MedWorm: Craniofacial Surgery

Multicenter Study of Neurodevelopment in 3-Year-Old Children With and Without Single-Suture Craniosynostosis [Article]

Archives of Pediatrics — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions In this large, carefully controlled, multicenter study, we observed consistently lower mean neurodevelopmental scores in children with single-suture craniosynostosis compared with controls. These results provide further support for neurodevelopmental screening in young children with single-suture craniosynostosis. (Source: Archives of Pediatrics)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Factors influencing blood loss and allogeneic blood transfusion practice in craniosynostosis surgery.

Paediatric Anaesthesia — Sun, 05 Feb 2012 17:50:07 +0100

Authors: Stricker PA, Fiadjoe JE, Jobes DR PMID: 22272672 [PubMed - in process] (Source: Paediatric Anaesthesia)

The original family revisited after 37 years: odontoma–dysphagia syndrome is most likely caused by a microduplication of chromosome 11q13.3, including the FGF3 and FGF4 genes

Clinical Oral Investigations — Thu, 02 Feb 2012 06:56:37 +0100

Conclusion The microduplication identified in this family represents the most likely cause of the odontoma–dysphagia syndrome and implies that the syndrome is caused by a gain of function of the FGF3 and FGF4 genes. Clinical relevance Mutations of FGF receptor genes can cause craniofacial syndromes such as odontoma–dysphagia syndrome. Following this train of thought, an evaluation of FGF gene family in sporadic odontoma could be worthwhile. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00784-012-0676-6Authors Thomas Ziebart, Department of Oral and Maxillofacial Surgery, University Medical Center of the Johannes Gutenberg-University of Mainz, Augustusplatz 2, 55131 Mainz, GermanyFlorian G. Draenert, Department of O...

mTOR Inhibitors and its Role in the Treatment of Head and Neck Squamous Cell Carcinoma

Current Treatment Options in Oncology — Thu, 26 Jan 2012 16:44:15 +0100

Opinion statement Head and neck squamous cell carcinomas (HNSCC) represent 6% of all cancers diagnosed each year in the United States, affecting approximately 43,000 new patients and resulting in approximately 12,000 deaths. Currently, three main rapalogs exist for the treatment of cancer: CCI-779 (temsirolimus), RAD001 (everolimus), and AP235373 (deforolimus). Clinicians managing HNSCC need to be aware of the three rapalogs. Extensive evidence has shown rapamycin-analogs to be effective agents in the treatment of a number of solid tumors. While extensive preclinical data suggests that HNSCC would be an appropriate tumor type to benefit from inhibition of the mTOR pathway, limited clinical data is yet available to support this. Numerous phase II trials evaluating mTOR inhi...

Factors influencing blood loss and allogeneic blood transfusion practice in craniosynostosis surgery

Pediatric Anesthesia — Thu, 26 Jan 2012 12:13:06 +0100

(Source: Pediatric Anesthesia)

Intraoperative and postoperative hyponatremia with craniosynostosis surgery

Pediatric Anesthesia — Mon, 23 Jan 2012 12:11:49 +0100

Conclusions: Clinically significant intraoperative hyponatremia was not a feature of major craniofacial surgery in our institution. Mild postoperative hyponatremia was relatively common on POD1. (Source: Pediatric Anesthesia)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Maxillofacial Reconstruction Using Polyetheretherketone Patient-Specific Implants by “Mirroring” Computational Planning

Aesthetic Plastic Surgery — Thu, 19 Jan 2012 06:45:01 +0100

Abstract In the vast majority of cases, precise symmetric reconstruction of maxillofacial defects remains an unsolved problem for craniofacial surgeons. Computer-designed alloplastic implants have contributed considerably to improvement in the accuracy and reliability of facial rehabilitation, rapidly becoming an irreplaceable part of the surgical armamentarium. In recent years, the subsequently developed new generation of computational technologies has allowed planning to be done by preoperative “mirroring” using the healthy side as a template to fabricate an ideal prosthesis for reestablishment of facial symmetry. Two cases of facial defects are reported, one of the midface and another of the lower face reconstructed using a computer-designed polyetheretherketone (PE...

Myringoplasty in children with cleft palate and craniofacial anomaly

International Journal of Pediatric Otorhinolaryngology — Tue, 17 Jan 2012 21:16:10 +0100

Abstract: Objectives: Analyze the anatomical and audiological success rates of myringoplasty in children with craniofacial anomaly, cleft palate and compare them to a control group.Methods: Retrospective review of medical records for all children who underwent myringoplasty between 1997 and 2007. The following data was recorded: sex, age, perforation side, size, location and etiology, surgical approach, type of myringoplasty, graft material, season of surgery, preoperative status of the operated and contralateral ear, history of previous otologic surgery, and adenoidectomy or tonsillectomy.Results: Myringoplasty outcomes of 22 craniofacial anomaly patients (15/22 were cleft palate patients) were compared to 144 controls. Children in the craniofacial anomaly group demonstrated a tendency to...

Retrospective Review of Resorbable Plate Fixation in Pediatric Craniofacial Surgery: Long-term Outcome [Archives Classic: A Contemporary Perspective]

Archives of Facial Plastic Surgery — Mon, 16 Jan 2012 05:00:00 +0100

(Source: Archives of Facial Plastic Surgery)

Neurodevelopmental functioning of infants with untreated single-suture craniosynostosis during early infancy

Child's Nervous System — Fri, 13 Jan 2012 17:18:39 +0100

Conclusions Untreated SSC is associated with an increased incidence of developmental delay during early infancy, with motor skills appearing the most vulnerable to impairment during this developmental phase. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00381-011-1660-1Authors Annette C. Da Costa, Department of Plastic and Maxillofacial Surgery, The Royal Children’s Hospital, Melbourne, VIC 3052, AustraliaVicki A. Anderson, Murdoch Childrens Research Institute, Melbourne, VIC, AustraliaRavi Savarirayan, Murdoch Childrens Research Institute, Melbourne, VIC, AustraliaJacquie A. Wrennall, Department of Psychology, The Royal Children’s Hospital, Melbourne, VIC, AustraliaDavid K. Chong, Department of Plastic and Maxillofacial Surgery, The Ro...

Local Strategies to Address Health Needs of Individuals with Orofacial Clefts in Alagoas, Brazil.

The Cleft Palate-Craniofacial Journal — Wed, 11 Jan 2012 05:00:00 +0100

Conclusions: Findings revealed high levels of unmet medical needs and provided an evidence base for health care planning. Collaborative action was crucial and might be applied to other regions in Brazil. Key-words: Cleft lip; cleft palate; health care. PMID: 22236341 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

MedWorm Sponsor Message: Find the best January Sales in the UK.

The Cleft-Columellar Angle: A Useful Variable to Describe the Unilateral Cleft Lip-Associated Nasal Deformity.

The Cleft Palate-Craniofacial Journal — Wed, 11 Jan 2012 05:00:00 +0100

Conclusions: Measurement of the cleft-columellar angle in two-dimensional digital photography is simple and correlative, capturing a substantial portion of non-expert severity ratings of the constellation of deformities seen with the unilateral cleft lip deformity. Given its ease of application, the cleft-columellar angle is a useful variable in the description of the unilateral cleft lip deformity and may find utility across institutions as cleft surgeons seek to advance surgical care through outcomes research. Key Words: Cleft lip, cleft nasal deformity, objective measures. PMID: 22236271 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

Stereophotogrammetric analysis of naso-labial morphology among Asian Malays: influence of age and sex.

The Cleft Palate-Craniofacial Journal — Wed, 11 Jan 2012 05:00:00 +0100

Conclusion: This study has provided a new 3D database for nose and lip morphology in Malays and demonstrated patterns of variation that can be used by surgeons to make comparisons within and between different human populations and also to develop treatment plans for their patients. Keywords: Asian Malay, labial, nasal, stereophotogrammetry. PMID: 22236217 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

Health-related problems and quality of life in patients with syndromic and complex craniosynostosis

Child's Nervous System — Tue, 10 Jan 2012 17:00:53 +0100

Conclusions The overall quality of life is lower in patients with syndromic and complex craniosynostosis. To improve quality of life, more attention is needed for problems with vision and speech. Content Type Journal ArticleCategory Original PaperPages 1-4DOI 10.1007/s00381-012-1681-4Authors Tim de Jong, Department of Plastic and Reconstructive Surgery and Hand Surgery, Dutch Craniofacial Center, Erasmus MC, Sophia Children’s Hospital, Room Ee 15.91, Dr. Molewaterplein 50, 3015 GE Rotterdam, The NetherlandsMarianne Maliepaard, Department of Plastic and Reconstructive Surgery and Hand Surgery, Dutch Craniofacial Center, Erasmus MC, Sophia Children’s Hospital, Room Ee 15.91, Dr. Molewaterplein 50, 3015 GE Rotterdam, The NetherlandsNatalja Bannink, Department of Pla...

Factors affecting the outcome of patients undergoing corrective surgery for craniosynostosis: A retrospective analysis of 95 cases

Neurology India — Mon, 02 Jan 2012 05:00:00 +0100

Conclusion: The outcome of patients undergoing craniosynostosis in terms of ICU and hospital stay is affected by the number of medical and postoperative conditions, type of anesthesia induction, duration of surgery and type of recovery. (Source: Neurology India)

Mesenchymal chondrosarcoma: clinicopathologic study of 20 cases.

Archives of Pathology and Laboratory Medicine — Sun, 01 Jan 2012 05:00:00 +0100

Conclusions.-Mesenchymal chondrosarcoma presents multiple challenges. Diagnostic pitfalls include inadequate biopsy samples, which may result in sample error. Sox9 has been proposed as a unique marker for mesenchymal chondrosarcoma which may improve diagnostic specificity. Treatment and prognosis vary considerably. Patients who receive surgery and chemotherapy seem to fare better. Multicenter studies with higher sample numbers may improve our understanding of this malignancy. PMID: 22208489 [PubMed - in process] (Source: Archives of Pathology and Laboratory Medicine)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Indication process of cochlear implant for a child with cerebral palsy: a case report

Revista da Sociedade Brasileira de Fonoaudiologia — Sat, 17 Dec 2011 22:11:29 +0100

This study highlights the importance of the pre-surgical protocol for children with CP who are candidates for CI. Through assessment tools directed to the global aspects of development, one can obtain specific information that improve parent counseling regarding the child's prognosis and make it possible to trace actual hearing rehabilitation goals. (Source: Revista da Sociedade Brasileira de Fonoaudiologia)

Attitudes of pregnant women and mothers of children with orofacial clefts toward prenatal diagnosis of nonsyndromic orofacial clefts in a semiurban set-up in India

Indian Journal of Plastic Surgery — Thu, 15 Dec 2011 05:00:00 +0100

Conclusions: Majority of the respondents from both the groups chose to continue with the pregnancy affected with a cleft when questioned regarding hypothetical prenatal ultrasound diagnosis of the cleft. (Source: Indian Journal of Plastic Surgery)

Awareness among medical fraternity regarding the role of plastic surgeon

Indian Journal of Plastic Surgery — Thu, 15 Dec 2011 05:00:00 +0100

Vijay Kumar, Arun Kumar Singh, Ameer Faisal, R NandiniIndian Journal of Plastic Surgery 2011 44(3):494-497The field of plastic surgery, while being famous for aesthetic surgery, also includes craniofacial surgery, hand surgery, burn surgery, microsurgery, reconstructive plastic surgery and paediatric plastic surgery. The magnanimous progress in these areas, though a hot topic in conferences, remains cryptic to the layman and also to generalists who are and will remain to be the most important referral source of these patients. [1] Hence, it becomes the duty of plastic surgeons themselves to spread awareness regarding their chosen field of endeavour. (Source: Indian Journal of Plastic Surgery)

Interdental distraction osteogenesis for the management of alveolar clefts: archwise distraction

International Journal of Oral and Maxillofacial Surgery — Tue, 06 Dec 2011 05:00:00 +0100

Abstract: Bone grafting is a successful protocol for cleft repair but it is very challenging to close large gaps using local gingival tissue. In the last decade, interdental distraction osteogenesis has been introduced as a successful treatment protocol for repairing such large clefts. In this article a new method for closing the alveolar cleft is introduced and one case is presented. A tooth supported distractor which was specially designed to be inserted on to the main arch wire was used for the distraction. The aim was to distract the tooth segments through the curve of the dental arch and achieve complete closure of the gaps. The distractor introduced had several advantages: it is simple to apply, activate and remove; there is no need for a second operation; it is an outpatient procedu...

Efficacy of Minimally Invasive Sagittal Craniosynostosis Repair

AAP Grand Rounds — Thu, 01 Dec 2011 05:00:00 +0100

(Source: AAP Grand Rounds)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Prevention and Management of Positional Skull Deformities in Infants

PEDIATRICS — Thu, 01 Dec 2011 05:00:00 +0100

This report provides guidance for the prevention, diagnosis, and management of positional skull deformity in an otherwise normal infant without evidence of associated anomalies, syndromes, or spinal disease. (Source: PEDIATRICS)

Endoscopic management of anterior cranial fossa meningiomas

Operative Techniques in Otolaryngology - Head and Neck Surgery — Thu, 01 Dec 2011 05:00:00 +0100

Meningiomas of the anterior skull base have been traditionally approached through transcranial or combined craniofacial routes. While these approaches offer wide exposure and working space, brain retraction, neurovascular manipulation, sinus obliteration, wound healing, and cosmesis can be significant issues. With the evolution of endoscope-assisted surgery, transnasal endoscopic approaches have developed as useful alternatives. These approaches can provide visualization comparable to or better than microscope-assisted surgery, as the endoscope provides excellent resolution of anatomic and pathologic details down these narrow corridors. Moreover, the use of angled endoscopes and instruments enables the surgeon to visualize and remove structures around the corners and avoid brain retraction...

Endoscopic management of juvenile nasopharyngeal angiofibromas

Operative Techniques in Otolaryngology - Head and Neck Surgery — Thu, 01 Dec 2011 05:00:00 +0100

The origin of juvenile angiofibroma is usually around the region of the sphenopalatine artery, and the surgical management of large tumors can be challenging. Traditional approaches to advanced tumors involved open transfacial or transcranial microscope-assisted surgery. Advances in image guidance and endonasal endoscopic techniques have made endonasal endoscopic approaches to the pterygopalatine and infratemporal possible. Endoscopes allow for greater magnification and visualization of complex anatomy, and endoscopic approaches allow the surgeon to avoid manipulation of the osseous midfacial structures that may result in craniofacial abnormalities in this adolescent population. (Source: Operative Techniques in Otolaryngology - Head and Neck Surgery)

Combined endoscopic and open approach to resection of the anterior skull base

Operative Techniques in Otolaryngology - Head and Neck Surgery — Thu, 01 Dec 2011 05:00:00 +0100

Although en-bloc resection is the traditional teaching in oncological surgery, with recent technologic advancements and literature to support both safety and efficacy, there has been a growing acceptance of alternative techniques for the surgical management of paranasal sinus and anterior skull base malignancies. The endoscopic-assisted external approach affords many of the benefits of endoscopic resection while allowing for the management of lesions with marked intracranial extension that would otherwise require anterior craniofacial resection. Here we describe our endoscopic technique for resection of the anterior skull base and its role when combined with anterior craniotomy. (Source: Operative Techniques in Otolaryngology - Head and Neck Surgery)

Colon atresia and frontal encephalocele: a rare association

Journal of Pediatric Surgery — Thu, 01 Dec 2011 05:00:00 +0100

We present a case of an infant with colonic atresia and a frontal encephalocele and believe this to be a newly reported association. We review possible pathogenic mechanisms. (Source: Journal of Pediatric Surgery)

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Prospective assessment of complications associated with ultrasound activated resorbable pin osteosynthesis in pediatric craniofacial surgery: preliminary results.

Neurocirugia — Thu, 01 Dec 2011 05:00:00 +0100

Authors: Nkenke E, Vairaktaris E, Schwarz S, Eyüpoglu I, Ganslandt O, Leis T, Knipfer C, Stelzle F Abstract Ultrasound activated resorbable pin osteosynthesis (UARPO) has recently shown favourable results in operations on children suffering for craniosynostosis. However, data on complications coming with this new technique in children suffering from craniosynostoses are scarce and have only been assessed retrospectively so far. It has been the aim of the present study to prospectively follow up children undergoing craniosynostosis surgery with a focus on complications related to UARPO materials. Ten pediatric patients (3 female/7 male) were operated due to craniosynostosis at an average age of 9.1±3.8 months using UARPO (SonicWeld/Resorb-X, KLS Martin, Tuttlingen, Germany). Clini...

Craniofacial development and physiological state after early oral breathing in rats

European Journal of Oral Sciences — Thu, 01 Dec 2011 05:00:00 +0100

In this study we determined whether craniofacial development in rats could be influenced by an early temporary (3 d) nasal obstruction associated with forced oral breathing. The rats were killed at specific time points after surgery. Plasma samples were taken for biochemical analyses, and cephalometric measurements were performed. Shortly after nasal obstruction, the vertical nasomaxillary complex and the longitudinal skull base proved to be smaller in both sexes of test rats compared with controls. This was maintained in male rats but not in female rats. In female rats, only the longitudinal skull base remained somewhat shorter as the animals grew older. Reversible nasal obstruction was further associated with reduced dimensions of the olfactory bulbs lasting into adulthood and an initi...

Progressive craniofacial bone loss after cosmetic surgery at the forehead

Skeletal Radiology — Wed, 30 Nov 2011 09:21:16 +0100

We present the case of a 59-year-old woman with a history of plastic surgery at the forehead who complained of progressive indentations at the frontal skull. CT and MR scans revealed significant bone thinning, presenting as lytic skull lesions, which progressed over a period of 3 years. Biopsies were obtained from the lytic lesions and histology showed fibrotic tissue, synthetic residue of previous cosmetic procedure, and no evidence of infection or neoplasm. Progressive cranial bone resorption places the patient at increased risk for cerebral injury. This case highlights a potential complication after cosmetic facial surgery, with bony resorption resulting in both skull deformation and increased risk for cerebral injury. Content Type Journal ArticleCategory Case ReportPages...

Early Dimensional Changes in Maxillary Cleft Size and Arch Dimensions of Children with Cleft Lip and Palate and Cleft Palate.

The Cleft Palate-Craniofacial Journal — Tue, 29 Nov 2011 05:00:00 +0100

Conclusions: Cleft widths decreased after lip closure and/or soft palate closure. The UCLP children had wider maxillary arch dimensions than the CP and PRS children during the first years of life, but after hard palate closure the transverse growth was reduced in the UCLP children. At 5 years the UCLP children had smaller maxillary widths than the CP and PRS children especially at the level of the cuspids. Key words: cleft lip and palate, cleft palate, cleft size, maxillary arch dimensions and two-stage palatal repair. PMID: 22122198 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

Neuroimaging in cluster headache and other trigeminal autonomic cephalalgias

The Journal of Headache and Pain — Thu, 24 Nov 2011 17:51:49 +0100

Abstract The central nervous system mechanisms involved in trigeminal autonomic cephalalgias, a group of primary headaches characterized by strictly unilateral head pain that occurs in association with ipsilateral craniofacial autonomic features, are still not comprehensively understood. However, functional imaging methods have revolutionized our understanding of mechanisms involved in these primary headache syndromes. The present review provides a brief overview of the major modern functional neuroimaging techniques used to examine brain structure, biochemistry, metabolic state, and functional capacity. The available functional neuroimaging data in cluster headache and other TACs will thus be summarized. Although the precise brain structures responsible for these primary ...

MedWorm Sponsor Message: Find the best January Sales in the UK.

Craniosynostosis and 3-Dimensional Computed Tomography

Seminars in Ultrasound CT and MRI — Tue, 22 Nov 2011 20:40:15 +0100

Craniosynostosis is when cranial sutures fuse prematurely. It causes cosmetic deformity and may limit brain growth with more serious consequences, such as hydrocephalus. It may involve one or more sutures, may be syndromic, and is thought most likely to result from genetic causes. Specific sutural closures result in reproducible cranial appearances and head shapes. Three-dimensional computed tomography has become the standard for preoperative diagnosis to allow surgical planning as well as postsurgical assessment. Early diagnosis allows early surgical management, which improves outcome. Nonsyndromic and syndromic craniosynostoses are illustrated in this pictorial review. (Source: Seminars in Ultrasound CT and MRI)

Microtia: Epidemiology and genetics

American Journal of Medical Genetics Part A — Mon, 21 Nov 2011 05:00:00 +0100

AbstractMicrotia is a congenital anomaly of the ear that ranges in severity from mild structural abnormalities to complete absence of the ear, and can occur as an isolated birth defect or as part of a spectrum of anomalies or a syndrome. Microtia is often associated with hearing loss and patients typically require treatment for hearing impairment and surgical ear reconstruction. The reported prevalence varies among regions, from 0.83 to 17.4 per 10,000 births, and the prevalence is considered to be higher in Hispanics, Asians, Native Americans, and Andeans. The etiology of microtia and the cause of this wide variability in prevalence are poorly understood. Strong evidence supports the role of environmental and genetic causes for microtia. Although some studies have identified candidate gen...

Exploratory study on the effect of osteoactivin on bone formation in the rat critical‐size calvarial defect model

Journal of Periodontal Research — Sun, 20 Nov 2011 05:00:00 +0100

Conclusion: Osteoactivin demonstrates a significant potential to support bone regeneration/formation. Studies using discriminating large animal models are necessary to explore clinical application for periodontal and craniofacial indications. (Source: Journal of Periodontal Research)

A variant of the Ekman-Westborg and Julin trait

International Journal of Oral and Maxillofacial Surgery — Fri, 18 Nov 2011 05:00:00 +0100

Abstract: Ekman-Westborg and Julin is a trait that shows multiple macrodontia and multituberculism affecting only the teeth with no other anomalies (E-WJ). The aim of this report is to present a case which appears to manifest all the clinical signs of the E-WJ trait including odontoma formation. A 18-year-old girl with gingival inflammation particularly in the maxillary insicor area was referred to the authors’ department. Panoramic, periapical and cephalometric radiographs were examined and complex odontoma associated with unerupted maxillary permanent lateral incisors was revealed. Intraoral examination revealed anterior crossbite, Angle Class III type malocclusion with mandibulary prominence and macrodontia of teeth 37, 12, 11 and 21. The patient was accepted as a new sporadic case of...

Fronto-facial monobloc distraction in syndromic craniosynostosis. Three-dimensional evaluation of treatment outcome and facial growth

International Journal of Oral and Maxillofacial Surgery — Thu, 17 Nov 2011 05:00:00 +0100

The objectives of this study were to investigate the treatment effect and stability of fronto-facial monobloc distraction osteogenesis. Five consecutive patients who underwent monobloc distraction were included (aged 4.8–18.4 years). Three patients had Crouzon syndrome, one had Apert syndrome, and one had Pfeiffer syndrome. The evaluation included clinical records, serial cephalograms for at least 1-year follow up (average 24.6 months). The treatment and post-treatment changes were measured. The intracranial volume, upper airway volume and globe protrusion were calculated from CT before and after treatment. After distraction, the supraorbital region was advanced 15.3mm forward, the midface demonstrated forward advancement of 17.7mm, 22.1mm and 23.1mm at orbitale, anterior nasal spine and...

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Generation of normative pediatric skull models for use in cranial vault remodeling procedures

Child's Nervous System — Wed, 16 Nov 2011 17:59:19 +0100

Conclusions Normative head shapes for pediatric patients have wide application for craniofacial surgery including planning, practice, standarized operative repair, and standardized measurement and reporting of outcomes. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00381-011-1630-7Authors Nikoo R. Saber, Centre for Image Guided Innovation & Therapeutic Intervention (CIGITI), The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8John Phillips, Division of Plastic Surgery—Craniofacial Program, The Hospital for Sick Children, Toronto, CanadaThomas Looi, Centre for Image Guided Innovation & Therapeutic Intervention (CIGITI), The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X...

Deficient language acquisition in children with single suture craniosynostosis and deformational posterior plagiocephaly

Child's Nervous System — Mon, 14 Nov 2011 16:55:36 +0100

Conclusions We found a noticeable developmental risk for specific language impairment in children with nonsyndromic SSC, and that the deviant language development is observable already in early infancy. Contrary to previous beliefs, the developmental risk for defective language development in deformational posterior plagiocephaly was found in both operated and non-operated subjects. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00381-011-1623-6Authors Pirjo Korpilahti, Department of Behavioural Sciences and Philosophy, University of Turku, Turku, FinlandPia Saarinen, Cleft Palate and Craniofacial Centre, Department of Plastic Surgery, Helsinki University Hospital, Helsinki, FinlandJyri Hukki, Cleft Palate and Craniofacial Centre, Departmen...

Are There Challenges in the Interpretation of Head and Neck Specimens?

Surgical Pathology Clinics — Sun, 13 Nov 2011 17:11:53 +0100

The spectrum of possible diagnoses posed by the mingling of diverse tissue types present in the region of the head and neck can be challenging for all involved in the daily practice of surgical pathology. The purpose of this issue is not to cover every aspect of head and neck pathology but rather to have well recognized experts provide a foundation for diagnosis of critical entities in this region. Articles in this issue focus on aspects of interpretation that can be especially vexing in the head and neck, including salivary gland lesions, craniofacial bone lesions, odontogenic lesions, lichenoid lesions of oral mucosa, sinonasal tract, oral cavity and oropharynx, and larynx and hypopharynx. The articles are designed to offer a practical reference for the everyday interpretation of biopsie...

Bone Lesions of the Head and Neck

Surgical Pathology Clinics — Sun, 13 Nov 2011 17:11:53 +0100

This article describes the clinical, radiographic, and pathologic features of tumors and tumorlike lesions affecting the bones of the head and neck region. Emphasis is placed on common bone lesions affecting the craniofacial skeleton, particularly those that occur with more frequency or those that are unique to this part of the skeleton. Several of these lesions pose a diagnostic challenge to the pathologist. To ensure that a correct diagnosis is rendered, it is of utmost importance that accurate and detailed clinical and radiographic information is available. (Source: Surgical Pathology Clinics)

Improvement in survival during the past 4 decades among patients with anterior skull base cancer

Head and Neck — Sun, 13 Nov 2011 08:18:18 +0100

ConclusionsThe survival of patients with anterior skull base cancer is improving. Surgery after 1996 is an independent prognostic factor for an improved outcome. © 2011 Wiley Periodicals, Inc. Head Neck, 2011 (Source: Head and Neck)

MedWorm Sponsor Message: Find the best January Sales in the UK.

Craniofacial reconstruction as a treatment for elevated intracranial pressure

Child's Nervous System — Tue, 08 Nov 2011 16:48:43 +0100

Conclusions Using modern diagnostic and surgical techniques, including invasive ICP monitoring, increased intracranial pressure can be successfully managed by an experienced, multidisciplinary, craniofacial team. Our treatment paradigm and operative management scheme is discussed. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00381-011-1615-6Authors Lissa C. Baird, Division of Neurosurgery, University of California at San Diego, San Diego, CA, USADavid Gonda, Division of Neurosurgery, University of California at San Diego, San Diego, CA, USASteven R. Cohen, Division of Craniofacial and Plastic Surgery, Rady Children’s Hospital, San Diego, CA, USALars H. Evers, Division of Craniofacial and Plastic Surgery, Rady Children’s Hospital, San ...

Obituary: Bernard Sarnat, 99, UCLA professor, pioneer in field of craniofacial biology

UCLA Newsroom: Health Sciences — Thu, 03 Nov 2011 23:00:00 +0100

Dr. Bernard G. Sarnat, D.D.S., an eminent plastic surgeon and research scientist who made pioneering contributions to the understanding of craniofacial development and the causes of facial deformities, died Oct. 21 in Los Angeles of respiratory failure. He was 99. Sarnat joined the UCLA School of Dentistry in 1969 as an adjunct professor of oral biology and in 1974 received a joint appointment in the UCLA School of Medicine's division of plastic surgery. He also operated a private practice as a plastic surgeon in Beverly Hills and was associated with Cedars–Sinai Medical Center for more than 20 years, first as chief of plastic surgery and later as a senior research scientist. Sarnat's groundbreaking studies of how biology influences medical and dental treatment led to m...

Does postoperative ‘M’ technique® massage with or without mandarin oil reduce infants’ distress after major craniofacial surgery?

Journal of Advanced Nursing — Thu, 03 Nov 2011 04:00:00 +0100

Conclusions. Results do not support a benefit of ‘M’ technique® massage with or without mandarin oil in these young postoperative patients. Several reasons may account for this: massage given too soon after general anaesthesia, young patients’ fear of strangers touching them, patients not used to massage. (Source: Journal of Advanced Nursing)

The Trans-Sutural Distraction Osteogenesis for 22 Cases of Craniosynostosis: A New, Easy, Safe, and Efficient Method in Craniosynostosis Surgery

Pediatric Neurosurgery — Wed, 02 Nov 2011 23:00:00 +0100

Pediatr Neurosurg 330708 (DOI:10.1159/000330708) (Source: Pediatric Neurosurgery)

Facial aesthetics and perceived need for further treatment among adults with repaired cleft as assessed by cleft team professionals and laypersons.

European Journal of Orthodontics — Wed, 02 Nov 2011 04:00:00 +0100

The objectives of this study were to compare the ratings of professionals and laypeople with and without a cleft regarding the facial aesthetics of adult patients previously treated for orofacial clefting. The necessity for further treatment, as perceived by the respective groups, is also compared. The design of the study was a cross-sectional study. Professionals (two plastic surgeons, one dentist, one orthodontist, and one psychologist) and laypeople (one male and one female adult without a cleft and one male and one female adult with a cleft) were recruited to rate photographs of 80 non-syndromic cleft patients treated by the Australian Craniofacial Unit from 1975 to 2009. Facial aesthetics were measured by a visual analogue scale (VAS; 0-100 mm). High values indicated good aesthetics. ...

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

A Unique Case of Tessier 30 and Bilateral Cleft Lip and Palate: A New Clinical Syndrome?

The Cleft Palate-Craniofacial Journal — Sun, 30 Oct 2011 04:00:00 +0100

Conclusion: We present a unique case of a child with a Tessier 30 cleft associated with bilateral cleft lip and palate, in the absence of intraoral masses or limb anomalies. Previous reports of median facial clefts have occurred either in the presence of intraoral hamartomas suggesting the palatal defects are a result of sequence abnormalities, or in association with extremity findings consistent with the spectrum of orofaciodigital syndrome. The case we present is distinct and may represent a new clinical syndrome. Keywords: Tessier 30; Bilateral cleft lip; Bilateral cleft palate; Bilateral cleft lip and palate; Mandible/mandibular cleft; Bifid tongue; Craniofacial cleft. PMID: 22034959 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

Early endoscopy-assisted treatment of multiple-suture craniosynostosis

Child's Nervous System — Sat, 29 Oct 2011 05:41:56 +0100

Conclusion Endoscopy-assisted surgery for correction of craniosynostosis in children under 4 months represents a valid and safe management option. Early treatment may contribute to prevent the development of associated ventriculomegaly and Chiari I malformation. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00381-011-1621-8Authors Mónica Rivero-Garvía, Unit of Pediatric Neurosurgery, Department of Neurosurgery, Virgen del Rocío University Hospital, Avda. Manuel Siruot s/n, 41013 Seville, SpainJavier Marquez-Rivas, Unit of Pediatric Neurosurgery, Department of Neurosurgery, Virgen del Rocío University Hospital, Avda. Manuel Siruot s/n, 41013 Seville, SpainAna Belén Rueda-Torres, Unit of Pediatric Neurosurgery, Department of Neurosu...

Clinical relevance of blast-related traumatic brain injury

Acta Neurochirurgica — Fri, 28 Oct 2011 16:44:21 +0100

Content Type Journal ArticleCategory EditorialPages 1-4DOI 10.1007/s00701-011-1210-3Authors Geoffrey Appelboom, Department of Neurological Surgery, The Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USAJames Han, Department of Neurological Surgery, The Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USASam Bruce, Department of Neurological Surgery, The Neurological Institute, Columbia University College of Physicians and Surgeons, New York, NY 10032, USACaroline Szpalski, Department of Plastic and Craniofacial Surgery, New York University (NYU), New York, NY 10016, USAE. Sander Connolly, Department of Neurological Surgery, The Neurological Institute, Columbia University College of P...

Serial Head Circumference and Neurodevelopmental Screening after Surgical Correction for Single- and Multiple-Suture Craniosynostosis.

The Cleft Palate-Craniofacial Journal — Fri, 28 Oct 2011 04:00:00 +0100

Conclusions: Patients chosen for revision surgery display not only a larger decline in head circumference, but also more neurodevelopmental findings prior to revision. Furthermore, surgical revision has a significant association with both improved neurodevelopmental screening and head circumference. Key Words: Craniosynostosis, Neurodevelopment, Head Circumference. PMID: 22034904 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

Fully 3‐dimensional digitally planned reconstruction of a mandible with a free vascularized fibula and immediate placement of an implant‐supported prosthetic construction

Head and Neck — Mon, 24 Oct 2011 04:00:00 +0100

ConclusionIt was possible to plan a mandibular reconstruction with immediate prosthetic loading completely by 3D virtual techniques. Head Neck, 2011 (Source: Head and Neck)

MedWorm Sponsor Message: Find the best January Sales in the UK.

A comparison of results using nasoalveolar moulding in cleft infants treated within 1 month of life versus those treated after this period: development of a new protocol

International Journal of Oral and Maxillofacial Surgery — Mon, 24 Oct 2011 04:00:00 +0100

This study concluded that the effects of NAM were most significant in group I. Group II patients also benefited from NAM, although to a lesser extent. This study validates the use of NAM in infants presenting late for treatment. (Source: International Journal of Oral and Maxillofacial Surgery)

Brain and ventricular volume in patients with syndromic and complex craniosynostosis

Child's Nervous System — Wed, 19 Oct 2011 15:45:08 +0100

Conclusions Patients with syndromic craniosynostosis have a normal total brain volume compared to normal controls. Increased ventricular volume is associated with Apert syndrome and Chiari I malformations, which is most commonly found in Crouzon syndrome. We advice screening of all patients with Apert and Crouzon syndrome for the development of enlarged ventricle volume and the presence of a Chiari I malformation. Content Type Journal ArticleCategory Original PaperPages 1-4DOI 10.1007/s00381-011-1614-7Authors T. de Jong, Department of Plastic and Reconstructive Surgery, and Hand Surgery, Sophia Children’s Hospital, Erasmus University Medical Center, Rotterdam, The NetherlandsB. F. M. Rijken, Department of Plastic and Reconstructive Surgery, and Hand Surgery, Soph...

Masseter muscle termination over the deep surface of the temporal fascia: look out the wrong path

Surgical and Radiologic Anatomy — Wed, 19 Oct 2011 15:44:40 +0100

Conclusion Fibres belonging to masseter muscle pass up to the zygomatic arch and terminate on the deep surface of the temporal fascia. Awareness of the nature and trajectory of these muscular fibres allows us to avoid taking “wrong path” when approaching the temporal muscle tendon on the coronoid process via the temporal fossa. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00276-011-0882-yAuthors Pierre Guerreschi, Plastic Surgery Department, Lille Regional University Hospital, 2 avenue Oscar Lambret, 59037 Lille Cedex, FranceThomas Gahagnon, Plastic Surgery Department, Lille Regional University Hospital, 2 avenue Oscar Lambret, 59037 Lille Cedex, FranceChristian Vacher, Maxillofacial Surgery Department, Beaujon Hospital, AP-HP, 100,...

Bioresorbable distraction device for the treatment of airway problems for infants with Robin sequence

Clinical Oral Investigations — Tue, 18 Oct 2011 15:58:54 +0100

Abstract Pierre Robin sequence is a well known craniofacial entity. There are numerous ways to treat the respiratory insufficiency, but sometimes surgical intervention is needed. Tracheotomy could be associated with morbidity, and distraction osteogenesis has been established as a stable method to obtain a safe airway. Distraction osteogenesis has traditionally been performed with an external device. In this manuscript we describe the feasibility of an internal bioresorbable device. Retrospective descriptive study was performed in a tertiary academic children’s hospital. After multidisciplinary team consultation, 12 consecutive patients with Robin sequence were treated with this internal distraction device. The mean age at surgery was 32 days, and the average amount...

Image Fusion in Preoperative Planning

Facial Plastic Surgery Clinics of North America — Tue, 18 Oct 2011 02:59:50 +0100

This article presents a comprehensive overview of generating a digital Patient-Specific Anatomic Reconstruction (PSAR) model of the craniofacial complex as the foundation for a more objective surgical planning platform. The technique explores fusing the patient's 3D radiograph with the corresponding high-precision 3D surface image within a biomechanical context. As taking 3D radiographs has been common practice for many years, this article describes various approaches to 3D surface imaging and the importance of achieving high-precision anatomical results to simulate surgical outcomes that can be measured and quantified. With the PSAR model readily available for facial assessment and virtual surgery, the advantages of this surgical planning technique are discussed. (Source: Facial Plastic S...

MedWorm Sponsor Message: Please support the Doctors In Chains campaign for the medics tortured and sentenced for up to 15 years in Bahrain. #FreeDoctors

Creation of the Virtual Patient for the Study of Facial Morphology

Facial Plastic Surgery Clinics of North America — Tue, 18 Oct 2011 02:59:50 +0100

This article describes how a virtual patient is created and manipulated and the practical use of this technology. It takes the quantification of the 3D surface further by proposing a reference framework of landmarks of craniofacial structure that can be used for comparison of surgical change, growth, gender, and phenotype. (Source: Facial Plastic Surgery Clinics of North America)

Craniostenosis

Journal of Pediatric Neurosciences — Mon, 10 Oct 2011 04:00:00 +0100

Chidambaram Balasubramaniam, Santosh M RaoJournal of Pediatric Neurosciences 2011 6(3):23-26Craniostenosis is a common problem in the pediatric neurosurgery departments. The management of this problem is still evolving. Some misconceptions exist regarding this condition particularly regarding the indications for surgery. The author started performing this surgery nearly two decades ago. The experience gained over time as well as the problems encountered are discussed. (Source: Journal of Pediatric Neurosciences)

Presurgical presentation of columellar features, nostril anatomy and alveolar alignment in BCLP after infant orthopedics with and without nasoalveolar molding.

The Cleft Palate-Craniofacial Journal — Fri, 07 Oct 2011 04:00:00 +0100

Conclusions: Infants who received NAM had longer columellae and better aligned alveolar segments than those who received only IO. Other nostril dimensions were not significantly different. Key Words: BCLP, columella, NAM, presurgical orthopedics. PMID: 21981581 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

Development, characterisation and optimisation of poly(methylmethacrylate) bone cement formulations for appli-cation as a space maintainer in a staged strategy for cranio-facial bone regeneration

International Journal of Surgery — Thu, 06 Oct 2011 22:52:31 +0100

Delayed surgical reconstruction of craniofacial bony defects can lead to secondary intention healing, defect volume loss and soft-tissue fibrotic contracture, giving poorer aesthetic and functional results. Utilising temporary porous space maintainers, made by leaching porogens (pore inducers) from curable matrices e.g. Poly (methylmethacrylate) (PMMA) cement, limits aforementioned complications. (Source: International Journal of Surgery)

Esthesioneuroblastoma chemotherapy and radiotherapy for extensive disease: a case report

World Journal of Surgical Oncology — Wed, 05 Oct 2011 04:00:00 +0100

We report the case of a 48 years old man who consulted us with a 2-year history of progressive nasal obstruction, occasional epistaxis, facial pain, and watering of the eyes. A diagnosis of olfactory neuroblastoma was established by histopathology and confirmed by immunohistochemistry. On staging, the mass was classified as a Kadish stage C tumor with extensive involvement of the nasal cavities, nasopharynx, paranasal sinuses and orbit. Endoscopic excision of the mass was done. Traditionally the mainstay of treatment in such locally advanced patients is craniofacial resection followed by adjuvant radiotherapy. Our patient was treated with limited surgery and chemoradiation. Patient is free of recurrence at a follow-up of 5 years. This case report demonstrates the potential efficacy of plan...

MedWorm Sponsor Message: Find the best January Sales in the UK.

Vertical bone augmentation with 3D-synthetic monetite blocks in the rabbit calvaria.

Journal of Clinical Periodontology — Tue, 04 Oct 2011 04:00:00 +0100

CONCLUSION: Within the limits of our study, this novel material may be able to eliminate the need for autologous bone transplantation for the augmentation of large vertical bone defects. PMID: 22092695 [PubMed - as supplied by publisher] (Source: Journal of Clinical Periodontology)

Stem cells in bone regeneration