MedWorm: Molluscum Contagiosum

Atypical cutaneous lesions of

Indian Journal of Dermatology, Venereology and Leprology — Tue, 09 Mar 2010 14:10:06 +0100

We report a case with verrucous lesions over nose and face due to Penicillium marneffei infection after HAART treatment. A 28-year-old man presented, after two weeks of HAART treatment, with multiple erythematous, scaly, papules and nodules with central necrosis predominantly in face and both extremities and scrotum. Microbiological investigations confirmed the diagnosis of Penicillium marneffei infection. This is perhaps the first case report with such manifestation due to Penicillium marneffei infection. (Source: Indian Journal of Dermatology, Venereology and Leprology)

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What Is Molluscum Contagiosum? What Causes Molluscum Contagiosum?

Dermatology News From Medical News Today — Thu, 18 Feb 2010 08:00:00 +0100

Molluscum contagiosum is a contagious skin infection caused by the molluscum contagiosum virus (MCV) that causes raised, pearl-like nodules or papules on the skin - these growths are called molluscum bodies, mollusca or condyloma subcutaneum. The virus belongs to the family called the Poxviridae. The molluscum contagiosum virus is also known as the molluscipoxvirus... (Source: Dermatology News From Medical News Today)

Molluscum contagiosum: Common skin infection spreads easily

MayoClinic.com Full Feed — Tue, 09 Feb 2010 06:00:00 +0100

Molluscum contagiosum — Comprehensive overview covers symptoms, causes, treatment of this common skin infection. (Source: MayoClinic.com Full Feed)

Vertically Transmitted Molluscum Contagiosum Infection

PEDIATRICS — Mon, 01 Feb 2010 16:03:21 +0100

We report a case of vertically transmitted molluscum contagiosum viral infection in which the maternal infection was clinically documented before vaginal delivery. The aim of this report is to make practitioners aware that molluscum infections in neonates are likely vertically transmitted. (Source: PEDIATRICS)

Neonatal Molluscum Infections Likely Vertically Transmitted

Modern Medicine — Tue, 12 Jan 2010 00:00:00 +0100

Neonatal molluscum contagiosum infections are probably transmitted vertically, based on the findings of a case study published online Jan. 11 in Pediatrics. (Source: Modern Medicine)

Atypical cutaneous lesions of Penicillium marneffei infection as a manifestation of the immune reconstitution inflammatory syndrome after highly active antiretroviral therapy

Indian Journal of Dermatology, Venereology and Leprology — Wed, 06 Jan 2010 14:01:46 +0100

We report a case with verrucous lesions over nose and face due to Penicillium marneffei infection after HAART treatment. A 28-year-old man presented, after two weeks of HAART treatment, with multiple erythematous, scaly, papules and nodules with central necrosis predominantly in face and both extremities and scrotum. Microbiological investigations confirmed the diagnosis of Penicillium marneffei infection. This is perhaps the first case report with such manifestation due to Penicillium�...

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[What's new in dermatological therapy?]

Annales de Dermatologie et de Cenereologie — Tue, 01 Dec 2009 00:00:00 +0100

Authors: Modiano P The medical literature was reviewed to identify new dermatological therapies that appeared between October 2008 and October 2009. Randomized studies, cohort studies, metaanalyses were given priority. However, nonrandomized studies as well as clinical case studies were retained if they presented original findings. Fifty-four articles were selected on the following diseases : psoriasis, pemphigoid, pemphigus, hidradenitis, lichen, progressive systematic sclerosis, lupus, atopic dermatitis, urticaria, sexually transmitted diseases, warts, molluscum contagiosum, actinic keratoses, acne. PMID: 20110060 [PubMed - as supplied by publisher] (Source: Annales de Dermatologie et de Cenereologie)

Molluscum contagiosum and dental caries: A pertinent combination

Journal of Indian Society of Pedodontics and Preventive Dentistry — Sat, 14 Nov 2009 13:59:42 +0100

Conclusion: The higher incidence of Molluscum contagiosum in children residing in orphanages as compared to the normal population of the same age group was reflected in the higher incidence of DMFT/deft in orphanages as compared to the normal population. (Source: Journal of Indian Society of Pedodontics and Preventive Dentistry)

Mucocutaneous manifestations in 150 HIV-infected Indian patients and their relationship with CD4 lymphocyte counts

International Journal of STD and AIDS — Fri, 30 Oct 2009 00:05:25 +0100

Mucocutaneous findings in 150 HIV+ve cases (F, 79; M, 71) were evaluated over a one-year period. Mucocutaneous manifestations were seen in 96% with 2.9 mean number of dermatoses and mean cluster of differentiation (CD4) count of 196.33 cells/mm3. The highest number of mean dermatoses, 3.29, was seen in individuals with severe immunosuppression. The most common mucocutaneous manifestation seen was candidiasis (35.33%), followed by seborrhoeic dermatitis (31.33%), oral pigmentation (29.33%), xerosis/ichthyosis (22.67%), pyodermas (22%), periodontitis (17.33%) and nail pigmentation (16.67%). Patient stratification according to the WHO immunological staging, according to CD4 counts, showed a statistically significant association (P < 0.05) for candidiasis, scabies, paronychia, oral pigmenta...

[Molluscum contagiosum: Descriptive study.]

Anales de Pediatria — Fri, 30 Oct 2009 00:00:00 +0100

CONCLUSIONS: Atopic dermatitis and swimming-pool attendance were associated in our study with a higher frequency and number of molluscum contagiosum. Although different therapeutic options must be evaluated depending on the patient and clinical skills, curettage is the most frequent treatment performed by dermatologists. PMID: 19880360 [PubMed - as supplied by publisher] (Source: Anales de Pediatria)

Immune reconstitution inflammatory syndrome involving the skin

Clinical And Experimental Dermatology — Thu, 22 Oct 2009 23:00:00 +0100

Conclusions. New skin lesions were very common in this cohort, with the majority being women and patients with very low baseline CD4 counts. (Source: Clinical And Experimental Dermatology)

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FLIP-mediated autophagy regulation in cell death control

Nature Cell Biology — Sun, 18 Oct 2009 00:00:00 +0100

Authors: Jong-Soo Lee, Qinglin Li, June-Yong Lee, Sun-Hwa Lee, Joseph H. Jeong, Hye-Ra Lee, Heesoon Chang, Fu-Chun Zhou, Shou-Jiang Gao, Chengyu Liang & Jae U. Jung Autophagy is an active homeostatic degradation process for the removal or turnover of cytoplasmic components wherein the LC3 ubiquitin-like protein undergoes an Atg7 E1-like enzyme/Atg3 E2-like enzyme-mediated conjugation process to induce autophagosome biogenesis. Besides its cytoprotecive role, autophagy acts on cell death when it is abnormally upregulated. Thus, the autophagy pathway requires tight regulation to ensure that this degradative process is well balanced. Two death effector domains (DED1/2) containing cellular FLICE-like inhibitor protein (cFLIP) and viral FLIP (vFLIP) of Kaposi's sarcoma-associated herpesviru...

Treatment for anogenital molluscum contagiosum.

American Family Physician — Wed, 14 Oct 2009 23:00:00 +0100

Authors: Brown M, Paulson C, Henry SL PMID: 19835348 [PubMed - in process] (Source: American Family Physician)

Adult self-healing papular mucinosis on genital skin

Clinical And Experimental Dermatology — Fri, 09 Oct 2009 23:00:00 +0100

We report a unique case of papular mucinosis on genital skin. The lesion was initially misdiagnosed and mistreated as molluscum contagiosum. The histological sections showed a large amount of mucin with sparse plump fibroblasts. The papules resolved in a few weeks, indicating a very rare form of the adult variant of self-healing papular mucinosis. Genital localization of this peculiar mucinosis, which we suspect may be more common than reported, is an important clinical simulator of sexually transmitted disease, and correct diagnosis is important for appropriate treatment. (Source: Clinical And Experimental Dermatology)

Factors and outcome in BK virus nephropathy in a Hispanic kidney transplant population

Transplant Infectious Disease — Sun, 04 Oct 2009 23:00:00 +0100

D. Pérez-Torres, J. Bertrán-Pasarell, E. Santiago-Delpín, M. González-Ramos, S. Medina-Mangual, L. Morales-Otero, Z. González-Caraballo. Factors and outcome in BK virus nephropathy in a Hispanic kidney transplant population.Transpl Infect Dis 2009. All rights reserved BK virus nephropathy (BKVN) is an increasingly recognized cause of kidney allograft loss and is thought to be related to the newer, more potent immunosuppressive agents. Conflicting information has been reported on risk factors for BK infection. To determine incidence, associated factors, and outcome of BKVN in our kidney transplant population in order to improve identification and management. Kidney transplants from January 2000 to December 2005 were retrospectively reviewed. Data were collected for patients with biopsy...

Comparative Study on the Efficacy, Safety, and Acceptability of Imiquimod 5% Cream versus Cryotherapy for Molluscum Contagiosum in Children

Pediatric Dermatology — Sat, 03 Oct 2009 23:00:00 +0100

Abstract: To compare the efficacy, safety and acceptability of imiquimod (IMQ) 5% cream with cryotherapy for the treatment of molluscum contagiosum (MC) in children. Prospective, randomized, comparative, observer blinded study. A total of 74 children, with MC were divided randomly to receive treatment with either IMQ 5% cream (group A) 5 days a week or cryotherapy (group B) once a week until clinical cure or up to a maximum of 16 weeks. All the patients were followed up weekly during active treatment. The patients were followed-up for 6 months after clinical cure to look for recurrence. In the IMQ group (group A), the overall complete cure rate was 91.8% (34 of 37), 22 of the 37 patients cleared by the end of 6 weeks and 12 more patients cleared by the end of 12 weeks, while the remaining ...

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Increased expression of human beta-defensin 3 in mollusca contagiosum

Clinical And Experimental Dermatology — Mon, 21 Sep 2009 23:00:00 +0100

We report a marked increase in hBD-3 immunoreactivity in MC lesions in contrast to hBD-2, which was only marginally increased. We suggest a role for the hBD-3 peptide in MC pathogenesis. (Source: Clinical And Experimental Dermatology)

Rashes and Fever in Children: Sorting Out the Potentially Dangerous, Part 3

Consultant Live — Fri, 28 Aug 2009 12:30:01 +0100

Children who present with rash and fever can be divided into 3 groups: those with features of serious illness who require immediate intervention, those with clearly recognizable viral syndromes, and those with early or undifferentiated rash. The morphology of lesions among children with symptoms of serious illness offers clues to the underlying cause. Fever accompanied by pharyngitis and a “sandpaper” rash that begins around the neck suggests scarlet fever. In most children with fever and rash who have clearly recognizable viral illnesses, such as measles or erythema infectiosum, diagnosis is clinical and therapy includes parental education and reassurance with appropriate follow-up. Viral illnesses characterized by the presence of umbilicated lesions include several relatively benign ...

Topical calcineurin inhibitors compromise stratum corneum integrity, epidermal permeability and antimicrobial barrier function

Experimental Dermatology — Sun, 23 Aug 2009 23:00:00 +0100

Conclusions: Our results demonstrate that TCIs induce negative effects on the skin barrier including permeability and antimicrobial functions, which are mediated by decreasing epidermal lipid synthesis, lamellar body secretion and antimicrobial peptides expression through suppression of cytokine such as IL-1[alpha], therefore co-treatment with PLM would be helpful to overcome these negative effects. (Source: Experimental Dermatology)

Standard guidelines for electrosurgery with radiofrequency current

Indian Journal of Dermatology, Venereology and Leprology — Wed, 12 Aug 2009 10:19:22 +0100

Mutalik SharadIndian Journal of Dermatology, Venereology, and Leprology 2009 75(8):83-89Definition: Radiofrequency (RF) induces thermal destruction of the targeted tissue by an electrical current at a frequency of 0.5 MHz (RF). As the electrode tip is not heated, there is minimal thermal damage to the surrounding tissues, producing good esthetic results. Therefore, RF ablation is also known as cold ablation or &quot;coblation.&quot; Modality: It has three modes of operation: (a) Cut, (b) cut and coagulate and (c) coagulate. Therefore, it can be used for various purposes like incision, ablation, fulguration, shave excision and coagulation. Because of the coagulation facility,...

Disfiguring molluscum contagiosum in a HIV-positive patient responding to antiretroviral therapy

Indian Journal of Dermatology — Thu, 30 Jul 2009 10:54:28 +0100

We present a case of agminate MC occurring in a patient with acquired immunodeficiency disease responding to highly active antiretroviral therapy. (Source: Indian Journal of Dermatology)

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Necrotizing fasciitis caused by Cryptococcus neoformans in a patient with pemphigus vegetans

Clinical And Experimental Dermatology — Tue, 28 Jul 2009 23:00:00 +0100

We present the case of a 55-year-old woman with pemphigus vegetans, who developed cryptococcal NF in the legs. She had been treated with immunosuppressants including plasmapheresis and pulse therapy with steroid and cyclophosphamide. Cryptococcal NF localized to the legs is very rare. Because diagnosis and treatment of cryptococcal infection is often delayed, clinicians should be aware of the possibility of cryptococcal infection when antibacterial therapy is not effective in an immunocompromised patient. (Source: Clinical And Experimental Dermatology)

Original papers Usefulness of dermoscopy for diagnosing pearly penile papules

Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house — Wed, 22 Jul 2009 10:29:33 +0100

Conclusions: Finding the above-mentioned dermatoscopic features of pearly penile papules allows one to establish the diagnosis and to restrict the use of therapy. Also, differentiation of pearly penile papules and genital warts in patients with both diseases coexisting allows one to restrict the area of treatment. (Source: Articles of Advances in Dermatology and Allergology - TERMEDIA publishing house)

Immunosuppressants/rituximab/thalidomide: Ecthyma gangrenosum, molluscum contagiosum and fatal cerebral toxoplasmosis: case report

Reactions — Mon, 13 Jul 2009 10:50:06 +0100

(Source: Reactions)

Confluent molluscum contagiosum covering the eyelids of an HIV-positive child

Clinical and Experimental Ophthalmology — Sat, 11 Jul 2009 23:00:00 +0100

(Source: Clinical and Experimental Ophthalmology)

Immunosuppressants/rituximab/thalidomide: Ecthyma gangrenosum, molluscum contagiosum and fatal cerebral toxoplasmosis: case report.

Reactions Weekly — Sat, 11 Jul 2009 10:50:03 +0100

Page: 19 (Source: Reactions Weekly)

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Molluscum contagiosum involving an epidermoid cyst with xanthogranuloma-like reaction in an HIV-infected patient

Journal of Cutaneous Pathology — Mon, 06 Jul 2009 23:00:00 +0100

Conclusion: MC infections are common, however MC associated with epidermoid cysts is infrequent. A few cases of MC occurring in epidermoid cysts have previously been reported. We are presenting a case of MC involving an epidermoid cyst in an AIDS patient, with a unique xanthogranuloma-like reaction. Xanthogranulomatous (XG) reactions have been infrequently reported in association with other viral infections, however, poxvirus-associated XG reaction has only been observed in animals. This is the first reported case of MC-associated XG reaction in humans. Aldabagh B, Ly MN, Hessel AB, Usmani AS. Molluscum contagiosum involving an epidermoid cyst with xanthogranuloma-like reaction in an HIV-infected patient. (Source: Journal of Cutaneous Pathology)

Disfiguring molluscum contagiosum in a HIV-positive patient responding to antiretroviral therapy

Indian Journal of Dermatology — Sun, 05 Jul 2009 10:51:15 +0100

We present a case of agminate MC occurring in a patient with acquired immunodeficiency disease responding to highly active antiretroviral therapy. (Source: Indian Journal of Dermatology)

Phenotype of atopic dermatitis subjects with a history of eczema herpeticum

Journal of Allergy and Clinical Immunology — Sun, 21 Jun 2009 23:00:00 +0100

Conclusion: Subjects with AD in whom eczema herpeticum develops have more severe TH2-polarized disease with greater allergen sensitization and more commonly have a history of food allergy, asthma, or both. They are also much more likely to experience cutaneous infections with S aureus or molluscum contagiosum. (Source: Journal of Allergy and Clinical Immunology)

Pimecrolimus: Molluscum contagiosum in a child: case report

Reactions — Tue, 09 Jun 2009 16:41:07 +0100

(Source: Reactions)

Pimecrolimus: Molluscum contagiosum in a child: case report.

Reactions Weekly — Sun, 07 Jun 2009 18:23:59 +0100

Page: 27 (Source: Reactions Weekly)

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Molluscum contagiosum after eyebrow shaping: a beauty salon hazard

Clinical And Experimental Dermatology — Sun, 17 May 2009 23:00:00 +0100

(Source: Clinical And Experimental Dermatology)

Detection of molluscum contagiosum virus gene transcripts by in situ hybridization

Journal of Dermatological Science — Thu, 07 May 2009 13:48:03 +0100

Molluscum contagiosum virus (MCV) and human papillomavirus (HPV) are double-stranded DNA viruses that cause various mucocutaneous infections and are tumorigenic. Compared to MCV, complete genome expression and regulation of HPV in the stratified epithelium have been extensively studied and well characterized using in situ hybridization (ISH) and immunohistochemistry . The HPV genome encodes only 8–9 proteins, which are classified into two groups, the early (E) and late (L) regions. Early gene transcription initiates before the onset of vegetative DNA replication, increases with progressive keratinocyte differentiation, and reaches a maximum in the upper spinous layer, just before the granular layer. The L region messages appear concomitant with or after the onset of vegetative viral DNA ...

Molluscum contagiosum infestation in an epidermal cyst: still infectious?

Journal of the European Academy of Dermatology and Venereology — Wed, 29 Apr 2009 04:00:00 +0100

(Source: Journal of the European Academy of Dermatology and Venereology)

Detection of viral DNA in nonlesional skin of patients with molluscum contagiosum and on environmental fomites

British Journal of Dermatology — Thu, 16 Apr 2009 04:00:00 +0100

(Source: British Journal of Dermatology)

Multiple Epidermolytic Acanthomas Must Not be Confused with Genital Human Papillomavirus Infection.

Acta Derm Venereol A... — Tue, 07 Apr 2009 13:28:56 +0100

We describe two patients with multiple epidermolytic acanthomas on the scrotum initially referred to our clinic as genital warts. Both patients presented with multiple tan-colored warty papules scattered on the scrotal skin. Biopsy revealed hyperkeratosis, hypergranulosis, and clear cell changes consistent with epidermolytic acan thoma. Human papillomavirus was not detected and the lesions cleared rapidly with a liquid nitrogen cryoprobe. Despite only a few reports of multiple epidermolytic acan thomas of the scrotum, it may not be as rare as previously thought. In addition, genital localization of the wart-like lesions may lead to confusion with other conditions such as condylomata acuminata, molluscum contagiosum, or bowenoid papulosis. PMID: 19326003 [PubMed - in process] (Source: A...

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Disseminated cryptococcosis in an HIV-negative patient.

Tropical Doctor — Tue, 24 Mar 2009 02:10:03 +0100

Authors: Rajpal S, Dwivedi S, Chaudhary S A young, unmarried, immunocompetent female presented with complaints of fever and altered sensorium, along with lesions over the face and trunk. A provisional diagnosis of disseminated herpes simplex with giant molluscum contagiosum was made. However, cutaneous biopsy of the lesions showed numerous cryptococcal organisms which stained positive to periodic acid-Schiff. This case is reported to sensitise physicians to keep cryptococcosis as a differential diagnosis in such types of skin lesions, as the lesions resemble that of molluscum contagiosum very closely. PMID: 19299302 [PubMed - in process] (Source: Tropical Doctor)

Cantharidin Use Among Pediatric Dermatologists in the Treatment of Molluscum Contagiosum

Pediatric Dermatology — Wed, 18 Mar 2009 04:00:00 +0100

Abstract: Cantharidin is cited often in the dermatology and pediatric literature as a valuable treatment option for molluscum contagiosum (MC). However, there have been no prospective, randomized, vehicle-controlled trials that have been able to quantify cantharidin's efficacy in MC. The purpose of this study was to determine the breadth of usage of cantharidin, most frequently used protocols, and common side effects seen with use of cantharidin. An eighteen question survey was administered to the Society of Pediatric Dermatology. The survey sought to evaluate treatments used in MC and experiences with cantharidin including: protocol, side effects, specific products used, and satisfaction with cantharidin. A total of 300 surveys were distributed via email, 101 surveys were initiated, and 9...

Molluscum contagiosum: immunomorphological aspects of keratinocytes markers of differentiation and adhesion

Journal of Cutaneous Pathology — Tue, 17 Mar 2009 00:00:00 +0100

Conclusion: Infection by Molluscipox virus alters keratinocyte differentiation status. The presence of K14 and p63 in spinous layer, as well as early expression of involucrin and filaggrin, associated to a hyperproliferative state disclosed by K16 expression, may be a result of disruption in keratinocytes maturation process. The changes observed at ANAE may represent early events in keratinization disturbance. Callegaro CF, Sotto MN. Molluscum contagiosum: immunomorphological aspects of keratinocytes markers of differentiation and adhesion. (Source: Journal of Cutaneous Pathology)

Molluscum contagiosum arising in melanocytic nevus and in superficial spreading melanoma.

Journal of Cutaneous Pathology — Sun, 15 Mar 2009 11:31:31 +0100

We present the case of MC in common melanocytic nevus and the first case of MC in superficial spreading malignant melanoma. Complete destruction of melanocytes and melanoma cells occurred on the site of MC infection. MC virus might be considered as a future candidate for viral oncolysis in cutaneous melanoma patients with advanced disease. PMID: 19278433 [PubMed - in process] (Source: Journal of Cutaneous Pathology)

Intraoral molluscum contagiosum imitating a squamous-cell carcinoma in an immunocompetent person – case report and review of the literature

International Journal of Oral and Maxillofacial Surgery — Thu, 12 Mar 2009 00:00:00 +0100

Abstract: A case of intraoral molluscum contagiosum involving the right distal alveolar bridge of an immunocompetent person is reported. A review of the literature, with only five previously published cases, revealed that involvement of the oral soft tissues is rare. (Source: International Journal of Oral and Maxillofacial Surgery)

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Intraoral molluscum contagiosum imitating a squamous-cell carcinoma in an immunocompetent person - case report and review of the literature.

International Journal of Oral and Maxillofacial Surgery — Tue, 10 Mar 2009 04:00:00 +0100

Authors: Scherer P, Fries J, Mischkowski RA, Neugebauer J, Scheer M, Zöller JE A case of intraoral molluscum contagiosum involving the right distal alveolar bridge of an immunocompetent person is reported. A review of the literature, with only five previously published cases, revealed that involvement of the oral soft tissues is rare. PMID: 19282150 [PubMed - as supplied by publisher] (Source: International Journal of Oral and Maxillofacial Surgery)

Parental Satisfaction, Efficacy, and Adverse Events in 54 Patients Treated With Cantharidin for Molluscum Contagiosum Infection

Clinical Pediatrics — Mon, 09 Mar 2009 04:00:00 +0100

Conclusions The results contribute to the data supporting cantharidin as a safe and effective treatment of molluscum contagiosum. Compared with other treatments, it appears to be equally effective and well-tolerated and should be considered a potential front-line treatment. (Source: Clinical Pediatrics)

Molluscum Contagiosum

MedicineNet Hepatitis C General — Fri, 06 Mar 2009 07:00:00 +0100

Title: Molluscum ContagiosumCategory: Diseases and ConditionsCreated: 3/6/2009Last Editorial Review: 3/6/2009 (Source: MedicineNet Hepatitis C General)

An open, nonrandomized, comparative study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum

Indian Journal of Dermatology, Venereology and Leprology — Fri, 16 Jan 2009 04:12:33 +0100

Conclusions: The results of this study suggest that both 5% imiquimod cream and 10% KOH solution are equally effective in molluscum contagiosum though KOH has a faster onset of action. However, KOH solution is associated with a higher incidence of side effects. (Source: Indian Journal of Dermatology, Venereology and Leprology)

Giant cutaneous horn

Indian Journal of Dermatology — Sat, 03 Jan 2009 11:18:20 +0100

We report a patient with giant cutaneous horn on the leg successfully treated by excision and wound closure. (Source: Indian Journal of Dermatology)

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Sebaceous gland hyperplasia of the foreskin.

Clinical And Experimental Dermatology — Tue, 09 Dec 2008 05:00:00 +0100

Authors: Ena P, Origa D, Massarelli G Summary Two men, aged in their 20s, presented with multiple, soft, rounded papules on the prepuce. The lesions were centrally umbilicated, resembling molluscum contagiosum, but clearly distinct from Tyson's glands. Surface microscopy showed well-defined, milky-white, bag-shaped structures, which under histological examination were found to be sebaceous glands with various features of hyperplasia. A lymphocytic T-cell infiltrate, closely associated with progressive degeneration and destruction of the sebocytes, was visible around the glands. In the differential diagnosis of penile papular lesions, this unusual clinical presentation supported by dermatoscopy is consistent with preputial sebaceous gland hyperplasia. As both patients had a prominent T-...

Congenital Molluscum Contagiosum: Report of Four Cases and Review of the Literature

Pediatric Dermatology — Thu, 02 Oct 2008 04:00:00 +0100

We report on four more infants with congenital molluscum, two children with congenital lesions, and two children with onset of lesions at 6 weeks of age. Two children had single cutaneous lesions on the extremities and two had lesions of the scalp consistent with the site of cervical pressure. Congenital molluscum appears to be a more common entity than previously reported. Vertical transmission of molluscum should be considered for all infantile cases of molluscum. (Source: Pediatric Dermatology)

Co-infection of molluscum contagiosum virus and cryptococcosis in the same skin lesion in a HIV-infected patient.

Journal of Cutaneous Pathology — Wed, 01 Oct 2008 04:00:00 +0100

Authors: Annam V, Inamadar AC, Palit A, Yelikar BR A young human immunodeficiency virus-infected man was admitted in unconsciousness state. Few papular skin lesions resembling molluscum contagiosum (MC) were present on the face. He was found to have cryptococcal meningitis using India ink preparation of cerebrospinal fluid. Histopathological examination of skin lesion revealed the presence of capsulated yeast forms of Cryptococcus within the lesion of MC. The co-existence of MC and cryptococcosis in the same cutaneous lesion is rare, and it could be because of immunosuppression (low CD4 count). PMID: 18544053 [PubMed - in process] (Source: Journal of Cutaneous Pathology)

Curettage treatment for molluscum contagiosum: a follow-up survey study

British Journal of Dermatology — Mon, 15 Sep 2008 04:00:00 +0100

Conclusions The main risk factor for treatment failure is lesion number, underlining the importance of the early detection of the lesions or, alternatively, emphasizing the need for therapeutic options other than curettage in patients with numerous lesions. (Source: British Journal of Dermatology)

Curettage treatment for molluscum contagiosum: a follow-up survey study.

The British Journal of Dermatology — Mon, 15 Sep 2008 04:00:00 +0100

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Efalizumab: First report of molluscum contagiosum: case report

Reactions — Tue, 12 Aug 2008 08:12:18 +0100

(Source: Reactions)

Efalizumab: First report of molluscum contagiosum: case report.

Reactions Weekly — Sat, 09 Aug 2008 09:25:03 +0100

Page: 15 (Source: Reactions Weekly)

Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome

Indian Journal of Ophthalmology — Sat, 09 Aug 2008 06:54:41 +0100

This article is a comprehensive update of the important anterior segment and adnexal manifestations in HIV-positive patients with special reference to their prevalence in the Indian population. (Source: Indian Journal of Ophthalmology)

The epidemiology of Molluscum contagiosum in HIV-seropositive patients: a unique entity or insignificant finding?

International Journal of STD and AIDS — Mon, 28 Jul 2008 04:00:00 +0100

This study evaluates the current literature concerning the clinical features of MC in this population, the utility of MC as a predictor of immunocompromised state and the natural history of MC and HIV in patients with these co-morbidities. PubMed database search for English-written original studies found 10 of them, all enrolled for HIV patients. There was no unique feature of MC in adult HIV patients; nevertheless, the appearance of MC lesions in adult men should require evaluation for immunocompromised state. In HIV-positive patients, MC tends to occur during the advanced phase of the disease. MC in children is rarely associated with immunodeficiency and usually no further evaluation is needed. In patients with known HIV infection, the presence of MC may signify advancing immunosuppressi...

Disseminated Giant Molluscum Contagiosum in a Patient with Idiopathic CD4+ Lymphocytopenia

Dermatology — Thu, 26 Jun 2008 15:17:46 +0100

Dermatology 2008;217:196-198 (DOI:10.1159/000141649) (Source: Dermatology)

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Resolution of giant Molluscum contagiosum with antiretroviral therapy

Indian Journal of Dermatology, Venereology and Leprology — Sat, 21 Jun 2008 20:11:14 +0100

Sen Sumit, Bhaumik ParnaIndian Journal of Dermatology, Venereology and Leprology 2008 74(3):267-268 (Source: Indian Journal of Dermatology, Venereology and Leprology)

Resolution of giant Molluscum contagiosum with antiretroviral therapy

Indian Journal of Dermatology, Venereology and Leprology — Tue, 17 Jun 2008 22:18:14 +0100

Sen Sumit, Bhaumik ParnaIndian Journal of Dermatology, Venereology and Leprology 2008 74(3):269-270 (Source: Indian Journal of Dermatology, Venereology and Leprology)

Co-infection of molluscum contagiosum virus and cryptococcosis in the same skin lesion in a HIV-infected patient

Journal of Cutaneous Pathology — Tue, 10 Jun 2008 03:54:38 +0100

Journal of Cutaneous Pathology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. A young human immunodeficiency virus-infected man was admitted in unconsciousness state. Few papular skin lesions resembling molluscum contagiosum (MC) were present on the face. He was found to have cryptococcal meningitis using India ink preparation of ... (Source: Journal of Cutaneous Pathology)

An overview of molluscum contagiosum: a viral skin condition.

Nursing Standard — Sun, 01 Jun 2008 04:00:00 +0100

Authors: Gould D Molluscum contagiosum is a virus that causes characteristic pearly lesions on the surface of the skin. Small clusters of mollusca are a nuisance rather than a serious health problem. However, the mollusca can be more widespread and disfiguring in people with impaired cell-mediated immunity. Molluscum contagiosum virus is common in children. In adults it can also be contracted during sexual activity and might indicate a need for diagnostic testing for other, more serious sexually transmitted infections in young, sexually active adults. PMID: 18616033 [PubMed - in process] (Source: Nursing Standard)

Methotrexate: Molluscum contagiosum in an elderly patient: case report

Reactions — Mon, 26 May 2008 14:39:50 +0100

(Source: Reactions)

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Methotrexate: Molluscum contagiosum in an elderly patient: case report.

Reactions Weekly — Sat, 24 May 2008 14:40:59 +0100

Page: 29 (Source: Reactions Weekly)

Molluscum contagiosum in human immunodeficiency virus infected patients

Table of Contents : Indian Journal of Dental Research : 2006 - 17(3) — Tue, 29 Apr 2008 18:52:49 +0100

Chaudhary Mayur, Kulkarni MeenaIndian Journal of Dental Research 2008 19(2):155-159 (Source: Table of Contents : Indian Journal of Dental Research : 2006 - 17(3))

Prominent eosinophilic intranuclear inclusions in melanocytes of a melanocytic nevus: the aftermath of an infection with molluscum contagiosum? A case report

Journal of Cutaneous Pathology — Tue, 22 Apr 2008 18:14:50 +0100

Journal of Cutaneous Pathology, Volume 0, Issue 0, Page ???, OnlineEarly Articles. A 65-year-old Latino man presented to his dermatologist for the removal of two melanocytic nevi from the back. The first nevus was removed from the right scapula and contained melanocytes with prominent eosinophilic nuclear inclusion bodies. The second ... (Source: Journal of Cutaneous Pathology)

One-Year Experience with Candida Antigen Immunotherapy for Warts and Molluscum

Pediatric Dermatology — Tue, 22 Apr 2008 04:03:23 +0100

We report our 1-year experience with intralesional candida antigen therapy for both warts and molluscum contagiosum. A retrospective chart review was ... (Source: Pediatric Dermatology)

Etanercept/infliximab: Human papillomavirus infection (first report with etanercept) and molluscum contagiosum: 2 case reports

Reactions — Mon, 21 Apr 2008 07:38:40 +0100

(Source: Reactions)

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Etanercept/infliximab: Human papillomavirus infection (first report with etanercept) and molluscum contagiosum: 2 case reports.

Reactions Weekly — Sat, 19 Apr 2008 07:37:25 +0100

Page: 19 (Source: Reactions Weekly)

Cutaneous pseudolymphoma associated with molluscum contagiosum: a case report

International Journal of Dermatology — Mon, 14 Apr 2008 22:59:23 +0100

We report an unusual case of molluscum contagiosum associated with pseudolymphoma in an otherwise healthy young woman. She presented with a 2-week history of a rapidly enlarging painful umbilicated nodule behind her right ear. With the clinical ... (Source: International Journal of Dermatology)

Expression of toll-like receptors in verruca and molluscum contagiosum.

J Korean Med Sci — Tue, 01 Apr 2008 04:00:00 +0100

Authors: Ku JK, Kwon HJ, Kim MY, Kang H, Song PI, Armstrong CA, Ansel JC, Kim HO, Park YM Recent studies indicate that several Toll-like receptors (TLRs) are implicated in recognizing viral structures and instigating immune responses against viral infections. The aim of this study is to examine the expression of TLRs and proinflammatory cytokines in viral skin diseases such as verruca vulgaris (VV) and molluscum contagiosum (MC). Reverse transcription-polymerase chain reaction and immunostaining of skin samples were performed to determine the expression of specific antiviral and proinflammatory cytokines as well as 5 TLRs (TLR2, 3, 4, 7, and 9). In normal human skin, TLR2, 4, and 7 mRNA was constitutively expressed, whereas little TLR3 and 9 mRNA was detected. Compared to normal skin (...

[Epidemiology, clinical picture and treatment of molluscum contagiosum: literature review]

Annales de Dermatologie et de Cenereologie — Tue, 01 Apr 2008 04:00:00 +0100

Authors: Vanhooteghem O, Henrijean A, de la Brassinne M PMID: 18420087 [PubMed - in process] (Source: Annales de Dermatologie et de Cenereologie)

Pattern of non-venereal dermatoses of female external genitalia in South India.

Dermatol Online J — Thu, 06 Mar 2008 20:16:22 +0100

This study highlights the importance of diagnosing non-venereal dermatoses and refutes the general misconception that all vulval itching is the result of fungal infection. The two most common causes of vulval itching observed in the study were lichen sclerosus and lichen simplex chronicus. PMID: 18319018 [PubMed - in process] (Source: Dermatol Online J)

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[Childhood dermatosis in a dermatology clinic of a general university hospital in Spain.]

Actas Dermo-Sifiliograficas — Sat, 01 Mar 2008 05:00:00 +0100

CONCLUSIONS: In most developed countries, atopic dermatitis is the most common dermatologic disease in children. In our study, however, melanocytic nevus was the most common presenting complaint, reflecting perhaps that there are more children in Spain with multiple nevi due to overexposure to sunlight or because of concern about melanoma among the population. Another possibility is that Spain has fewer cases of atopic dermatitis than more industrialized countries in northern Europe. Measures to avoid exposure to sunlight and use of sunscreen should be promoted during infancy. This could help slow the increase of melanoma in the adult population. PMID: 18346432 [PubMed - in process] (Source: Actas Dermo-Sifiliograficas)

Molluscum contagiosum.

Skinmed — Sat, 01 Mar 2008 05:00:00 +0100

Authors: Scheinfeld NS PMID: 18327001 [PubMed - indexed for MEDLINE] (Source: Skinmed)

Pharmacokinetics and Safety of Imiquimod 5% Cream in the Treatment of Molluscum Contagiosum in Children

Pediatric Dermatology — Mon, 25 Feb 2008 04:35:33 +0100

Pediatric Dermatology, Volume 25, Issue 1, Page 88-95, January/February 2008. Abstract: Imiquimod cream 5%, a toll-like receptor 7 agonist, induces α-interferon upon topical application, prompting off-label usage to treat children with molluscum contagiosum. We conducted an open-label study to measure serum drug concentration in ... (Source: Pediatric Dermatology)

Genital HPV Lesions and Molluscum Contagiosum Occurring in Patients Receiving Anti-TNF-a Therapy

Dermatology — Wed, 20 Feb 2008 14:45:51 +0100

Dermatology 2008;216:364-365 (DOI:10.1159/000117709) (Source: Dermatology)

Developer of Novel Treatment for Molluscum Announces Naturopathix, Inc. Commercial Spin Off

PRWeb: Medical Pharmaceuticals — Fri, 15 Feb 2008 08:12:36 +0100

Dr. Briant Burke, MD, developer of the patented, over-the-counter topical treatment for molluscum contagiosum called ZymaDerm, announced today that the Center for Biomedical Research, Inc. has launched a commercial spin off for e-commerce named Naturopathix, Inc. (PRWeb Feb 15, 2008) Read the full story at http://ww1.prweb.com/releases/2008/02/prweb693733.htm (Source: PRWeb: Medical Pharmaceuticals)

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Molluscum contagiosum

MayoClinic.com Full Feed — Sat, 09 Feb 2008 06:00:00 +0100

— Comprehensive overview covers symptoms, causes, treatment of this common skin infection.Sponsored by:Chemotherapy.com - http://www.chemotherapy.com (Source: MayoClinic.com Full Feed)

SKINSIGHT: Reflectance Confocal Microscopy of Molluscum Contagiosum

Archives of Dermatology — Mon, 21 Jan 2008 05:00:00 +0100

(Source: Archives of Dermatology)

A-Z Molluscum Contagiosum

HealthcareRepublic Clinical Articles — Mon, 10 Dec 2007 00:00:00 +0100

This common viral infection occasionally requires referral but can often be left untreated, writes Debra Sprague. (Source: HealthcareRepublic Clinical Articles)

Spreading bumps: molluscum contagiosum in the pediatric population.

Pediatric Annals — Sat, 01 Dec 2007 05:00:00 +0100

Authors: Nelson KC, Morrell DS PMID: 18229524 [PubMed - in process] (Source: Pediatric Annals)

Methotrexate: Molluscum contagiosum in an elderly patient: case report.

Reactions Weekly — Wed, 28 Nov 2007 01:33:45 +0100

Page: 23 (Source: Reactions Weekly)

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Methotrexate: Molluscum contagiosum in an elderly patient: case report

Reactions — Mon, 26 Nov 2007 13:48:40 +0100

(Source: Reactions)

Treatment of molluscum contagiosum with a pulsed dye laser: Pilot study with 19 children

JDDG — Fri, 09 Nov 2007 08:37:24 +0100

JDDG, Volume 0, Issue 0, Page ???, -Not available-. Summary Background: Molluscum contagiosum is a common, self-limiting viral disease of childhood caused by a poxvirus. Often the children themselves and their parents desire treatment for cosmetic reasons or because of pruritus. Laser therapy offers ... (Source: JDDG)

Identification and genotyping of molluscum contagiosum virus from genital swab samples by real-time PCR and Pyrosequencing.

Journal of Clinical Virology — Thu, 08 Nov 2007 05:00:00 +0100

CONCLUSIONS: These real-time PCR assays can be used for the rapid, sensitive, and specific detection of MCV and, when combined with Pyrosequencing, can further discriminate between MCV1 and MCV2. PMID: 17997134 [PubMed - as supplied by publisher] (Source: Journal of Clinical Virology)

ReBuilder Medical Technologies secures license to manufacture electronic molluscum contagiosum treatment system

News-Medical News Feed — Tue, 28 Aug 2007 12:46:00 +0100

ReBuilder Medical Technologies, Inc. has announced that it has negotiated an exclusive license from White Hall, Inc. for the micronized, amorphous silver ion technology to treat the highly contagious skin disease, Molluscum Contagiosum. (Source: News-Medical News Feed)

Case of AIDS disclosed by refractory pruritic xerosis and molluscum contagiosum

The Journal of Dermatology — Thu, 23 Aug 2007 09:33:59 +0100

The Journal of Dermatology Volume 34, Issue 9, Page 668-670, Sep 2007. (Source: The Journal of Dermatology)

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Molluscum Contagiosum Infection Associated with Pimecrolimus Use in Pityriasis Alba

Pediatric Dermatology — Mon, 06 Aug 2007 21:41:58 +0100

Pediatric Dermatology Volume 0, Issue 0, Page ???-???. Abstract: Atopic dermatitis is an inflammatory, chronically relapsing, highly pruritic skin disorder that has considerable impact on the quality of life. As corticosteroids are not ideal for long-term control of the disease because of their potential side ... (Source: Pediatric Dermatology)

Tacrolimus: Molluscum contagiosum: case report

Reactions — Sun, 05 Aug 2007 12:34:07 +0100

(Source: Reactions)

Tacrolimus: Molluscum contagiosum: case report.

Reactions Weekly — Sat, 04 Aug 2007 00:44:59 +0100

Page: 24 (Source: Reactions Weekly)

Molecular biology of cantharidin in cancer cells

Chinese Medicine — Wed, 04 Jul 2007 04:00:00 +0100

Herbal medicine is one of the forms of traditional medical practice. Traditional Chinese medicine (TCM) and traditional Vietnamese medicine (TVM) are well-known for their long-standing tradition of herbal medicine. Secreted by many species of blister beetle, most notably by the 'Spanish fly' (L. vesicatoria), cantharidin inhibits protein phosphatases 1 and 2A (PP1, PP2A). Blister beetle has been used in Asian traditional medicine to treat Molluscum contagiosum virus (MCV) infections and associated warts, and is now also used for cancer treatment. A combination of both genomic and postgenomic techniques was used in our studies to identify candidate genes affecting sensitivity or resistance to cantharidin. Cantharidin was not found to be related to multidrug resistance phenotype, suggesting ...

Cutaneous fungal and viral infections in athletes.

Clinics in Sports Medicine — Sun, 01 Jul 2007 04:00:00 +0100

Authors: Pleacher MD, Dexter WW Fungal and viral cutaneous infections are common among athletes and can develop quickly into widespread outbreaks. To prevent such outbreaks, the team physician must be familiar with common cutaneous infections including tinea corporis, tinea capitis, tinea pedis, herpes simplex, molluscum contagiosum, and human papillomaviruses. Appropriate treatment and management of these infections allows the athlete to safely return to play and safeguards teammates and opponents against the spread of these diseases. PMID: 17826191 [PubMed - in process] (Source: Clinics in Sports Medicine)

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Lymphangioma circumscriptum of the penis: a case report.

Acta Dermatovenerologica Alpina, Panonica, et Adriatica — Fri, 01 Jun 2007 04:00:00 +0100

We report a case of lymphangioma circumscriptum of the penis in a 19-year-old male. The lesions developed during puberty and resembled molluscum contagiosum and genital herpes. The case is presented because of its rarity and to increase diagnostic awareness and treatment with non-surgical intervention. PMID: 17992464 [PubMed - in process] (Source: Acta Dermatovenerologica Alpina, Panonica, et Adriatica)

Molluscum Contagiosum

Pediatric Dermatology — Wed, 30 May 2007 22:20:31 +0100

Pediatric Dermatology Volume 24, Issue 3, Page 334-335, May 2007. (Source: Pediatric Dermatology)

Exuberant molluscum contagiosum as a manifestation of the immune reconstitution inflammatory syndrome.

Dermatol Online J — Thu, 17 May 2007 22:59:50 +0100

We present a patient who developed extensive Molluscum Contagiosum (MC) lesions shortly after being started on HAART. With the progression of immunoreconstitution, the lesions healed spontaneously. Molluscum contagiosum lesions are presumably common in IRIS but underreported. We point out this case for its striking clinical picture and well-documented relation to immunoreconstitution to draw attention to this IRIS manifestation. PMID: 17498425 [PubMed - in process] (Source: Dermatol Online J)

What is the Best Treatment for Molluscum Contagiosum?

PediatricEducation.org — Mon, 14 May 2007 07:00:00 +0100

Discussion Molluscum contagiosum is a common viral skin infection caused by a poxvirus. They are small flesh-color papular lesions with central umbilication where the virus resides. They are painless and generally are 1-10 mm in size. They can occur anywhere on the skin. They often spontaneous resolve in 6-9 months, but can also have widespread dissemination (especially in patients with underlying dermatological conditions), pruritus, secondary bacterial superinfection, acute and chronic inflammatory changes, and scar formation. They can also be transmitted to others. There have been many treatments advocated. One recent prospective randomized trial in 124 children ages 1-18 years found that curettage was the most effective treatment with the lowest side effects, but it needed adequate ...

Prospective study to assess general practitioners' dermatological diagnostic skills in a referral setting.

The Australasian Journal of Dermatology — Tue, 01 May 2007 04:00:00 +0100

Authors: Moreno G, Tran H, Chia AL, Lim A, Shumack S A prospective study was conducted to assess general practitioners' diagnostic skills in a referral setting. The primary objective was to identify general practitioners' strengths and weaknesses in diagnosing a broad spectrum of skin conditions. The diagnoses of 315 skin conditions made by 165 general practitioners were compared with a reference standard. The reference standard was made up of 73 histopathological diagnoses, 119 dermatologists' clinical diagnoses and 123 dermatologists' diagnoses plus follow up. The diagnoses assigned by referring general practitioners were consistent with dermatologists' clinical diagnoses and histology (where available) in 57% of cases. General practitioners made the correct diagnosis in 44% of cases...

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Modified Curettage Technique for Molluscum Contagiosum

Pediatric Dermatology — Wed, 25 Apr 2007 13:19:22 +0100

Pediatric Dermatology Volume 24, Issue 2, Page 192-194, Mar 2007. (Source: Pediatric Dermatology)

Case Detection Rates of Molluscum Contagiosum in Childhood

Pediatric Dermatology — Wed, 25 Apr 2007 13:18:31 +0100

Pediatric Dermatology Volume 24, Issue 2, Page 198-199, Mar 2007. (Source: Pediatric Dermatology)

Molluscum Symptoms And Transmission

Dermatology News From Medical News Today — Sun, 08 Apr 2007 10:00:00 +0100

The full name of this viral skin infection is molluscum contagiosum and it is very contagious. The disease is caused by a pox virus of the Molluscipox virus genus. It most often affects infants and young children under the age of ten years, but the infection can occur in any age group and it has become more common in adults in recent years. [click link for full article] (Source: Dermatology News From Medical News Today)

Molluscum Treatment And Help

Dermatology News From Medical News Today — Sun, 08 Apr 2007 10:00:00 +0100

After exposure to molluscum contagiosum the first symptoms usually appear 2 to 12 weeks later and each lesion can last 6 to 8 weeks. If the lesions are not treated, then continuous spreading can mean that the infection can last up to 8 months and in some cases, as long as 5 years. It is therefore important that new growths should be treated as soon as they become large enough to see. [click link for full article] (Source: Dermatology News From Medical News Today)

Molluscum Symptoms And Transmission

Health News from Medical News Today — Sun, 08 Apr 2007 10:00:00 +0100

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Molluscum Treatment And Help

Health News from Medical News Today — Sun, 08 Apr 2007 10:00:00 +0100

Virabiotics launched a topical antiviral therapy [MolluscuDerm] for the treatment of molluscum contagiosum

Inpharma — Thu, 15 Feb 2007 06:05:15 +0100

(Source: Inpharma)

Virabiotics launched a topical antiviral therapy [MolluscuDerm] for the treatment of molluscum contagiosum.

Inpharma Weekly — Sun, 11 Feb 2007 10:16:02 +0100

(Source: Inpharma Weekly)

Fas-associated death domain-containing protein-mediated antiviral innate immune signaling involves the regulation of irf7.

Journal of Immunology — Wed, 07 Feb 2007 05:05:02 +0100

Authors: Balachandran S, Venkataraman T, Fisher PB, Barber GN The induction of type I (alphabeta) IFN following virus infection is necessary for the stimulation of effective antiviral host defense. In fibroblasts, a subset of primary genes (including those encoding IFN-beta and IFN-alpha4) are induced directly by intracellular dsRNA generated by the virus during its replication. These primary type I IFNs induce expression of IFN regulatory factor (IRF)-7, required for production of a second cascade of IFN-alpha subtypes and the further establishment of a complete antiviral state. Previously, we had reported on a role for Fas-associated death domain-containing protein (FADD) in the control of TLR-independent innate immune responses to virus infection. Our data in this study demonstrate ...

New and updated PRODIGY guidance

NeLM Headline News — Tue, 06 Feb 2007 00:00:00 +0100

The following new and updated PRODIGY guidance have been issued and are available at www.cks.library.nhs.uk. • Amenorrhoea • Angina • Asthma • Atrial fibrillation • Balanitis • Candida – oral • Diabetes - glycaemic control • Gastroenteritis • Hypertension • Molluscum contagiosum • Nappy rash • Otitis media - acute • Parkinsons disease • Polycystic ovary syndrome - NEW • Schizophrenia • Warts (including verrucas) (Source: NeLM Headline News)

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Disseminated cutaneous cryptococcosis in a patient with AIDS.

Revista do Instituto de Medicina Tropical de Sao Paulo — Tue, 23 Jan 2007 11:40:03 +0100

Authors: Dinato SL, Dinato MM, Nakanishi CP, Almeida JR, Romiti N The authors study a patient carrying AIDS, with exuberant dermatological manifestations of cryptococcosis. They stress the therapeutic effectiveness of short-term amphotericin B. The authors reviewed cases of cutaneous infection with Cryptococcus reported in the national and international literature, verifying that the frequency has increased with the AIDS epidemic. Also, they discuss about the differential diagnosis with some cases of dermatosis, particularly with the disseminated giant molluscum contagiosum. In relation to the therapy, they affirm that the choice of drug depends on the organ involved, as well as the immune state of the patient. PMID: 17221135 [PubMed - in process] (Source: Revista do Instituto de M...

A Prospective Randomized Trial Comparing the Efficacy and Adverse Effects of Four Recognized Treatments of Molluscum Contagiosum in Children

Pediatric Dermatology — Mon, 04 Dec 2006 10:40:33 +0100

Volume 23, Issue 6, Page 574-579, Nov 2006. (Source: Pediatric Dermatology)

Methemoglobinemia and CNS Toxicity after Topical Application of EMLA to a 4-Year-Old Girl with Molluscum Contagiosum

Pediatric Dermatology — Mon, 04 Dec 2006 10:33:47 +0100

Volume 23, Issue 6, Page 592-593, Nov 2006. (Source: Pediatric Dermatology)

Treatment of verrucae vulgaris and molluscum contagiosum with photodynamic therapy.

Dermatologic Clinics — Thu, 30 Nov 2006 01:21:02 +0100

Authors: Gold MH, Moiin A PMID: 17126744 [PubMed - in process] (Source: Dermatologic Clinics)

Interventions for molluscum contagiosum.

American Family Physician — Fri, 24 Nov 2006 02:04:02 +0100

Authors: Guirguis-Blake J PMID: 17111888 [PubMed - in process] (Source: American Family Physician)

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AIDS defining disease: Disseminated cryptococcosis

Indian Journal of Dermatology — Sun, 29 Oct 2006 22:56:02 +0100

We report here a human immunodeficiency virus positive patient who presented with MC like lesions. Disseminated cryptococcosis was confirmed by India ink preparation and histopathology. The condition of the patient improved with amphotercin B. (Source: Indian Journal of Dermatology)

Transgenic expression of the viral FLIP MC159 causes lpr/gld-like lymphoproliferation and autoimmunity.

Journal of Immunology — Thu, 26 Oct 2006 12:21:02 +0100

Authors: Woelfel M, Bixby J, Brehm MA, Chan FK Death receptor-induced programmed cell death (PCD) is crucial for the maintenance of immune homeostasis. However, interference of downstream death receptor signaling by genetic ablation or transgenic (Tg) expression of different apoptosis inhibitors often impairs lymphocyte activation. The viral FLICE (caspase-8)-like inhibitor proteins (v-FLIPs) are potent inhibitors of death receptor-induced apoptosis and programmed necrosis. We generated Tg mice expressing the v-FLIP MC159 from Molluscum contagiosum virus under the control of the H2Kb class I MHC promoter to examine the role of death receptor-induced PCD in the control of immune functions and homeostasis. We found that expression of MC159 led to lymphoproliferation and autoimmunity as e...

Unusual coexistence of molluscum contagiosum and verruca plana in a hyper–IgE syndrome

International Journal of Dermatology — Wed, 11 Oct 2006 13:44:43 +0100

International Journal of Dermatology Volume 45, Issue 10, Page 1199-1201, Oct 2006. (Source: International Journal of Dermatology)

Disseminated crytococcosis with extensive cutaneous involvement in AIDS

Indian Journal of Medical Microbiology — Wed, 11 Oct 2006 00:37:06 +0100

We present here a case of a 34 years old female with AIDS. She presented with multiple skin coloured umbilicated over face, neck, trunk and limbs, which mimicked molluscum contagiosum and kaposi sarcoma. The tissue from cutaneous lesions was collected by excision biopsy and processed by standard mycological methods. Cryptococcus neoformans was isolated and identified. Cerebrospinal fluid (CSF) also yielded the growth of C. neoformans . Cryptococcal antigen was detected with a titre of 1024 by Latex agglutination, is serum and CSF. Her serum was reactive for HIVI and 2 antibodies. The CD4 lymphocytes count was 80/cmm. The HIV viral load was 2,48,084 copies/mL. She was treated with amphotericin B ...

Giant molluscum contagiosum.

Indian Pediatrics — Mon, 18 Sep 2006 19:44:02 +0100

Authors: Pandhi D, Singhal A PMID: 15923699 [PubMed - indexed for MEDLINE] (Source: Indian Pediatrics)

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Ocular manifestations of molluscum contagiosum

Clinical and Experimental Optometry — Wed, 26 Jul 2006 07:35:35 +0100

Clinical and Experimental Optometry Volume 0, Issue 0, Page ???-???. (Source: Clinical and Experimental Optometry)

Topical treatment of molluscum contagiosum with imiquimod 5% cream in Turkish children

Pediatrics International — Tue, 25 Jul 2006 13:04:37 +0100

Pediatrics International Volume 48, Issue 4, Page 403-405, Aug 2006. (Source: Pediatrics International)

Molluscum contagiosum infection after reduced-intensity cord blood transplantation

Bone Marrow Transplantation — Mon, 19 Jun 2006 06:00:00 +0100

(Source: Bone Marrow Transplantation)

Double-Blind, Randomized, Placebo-Controlled Trial of the Use of Topical 10% Potassium Hydroxide Solution in the Treatment of Molluscum Contagiosum

Pediatric Dermatology — Mon, 12 Jun 2006 15:12:30 +0100

Pediatric Dermatology Volume 23, Issue 3, Page 279-281, May 2006 (Source: Pediatric Dermatology)

Interferon-{alpha} Treatment of Molluscum Contagiosum in a Patient With Hyperimmunoglobulin E Syndrome

PEDIATRICS — Thu, 01 Jun 2006 06:00:00 +0100

We report widely disseminated molluscum contagiosum that occurred in a 9-year-old boy secondary to hyperimmunoglobulin E syndrome, a primary immunodeficiency disorder. Cutaneous examination revealed numerous, widespread, skin-colored to translucent, firm, umbilicated papules of varying sizes. They were distributed throughout the perineal and gluteal areas and bilaterally over his lower limbs. A biopsy specimen from his skin lesion demonstrated lobulated epidermal growth that consisted of keratinocytes with large intracytoplasmic eosinophilic inclusion bodies and a central crater. These findings were consistent with the diagnosis of molluscum contagiosum. Many treatments for his skin lesions were ineffective, including physical destruction or manual extrusion of the lesions; cryotherapy; cu...

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Treatment of Molluscum Contagiosum with Topical Diphencyprone Therapy

Acta Dermato-Venereologica — Fri, 26 May 2006 06:00:00 +0100

(Source: Acta Dermato-Venereologica)

Unusual coexistence of molluscum contagiosum and verruca plana in a hyper–IgE syndrome

International Journal of Dermatology — Wed, 20 Jul 2005 20:24:05 +0100

International Journal of Dermatology Volume 0, Issue 0 (Source: International Journal of Dermatology)

Advances in antiviral therapy.

Dermatologic Clinics — Thu, 14 Apr 2005 06:00:00 +0100

Authors: Wu JJ, Pang KR, Huang DB, Tyring SK Infections with five of the herpesviruses (herpes simplex virus 1 [HSV-1], HSV-2, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus) are treated with topical or systemic antiviral therapies. There are more than 100 genotypes of human papillomaviruses (HPVs), which may manifest as warts, skin cancers, cervical cancer, anogenital cancers, and upper digestive tract cancers. Molluscum contagiosum (MC) is a common, benign viral infection of the skin. Immunomodulating agents, such as imiquimod, act on HPV and MC indirectly by inducing host immune responses, such as cytokines and cell-mediated immunity, and thereby reduce recurrences. There are multiple vaccines available for certain viral diseases and others in development for HSV-2 ...

Skin infections and ageing.

Ageing Research Reviews — Thu, 01 Jan 2004 07:00:00 +0100

Authors: Laube S Elderly individuals have an increased susceptibility to skin infections due to age-related anatomical, physiological and environmental factors. The types of organisms that cause primary skin and soft tissue infections are diverse, and include bacterial, viral and fungal pathogens as well as parasites. In the elderly, these infections and infestations may present with atypical signs and symptoms or may complicate underlying chronic skin disorders. Clinical features, investigations and management of the following important and common skin infections are described in more detail: cellulitis, erysipelas, necrotizing fasciitis, impetigo, folliculitis, furunculosis and carbunculosis, erythrasma, herpes zoster and postherpetic neuralgia, herpes simplex, warts, molluscum conta...

MedWorm: Molluscum Contagiosum

Atypical cutaneous lesions of

What Is Molluscum Contagiosum? What Causes Molluscum Contagiosum?

Molluscum contagiosum: Common skin infection spreads easily

Vertically Transmitted Molluscum Contagiosum Infection

Neonatal Molluscum Infections Likely Vertically Transmitted

Atypical cutaneous lesions of <i>Penicillium marneffei</i> infection as a manifestation of the immune reconstitution inflammatory syndrome after highly active antiretroviral therapy

[What's new in dermatological therapy?]

<i>Molluscum contagiosum </i> and dental caries: A pertinent combination

Mucocutaneous manifestations in 150 HIV-infected Indian patients and their relationship with CD4 lymphocyte counts

[Molluscum contagiosum: Descriptive study.]

Immune reconstitution inflammatory syndrome involving the skin

FLIP-mediated autophagy regulation in cell death control

Treatment for anogenital molluscum contagiosum.

Adult self-healing papular mucinosis on genital skin

Factors and outcome in BK virus nephropathy in a Hispanic kidney transplant population

Comparative Study on the Efficacy, Safety, and Acceptability of Imiquimod 5% Cream versus Cryotherapy for Molluscum Contagiosum in Children

Increased expression of human beta-defensin 3 in mollusca contagiosum

Rashes and Fever in Children: Sorting Out the Potentially Dangerous, Part 3

Topical calcineurin inhibitors compromise stratum corneum integrity, epidermal permeability and antimicrobial barrier function

Standard guidelines for electrosurgery with radiofrequency current

Disfiguring molluscum contagiosum in a HIV-positive patient responding to antiretroviral therapy

Necrotizing fasciitis caused by Cryptococcus neoformans in a patient with pemphigus vegetans

Original papers Usefulness of dermoscopy for diagnosing pearly penile papules

Immunosuppressants/rituximab/thalidomide: Ecthyma gangrenosum, molluscum contagiosum and fatal cerebral toxoplasmosis: case report

Confluent molluscum contagiosum covering the eyelids of an HIV-positive child

Immunosuppressants/rituximab/thalidomide: Ecthyma gangrenosum, molluscum contagiosum and fatal cerebral toxoplasmosis: case report.

Molluscum contagiosum involving an epidermoid cyst with xanthogranuloma-like reaction in an HIV-infected patient

Disfiguring molluscum contagiosum in a HIV-positive patient responding to antiretroviral therapy

Phenotype of atopic dermatitis subjects with a history of eczema herpeticum

Pimecrolimus: Molluscum contagiosum in a child: case report

Pimecrolimus: Molluscum contagiosum in a child: case report.

Molluscum contagiosum after eyebrow shaping: a beauty salon hazard

Detection of molluscum contagiosum virus gene transcripts by in situ hybridization

Molluscum contagiosum infestation in an epidermal cyst: still infectious?

Detection of viral DNA in nonlesional skin of patients with molluscum contagiosum and on environmental fomites

Multiple Epidermolytic Acanthomas Must Not be Confused with Genital Human Papillomavirus Infection.

Disseminated cryptococcosis in an HIV-negative patient.

Cantharidin Use Among Pediatric Dermatologists in the Treatment of Molluscum Contagiosum

Molluscum contagiosum: immunomorphological aspects of keratinocytes markers of differentiation and adhesion

Molluscum contagiosum arising in melanocytic nevus and in superficial spreading melanoma.

Intraoral molluscum contagiosum imitating a squamous-cell carcinoma in an immunocompetent person – case report and review of the literature

Intraoral molluscum contagiosum imitating a squamous-cell carcinoma in an immunocompetent person - case report and review of the literature.

Parental Satisfaction, Efficacy, and Adverse Events in 54 Patients Treated With Cantharidin for Molluscum Contagiosum Infection

Molluscum Contagiosum

An open, nonrandomized, comparative study of imiquimod 5% cream versus 10% potassium hydroxide solution in the treatment of molluscum contagiosum

Giant cutaneous horn

Sebaceous gland hyperplasia of the foreskin.

Congenital Molluscum Contagiosum: Report of Four Cases and Review of the Literature

Co-infection of molluscum contagiosum virus and cryptococcosis in the same skin lesion in a HIV-infected patient.

Curettage treatment for molluscum contagiosum: a follow-up survey study

Curettage treatment for molluscum contagiosum: a follow-up survey study.

Efalizumab: First report of molluscum contagiosum: case report

Efalizumab: First report of molluscum contagiosum: case report.

Anterior segment manifestations of human immunodeficiency virus/acquired immune deficiency syndrome

The epidemiology of Molluscum contagiosum in HIV-seropositive patients: a unique entity or insignificant finding?

Disseminated Giant Molluscum Contagiosum in a Patient with Idiopathic CD4+ Lymphocytopenia

Resolution of giant <i>Molluscum contagiosum</i> with antiretroviral therapy

Resolution of giant <i>Molluscum contagiosum</i> with antiretroviral therapy

Co-infection of molluscum contagiosum virus and cryptococcosis in the same skin lesion in a HIV-infected patient

An overview of molluscum contagiosum: a viral skin condition.

Methotrexate: Molluscum contagiosum in an elderly patient: case report

Methotrexate: Molluscum contagiosum in an elderly patient: case report.

Molluscum contagiosum in human immunodeficiency virus infected patients

Prominent eosinophilic intranuclear inclusions in melanocytes of a melanocytic nevus: the aftermath of an infection with molluscum contagiosum? A case report

One-Year Experience with Candida Antigen Immunotherapy for Warts and Molluscum

Etanercept/infliximab: Human papillomavirus infection (first report with etanercept) and molluscum contagiosum: 2 case reports

Etanercept/infliximab: Human papillomavirus infection (first report with etanercept) and molluscum contagiosum: 2 case reports.

Cutaneous pseudolymphoma associated with molluscum contagiosum: a case report

Expression of toll-like receptors in verruca and molluscum contagiosum.

[Epidemiology, clinical picture and treatment of molluscum contagiosum: literature review]

Pattern of non-venereal dermatoses of female external genitalia in South India.

[Childhood dermatosis in a dermatology clinic of a general university hospital in Spain.]

Molluscum contagiosum.

Pharmacokinetics and Safety of Imiquimod 5% Cream in the Treatment of Molluscum Contagiosum in Children

Genital HPV Lesions and Molluscum Contagiosum Occurring in Patients Receiving Anti-TNF-a Therapy

Developer of Novel Treatment for Molluscum Announces Naturopathix, Inc. Commercial Spin Off

Molluscum contagiosum

SKINSIGHT: Reflectance Confocal Microscopy of Molluscum Contagiosum

A-Z Molluscum Contagiosum