MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Acta Oncologica' source. Wed, 08 Feb 2012 08:41:14 +0100 http://www.medworm.com/index.php?rid=5625586&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248063%26dopt%3DAbstract Conclusions. The ratio between the relative risk in the highest and lowest county was basically similar when comparing counties of birth with counties of diagnosis. Thus, our data do not shed light on the relative contribution of risk factors acting early versus later in life. The incidence rate of TGCC in Norway is among the highest in the world, and the increase in incidence rate does not seem to level off. PMID: 22248063 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625586 Wed, 25 Jan 2012 07:37:27 +0100 5625586 http://www.medworm.com/index.php?rid=5625580&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22263970%26dopt%3DAbstract Authors: Dahl O, Brydøy M PMID: 22263970 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625580 Wed, 25 Jan 2012 07:36:29 +0100 5625580 http://www.medworm.com/index.php?rid=5625579&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22263971%26dopt%3DAbstract Conclusion. Low participation in group interventions may be more strongly associated with psychological characteristics than sociodemographic and medical factors. It seems that patients know to perceive whether their personal resources are inadequate for facing a life-threatening illness. Like individual therapy, group interventions should be more sensitive to perceived individual needs and to the art of tailoring suitable contents according individual needs. PMID: 22263971 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625579 Wed, 25 Jan 2012 07:36:20 +0100 5625579 http://www.medworm.com/index.php?rid=5625578&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22263972%26dopt%3DAbstract Authors: Petersen S, Würschmidt F, Gaul H, Caselitz J, Schwenk W PMID: 22263972 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625578 Wed, 25 Jan 2012 07:36:11 +0100 5625578 http://www.medworm.com/index.php?rid=5625583&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22263924%26dopt%3DAbstract Conclusion. Soft tissue tumour matching improved precision of treatment delivery in frameless SBRT of lung tumours compared to image guidance using bone matching. The intra-fractional displacement of the target position was affected by both translational and rotational changes in tumour baseline position relative to the bony anatomy and by changes in patient position. PMID: 22263924 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625583 Mon, 23 Jan 2012 05:00:00 +0100 5625583 http://www.medworm.com/index.php?rid=5625582&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22263925%26dopt%3DAbstract Conclusion. SBRT in adrenal gland metastasis is feasible without significant acute and late toxicities, with a good rate of local control. New SBRT fractionation schemes and the possibility to combine new systemic approaches should be investigated in order to further increase local control and reduce systemic disease progression. PMID: 22263925 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625582 Mon, 23 Jan 2012 05:00:00 +0100 5625582 http://www.medworm.com/index.php?rid=5625581&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22263926%26dopt%3DAbstract Conclusion. Higher rates of FFLP were achieved by SBRT in the treatment of primary liver malignancies with low toxicity. PMID: 22263926 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625581 Mon, 23 Jan 2012 05:00:00 +0100 5625581 http://www.medworm.com/index.php?rid=5625587&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248062%26dopt%3DAbstract Conclusion. Preoperative high-dose RT and concomitant UFT with increasing doses of Ox up to 60 mg/m(2)/week was feasible with low toxicity, high ypCR rates and promising OS in patients with non-resectable LARC. PMID: 22248062 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625587 Tue, 17 Jan 2012 05:00:00 +0100 5625587 http://www.medworm.com/index.php?rid=5625585&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248064%26dopt%3DAbstract Conclusions. Using IMRT as reference for the VMAT optimization it was possible to implement VMAT in the clinic with no increase in estimated risk of RP. Thus, toxicity is not expected to be a hindrance to using VMAT and will profit from the shorter delivery time with VMAT compared to IMRT. PMID: 22248064 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625585 Tue, 17 Jan 2012 05:00:00 +0100 5625585 http://www.medworm.com/index.php?rid=5625584&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248089%26dopt%3DAbstract Conclusions. SBRT can safely and effectively treat painful RCC bony metastases. There appears to be a relationship between radiation dose and time to stable pain relief. PMID: 22248089 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5625584 Tue, 17 Jan 2012 05:00:00 +0100 5625584 http://www.medworm.com/index.php?rid=5579642&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22229745%26dopt%3DAbstract Conclusion. The present quality-control study is the first nationwide population-based study to assess diagnostics and treatment of STS. When referred to a specialised sarcoma centre even patients with inadequate surgery can achieve good local control. STS is a rare cancer and its treatment should be centralised in Finland, which has 5.4 million inhabitants and approximately 100 new STSs of extremities and trunk wall annually. PMID: 22229745 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5579642 Tue, 10 Jan 2012 05:00:00 +0100 5579642 http://www.medworm.com/index.php?rid=5579641&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22229746%26dopt%3DAbstract Authors: Fode MM, Hilberg O, Bendstrup E, Hager H, Iversen M PMID: 22229746 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5579641 Tue, 10 Jan 2012 05:00:00 +0100 5579641 http://www.medworm.com/index.php?rid=5579640&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22229747%26dopt%3DAbstract Authors: Lybol C, Ottevanger PB, Thomas CM, Sweep FC, Massuger LF PMID: 22229747 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5579640 Tue, 10 Jan 2012 05:00:00 +0100 5579640 http://www.medworm.com/index.php?rid=5579639&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22229748%26dopt%3DAbstract Conclusions. The prevalence of esophageal cancer during the pretreatment of HPC patients was 51.5%; this prevalence was higher than that in previous reports. We believe that the increasing proportion of superficial lesions (82.8%) detected using iodine staining and EGD may have led to the relatively high prevalence. FDG-PET/CT detected only 20.7% of the esophageal cancers, although FDG-PET/CT is capable of detecting unexpected primary malignant tumors other than esophageal cancer. PMID: 22229748 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5579639 Tue, 10 Jan 2012 05:00:00 +0100 5579639 http://www.medworm.com/index.php?rid=5564786&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22208782%26dopt%3DAbstract Conclusion. Our results support previous results showing that ([18F])FDG-PET/CT can distinguish a group of patients with worse prognosis after neoadjuvant chemotherapy in adenocarcinoma of the esophagus or esophagogastric junction. This information could offer a new independent preoperative marker of prognosis. PMID: 22208782 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5564786 Mon, 02 Jan 2012 05:00:00 +0100 5564786 http://www.medworm.com/index.php?rid=5537136&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22122695%26dopt%3DAbstract Conclusion. Guidelines for adjuvant chemotherapy in stage III colon cancer are generally well followed in daily practice. However, uncertainty remains regarding the optimal treatment of elderly patients and patients with comorbidities, which underscores the need for practical clinical trials including these patients. PMID: 22122695 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537136 Sat, 24 Dec 2011 22:34:33 +0100 5537136 http://www.medworm.com/index.php?rid=5537119&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150165%26dopt%3DAbstract Conclusion. Endocrine symptoms are very frequently appearing in patients with icGCTs and they can present long before neuroimaging verification of tumour is possible. It is of the outmost importance to have the diagnosis of icGCTs in mind when children, adolescents and young adults are presenting with endocrine irregularities, because most icGCTs are very sensitive to radiotherapy and chemotherapy, and early onset of treatment is important in order to minimize morbidity and mortality. PMID: 22150165 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537119 Sat, 24 Dec 2011 22:31:37 +0100 5537119 http://www.medworm.com/index.php?rid=5537118&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150166%26dopt%3DAbstract Conclusion. Although the standardized overall cancer incidence in this relatively young IDU cohort was similar to that in the general population, the risk of specific types of cancer was significantly increased, suggesting that IDU confers elevated risks for certain malignancies. These findings prompt further studies to investigate causative factors and suggest the need for surveillance among persons with a history of IDU. PMID: 22150166 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537118 Sat, 24 Dec 2011 22:31:28 +0100 5537118 http://www.medworm.com/index.php?rid=5537117&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150167%26dopt%3DAbstract Conclusion. The high accuracy of the data regarding oesophageal cancer resection in the Swedish Patient Registry stresses its appropriateness for research purposes. PMID: 22150167 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537117 Sat, 24 Dec 2011 22:31:18 +0100 5537117 http://www.medworm.com/index.php?rid=5537116&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150168%26dopt%3DAbstract Authors: Joensuu G, Joensuu T, Nupponen N, Ruutu M, Collan J, Pesonen S, Hemminki A PMID: 22150168 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537116 Sat, 24 Dec 2011 22:31:09 +0100 5537116 http://www.medworm.com/index.php?rid=5537113&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175251%26dopt%3DAbstract Authors: Partl R, Richtig E, Kapp KS PMID: 22175251 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537113 Mon, 19 Dec 2011 05:00:00 +0100 5537113 http://www.medworm.com/index.php?rid=5537112&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175252%26dopt%3DAbstract Conclusion. Overall, CT is the most commonly recommended and used imaging modality for OSCC. Despite availability of national guidelines the type and number of radiological examinations vary between centres within a country, but the implementation of a fast-track programme may facilitate fast access to imaging. The absence of uniform criteria for determining the lymph nodes of the neck as cN+ complicates the comparison of the accuracy of the imaging modalities. Well-defined radiological strategies and criteria are needed to optimise the radiological work-up in OSCC. PMID: 22175252 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537112 Mon, 19 Dec 2011 05:00:00 +0100 5537112 http://www.medworm.com/index.php?rid=5537111&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175253%26dopt%3DAbstract Conclusion. Many countries use a broad-spectrum β-lactam as initial therapy in FN. International experts are sceptic towards the Norwegian recommendations. We discuss the arguments for and against penicillin G plus an aminoglycoside in FN. The main arguments to continue the Norwegian treatment tradition are the satisfactory clinical results and the reason to believe that it contributes to the low levels of antibiotic resistance in Norway. PMID: 22175253 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537111 Mon, 19 Dec 2011 05:00:00 +0100 5537111 http://www.medworm.com/index.php?rid=5537110&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175254%26dopt%3DAbstract Conclusion. The population-based SWENOTECA strategy, selecting patients who do not respond adequately to primary standard-dose chemotherapy for immediate treatment intensification with HDCT, is feasible and might be advantageous. PMID: 22175254 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537110 Mon, 19 Dec 2011 05:00:00 +0100 5537110 http://www.medworm.com/index.php?rid=5537115&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22171586%26dopt%3DAbstract Conclusions. While we did not observe any differences in tumor features, BCP patients have poorer prognosis compared to age and stage-matched control. Further studies should try to elucidate reasons for such poor outcome. PMID: 22171586 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537115 Fri, 16 Dec 2011 05:00:00 +0100 5537115 http://www.medworm.com/index.php?rid=5537114&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22171587%26dopt%3DAbstract Conclusion. Respiratory gated radiotherapy during DIBH is a suitable technique for loco-regional breast irradiation even when IMC lymph nodes are included in the PTV. Cardiopulmonary doses are considerably decreased for all dose levels without compromising the dose coverage to PTV. PMID: 22171587 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537114 Fri, 16 Dec 2011 05:00:00 +0100 5537114 http://www.medworm.com/index.php?rid=5537124&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150114%26dopt%3DAbstract Cancer and "playing" with reality: Clinical guidance with the help of the intermediate area and disavowal. Acta Oncol. 2011 Dec 12; Authors: Salander P PMID: 22150114 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537124 Mon, 12 Dec 2011 05:00:00 +0100 5537124 http://www.medworm.com/index.php?rid=5537123&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150115%26dopt%3DAbstract Conclusion. In selected head and neck cancer patients who are estimated to have a low risk of cancer recurrence at the nodal levels I-II and who are treated with SMG-sparing IMRT the risk of cancer recurrence at the vicinity of the spared salivary glands is low. PMID: 22150115 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537123 Mon, 12 Dec 2011 05:00:00 +0100 5537123 http://www.medworm.com/index.php?rid=5537122&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150116%26dopt%3DAbstract Conclusion. This review examines the existing role of denosumab in the treatment of bone complications of breast cancer and its potential role as adjuvant therapy. PMID: 22150116 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537122 Mon, 12 Dec 2011 05:00:00 +0100 5537122 http://www.medworm.com/index.php?rid=5537121&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150117%26dopt%3DAbstract Authors: Penna G, Allegra A, Romeo G, Alonci A, Cannavò A, Russo S, D'Angelo A, Petrungaro A, Musolino C PMID: 22150117 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537121 Mon, 12 Dec 2011 05:00:00 +0100 5537121 http://www.medworm.com/index.php?rid=5537120&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150118%26dopt%3DAbstract Authors: Savas S Abstract Introduction. Angiogenesis causes local growth, aggressiveness and metastasis in solid tumors, and thus, is almost always associated with poor prognosis and survival in cancer patients. Because of this clinical importance, several chemotherapeutic agents targeting angiogenesis have also been developed. Genes and genetic variations in angiogenesis/VEGF pathway thus may be correlated with clinical outcome in cancer patients. Material and methods. Here, we describe a manually curated public database, dbANGIO, which posts the results of studies testing the possible correlation of genetic variations (polymorphisms and mutations) from the angiogenesis/VEGF pathway with demographic features, clinicopathological features, treatment response and toxicity, and progn... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537120 Mon, 12 Dec 2011 05:00:00 +0100 5537120 http://www.medworm.com/index.php?rid=5537128&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150076%26dopt%3DAbstract Conclusions. Declines in earnings after cancer are to a large degree compensated by the Norwegian welfare state, and incomes overall are only modestly decreased among cancer survivors compared to the general population. Persons with multiple unfavorable sociodemographic characteristics experience particularly low incomes after cancer. This is of concern in a supposedly egalitarian society with public health care and antidiscrimination acts in place. Welfare state interventions, i.e. work reintegration efforts and/or compensations for labor earning drops, directed specifically towards these subgroups might be warranted. PMID: 22150076 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537128 Wed, 07 Dec 2011 05:00:00 +0100 5537128 http://www.medworm.com/index.php?rid=5537127&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150077%26dopt%3DAbstract Conclusion. This study confirms that imatinib efficacy is dependent on genotype in Korean GIST patients, consistent with results demonstrated by Western patients with GIST. PMID: 22150077 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537127 Wed, 07 Dec 2011 05:00:00 +0100 5537127 http://www.medworm.com/index.php?rid=5537126&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150078%26dopt%3DAbstract Conclusion. This study has shown possible common genetic events linking tumourigenicity and radiation response. The PLAU and PLAUR genes are involved in apoptosis evasion while the genes TIMP3, MMP1 and LOX are involved in regulation of the surrounding matrix. The first group may contribute to the difference in radiation resistance observed and the latter could be a major contributor to the tumourigenic capabilities by degrading the intercellular matrix. These results also indicate that cancer stem cells are more radiation resistant than stem cells of the same origin. PMID: 22150078 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537126 Wed, 07 Dec 2011 05:00:00 +0100 5537126 http://www.medworm.com/index.php?rid=5537125&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22150079%26dopt%3DAbstract Conclusion. Local excision may be an appropriate option for selected patients developing good clinical response after LCPRT. In our opinion, a policy of clinical observation in complete clinical responders after LCPRT may not be a safe strategy, unless we had robust predictive models for accurate identification of pathological complete response. In order to identify patients that may be potentially appropriate for such an approach we propose a clinical algorithm incorporating important clinical, radiological, and pathological parameters. The proposed model will require validation in a prospective study. Finally, we need randomised data for demonstrating the non-inferiority of clinical observation compared to conventional surgery before this can be considered as standard possible therapeuti... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537125 Wed, 07 Dec 2011 05:00:00 +0100 5537125 http://www.medworm.com/index.php?rid=5537129&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136073%26dopt%3DAbstract Authors: Cramer H, Lange S, Klose P, Paul A, Dobos G PMID: 22136073 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537129 Mon, 05 Dec 2011 05:00:00 +0100 5537129 http://www.medworm.com/index.php?rid=5537131&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132746%26dopt%3DAbstract Authors: Munshi A, Prabhu A, Kunkler I PMID: 22132746 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537131 Thu, 01 Dec 2011 05:00:00 +0100 5537131 http://www.medworm.com/index.php?rid=5537130&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132747%26dopt%3DAbstract Conclusions. Bladder volume is a significant factor affecting OP rates. However, our results suggest that bladder volumes exceeding 150 ml may not help meet planning dose constraints. PMID: 22132747 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537130 Thu, 01 Dec 2011 05:00:00 +0100 5537130 http://www.medworm.com/index.php?rid=5537135&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22129357%26dopt%3DAbstract Conclusions. Several clinical factors were associated with ER assay concordance. Some women were ineffectively treated with tamoxifen, or required but did not receive tamoxifen. We observed almost exactly the protective effect of endocrine therapy among tamoxifen-treated ER + women whose tumors expressed the ER on re-assay, compared with those ER- on re-assay. Diagnostic pathology results for ER + tumors appear a valid and useful resource for research studies. However, those for ER- tumors have lower validity. Study-specific considerations regarding the aims, diagnostic period, and consequences of including ER- patients with truly ER + disease ought to be examined when using diagnostic pathology results for ER- tumors in research studies. PMID: 22129357 [PubMed - as supplied by publish... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537135 Wed, 30 Nov 2011 05:00:00 +0100 5537135 http://www.medworm.com/index.php?rid=5537134&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22129358%26dopt%3DAbstract Conclusion. The results show that TAs are an issue in breast and gynaecological cancer patients receiving different chemotherapy regimens. There is a need for a more systematic investigation of TAs in chemotherapy patients in general as well as the need to address this issue in clinical practice. PMID: 22129358 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537134 Wed, 30 Nov 2011 05:00:00 +0100 5537134 http://www.medworm.com/index.php?rid=5537133&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22129359%26dopt%3DAbstract Authors: Stravodimou A, Voutsadakis IA PMID: 22129359 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537133 Wed, 30 Nov 2011 05:00:00 +0100 5537133 http://www.medworm.com/index.php?rid=5537132&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22129360%26dopt%3DAbstract Authors: Ma AT, Chan WK, Ma ES, Cheng T, Cheng PN PMID: 22129360 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537132 Wed, 30 Nov 2011 05:00:00 +0100 5537132 http://www.medworm.com/index.php?rid=5537137&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22103591%26dopt%3DAbstract Authors: Szturz P, Adam Z, Rehák Z, Koukalová R, Slaisová R, Stehlíková O, Chovancová J, Klabusay M, Krejčí M, Pour L, Hájek R, Mayer J PMID: 22103591 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537137 Mon, 21 Nov 2011 05:00:00 +0100 5537137 http://www.medworm.com/index.php?rid=5537138&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22098601%26dopt%3DAbstract The objective of this paper is to analyse long-term survival as well as staging and treatment patterns of CRC in Estonia. Material and methods. The analysis included all incident cases of CRC diagnosed in Estonia in 1997 (n = 546), identified through the Estonian Cancer Registry and followed up for 10 years after diagnosis. Staging and treatment data were retrospectively collected from medical records. Relative survival rate (RSR) was used to estimate the outcome. Results and conclusion. The 5-year RSR was 51% for colon cancer and 38% for rectal cancer; the corresponding 10-year RSR was 50% and 39%. We observed no excess mortality for early disease. For stages II and III, the survival was markedly higher in colon cancer (5-year RSR 79% and 66%, respectively) compared to rectal cancer (66% ... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5537138 Fri, 18 Nov 2011 05:00:00 +0100 5537138 http://www.medworm.com/index.php?rid=5426047&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085338%26dopt%3DAbstract Conclusion. The use of the bevacizumab increases the risk of treatment-related deaths and several grade 3 or 4 AEs in patient with NSCLC. The risk may be dose-dependent. Close monitoring and adequate management are recommended to decrease severe AEs. PMID: 22085338 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5426047 Wed, 16 Nov 2011 05:00:00 +0100 5426047 http://www.medworm.com/index.php?rid=5426046&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085375%26dopt%3DAbstract Conclusions. Thirty-one percent of locally advanced patients having NSCLC treated with docetaxel and cisplatin and concurrent thoracic radiation survived beyond five years. Progression-free patients might be cautiously followed up taking precautions against emerging pneumonia. PMID: 22085375 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5426046 Wed, 16 Nov 2011 05:00:00 +0100 5426046 http://www.medworm.com/index.php?rid=5426048&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22070666%26dopt%3DAbstract Discussion. Treatment of peritoneal carcinomatosis from gastric cancer is costly irrespective of treatment modality. If the survival benefit from adding loco-regional treatment to systemic chemotherapy indicated from this comparison is true, the incremental cost is considered high. PMID: 22070666 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5426048 Thu, 10 Nov 2011 05:00:00 +0100 5426048 http://www.medworm.com/index.php?rid=5426050&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22067021%26dopt%3DAbstract Conclusions. Patients with tumors expressing ghrelin had 2.5?3 times lower risk for recurrence or breast cancer death than those lacking ghrelin expression. Ghrelin expression is easily assessable with high reproducibility using immunohistochemistry. Further investigations are needed to establish the clinical significance of ghrelin as a biomarker in breast cancer. PMID: 22067021 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5426050 Wed, 09 Nov 2011 05:00:00 +0100 5426050 http://www.medworm.com/index.php?rid=5426049&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22070651%26dopt%3DAbstract Authors: Musolino C, Allegra A, Ferraro M, Aguennouz M, Russo S, Alonci A, Saitta S, Gangemi S PMID: 22070651 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5426049 Wed, 09 Nov 2011 05:00:00 +0100 5426049 http://www.medworm.com/index.php?rid=5426052&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22060134%26dopt%3DAbstract Conclusion. Dose calculations with the Acuros XB algorithm in homogeneous media are in good agreement with both measurements and the AAA algorithm. In heterogeneous media, the Acuros XB algorithm is superior to AAA in both lung and bony material. PMID: 22060134 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5426052 Mon, 07 Nov 2011 05:00:00 +0100 5426052 http://www.medworm.com/index.php?rid=5426051&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22060135%26dopt%3DAbstract Authors: Mahta A, Borys E, Kanakamedala MR, Kesari S PMID: 22060135 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5426051 Mon, 07 Nov 2011 05:00:00 +0100 5426051 http://www.medworm.com/index.php?rid=5382515&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22047060%26dopt%3DAbstract Discussion. Based on the present analysis of the comparability, completeness, validity and timeliness of premalignant lesions of vulva and vagina, we conclude that the Cancer Registry of Norway is able to monitor such premalignant lesions satisfactorily. PMID: 22047060 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382515 Wed, 02 Nov 2011 04:00:00 +0100 5382515 http://www.medworm.com/index.php?rid=5382514&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22047061%26dopt%3DAbstract Conclusion. The established model of columnar recombination reproduces the experimental data well, whereas the extensions using track structure models do not show such an agreement. Additionally, the effect of initial recombination on the saturation curve (i.e. Jaffé plot) does not follow a linear behavior as suggested by current dosimetry protocols, therefore higher order corrections (such as the investigated ones) might be necessary. PMID: 22047061 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382514 Wed, 02 Nov 2011 04:00:00 +0100 5382514 http://www.medworm.com/index.php?rid=5382521&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023114%26dopt%3DAbstract Authors: Glimelius B PMID: 22023114 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382521 Tue, 01 Nov 2011 04:00:00 +0100 5382521 http://www.medworm.com/index.php?rid=5382520&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023115%26dopt%3DAbstract Conclusion. Securin expression in rectal cancer is significantly reduced after RT. High securin expression and poor TRG after long-course (chemo)RT are indicators of unfavourable disease outcome. PMID: 22023115 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382520 Tue, 01 Nov 2011 04:00:00 +0100 5382520 http://www.medworm.com/index.php?rid=5382519&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023116%26dopt%3DAbstract Conclusion. The present nationwide and population-based study is our second report of treatment and prognosis of osteosarcoma in Finland. With modern chemotherapy the prognosis of local osteosarcoma has improved in Finland from 47% during 1971-1980 and 65% during 1981-1990 at five years to the present 73% during 1991-2005 at 10 years. The 10-year sarcoma-specific survival of 73% is excellent and comparable to results reported with contemporary treatment protocols in high-volume centers. However, improvement in limb-salvage rate and local control probably requires centralization of treatment of this rare disease. PMID: 22023116 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382519 Tue, 01 Nov 2011 04:00:00 +0100 5382519 http://www.medworm.com/index.php?rid=5382518&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023117%26dopt%3DAbstract Authors: Verhoeven RH, Kiemeney LA, Coebergh JW, Weiderpass E, Kjaerheim K, Martinsen JI, Lynge E, Pukkala E PMID: 22023117 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382518 Tue, 01 Nov 2011 04:00:00 +0100 5382518 http://www.medworm.com/index.php?rid=5382517&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22035117%26dopt%3DAbstract Conclusion. Household size, socioeconomic position and use of healthcare services were determinants of participation in mammography screening. This study emphasises the need for conducting refined analyses distinguishing among subgroups within diverse populations when explaining differences in screening behaviour. PMID: 22035117 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382517 Sun, 30 Oct 2011 04:00:00 +0100 5382517 http://www.medworm.com/index.php?rid=5382516&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22035118%26dopt%3DAbstract Conclusion. The individualized delivered treatment plans ensured that doses to OARs were within acceptable limits. This was not the case in 42% of the corresponding standard plans. Further optimized treatment plans were found to give an overall better dose coverage. In lack of MR capacity, it may be favorable to use CT for planning due to possible protection of OARs. The CT based target volumes were, however, not equivalent to the volumes described in magnetic resonance imaging (MRI) based recommendations. Prescription and assessment of dose, when introducing such target volumes, should be evaluated and preferably compared to well known treatment regimens. PMID: 22035118 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382516 Sun, 30 Oct 2011 04:00:00 +0100 5382516 http://www.medworm.com/index.php?rid=5382524&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023087%26dopt%3DAbstract Conclusion. Employment of a fast track five day staging strategy in patients with esophageal carcinoma is feasible. Definite TNM stage and treatment proposal can be achieved in 60% of cases, but comes at the expense of test overuse in about one fifth of patients. PMID: 22023087 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382524 Mon, 24 Oct 2011 04:00:00 +0100 5382524 http://www.medworm.com/index.php?rid=5382523&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023088%26dopt%3DAbstract Authors: Constantinidou A, Jones RL, Olmos D, Thway K, Fisher C, Al-Muderis O, Judson I PMID: 22023088 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382523 Mon, 24 Oct 2011 04:00:00 +0100 5382523 http://www.medworm.com/index.php?rid=5382522&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023089%26dopt%3DAbstract Conclusions. Period, rather than cohort, survival analysis should be used if the primary aim is to predict the future survival of recently diagnosed patients. Recently diagnosed cancer patients can, for many forms of cancer, expect an improved survival compared to patients diagnosed only a few years earlier. PMID: 22023089 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382522 Mon, 24 Oct 2011 04:00:00 +0100 5382522 http://www.medworm.com/index.php?rid=5382526&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017238%26dopt%3DAbstract Authors: Wibom C, Sjöström S, Henriksson R, Brännström T, Broholm H, Rydén P, Johansen C, Collatz-Laier H, Hepworth S, McKinney PA, Bethke L, Houlston RS, Andersson U, Melin BS Abstract Abstract Patient outcome from glioma may be influenced by germline variation. Considering the importance of DNA repair in cancer biology as well as in response to treatment, we studied the relationship between 1458 SNPs, which captured the majority of the common genetic variation in 136 DNA repair genes, in 138 glioblastoma samples from Sweden and Denmark. We confirmed our findings in an independent cohort of 121 glioblastoma patients from the UK. Our analysis revealed nine SNPs annotating MSH2, RAD51L1 and RECQL4 that were significantly (p < 0.05) associated with glioblastoma survival. ... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382526 Fri, 21 Oct 2011 04:00:00 +0100 5382526 http://www.medworm.com/index.php?rid=5382525&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017239%26dopt%3DAbstract Discussion. The combination of erlotinib and bevacizumab is well tolerated, however, with low clinical activity in patients with chemoresistant UGI cancer. Some patients do benefit from the therapy, and uPAR forms are potential biomarkers in these patients. PMID: 22017239 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382525 Fri, 21 Oct 2011 04:00:00 +0100 5382525 http://www.medworm.com/index.php?rid=5382527&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21995527%26dopt%3DAbstract Conclusion. CRAds carrying IL-24 may prove a novel and effective approach for the treatment of cancers. PMID: 21995527 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5382527 Thu, 13 Oct 2011 04:00:00 +0100 5382527 http://www.medworm.com/index.php?rid=5315151&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985131%26dopt%3DAbstract Conclusions. The NI was an independent predictor of compromised lymph nodes, taking into the consideration tumor size and histological grade. The genes identified here that integrate our "Nodal Index" model are predictive of lymph node metastasis in OSCC. PMID: 21985131 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5315151 Mon, 10 Oct 2011 04:00:00 +0100 5315151 http://www.medworm.com/index.php?rid=5315150&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985132%26dopt%3DAbstract Conclusions. Only a minority of the patients who started an endocrine therapy were actually eligible for an ET. Patients who were offered/recommended an ET had a high rate of compliance and persistence. Efforts should be made to make sure that all physicians, above all general practitioners, who are involved in the treatment of BC patients, are provided with current therapy guidelines as to guarantee an optimal patient management. PMID: 21985132 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5315150 Mon, 10 Oct 2011 04:00:00 +0100 5315150 http://www.medworm.com/index.php?rid=5282873&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21961497%26dopt%3DAbstract Conclusion. With most patients it is safe to estimate absorbed doses to kidneys, liver and spleen from 24 h activity concentration assuming an unchanged effective half-life during therapy. Patients with risk factors for kidney dysfunction need to be monitored in more detail. Simplified dosimetry based on the assumption of unchanged effective half-life can function as guidance to the number of therapy cycles an individual patient can tolerate. PMID: 21961497 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5282873 Mon, 03 Oct 2011 04:00:00 +0100 5282873 http://www.medworm.com/index.php?rid=5282871&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21961498%26dopt%3DAbstract Authors: Simon M, Bioulac-Sage P, Trillaud H, Blanc JF PMID: 21961498 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5282871 Mon, 03 Oct 2011 04:00:00 +0100 5282871 http://www.medworm.com/index.php?rid=5282870&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21961499%26dopt%3DAbstract Conclusion. The reference values provided can be used as a surrogate baseline measure in HRQL research, and when evaluating the effect of interventions on HRQL in cancer patients. PMID: 21961499 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5282870 Mon, 03 Oct 2011 04:00:00 +0100 5282870 http://www.medworm.com/index.php?rid=5249541&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21936753%26dopt%3DAbstract Conclusion. The combination of capecitabine and bevacizumab was safe with an acceptable toxicity profile and induced a significant rate of disease control in heavily pre-treated patients with metastatic colorectal cancer. PMID: 21936753 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5249541 Thu, 22 Sep 2011 04:00:00 +0100 5249541 http://www.medworm.com/index.php?rid=5249540&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21936754%26dopt%3DAbstract Authors: Shah BK, O'Keefe S PMID: 21936754 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5249540 Thu, 22 Sep 2011 04:00:00 +0100 5249540 http://www.medworm.com/index.php?rid=5249539&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21936755%26dopt%3DAbstract Authors: Declerck L, Adenis C, Amela E, Caty A, Adenis A, Penel N PMID: 21936755 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5249539 Thu, 22 Sep 2011 04:00:00 +0100 5249539 http://www.medworm.com/index.php?rid=5249538&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21936756%26dopt%3DAbstract Authors: Lilleby W, Willoch F, Stensvold A PMID: 21936756 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5249538 Thu, 22 Sep 2011 04:00:00 +0100 5249538 http://www.medworm.com/index.php?rid=5249542&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21923569%26dopt%3DAbstract Conclusion. This prospective randomised trial of support group intervention in a large homogenous group of breast cancer women showed a statistically significant effect on lowering anxiety over time. No statistically significant effect of intervention could be seen on depression. PMID: 21923569 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5249542 Mon, 19 Sep 2011 04:00:00 +0100 5249542 http://www.medworm.com/index.php?rid=5220762&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21879835%26dopt%3DAbstract Conclusion. An adrenal lesion occurring in a patient with past malignancy has a high likelihood of representing a benign lesion, and even in patients with present signs of malignant disease at least one fourth to one half of such lesions are benign. Dedicated adrenal imaging including computed tomography attenuation measurements with wash-out characteristics, in addition to biochemical testing for adrenal dysfunction, is highly recommended in these cases, especially in patients without any other signs of metastatic spread. PMID: 21879835 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5220762 Wed, 31 Aug 2011 04:00:00 +0100 5220762 http://www.medworm.com/index.php?rid=5179888&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21871002%26dopt%3DAbstract Discussion. HT was definitely associated with PTC as was chronic inflammation with cancer in other locations. Interestingly, however, the coexistence of HT in PTC cases introduced favourable clinical outcomes compared with those of PTC without HT. PMID: 21871002 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5179888 Sat, 27 Aug 2011 23:00:00 +0100 5179888 http://www.medworm.com/index.php?rid=5179887&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21871003%26dopt%3DAbstract Conclusions. The proposed approach offers the possibility of improved treatment results as it takes into consideration the heterogeneity and the dynamics of the hypoxic regions. It also provides early identification of the clinical cases that might benefit from dose escalation as well as the cases that could benefit from other counter-hypoxic measures. PMID: 21871003 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5179887 Sat, 27 Aug 2011 23:00:00 +0100 5179887 http://www.medworm.com/index.php?rid=5179886&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21871004%26dopt%3DAbstract Conclusions. The data in the screening register has high coverage and is thus useful for statistical and evaluation purposes. However, in order to improve the accuracy of diagnostic information, there are grounds to consider data retrieval through systematic linkage to other health care registers. PMID: 21871004 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5179886 Sat, 27 Aug 2011 23:00:00 +0100 5179886 http://www.medworm.com/index.php?rid=5179885&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21871005%26dopt%3DAbstract Conclusion. Contemporary RT has limited early effects on HRQOL. V40 is a significant predictor of RT-related fatigue. PMID: 21871005 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5179885 Sat, 27 Aug 2011 23:00:00 +0100 5179885 http://www.medworm.com/index.php?rid=5179884&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21871006%26dopt%3DAbstract Authors: Dantas FE, de Almeida Vieira CA, de Castro CC, Neto GC, Matos DM PMID: 21871006 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5179884 Sat, 27 Aug 2011 23:00:00 +0100 5179884 http://www.medworm.com/index.php?rid=5160064&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21864048%26dopt%3DAbstract Authors: Becker-Schiebe M, Hannig H, Hoffmann W, Donhuijsen K PMID: 21864048 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160064 Tue, 23 Aug 2011 23:00:00 +0100 5160064 http://www.medworm.com/index.php?rid=5160063&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21864049%26dopt%3DAbstract Conclusion. Individuals who attend cancer genetic counseling do not suffer more anxiety or depression compared to all other cancer-related groups. However, some counselees might need additional sessions and extended support. Thus, identifying extremely worried individuals who need more support, and allocating further resources to their care, seems to be more sufficient. PMID: 21864049 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160063 Tue, 23 Aug 2011 23:00:00 +0100 5160063 http://www.medworm.com/index.php?rid=5160062&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21864050%26dopt%3DAbstract Conclusion. Citrulline-based assessment scores are objective and should be considered in measuring radiation-induced intestinal toxicity. PMID: 21864050 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160062 Tue, 23 Aug 2011 23:00:00 +0100 5160062 http://www.medworm.com/index.php?rid=5160066&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21861595%26dopt%3DAbstract Authors: Guo W, Liu X, Gao H PMID: 21861595 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160066 Mon, 22 Aug 2011 23:00:00 +0100 5160066 http://www.medworm.com/index.php?rid=5160065&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21861596%26dopt%3DAbstract Conclusion. The individual-centered approach is a well-suited innovative concept to increase the knowledge regarding the relationship between cancer and suicide. We found a two to seven times higher suicide rate than those reported in epidemiologic studies. The population-based approach can barely elucidate the immense variety of one of the most personal decisions: the act of intentionally ending one's own life. These studies suffer from systematic failure of analysis since they did not a) consider the potential confounding role of comorbid medical and/or psychiatric conditions, and b) report in which disease stage suicide was committed, since the decisive disease-related event whether and when metastatic disease occurred was not recorded. Furthermore, epidemiologic data stems from countri... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160065 Mon, 22 Aug 2011 23:00:00 +0100 5160065 http://www.medworm.com/index.php?rid=5160070&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859353%26dopt%3DAbstract Authors: Jorsal T, Rørth M PMID: 21859353 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160070 Sun, 21 Aug 2011 23:00:00 +0100 5160070 http://www.medworm.com/index.php?rid=5160069&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859354%26dopt%3DAbstract Authors: Karadeniz C, Köse F, Abali H, Sümbül AT, Oğuzkurt L, Karabacak T, Oberg K PMID: 21859354 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160069 Sun, 21 Aug 2011 23:00:00 +0100 5160069 http://www.medworm.com/index.php?rid=5160068&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859355%26dopt%3DAbstract Authors: Melichar B, Laco J, Fridrichová P, Simkovič M, Papajík T, Foretová L PMID: 21859355 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160068 Sun, 21 Aug 2011 23:00:00 +0100 5160068 http://www.medworm.com/index.php?rid=5160067&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859356%26dopt%3DAbstract Authors: Munshi A PMID: 21859356 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160067 Sun, 21 Aug 2011 23:00:00 +0100 5160067 http://www.medworm.com/index.php?rid=5160073&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851185%26dopt%3DAbstract Conclusion. An intensified regimen of concomitant boost radiotherapy plus concurrent raltitrexed and oxaliplatin, can be safely administered in patients with locally advanced rectal cancer. This regimen produces high rates of pathological complete response. Based on available data, this type of treatment could be offered to patients with more advanced tumors (T4 or local recurrence). PMID: 21851185 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160073 Wed, 17 Aug 2011 23:00:00 +0100 5160073 http://www.medworm.com/index.php?rid=5160072&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851186%26dopt%3DAbstract Conclusion. Testicular-cancer survivors in Sweden who have received five or more cycles of cisplatin-based chemotherapy experience an increased incidence of long-term compromised language; the effect is primarily seen among men with a low level of education. PMID: 21851186 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160072 Wed, 17 Aug 2011 23:00:00 +0100 5160072 http://www.medworm.com/index.php?rid=5160071&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851187%26dopt%3DAbstract Authors: Shai A, Leitzin L, Steiner M, Peer A, Srour S, Shalom RB PMID: 21851187 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5160071 Wed, 17 Aug 2011 23:00:00 +0100 5160071 http://www.medworm.com/index.php?rid=5142372&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21830994%26dopt%3DAbstract Conclusion. Concerns regarding less extensive treatment in MBC patients were not supported by this study. Although no differences in the stage of the disease or treatment intensity could be demonstrated, outcome was inferior in the male group. PMID: 21830994 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5142372 Wed, 10 Aug 2011 23:00:00 +0100 5142372 http://www.medworm.com/index.php?rid=5142371&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21830995%26dopt%3DAbstract Conclusion. The example of Norway illustrates that although monitoring of screening outcome is highly warranted, this may be seriously jeopardized if use of mammography examinations was widespread prior to implementation of an organized program. PMID: 21830995 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5142371 Wed, 10 Aug 2011 23:00:00 +0100 5142371 http://www.medworm.com/index.php?rid=5142373&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21824038%26dopt%3DAbstract Conclusion. The introduction of G-CSF was justified because of the high incidence of FN. However, it could not have been predicted after reviewing the published literature. The incidence of non-hematological adverse events had been reported in some, but not all adjuvant taxanes studies. In the future, focus should be more on the side effects, especially when introducing new toxic systemic regimes. PMID: 21824038 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5142373 Mon, 08 Aug 2011 23:00:00 +0100 5142373 http://www.medworm.com/index.php?rid=5108181&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21812624%26dopt%3DAbstract Conclusions. These results, applied to further sites, should lead to investigation of differences in cancer control policies between regions. PMID: 21812624 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5108181 Tue, 02 Aug 2011 23:00:00 +0100 5108181 http://www.medworm.com/index.php?rid=5108180&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21812625%26dopt%3DAbstract Authors: Ozkan K, Sehsuvar G, Erdem C, Mustafa C, Ibrahim S, Fatih O PMID: 21812625 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5108180 Tue, 02 Aug 2011 23:00:00 +0100 5108180 http://www.medworm.com/index.php?rid=5108179&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21812626%26dopt%3DAbstract Conclusions. Underreporting of pancreatic cancer to the Swedish Cancer Register was pronounced and increased with older age. Less than 3% of patients with a record of pancreatic cancer both in the Cancer Register and the Patient Register survived five years or longer. PMID: 21812626 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5108179 Tue, 02 Aug 2011 23:00:00 +0100 5108179 http://www.medworm.com/index.php?rid=5063694&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767169%26dopt%3DAbstract Authors: Nyström H, Blomqvist E, Høyer M, Montelius A, Muren LP, Nilsson P, Taheri-Kadkhoda Z, Glimelius B PMID: 21767169 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063694 Tue, 26 Jul 2011 16:03:17 +0100 5063694 http://www.medworm.com/index.php?rid=5063693&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767170%26dopt%3DAbstract Authors: Liao Z, Lin SH, Cox JD Abstract The current standard treatment for lung cancer, the most common type of cancer worldwide, depends on disease stage. Surgery is the treatment of choice for early-stage tumors, but radiotherapy is a good option for those with early-stage tumors who cannot undergo surgery, and radiotherapy in conjunction with chemotherapy is the standard of care for locally advanced tumors. Although advances in photon (x-ray)-based radiotherapy involving three-dimensional conformal radiotherapy and intensity-modulated radiotherapy allow radiation doses to be escalated beyond the traditional limit of 60 Gy, this dose is not considered to be sufficient for tumor eradication. Moreover, the improvements in local control and survival conferred by concurrent chemotherapy... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063693 Tue, 26 Jul 2011 16:03:11 +0100 5063693 http://www.medworm.com/index.php?rid=5063692&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767171%26dopt%3DAbstract Authors: Sørensen BS, Overgaard J, Bassler N Abstract Background. In vitro RBE values for various high LET radiation types have been determined for many different cell types. Occasionally it is criticized that RBE for a given endpoint cannot be single-value dependent on LET alone, but also on particle species, due to the different dose deposition profiles on microscopic scale. Hence LET is not sufficient as a predictor of RBE, and this is one of the motivations for development of radiobiological models which explicitly depend on the detailed particle energy spectrum of the applied radiation field. The aim of the present study is to summarize the available data in the literature regarding the dependency of RBE on LET for different particles. Method. As RBE is highly dependent on cell t... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063692 Tue, 26 Jul 2011 16:03:06 +0100 5063692 http://www.medworm.com/index.php?rid=5063691&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767172%26dopt%3DAbstract Authors: Mendenhall NP, Malyapa RS, Su Z, Yeung D, Mendenhall WM, Li Z Abstract There is a strong rationale for potential benefits from proton therapy (PT) for selected cancers of the head and neck because of the opportunity to improve the therapeutic ratio by improving radiation dose distributions and because of the significant differences in radiation dose distribution achievable with x-ray-based radiation therapy (RT) and PT. Comparisons of dose distributions between x-ray-based and PT plans in selected cases show specific benefits in dose distribution likely to translate into improved clinical outcomes. However, the use of PT in head and neck cancers requires special considerations in the simulation and treatment planning process, and currently available PT technology may not permi... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063691 Tue, 26 Jul 2011 16:03:01 +0100 5063691 http://www.medworm.com/index.php?rid=5063690&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767173%26dopt%3DAbstract Conclusions. The low dose bath from highly conformal photon techniques may become relevant for lung toxicity when radiation is combined with cytotoxic chemotherapy as shown here. Proton therapy allows highly conformal delivery while minimizing the low dose bath potentially interacting with chemotherapy. Thus, intensive drug-radiation combinations could be an interesting indication for selecting patients for proton therapy. It is likely that the IMRT plans would perform better if the CERD was accounted for during optimization, but more clinical data is required to facilitate evidence-based plan optimization in the multi-modality setting. PMID: 21767173 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063690 Tue, 26 Jul 2011 16:02:58 +0100 5063690 http://www.medworm.com/index.php?rid=5063689&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767174%26dopt%3DAbstract Conclusion. The IMPT technique produced the most conform plans. For tumors located in the one of the cerebral hemispheres, the non-coplanar RA and the IMPT techniques were able to reduce doses to the contralateral hippocampus. The IMPT technique offered the largest sparing of the brain and fiber tracts. RA techniques tended to produce more conform target doses than IMRT. PMID: 21767174 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063689 Tue, 26 Jul 2011 16:02:53 +0100 5063689 http://www.medworm.com/index.php?rid=5063688&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767175%26dopt%3DAbstract Conclusion. The combination of photon IMRT and carbon ion boost is feasible in patients with intermediate-risk PC. So far, the treatment has been well tolerated. Acute toxicity rates were in good accordance with data reported for high dose IMRT alone. PMID: 21767175 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063688 Tue, 26 Jul 2011 16:02:49 +0100 5063688 http://www.medworm.com/index.php?rid=5063687&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767176%26dopt%3DAbstract Conclusion. This case study shows that RT with protons were far less robust to anatomical changes than when treated with photons, emphasising the increased need for adaptive approaches in RT with protons. PMID: 21767176 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063687 Tue, 26 Jul 2011 16:02:45 +0100 5063687 http://www.medworm.com/index.php?rid=5063686&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767177%26dopt%3DAbstract Conclusions. We conclude that for ions with small total range (z(w-eq) ≤3 cm) dosimetry without applying FCF could in principle be performed in phantoms of materials other than water without a significant loss of accuracy. However, in clinical high-energy ion beams with penetration depths z(w-eq) ≥3 cm, where accurate positioning in water is not an issue, absorbed dose measurements should be directly performed in water or accurate values of FCF need to be established. PMID: 21767177 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063686 Tue, 26 Jul 2011 16:02:41 +0100 5063686 http://www.medworm.com/index.php?rid=5063685&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767178%26dopt%3DAbstract Conclusions. When comparing RA and 3D CRT treatment for pediatric MB it is a matter of comparing higher SC risk against higher risks of non-cancer adverse events. Considering time until onset of the different complications is necessary to fully assess patient benefit in such a comparison. The IMPT plans, including SN dose contribution, compared favorably to the photon techniques in terms of all radiobiological risk estimates. PMID: 21767178 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063685 Tue, 26 Jul 2011 16:02:36 +0100 5063685 http://www.medworm.com/index.php?rid=5063684&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767179%26dopt%3DAbstract Discussion. Alanine dosimeters, in combination with flux measurements and Monte Carlo calculations with FLUKA, suggest that it is possible to establish a system for monitoring the dose in a mixed neutron and gamma field for BNCT and other applications in radiotherapy. PMID: 21767179 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063684 Tue, 26 Jul 2011 16:02:30 +0100 5063684 http://www.medworm.com/index.php?rid=5063683&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767180%26dopt%3DAbstract Conclusion. A considerable sparing of normal liver tissue can be obtained using proton-based SBRT for solitary liver tumours. PMID: 21767180 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063683 Tue, 26 Jul 2011 16:02:24 +0100 5063683 http://www.medworm.com/index.php?rid=5063682&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767181%26dopt%3DAbstract Conclusions. Our study shows that Presage™ remains a dosimeter of interest for radiation therapy with other particles as well as photons in the therapy dose range. PMID: 21767181 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063682 Tue, 26 Jul 2011 16:02:19 +0100 5063682 http://www.medworm.com/index.php?rid=5063681&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767182%26dopt%3DAbstract Authors: Muren LP, Glimelius B PMID: 21767182 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063681 Tue, 26 Jul 2011 16:02:15 +0100 5063681 http://www.medworm.com/index.php?rid=5063680&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767183%26dopt%3DAbstract Authors: Schippers JM, Lomax AJ Abstract An increasing number of proton therapy facilities are being planned and built at hospital based centers. Most facilities are employing traditional dose delivery methods. A second generation of dose application techniques, based on pencil beam scanning, is slowly being introduced into the commercially available proton therapy systems. New developments in accelerator physics are needed to accommodate and fully exploit these new techniques. At the same time new developments such as the development of small cyclotrons, Dielectric Wall Accelerator (DWA) and laser driven systems, aim for smaller, single room treatment units. In general the benefits of proton therapy could be exploited optimally when achieving a higher level in accuracy, beam energy, b... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063680 Tue, 26 Jul 2011 16:02:11 +0100 5063680 http://www.medworm.com/index.php?rid=5063679&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767184%26dopt%3DAbstract Authors: Hutton BF Abstract Statistical iterative reconstruction is now widely used in clinical practice and has contributed to significant improvement in image quality in recent years. Although primarily used for reconstruction in emission tomography (both single photon emission computed tomography (SPECT) and positron emission tomography (PET)) there is increasing interest in also applying similar algorithms to x-ray computed tomography (CT). There is increasing complexity in the factors that are included in the reconstruction, a demonstration of the versatility of the approach. Research continues with exploration of methods for further improving reconstruction quality with effective correction for various sources of artefact. PMID: 21767184 [PubMed - in process] (Source: Acta On... Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063679 Tue, 26 Jul 2011 16:02:02 +0100 5063679 http://www.medworm.com/index.php?rid=5063678&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767185%26dopt%3DAbstract Conclusions. Intratumoral regions showing similar vascular properties could successfully be labeled in three distinct clusters and the volume fraction of one cluster region was associated with primary tumor control. PMID: 21767185 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063678 Tue, 26 Jul 2011 16:01:54 +0100 5063678 http://www.medworm.com/index.php?rid=5063677&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767186%26dopt%3DAbstract Conclusions. This study has shown that both the size and displacement of the FMAs increase in the PE direction on DW images. The larger shifts were observed for FMs positioned with the long axis orthogonal to the PE direction. Measurements obtained for different b-values gave consistent results. PMID: 21767186 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063677 Tue, 26 Jul 2011 16:01:50 +0100 5063677 http://www.medworm.com/index.php?rid=5063676&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767187%26dopt%3DAbstract Conclusions. DCECT and DPET gave similar temporal wash-in characteristics, and the images also showed a relatively high spatial correlation. Hence, if the limited spatial resolution of DPET is considered adequate, a single DPET scan only for assessing both tumor perfusion and metabolic activity may be considered. However, further work on a larger number of cases is needed to verify the correlations observed in the present study. PMID: 21767187 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063676 Tue, 26 Jul 2011 16:01:45 +0100 5063676 http://www.medworm.com/index.php?rid=5063675&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767188%26dopt%3DAbstract Conclusion. Dose-escalating only the PET-active areas of lung tumours to doses of 82 Gy while respecting normal tissue constraints is feasible, also in a series of unselected patients including cases with relatively large tumours. PMID: 21767188 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063675 Tue, 26 Jul 2011 16:01:39 +0100 5063675 http://www.medworm.com/index.php?rid=5063674&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767189%26dopt%3DAbstract Conclusion. The DR FDG-PET protocol is feasible and the BH images have a superior quality compared to the FB images. The protocol may also provide information of relevance for radiotherapy planning and follow-up. A patient trial is needed for assessing the clinical value of the imaging protocol. PMID: 21767189 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063674 Tue, 26 Jul 2011 16:01:32 +0100 5063674 http://www.medworm.com/index.php?rid=5063673&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767190%26dopt%3DAbstract Conclusion. The established method provides a means of using a (commercially available) DIR algorithm to obtain a quantitative measure of local lung volume change. With further phantom and patient validation studies, quantitative maps of specific ventilation should be possible to produce and use in a clinical setting. PMID: 21767190 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063673 Tue, 26 Jul 2011 16:01:27 +0100 5063673 http://www.medworm.com/index.php?rid=5063672&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767191%26dopt%3DAbstract Conclusions. Judged on parameters affecting the common diagnostic image properties, improved beam hardening and scatter correction diminishes the difference between CBCT and CT image quality considerably. In the pursuit of CBCT-based treatment adaptation, dedicated imaging protocols may be required. PMID: 21767191 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063672 Tue, 26 Jul 2011 16:01:21 +0100 5063672 http://www.medworm.com/index.php?rid=5063671&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767192%26dopt%3DAbstract Conclusions. DIR improved the performance of pelvic organ contour propagation from the pCT to CBCTs as compared to rigid registration only. Still, a large fraction of the propagated rectum and bladder contours were unacceptable. The image quality of the CBCTs was sub-optimal and the usability of CBCTs for dose accumulation and adaptation purposes is therefore likely to benefit from improved image quality and improvements of the DIR algorithm. PMID: 21767192 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063671 Tue, 26 Jul 2011 16:01:12 +0100 5063671 http://www.medworm.com/index.php?rid=5063670&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767193%26dopt%3DAbstract Conclusions. Positioning based on fiducials gave the best trade-off between coverage of the targets although resulting in the highest dose to rectum. Target underdosage occurred mostly in the seminal vesicles. For both targets, the best parameter to predict TUD was the relative volume. PMID: 21767193 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063670 Tue, 26 Jul 2011 16:01:02 +0100 5063670 http://www.medworm.com/index.php?rid=5063669&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767194%26dopt%3DAbstract Conclusion. For patient specific cases, the model can with good accuracy calculate 3D dose distributions both with and without respiratory motion, and evaluate the dosimetric effects. PMID: 21767194 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063669 Tue, 26 Jul 2011 16:00:49 +0100 5063669 http://www.medworm.com/index.php?rid=5063668&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767195%26dopt%3DAbstract Conclusions. DMLC tracking was integrated with a wired EM transponder localization system and investigated for arc and static field delivery. The system provides sub-mm geometrical errors for most trajectories. PMID: 21767195 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063668 Tue, 26 Jul 2011 16:00:39 +0100 5063668 http://www.medworm.com/index.php?rid=5063667&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767196%26dopt%3DAbstract Conclusion. kV and MV image-based DMLC tracking was successfully integrated with direct image access. It resulted in substantial tracking latency reductions compared with image-based tracking without direct image access. PMID: 21767196 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063667 Tue, 26 Jul 2011 16:00:34 +0100 5063667 http://www.medworm.com/index.php?rid=5063666&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767197%26dopt%3DAbstract Conclusions. An automated analysis of exposure index values, with the purpose of detecting changes in exposure, can be performed using the R software in combination with a DICOM header metadata repository containing the exposure index values from the images. The routine described has good sensitivity and acceptable specificity for a wide range of central body part projections and can be optimised for more specialised purposes. PMID: 21767197 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063666 Tue, 26 Jul 2011 16:00:30 +0100 5063666 http://www.medworm.com/index.php?rid=5063665&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767198%26dopt%3DAbstract Conclusion. The ACR method was feasible in quality assurance of a multi-unit imaging center and the ACR protocol could replace the MagNET phantom tests. An automatic analysis of the images will further improve cost-effectiveness and objectiveness of the ACR protocol. PMID: 21767198 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063665 Tue, 26 Jul 2011 16:00:21 +0100 5063665 http://www.medworm.com/index.php?rid=5063664&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767199%26dopt%3DAbstract Conclusions. In order to perform accurate tumour dosimetry in mouse models it is necessary to take the additional contribution from the activity distribution within the body of the mouse into account. This may be of significance in the interpretation of radiobiological tumour response in pre-clinical studies. PMID: 21767199 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063664 Tue, 26 Jul 2011 16:00:16 +0100 5063664 http://www.medworm.com/index.php?rid=5063663&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767200%26dopt%3DAbstract Conclusion. It is important to understand limitations in quantitative SPECT images and the reasons for apparent heterogeneities since these have an impact on dose-volume histograms. A MC-based dosimetry calculation from SPECT images is not always warranted. PMID: 21767200 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063663 Tue, 26 Jul 2011 16:00:12 +0100 5063663 http://www.medworm.com/index.php?rid=5063662&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21767201%26dopt%3DAbstract Authors: Tandstad T, Indrebø G PMID: 21767201 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063662 Sun, 17 Jul 2011 23:00:00 +0100 5063662 http://www.medworm.com/index.php?rid=5063697&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21745130%26dopt%3DAbstract Conclusion. The type of reconstruction had a significant long-term influence on patient satisfaction and the objective result. Women reconstructed with autologous tissue were significantly more pleased, and the objective outcome was assessed as superior. PMID: 21745130 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063697 Sun, 10 Jul 2011 23:00:00 +0100 5063697 http://www.medworm.com/index.php?rid=5063696&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21745131%26dopt%3DAbstract Conclusions. Patient volume or teaching status of a hospital did not have any impact on the prognosis of pre- or postmenopausal stage II breast cancer patients included in the adjuvant endocrine trials. Our data support the hypothesis that differences in survival related to patient volume at the treatment units may be explained by inappropriate adjuvant systemic treatment. PMID: 21745131 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063696 Sun, 10 Jul 2011 23:00:00 +0100 5063696 http://www.medworm.com/index.php?rid=5063695&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21745132%26dopt%3DAbstract Authors: Fumagalli I, Penel N, Wacrenier A, Bedoui SE, Adenis A PMID: 21745132 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5063695 Sun, 10 Jul 2011 23:00:00 +0100 5063695 http://www.medworm.com/index.php?rid=5011816&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21736502%26dopt%3DAbstract Conclusion. In conclusion, the present study confirms that high-dose TSEBT is an effective, but generally not a curative therapy in the management of CTCL. High-dose treatment yielded significantly better results than low-dose treatment with 4 Gy. TSEBT offers significant palliation in most patients when other skin-directed or systemic treatments have failed. PMID: 21736502 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011816 Thu, 07 Jul 2011 23:00:00 +0100 5011816 http://www.medworm.com/index.php?rid=5011815&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21736503%26dopt%3DAbstract Authors: Schaefer N, Rasch K, Moehlenbruch M, Urbach H, Stuplich M, Blasius E, Scheffler B, Herrlinger U, Glas M PMID: 21736503 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011815 Thu, 07 Jul 2011 23:00:00 +0100 5011815 http://www.medworm.com/index.php?rid=5011814&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21736504%26dopt%3DAbstract Conclusion. Temsirolimus appears feasible, safe and active in heavily pretreated patients. PMID: 21736504 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011814 Thu, 07 Jul 2011 23:00:00 +0100 5011814 http://www.medworm.com/index.php?rid=5011813&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21736506%26dopt%3DAbstract Conclusion. Our data suggest that PHF6 mutation might play a role in tumorigenesis not only of T-ALL, but also of AML and HCC. PMID: 21736506 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011813 Thu, 07 Jul 2011 23:00:00 +0100 5011813 http://www.medworm.com/index.php?rid=5011818&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21726177%26dopt%3DAbstract Conclusion. The prevalence of HPV16 and 18, followed by HPV33, 31 and 45 is high in SCC and ADC in the Stockholm region. Public HPV vaccination could potentially inhibit a large proportion of such tumours underlining the urgency to initiate HPV vaccination. PMID: 21726177 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011818 Mon, 04 Jul 2011 23:00:00 +0100 5011818 http://www.medworm.com/index.php?rid=5011817&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21726178%26dopt%3DAbstract Authors: Roca S, Quivy A, Gross-Goupil M, Bernhard JC, De Clermont H, Ravaud A PMID: 21726178 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011817 Mon, 04 Jul 2011 23:00:00 +0100 5011817 http://www.medworm.com/index.php?rid=5011819&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21718210%26dopt%3DAbstract Conclusion. All of this research is in its infancy - many problems still exist. Further studies are needed to search for specific targeted therapies for osteosarcoma, in-depth study of mechanism of drug resistance, identifying the role that CSCs play in tumor metastasis, and demonstrate the imbalance of specific pathways in osteosarcoma stem cells. PMID: 21718210 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011819 Thu, 30 Jun 2011 23:00:00 +0100 5011819 http://www.medworm.com/index.php?rid=5011821&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21714698%26dopt%3DAbstract Authors: Zukauskaite R, Hjorthgau K, Poulsen PL, Baerentzen S, Ladekarl M PMID: 21714698 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011821 Wed, 29 Jun 2011 23:00:00 +0100 5011821 http://www.medworm.com/index.php?rid=5011820&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21714699%26dopt%3DAbstract Authors: Lai HK, Law MF, Leung C, Yip SF, Ha CY, Chan HN, Ng C, Yeung YM PMID: 21714699 [PubMed - as supplied by publisher] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=5011820 Wed, 29 Jun 2011 23:00:00 +0100 5011820 http://www.medworm.com/index.php?rid=4876249&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21574833%26dopt%3DAbstract Conclusions. ECT is an efficient and safe treatment and clinicians should not hesitate to use it even in the elderly. PMID: 21574833 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=4876249 Sun, 29 May 2011 06:49:49 +0100 4876249 http://www.medworm.com/index.php?rid=4876248&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21574834%26dopt%3DAbstract Authors: Harris SJ, Seah JA, Barnett F, White SC PMID: 21574834 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=4876248 Sun, 29 May 2011 06:49:40 +0100 4876248 http://www.medworm.com/index.php?rid=4876245&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21604932%26dopt%3DAbstract Authors: Nilsson S, Andersson L PMID: 21604932 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=4876245 Sun, 29 May 2011 06:49:01 +0100 4876245 http://www.medworm.com/index.php?rid=4876244&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21604933%26dopt%3DAbstract Authors: Holmberg L, Akre O PMID: 21604933 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=4876244 Sun, 29 May 2011 06:48:56 +0100 4876244 http://www.medworm.com/index.php?rid=4876243&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21604934%26dopt%3DAbstract Authors: Bul M, Schröder FH In 2009, the European Randomized Study of Screening for Prostate Cancer (ERSPC) was one of two studies to report interim data on the effect of screening for prostate cancer (PC) on the disease specific mortality. Contradictory results caused considerable discussion and misunderstanding in secondary literature. PMID: 21604934 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=4876243 Sun, 29 May 2011 06:48:51 +0100 4876243 http://www.medworm.com/index.php?rid=4876242&cid=s_31083_6_f&fid=31083&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21604935%26dopt%3DAbstract Authors: Berg CD The Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial (PLCO) was conducted in sites around USA during a period of marked secular changes in the use of prostate specific antigen (PSA) screening for prostate cancer. PMID: 21604935 [PubMed - in process] (Source: Acta Oncologica) Acta Oncologica journals http://www.medworm.com/rss/comments.php?id=4876242 Sun, 29 May 2011 06:48:39 +0100 4876242