: Scientific American - Official RSS Feed)

New culprit discovered in T-cell acute lymphoblastic leukemia

EurekAlert! - Medicine and Health — Thu, 12 Jan 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) A new study published in the journal Nature Medicine by NYU Cancer Institute researchers, shows how the cancer causing gene Notch, in combination with a mutated Polycomb Repressive Complex 2 protein complex, work together to cause T- cell acute lymphoblastic leukemia. (Source: EurekAlert! - Medicine and Health)

Cardiovascular biology: Stranded cells fuel plaques

Nature — Wed, 11 Jan 2012 05:00:00 +0100

Nature 481, 7380 (2012). doi:10.1038/481116c One contributor to the build-up of fatty plaques in artery walls is a signalling protein that blocks the emigration of a major plaque constituent from the deposits.Fat-laden white blood cells called macrophages are abundant in atherosclerotic plaques. Kathryn Moore at New York University and (Source: Nature)

Researchers discover new culprit in atherosclerosis

EurekAlert! - Medicine and Health — Sun, 08 Jan 2012 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) A new study by NYU Langone Medical Center researchers identified a new culprit that leads to atherosclerosis, the accumulation of fat and cholesterol that hardens into plaque and narrows arteries. The research explains why cholesterol-laden, coronary artery disease-causing cells called macrophages, accumulate in artery plaques. (Source: EurekAlert! - Medicine and Health)

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Slipstream: The Human Anatomy, Animated With 3-D Technology

NYT Health — Sat, 07 Jan 2012 20:22:17 +0100

A 3-D virtual body, now used by medical students in anatomy studies, represents an unusual collaboration between industry and academia. (Source: NYT Health)

Serum sphingolipids and inflammatory mediators in adolescents at risk for metabolic syndrome

Endocrine — Fri, 06 Jan 2012 16:44:53 +0100

Abstract The purpose of this study was to determine low-grade inflammation associated with obesity that is mediated partially by TNF-α, an adipocytokine which stimulates sphingomyelinase activity in adipocytes. Circulating ceramide (Cer) and sphingosine 1-phosphate (S1P) are elevated in genetically obese (ob/ob) mice. We aimed to determine whether serum sphingolipid concentrations correlate with measures of obesity, insulin resistance, and lipid profiles in overweight versus lean adolescents. This cross-sectional study recruited 30 healthy overweight (body mass index, BMI ≥ 85%) and 15 lean (BMI 10–84%) adolescents. Anthropometric measurements and fasting blood samples were collected at one clinic visit. Serum glucose, insulin, and fasting lipid profiles were...

HHS Panel on Antiretroviral Guidelines for Adults and Adolescents Announces New Members

Fri, 06 Jan 2012 05:00:00 +0100

The HHS Panel on Antiretroviral Guidelines for Adults and Adolescents (a working group of the Office of AIDS Research Council) is pleased to welcome four new members to the Panel. The new members will begin a 4-year term starting in March 2012. Judith Aberg, M.D. (New York University) Adaora Adimora, M.D., M.P.H. (University of North Carolina) Phyllis Tien, M.D., M.S. (University of California, San Francisco) Rochelle Walensky, M.D., M.P.H. (Massachusetts General Hospital/Harvard Medical School) (Source: AIDSinfo At-a-Glance: Offering Information on HIV/AIDS Treatment, Prevention, and Research, A Service of the U.S. Department of Health and Human Services (DHHS))

Spectrums of Love: Examining the Relationship between Romantic Motivations and Sexual Risk among Young Gay and Bisexual Men

AIDS and Behavior — Thu, 05 Jan 2012 17:05:02 +0100

We examined the association between HIV/AIDS risk behaviors and romantic feelings among single, young gay and bisexual men (YGBM). Romantic feelings may have positive (romantic ideation) and negative (romantic obsession) connotations. Consequently, we hypothesized that YGBM would report greater risks if they reported having obsessive thoughts about their relationship desires; conversely, we hypothesized that YGBM who envision a romantic relationship would report fewer unprotected partners. Using cross-sectional data from a study examining YGBM’s online dating experiences (N = 376; ages 18–24), we found a positive association between romantic obsession and number of partners for unprotected receptive (URAI) and insertive (UIAI) anal intercourse. Conversely, we found a neg...

Erratum to: Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma

Investigational New Drugs — Mon, 02 Jan 2012 16:54:32 +0100

Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s10637-011-9780-8Authors Jason Konner, Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USARachel N. Grisham, Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USAJae Park, Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USAOwen A. O’Connor, New York University Cancer Institute, New York, NY, USAGillian Cropp, Nereus Pharmaceuticals, Inc, San Diego, CA, USARobert Johnson, Aeolian Biomed, Lafayette, CA, USAAlison L. Hannah, Nereus Pharmaceuticals, Inc, ...

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The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers

Breast Cancer Research and Treatment — Mon, 02 Jan 2012 16:49:44 +0100

Abstract Klotho (KL) is a putative tumor suppressor gene in breast and pancreatic cancers located at chromosome 13q12. A functional sequence variant of Klotho (KL-VS) was previously reported to modify breast cancer risk in Jewish BRCA1 mutation carriers. The effect of this variant on breast and ovarian cancer risks in non-Jewish BRCA1/BRCA2 mutation carriers has not been reported. The KL-VS variant was genotyped in women of European ancestry carrying a BRCA mutation: 5,741 BRCA1 mutation carriers (2,997 with breast cancer, 705 with ovarian cancer, and 2,039 cancer free women) and 3,339 BRCA2 mutation carriers (1,846 with breast cancer, 207 with ovarian cancer, and 1,286 cancer free women) from 16 centers. Genotyping was accomplished using TaqMan® allelic discrimination or m...

Verbal memory capacity after treatment for ruptured intracranial aneurysm—the outcomes of three psychological tests: within a month, 1 year after and 5-7 years after treatment

Acta Neurochirurgica — Fri, 30 Dec 2011 16:50:10 +0100

Conclusions The results of the study imply the need for long-term rehabilitation of memory in this particular group of patients. Content Type Journal ArticleCategory Clinical ArticlePages 1-6DOI 10.1007/s00701-011-1256-2Authors Marek Preiss, Prague Psychiatric Center, University of New York in Prague, Prague, Czech RepublicJana Koblihová, Central Medical-Psychological Division, Central Military Hospital, Prague, Czech RepublicDavid Netuka, Department of Neurosurgery, Charles University, 1st Medical Faculty, Central Military Hospital, U Vojenske nemocnice 1200, Prague 6, Czech RepublicLenka Bernardová, Department of Neurosurgery, Charles University, 1st Medical Faculty, Central Military Hospital, U Vojenske nemocnice 1200, Prague 6, Czech RepublicFrantišek Charvát, R...

Educating a New Generation of Social Workers: Challenges and Skills Needed for Contemporary Agency-Based Practice

Clinical Social Work Journal — Fri, 30 Dec 2011 07:08:58 +0100

Abstract Schools of social work are continually challenged to provide professional training which effectively prepares students for the ever-changing and increasingly demanding contemporary practice context. This paper provides an overview of emerging clinical, organizational, and research trends and challenges within agency-based social work practice in the past decade. Implications of these changes for the profession will be discussed and recommendations will be offered for ways in which academic and field educators can best equip social work students with the skills needed to meet these challenges of the current agency-based practice context. These recommendations for social work practice, education, and research include the development of an integrated set of clinical,...

Erratum to: Left laparoscopic paraduodenal hernia repair

Surgical Endoscopy — Fri, 30 Dec 2011 06:50:26 +0100

Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s00464-011-2100-8Authors Abed Khalaileh, Department of Surgery, Hadassah Hebrew University Medical Center, Kiryat Hadassah, P.O.B. 12000, 91120 Jerusalem, IsraelAvraham Schlager, Department of Surgery, New York University Hospital, New York, NY, USAMiklosh Bala, Department of Surgery, Hadassah Hebrew University Medical Center, Kiryat Hadassah, P.O.B. 12000, 91120 Jerusalem, IsraelSamir Abu-Gazala, Department of Surgery, Hadassah Hebrew University Medical Center, Kiryat Hadassah, P.O.B. 12000, 91120 Jerusalem, IsraelRam Elazary, Department of Surgery, Hadassah Hebrew University Medical Center, Kiryat Hadassah, P.O.B. 12000, 91120 Jerusalem, IsraelAvraham I. Rivkind, Department of Surgery, Hadassah Hebrew University Medical...

Bay846, a new irreversible small molecule inhibitor of EGFR and Her2, is highly effective against malignant brain tumor models

Investigational New Drugs — Wed, 28 Dec 2011 06:53:28 +0100

Summary The epidermal growth factor receptor (EGFR) pathway is aberrantly activated in tumors and plays a key role in promoting tumor growth. Small molecule inhibitors which bind reversibly to EGFR have demonstrated limited clinical activity. Thus, there is a continued need to develop novel EGFR inhibitors with improved anti-tumor activity. Bay846 is a newly developed small molecule inhibitor that binds irreversibly to the tyrosine kinase domains of EGFR and Her2. The in vitro and in vivo efficacy of Bay846 was tested using a panel of nine human malignant brain tumor (glioma) models. Lapatinib, a reversible inhibitor of EGFR and Her2, was included for comparison. Six glioma cell lines were sensitive to Bay846 treatment. Bay846 strongly suppressed tumor cell growth in vitro ...

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Chemotherapy response and recurrence-free survival in neoadjuvant breast cancer depends on biomarker profiles: results from the I-SPY 1 TRIAL (CALGB 150007/150012; ACRIN 6657)

Breast Cancer Research and Treatment — Sat, 24 Dec 2011 16:42:11 +0100

Abstract Neoadjuvant chemotherapy for breast cancer allows individual tumor response to be assessed depending on molecular subtype, and to judge the impact of response to therapy on recurrence-free survival (RFS). The multicenter I-SPY 1 TRIAL evaluated patients with ≥3 cm tumors by using early imaging and molecular signatures, with outcomes of pathologic complete response (pCR) and RFS. The current analysis was performed using data from patients who had molecular profiles and did not receive trastuzumab. The various molecular classifiers tested were highly correlated. Categorization of breast cancer by molecular signatures enhanced the ability of pCR to predict improvement in RFS compared to the population as a whole. In multivariate analysis, the molecular signatu...

Human Microbiome and HIV/AIDS

Current HIV/AIDS Reports — Thu, 22 Dec 2011 12:51:53 +0100

Abstract Understanding of the human microbiome continues to grow rapidly; however, reports on changes in the microbiome after HIV infection are still limited. This review surveys the progress made in methodology associated with microbiome studies and highlights the remaining challenges to this field. Studies have shown that commensal oral, gut, vaginal, and penile bacteria are vital to the health of the human immune system. Our studies on crosstalk among oral and gastrointestinal soluble innate factors, HIV, and microbes indicated that the oral and gut microbiome was altered in the HIV-positive samples compared to the negative controls. The importance of understanding the bacterial component of HIV/AIDS, and likelihood of “crosstalk” between viral and bacterial pathoge...

What Makes Wings Work?

NPR Health and Science — Fri, 16 Dec 2011 18:00:00 +0100

Researchers at New York University are studying flight with a speaker, a soup pot, straws and a box full of paper aircraft. Emeritus professor Stephen Childress describes the experiment and what he and his colleagues have learned about flight from their homemade flying objects.» E-Mail This » Add to Del.icio.us (Source: NPR Health and Science)

Disorder of Extreme Stress and Complex Trauma

Psychology Today Anxiety Center — Wed, 14 Dec 2011 08:17:16 +0100

Experts in the field of chronic trauma emphasize the importance of creating an emotional comfort zone for victims. Primary Topic: Anxiety read more (Source: Psychology Today Anxiety Center)

Cholesterol-Lowering Medication Accelerates Depletion of Plaque in Arteries

Diabetes News from dLife.com — Tue, 13 Dec 2011 19:42:47 +0100

December 13, 2011 (New York University Langone Medical Center) — New study reveals molecular mechanism promoting the breakdown of plaque by statins. read more (Source: Diabetes News from dLife.com)

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Higgs boson seminar: have physicists found the 'god particle'?

Guardian Unlimited Science — Tue, 13 Dec 2011 17:24:00 +0100

Conclusion: more data needed.3.37pm: Rolf Heuer sits down with Guido Tonelli of CMS to begin the press conference. Camera bulbs flashing everywhere. I assume this is what it's like at all science seminars, yes?3.40pm: Press conference begins. If you have questions, you can tweet them to the Cern press office with the hashtag #higgsupdate"We need many more collisions to get the Shakespeare answer to the Higgs: to be or not to be," says Heuer.Fabiola Gianotti – leader of the Atlas experiment – speaks first, says that what we have seen today is only part of the Atlas science programme. "It's too early to tell if the success is due to the fluctuations in the backgtround or if it's due to something more interesting."Guido Tonelli, in charge of the CMS experiment, says: "We are discussing th...

Cholesterol-lowering medication accelerates depletion of plaque in arteries

EurekAlert! - Social and Behavioral Science — Tue, 13 Dec 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) In a new study, NYU Langone Medical Center researchers have discovered how cholesterol-lowering drugs called statins promote the breakdown of plaque in the arteries. (Source: EurekAlert! - Social and Behavioral Science)

Clive Robbins, Developer of Influential Method of Music Therapy, Dies at 84

NYT Health — Tue, 13 Dec 2011 04:30:16 +0100

Mr. Robbins, with Paul Nordoff, designed a brand of music therapy for hard-to-reach children that is now used to help people with autism, stroke and Alzheimer’s disease. (Source: NYT Health)

Stress during second and third month of pregnancy raise risk of premature birth and losing baby boys

the Mail online | Health — Fri, 09 Dec 2011 17:17:06 +0100

A new study from New York University shows exposure to stress can shorten the length of pregnancy, making it more likely that babies will be born early and for boys to be miscarried. (Source: the Mail online | Health)

New registered nurses' lack of geographic mobility has negative implications for rural health

EurekAlert! - Medicine and Health — Fri, 09 Dec 2011 05:00:00 +0100

(New York University) A study on the geographic mobility of registered nurses recently published in the December Health Affairs magazine suggests that the profession's relative lack of mobility has serious implications for access to health care for people in rural areas. (Source: EurekAlert! - Medicine and Health)

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Neuroscientists Find Greater Complexity In How We Perceive Motion

Health News from Medical News Today — Wed, 07 Dec 2011 08:00:00 +0100

How we perceive motion is a significantly more complex process than previously thought, researchers at New York University's Center for Neural Science, Stanford University and the University of Washington have found. Their results, which appear in the journal Current Biology, show that the relationship between the brain and visual perception varies, depending on the type of motion we are viewing. Neuroscientists have posited that our perception of motion is derived from a relatively simple process - that is, it relies on a single cortical area in the brain... (Source: Health News from Medical News Today)

An adventure in dermatology: A personal history

Clinics in Dermatology — Wed, 07 Dec 2011 06:09:34 +0100

Abstract: This adventure in dermatology took place between 1960 and 1962. An immigration ruling forced Dr Bernard Gordon, a Canadian, to spend 2 years abroad before he could legally live and practice in the United States. Dr Gordon had just completed a 3-year residency at the New York University Skin and Cancer Unit. Dr Gordon met with his mentor, Dr Marion Sulzberger, for advice. This world-famous dermatologist took an interest in his situation and was able to arrive at an extraordinary solution. Dr Sulzberger consulted with his many dermatology colleagues and made arrangements for Dr Gordon to work abroad. He would spend 1 year in Caracas, Venezuela, teaching and conducting research in tropical skin diseases. The second year would be spent in Europe, beginning with 3 months in Madrid, Sp...

Cardiac output monitoring devices: an analytic review

Internal and Emergency Medicine — Tue, 06 Dec 2011 17:02:13 +0100

Abstract To evaluate cardiac output (CO), both invasive and semi-invasive monitors are used in critical care medicine. The pulmonary artery catheter is an invasive tool to assess CO with the major criticism that the level of its invasiveness is not supported by an improvement in patients’ outcomes. The interest in a lesser invasive techniques is high. Therefore, alternative techniques have been developed recently, and are used frequently in critical care medicine. Cardiac output can be monitored continuously by different devices that analyze the stroke volume and CO. The purpose of this review is to understand these new technologies and their applications and limitations. Content Type Journal ArticleCategory EM - REVIEWPages 1-9DOI 10.1007/s11739-011-0738-9Authors ...

Effects of protein kinase A inhibitor and activator on rewarding effects of SKF-82958 microinjected into nucleus accumbens shell of ad libitum fed and food-restricted rats

Psychopharmacology — Tue, 06 Dec 2011 06:59:28 +0100

Conclusions Results indicate that inhibition of PKA enhances the unconditioned rewarding effect of D-1 receptor stimulation and that decreased PKA may be involved in the effect of FR on drug reward. Evidence for involvement of D-2 receptor-expressing neurons in the enhancing effect of PKA inhibition is discussed. Content Type Journal ArticleCategory Original InvestigationPages 1-11DOI 10.1007/s00213-011-2602-zAuthors Soledad Cabeza de Vaca, Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USAXing-Xiang Peng, Department of Psychiatry, New York University School of Medicine, 550 First Avenue, New York, NY 10016, USASeth Concors, Department of Psychiatry, New York University School of Medicine, 550 First Avenue, Ne...

Neuroscientists find greater complexity in how we perceive motion

EurekAlert! - Social and Behavioral Science — Mon, 05 Dec 2011 05:00:00 +0100

(New York University) How we perceive motion is a significantly more complex process than previously thought, researchers at NYU's Center for Neural Science, Stanford University and the University of Washington have found. Their results show that the relationship between the brain and visual perception varies, depending on the type of motion we are viewing. (Source: EurekAlert! - Social and Behavioral Science)

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Some Atheist Scientists With Children Embrace Religious Traditions, According To New Rice Research

Health News from Medical News Today — Sun, 04 Dec 2011 08:00:00 +0100

Study reveals 17 percent of atheists with children are involved in religious institutions for social and personal reasons Some atheist scientists with children embrace religious traditions for social and personal reasons, according to research from Rice University and the University at Buffalo -- The State University of New York (SUNY). The study also found that some atheist scientists want their children to know about different religions so their children can make informed decisions about their own religious preferences... (Source: Health News from Medical News Today)

Resident protection

The Rockefeller University Newswire — Thu, 01 Dec 2011 21:13:03 +0100

To keep the body safe, the immune system enlists more than one form of protection. Rockefeller University scientists, working in collaboration with researchers at New York University, are learning about an important, but little-known, network of dendritic cells in lymph nodes through innovative, live-action imaging. More » (Source: The Rockefeller University Newswire)

Lack of association between common single nucleotide polymorphisms in the TERT-CLPTM1L locus and breast cancer in women of African ancestry

Breast Cancer Research and Treatment — Thu, 01 Dec 2011 19:29:06 +0100

Abstract As one of the most common cancers worldwide, breast cancer places an extraordinary burden on the populations of African ancestry. Common SNPs in the TERT-CLPTM1L locus have been reported to be associated with several types of cancer, including breast cancer. We sought to investigate whether the previously reported common single nucleotide polymorphisms (SNPs) in the TERT-CLPTM1L locus could also contribute to the breast cancer risk in women of African ancestry. We genotyped eleven SNPs in 2,892 women of African descent but were unable to detect any significant association between TERT-CLPTM1L SNPs and their predispositions for breast cancer risk. Given the differences in linkage disequilibrium patterns across populations, our findings suggest that larger independent...

The Alexander Discipline, Volume 2: Long-term stability

American Journal of Orthodontics and Dentofacial Orthopedics — Thu, 01 Dec 2011 05:00:00 +0100

Dr Alexander has been a major contributor to clinical orthodontics for many years. Also a longtime faculty member, he is currently a clinical professor of orthodontics at Baylor in Dallas, the University of Texas in Houston, and New York University. (Source: American Journal of Orthodontics and Dentofacial Orthopedics)

Some atheist scientists with children embrace religious traditions, according to new Rice research

EurekAlert! - Social and Behavioral Science — Thu, 01 Dec 2011 05:00:00 +0100

(Rice University) Some atheist scientists with children embrace religious traditions for social and personal reasons, according to research from Rice University and the University at Buffalo -- the State University of New York. (Source: EurekAlert! - Social and Behavioral Science)

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Teaching cardiac electrophysiology modeling to undergraduate students: laboratory exercises and GPU programming for the study of arrhythmias and spiral wave dynamics.

Advances in Physiology Education — Thu, 01 Dec 2011 05:00:00 +0100

Authors: Bartocci E, Singh R, von Stein FB, Amedome A, Caceres AJ, Castillo J, Closser E, Deards G, Goltsev A, Ines RS, Isbilir C, Marc JK, Moore D, Pardi D, Sadhu S, Sanchez S, Sharma P, Singh A, Rogers J, Wolinetz A, Grosso-Applewhite T, Zhao K, Filipski AB, Gilmour RF, Grosu R, Glimm J, Smolka SA, Cherry EM, Clarke EM, Griffeth N, Fenton FH Abstract As part of a 3-wk intersession workshop funded by a National Science Foundation Expeditions in Computing award, 15 undergraduate students from the City University of New York(1) collaborated on a study aimed at characterizing the voltage dynamics and arrhythmogenic behavior of cardiac cells for a broad range of physiologically relevant conditions using an in silico model. The primary goal of the workshop was to cultivate student inte...

Improving patient care by improving nurses' work environment

EurekAlert! - Social and Behavioral Science — Wed, 30 Nov 2011 05:00:00 +0100

(New York University) A study published in the current issue of Health Care Management Review indicates that there are other aspects of registered nurses' (RNs) work environments that RNs perceive can also have a significant impact on the quality of care they deliver. In order of influence, those factors are: physical work environment, workgroup cohesion, nurse-physician relations, procedural justice and job satisfaction. Nurses' ratings of patient care quality were also higher in hospitals with Magnet recognition programs. (Source: EurekAlert! - Social and Behavioral Science)

Design, baseline characteristics, and early findings of the MPS VI (mucopolysaccharidosis VI) Clinical Surveillance Program (CSP)

Journal of Inherited Metabolic Disease — Wed, 30 Nov 2011 04:36:22 +0100

Conclusions The CSP represents the largest cross-sectional study of MPS VI to date. This first report provides information on the design and implementation of the program and population statistics for several clinical variables in patients with MPS VI. Data collected over 5 years suggest that ERT provides clinical benefit and is well-tolerated with no new safety concerns. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s10545-011-9410-9Authors Christian J. Hendriksz, Birmingham Children’s Hospital, Birmingham, UKRoberto Giugliani, Department of Genetics/UFRGS, Medical Genetics Service/HCPA and INAGEMP, Porto Alegre, BrazilPaul Harmatz, Children’s Hospital & Research Center Oakland, Oakland, CA, USAChristina Lampe, Villa Metabolica...

Stress response predictor in police officers may indicate those at high risk for PTSD

EurekAlert! - Social and Behavioral Science — Tue, 29 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) A study led by Dr. Charles Marmar, professor and chair of the Department of Psychiatry at the NYU Langone Medical Center, is one of the largest to identify a possible method for predicting vulnerability to stress during and after a traumatic event. (Source: EurekAlert! - Social and Behavioral Science)

NYU Steinhardt researchers receive $1.2 million grant to assess impact of head start programs

EurekAlert! - Social and Behavioral Science — Tue, 29 Nov 2011 05:00:00 +0100

(New York University) Researchers at New York University's Steinhardt School of Culture, Education, and Human Development have received a $1.2 million grant from the Administration for Children and Families to assess Head Start programs. (Source: EurekAlert! - Social and Behavioral Science)

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Launch of ‘living’ books breaks barriers between humanities and science

MEDEV News — Mon, 28 Nov 2011 13:28:57 +0100

A series of 21 ‘living books’ has been launched online as part of a pioneering initiative designed to provide a bridge between the humanities and the sciences. The Living Books About Life series is written and produced by humanities scholars from universities across the world – from the UK and America to Poland and Australia – and has re-packaged and re-presented science-related research material to make it more accessible to a humanities audience. Funded by JISC and published by the Open Humanities Press (OHP), the books address a number of scientific topics whose unifying theme is life, including air, agriculture, bioethics, cosmetic surgery, energy, neurology and human cloning. Alastair Dunning, programme manager at JISC, said: "By drawing only on Open Acces...

New potential therapeutic target identified for Diffuse Large B-Cell Lymphoma

EurekAlert! - Medicine and Health — Mon, 28 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have discovered a new potential therapeutic target for Diffuse Large B-Cell Lymphoma, the most aggressive and common type of lymphoma in adults. The new study, published in the Nov. 23 issue of Nature, reveals the underlying molecular mechanism contributing to the development of lymphomagenesis. (Source: EurekAlert! - Medicine and Health)

NYU Langone experts present at annual meeting of Radiological Society of North America

EurekAlert! - Medicine and Health — Mon, 28 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Experts from the Department of Radiology at NYU Langone Medical Center will present new research and advanced imaging techniques at the 97th Scientific Assembly and Annual Meeting of the Radiology Society of North America in Chicago, Nov. 27 - Dec. 2, 2011. (Source: EurekAlert! - Medicine and Health)

Researchers Find Men Less Willing To Be Screened For Cancer

Health News from Medical News Today — Sat, 26 Nov 2011 08:00:00 +0100

Although men have higher cancer mortality rates than women, they are less willing to be screened for cancer, according to a study conducted by researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues at Sanoa Consulting LLC, Muscle Shoals, Ala., and the New York University College of Dentistry... (Source: Health News from Medical News Today)

Assessment of Hospital Disaster Preparedness for the 2010 FIFA World Cup Using an Internet-Based, Long-Distance Tabletop Drill. - Valesky W, Silverberg M, Gillett B, Roblin P, Adelaine J, Wallis LA, Smith W, Arquilla B.

SafetyLit: All (Unduplicated) — Sat, 26 Nov 2011 00:42:13 +0100

Introduction: The State University of New York at Downstate (SUNY) conducted a web-based long-distance tabletop drill (LDTT) designed to identify vulnerabilities in safety, security, communications, supplies, incident management, and surge capacity for a n... (Source: SafetyLit: All (Unduplicated))

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Sacro-femoral-pubic angle: a coronal parameter to estimate pelvic tilt

European Spine Journal — Thu, 24 Nov 2011 06:49:46 +0100

Conclusion The pelvic tilt is an essential measure in the context of radiographic evaluation of spinal deformity and malalignment. Given the routinely excellent visibility of coronal films this study established the SFP as a coronal parameter which can reliably estimate pelvic tilt. The high correlation and predictive ability of the SFP angle should prompt further study and clinical application when lateral radiographs do not permit assessment of pelvic parameters. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00586-011-2061-6Authors Benjamin Blondel, Spine Division, Hospital for Joint Diseases, New York University, New York, USAFrank Schwab, Spine Division, Hospital for Joint Diseases, New York University, New York, USAAshish Patel, Sp...

Researchers Find Men Less Willing To Be Screened For Cancer

Health News from Medical News Today — Wed, 23 Nov 2011 09:00:00 +0100

Report Provides New Analysis of Carbon Accounting, Biomass Use, and Climate Benefits

Public Policy Reports — Wed, 23 Nov 2011 07:41:40 +0100

A recent report tackles the latest science regarding carbon accounting, biomass use, and forest carbon offsets. The authors, which include a team of researchers from the U.S. Forest Service, found that sustainably managed forests can provide carbon storage, forest products can reduce carbon emissions, and forest biomass-based energy can reduce the flow of fossil fuel-based carbon emissions into the atmosphere. “This work should help policymakers reconsider the critical impact forests have on our daily lives and the potential they have to solve problems that confront our Nation,” says lead author Bob Malmsheimer of the State University of New York. The report can be found in the October/November issue of the Journal of Forestry. (Source: Public Policy Reports)

Employment After a Breast Cancer Diagnosis: A Qualitative Study of Ethnically Diverse Urban Women

Journal of Community Health — Tue, 22 Nov 2011 17:59:46 +0100

Abstract Employment status is related to treatment recovery and quality of life in breast cancer survivors, yet little is known about return to work in immigrant and minority survivors. We conducted an exploratory qualitative study using ethnically cohesive focus groups of urban breast cancer survivors who were African-American, African-Caribbean, Chinese, Filipina, Latina, or non-Latina white. We audio- and video-recorded, transcribed, and thematically coded the focus group discussions and we analyzed the coded transcripts within and across ethnic groups. Seven major themes emerged related to the participants’ work experiences after diagnosis: normalcy, acceptance, identity, appearance, privacy, lack of flexibility at work, and employer support. Maintaining a sense of n...

Moffitt Cancer Center researchers find men less willing to be screened for cancer

EurekAlert! - Medicine and Health — Tue, 22 Nov 2011 05:00:00 +0100

(H. Lee Moffitt Cancer Center & Research Institute) Although men have higher cancer mortality rates than women, they are less willing to be screened for cancer, according to a study conducted by researchers at Moffitt Cancer Center in Tampa, Fla., and colleagues at Sanoa Consulting LLC, Muscle Shoals, Ala., and the New York University College of Dentistry. (Source: EurekAlert! - Medicine and Health)

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Dendritic cells protect against acute pancreatitis

EurekAlert! - Medicine and Health — Tue, 22 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) NYU Langone Medical Center researchers have discovered the novel protective role dendritic cells play in the pancreas. The new study, published in the November issue of journal Gastroenterology, shows dendritic cells can safeguard the pancreas against acute pancreatitis, a sudden dangerous swelling and inflammation of the pancreas gland. (Source: EurekAlert! - Medicine and Health)

Update on the Amplatzer Duct Occluder: A 10-Year Experience in Asia

Pediatric Cardiology — Mon, 21 Nov 2011 17:53:35 +0100

Abstract Few data exist regarding the efficacy and safety of the Amplatzer ductal occluder (ADO) type 1 device in the Asian region. This retrospective study, conducted between August 2001 and April 2011, attempted device placement for 231 patients (165 females and 66 males) with a median age of 7.4 years (range, 3 months to 64 years) and an average weight of 19.4 kg (range, 4.1–81.0 kg). Among the patients in this study, 66 (28.6%) had pulmonary hypertension, ten (4.3%) had trisomy 21, and eight (3.5%) had other congenital cardiac anomalies. The mean narrowest patent ductus arteriosus (PDA) diameter was 4.2 mm (range, 1.3–10 mm), and the ampulla size was 9.6 mm (range, 4–20 mm). Successful implantation was achieved for 229 ...

Sense Of Smell May Improve With Training

Health News from Medical News Today — Mon, 21 Nov 2011 11:00:00 +0100

People who notice their sense of smell is not as good as it used to be may wish to take note of what scientists training laboratory rats concluded: a failing sense of smell can improve, however, it can also get worse, depending on the type of training. Drs Julie Chapuis and Donald A Wilson from New York University (NYU) Langone School of Medicine write about their findings in the 20 November online issue of Nature Neuroscience. They hope their discovery will help develop new ways to reverse the loss of smell that occurs with age or disease... (Source: Health News from Medical News Today)

In the Minds of Others (preview)

Scientific American - Official RSS Feed — Sun, 20 Nov 2011 13:00:00 +0100

We recognize Robert Louis Stevenson’s Long John Silver by his commanding presence, his stoicism and the absence of his left leg, cut off below the hip. Although we think we know the roguish Silver, characters such as he are not of this world, as Stevenson himself admitted in Longman’s Magazine in 1884. He described fictional characters as being like circles--abstractions. Scientists use circles to solve problems in physics, and writers and readers likewise use fictional characters to think about people in the social world.Psychologists once scoffed at fiction as a way of understanding people because--well--it’s made up. But in the past 25 years cognitive psychologists have developed a new appreciation for the significance of stories. Just as computer simulations have help...

A failing sense of smell can be reversed

EurekAlert! - Medicine and Health — Sun, 20 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) In a new study scientists at NYU Langone Medical Center have shown that the sense of smell can be improved. The new findings, published online Nov. 20, 2011, in Nature Neuroscience, suggest possible ways to reverse the loss of smell due to aging or disease. (Source: EurekAlert! - Medicine and Health)

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Botulinum Toxin-A (BoNT-A) in Trigeminal Neuralgia (TN): Outcome of Placebo-Controlled RCT

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 19 Nov 2011 09:05:18 +0100

This study was approved by the New York University institutional review board for human research. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Noncontrast Functional MRI of the Kidneys

Current Urology Reports — Fri, 18 Nov 2011 17:32:24 +0100

This article discusses the principles of these techniques, as well as their possible applications and limitations. This will introduce the readers to these novel imaging tools, which appear to have promising futures. Content Type Journal ArticleCategory New Techniques: Imaging (A Atala, Section Editor)Pages 1-9DOI 10.1007/s11934-011-0229-6Authors Lorenzo Mannelli, Department of Radiology, University of Washington, 1000 8th Avenue, Seattle, WA 98104, USAJeffrey H. Maki, Department of Radiology, University of Washington, 1000 8th Avenue, Seattle, WA 98104, USASherif F. Osman, Department of Radiology, University of Washington, 1000 8th Avenue, Seattle, WA 98104, USAHersh Chandarana, Department of Radiology, New York University, New York, NY, USADavid J. Lomas, Department of Radiology,...

Mild cognitive impairment: pathology and mechanisms

Acta Neuropathologica — Fri, 18 Nov 2011 17:28:27 +0100

Abstract Mild cognitive impairment (MCI) is rapidly becoming one of the most common clinical manifestations affecting the elderly. The pathologic and molecular substrate of people diagnosed with MCI is not well established. Since MCI is a human specific disorder and neither the clinical nor the neuropathological course appears to follow a direct linear path, it is imperative to characterize neuropathology changes in the brains of people who came to autopsy with a well-characterized clinical diagnosis of MCI. Herein, we discuss findings derived from clinical pathologic studies of autopsy cases who died with a clinical diagnosis of MCI. The heterogeneity of clinical MCI imparts significant challenges to any review of this subject. The pathologic substrate of MCI is equally c...

Targeting bacterial gas defenses allow for increased efficacy of numerous antibiotics

EurekAlert! - Medicine and Health — Thu, 17 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Although scientists have known for centuries that many bacteria produce hydrogen sulfide (H2S) it was thought to be simply a toxic by-product of cellular activity. Now, researchers at NYU School of Medicine have discovered H2S in fact plays a major role in protecting bacteria from the effects of numerous different antibiotics. (Source: EurekAlert! - Medicine and Health)

Researchers discover new way to form extracellular vesicles

EurekAlert! - Medicine and Health — Thu, 17 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Researchers at NYU Langone Medical Center have discovered a protein called TAT-5 that affects the production of extracellular vesicles, small sacs of membrane released from the surface of cells, capable of sending signals to other cells. (Source: EurekAlert! - Medicine and Health)

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Acamprosate modulates experimental autoimmune encephalomyelitis

Inflammopharmacology — Wed, 16 Nov 2011 16:45:51 +0100

Discussion Acamprosate and other taurine analogs have a potential for future MS therapy. Content Type Journal ArticleCategory Research ArticlePages 1-10DOI 10.1007/s10787-011-0097-1Authors Z. Sternberg, Department of Neurology, Baird MS Center, Jacobs Neurological Institute, 100 High Street, Buffalo, NY 14203, USAA. Cesario, Department of Neurology, Baird MS Center, Jacobs Neurological Institute, 100 High Street, Buffalo, NY 14203, USAK. Rittenhouse-Olson, Department of Biotechnical and Neurological Laboratory Sciences, University of Buffalo, 3435 Main Street, Buffalo, NY, USAR. A. Sobel, Department of Pathology, VA Health Care System, 3801 Miranda Avenue, Palo Alto, CA, USAO. Pankewycz, Department of Surgery, Buffalo General Hospital, State University of New York, Univ...

NYU Steinhardt professor receives to study insulin's role in obesity-related cancers

EurekAlert! - Medicine and Health — Wed, 16 Nov 2011 05:00:00 +0100

(New York University) Niyati Parekh, an assistant professor at New York University's Steinhardt School of Culture, Education, and Human Development, has received a $720,000 Research Scholar Grant from the American Cancer Society to study the role of insulin in obesity-related cancers. (Source: EurekAlert! - Medicine and Health)

Rusk experts present at American Association of Physical Medicine and Rehabilitation meeting

EurekAlert! - Social and Behavioral Science — Wed, 16 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Experts from Rusk Institute of Rehabilitation Medicine at NYU Langone Medical Center will present research and clinical insight into complex medical rehabilitation, the treatment of traumatic brain injuries and the integration of handheld technologies into practice management at the American Association of Physical Medicine and Rehabilitation (AAPM&R) Annual Meeting in Orlando, Nov. 17-20, 2011. (Source: EurekAlert! - Social and Behavioral Science)

The Machine That Would Predict the Future (preview)

Scientific American - Official RSS Feed — Tue, 15 Nov 2011 16:31:00 +0100

In the summer and fall of last year, the Greek financial crisis tore at the seams of the global economy. Having run up a debt that it would never be able to repay, the country faced a number of potential outcomes, all unpleasant. Efforts to slash spending spurred riots in the streets of Athens, while threats of default rattled global financial markets. Many economists argued that Greece should leave the euro zone and devalue its currency, a move that would in theory help the economy grow. “Make no mistake: an orderly euro exit will be hard,” wrote New York University economist Nouriel Roubini in the Financial Times . “But watching the slow disorderly implosion of the Greek economy and society will be much worse.”No one was sure exactly how the scenario would play ou...

NYUs Jian Li wins Gruber International Research Award from Society of Neuroscience

EurekAlert! - Social and Behavioral Science — Mon, 14 Nov 2011 05:00:00 +0100

(New York University) Jian Li, a postdoctoral fellow at New York University, has been awarded the Peter and Patricia Gruber International Research Award in Neuroscience. (Source: EurekAlert! - Social and Behavioral Science)

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The mathematical law that shows why wealth flows to the 1%

Guardian Unlimited Science — Fri, 11 Nov 2011 19:29:00 +0100

No one who is interested in an equitable society can fail to be irked by unfairness in wealth distribution – but it is not unexpectedOne of the main issues raised by the Occupy demonstrators is the inequitable distribution of wealth. Their slogan focuses on the extreme difference between the richest and the poorest: "We are the 99%," say the banners and T-shirts, pointing out that 1% of the world's population has somehow clawed its way to disproportionate money and power. Time to do something about this unnatural distribution, no?The economist Edward N Wolff, of New York University, has pointed out that, as of 2007, the top 1% of households in America owned 34.6% of all privately held wealth, and the next 19% had 50.5% of the wealth. This means that just 20% of the people ...

Stress from Poverty Affects Kids’ Grades

Psychology Today Parenting Center — Fri, 11 Nov 2011 15:30:21 +0100

Poverty is a serious condition that afflicts millions of people around the world. Particularly distressing is when poverty affects the lives of children. Poverty can cause hunger, poor living conditions, and the need for children to work at an earlier age. Additionally, a recent study conducted by researchers at Penn State University, New York University, and Chapel Hill found Primary Topic: Stress read more (Source: Psychology Today Parenting Center)

NYU Langone experts present at Society for Neuroscience Annual Meeting

EurekAlert! - Social and Behavioral Science — Fri, 11 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Experts from the Neuroscience Institute at NYU Langone Medical Center will present new research and participate in panel discussions at the Society for Neuroscience 41st Annual Meeting in Washington, DC, Nov. 12-16, 2011. (Source: EurekAlert! - Social and Behavioral Science)

Improved Understanding Of Fertility In Female Fruit Flies Has Implications For Fighting Disease Transmitting Insects

Health News from Medical News Today — Thu, 10 Nov 2011 08:00:00 +0100

A team of New York University biologists has uncovered a previously unknown role for a set of cells within the female reproductive tract of fruit flies that affects the functioning of sperm and hence fertility. Their discovery, which is published in the online, open-access journal PloS Biology, adds to our understanding of how insects reproduce and may provide a means to manipulate reproductive behaviour in other insects... (Source: Health News from Medical News Today)

NYU Langone expert calls for awareness, research of sudden death in patients with epilepsy

EurekAlert! - Social and Behavioral Science — Thu, 10 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Over time, epileptic seizures can lead to major health issues, including significant cognitive decline and even death, warns Orrin Devinsky, M.D., professor, Departments of Neurology, Neurosurgery and Psychiatry at NYU Langone Medical Center. (Source: EurekAlert! - Social and Behavioral Science)

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Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma

Investigational New Drugs — Wed, 09 Nov 2011 17:56:19 +0100

Conclusion KOS-862 was well tolerated with manageable toxicity, favorable PK profile, and the suggestion of clinical activity. The maximum tolerated dose was determined to be 100 mg/m2 weekly 3-on/1-off. MTBF can be demonstrated in PBMCs of patients exposed to KOS-862. Content Type Journal ArticleCategory PHASE I STUDIESPages 1-9DOI 10.1007/s10637-011-9765-7Authors Jason Konner, Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USARachel N. Grisham, Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USAJae Park, Gynecologic Medical Oncology Service, Department of Medicine, Memorial Sloan-Kettering Can...

Intentional partial coiling dome protection of complex ruptured cerebral aneurysms prevents acute rebleeding and produces favorable clinical outcomes

Acta Neurochirurgica — Wed, 09 Nov 2011 07:01:33 +0100

Conclusions Judicious use of a treatment strategy of intentional partial dome protection for complex aneurysms that are not favorable for clipping and in which complete coiling primarily is not possible may prevent acute rebleeding and produce favorable clinical outcomes. Content Type Journal ArticleCategory Clinical ArticlePages 1-5DOI 10.1007/s00701-011-1214-zAuthors Ben Waldau, Department of Neurosurgery, University of Florida, Gainesville, FL, USAJohn F. Reavey-Cantwell, Department of Neurosurgery, Virginia Commonwealth University, Richmond, VA, USAMatthew F. Lawson, Department of Neurosurgery, University of Florida, Gainesville, FL, USAShady Jahshan, Department of Neurosurgery, University at Buffalo, State University of New York, Buffalo, NY, USAElad I. Levy, D...

Steven B. Abramson, MD, receives distinguished Basic Investigator Award at ACR 2011

EurekAlert! - Medicine and Health — Mon, 07 Nov 2011 05:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Steven B. Abramson, MD, senior vice president and vice dean of education, faculty and academic affairs and professor, Departments of Medicine and Pathology at NYU Langone Medical Center received the Distinguished Basic Investigator Award at the American College of Rheumatology & Association of Rheumatology Health Professionals annual scientific meeting this week in Chicago. (Source: EurekAlert! - Medicine and Health)

Erratum to: Association of the ZFPM2 gene with antipsychotic-induced parkinsonism in schizophrenia patients

Psychopharmacology — Sat, 05 Nov 2011 15:44:39 +0100

Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s00213-011-2547-2Authors Lior Greenbaum, Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–Hebrew University Medical Center, Ein Karem, Jerusalem, 91120 IsraelRobert C. Smith, Department of Psychiatry, New York University Medical School, New York, NY, USAMordechai Lorberboym, Department of Nuclear Medicine, Edith Wolfson Medical Center, Holon, IsraelAnna Alkelai, Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–Hebrew University Medical Center, Ein Karem, Jerusalem, 91120 IsraelPolina Zozulinsky, Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–Hebrew University Medical Center, Ein Karem, Jerusalem, 91120 IsraelTzuri Lifschytz, Biological Psychiatry Laborato...

RAGE Gene Deletion Inhibits the Development and Progression of Ductal Neoplasia and Prolongs Survival in a Murine Model of Pancreatic Cancer

Journal of Gastrointestinal Surgery — Fri, 04 Nov 2011 05:44:01 +0100

Conclusion Loss of RAGE function inhibited the development of PanIN and progression to PDAC and significantly prolonged survival in these mouse models. Further work is needed to target the ligand–RAGE axis for possible early intervention and prophylaxis in patients at risk for developing pancreatic cancer. Content Type Journal ArticleCategory 2011 SSAT Plenary PresentationPages 1-9DOI 10.1007/s11605-011-1754-9Authors Joseph DiNorcia, College of Physicians and Surgeons, Department of Surgery, Columbia University, 161 Fort Washington Avenue, Suite 820, New York, NY 10032-3784, USAMinna K. Lee, College of Physicians and Surgeons, Department of Surgery, Columbia University, 161 Fort Washington Avenue, Suite 820, New York, NY 10032-3784, USADorota N. Moroziewicz, Colle...

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NYU Langone experts present at American College of Rheumatology 2011 Annual Meeting

EurekAlert! - Social and Behavioral Science — Fri, 04 Nov 2011 04:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Experts from NYU Langone Medical Center will present new research findings and clinical insight into the treatment of rheumatic and bone diseases in a variety of presentations at the American College of Rheumatology 2011 Annual Scientific Meeting in Chicago, Nov. 5-9, 2011. (Source: EurekAlert! - Social and Behavioral Science)

New study from NYUCN is the first to look at nursing error disclosure in nursing homes

EurekAlert! - Social and Behavioral Science — Fri, 04 Nov 2011 04:00:00 +0100

(New York University) In the study, "Nurses' Perceptions of Error Reporting and Disclosure in Nursing Homes," published in the January 2012 issue of the Journal of Nursing Care Quality, the authors found the majority of registered nurse respondents reported error disclosure and responding to be a difficult process in their workplaces. The study has implications to improve nursing education, policy, and patient safety culture in the nursing home setting. (Source: EurekAlert! - Social and Behavioral Science)

NYUCD awarded $2.2 million NIH grant to decode genome of caries-causing bacteria

EurekAlert! - Medicine and Health — Thu, 03 Nov 2011 04:00:00 +0100

(New York University) The recent development of whole genome sequencing has made it much easier to identify destructive bacteria. Now, an New York University dental research team has received a four-year, $2.2 million dollar grant from the National Institute of Dental and Craniofacial Research, part of the National Institutes of Health, to use whole genome sequencing to identify those strains of Lb that contribute to the development of severe early childhood caries. (Source: EurekAlert! - Medicine and Health)

FDA Approves Melafind For Detecting Skin Cancer And Melanoma

Health News from Medical News Today — Wed, 02 Nov 2011 19:00:00 +0100

Good news for anyone worried about skin cancer with the FDA approving Melafind, which the manufacturers describe as a groundbreaking technology for detecting melanomas. Darrell S. Rigel, MD, Clinical Professor of Dermatology at New York University Medical School confirmed the news : "MelaFind is a groundbreaking technology and represents one of the most significant advances in early melanoma detection since the advent of the ABCD criteria that our group developed over a quarter century ago ... (Source: Health News from Medical News Today)

The Orthostatic Hypotension Questionnaire (OHQ): validation of a novel symptom assessment scale

Clinical Autonomic Research — Tue, 01 Nov 2011 16:51:51 +0100

Conclusion These findings provide empirical evidence that the OHQ can accurately evaluate the severity of symptoms and the functional impact of NOH as well as assess the efficacy of treatment. Content Type Journal ArticleCategory Research ArticlePages 1-12DOI 10.1007/s10286-011-0146-2Authors Horacio Kaufmann, Department of Neurology, New York University School of Medicine, New York, NY, USARichard Malamut, Neuroscience Therapeutic Area, Clinical Development, AstraZeneca, Wilmington, DE, USALucy Norcliffe-Kaufmann, Department of Neurology, New York University School of Medicine, New York, NY, USAKathleen Rosa, Clinical Research Program, School of Nursing, University of North Carolina Wilmington, Wilmington, NC, USARoy Freeman, Center for Autonomic and Peripheral Nerve...

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Health Care Reform and the Primary Care Workforce Bottleneck

Journal of General Internal Medicine — Tue, 01 Nov 2011 05:53:38 +0100

Abstract To establish and sustain the high-performing health care system envisioned in the Affordable Care Act (ACA), current provisions in the law to strengthen the primary care workforce must be funded, implemented, and tested. However, the United States is heading towards a severe primary care workforce bottleneck due to ballooning demand and vanishing supply. Demand will be fueled by the “silver tsunami” of 80 million Americans retiring over the next 20 years and the expanded insurance coverage for 32 million Americans in the ACA. The primary care workforce is declining because of decreased production and accelerated attrition. To mitigate the looming primary care bottleneck, even bolder policies will be needed to attract, train, and sustain a sufficient numbe...

NYUCN receives $994,000 HRSA grant to research increasing nursing faculty diversity

EurekAlert! - Medicine and Health — Tue, 01 Nov 2011 04:00:00 +0100

(New York University) New York University College of Nursing received a three-year, $994,741 grant from the Human Resources & Services Administration to research "Nursing Education Masters and Post Masters Certificate Program Enhancement." The project's overall purpose is to increase the number, diversity, and competencies of graduates of the NYUCN Nursing Education MS and post-MS Certificate Programs who will be available to teach diverse nursing students and graduate culturally competent RNs. (Source: EurekAlert! - Medicine and Health)

NYUCN receives $994,000 HRSA grant to research increasing nursing faculty diversity and the use of simulation

EurekAlert! - Medicine and Health — Tue, 01 Nov 2011 04:00:00 +0100

Editorial Comment

Urology — Tue, 01 Nov 2011 04:00:00 +0100

Since its original description, high-grade prostatic intraepithelial neoplasia (HGPIN) as a finding on prostate biopsy specimens has been the source of ongoing confusion. The original reports of high rates of cancer detection on repeat biopsy corresponded to sextant biopsies and undersampling of disease. With extended biopsies, the studies from New York University (NYU) found only a single case of prostate cancer in men who underwent relatively immediate biopsy, thus advocating no role for immediate repeat biopsy solely on the indication of HGPIN alone. (Source: Urology)

Combination of activated Schwann cells with bone mesenchymal stem cells: the best cell strategy for repair after spinal cord injury in rats.

Regenerative Medicine — Tue, 01 Nov 2011 04:00:00 +0100

Conclusion: Effective co-transplantation of ASCs and BMSCs promotes functional recovery in rats' hindlimbs and reduces the formation of glial scar, and remyelinates the injured axons as compared with the other three groups. This conclusion was also supported by the observation of immunohistochemistry staining and electron microscopy, suggesting the possible clinical application for the treatment of spinal injury. PMID: 22050523 [PubMed - in process] (Source: Regenerative Medicine)

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Neurologists identify potential biomarker of cognitive decline for earlier diagnosis of disease

EurekAlert! - Social and Behavioral Science — Mon, 31 Oct 2011 04:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Researchers from the Department of Neurology at NYU Langone Medical Center identified for the first time that changes in the tissue located at the junction between the outer and inner layers of the brain, called "blurring", may be an important, non-invasive biomarker for earlier diagnosis and the development of new therapies for degenerative brain conditions, such as multiple sclerosis. The study was published in the Oct. 26th issue of the Journal of Neuroscience. (Source: EurekAlert! - Social and Behavioral Science)

Poverty-Related Stress Affects Readiness For School

Health News from Medical News Today — Sun, 30 Oct 2011 07:00:00 +0100

Stress in the lives of poor children is one cause of the early achievement gap in which children from low-income homes start school behind their more advantaged classmates. That's the finding from a new study by scientists at Pennsylvania State University, New York University, and the University of North Carolina at Chapel Hill. The study appears in the journal Child Development... (Source: Health News from Medical News Today)

Diet and the risk of head and neck cancer: a pooled analysis in the INHANCE consortium

Cancer Causes and Control — Fri, 28 Oct 2011 17:13:14 +0100

Abstract We investigated the association between diet and head and neck cancer (HNC) risk using data from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. The INHANCE pooled data included 22 case–control studies with 14,520 cases and 22,737 controls. Center-specific quartiles among the controls were used for food groups, and frequencies per week were used for single food items. A dietary pattern score combining high fruit and vegetable intake and low red meat intake was created. Odds ratios (OR) and 95% confidence intervals (CI) for the dietary items on the risk of HNC were estimated with a two-stage random-effects logistic regression model. An inverse association was observed for higher-frequency intake of fruit (4th vs. 1st quartile OR =&n...

Clinical relevance of blast-related traumatic brain injury

Acta Neurochirurgica — Fri, 28 Oct 2011 16:44:21 +0100

Content Type Journal ArticleCategory EditorialPages 1-4DOI 10.1007/s00701-011-1210-3Authors Geoffrey Appelboom, Department of Neurological Surgery, The Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USAJames Han, Department of Neurological Surgery, The Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USASam Bruce, Department of Neurological Surgery, The Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USACaroline Szpalski, Department of Plastic and Craniofacial Surgery, New York University (NYU), New York, NY 10016, USAE. Sander Connolly, Department of Neurological Surgery, The Neurological Institute, Columbia University College of P...

NYUCN receives $7.56 million NIH grant to research heterosexuals at high risk of HIV infection

EurekAlert! - Social and Behavioral Science — Fri, 28 Oct 2011 04:00:00 +0100

(New York University) New York University College of Nursing received a five-year, $7.56 million grant from the National Institute on Drug Abuse at the National Institutes of Health to evaluate the efficacy and cost-effectiveness of a peer-driven intervention to seek out heterosexuals at high risk for HIV in their communities, test them for HIV, and link them to care in a timely fashion if they are found to be HIV infected. (Source: EurekAlert! - Social and Behavioral Science)

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NYUCN receives $1 million HRSA grant to incorporate primary care into nurse-midwives' education

EurekAlert! - Social and Behavioral Science — Fri, 28 Oct 2011 04:00:00 +0100

(New York University) New York University College of Nursing received a three-year, $1,002,318.00 grant from the Human Resources & Services Administration to research "Midwifery: Primary Care and Health Literacy Program Enhancement." Principal investigator Ann Kurth notes that nurse-midwives state the largest barrier to incorporating primary care into practice is the lack of experience in clinical primary care during training. (Source: EurekAlert! - Social and Behavioral Science)

NYUCN receives $4.2 million NIH/NIDA grant to study injecting drug users in Kenya

EurekAlert! - Social and Behavioral Science — Fri, 28 Oct 2011 04:00:00 +0100

(New York University) New York University College of Nursing received a five-year, $4,161,665.00 grant from the National Institute of Health's National Institute on Drug Abuse to research "Test and Linkage to Care Among Injecting Drug Users (TLC_IDU) Kenya." Principal investigator Ann Kurth notes HIV infections in sub-Saharan Africa increasingly occur among injecting drug users, a most-at-risk population. (Source: EurekAlert! - Social and Behavioral Science)

NYUCN receives $2.8 million NIH/NIAID grant to study combination HIV prevention for Kenyan youth

EurekAlert! - Medicine and Health — Fri, 28 Oct 2011 04:00:00 +0100

(New York University) New York University College of Nursing received a four-year, $ 2.8 million grant from the National Institute of Health's National Institute of Allergy and Infectious Diseases to study "Combination HIV Prevention for Kenyan Youth." The grant is a collaboration between NYUCN, the University of Nairobi, and Impact-RDO, a nongovernmental organization in western Kenya. (Source: EurekAlert! - Medicine and Health)

University of Minnesota study uncovers clues to young children's aggressive behavior

EurekAlert! - Social and Behavioral Science — Thu, 27 Oct 2011 04:00:00 +0100

(New York University) Children who are persistently aggressive, defiant, and explosive by the time they're in kindergarten very often have tumultuous relationships with their parents from early on. A new longitudinal study suggests that a cycle involving parenting styles and hostility between mothers and toddlers is at play. (Source: EurekAlert! - Social and Behavioral Science)

NYU College of Nursing receives 450 thousand dollar NIH grant to research post-breast cancer lymphedema

EurekAlert! - Medicine and Health — Thu, 27 Oct 2011 04:00:00 +0100

(New York University) New York University College of Nursing received a two-year, $452,218.00 grant from the national Institutes of Health to research ""Proinflammatory Biomarkers and Post-Breast Cancer Lymphedema." Post-breast cancer lymphedema, a syndrome of abnormal swelling and multiple distressing symptoms, is caused by injuries to the lymphatic system from cancer treatment. As advances in cancer treatment lengthen survival, LE has emerged as a high-impact long-term morbidity that profoundly impairs survivors' quality of life. (Source: EurekAlert! - Medicine and Health)

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NYUCN receives $299 thousand from NCSBN to study patient safety in nursing homes

EurekAlert! - Medicine and Health — Thu, 27 Oct 2011 04:00:00 +0100

(New York University) New York University College of Nursingreceived a two-year, $299,990.00 grant from the National Council of State Boards of Nursing Grant (NCSBN) to research the "Impact of an Internationally Educated Nurse Workforce on Patient Safety Processes and Outcomes in Nursing Homes." According to the Principal Investigator, Laura Wagner, the purpose of the study is to meet the NCSBN's Patient Safety, Practice, and International Regulatory Issues Research Priorities. (Source: EurekAlert! - Medicine and Health)

Biologists Describe Key Mechanism In Early Embryo Development

Health News from Medical News Today — Mon, 24 Oct 2011 07:00:00 +0100

New York University and University of Iowa biologists have identified a key mechanism controlling early embryonic development that is critical in determining how structures such as appendages - arms and legs in humans - grow in the right place and at the right time. In a paper published in the journal PLoS Genetics, John Manak, an assistant professor of biology in the UI College of Liberal Arts and Sciences, and Chris Rushlow, a professor in NYU's Department of Biology, write that much research has focused on the spatial regulatory networks that control early developmental processes... (Source: Health News from Medical News Today)

The Microbiome And Its Possible Role In Cancers

Health News from Medical News Today — Mon, 24 Oct 2011 07:00:00 +0100

In the journal Cell Host and Microbe, Drs. Claudia Plottel and Martin J. Blaser of the Departments of Medicine and Microbiology at NYU Langone Medical Center, and the Department of Biology at New York University, present a model for understanding how cancer evolves in humans based on an understanding of the bacteria living in our body, the microbiome. The authors suggest that the bacteria that reside in us play a crucial role in maintaining our health. This starts early in our lives, when a newborn is "seeded" with bacteria in the birth canal... (Source: Health News from Medical News Today)

More or LESS

Techniques in Coloproctology — Fri, 21 Oct 2011 05:46:48 +0100

Content Type Journal ArticleCategory Invited CommentPages 1-2DOI 10.1007/s10151-011-0778-1Authors R. Bergamaschi, Division of Colon & Rectal Surgery, State University of New York, Stony Brook, NY, USA Journal Techniques in ColoproctologyOnline ISSN 1128-045XPrint ISSN 1123-6337 (Source: Techniques in Coloproctology)

Preventing cancer development inside the cell cycle

EurekAlert! - Medicine and Health — Fri, 21 Oct 2011 04:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Researchers from the NYU Cancer Institute, an NCI-designated cancer center at NYU Langone Medical Center, have identified a cell cycle-regulated mechanism behind the transformation of normal cells into cancerous cells. The study results suggest that inhibition of the CK1 enzyme may be a new therapeutic target for the treatment of cancer cells formed as a result of a malfunction in the cell's mTOR signaling pathway. (Source: EurekAlert! - Medicine and Health)

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N.Y.C. Hospital Groups, Continuum and NYU, May Ally

NYT Health — Fri, 21 Oct 2011 03:20:08 +0100

A proposed alliance between Continuum Health Partners and NYU Langone Medical Center reflects a wider trend toward bigger medical organizations. (Source: NYT Health)

ARL (Association of Research Libraries) announces 2011-2012 Board of Directors

News from STM — Thu, 20 Oct 2011 19:44:16 +0100

The Association of Research Libraries (ARL) announced on October 20 its 2011-2012 board of directors. Winston Tabb, Sheridan Dean of University Libraries and Museums, Johns Hopkins University, began a one-year term as president of ARL on October 13, 2011, during the ARL Membership Meeting in Washington, DC. He succeeds Carol A. Mandel, Dean of the Division of Libraries, New York University. Mandel continues to serve as a member of both the ARL Board of Directors and the ARL Executive Committee as Past President. http://bit.ly/nF8qhG (Source: News from STM)

Does a preoperative medically supervised weight loss program improve bariatric surgery outcomes? A pilot randomized study

Surgical Endoscopy — Thu, 20 Oct 2011 05:56:08 +0100

Conclusion MSWM does not appear to confer additional benefit as compared to the standard preoperative bariatric surgery protocol in terms of weight loss and most behavioral outcomes after LAGB in our patient population. Content Type Journal ArticlePages 1-9DOI 10.1007/s00464-011-1966-9Authors Manish Parikh, Bellevue Center for Obesity and Weight Management, Bellevue Hospital Center, Department of Surgery, New York University School of Medicine, New Bellevue 15 South 7, 550 First Avenue, New York, NY 10016, USAMeena Dasari, Bellevue Center for Obesity and Weight Management, Bellevue Hospital Center, Department of Surgery, New York University School of Medicine, New Bellevue 15 South 7, 550 First Avenue, New York, NY 10016, USAMichelle McMacken, Department of Medicine,...

Novel therapeutic target identified to decrease triglycerides and increase 'good' cholesterol

EurekAlert! - Medicine and Health — Thu, 20 Oct 2011 04:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) Researchers at NYU Langone Medical Center today announce findings published in the Oct. 20 issue of Nature that show for the first time the inhibition of both microRNA-33a and microRNA-33b with chemically modified anti-miR oligonucleotides markedly suppress triglyceride levels and cause a sustained increase in high density lipoprotein cholesterol "good" cholesterol. (Source: EurekAlert! - Medicine and Health)

Researchers at NYU Langone Medical Center review the microbiome and its possible role in cancers

EurekAlert! - Medicine and Health — Thu, 20 Oct 2011 04:00:00 +0100

(NYU Langone Medical Center / New York University School of Medicine) In the Oct. 20 edition of the journal Cell Host and Microbe, Drs. Claudia Plottel and Martin J. Blaser of the Departments of Medicine and Microbiology at NYU Langone Medical Center, and the Department of Biology at New York University, present a model for understanding how cancer evolves in humans based on an understanding of the bacteria living in our body, the microbiome. (Source: EurekAlert! - Medicine and Health)

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SUNY receives $4.3 million for research in neuroscience, pediatric pharmacology and vision

EurekAlert! - Medicine and Health — Fri, 14 Oct 2011 04:00:00 +0100

(SUNY Downstate Medical Center) The State University of New York has received two grants totaling more than $4.3 million from the National Institutes of Health (NIH) to support neuroscience and pediatric pharmacology and vision research as part of SUNY REACH, a collaborative research network of SUNY's four academic health centers and the College of Optometry. The lead researchers on both grants will be headquartered at SUNY Downstate Medical Center in Brooklyn, New York. (Source: EurekAlert! - Medicine and Health)

Description of children with 45,X/46,XY karyotype

European Journal of Pediatrics — Thu, 13 Oct 2011 15:48:39 +0100

In conclusion, these children require clinical evaluation similar to that performed in female children with TS, including cardiovascular, renal, endocrine, growth and development, autoimmune, psychological, and educational evaluation. Specific management needs to be tailored to the presence of Y chromosomal material. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00431-011-1600-9Authors Hanan Tosson, Pediatric Endocrinology Clinic, Morgantown, WV, USASusan R. Rose, Division of Pediatric Endocrinology, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center and University of Cincinnati, Cincinnati, OH, USALou Ann Gartner, Division of Pediatric Endocrinology, Department of Pediatrics, Women’s and Children’s Hospital of Buffalo and Stat...

Clinical evaluation of a novel method for the measurement of prostate‐specific antigen, AccuPSATM, as a predictor of 5‐year biochemical recurrence‐free survival after radical prostatectomy: results of a pilot study

BJU International — Wed, 12 Oct 2011 04:00:00 +0100

CONCLUSIONS• AccuPSATM assay predicts 5‐year BCR‐ free survival after RP.• Identifying a reliable predictor of BCR soon after RP has important implications for frequency of PSA testing, selection of candidates for adjuvant therapy, and reassuring a large subset of men that they are not at risk of recurrence.• Larger studies are needed to validate these findings. (Source: BJU International)

$2.8M Grant to Fund LGBT Youth Suicide Risk Study

Health — Tue, 11 Oct 2011 07:00:00 +0100

Researchers at the UA and New York University will study the causes behind suicide risk for lesbian, gay, bisexual and transgender youth over a three-year period thanks to a $2.8 million grant from the National Institute of Mental Health. (Source: Health)

Thomas Sargent and Christopher Sims win Nobel prize for economics

Guardian Unlimited Science — Mon, 10 Oct 2011 18:39:40 +0100

US academics praised for work modelling the impact of central bank and government policies on macro-economic growthTwo US academics have won the Nobel prize for economics for their work modelling the impact of central bank and government policies on macro-economic growth.Thomas Sargent and Christopher Sims will receive 10m kroner (£1m) for helping policymakers understand expectations of economic policy changes and how the changes themselves interact with each other and influence the path of policymaking.Prof Sargent, who works at New York University, has pursued similar research to Prof Sims, who is a professor at Princeton University, which the Nobel committee said was complementary.Sims told a press conference after the award was announced: "I have been telling people I wouldn't be gett...

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Physicians treating Latinos have high hurdles to jump, study shows

UCLA Newsroom: Health Sciences — Mon, 10 Oct 2011 16:45:00 +0100

Experts have written about health care disparities between Latinos and non-Latino whites, mostly from a policy standpoint. They've also looked at the same disparities from the perspective of the patient, in terms of access, use and the quality of health care. But how do the physicians feel about the quality of care they provide? What challenges do doctors face in treating Latino patients, compared with physicians whose patients are primarily white and non-Latino? Research out of UCLA and the City University of New York has found that primary care physicians who treat Latinos are less likely than physicians treating primarily white patients to believe they can provide high-quality care. Among the reasons: inadequate time with patients, patients' lack of ability to afford care,...

Biologists Study Color Detection In The Eye

Health News from Medical News Today — Mon, 10 Oct 2011 09:00:00 +0100

New York University biologists have identified a new mechanism for regulating color vision by studying a mutant fly named after Frank ('Ol Blue Eyes) Sinatra. Their findings, which appear in the journal Nature, focus on how the visual system functions in order to preserve the fidelity of color discrimination throughout the life of an organism. They also offer new insights into how genes controlling color detection are turned on and off. Many biologists study how different cells develop to acquire their fate... (Source: Health News from Medical News Today)

High cortisol levels are associated with low quality food choice in type 2 diabetes

Endocrine — Sun, 09 Oct 2011 05:36:38 +0100

Abstract Hypothalamic–pituitary–adrenal (HPA) axis control may be impaired in type 2 diabetes (T2DM). Glucocorticoids increase consumption of low quality foods high in calories, sugar, and fat. We explored the relationship between cortisol levels, poor blood glucose control, and food quality choice in T2DM. Twenty-seven healthy controls were age-, gender- and education-matched to 27 T2DM participants. Standard clinical blood tests and cortisol values were measured from fasting blood samples. Participants recorded all consumed food and drink items in a consecutive 3-day food diary. Diaries were analyzed for “high quality” and “low quality” foods using a standardized method with high reliability (0.97 and 0.86, respectively). Controlling for education, body mass ...

NYU biologists use Sinatra-named fly to show how to see the blues -- and the greens

EurekAlert! - Biology — Sun, 09 Oct 2011 04:00:00 +0100

(New York University) NYU biologists have identified a new mechanism for regulating color vision by studying a mutant fly named after Frank ('Ol Blue Eyes) Sinatra. Their findings focus on how the visual system functions in order to preserve the fidelity of color discrimination throughout the life of an organism. They also offer new insights into how genes controlling color detection are turned on and off. (Source: EurekAlert! - Biology)

Estimating HIV Incidence and the Correlates of Recent Infection in Venue-Sampled Men Who Have Sex With Men in New York City

AIDS and Behavior — Fri, 07 Oct 2011 15:57:18 +0100

Abstract In a cross-sectional study, MSM aged ≥18 years were venue-sampled in New York City in 2008, interviewed, and tested for HIV using oral fluids. Participants who reported testing HIV negative at their last test in the previous 24 months were analyzed (n = 287 of 550 sampled). Those testing positive at the interview were defined as recently infected. HIV incidence was estimated using person-time at-risk methods and correlates of recent infection using proportional hazards regression. Thirty-two (11.1%) were recently infected. HIV incidence was 5.67/100 person-years at-risk. Independent correlates included: study recruitment in parks vs. bars, and in other venues vs. bars; black vs. non-black race/ethnicity; and reporting a last sex partner with ...

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Tension-Type Headache Mimics

Current Pain and Headache Reports — Thu, 06 Oct 2011 05:48:29 +0100

Abstract Tension-type headache (TTH) is a relatively featureless headache. Many primary and secondary headache disorders can mimic TTH, particularly in its chronic form, chronic tension-type headache. This review will address both primary and secondary disorders that can present with headaches phenotypically similar to TTH, and will focus on clinical pearls that help distinguish these “mimics” from TTH. Content Type Journal ArticleCategory Tension-type Headache (Katherine Henry, Section editor)Pages 1-8DOI 10.1007/s11916-011-0226-yAuthors Sara C. Crystal, Department of Neurology, New York University School of Medicine, 462 First Avenue, Suite NBV 7W11, New York, NY 10016, USAMatthew S. Robbins, The Montefiore Headache Center, Saul R. Korey Department of Neurology, ...

Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice

Cancer Chemotherapy and Pharmacology — Tue, 04 Oct 2011 05:50:34 +0100

Conclusion This oral absorption enhanced NEC may provide a practical formulation to conduct the correlative study of the PK of curcuminoids and their pharmacodynamics, e.g., hypomethylation activity in vivo. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00280-011-1749-yAuthors Liu Zhongfa, College of Pharmacy, The Ohio State University, Room 152, Riffe Building, 500 W. 12th Avenue, Columbus, OH 43210, USAMing Chiu, College of Pharmacy, The Ohio State University, Room 152, Riffe Building, 500 W. 12th Avenue, Columbus, OH 43210, USAJiang Wang, College of Pharmacy, The Ohio State University, Room 152, Riffe Building, 500 W. 12th Avenue, Columbus, OH 43210, USAWei Chen, College of Pharmacy, The Ohio State University, Room 152, Riffe Building...

Me, myself, and I: the rise of the modern self

Annals of the New York Academy of Sciences — Sat, 01 Oct 2011 04:00:00 +0100

Moderated by Robert Hanna (University of Colorado), historians Gerald Izenberg (Washington University, St. Louis) and Jerrold Seigel (New York University), philosopher Raymond Martin (University of Maryland and Union College), and sociologist Norbert Wiley (University of Illinois) trace the evolution of the meaning of self from antiquity to the present and consider how the self described by classical philosophers matches the reality of what we know about ourselves from human experience and research. (Source: Annals of the New York Academy of Sciences)

Anna Motz (ed.): Managing Self-Harm: Psychological Perspectives

Clinical Social Work Journal — Tue, 27 Sep 2011 05:42:57 +0100

Content Type Journal ArticleCategory Book ReviewPages 1-3DOI 10.1007/s10615-011-0365-yAuthors Michelle R. Munson, New York University, 1 Washington Square North, New York, NY 10003, USA Journal Clinical Social Work JournalOnline ISSN 1573-3343Print ISSN 0091-1674 (Source: Clinical Social Work Journal)

Music for surgery

Guardian Unlimited Science — Mon, 26 Sep 2011 19:30:02 +0100

Surgeons who listen to music while they work are more relaxed and better at their jobs, according to a new survey. But which is best – Beethoven, the Black Eyed Peas or Black Sabbath?It was, says Charlie, a friend, "one of the stranger moments in my life". The middle of the night, an operating theatre in a hospital in east London, towards the end of a difficult and stressful delivery. This was Charlie and his partner's first baby, a boy, his umbilical cord was wrapped around him, and it was a tense moment for everyone."So there we were," says Charlie, "wheeled in for a caesarian. I was next to my partner, who was well dosed with anaesthetic, doing my best to comfort her. And someone says, 'What shall we have tonight, then?' and puts on some thumping house music. It was 3am and to be hone...

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NYU’s SOLVE Receives Multi-Million Dollar HIV Grant

PRWeb: Medical Pharmaceuticals — Mon, 26 Sep 2011 11:06:21 +0100

New York University School of Medicine’s Section on Value and Effectiveness (SOLVE) and Yale Schools of Medicine and Public Health have received a five-year grant for HIV and alcoholism research.(PRWeb September 24, 2011)Read the full story at http://www.prweb.com/releases/2011/9/prweb8822394.htm (Source: PRWeb: Medical Pharmaceuticals)

The utility of fetal echocardiography after an unremarkable anatomy scan.

Obstetrics and Gynecology — Sun, 25 Sep 2011 18:48:43 +0100

CONCLUSION: : In a tertiary care center with operators performing a high volume of ultrasound screenings, fetal echocardiography after normal anatomy ultrasound scan may be of limited benefit. LEVEL OF EVIDENCE: : III. PMID: 21934457 [PubMed - in process] (Source: Obstetrics and Gynecology)

Association of the ZFPM2 gene with antipsychotic-induced parkinsonism in schizophrenia patients

Psychopharmacology — Fri, 23 Sep 2011 15:46:05 +0100

Conclusions Our preliminary findings support association of the ZFPM2 SNP, rs12678719, with AIP. At the functional level, this variant is associated with deficits in the nigrostriatal pathway in PD patients that may be related to latent subclinical deficits among AIP-prone individuals with schizophrenia. Further validation studies in additional populations are required. Content Type Journal ArticleCategory Original InvestigationPages 1-10DOI 10.1007/s00213-011-2499-6Authors Lior Greenbaum, Biological Psychiatry Laboratory, Department of Psychiatry, Hadassah–Hebrew University Medical Center, Ein Karem, Jerusalem, 91120 IsraelRobert C. Smith, Department of Psychiatry, New York University Medical School, New York, NY, USAMordechai Lorberboym, Department of Nuclear Me...

Management of the Failed Transurethral Resection of the Prostate

Current Bladder Dysfunction Reports — Fri, 23 Sep 2011 05:45:14 +0100

Abstract Transurethral resection of the prostate (TURP) is the gold standard for treatment of symptomatic benign prostatic enlargement. Failure of TURP and other similar procedures may occur when a patient has poor bladder emptying postoperatively or has persistent or de novo bothersome postoperative lower urinary tract symptoms. Reasons for failure include inadequate resection, clot retention, anesthesia-related side effects, postoperative pain, hypo- or acontractile bladder, and/or poor patient selection. Patients initially can be managed conservatively or proactively. When clinically significant storage or voiding dysfunction persists, evaluation is necessary and may include cystoscopy and/or urodynamics. Depending on the diagnosis and etiology, patients can then be man...

NYU study finds congestion pricing works best when partnered with land-use planning

EurekAlert! - Social and Behavioral Science — Fri, 23 Sep 2011 04:00:00 +0100

(New York University) An examination of a congestion-pricing pilot program in Portland, Ore., finds that congestion pricing strategies benefit from land-use planning that provides households with alternative ways to travel. (Source: EurekAlert! - Social and Behavioral Science)

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“Correcting” ulcers?

Surgical Endoscopy — Thu, 22 Sep 2011 05:51:10 +0100

Content Type Journal ArticleCategory Letter To The EditorPages 1-1DOI 10.1007/s00464-011-1915-7Authors David Cha, Department of Surgery, State University of New York, Stony Brook, NY, USAJoshua R. Karas, Department of Surgery, State University of New York, Stony Brook, NY, USARoberto Bergamaschi, Department of Surgery, State University of New York, Stony Brook, NY, USA Journal Surgical EndoscopyOnline ISSN 1432-2218Print ISSN 0930-2794 (Source: Surgical Endoscopy)

Does adding a lesser-curvature gastrogastric plication suture reduce the need for revision after laparoscopic adjustable gastric band placement?

Surgical Endoscopy — Thu, 22 Sep 2011 05:47:53 +0100

Conclusion Adding gastrogastric plication sutures offers no benefit of reducing the rate of revision after LAGB surgery. Content Type Journal ArticlePages 1-4DOI 10.1007/s00464-011-1910-zAuthors Jonathan Zagzag, New York University Langone Medical Center, 530 First Avenue, Suite 10-S, New York, NY 10016, USABradley F. Schwack, New York University Langone Medical Center, 530 First Avenue, Suite 10-S, New York, NY 10016, USAHeekoung Youn, New York University Langone Medical Center, 530 First Avenue, Suite 10-S, New York, NY 10016, USAChristine Ren Fielding, New York University Langone Medical Center, 530 First Avenue, Suite 10-S, New York, NY 10016, USAGeorge A. Fielding, New York University Langone Medical Center, 530 First Avenue, Suite 10-S, New York, NY 10016, USAMari...

Risks Seen for Children Of Illegal Immigrants

NYT Health — Wed, 21 Sep 2011 03:30:43 +0100

Children whose parents are illegal immigrants or who lack legal status themselves face “uniformly negative” effects on their social development throughout youth, a study says. (Source: NYT Health)

Illegal Immigrant Parents Pass a Burden, Study Says

NYT Health — Wed, 21 Sep 2011 00:22:58 +0100