MedWorm: Anesthesia

Complications of surgical termination of pregnancy in obese versus nonobese women

Contraception — Thu, 09 Feb 2012 03:36:55 +0100

To compare the perioperative risks in obese and nonobese women undergoing surgical termination of pregnancy. Retrospective review of all patients who underwent ultrasound-guided pregnancy termination between 6 and 23 weeks' gestation from July 2007 to June 2010. All cases were performed by residents under the supervision of fellowship-trained family planning physicians. Complication rates, operative times and anesthesia times were compared between obese [body mass index (BMI) >30 kg/m2) and nonobese women (BMI (Source: Contraception)

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Major Study Finds Miscarriage Risk Higher for Nurses...

NurseZone.com Nursing News — Thu, 09 Feb 2012 02:39:58 +0100

January 27, 2012 - A recent study published by the American Journal of Obstetrics and Gynecology has found the rate of spontaneous abortion in nurses who handle chemotherapy drugs to be twice that in nurses who did not handle these drugs. Past studies have yielded similar results, but this study, done in partnership with National Institute for Occupational Safety and Health (NIOSH) and the Nurses’ Health Study 2, used a significantly larger sample size of nearly 7,000 nurse pregnancies. The study looked at five potentially hazardous exposures: x-rays, chemotherapy drugs, sterilizing agents, anesthetic gases and antiviral drugs. (Source: NurseZone.com Nursing News)

Impact of early reoperation after resection for colorectal cancer on long‐term oncological outcomes

Colorectal Disease — Wed, 08 Feb 2012 21:05:54 +0100

Conclusions Compared with non‐reoperated patients matched for patient, tumour and operative characteristics, patients reoperated in the early postoperative period have worse long‐term oncological outcomes. Adoption of strategies to reduce the risk of reoperation may be associated with the additional advantage of improved oncological outcomes in addition to the short‐term advantages. (Source: Colorectal Disease)

Rational Generalized Offsets of Rational Surfaces

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

The rational surfaces and their offsets are commonly used in modeling and manufacturing. The purpose of this paper is to present relationships between rational surfaces and orientation-preserving similarities of the Euclidean 3-space. A notion of a similarity surface offset is introduced and applied to different constructions of rational generalized offsets of a rational surface. It is shown that every rational surface possesses a rational generalized offset. Rational generalized focal surfaces are also studied. (Source: Anesthesiology Research and Practice)

Common Errors in Digital Panoramic Radiographs of Patients with Mixed Dentition and Patients with Permanent Dentition

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

Conclusions. More errors were prevalent in panoramic radiographs of permanent dentitions. Properly positioning the patient is the most important factor in preventing a cascade of errors. (Source: Anesthesiology Research and Practice)

Study on the Interaction between Two Hydrokinetic Savonius Turbines

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

Savonius turbine is simple in design and easy to fabricate at a lower cost. The drag is the basic driving force for Savonius turbine. Savonius turbines are mainly used for the small-scale electricity generation in remote areas. In real life, multiple Savonius turbines are to be arranged to form a farm to scale up the electricity generation. So, it is important to study the interaction among them to avoid the power loss due to negative interaction between turbines. The purpose of this investigation is to examine closely the effect of interaction between two Savonius turbines arranged in line. Experimental investigations are carried out to study the mutual interaction between turbines with water as the working medium at a Reynolds number of 1.2×105 based on the diameter of the turbine. ...

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Giant Cell Tumors of the Axial Skeleton

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

Conclusions. GCT of the axial skeleton have a high local recurrence rate. Neurological deficits are common. En-bloc spondylectomy combined with embolization is the treatment of choice. In case of inoperability, serial arterial embolization seems to be an alternative not only for sacral but also for spinal tumors. (Source: Anesthesiology Research and Practice)

Axisymmetric Stagnation Flow of a Micropolar Nanofluid in a Moving Cylinder

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

An analysis is carried out for axisymmetric stagnation flow of a micropolar nanofluid in a moving cylinder with finite radius. The coupled nonlinear partial differential equations of the problem are simplified with the help of similarity transformations and the resulting coupled nonlinear differential equations are solved analytically by homotopy analysis method (HAM). The features of the flow phenomena, inertia, heat transfer, and nanoparticles are analyzed and discussed. (Source: Anesthesiology Research and Practice)

Post-Communist Health Transitions in Central and Eastern Europe

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

The countries of Central and Eastern Europe (CEE) have gone through immense political and socioeconomic restructuring after the collapse of communism around 1990. Such transition has affected the lives of populations in these countries in many significant respects. A key aspect of life and wellbeing in any society is that of population health. This paper traces the transitions in population health—life expectancies and mortality rates for both males and females—in seven of the CEE countries during the two decades after the fall of communism. We estimate a series of panel data models to identify some of the common factors that would explain health transitions in these countries, while allowing for country-specific variability. Our findings indicate that the health transitions ar...

A Dysmorphic Child with a Pericentric Inversion of Chromosome 8

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

An 8-year-old boy was referred to our institute with dysmorphic features such as mild lupus, micrognathia, low hair line, hypoplasia, hemi atrophy of left side of the face, abnormal size of ears, hypothenar, hypoplasia of chin, and tongue tie. MRI scan was found to be normal and EEG suggestive of generalized seizure disorder. Cytogenetic evaluation of the proband revealed a pericentric inversion of chromosome 8 with 46, XY, and inv 8 (p11.2; q21.2) karyotype. (Source: Anesthesiology Research and Practice)

Neurogenic Bladder

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

Congenital anomalies such as meningomyelocele and diseases/damage of the central, peripheral, or autonomic nervous systems may produce neurogenic bladder dysfunction, which untreated can result in progressive renal damage, adverse physical effects including decubiti and urinary tract infections, and psychological and social sequelae related to urinary incontinence. A comprehensive bladder-retraining program that incorporates appropriate education, training, medication, and surgical interventions can mitigate the adverse consequences of neurogenic bladder dysfunction and improve both quantity and quality of life. The goals of bladder retraining for neurogenic bladder dysfunction are prevention of urinary incontinence, urinary tract infections, detrusor overdistension, and progressive upper ...

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Sensor Arrays and Electronic Tongue Systems

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

This paper describes recent work performed with electronic tongue systems utilizing electrochemical sensors. The electronic tongues concept is a new trend in sensors that uses arrays of sensors together with chemometric tools to unravel the complex information generated. Initial contributions and also the most used variant employ conventional ion selective electrodes, in which it is named potentiometric electronic tongue. The second important variant is the one that employs voltammetry for its operation. As chemometric processing tool, the use of artificial neural networks as the preferred data processing variant will be described. The use of the sensor arrays inserted in flow injection or sequential injection systems will exemplify attempts made to automate the operation of electronic ton...

Isolation of Human Islets for Autologous Islet Transplantation in Children and Adolescents with Chronic Pancreatitis

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

We present here a technical approach for the isolation and preservation of the islets proven to be efficient to obtain high numbers of islets, favoring the successful treatment of young patients. (Source: Anesthesiology Research and Practice)

Memantine as an Augmentation Therapy for Anxiety Disorders

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

Conclusion. The NMDA receptor antagonist memantine may be an effective augmentation therapy in patients with treatment-resistant anxiety. (Source: Anesthesiology Research and Practice)

Weighted ∂¯-Integral Representations of C1-Functions in C n

Anesthesiology Research and Practice — Wed, 08 Feb 2012 12:16:29 +0100

For C1-functions f, given in the complex space Cn, integral representations of the form f=P(f)−T(∂¯f) are obtained. Here, P is the orthogonal projector of the space L2{Cn;e−σ|z|ρ|z|γdm(z)} onto its subspace of entire functions and the integral operator T appears by means of explicitly constructed kernel Φ which is investigated in detail. (Source: Anesthesiology Research and Practice)

Neonatal administration with dexmedetomidine does not impair the rat hippocampal synaptic plasticity later in adulthood

Pediatric Anesthesia — Wed, 08 Feb 2012 12:08:52 +0100

Conclusion: These findings demonstrate that a single administration of DEX to rats on P7 preserves hippocampal synaptic plasticity as well as synaptic transmission later in life. In view of the some evidence that have demonstrated the permanent detrimental impact of commonly used anesthetics on neurological outcomes after neonatal exposure, our findings may suggest the relative safety of DEX administered as a sedative agent to neonatal animals with regard to the development of hippocampal synaptic functions. (Source: Pediatric Anesthesia)

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Ocular dryness excites two classes of corneal afferent neurons implicated in basal tearing in rats: involvement of transient receptor potential channels

Journal of Neurophysiology — Wed, 08 Feb 2012 05:00:00 +0100

This study reports the findings of two classes of corneal afferents excited by drying of the cornea (dry responses) in isoflurane-anesthetized rats: cold-sensitive (CS; 87%) and cold-insensitive (CI; 13%) neurons. Compared with CI neurons, CS neurons showed significantly higher firing rates over warmer corneal temperatures (~31–15°C) and greater responses to menthol, drying, and wetting of the cornea but lower responses when hyperosmolar solutions were applied to the ocular surface. We proposed that the dry responses of these corneal afferents derive from cooling and an increased osmolarity of the ocular surface, leading to the production of basal tears. An ocular application of the transient receptor potential channel TRPM8 antagonist BCTC (20 μM) decreased the dry responses ...

Analogic Launches Three New BK Medical Ultrasound Systems With Innovative Quantum Technology

Medical News (via PRIMEZONE) — Tue, 07 Feb 2012 20:30:00 +0100

BOSTON, Feb. 7, 2012 (GLOBE NEWSWIRE) -- Analogic Corporation (Nasdaq:ALOG), enabling the world's medical imaging and aviation security technology, today announced the worldwide launch of three BK Medical ultrasound systems, the Pro Focus(tm) UltraView 800, the Flex Focus(tm) 800, and the Flex Focus 500, each incorporating the groundbreaking Quantum(tm) technology. Significant new features and advancements from the Quantum Technology improve the practice of medicine by providing clinicians a faster and easier way to maximize ultrasound performance in urology, surgery, general imaging and anesthesiology. (Source: Medical News (via PRIMEZONE))

Comparison of forces applied to the maxillary incisors by direct and indirect laryngoscopes

Acta Anaesthesiologica Scandinavica — Tue, 07 Feb 2012 05:00:00 +0100

(Source: Acta Anaesthesiologica Scandinavica)

Drug‐administration sequence of target‐controlled propofol and remifentanil influences the onset of rocuronium. A double‐blind, randomized trial

Acta Anaesthesiologica Scandinavica — Tue, 07 Feb 2012 05:00:00 +0100

ConclusionThe onset time of rocuronium is prolonged significantly by early administration of remifentanil during target‐controlled infusion of propofol and remifentanil, and it may be due to the decreased CO caused by remifentanil. (Source: Acta Anaesthesiologica Scandinavica)

Vasopressors for the management of hypotension after spinal anesthesia for elective caesarean section. Systematic review and cumulative meta‐analysis

Acta Anaesthesiologica Scandinavica — Tue, 07 Feb 2012 05:00:00 +0100

ConclusionsOur analysis could clearly demonstrate a decreased risk of fetal acidosis associated with phenylephrine use. In addition with our findings for BE, this suggests a favorable effect of phenylephrine on fetal outcome parameters. The mechanism of pH depression is not related to pCO2. (Source: Acta Anaesthesiologica Scandinavica)

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Timing of skin testing after a suspected anaphylactic reaction during anaesthesia

Acta Anaesthesiologica Scandinavica — Tue, 07 Feb 2012 05:00:00 +0100

ConclusionsOnly positive skin tests can be taken into account, and there is little safety data to provide confidence in early skin testing. A protocol of how to act if urgent surgery is necessary is suggested. (Source: Acta Anaesthesiologica Scandinavica)

London Cancer New Drugs Group Rapid Review: SIRT WITH YTTRIUM-90 MICROSPHERES FOR THE THIRD LINE TREATMENT OF LIVER METASTASES FROM COLORECTAL CANCER

NeLM - Drug Specific Reviews — Tue, 07 Feb 2012 05:00:00 +0100

Source: London Cancer New Drugs Group Area: Evidence > Drug Specific Reviews Selective internal radiation therapy (SIRT; micro-brachytherapy or 'radio-embolisation') is used for the treatment of non-resectable hepatic metastases secondary to colorectal cancer, with limited or no extrahepatic disease. It may be used alone or in combination with chemotherapy. It aims to deliver radiation directly into the metastases, minimising the risk of radiation damage to healthy surrounding tissues. Under local anaesthesia, glass or resin microspheres containing a small radioactive source (yttrium-90) designed to embolise into small vessels around the metastases, are injected into branches of the hepatic artery (usually via a percutaneous femoral approach). In this way the microspheres can be selec...

Which dental local anaesthetics are latex-free?

NeLM - Medicines Q and A — Tue, 07 Feb 2012 05:00:00 +0100

Source: North West Medicines Information Centre Area: Evidence > Medicines Q & A Natural rubber latex (NRL) is present in many medical products, including disposable gloves, adhesive tape and bungs in medicine vials. People sensitised to NRL are at risk of developing allergic reactions, which can present with delayed symptoms such as a localised red itchy rash or with immediate symptoms such as itching of the skin and eyes, sneezing, bronchospasm or anaphylactic shock. People sensitised to NRL should avoid contact with all products that contain it, either in the product itself, in the packaging or introduced during the manufacturing process or storage. This Medicines Q&A provides a list of local anaesthetic preparations used in dentistry which are late...

Transcranial Doppler Pulsatility Index: What it is and What it Isn’t

Neurocritical Care — Mon, 06 Feb 2012 19:36:07 +0100

Conclusion TCD pulsatility index can be easily and quickly assessed but is usually misinterpreted as a descriptor of CVR. The mathematical model presents a complex relationship between PI and multiple haemodynamic variables. Content Type Journal ArticleCategory Original ArticlesPages 1-9DOI 10.1007/s12028-012-9672-6Authors Nicolás de Riva, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Hills Road, Box 167, Cambridge, CB2 0QQ UKKarol P. Budohoski, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Hills Road, Box 167, Cambridge, CB2 0QQ UKPeter Smielewski, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Ho...

Science Weekly podcast: Transplants and the future of intensive care

Guardian Unlimited Science — Mon, 06 Feb 2012 14:05:00 +0100

This week, we're focusing on some pivotal stories from the history of science and medicine. First up are human-to-human transplants and intensive care medicine. These are among the greatest successes of post-war medicine, but they also raise some of the most profound ethical questions. Ahead of a discussion at the Royal Institution in London, Kevin Fong, an anaesthetist and physiology lecturer at University College London, and medical historian Richard Barnett came into the studio to discuss how these important medical interventions started and, crucially, where they are heading. The debates will be held at the Royal Institution on 28 February. "From iron lungs to intensive care", "Hearts to hearts" will be on 15 February.The Observer's science editor, Robin McKie, was on hand to delve int...

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How To Boost The Power Of Pain Relief, Without Drugs

Health News from Medical News Today — Mon, 06 Feb 2012 09:00:00 +0100

Placebos reduce pain by creating an expectation of relief. Distraction - say, doing a puzzle - relieves it by keeping the brain busy. But do they use the same brain processes? Neuromaging suggests they do. When applying a placebo, scientists see activity in the dorsolateral prefrontal cortex. That's the part of the brain that controls high-level cognitive functions like working memory and attention - which is what you use to do that distracting puzzle. Now a new study challenges the theory that the placebo effect is a high-level cognitive function. The authors - Jason T. Buhle, Bradford L... (Source: Health News from Medical News Today)

Multiple Exposure To Anesthesia Increases Risk Of ADHD In Young Children

Health News from Medical News Today — Mon, 06 Feb 2012 08:00:00 +0100

Mayo Clinic researchers have found that multiple exposures to anesthesia at a young age are associated with higher rates of attention-deficit/hyperactivity disorder (ADHD). Children exposed to two or more anesthetics before age 3 had more than double the incidence of ADHD than children who had no exposure, says David Warner, M.D., a Mayo Clinic pediatric anesthesiologist and investigator on the observational study. The findings are published in Mayo Clinic Proceedings... (Source: Health News from Medical News Today)

Kids, Anesthesia, and ADHD

Medical Headlines From Ivanhoe.com — Mon, 06 Feb 2012 05:00:00 +0100

(Ivanhoe Newswire) -- Affecting three to five percent of children in the United States, attention deficit/hyperactivity disorder (ADHD) is the most diagnosed behavior disorder in childhood. (Source: Medical Headlines From Ivanhoe.com)

An intraoperative multimodal neurophysiologic approach to successful resection of precentral gyrus epileptogenic lesions

Epilepsia — Mon, 06 Feb 2012 05:00:00 +0100

We present an illustrative case of intractable epilepsy where judicious use of intraoperative neurophysiologic–techniques guided resection of precentral CD, under general anesthesia and in the absence of preoperative electrophysiologic mapping data. Ictal onset was accurately delineated using electrocorticography (ECoG). Phase reversal of the median somatosensory‐evoked potentials (MSSEPs) localized the central sulcus (CS). Motor evoked potentials (MEPs) triggered by high‐frequency monopolar anodal electrical cortical stimulation at the primary motor cortex (PMC) threshold delineated the PMC. Using this technique, PMC and the corticospinal tract (CST) were continuously monitored during resection. No changes in MEPs from the preresection baseline were seen; no residual abnormal activi...

Clonidine does not improve quality of ropivacaine axillary brachial plexus block in children

Pediatric Anesthesia — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion: Ropivacaine (0.2% 0.4 ml·kg−1) for ABPB provides sufficient postoperative analgesia in children scheduled for forearm or hand surgery. The addition of clonidine to ABPB does not improve overall postoperative analgesia but may increase the time to first analgesia request. (Source: Pediatric Anesthesia)

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Smartphone applications for pediatric anesthesia

Pediatric Anesthesia — Mon, 06 Feb 2012 05:00:00 +0100

We present a review of smartphone applications (apps) available for pediatric anesthesia. (Source: Pediatric Anesthesia)

An optimum time for intravenous cannulation after induction with sevoflurane in children

Pediatric Anesthesia — Mon, 06 Feb 2012 05:00:00 +0100

Conclusion: We recommend an optimal time of 3.5 min for attempting intravenous cannulation after the loss of eyelash reflex with sevoflurane induction. (Source: Pediatric Anesthesia)

Long-Term Efficacy of Deferasirox in Preventing Cardiovascular Complications in the Iron-Overloaded Gerbil

Journal of Cardiovascular Pharmacology and Therapeutics — Mon, 06 Feb 2012 05:00:00 +0100

Iron-induced cardiovascular disease is the leading cause of death in iron-overloaded patients. Deferasirox is a novel tridentate oral chelator that exhibits a half-life suitable for once-daily dosing; however, little is known regarding the effectiveness of this agent in preventing iron-induced cardiovascular disease. Adult male Mongolian gerbils were randomly divided into 3 groups: control, iron overload, and iron overload followed by deferasirox treatment. Iron-overloaded animals received iron dextran 100 mg/kg intraperitoneally (ip)/5 days for 10 weeks, while deferasirox was given 100 mg/kg per d orally (po) for 9 months post iron loading. Cardiac and aortic iron levels were determined by inductively coupled plasma atomic emission spectrometry. Gerbil electro- and echocardiograms were ob...

Remote ischaemic preconditioning reduces myocardial injury in patients undergoing heart valve surgery: randomised controlled trial

Heart — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions These data indicate that RIPC reduces myocardial injury and improves cardiac function in patients undergoing heart valve surgery. Trial registration number NCT01175681. (Source: Heart)

Anxiety and Pain as Predictors of Anesthesia Requirements Anxiety and Pain as Predictors of Anesthesia Requirements

Medscape Today Headlines — Mon, 06 Feb 2012 04:00:00 +0100

Can preoperative pain and anxiety predict anesthetic requirements and postoperative pain? British Journal of Anaesthesia (Source: Medscape Today Headlines)

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What Are the Major Diseases Involving Copper Metabolism?

PediatricEducation.org — Mon, 06 Feb 2012 00:08:49 +0100

Discussion Nutritional problems can occur in all parts of the world and in all socioeconomic strata. Caloric and/or protein inadequacy unfortunately plagues too many people because of inadequate supplies or availability. Supplemental food programs around the world attempt to provide appropriate nutrition, but can be stymied because of war, political instability, economic instability and many other social factors. The most common specific nutrient deficiencies are iron and Vitamin D deficiencies. Minerals important for essential nutrition include copper, iodine, selenium and zinc. A typical mixed diet usually provides enough minerals. In the United States, mineral deficiencies are usually uncommon unless there is an underlying disease process or abnormal food restrictions or diet. Vegan an...

Factors influencing blood loss and allogeneic blood transfusion practice in craniosynostosis surgery.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:50:07 +0100

Authors: Stricker PA, Fiadjoe JE, Jobes DR PMID: 22272672 [PubMed - in process] (Source: Paediatric Anaesthesia)

Delayed emergence from anesthesia in a child with congenital generalized lipodystrophy (Berardinelli-Seip syndrome).

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:49:56 +0100

Authors: Bennett T, Allford M PMID: 22272673 [PubMed - in process] (Source: Paediatric Anaesthesia)

Congenital tracheoesophageal fistula.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:49:45 +0100

Authors: Ho AM, Kwok WH PMID: 22272674 [PubMed - in process] (Source: Paediatric Anaesthesia)

Comment on the review article 'Anesthetic management of congenital tracheoesophageal fistula'.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:49:34 +0100

Authors: Sivaprakasam J, Guruswamy V, Bew S PMID: 22272675 [PubMed - in process] (Source: Paediatric Anaesthesia)

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Tracheal stenosis masquerading as decompensated total anomalous pulmonary venous return in a neonate.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:49:25 +0100

Authors: Demasie K, Humphreys L, Dierdorf SF PMID: 22272676 [PubMed - in process] (Source: Paediatric Anaesthesia)

25 years of experience, thousands of caudal blocks, and no dural puncture. What happened today?

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:49:16 +0100

Authors: Visoiu M, Lichtenstein S PMID: 22272677 [PubMed - in process] (Source: Paediatric Anaesthesia)

Spinal anesthesia in children - let's make it safe!

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:49:07 +0100

Authors: Goyal R, Shukla RN, Saxena V PMID: 22272678 [PubMed - in process] (Source: Paediatric Anaesthesia)

Paravertebral block for vascular ring operation in a patient with CHARGE syndrome.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:48:58 +0100

Authors: Türköz A, Can MG, Vuran C PMID: 22272679 [PubMed - in process] (Source: Paediatric Anaesthesia)

Children's seizures caused by continuous intravenous infusion of tramadol analgesia: two rare case reports.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:48:49 +0100

Authors: Li X, Zuo Y, Dai Y PMID: 22272680 [PubMed - in process] (Source: Paediatric Anaesthesia)

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Two case reports of the transverse cervical artery description under and below internal jugular veins in securing pediatric central venous catheters by ultrasound echo images.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:48:40 +0100

Authors: Kayashima K, Imai K, Sozen R PMID: 22272681 [PubMed - in process] (Source: Paediatric Anaesthesia)

A case report of an accidental vertebral arterial puncture videotaped during central venous catheterization in a child undergoing a ventricular septal defect repair.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:48:31 +0100

Authors: Kayashima K, Habe K PMID: 22272682 [PubMed - in process] (Source: Paediatric Anaesthesia)

Methemoglobinemia following prilocaine administration for bilateral tube thoracostomy in a pediatric case.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:48:21 +0100

Authors: Tunç M, Sazak H, Ulus F, Sahin S PMID: 22272683 [PubMed - in process] (Source: Paediatric Anaesthesia)

Study Looks At Reasons For Lack Of Improvement In Outcomes For Treatment Of Unruptured Brain Aneurysms

Health News from Medical News Today — Sat, 04 Feb 2012 08:00:00 +0100

Despite advances in the diagnosis and treatment of unruptured brain aneurysms, outcomes have remained stagnant over the last 10 years. This can be explained by the dramatic proliferation of minimally invasive endoscopic coiling procedures at lower-volume community hospitals, where outcomes are inferior. These findings are reported in a study by neurologists, neurosurgeons and neuro-anesthesiologists at NewYork-Presbyterian Hospital/Columbia University Medical Center and published in the journal Stroke... (Source: Health News from Medical News Today)

Multiple anesthesias linked to ADHD

Health News - UPI.com — Sat, 04 Feb 2012 05:03:33 +0100

ROCHESTER, Minn., Feb. 4 (UPI) -- Multiple exposures to anesthesia at a young age are associated with higher rates of attention-deficit hyperactivity disorder, U.S. researchers found. (Source: Health News - UPI.com)

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DIY science: should you try this at home?

Guardian Unlimited Science — Fri, 03 Feb 2012 22:59:00 +0100

When Richard Handl was arrested for attempting to split the atom on his stove, he joined a growing band of home experimenters cooking up all kinds of trouble behind the kitchen doorÄngelholm is a pretty southern Swedish town, famed for its clay cuckoo manufacturing, a clay cuckoo being a kind of ocarina, which is a kind of flute. The crime rate here is practically zero. Except one of its residents was last year arrested for trying to split the atom in his kitchen. His name is Richard Handl and he buzzes me into his first-floor flat.I wanted to meet Richard because I keep seeing reports of home science experimenters clashing with the authorities. There's been a spate of them this past year or two.I glance into Richard's kitchen and recognise his cooker from the news. It was horrendously, a...

Epidural Plus Fever in Mom May Raise Risks for Baby

The Doctors Lounge - Infections — Fri, 03 Feb 2012 20:00:00 +0100

Study found as mother's temperature rose, problems were more likely at birth (Source: The Doctors Lounge - Infections)

Anaesthetic use linked to ADHD

Telegraph Health — Fri, 03 Feb 2012 18:33:46 +0100

Children repeatedly exposed to anaesthetic early in life are more likely to develop Attention Deficit Hyperactivity Disorder (ADHD), an American study suggests. (Source: Telegraph Health)

Talin, Vinculin and Nestin Expression in Orofacial Muscles of Dystrophin Deficient mdx Mice

Archivum Immunologiae et Therapiae Experimentalis — Fri, 03 Feb 2012 17:10:48 +0100

Abstract The activity of cytoskeletal proteins like talin, vinculin and nestin increases in muscle that regenerates. Little is known about their role or at least their expression in the process of regeneration in masticatory muscles of mdx mice, a model of Duchenne muscular dystrophy. To determine a potential role of cytoskeletal proteins in the regeneration process of mdx masticatory muscles, we examined the expression of talin 1, talin 2, vinculin and nestin in 100-day-old control and mdx mice using quantitative RT-PCR, Western blot analyses and histochemistry. The protein expression of talin 1, talin 2, nestin and vinculin in mdx muscles remained unchanged as compared with normal mice. However, in mdx masseter it was found a relative increase of nestin compared to contr...

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Continuous Near-Infrared Regional Cerebral Perfusion Monitoring Shows Promise in Stroke Patients

Medgadget Anesthesiology — Fri, 03 Feb 2012 16:47:02 +0100

Researchers at Mayo Clinic in Florida have shown that cerebral optically-based near infra-red spectroscopic oximetry applied to patients who have suffered a stroke can help monitor regional cerebral perfusion in real time, and thus “may serve as a useful, noninvasive, bedside intensive care unit monitoring tool to assess brain oxygenation in a direct manner.” The study looked at the device called Fore-Sight from Casmed of Branford, CT, that measures blood oxygen, similar to a finger clip pulse oximeter. The Mayo study results have been published in Journal of Neurosurgery this month.Regional cerebral blood flow monitoring devices such as Fore-Sight are already in wide deployment in cardiac surgery, where they are thought to prevent brain ischemia in patients undergoing major s...

Children exposed to anaesthetic early in life 'have double risk of ADHD'

the Mail online | Health — Fri, 03 Feb 2012 15:57:52 +0100

Children given two or more doses of anaesthetic before they turned three had more than double the incidence of ADHD than children who had no exposure, Mayo Clinic research found. (Source: the Mail online | Health)

Study Suggests Surgical Breast Biopsy Not Overused

Health News from Medical News Today — Fri, 03 Feb 2012 08:00:00 +0100

Contrary to earlier findings, surgical breast biopsies may not be as overused as previously thought, according to a study in the February issue of the Journal of the American College of Radiology. Surgical breast biopsies are more invasive than needle biopsies, requiring an incision and the use of general anesthesia. Results from a previous study in 2011 in a surgical journal suggested that surgery is used for 30 percent of breast biopsies, an excessive number... (Source: Health News from Medical News Today)

Types and severity of operated supraclavicular brachial plexus injuries caused by traffic accidents

Acta Neurochirurgica — Fri, 03 Feb 2012 07:21:35 +0100

Conclusion Study results indicate that the most common injury was an upper plexus palsy. It was characteristic of bicycle accidents, and significantly more common in car and motorcycle accidents. The results also indicate that it is important to consider the potential of a brachial plexus injury after serious traffic accidents and to examine both upper extremities in detail even if some motor function is preserved. Content Type Journal ArticleCategory Clinical ArticlePages 1-5DOI 10.1007/s00701-012-1291-7Authors Radek Kaiser, Third Faculty of Medicine, Department of Neurosurgery, Hospital Kralovske Vinohrady, Charles University, Srobarova 50, 100 34 Prague, Czech RepublicPetr Waldauf, Third Faculty of Medicine, Department of Anesthesiology and Critical Care Medicin...

Renal bioenergetics during early gram-negative mammalian sepsis and angiotensin II infusion

Intensive Care Medicine — Fri, 03 Feb 2012 07:21:32 +0100

Conclusions During early hypotensive experimental Gram-negative sepsis, there was no evidence of renal bioenergetic failure despite decreased RBF. In this setting, the addition of a powerful renal vasoconstrictor does not lead to deterioration in renal bioenergetics. Content Type Journal ArticleCategory ExperimentalPages 1-8DOI 10.1007/s00134-012-2487-2Authors Clive N. May, Howard Florey Institute, Florey Neurosciences Institutes, University of Melbourne, Parkville, VIC, AustraliaKen Ishikawa, Howard Florey Institute, Florey Neurosciences Institutes, University of Melbourne, Parkville, VIC, AustraliaLi Wan, Howard Florey Institute, Florey Neurosciences Institutes, University of Melbourne, Parkville, VIC, AustraliaJohn Williams, Howard Florey Institute, Florey Neurosc...

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Brain Tissue Oxygenation and Cerebral Perfusion Pressure Thresholds of Ischemia in a Standardized Pig Brain Death Model

Neurocritical Care — Fri, 03 Feb 2012 07:21:15 +0100

Conclusions A severe increase of ICP leading to CPP below 30 mmHg and BtipO2 below 10 mmHg is associated with an increase of the L/P ratio, thus seems to be critical thresholds for cerebral ischemia under these conditions. Content Type Journal ArticleCategory Translational ResearchPages 1-8DOI 10.1007/s12028-012-9675-3Authors Karlis Purins, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Uppsala, SwedenPer Enblad, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Uppsala, SwedenLars Wiklund, Department of Surgical Sciences, Section of Anaesthesia and Intensive Care, Uppsala University, Uppsala, SwedenAnders Lewén, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Up...

Early versus late parenteral nutrition in the adult ICU: feeding the patient or our conscience?

Canadian Journal of Anaesthesia — Fri, 03 Feb 2012 05:00:00 +0100

Authors: Kerrie JP, Bagshaw SM, Brindley PG PMID: 22302305 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)

Evaluation of TAPSE as a measure of right ventricular output.

Canadian Journal of Anaesthesia — Fri, 03 Feb 2012 05:00:00 +0100

CONCLUSION: Tricuspid annular plane systolic excursion by M mode and by speckle tracking correlates modestly with SV. There was no correlation between TAPSE and SV by tissue tracking at the inferior wall of the right ventricle. Tricuspid annular plane systolic excursion by M mode and by speckle tracking does not track changes in SV following either volume loading or ephedrine administration. PMID: 22302303 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)

Joint immobilisation prevents murine osteoarthritis, and reveals the highly mechanosensitive nature of protease expression in vivo

Arthritis and Rheumatism — Fri, 03 Feb 2012 05:00:00 +0100

Conclusion: Gene expression in the joint following induction of OA is rapid and highly mechanosensitive. Regulated genes include the known pathogenic protease Adamts5. Targeting the mechanosensing mechanisms of joint tissues could offer new strategies for disease modification. (Source: Arthritis and Rheumatism)

Anesthesia in Toddlers Linked to ADHD (CME/CE)

MedPage Today Neurology — Thu, 02 Feb 2012 23:43:06 +0100

(MedPage Today) -- Children exposed to general anesthesia multiple times during the first two years of life have an increased likelihood of later developing attention deficit hyperactivity disorder, researchers found. (Source: MedPage Today Neurology)

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Anesthesia Exposure Linked To ADHD In Children

Health News from Medical News Today — Thu, 02 Feb 2012 22:00:00 +0100

A study by researchers at Mayo Clinic, Rochester Minn., and published in Mayo Clinic Proceedings, reveals that children who have been under anesthesia many times when they are young have a greater risk of developing attention-deficit/hyperactivity disorder (ADHD). According to David Warner, M.D, a Mayo Clinic pediatric anesthesiologist, and researchers of this study, kids who have been exposed to anesthesia more than twice before the age of 3 are twice as likely to have ADHD than children who have not been exposed... (Source: Health News from Medical News Today)

Anesthesia in Toddlers Linked to ADHD (CME/CE, with video)

MedPage Today Psychiatry — Thu, 02 Feb 2012 20:59:54 +0100

Cardinal Health Releases Smart-Seal Surgical Mask

Medgadget Anesthesiology — Thu, 02 Feb 2012 19:11:23 +0100

Cardinal Health has made available its Smart-Seal surgical mask that improves both its fit and reduces interior fogging while providing a high level of filtration and resistance to liquids.From the announcement:Read More (Source: Medgadget Anesthesiology)

Anesthetic Management of Direct Laryngoscopy and Dilatation of Subglottic Stenosis in a Patient with Severe Myasthenia Gravis

Advances in Pharmacological Sciences — Thu, 02 Feb 2012 18:35:24 +0100

We describe the anesthetic management of a patient with severe myasthenia gravis and tracheal stenosis; the patient was scheduled for direct laryngoscopy and dilatation. The combination of myasthenia gravis and tracheal obstruction presents several difficulties for anesthetic management. The airway is shared; therefore, any complications are also shared by the anesthesiologist and bronchoscopists. The potential for respiratory compromise in patients undergoing the two procedures requires that anesthesiologists be familiar with the underlying disease state, as well as the interaction of anesthetic and nonanesthetic drugs in a case involving myasthenia gravis. We reviewed the literature and report our experience in this case. There is no strong evidence for choosing one approach to general a...

Apolipoprotein E e4 allele does not increase the risk of early postoperative delirium after major surgery

Journal of Anesthesia — Thu, 02 Feb 2012 18:14:05 +0100

Conclusions Apolipoprotein e4 carrier status was not associated with an increased risk for early postoperative delirium. Age, congestive heart failure, and emergency surgery were independent risk factors for the development of delirium after major surgery. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00540-012-1326-5Authors Fernando José Abelha, Anesthesiology and Perioperative Care Unit, Surgical Department, Faculty of Medicine, University of Porto, Porto, PortugalVera Fernandes, Department of Anesthesiology, Centro Hospitalar de São João, Porto, PortugalMiguela Botelho, Department of Anesthesiology, Centro Hospitalar de São João, Porto, PortugalPatricia Santos, Department of Anesthesiology, Centro Hospitalar de São João, Porto,...

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Retrograde intubation during laryngeal cleft repair on cardiopulmonary bypass

Journal of Anesthesia — Thu, 02 Feb 2012 18:14:03 +0100

We present our experience of retrograde intubation for a 4-month-old patient who presented for laryngeal cleft repair on cardiopulmonary bypass. This case highlights the unique place for retrograde intubation in small patients in the current era. Content Type Journal ArticleCategory Clinical ReportPages 1-2DOI 10.1007/s00540-011-1310-5Authors Vincent Collard, Montreal Childrens Hospital, 2300 Tupper Street, Montreal, QC H3H 1P3, CanadaLeal G. Segura, Department of Anesthesiology, Perioperative and Pain Medicine, Children’s Hospital Boston, 300 Longwood Avenue, Bader 3, Boston, MA 02115, USADima G. Daaboul, Department of Anesthesiology, Perioperative and Pain Medicine, Children’s Hospital Boston, 300 Longwood Avenue, Bader 3, Boston, MA 02115, USAKoichi Yuki, Department of Anes...

Contrast-induced acute kidney injury: what is the prevalence of prevention protocols?

Intensive Care Medicine — Thu, 02 Feb 2012 18:13:11 +0100

Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00134-012-2479-2Authors Jamie M. Strachan, Intensive Care Unit, Royal Berkshire Hospital, Reading, RG1 5AN UKMichael P. J. DeVile, Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford, OX3 9DU UK Journal Intensive Care MedicineOnline ISSN 1432-1238Print ISSN 0342-4642 (Source: Intensive Care Medicine)

Clinicopathological Profile, Airway Management, and Outcome in Huge Multinodular Goiters: An Institutional Experience from an Endemic Goiter Region

World Journal of Surgery — Thu, 02 Feb 2012 18:12:35 +0100

Conclusions Long-standing huge goiters are common in iodine-deficient endemic areas. The majority of patients have symptomatic or clinicoradiological evidence of airway involvement. The incidence of RSE, airway deformity, intubation difficulty, and tracheomalacia is high with huge goiters. The surgery is technically demanding with greater associated chances of injury to native structures. Malignancy influences the presentation and outcome in smaller goiters. In centers with experienced endocrine surgeons and dedicated anesthetists, huge goiters can be successfully managed with minimal short-term and long-term morbidity. Content Type Journal ArticlePages 1-6DOI 10.1007/s00268-012-1447-xAuthors Amit Agarwal, Department of Endocrine Surgery, Sanjay Gandhi Post Gradua...

Sepsis Immunopathology: Perspectives of Monitoring and Modulation of the Immune Disturbances

Archivum Immunologiae et Therapiae Experimentalis — Thu, 02 Feb 2012 18:11:05 +0100

Abstract Septic syndromes are the main cause of death in the intensive care units and although the mortality rates is slowly decreasing, the occurrence of the disease has been increasing. The pathogenesis of sepsis includes countless disturbances of the host immune system starting with a harmful, infection-triggered exaggerated inflammatory cascade, followed by the development of an immunoparalysis state. The latter contributes to the failure in pathogen eradication and leads to secondary infections, which are often the cause of fatal complications. In this review, we consider different novel therapeutic strategies for restoration of immune function. The use of glucocorticoids, intravenous immunoglobulins, heparin, recombinant human activated protein C, granulocyte macroph...

The burden of endoscopic retrograde cholangiopancreatography (ERCP) performed with the patient under conscious sedation

Surgical Endoscopy — Thu, 02 Feb 2012 18:07:54 +0100

Conclusion One-third to one-half of patients experience pain and discomfort during and immediately after ERCP when it is performed with conscious sedation for the patient. Other sedation strategies, such as the use of general anesthesia or propofol, may well reduce the burden of ERCP, particularly for patients with a higher EQ-5D score, younger age, or therapeutic ERCP treatment. However, randomized trials are warranted. Content Type Journal ArticlePages 1-7DOI 10.1007/s00464-012-2162-2Authors S. M. Jeurnink, Department of Gastroenterology and Hepatology, University Medical Center, P.O. Box 85500, 3508 GA Utrecht, The NetherlandsE. W. Steyerberg, Department of Public Health, Erasmus MC/University Medical Center, Rotterdam, The NetherlandsE. J. Kuipers, Department o...

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Anti-Xa Levels 4 h After Subcutaneous Administration of 5,700 IU Nadroparin Strongly Correlate with Lean Body Weight in Morbidly Obese Patients

Obesity Surgery — Thu, 02 Feb 2012 17:58:24 +0100

Abstract Background Morbidly obese patients (BMI > 40 kg/m2) are at increased risk for venous thromboembolism, especially after surgery. Despite limited evidence, morbidly obese patients are often administered a double dose of nadroparin for thromboprophylaxis compared to non-obese patients. The aim of this study was to evaluate the influence of different body size descriptors on anti-Xa levels after a double dose of nadroparin (5,700 IU) in morbidly obese patients. Methods In 27 morbidly obese patients with a mean total body weight of 148 kg (range 107–260 kg), anti-Xa levels were determined peri-operatively until 24 h after administration of a subcutaneous dose of 5,700 IU of nadroparin. Results &nbs...

Prolonged propriospinal myoclonus following spinal anesthesia for cesarean section: case report and literature review

Archives of Gynecology and Obstetrics — Thu, 02 Feb 2012 17:57:19 +0100

Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00404-012-2246-1Authors Anna Lev, Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center, POB 3235, 91031 Jerusalem, IsraelIsabell Korn-Lubezki, Department of Neurology, Shaare Zedek Medical Center, Jerusalem, IsraelBettina Steiner-Birmanns, Department of Neurology, Shaare Zedek Medical Center, Jerusalem, IsraelArnon Samueloff, Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, IsraelYaakov Gozal, Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zedek Medical Center, POB 3235, 91031 Jerusalem, IsraelAlexander Ioscovich, Department of Anesthesiology, Perioperative Medicine and Pain Treatment, Shaare Zede...

Young Children Exposed to Anesthesia Multiple Times Show Elevated Rates of ADHD

Mayo Clinic Research News — Thu, 02 Feb 2012 17:40:21 +0100

Anesthesia in Early Childhood May Be Linked to ADHD

Pediatrics News - Doctors Lounge — Thu, 02 Feb 2012 15:00:00 +0100

Only associated with multiple surgeries; not a reason to delay needed procedures, experts say (Source: Pediatrics News - Doctors Lounge)

Young children exposed to anesthesia multiple times show elevated rates of ADHD

ScienceDaily Headlines — Thu, 02 Feb 2012 14:22:22 +0100

Researchers have found that multiple exposures to anesthesia at a young age are associated with higher rates of attention-deficit/hyperactivity disorder (ADHD). (Source: ScienceDaily Headlines)

30 Years Lost in Anesthesia Theory

Thu, 02 Feb 2012 14:05:42 +0100

(Source: Cardiovascular and Hematological Agents in Medicinal Chemistry (Formerly Current Medicinal Chemistry - Cardiovascular and Hematological Agents))

Anesthesia in Early Childhood May be Linked to ADHD

MedlinePlus Health News — Thu, 02 Feb 2012 14:00:00 +0100

Only associated with multiple surgeries; not a reason to delay needed procedures, experts say Source: HealthDay Related MedlinePlus Pages: Anesthesia, Attention Deficit Hyperactivity Disorder, Children's Health (Source: MedlinePlus Health News)

General anesthesia in infancy linked to higher risk of ADHD

CNN.com - Health — Thu, 02 Feb 2012 12:31:58 +0100

Infants who undergo surgical procedures requiring general anesthesia in their first two years of life may be at increased risk of developing ADHD. (Source: CNN.com - Health)

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Automatic electroencephalography monitor offers tight anesthesia control

MedWire News - Anesthesiology — Thu, 02 Feb 2012 12:16:26 +0100

An automatic system that monitors patients’ needs for anesthesia and analgesia during surgery outperforms manual control of anesthesia on some indices, research shows. (Source: MedWire News - Anesthesiology)

The Size 1 ProSeal™ laryngeal mask airway in infants: a randomized, noncrossover study with the Classic™ laryngeal mask airway

Pediatric Anesthesia — Thu, 02 Feb 2012 12:09:21 +0100

Conclusions: We conclude that the size 1 PLMA is a stable, safe, and efficacious airway control device during neonatal and infant anesthesia, allowing higher peak airway pressure during positive pressure ventilation, with fewer mask displacements and gastric insufflations than the cLMA. (Source: Pediatric Anesthesia)

Helping Seniors With Pain: New GSA Resources

Health News from Medical News Today — Thu, 02 Feb 2012 09:00:00 +0100

The pain suffered by older adults is the shared focus of the two newest entries in The Gerontological Society of America's (GSA) From Publication to Practice* series. Together they address both pain management and new labeling changes for one of the most popular pain medications, acetaminophen. Both issues aim to provide readers with information on how new advances in pain prevention, treatment, and management may improve care and quality of life for older adults... (Source: Health News from Medical News Today)

Researchers Develop Novel Drug Delivery System

Health News from Medical News Today — Thu, 02 Feb 2012 08:00:00 +0100

Long duration, controllable drug delivery is of wide interest to medical researchers and clinicians, particularly those seeking to improve treatment for patients with chronic pain or to prevent cancer recurrence after surgery. Now a team of researchers led by Boston University Biomedical Engineer and Chemist Mark Grinstaff has developed a unique material and drug delivery mechanism that could pave the way for implants that release a drug at a designated rate for months... (Source: Health News from Medical News Today)

Anesthesia in Early Childhood May Be Linked to ADHD

MedicineNet Kids Health General — Thu, 02 Feb 2012 07:00:00 +0100

Title: Anesthesia in Early Childhood May Be Linked to ADHDCategory: Health NewsCreated: 2/2/2012 10:05:00 AMLast Editorial Review: 2/2/2012 (Source: MedicineNet Kids Health General)

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Intraoperative blood pressure changes as a risk factor for anastomotic leakage in colorectal surgery

International Journal of Colorectal Disease — Thu, 02 Feb 2012 06:54:30 +0100

Conclusions The development of an anastomotic leakage after colorectal surgery is related to surgical, patient and anaesthetic risk factors. A high preoperative diastolic blood pressure and profound intraoperative hypotension combined with complex surgery, marked by a blood loss of ≥250 mL and the occurrence of intraoperative adverse events, is associated with an increased risk of developing anastomotic leakage. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00384-011-1381-7Authors I. L. Post, Department of Anesthesiology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The NetherlandsP. M. Verheijen, Department of Surgery, Diakonessenhuis Hospital, Utrecht, the NetherlandsA. Pronk, Department of Surgery, Diakonessenhu...

Visualization versus Neuromonitoring of Recurrent Laryngeal Nerves during Thyroidectomy: What About the Costs?

World Journal of Surgery — Thu, 02 Feb 2012 06:53:59 +0100

Conclusions The regional DRG tariff for thyroid surgery is barely sufficient to cover conventional surgery costs. Intraoperative neural monitoring accounts for 5–7% of the hospitalization costs for a thyroidectomy. Content Type Journal ArticlePages 1-7DOI 10.1007/s00268-012-1452-0Authors Gianlorenzo Dionigi, Department of Surgical Sciences, Endocrine Surgery Research Center, University of Insubria Varese-Como, Via Guicciardini, 21100 Varese, ItalyAlessandro Bacuzzi, Department of Anesthesia, University of Insubria, 21100 Varese, ItalyLuigi Boni, Department of Surgical Sciences, Endocrine Surgery Research Center, University of Insubria Varese-Como, Via Guicciardini, 21100 Varese, ItalyStefano Rausei, Department of Surgical Sciences, Endocrine Surgery Research Center...

Comparison of Dexamethasone with Ondansetron or Haloperidol for Prevention of Patient-Controlled Analgesia-Related Postoperative Nausea and Vomiting: A Randomized Clinical Trial

World Journal of Surgery — Thu, 02 Feb 2012 06:53:57 +0100

Conclusions Dexamethasone 5 mg with either haloperidol 2 mg or ondansetron 4 mg provides a better antiemetic effect than dexamethasone 5 mg alone in patients receiving postoperative morphine PCA. Content Type Journal ArticlePages 1-7DOI 10.1007/s00268-012-1446-yAuthors Po-Kai Wang, Department of Anesthesiology, Buddhist Tzu-Chi General Hospital, 707, Section 3, Chung-Yang Road, 970, Hualien, Taiwan, R.O.CPei-Jiuan Tsay, Department of Anesthesiology, Buddhist Tzu-Chi General Hospital, 707, Section 3, Chung-Yang Road, 970, Hualien, Taiwan, R.O.CChia-Chun Huang, Department of Anesthesiology, Buddhist Tzu-Chi General Hospital, 707, Section 3, Chung-Yang Road, 970, Hualien, Taiwan, R.O.CHsien-Yong Lai, Department of Medical Education and Research, M...

Anesthesia may cause ADHD and Brain Damage

NaturalNews.com — Thu, 02 Feb 2012 06:00:00 +0100

Many within the alternative health community believe anesthetics cause brain damage. Evidence for this claim has included innumerable animal studies demonstrating a wide range of side effects from every class of anesthetics. Clinical observations of patients and in... (Source: NaturalNews.com)

Young children exposed to anesthesia multiple times show elevated rates of ADHD

EurekAlert! - Medicine and Health — Thu, 02 Feb 2012 05:00:00 +0100

(Mayo Clinic) Mayo Clinic researchers have found that multiple exposures to anesthesia at a young age are associated with higher rates of attention-deficit/hyperactivity disorder. (Source: EurekAlert! - Medicine and Health)

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A toothbrush impalement injury of the floor of mouth in autism child

Dental Traumatology — Thu, 02 Feb 2012 05:00:00 +0100

We report a case of a toothbrush impalement injury of the floor of the mouth in a child with autism. A 5‐year‐old boy with autism presented with an accidentally impaled toothbrush in the oral cavity. He was taken to the operation room and examined under general anesthesia. The handle of the toothbrush was cut off using rib scissors for mask ventilation, and intra‐oral intubation was performed. The toothbrush was located approximately 2.5 cm into the floor of the mouth. The toothbrush was removed uneventfully. Intravenous antibiotic therapy was instituted during hospitalization, and discharge from the hospital occurred 4 days after the operation. (Source: Dental Traumatology)

Tracheal occlusions evoke respiratory load compensation and neural activation in anesthetized rats

Journal of Applied Physiology — Thu, 02 Feb 2012 05:00:00 +0100

Airway obstruction in animals leads to compensation and avoidance behavior and elicits respiratory mechanosensation. The pattern of respiratory load compensation and neural activation in response to intrinsic, transient, tracheal occlusions (ITTO) via an inflatable tracheal cuff are unknown. We hypothesized that ITTO would cause increased diaphragm activity, decreased breathing frequency, and activation of neurons within the medullary and pontine respiratory centers without changing airway compliance. Obstructions were performed for 2–3 breaths followed by a minimum of 15 unobstructed breaths with an inflatable cuff sutured around the trachea in rats. The obstruction procedure was repeated for 10 min. The brains of obstructed and control animals were removed, fixed, sectioned, and st...

A recurrent variant branch of the inferior alveolar nerve: Is it unique?

Clinical Anatomy — Thu, 02 Feb 2012 05:00:00 +0100

In this study, a recurrent variant branch of the IAN arising just below the origin of the mylohyoid nerve was investigated in adult Indian cadavers allotted for dissection to the first year dental students of Government Dental College, Ahmedabad (India). The dissection was performed by the lateral approach to the infratemporal fossa. The nerve was found in 12 of 35 sides (34.3%) and 8 of 18 cadavers (44.4%). Thus, in our study it was not a rare variation of the IAN, where in most cases it innervated the lateral pterygoid muscle. In some cases, it terminated in the lateral pterygoid muscle. In others, it penetrated the muscle to join the anterior or posterior division of the mandibular nerve or its branches; thus, the variant nerve in such cases might be regarded as an additional root of th...

Ursodeoxycholate modulates bile flow and bile salt pool independently from the cystic fibrosis transmembrane regulator (Cftr)in mice.

American Journal of Physiology. Gastrointestinal and Liver Physiology — Thu, 02 Feb 2012 05:00:00 +0100

Conclusion. Acute TUDCA infusion and chronic UDCA treatment both stimulate bile flow in CF conditions independently from Cftr function. Chronic UDCA treatment reduces the hydrophobicity of the bile salt pool in Cftr(-/-) mice. These results support a potential beneficial effect of UDCA on bile flow and bile salt metabolism in CF conditions. PMID: 22301109 [PubMed - as supplied by publisher] (Source: American Journal of Physiology. Gastrointestinal and Liver Physiology)

[PHTLS team course: a pilot project : Structured student education in prehospital care of severely injured patients.]

Der Unfallchirurg — Thu, 02 Feb 2012 05:00:00 +0100

CONCLUSION: Especially the treatment of multiply injured patients is a challenge for young medical professionals. However, there is a high motivation to learn and train in emergency medicine. The students long for a practical trauma course compared to the advanced medical CPR course provided by the Department of Anaesthesiology of the University of Heidelberg. Those algorithm-based trauma courses do exist with PHTLS® and ATLS®. Based on these courses we developed the PHTLS® TEAM course. PMID: 22294422 [PubMed - as supplied by publisher] (Source: Der Unfallchirurg)

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Massages Scientifically Proven To Help Reduce Pain

Health News from Medical News Today — Wed, 01 Feb 2012 23:00:00 +0100

According to a study published online in Science Translational Medicine by researchers from the Buck Institute for Research on Aging and McMaster University in Hamilton Ontario, massages aid the growth of new mitochondria in skeletal muscle, and help to reduce inflammation. Many athletes would attest to the fact that massages help in treating pain, and speed up recovery, but now scientists have the evidence to go along with their testimonies... (Source: Health News from Medical News Today)

Alternative model of birth to reduce the risk of assisted vaginal delivery and perineal trauma

International Urogynecology Journal — Wed, 01 Feb 2012 17:14:21 +0100

Conclusion A combination of postural changes during the passive expulsive phase of labor and lateral position during active pushing time is associated with reductions in AVD and PT. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00192-012-1675-5Authors Carolina Walker, Department of Physiotherapy, European University of Madrid, c/ Villaviciosa de Odón s/n, 28260 Madrid, SpainTania Rodríguez, Department of Physiotherapy, European University of Madrid, c/ Villaviciosa de Odón s/n, 28260 Madrid, SpainAna Herranz, Department of Obstetrics and Gynecology, La Paz University Hospital, Madrid, SpainJosé A. Espinosa, Department of Obstetrics and Gynecology, Quiron University Hospital, Madrid, SpainEmília Sánchez, Blanquerna School of Health S...

Treatment of Neurocritical Care Emergencies in Pregnancy

Current Treatment Options in Neurology — Wed, 01 Feb 2012 17:14:15 +0100

Opinion statement Neurologic emergencies are a major cause of morbidity and mortality in pregnant women. In part because the patient population is young, the nihilistic approach that often accompanies neurologically devastating disorders in other contexts is largely absent. A number of studies have demonstrated improved patient outcomes in the setting of aggressive care delivered by neurointensivists in a specialty-specific environment. It stands to reason that young, pregnant women who suffer from neurologically devastating disorders and who have a wide range of prognosis may also benefit from such specialized care. Close collaboration between obstetricians and neurointensivists is critical in this context. A number of unique considerations in diagnosis and management pre...

Delay from fracture to hospital admission: a new risk factor for hip fracture mortality?

Osteoporosis International — Wed, 01 Feb 2012 17:14:09 +0100

Conclusions If the association estimated in our study is causal, our results provide evidence that some hip fracture-related deaths could be prevented by improved patient access to appropriate and timely hospital care in the context of a developing country. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-012-1917-xAuthors E. I. O. Vidal, Internal Medicine Department, Universidade Estadual Paulista (UNESP), Botucatu, BrazilD. C. Moreira-Filho, Preventive and Social Medicine Department, Universidade Estadual de Campinas (UNICAMP), Campinas, BrazilR. S. Pinheiro, Public Health Studies Institute, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, BrazilR. C. Souza, Health Sciences Center, Fundação Serra dos Órgãos, Teresop...

Bilateral Single Sitting Myringoplasty Using Tragal Cartilage from One Ear

Indian Journal of Otolaryngology and Head and Neck Surgery — Wed, 01 Feb 2012 17:13:59 +0100

Abstract Though single sitting myringoplasty using temporalis fascia under general anesthesia has been documented in many studies, but ours is the first center to have started using tragal cartilage harvested from one ear to do bilateral myringoplasty in one sitting using local anesthesia with excellent results including very good graft uptake rate and audiological improvement without significant complications. Content Type Journal ArticleCategory Short CommunicationPages 1-4DOI 10.1007/s12070-012-0487-8Authors Arvinder Singh Sood, Department of ENT, SGRDIMSR, 22-A, Rajinder Nagar, Sultanwind Road, Amritsar, 143001 India Journal Indian Journal of Otolaryngology and Head & Neck SurgeryOnline ISSN 0973-7707Print ISSN 2231-3796 (Source: Indian Journal of Otolaryngo...

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Toluidine blue for the intraoperative staining of the ureters. Studies on the safe administration in rats

Langenbeck's Archives of Surgery — Wed, 01 Feb 2012 17:11:57 +0100

Conclusions In rats, intravenous injection of 0.4 mg TB/kg was sufficient for the intraoperative staining of the urinary tract without the risk of severe cardiovascular and hemodynamic side effects. Provided our results are transferable to humans, the administration of low TB doses could allow its safer clinical use for the intraoperative visualization of the ureters. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00423-012-0907-yAuthors Frank Petrat, Institut für Physiologische Chemie, Universitätsklinikum, Universität Duisburg-Essen, Hufelandstr. 55, 45122 Essen, GermanyMatthias Hartmann, Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen, Hufelandstr. 55, 45122 Essen, GermanyErnst Schmidt, Dr. F...

Re: The efficacy and safety of ureteroscopy for ureteral calculi in pregnancy: our experience in 32 patients

Urological Research — Wed, 01 Feb 2012 17:11:43 +0100

Content Type Journal ArticleCategory Letter to the EditorPages 1-1DOI 10.1007/s00240-012-0458-2Authors Abdulkadir Tepeler, Department of Urology, Faculty of Medicine, Bezmialem Vakif University, Adnan Mendres Bulvarı, Fatih, Istanbul, TurkeyAbdullah Armağan, Department of Urology, Faculty of Medicine, Bezmialem Vakif University, Adnan Mendres Bulvarı, Fatih, Istanbul, TurkeyZafer Doğan, Department of Anesthesiology, Faculty of Medicine, Bezmialem Vakif University, Istanbul, TurkeyMehmet Yılmaz, Department of Obstetrics and Gynecology, Faculty of Medicine, Atatürk University, Erzurum, TurkeyMesrur Selçuk Sılay, Department of Urology, Faculty of Medicine, Bezmialem Vakif University, Adnan Mendres Bulvarı, Fatih, Istanbul, Turkey Journal Urological ResearchOnline ISSN 1434...

Pseudocholinesterase in gestational diabetes: positive correlation with LDL and negative correlation with triglyceride

Archives of Gynecology and Obstetrics — Wed, 01 Feb 2012 17:10:04 +0100

Conclusion PChE activity was not significantly different between the groups. However, there was a positive correlation between PChE and LDL levels in pregnant women with GD, suggesting that LDL levels in pregnant women with GD may help to predict the risk of prolonged apnea in situations in which PChE activity cannot be measured. Content Type Journal ArticleCategory Maternal-Fetal MedicinePages 1-7DOI 10.1007/s00404-012-2241-6Authors Lütfiye Pirbudak Cocelli, Department of Anaesthesiology and Algology, Medical School, University of Gaziantep, 27310 Gaziantep, TurkeyEbru Dikensoy, Department of Obstetrics and Gynecology, Medical School, University of Gaziantep, Gaziantep, TurkeyHülya Cicek, Department of Clinical Biochemistry, Medical School, University of Gaziante...

Deep sedation during pneumatic reduction of intussusception

Pediatric Radiology — Wed, 01 Feb 2012 17:09:45 +0100

Conclusions Deep sedation with propofol did not add any complication to the pneumatic reduction. The fluoroscopic time was short. The success rate of reduction was high, raising the possibility that sedation is beneficial, possibly by smooth muscle relaxation. Content Type Journal ArticleCategory Original ArticlePages 1-4DOI 10.1007/s00247-011-2311-0Authors Anat Ilivitzki, Department of Diagnostic Imaging, Rambam Health Care Campus, Haifa, IsraelLuda Glozman Shtark, Department of Diagnostic Imaging, Rambam Health Care Campus, Haifa, IsraelKarin Arish, Department of Anesthesiology, Western Galilee Hospital, Nahariya, IsraelAhuva Engel, Department of Diagnostic Imaging, Rambam Health Care Campus, Haifa, Israel Journal Pediatric RadiologyOnline ISSN 1432-1998Prin...

Surgical breast biopsy not overused, study suggests

EurekAlert! - Medicine and Health — Wed, 01 Feb 2012 05:00:00 +0100

(American College of Radiology) Contrary to earlier findings, surgical breast biopsies may not be as overused as previously thought, according to a study in the February issue of the Journal of the American College of Radiology. Surgical breast biopsies are more invasive than needle biopsies, requiring an incision and the use of general anesthesia. (Source: EurekAlert! - Medicine and Health)

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Sciatic lateral popliteal block with clonidine alone or clonidine plus 0.2% ropivacaine : effect on the intra- and postoperative analgesia for lower extremity surgery in children: a randomized prospective controlled study

BMC Anesthesiology — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Clonidine appears promising more as an adjuvant in 0.2% ropivacaine and less than alone in the SLPB plus femoral block in children undergoing mild to moderate painful foot surgery, with no side effects.Trial registration: ClinicalTrials.gov, ISRCTN90832436, (ref: CCT-NAPN-20886). (Source: BMC Anesthesiology)

Elevated BIS and Entropy values after sugammadex or neostigmine: an electroencephalographic or electromyographic phenomenon?

Acta Anaesthesiologica Scandinavica — Wed, 01 Feb 2012 05:00:00 +0100

ConclusionThe EMG contamination of EEG causes BIS and Entropy values to rise during reversal of rocuronium‐induced NMB in light propofol‐remifentanil anesthesia. (Source: Acta Anaesthesiologica Scandinavica)

Comparison of malleable stylet and reusable and disposable bougies by?paramedics in a simulated difficult intubation

Anaesthesia — Wed, 01 Feb 2012 05:00:00 +0100

SummaryIn a randomised crossover study, 60 ambulance paramedics attempted tracheal intubation of a manikin model of a Cormack and Lehane grade 3/4 view using a Portex stylet, Portex and Frova single‐use bougies, and a Portex reusable bougie. Tracheal intubation within 30 s was achieved by 34/60 (57%) using the stylet, 18/60 (30%) using a Portex single‐use bougie, 16/60 (27%) using a Frova single‐use bougie and 5/60 (8%) using a Portex reusable bougie. The proportion intubating within 30 s was significantly higher with the stylet compared with any bougie (p < 0.001), but significantly lower with a Portex reusable bougie than any other device (p < 0.004). Participants rated the Portex reusable bougie as significantly more difficult to use than the other devices (p &...

Differential Effects of Cocaine on Dopamine Neuron Firing in Awake and Anesthetized Rats

Neuropsychopharmacology — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Stanislav Koulchitsky, Benjamin De Backer, Etienne Quertemont, Corinne Charlier & Vincent Seutin Keywords: dopamine; addiction & substance abuse; behavioral science; neurophysiology; electrophysiology; telemetry; cocaine (Source: Neuropsychopharmacology)

Magnetic Resonance Imaging Indicates Decreased Choroidal and Retinal Blood Flow in the DBA/2J Mouse Model of Glaucoma [Multidisciplinary Ophthalmic Imaging]

Investigative Ophthalmology — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions. The reduced ocular blood flow in DBA/2J mice compared with C57BL/6 control mice suggests that ischemia or hypoxia should be considered as a possible contributing factor in the optic neuropathy in the DBA/2J mouse model of glaucoma. (Source: Investigative Ophthalmology)

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Pediatric Analgesic Clinical Trial Designs, Measures, and Extrapolation: Report of an FDA Scientific Workshop

PEDIATRICS — Wed, 01 Feb 2012 05:00:00 +0100

Analgesic trials pose unique scientific, ethical, and practical challenges in pediatrics. Participants in a scientific workshop sponsored by the US Food and Drug Administration developed consensus on aspects of pediatric analgesic clinical trial design. The standard parallel-placebo analgesic trial design commonly used for adults has ethical and practical difficulties in pediatrics, due to the likelihood of subjects experiencing pain for extended periods of time. Immediate-rescue designs using opioid-sparing, rather than pain scores, as a primary outcome measure have been successfully used in pediatric analgesic efficacy trials. These designs maintain some of the scientific benefits of blinding, with some ethical and practical advantages over traditional designs. Preferred outcome measures...

Med Sci Monit 2012; 18(2):CR105-111 "The influence of heparin resistance on postoperative complications in patients undergoing coronary surgery"

Medical Science Monitor — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions: Mild forms of heparin resistance are relatively frequent and are not associated with increased morbidity and mortality. The isolation of severe heparin resistance as an independent predictor of death in our large cohort of coronary patients suggests that this phenomenon should be given more attention in future studies. (Source: Medical Science Monitor)

Cardiac Anaesthesia; Thoracic Anaesthesia

Anaesthesia — Wed, 01 Feb 2012 05:00:00 +0100

(Source: Anaesthesia)

A customized stylet for GlideScope® insertion of double lumen tubes.

Canadian Journal of Anaesthesia — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Bussières JS, Martel F, Somma J, Morin S, Gagné N PMID: 22302304 [PubMed - as supplied by publisher] (Source: Canadian Journal of Anaesthesia)

The Size 1 ProSeal™ laryngeal mask airway in infants: a randomized, noncrossover study with the Classic™ laryngeal mask airway.

Paediatric Anaesthesia — Wed, 01 Feb 2012 05:00:00 +0100

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Causes of death after hip fracture in senile patients.

Chinese Journal of Traumatology — Wed, 01 Feb 2012 05:00:00 +0100

This article reviews these causes from the aspects of patient's own factors, iatrogenic factors, medical treatment and other factors and provides some clues for further clinical application according to the recent foreign and domestic researches. According to the present research, it is essential for surgeons to perform a comprehensive estimation for patients suffering from hip trauma. PMID: 22300919 [PubMed - in process] (Source: Chinese Journal of Traumatology)

Closed Treatment of Overriding Distal Radial Fractures without Reduction in Children.

The Journal of Bone and Joint Surgery. American volume — Wed, 01 Feb 2012 05:00:00 +0100

CONCLUSIONS: This treatment protocol presents an alternative approach to overriding distal radial fractures in children and provides the orthopaedic surgeon a simple, effective, and cost and time-efficient method of treatment. LEVEL OF EVIDENCE: Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence. PMID: 22298057 [PubMed - in process] (Source: The Journal of Bone and Joint Surgery. American volume)

Bayesian enhanced meta‐analysis of post‐operative analgesic efficacy of additives for caudal analgesia in children

Acta Anaesthesiologica Scandinavica — Wed, 01 Feb 2012 05:00:00 +0100

ConclusionsNeostigmine provides the longest post‐operative analgesia. With clonidine, the duration of analgesia is shorter and sedation is increased, but the probability for PONV could be decreased. (Source: Acta Anaesthesiologica Scandinavica)