MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Acta Orthopaedica' source. Thu, 09 Feb 2012 00:02:23 +0100 http://www.medworm.com/index.php?rid=5611560&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248163%26dopt%3DAbstract Authors: Bohm E, Petrak M, Gascoyne T, Turgeon T Abstract Background Previous in vitro research on addition of antibiotics to bone cement has found no statistically significant deterioration in mechanical properties. However, no clinical studies have compared the performance of tobramycin-laden bone cement with that of standard bone cement (Simplex P). Patients and Methods 23 patients (25 hips) were randomized to receive an Exeter (Stryker Orthopaedics) femoral stem cemented with either Simplex P (standard) or Simplex T (tobramycin-laden) cement. There were 2 years of follow-up, with scheduled radiostereometric (RSA) examinations. Results All stems migrated distally and showed some degree of retroversion. No clinically significant differences in stem subsidence or retroversion we... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611560 Tue, 17 Jan 2012 05:00:00 +0100 5611560 http://www.medworm.com/index.php?rid=5611559&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248164%26dopt%3DAbstract Authors: Yukizawa Y, Inaba Y, Watanabe SI, Yajima S, Kobayashi N, Ishida T, Iwamoto N, Choe H, Saito T Abstract Background and purpose Markers of coagulation and fibrinolysis, such as soluble fibrin (SF), D-dimer, and plasminogen activator inhibitor 1 (PAI-1), have been developed in order to determine thrombotic tendency. We investigated whether these markers could be used to diagnose venous thromboembolism (VTE) in the early phase after primary total hip arthroplasty (THA). Methods This prospective study involved 2 groups: an intermittent pneumatic compression (IPC) group (67 patients who underwent IPC only as prophylaxis for VTE) and a fondaparinux (FPX) group (103 patients who received IPC and FPX postoperatively). Plasma levels of SF and PAI-1 were measured on postoperative da... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611559 Tue, 17 Jan 2012 05:00:00 +0100 5611559 http://www.medworm.com/index.php?rid=5611558&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248165%26dopt%3DAbstract Authors: Palm H, Krasheninnikoff M, Holck K, Lemser T, Foss NB, Jacobsen S, Kehlet H, Gebuhr P Abstract Background and purpose Treatment of hip fracture patients is controversial. We implemented a new operative and supervision algorithm (the Hvidovre algorithm) for surgical treatment of all hip fractures, primarily based on own previously published results. Methods 2,000 consecutive patients over 50 years of age who were admitted and operated on because of a hip fracture were prospectively included. 1,000 of these patients were included after implementation of the algorithm. Demographic parameters, hospital treatment, and reoperations within the first postoperative year were assessed from patient records. Results 931 of 1,000 operative procedures were performed according to the a... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611558 Tue, 17 Jan 2012 05:00:00 +0100 5611558 http://www.medworm.com/index.php?rid=5611557&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248166%26dopt%3DAbstract Authors: Lübbeke A PMID: 22248166 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611557 Tue, 17 Jan 2012 05:00:00 +0100 5611557 http://www.medworm.com/index.php?rid=5611556&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248167%26dopt%3DAbstract Authors: Mosfeldt M, Pedersen OB, Riis T, Worm HO, Mark SV, Jørgensen HL, Duus BR, Lauritzen JB Abstract Background There is a 5- to 8-fold increased risk of mortality during the first 3 months after a hip fracture. Several risk factors are known. We studied the predictive value (for mortality) of routine blood tests taken on admission. Methods 792 hip fracture patients were included prospectively; blood tests were taken on admission. Follow-up data on mortality were obtained from the civil registration system. Patients were divided into 2 groups based on whether they had survived at least 90 days after the hip fracture. To estimate which laboratory tests could be used to predict outcome, we used receiver operation characteristic (ROC) curves. Results 3-month mortality could be ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611556 Tue, 17 Jan 2012 05:00:00 +0100 5611556 http://www.medworm.com/index.php?rid=5611555&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248168%26dopt%3DAbstract Authors: Reigstad A, Mjørud J PMID: 22248168 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611555 Tue, 17 Jan 2012 05:00:00 +0100 5611555 http://www.medworm.com/index.php?rid=5611554&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248169%26dopt%3DAbstract Authors: Virtanen KJ, Malmivaara AO, Remes VM, Paavola MP Abstract Background and purpose Traditionally, clavicle fractures have been treated nonoperatively. However, many recent studies have concentrated on the results of operative treatment. We assessed and compared the outcomes of operative and nonoperative treatment for acute clavicle fractures in adults. Methods We performed a systematic search of the medical literature from 1966 until the end of March 2011. We included randomized controlled trials and controlled clinical trials comparing operative and nonoperative treatment and studies comparing different operative and nonoperative treatments. We required that there should be at least 30 adult patients and a follow-up of at least 6 months in each individual trial. We used th... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611554 Tue, 17 Jan 2012 05:00:00 +0100 5611554 http://www.medworm.com/index.php?rid=5611553&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248170%26dopt%3DAbstract This study provides further evidence that early rat rib callus is not only smooth muscle-like in nature but also contains a notable population of cells that have a distinct myofibroblastic phenotype. The presence of these cells indicates that in vivo contraction of early callus is a mechanism that may occur in fractures so as to facilitate healing, as it does in soft tissue wound repair. PMID: 22248170 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611553 Tue, 17 Jan 2012 05:00:00 +0100 5611553 http://www.medworm.com/index.php?rid=5611552&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248171%26dopt%3DAbstract Authors: Nerhus TK, Heir S, Svege I, Skråmm I, Jervidalo T, Madsen JE, Ekeland A Abstract Background and purpose 10-year survival rates after unicompartmental knee replacement (UKR) have been up to 97% in single-center studies, but they have been as low as 80% in studies from arthroplasty registers. Few studies have evaluated short-term functional outcome and its improvement with time. We determined the time course of functional outcome as evaluated by the knee injury and osteoarthritis outcome score (KOOS) over the first 2 years after Oxford medial UKR. Patients and methods In a prospective multicenter study, we included 99 unselected knees (96 patients, mean age 65 (51-80) years, 57 women) operated with Oxford medial UKR at 3 hospitals in the southeast of Norway between Novembe... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611552 Tue, 17 Jan 2012 05:00:00 +0100 5611552 http://www.medworm.com/index.php?rid=5611551&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248172%26dopt%3DAbstract Authors: Röhrl SM, Nivbrant B, Nilsson KG Abstract Background and purpose Highly crosslinked polyethylene (PE) is in standard use worldwide. Differences in the crosslinking procedure may affect the clinical performance. Experimenatal data from retrieved cups have shown free radicals and excessive wear of annealed highly crosslinked PE. We have previously reported low wear and good clinical performance after 6 years with this implant, and now report on the 10-year results. Patients and methods In 8 patients, we measured wear of annealed highly crosslinked PE prospectively with radiostereometry after 10 years. Activity was assessed by UCLA activity score and a specifically designed activity score. Conventional radiographs were evaluated for osteolysis and clinical outcome by the Ha... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5611551 Tue, 17 Jan 2012 05:00:00 +0100 5611551 http://www.medworm.com/index.php?rid=5556691&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22206445%26dopt%3DAbstract Authors: Hallan G, Espehaug B, Furnes O, Wangen H, Høl PJ, Ellison P, Havelin LI Abstract Background and purpose Despite the fact that there have been some reports on poor performance, titanium femoral stems intended for cemented fixation are still used at some centers in Europe. In this population-based registry study, we examined the results of the most frequently used cemented titanium stem in Norway. Patients and methods 11,876 cases implanted with the cemented Titan stem were identified for the period 1987-2008. Hybrid arthroplasties were excluded, leaving 10,108 cases for this study. Stem survival and the influence of age, sex, stem offset and size, and femoral head size were evaluated using Cox regression analyses. Questionnaires were sent to the hospitals to determine the... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5556691 Thu, 29 Dec 2011 05:00:00 +0100 5556691 http://www.medworm.com/index.php?rid=5556690&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22206446%26dopt%3DAbstract Authors: Benoni AC, Bremander A, Nilsdotter A Abstract Background and purpose Although decreasing with the development of effective pharmacological regimes, joint surgery has improved the function and quality of life of patients with rheumatoid arthritis (RA). Few studies have assessed patient-reported outcomes after RA surgery to the lower extremities. Here we report patient-relevant outcome after RA-related surgery based on the first data from the Swedish National Register of Rheuma Surgery (RAKIR). Patients and methods 258 RA patients (212 women) who had joint surgery performed at the Department of Orthopaedics, Spenshult Hospital between September 2007 and June 2009 were included. Mean age at surgery was 64 (20-86) years. The patients completed the SF-36 and HAQ questionnaires... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5556690 Thu, 29 Dec 2011 05:00:00 +0100 5556690 http://www.medworm.com/index.php?rid=5556689&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22206447%26dopt%3DAbstract Authors: Wilson DA, Richardson G, Hennigar AW, Dunbar MJ Abstract Background and purpose The trabecular metal tibial monoblock component (TM) is a relatively new option available for total knee arthroplasty. We have previously reported a large degree of early migration of the trabecular metal component in a subset of patients. These implants all appeared to stabilize at 2 years. We now present 5-year RSA results of the TM and compare them with those of the NexGen Option Stemmed cemented tibial component (Zimmer, Warsaw IN). Patients and methods 70 patients with osteoarthritis were randomized to receive either the TM implant or the cemented component. RSA examination was done postoperatively and at 6 months, 1 year, 2 years, and 5 years. RSA outcomes were translations, rotations, a... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5556689 Thu, 29 Dec 2011 05:00:00 +0100 5556689 http://www.medworm.com/index.php?rid=5556688&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22206448%26dopt%3DAbstract Authors: Rübenhagen R, Schüttrumpf JP, Stürmer KM, Frosch KH Abstract Background and purpose Little is known about biochemical mediators that correlate with the initiation and progression of knee osteoarthritis (OA). We therefore valuated the roles of cytokines and metalloenzymes in knee OA in relation to OA grading, age, and BMI. Patients and methods A multiplex ELISA-based immunoassay (Luminex technology) was used to measure biochemical mediators in the synovial fluid (SF) of 82 patients undergoing knee surgery. All patients were classified according to age, BMI, and OA grade. 24 patients had no signs of OA (knee reconstruction surgeries). The mediators that were tested for included interleukins (IL-1Ra, IL-6, IL-7, and IL-18), chemokines (CCL2 (MCP-1), CCL3 (MIP-1a), and CXC... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5556688 Thu, 29 Dec 2011 05:00:00 +0100 5556688 http://www.medworm.com/index.php?rid=5556687&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22206449%26dopt%3DAbstract This study included 306 patients with prostate cancer operated for skeletal metastases during 1989-2010. Kaplan-Meier analysis was used to calculate survival. Cox multiple regression analysis was performed to study risk factors, and results were expressed as hazard ratios (HRs). Results The median age at surgery was 72 (49-94) years. The median survival after surgery was 0.5 (0-16) years. The cumulative 1-, 2-, and 3-year survival after surgery was 29% (95% CI: 24-34), 14% (10-18), and 8% (5-11). Age over 70 years (HR 1.4), generalized metastases (HR 2.4), and multiple skeletal metastases (HR 2.3) resulted in an increased risk of death after surgery. Patients with lesions in the humerus (HR 0.6) had a lower death rate. The reoperation rate was 9% (n = 31). The reasons for reoperation were... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5556687 Thu, 29 Dec 2011 05:00:00 +0100 5556687 http://www.medworm.com/index.php?rid=5521257&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22112151%26dopt%3DAbstract We describe the hemiarthroplasty population in Sweden 2005 through 2009. Methods Since 2005, the Swedish Hip Arthroplasty Register has registered hemiarthroplasties on a national basis. We assessed hemiarthroplasty procedures in the Register 2005-2009 regarding patient details, implants, and surgical techniques. Completeness of recordings was calculated compared to the Swedish National Patient Register. Results Completeness increased from 89% to 96% during the study period. 21,346 hemiarthroplasty procedures were assessed. The relative number of patients with femoral neck fracture as diagnosis increased from 91% to 94%; the proportion of men increased from 27% to 30%. The median age increased from 83 to 84 years in men and from 84 to 85 years in women. Patients classified as having evide... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5521257 Wed, 23 Nov 2011 05:00:00 +0100 5521257 http://www.medworm.com/index.php?rid=5521256&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22112152%26dopt%3DAbstract Authors: Lehmann TG, Engesæter IO, Laborie LB, Lie SA, Rosendahl K, Engesæter LB Abstract Background and purpose Pediatric hip diseases account for 9% of all primary hip arthroplasties in the Norwegian Arthroplasty Register. We wanted to validate the diagnosis as reported to the register and to assess the quality of life of these patients after hip replacement. Patients and methods 540 patients accepted to participate in this follow-up study (634 hips). All were less than 40 years of age and had been reported to the Norwegian Arthroplasty Register as having undergone a primary total hip arthroplasty (THA) between 1987 and 2007. The underlying diagnosis, age at diagnosis, and type of treatment given prior to the hip replacement were recorded from the original hospital notes. Res... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5521256 Wed, 23 Nov 2011 05:00:00 +0100 5521256 http://www.medworm.com/index.php?rid=5521255&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22112153%26dopt%3DAbstract Authors: Seo JG, Moon YW, Park SH, Kang HM, Kim SM Abstract Background and purpose Identification of the center of the femoral head in the coronal plane is essential during total knee arthroplasty. We evaluated a new method for localization of the center of the hip, thereby detecting the neutral mechanical axis using inter-femoral head center distances (X) measured from a radiograph. Our proposed method was compared with 3 commonly used methods using landmarks that are estimated to be 2 finger-breaths medial to the anterosuperior iliac spine (method A), 2.5 cm perpendicular to the mid-inguinal point (method I), and 1.5 cm lateral to the femoral artery (method F). Methods 114 patients undergoing total knee arthroplasty were prospectively enrolled in the study. Four landmarks were m... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5521255 Wed, 23 Nov 2011 05:00:00 +0100 5521255 http://www.medworm.com/index.php?rid=5521254&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22112154%26dopt%3DAbstract Authors: Schewelov TV, Ahlborg H, Sanzén L, Besjakov J, Carlsson A Abstract Background Today, dislocated femoral neck fractures are commonly treated with a cemented hip arthroplasty. However, cementing of the femoral component may lead to adverse effects and even death. Uncemented stems may lower these risks and hydroxyapatite (HA) coating may enhance integration, but prosthetic stability and clinical outcome in patients with osteoporotic bone have not been fully explored. We therefore studied fixation and clinical outcome in patients who had had a femoral neck fracture and who had received a fully HA-coated stem prosthesis. Patients and methods 50 patients with a dislocated femoral neck fracture were operated with the fully HA-coated Corail total or hemiarthroplasty. 38 patients... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5521254 Wed, 23 Nov 2011 05:00:00 +0100 5521254 http://www.medworm.com/index.php?rid=5521253&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22112155%26dopt%3DAbstract We report on the establishment, the baseline data, and the results at 1-year follow-up. Methods Primary and revision shoulder stabilization is reported by the surgeon on a 1-page paper form containing the patient's history of shoulder injury, clinical findings, and perioperative findings. The WOSI questionnaire for self-assessment of shoulder function is completed at baseline and at follow-up after 1, 2, and 5 years. To evaluate the completeness of registration, we compared our data with those in the Norwegian Patient Registry (NPR). Results The NPR reported 39 hospitals performing shoulder stabilizations. 20 of these started to report to our register during 2009, and 464 procedures (404 primary, 59 revisions) were included up to December 31, 2009, which represented 54% of the procedures... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5521253 Wed, 23 Nov 2011 05:00:00 +0100 5521253 http://www.medworm.com/index.php?rid=5521252&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22112156%26dopt%3DAbstract Authors: Ullmark G, Sundgren K, Milbrink J, Nilsson O, Sörensen J Abstract Background and purpose One concern regarding resurfacing arthroplasty is the viability of the diminished femoral head and the postoperative risk of collapse, or a femoral neck fracture. (18)F-fluoride positron emission tomography (F-PET) enables us to assess bone viability despite there being a covering metal component. By F-PET studies, we recently showed the absence of metabolism in the remaining part of femoral heads, 1-4 years after surgery in 11 of 46 consecutive cases. We now present the further development of bone metabolism in these 11 cases. Patients and methods 10 patients (11 chips) with previously shown loss of femoral head metabolism were evaluated by radiography and repeated F-PET scans, 3-6.... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5521252 Wed, 23 Nov 2011 05:00:00 +0100 5521252 http://www.medworm.com/index.php?rid=5430535&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066551%26dopt%3DAbstract Authors: Henricson A, Nilsson JK, Carlsson K Abstract Background and purpose There is an ongoing need to review large series of total ankle replacements (TARs) for monitoring of changes in practice and their outcome. 4 national registries, including the Swedish Ankle Register, have previously reported their 5-year results. We now present an extended series with a longer follow-up, and with a 10-year survival analysis. Patients and methods Records of uncemented 3-component TARs were retrospectively reviewed, determining risk factors such as age, sex, and diagnosis. Prosthetic survival rates were calculated with exchange or removal of components as endpoint?excluding incidental exchange of the polyethylene meniscus. Results Of the 780 prostheses implanted since 1993, 168 (22%) had ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430535 Wed, 09 Nov 2011 05:00:00 +0100 5430535 http://www.medworm.com/index.php?rid=5430512&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066552%26dopt%3DAbstract We examined a homogeneous group of patients with primary central chondrosarcoma of bone who were treated according to a uniform surgical protocol at our institution, in order to determine the factors that influence survival and identify potential improvements to our therapeutic algorithm. Patients and methods We performed a retrospective analysis of 115 patients with primary central chondrosarcoma of bone who presented with localized disease and who had a minimum follow-up of 5 years after diagnosis. 68 tumors were localized in the extremities and 47 in the axial skeleton or pelvis. 59 patients had a high-grade (II and III) and 56 a low-grade (I) tumor. 94 patients underwent surgical resection with adequate (wide or radical) margins, while 21 patients had inadequate (marginal or intralesi... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430512 Wed, 09 Nov 2011 05:00:00 +0100 5430512 http://www.medworm.com/index.php?rid=5430511&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066553%26dopt%3DAbstract We present the outcome of the biaxial total wrist prosthesis (no longer available) after 5?8 years of follow-up. Patients and methods40 biaxial wrist prostheses were implanted uncemented in 36 patients with rheumatoid arthritis. 32 wrists were followed clinically and radiographically. 7 prostheses had been revised at median 21 (8?71) months; 1 patient died from an unrelated cause. Mean follow-up of the remaining 32 wrists was 6 (5?8) years. Kaplan-Meier survival analysis was performed with revision defined as failure. ResultsSurvival after 7 years was 81% (95% CI: 64?91). There were 31 complications. 22 wrists showed radiographic loosening. Range of motion improved, except for pronation. The mean DASH score improved and the median postoperative pain score (from 0 to 10) was 0 (0?6) at re... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430511 Wed, 09 Nov 2011 05:00:00 +0100 5430511 http://www.medworm.com/index.php?rid=5430510&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066554%26dopt%3DAbstract Authors: Young S, Lie SA, Hallan G, Zirkle LG, Enges Ter LB, Havelin LI Abstract Background The Surgical Implant Generation Network (SIGN) supplies intramedullary (IM) nails for the treatment of long bone fractures free of charge to hospitals in low- and middle-income countries (LMICs). Most operations are reported to the SIGN Online Surgical Database (SOSD). Follow-up has been reported to be low, however. We wanted to examine the pattern of follow-up and to assess whether infection rates could be trusted. Patients and methods The SOSD contained 36,454 IM nail surgeries in 55 LMICs. We excluded humerus and hip fractures, and fractures without a registered surgical approach. This left 34,361 IM nails for analysis. A generalized additive regression model (gam) was used to explore th... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430510 Wed, 09 Nov 2011 05:00:00 +0100 5430510 http://www.medworm.com/index.php?rid=5430509&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066555%26dopt%3DAbstract Authors: Svensson GL, Lundberg M, Stgaard HC, Wendt GK Abstract Background and purpose Several studies have investigated outcomes after disc surgery. However, the occurrence of kinesiophobia has not been investigated previously in patients after disc herniation surgery. In this cross-sectional study, we investigated kinesiophobia in patients who had been treated surgically for lumbar disc herniation, and we related the results to established outcome measures. Patients and methods 10?34 months after surgery, questionnaires were sent to 97 patients who had undergone standardized open discectomy. Outcome measures included Tampa scale for kinesiophobia (TSK); Oswestry disability index (ODI); European quality of life in 5 dimensions (EQ-5D); visual analog scale (VAS) for leg and back p... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430509 Wed, 09 Nov 2011 05:00:00 +0100 5430509 http://www.medworm.com/index.php?rid=5430508&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066556%26dopt%3DAbstract Authors: Lee JW, Lee S, Lee SH, Yang HS, Im GI, Kim CS, Park JH, Kim BS Abstract Background and purpose Various new delivery systems for recombinant human bone morphogenetic protein-2 (rhBMP-2) have been introduced to improve its efficacy in osteogenesis. Of these, we have previously developed heparin-conjugated PLGA nanospheres (HCPN) as a long-term delivery system for BMP-2. In vitro studies have shown that the BMP-2 long-term delivery system enhances the level of bone formation. However, the long-term effects of BMP-2 on spinal fusion have not been assessed. Therefore, we now tested the hypothesis that the long-term delivery of BMP-2 using HCPN improves spinal fusion compared to short-term delivery in a rabbit fusion model. Methods 24 adult New Zealand White rabbits underwent p... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430508 Wed, 09 Nov 2011 05:00:00 +0100 5430508 http://www.medworm.com/index.php?rid=5430507&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066557%26dopt%3DAbstract Authors: Bj Rgul K, Reigstad A PMID: 22066557 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430507 Wed, 09 Nov 2011 05:00:00 +0100 5430507 http://www.medworm.com/index.php?rid=5430506&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066558%26dopt%3DAbstract Authors: Baker R, Whitehouse M, Kilshaw M, Pabbruwe M, Spencer R, Blom A, Bannister G Abstract Background and purpose We noticed that our instruments were often too hot to touch after preparing the femoral head for resurfacing, and questioned whether the heat generated could exceed temperatures known to cause osteonecrosis. Patients and methods Using an infra-red thermal imaging camera, we measured real-time femoral head temperatures during femoral head reaming in 35 patients undergoing resurfacing hip arthroplasty. 7 patients received an ASR, 8 received a Cormet, and 20 received a Birmingham resurfacing arthroplasty. Results The maximum temperature recorded was 89?C. The temperature exceeded 47?C in 28 patients and 70?C in 11. The mean duration of most stages of head preparation... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430506 Wed, 09 Nov 2011 05:00:00 +0100 5430506 http://www.medworm.com/index.php?rid=5430505&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066559%26dopt%3DAbstract Authors: Meijerink HJ, Verdonschot N, van Loon CJ, Hannink G, de Waalmalefijt MC Abstract Background and purpose To try to improve the outcome of our TKAs, we started to use the CKS prosthesis. However, in a retrospective analysis this design tended to give worse results. We therefore conducted a randomized, controlled trial comparing this CKS prosthesis and our standard PFC prosthesis. Because many randomized studies between different TKA concepts generally fail to show superiority of a particular design, we hypothesized that these seemingly similar designs would not lead to any difference in clinical outcome. Patients and methods 82 patients (90 knees) were randomly allocated to one or other prosthesis, and 39 CKS prostheses and 38 PFC prostheses could be followed for mean 5.6 y... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430505 Wed, 09 Nov 2011 05:00:00 +0100 5430505 http://www.medworm.com/index.php?rid=5430504&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066560%26dopt%3DAbstract Authors: Husted H, Lunn TH, Troelsen A, Gaarn-Larsen L, Kristensen BB, Kehlet H Abstract Background and purpose Length of stay (LOS) following total hip and knee arthroplasty (THA and TKA) has been reduced to about 3 days in fast-track setups with functional discharge criteria. Earlier studies have identified patient characteristics predicting LOS, but little is known about specific reasons for being hospitalized following fast-track THA and TKA. Patients and methods To determine clinical and logistical factors that keep patients in hospital for the first postoperative 24?72 hours, we performed a cohort study of consecutive, unselected patients undergoing unilateral primary THA (n = 98) or TKA (n = 109). Median length of stay was 2 days. Patients were operated with spinal anesthes... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430504 Wed, 09 Nov 2011 05:00:00 +0100 5430504 http://www.medworm.com/index.php?rid=5430503&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066561%26dopt%3DAbstract Authors: Wilson LJ, Richards CJ, Irvine D, Tillie A, Crawford RW Abstract Background and purpose Removal of distal cement at femoral implant revision is technically challenging and is associated with complications such as cortical perforations. A technique that can reduce the risks and operating time is to make a small cortical window in the distal femur for enhanced access. We wanted to determine whether the use of long, bridging, cemented femoral stems is necessary to reduce the risk of postoperative periprosthetic fractures after using an anterior cortical bone window. Methods 66 fresh pig femurs underwent mechanical testing. Steel rods were implanted at 3 locations: (1) at the distal window edge, (2) 15 mm proximally to the cortical window edge, and (3) 15 mm distally. 54 femu... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430503 Wed, 09 Nov 2011 05:00:00 +0100 5430503 http://www.medworm.com/index.php?rid=5430502&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066562%26dopt%3DAbstract Authors: Dale HV, Skr Mm I, L Wer HL, Eriksen HM, Espehaug B, Furnes O, Skjeldestad FE, Havelin LI, Enges Ter LB Abstract Background and purpose The aim of the present study was to assess incidence of and risk factors for infection after hip arthroplasty in data from 3 national health registries. We investigated differences in risk patterns between surgical site infection (SSI) and revision due to infection after primary total hip arthroplasty (THA) and hemiarthroplasty (HA). Materials and methods This observational study was based on prospective data from 2005?2009 on primary THAs and HAs from the Norwegian Arthroplasty Register (NAR), the Norwegian Hip Fracture Register (NHFR), and the Norwegian Surveillance System for Healthcare?Associated Infections (NOIS). The Norwegian Patie... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430502 Wed, 09 Nov 2011 05:00:00 +0100 5430502 http://www.medworm.com/index.php?rid=5430501&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066563%26dopt%3DAbstract Authors: Boesenach B, van der Heide HJ, Nelissen RG Abstract BackgroundA number of excellent results with the cementless titanium femoral component of the Mallory Head Total Hip Replacement have been published. Unfortunately, these excellent results have been counteracted by the poor performance of the cementless titanium acetabular components. In 1994, the HexLoc acetabular component was replaced with a second-generation design, the RingLoc. We hypothesized that the new generation would have improved the results. Methods We retrospectively studied 111 consecutive patients (150 hips) younger than 55 years. Median follow-up time was 14 (6?18) years for the HexLoc and 10 (1?14) years for the RingLoc. 7 patients were lost to follow-up and 7 patients died. The 10-year survival rate, r... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430501 Wed, 09 Nov 2011 05:00:00 +0100 5430501 http://www.medworm.com/index.php?rid=5430500&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066564%26dopt%3DAbstract Authors: Hrn A, Olai A, Rutberg H, Nilsen P, Tropp H Abstract Background and purpose Our knowledge of complications and adverse events in spinal surgery is limited, especially concerning incidence and consequences. We therefore investigated adverse events in spine surgery in Sweden by comparing patient claims data from the County Councils' Mutual Insurance Company register with data from the National Swedish Spine Register (Swespine). Methods We analyzed patient claims (n = 182) to the insurance company after spine surgery performed between 2003 and 2005. The medical records of the patients filing these claims were reviewed and compared with Swespine data for the same period. Results Two-thirds (119/182, 65%) of patients who claimed economic compensation from the insurance compan... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5430500 Wed, 09 Nov 2011 05:00:00 +0100 5430500 http://www.medworm.com/index.php?rid=5364711&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22026413%26dopt%3DAbstract Authors: Dobrydnjov I, Anderberg C, Olsson C, Shapurova O, Angel K, Bergman S Abstract Background and purpose Ropivacaine infusion following high-volume local infiltration analgesia has been shown to be effective after total knee arthroplasty, but the optimum site of administration of ropivacaine has not been evaluated. We compared the effects of intraarticular and extraarticular adminstration of the local anesthetic for postoperative supplementation of high-volume local infiltration analgesia. Patients and methods In this double-blind study, 36 rheumatic patients aged 51-78 years with physical status ASA 2-3 who were scheduled for total knee arthroplasty were randomized into 2 groups. All patients received wound infiltration at the end of surgery with 300 mg ropivacaine, 30 mg ke... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5364711 Tue, 25 Oct 2011 04:00:00 +0100 5364711 http://www.medworm.com/index.php?rid=5364716&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21999621%26dopt%3DAbstract Authors: Lunsjö K, Bengtsson M, Nordqvist A, Abu-Zidan FM Abstract Background Although arthroscopic subacromial decompression (ASD) is a common procedure for treatment of shoulder impingement, few long term results have been published. In this prospective study, we determined whether the high degree of patient satisfaction at 6 months postoperatively reported by us earlier remained at the 6-year follow-up. Patients and methods We originally reported high patient satisfaction 6 months after ASD for shoulder impingement in 50 prospectively studied patients using the Disability of the Arm Shoulder and Hand questionnaire (DASH) and the Visual Analog Scale (VAS). Patients with associated shoulder disorders were excluded. The surgeons were experienced shoulder arthroscopists. 6 years a... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5364716 Mon, 17 Oct 2011 04:00:00 +0100 5364716 http://www.medworm.com/index.php?rid=5364715&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21999622%26dopt%3DAbstract Authors: Barg A, Henninger HB, Knupp M, Hintermann B Abstract Background and purpose Total ankle replacement is an established surgical procedure in patients with end-stage ankle osteoarthritis. We analyzed complications and medium-term results in patients with simultaneous bilateral total ankle replacement. Patients and methods 10 women and 16 men, mean age 60 (SD 13) years, were followed for a median of 5 (2-10) years. Results There were no intraoperative or perioperative complications, with the exception of 1 patient with prolonged wound healing. Major revision surgery was necessary in 6 of the 52 ankles, including 4 revisions of prosthetic components. The average pain score decreased from 6.9 (4-10) to 1.8 (0-4) points. The American Orthopaedic Foot and Ankle Society hindfoo... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5364715 Mon, 17 Oct 2011 04:00:00 +0100 5364715 http://www.medworm.com/index.php?rid=5364714&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21999623%26dopt%3DAbstract Authors: McConnell JS, Shewale S, Munro NA, Shah K, Deakin AH, Kinninmonth AW Abstract Background and purpose Previous studies have shown that either fibrin spray or tranexamic acid can reduce blood loss at total hip replacement, but the 2 treatments have not been directly compared. We therefore conducted a randomized, controlled trial. Patients and methods In this randomized controlled trial we compared the effect of tranexamic acid and fibrin spray on blood loss in cemented total hip arthroplasty. 66 patients were randomized to 1 of 3 parallel groups receiving (1) a 10 mg/kg bolus of tranexamic acid prior to surgery, (2) 10 mL of fibrin spray during surgery, or (3) neither. All participants except the surgeon were blinded as to treatment group until data analysis was complete. B... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5364714 Mon, 17 Oct 2011 04:00:00 +0100 5364714 http://www.medworm.com/index.php?rid=5364713&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21999624%26dopt%3DAbstract Authors: Lindalen E, Havelin LI, Nordsletten L, Dybvik E, Fenstad AM, Hallan G, Furnes O, Høvik O, Röhrl SM Abstract Background and purpose Reverse hybrid hip replacement uses a cemented all-polyethylene cup and an uncemented stem. Despite increasing use of this method in Scandinavia, there has been very little documentation of results. We have therefore analyzed the results from the Norwegian Arthroplasty Register (NAR), with up to 10 years of follow-up. Patients and methods The NAR has been collecting data on total hip replacement (THR) since 1987. Reverse hybrid hip replacements were used mainly from 2000. We extracted data on reverse hybrid THR from this year onward until December 31, 2009, and compared the results with those from cemented implants over the same period. Spec... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5364713 Mon, 17 Oct 2011 04:00:00 +0100 5364713 http://www.medworm.com/index.php?rid=5364712&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21999625%26dopt%3DAbstract Authors: Meuffels DE, Potters JW, Koning AH, Brown Jr CH, Verhaar JA, Reijman M Abstract Background and purpose Non-anatomic bone tunnel placement is the most common cause of a failed ACL reconstruction. Accurate and reproducible methods to visualize and document bone tunnel placement are therefore important. We evaluated the reliability of standard radiographs, CT scans, and a 3-dimensional (3D) virtual reality (VR) approach in visualizing and measuring ACL reconstruction bone tunnel placement. Methods 50 consecutive patients who underwent single-bundle ACL reconstructions were evaluated postoperatively by standard radiographs, CT scans, and 3D VR images. Tibial and femoral tunnel positions were measured by 2 observers using the traditional methods of Amis, Aglietti, Hoser, Stäu... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5364712 Mon, 17 Oct 2011 04:00:00 +0100 5364712 http://www.medworm.com/index.php?rid=5322035&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21992083%26dopt%3DAbstract Authors: Aspenberg P PMID: 21992083 [PubMed - in process] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5322035 Sat, 01 Oct 2011 04:00:00 +0100 5322035 http://www.medworm.com/index.php?rid=5322034&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21992084%26dopt%3DAbstract Authors: Mäkelä KT, Eskelinen A, Pulkkinen P, Paavolainen P, Remes V Abstract Background and purpose In a previous study based on the Finnish Arthroplasty Register, the survival of cementless stems was better than that of cemented stems in younger patients. However, the survival of cementless cups was poor due to osteolysis. In the present study, we analyzed population-based survival rates of the cemented and cementless total hip replacements in patients under the age of 55 years with primary osteoarthritis in Finland. Patients and methods 3,668 implants fulfilled our inclusion criteria. The previous data included years 1980-2001, whereas the current study includes years 1987-2006. The implants were classified in 3 groups: (1) implants with a cementless, straight, proximally cir... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5322034 Sat, 01 Oct 2011 04:00:00 +0100 5322034 http://www.medworm.com/index.php?rid=5322033&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21992085%26dopt%3DAbstract Authors: Engesæter LB, Dale H, Schrama JC, Hallan G, Lie SA Abstract Background and purpose Controversies still exist regarding the best surgical procedure in the treatment of periprosthetic infection after total hip arthroplasty (THA). Based on data in the Norwegian Arthroplasty Register (NAR), we have compared the risk of re-revision after 4 different surgical procedures: 2-stage with exchange of the whole prosthesis, 1-stage with exchange of the whole prosthesis, major partial 1-stage with exchange of stem or cup, and minor partial 1-stage with exchange of femoral head and/or acetabular liner. Methods Between 1987 and 2009, 124,759 primary THAs were reported to the NAR, of which 906 (0.7%) were revised due to infection. Included in this study were the 784 revisions that had be... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5322033 Sat, 01 Oct 2011 04:00:00 +0100 5322033 http://www.medworm.com/index.php?rid=5322032&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21992086%26dopt%3DAbstract Authors: Swierstra BA, Vervest AM, Walenkamp GH, Schreurs BW, Spierings PT, Heyligers IC, van Susante JL, Ettema HB, Jansen MJ, Hennis PJ, de Vries J, Muller-Ploeger SB, Pols MA PMID: 21992086 [PubMed - in process] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5322032 Sat, 01 Oct 2011 04:00:00 +0100 5322032 http://www.medworm.com/index.php?rid=5322031&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21992087%26dopt%3DAbstract We describe the outcome and compare the rates of iatrogenic injuries to the ulnar nerve in a consecutive series of displaced supracondylar humeral fractures in children treated with either crossed pinning or antegrade nailing. Methods Medical charts of all children sustaining this fracture treated at our department between 1994 and 2009 were retrospectively reviewed regarding the mode of treatment, demographic data including age and sex, the time until implant removal, the outcome, and the rate of ulnar nerve injuries. Results 503 children (55% boys) with an average age of 6.5 years sustained a type-II, type-III, or type-IV supracondylar fracture. Of those, 440 children were included in the study. Antegrade nailing was performed in 264 (60%) of the children, and the others were treated w... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5322031 Sat, 01 Oct 2011 04:00:00 +0100 5322031 http://www.medworm.com/index.php?rid=5207239&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895497%26dopt%3DAbstract Authors: Vestermark MT, Hauge EM, Soballe K, Bechtold JE, Jakobsen T, Baas J Abstract Background and purpose Allografts are often used during revision hip replacement surgery for stabilization of the implant. Resorption of the allograft may exceed new bone formation, and instability of the prosthesis can develop. We investigated whether strontium could regulate the imbalance of fast resorption of allograft and slower formation of new bone, because it is both an anabolic and an anticatabolic agent. Method Strontium was added to the implant interface environment by doping a hydroxyapatite bone graft extender. 10 dogs each received 2 experimental titanium implants. The implants were inserted within a 2.7-mm concentric gap in cancellous bone. The gap was filled with 50% (v/v) allograft... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207239 Tue, 06 Sep 2011 04:00:00 +0100 5207239 http://www.medworm.com/index.php?rid=5207238&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895498%26dopt%3DAbstract Authors: de Vries LM, Sturkenboom MC, Verhaar JA, Kingma JH, Stricker BH Abstract Background and purpose It has been suggested that a higher procedure volume is associated with less complications after hip arthroplasty. In order to investigate the incidence of serious negative outcomes and a possible association with procedure volume, we performed a retrospective nationwide cohort study on total hip replacements in all Dutch hospitals. Methods All total hip replacements (n = 50,080) that were identified as primary intervention in all general and university medical centers between January 1, 2002 and October 1, 2004 were included. Primary endpoints of follow-up were mortality and complications during admission, and re-admission within 3 months due to complications. Variables that we... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207238 Tue, 06 Sep 2011 04:00:00 +0100 5207238 http://www.medworm.com/index.php?rid=5207237&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895499%26dopt%3DAbstract Authors: Munk S, Odgaard A, Madsen F, Dalsgaard J, Jorn LP, Langhoff O, Jepsen CF, Hansen TB Abstract Background and purpose There is disagreement in the literature about the importance of patellofemoral joint degeneration and knee pain for the outcome of unicompartmental knee arthroplasty (UKA). We therefore investigated the importance of selected predictors including patellofemoral joint degeneration and the location of preoperative knee pain for the early outcome of UKA. Patients and methods The study group comprised 260 consecutive patients from 5 hospitals who underwent Oxford UKA for anteromedial osteoarthritis. Data were collected at baseline and included pain location, radiologically observed degeneration of the patellofemoral joint including subluxation of the patella, int... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207237 Tue, 06 Sep 2011 04:00:00 +0100 5207237 http://www.medworm.com/index.php?rid=5207236&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895500%26dopt%3DAbstract Authors: Malviya A, Martin K, Harper I, Muller SD, Emmerson KP, Partington PF, Reed MR Abstract Background and purpose Multimodal techniques can aid early rehabilitation and discharge of patients following primary joint replacement. We hypothesized that this not only reduces the economic burden of joint replacement by reducing length of stay, but also helps in reduction of early complications. Patients and methods We evaluated 4,500 consecutive unselected total hip replacements and total knee replacements regarding length of hospital stay, mortality, and perioperative complications. The first 3,000 underwent a traditional protocol while the other 1,500 underwent an enhanced recovery protocol involving behavioral, pharmacological, and procedural modifications. Results There was a re... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207236 Tue, 06 Sep 2011 04:00:00 +0100 5207236 http://www.medworm.com/index.php?rid=5207235&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895501%26dopt%3DAbstract Authors: Miles JE, Wenck A, Fricker C, Svalastoga EL Abstract Background and purpose The presence of bone marrow edema in patients with osteoarthritis is associated with pain and disease progression. Management of bone edema with the synthetic prostacyclin iloprost may be complicated by side effects. Calcium dobesilate, a treatment for chronic venous disease, shares some pharmacological actions with iloprost but appears to be better tolerated. Anecdotal reports have suggested that calcium dobesilate may be useful for medical management of osteoarthritis, possibly by reducing bone marrow edema, and this study was performed to investigate possible benefits of treatment. Methods The effects of a 6-week period of oral calcium dobesilate administration on tibial intramedullary pressure ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207235 Tue, 06 Sep 2011 04:00:00 +0100 5207235 http://www.medworm.com/index.php?rid=5207234&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895502%26dopt%3DAbstract Authors: Mattyasovszky SG, Burkhart KJ, Ahlers C, Proschek D, Dietz SO, Becker I, Müller-Haberstock S, Müller LP, Rommens PM Abstract Background and purpose The diagnosis and treatment of isolated greater tuberosity fractures of the proximal humerus is not clear-cut. We retrospectively assessed the clinical and radiographic outcome of isolated greater tuberosity fractures. Patients and methods 30 patients (mean age 58 (26-85) years, 19 women) with 30 closed isolated greater tuberosity fractures were reassessed after an average follow-up time of 3 years with DASH score and Constant score. Radiographic outcome was assessed on standard plain radiographs. Results 14 of 17 patients with undisplaced or slightly displaced fractures (≤ 5 mm) were treated nonoperatively and had good cli... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207234 Tue, 06 Sep 2011 04:00:00 +0100 5207234 http://www.medworm.com/index.php?rid=5207233&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895503%26dopt%3DAbstract Authors: Cheng T, Zhang G, Zhang X Abstract Background and purpose The choice of either all-polyethylene (AP) tibial components or metal-backed (MB) tibial components in total knee arthroplasty (TKA) remains controversial. We therefore performed a meta-analysis and systematic review of randomized controlled trials that have evaluated MB and AP tibial components in primary TKA. Methods The search strategy included a computerized literature search (Medline, EMBASE, Scopus, and the Cochrane Central Register of Controlled Trials) and a manual search of major orthopedic journals. A meta-analysis and systematic review of randomized or quasi-randomized trials that compared the performance of tibial components in primary TKA was performed using a fixed or random effects model. We assessed ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207233 Tue, 06 Sep 2011 04:00:00 +0100 5207233 http://www.medworm.com/index.php?rid=5207232&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895504%26dopt%3DAbstract Authors: Kadar T, Hallan G, Aamodt A, Indrekvam K, Badawy M, Havelin LI, Stokke T, Haugan K, Espehaug B, Furnes O Abstract Background and purpose We performed a randomized study to determine the migration patterns of the Spectron EF femoral stem and to compare them with those of the Charnley stem, which is regarded by many as the gold standard for comparison of implants due to its extensive documentation. Patients and methods 150 patients with a mean age of 70 years were randomized, single-blinded, to receive either a cemented Charnley flanged 40 monoblock, stainless steel, vaquasheen surface femoral stem with a 22.2-mm head (n = 30) or a cemented Spectron EF modular, matte, straight, collared, cobalt-chrome femoral stem with a 28-mm femoral head and a roughened proximal third of t... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207232 Tue, 06 Sep 2011 04:00:00 +0100 5207232 http://www.medworm.com/index.php?rid=5207231&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895505%26dopt%3DAbstract Authors: Landgren M, Jerrhag D, Tägil M, Kopylov P, Geijer M, Abramo A Abstract Background and purpose We have previously shown in a randomized study that in the first year after treatment, open reduction and internal fixation resulted in better grip strength and forearm rotation than closed reduction and bridging external fixation. In the present study, we investigated whether this difference persists over time. Patients and methods The 50 patients included in the original study (mean age 53 years, 36 women) were sent a QuickDASH questionnaire and an invitation to a radiographic and clinical examination after a mean of 5 (3-7) years. Results All 50 patients returned the QuickDASH questionnaire and 45 participated in the clinical and radiographic examination. In the internal fixat... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207231 Tue, 06 Sep 2011 04:00:00 +0100 5207231 http://www.medworm.com/index.php?rid=5207230&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895506%26dopt%3DAbstract Authors: Damborg F, Engell V, Nielsen J, Kyvik KO, Andersen MO, Thomsen K Abstract Background and purpose The genetic/environmental etiology of Scheuermann's disease is unclear. We estimated the heritability of the disease using an etiological model adjusted for sex and time of diagnosis, and examined whether the prevalence of Scheuermann's disease was constant over time. Methods 46,418 twins were sent a questionnaire about health and disease. Of these, 75% returned the questionnaire and 97% answered the question "Have you been diagnosed as having Scheuermann's disease by a doctor?" Results Responders included 11,436 complete pairs of twins. Data were analysed using classical twin modeling methods. Tetrachoric correlations were used to decide which etiological model to fit. The bes... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207230 Tue, 06 Sep 2011 04:00:00 +0100 5207230 http://www.medworm.com/index.php?rid=5207229&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895507%26dopt%3DAbstract Authors: Hägglund G, Wagner P Abstract Background and purpose Spasticity and muscle contracture are two common manifestations of cerebral palsy (CP). A spastic muscle may inhibit growth in length of the muscle, but the importance of this relationship is not known. In 1994, a register and a healthcare program for children with CP in southern Sweden were initiated. The child's muscle tone according to the Ashworth scale and the ankle range of motion (ROM) is measured annually during the entire growth period. We have used these data to analyze the relationship between spasticity and ROM of the gastrosoleus muscle. Patients and methods All measurements in the total population of children with CP aged 0-18 years during the period January 1995 through June 2008 were analyzed. The study ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207229 Tue, 06 Sep 2011 04:00:00 +0100 5207229 http://www.medworm.com/index.php?rid=5207228&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895508%26dopt%3DAbstract Authors: Gillam MH, Salter A, Ryan P, Graves SE Abstract Purpose Here we describe some available statistical models and illustrate their use for analysis of arthroplasty registry data in the presence of the competing risk of death, when the influence of covariates on the revision rate may be different to the influence on the probability (that is, risk) of the occurrence of revision. Patients and methods Records of 12,525 patients aged 75-84 years who had received hemiarthroplasty for fractured neck of femur were obtained from the Australian Orthopaedic Association National Joint Replacement Registry. The covariates whose effects we investigated were: age, sex, type of prosthesis, and type of fixation (cementless or cemented). Extensions of competing risk regression models were impl... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207228 Tue, 06 Sep 2011 04:00:00 +0100 5207228 http://www.medworm.com/index.php?rid=5207241&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21883049%26dopt%3DAbstract Authors: Chiang ER, Su YP, Chen TH, Chiu FY, Chen WM Abstract Introduction The result of treatment of infections involving antibiotic-resistant organisms in total knee arthroplasty (TKA) is often poor. We evaluated the efficacy of 2-stage revision in TKAs infected with resistant organisms and compared the clinical outcomes with articulating and conventional static spacers, in terms of both infection control and function. Methods In a prospective manner, from June 2003 to January 2007 selected patients with a TKA infected with resistant organisms were enrolled and treated with 2-stage re-implantation. The 45 patients were divided into 2 groups: group A (23 patients) implanted with the articulating spacers and group S (22 patients) implanted with static spacers. All patients followed... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207241 Mon, 01 Aug 2011 04:00:00 +0100 5207241 http://www.medworm.com/index.php?rid=5207240&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21883050%26dopt%3DAbstract We examined the epidemiology of adult distal radius fractures in Iceland in 2004 and compared it with an Icelandic study from 1985 and other studies. Methods A retrospective study of the epidemiology, classification, and treatment of distal radius fractures in Reykjavik residents aged 16 and older in 2004 was conducted by analysis of medical records and re-evaluation of all radiographic examinations. Results The 228 fractures included in our material yielded an overall annual incidence of 17/10(4) in men and 37/10(4) in women. Age-specific incidence rose steadily with age in both sexes. One third of the fractures were intraarticular, and working-age men accounted for a large proportion of them. 95% of fractures were treated nonoperatively. Interpretation The annual incidence of distal radi... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5207240 Mon, 01 Aug 2011 04:00:00 +0100 5207240 http://www.medworm.com/index.php?rid=5029567&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21751858%26dopt%3DAbstract Authors: Lazarinis S, K Rrholm J, Hailer NP Background and purpose Hydroxyapatite (HA) is widely used as a coating for uncemented total hip arthroplasty components. This has been suggested to improve implant ingrowth and long-term stability. However, the evidence behind the use of HA coating on femoral stems is ambiguous. We investigated survival of an uncemented, tapered titanium femoral stem that was available either with or without HA coating (Bi-Metric). Patients and methods The stem had been used in 4,772 total hip arthroplasties (THAs) in 4,169 patients registered in the Swedish Hip Arthroplasty Register between 1992 and 2009. 59% of the stems investigated were coated with HA and 41% were uncoated. Kaplan-Meier survival analysis and a Cox regression model with adjustment for age,... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5029567 Tue, 12 Jul 2011 23:00:00 +0100 5029567 http://www.medworm.com/index.php?rid=5029566&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21751859%26dopt%3DAbstract We describe 4 cases of tendon transfers for correction of foot deformities, which were performed by Harvey Cushing in 1898. PMID: 21751859 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5029566 Tue, 12 Jul 2011 23:00:00 +0100 5029566 http://www.medworm.com/index.php?rid=5029565&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21751860%26dopt%3DAbstract Authors: Gould VC, Wylde V, Smith AJ, Blom AW Background and purpose Deep vein thrombosis is common after total joint replacement. It is frequently asymptomatic, and it is unclear whether this leads to longer-term problems such as post-thrombotic syndrome and leg ulceration. We investigated whether the postoperative prevalence of ulceration in patients who had undergone primary total hip replacement (THR) or total knee replacement (TKR) was higher than that found in a control group who had not undergone total joint replacement. Methods The study group consisted of patients who had undergone THR or TKR at one orthopedic center 12?16 years previously without routine chemothromboprophylaxis, and who had not undergone revision surgery. The control group was recruited via primary care. All ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5029565 Tue, 12 Jul 2011 23:00:00 +0100 5029565 http://www.medworm.com/index.php?rid=5029564&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21751861%26dopt%3DAbstract Authors: Andersen L, Otte KS, Husted H, Gaarn-Larsen L, Kristensen B, Kehlet H Background and purpose High-volume infiltration analgesia may be effective in postoperative pain management after hip arthroplasty but methodological problems prevent exact interpretation of previous studies. Methods In a randomized, double-blind placebo-controlled trial in 12 patients undergoing bilateral total hip arthroplasty (THA) in a fast-track setting, saline or high-volume (170 mL) ropivacaine (0.2%) with epinephrine (1:100,000) was administered to the wound intraoperatively along with supplementary postoperative injections via an intraarticular epidural catheter. Oral analgesia was instituted preoperatively with a multimodal regimen (gabapentin, celecoxib, and acetaminophen). Pain was assessed repea... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=5029564 Tue, 12 Jul 2011 23:00:00 +0100 5029564 http://www.medworm.com/index.php?rid=4984848&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21689068%26dopt%3DAbstract Authors: Cummins F, Reilly PO, Flannery O, Kelly D, Kenny P Background and purpose The two most common complications of femoral impaction bone grafting are femoral fracture and massive implant subsidence. We investigated fracture forces and implant subsidence rates in embalmed human femurs undergoing impaction grafting. The study consisted of two arms, the first examining the force at which femoral fracture occurs in the embalmed human femur, and the second examining whether significant graft implant/subsidence occurs following impaction at a set force at two different impaction frequencies. Methods Using a standardized impaction grafting technique with modifications, an initial group of 17 femurs underwent complete destructive impaction testing, allowing sequentially increased, contro... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4984848 Mon, 20 Jun 2011 23:00:00 +0100 4984848 http://www.medworm.com/index.php?rid=4984847&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21689069%26dopt%3DAbstract Authors: Harding AK, W-Dahl A, Geijer M, Toksvig-Larsen S, Tägil M Background Bisphosphonates increase the callus size and strength in animal fracture studies. In a human non-randomized pilot study of high tibial osteotomies in knee osteoarthritis, using the hemicallotasis (HCO) technique, bisphosphonates shortened the healing time by 12 days. In the present randomized study, we wanted to determine whether a single infusion of zoledronic acid reduces the time to clinical osteotomy healing. Results from the same trial, showing improved pin fixation with zoledronate, have been published separately. Methods 46 consecutive patients (aged 35-65 years) were operated. At 4 weeks postoperatively, the patients were randomized to an intravenous infusion of either zoledronic acid or sodium chlor... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4984847 Mon, 20 Jun 2011 23:00:00 +0100 4984847 http://www.medworm.com/index.php?rid=4930290&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21668387%26dopt%3DAbstract We present medium-term DXA results from a randomized study comparing a customized and an anatomical femoral stem. Methods 100 hips were randomized to receive either the anatomical ABG-I stem or the Unique customized femoral stem, both uncemented. DXA measurements were conducted postoperatively and after 3, 6, 12, 24, 36, and 60 months, and BMD was computed for each of the 7 Gruen zones in the proximal femur. Results Results from 87 patients were available for analysis. 78 completed the 5-year follow-up: 35 patients in the ABG group and 43 patients in the Unique group. In both groups, we found the greatest degree of bone loss in the proximal Gruen zones. In zone 1, there was 15% reduction in BMD in the ABG-I group and 14% reduction in the Unique group. In zone 7, the reduction was 28% in th... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930290 Mon, 13 Jun 2011 23:00:00 +0100 4930290 http://www.medworm.com/index.php?rid=4930289&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21671714%26dopt%3DAbstract Authors: Choe H, Inaba Y, Kobayashi N, Ike H, Aoki C, Shizukuishi K, Iwamoto N, Yukizawa Y, Ishida T, Inoue T, Saito T Background and purpose The accurate diagnosis of periprosthetic infection requires assessment of intraoperative tissues. These must be sampled from the appropriate sites. We used (18)F-fluoride positron emission tomography (PET) to identify sites of inflammation in order to improve the sensitivity of histopathology, microbiological culture, and real-time PCR in total hip arthroplasty (THA) patients. Patients and methods 23 THA patients (23 hips) scheduled for revision surgery (the revision group) and 17 uninfected THA patients (23 hips; control group) were enrolled. Uptake was classified into major, minor, and no uptake. To evaluate the association between the (18)F-fl... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930289 Mon, 13 Jun 2011 23:00:00 +0100 4930289 http://www.medworm.com/index.php?rid=4930308&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657968%26dopt%3DAbstract Conclusion CRP is a predictable and responsive serum parameter in postoperative monitoring of inflammatory responses in patients undergoing spine surgery, whereas WBC kinetics is unspecific. We suggest that CRP could be measured on the day before surgery, on day 2 or 3 after surgery, and also between days 4 and 6, to aid in early detection of infectious complications. PMID: 21657968 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930308 Thu, 09 Jun 2011 23:00:00 +0100 4930308 http://www.medworm.com/index.php?rid=4930307&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657969%26dopt%3DAbstract Authors: Pöyhiä T, Lamminen A, Peltonen J, Willamo P, Nietosvaara Y Background Many children with permanent brachial plexus birth injury (BPBI) develop shoulder problems, with subsequent joint deformity without treatment. We assessed the indications and outcome of shoulder operations for BPBI. Patients and methods 31 BPBI patients who had undergone a shoulder operation in our hospital between March 2002 and December 2005 were included in the study. Relocation of the humeral head had been performed in 13 patients, external rotation osteotomy of the humerus in 5 patients, subscapular tendon lengthening in 5 patients, and teres major transposition in 8 patients. Subjective results were registered. Shoulder range of motion was measured, and function assessed according to the Mallet scale... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930307 Thu, 09 Jun 2011 23:00:00 +0100 4930307 http://www.medworm.com/index.php?rid=4930306&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657970%26dopt%3DAbstract Authors: Brorson S, Frich LH, Winther A, Hróbjartsson A Background and purpose There is considerable uncertainty about the optimal treatment of displaced 4-part fractures of the proximal humerus. Within the last decade, locking plate technology has been considered a breakthrough in the treatment of these complex injuries. Methods We systematically identified and reviewed clinical studies on the benefits and harms after osteosynthesis with locking plates in displaced 4-part fractures. Results We included 14 studies with 374 four-part fractures. There were 10 case series, 3 retrospective observational comparative studies, 1 prospective observational comparative study, and no randomized trials. Small studies with a high risk of bias precluded reliable estimates of functional outcome. Hig... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930306 Thu, 09 Jun 2011 23:00:00 +0100 4930306 http://www.medworm.com/index.php?rid=4930305&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657971%26dopt%3DAbstract We report on the total wrist replacements and their revision rates over a 16-year period. Material and methods 189 patients with 189 primary wrist replacements (90 Biax prostheses (80 of which were cementless), 23 cementless Elos prostheses, and 76 cementless Gibbon prostheses), operated during the period 1994-2009 were identified in the Norwegian Arthroplasty Register. Prosthesis survival was analyzed using Cox regression analyses. The 3 implant designs were compared and time trends were analyzed. Results The 5-year survival was 78% (95% CI: 70-85) and the 10-year survival was 71% (CI: 59-80). Prosthesis survival was 85% (CI: 78-93) at 5 years for the Biax prosthesis, 77% (CI: 30-90) at 4 years for the Gibbon prosthesis, and 57% (CI: 33-81) at 5 years for the Elos prosthesis. There was no... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930305 Thu, 09 Jun 2011 23:00:00 +0100 4930305 http://www.medworm.com/index.php?rid=4930299&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657972%26dopt%3DAbstract Discussion persists as to whether obesity negatively influences the outcome of hip arthroplasty. We performed a meta-analysis with the primary research question of whether obesity has a negative effect on short- and long-term outcome of total hip arthroplasty. Methods We searched the literature and included studies comparing the outcome of hip arthroplasty in different weight groups. The methodology of the studies included was scored according to the Cochrane guidelines. We extracted and pooled the data. For continuous data, we calculated a weighted mean difference and for dichotomous variables we calculated a weighted odds ratio (OR). Heterogeneity was calculated using I(2) statistics. Results 15 studies were eligible for data extraction. In obese patients, dislocation of the hip (OR = 0.... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930299 Thu, 09 Jun 2011 23:00:00 +0100 4930299 http://www.medworm.com/index.php?rid=4930294&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657973%26dopt%3DAbstract This article gives a brief overview of the major milestones in skeletal evolution. Some molecular machineries involving members of core genetic networks and their interactions are described in the context of both old theories and modern genetic approaches. PMID: 21657973 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930294 Thu, 09 Jun 2011 23:00:00 +0100 4930294 http://www.medworm.com/index.php?rid=4930293&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657974%26dopt%3DAbstract Authors: Crnalic S, Hildingsson C, Wikström P, Bergh A, Löfvenberg R, Widmark A Background and purpose The criteria for selecting patients who may benefit from surgery of spinal cord compression in metastatic prostate cancer are poorly defined. We therefore studied patients operated for metastatic spinal cord compression in order to evaluate outcome of surgery and to find predictors of survival. Patients and methods We reviewed the records of 54 consecutive patients with metastatic prostate cancer who were operated for spinal cord compression at Umeå University Hospital. The indication for surgery was neurological deficit due to spinal cord compression. 41 patients had hormone-refractory cancer and 13 patients had previously untreated, hormone-naïve prostate cancer. 29 patients wer... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930293 Thu, 09 Jun 2011 23:00:00 +0100 4930293 http://www.medworm.com/index.php?rid=4930292&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657975%26dopt%3DAbstract Authors: Voigt JD, Mosier M Background It is unclear whether there is a clinical benefit to adding hydroxyapatite (HA) coatings to total knee implants, especially with the tibial component, where failure of the implant more often occurs. A systematic review of the literature was undertaken to identify all prospective randomized trials for determining whether the overall clinical results (as a function of durability, function, and adverse events) favored HA-coated tibial components. Methods A comprehensive literature search was performed for the years 1990 to September 16, 2010. We restricted our search to randomized controlled trials involving participants receiving either an HA-coated tibia or other forms of tibial fixation. The primary outcome measures evaluated were durability, func... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930292 Thu, 09 Jun 2011 23:00:00 +0100 4930292 http://www.medworm.com/index.php?rid=4930291&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21657976%26dopt%3DAbstract Authors: PMID: 21657976 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930291 Thu, 09 Jun 2011 23:00:00 +0100 4930291 http://www.medworm.com/index.php?rid=4930309&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21630329%26dopt%3DAbstract In this study we utilized the imaging approach of FT-IRIS and have shown that a biomaterial formed is compositionally closely related to natural cartilage for long periods in culture. We show that this culture platform can maintain a CTA for extended periods of time (4 years) and under those conditions signs of mineralization can be found. This method of cartilage tissue engineering is a promising method to generate cartilaginous biomaterial and may have potential to be utilized in both cartilage and boney repairs. © 2011 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res. PMID: 21630329 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4930309 Mon, 30 May 2011 23:00:00 +0100 4930309 http://www.medworm.com/index.php?rid=4833842&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561303%26dopt%3DAbstract Authors: Affas F, Nygårds EB, Stiller CO, Wretenberg P, Olofsson C Background and purpose Pain after total knee arthroplasty (TKA) is usually severe, and epidural analgesia or femoral nerve block has been considered to be an effective pain treatment. Recently, local infiltration analgesia (LIA) has become increasingly popular but the outcome of this method regarding the analgesic effect has not been fully evaluated. We compared local infiltration analgesia and femoral block with regard to analgesia and morphine demand during the first 24 h after TKA. Methods 40 patients undergoing TKA under spinal anesthesia were randomized to receive femoral nerve block (group F) or peri- and intraarticular infiltration analgesia (group LIA) with a mixture containing ropivacaine, ketorolac, and epine... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833842 Tue, 10 May 2011 23:00:00 +0100 4833842 http://www.medworm.com/index.php?rid=4833841&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561305%26dopt%3DAbstract Authors: Neut D, Tijdens-Creusen EJ, Bulstra SK, van der Mei HC, Busscher HJ PMID: 21561305 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833841 Tue, 10 May 2011 23:00:00 +0100 4833841 http://www.medworm.com/index.php?rid=4833840&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561306%26dopt%3DAbstract Authors: Puah KL, Tan MH PMID: 21561306 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833840 Tue, 10 May 2011 23:00:00 +0100 4833840 http://www.medworm.com/index.php?rid=4833839&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561307%26dopt%3DAbstract Authors: Murphy TP, Mulhall KJ PMID: 21561307 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833839 Tue, 10 May 2011 23:00:00 +0100 4833839 http://www.medworm.com/index.php?rid=4833838&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561308%26dopt%3DAbstract This study shows lower (or similar) overall mortality with cemented hemiarthroplasty of the hip. PMID: 21561308 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833838 Tue, 10 May 2011 23:00:00 +0100 4833838 http://www.medworm.com/index.php?rid=4833837&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561309%26dopt%3DAbstract Authors: Krieg AH, Lenze U, Speth BM, Hasler CC Background and purpose In the last decade, intramedullary limb lengthening has become a viable alternative to traditional external systems. We retrospectively analyzed the use of an intramedullary motorized nail (Fitbone) in a consecutive series of 32 patients. Patients and methods During the period September 2006 to December 2008, 32 consecutive patients with a median age of 17 (IQR: 15-19) years were treated with a fully implantable, motorized intramedullary lengthening device (Fitbone). The median leg length discrepancy was 35 (IQR: 30-44) mm at the femur (n = 21) and 28 (IQR: 25-30) mm at the tibia (n = 11). Results Leg lengthening was successful in 30 of 32 cases, with no residual relevant discrepancy (± 5 mm). No intraoperative com... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833837 Tue, 10 May 2011 23:00:00 +0100 4833837 http://www.medworm.com/index.php?rid=4833836&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561310%26dopt%3DAbstract Authors: Struijs PA, Oostra RJ, van Rijn RR, Besselaar PP PMID: 21561310 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833836 Tue, 10 May 2011 23:00:00 +0100 4833836 http://www.medworm.com/index.php?rid=4833835&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561311%26dopt%3DAbstract Authors: Husted H, Otte KS, Kristensen BB, Kehlet H Abstract Background and purpose Fast-track surgery has reduced the length of hospital stay (LOS), morbidity, and convalescence in primary hip and knee arthroplasty (TKA). We assessed whether patients undergoing revision TKA for non-septic indications might also benefit from fast-track surgery. Methods 29 patients were operated with 30 revision arthroplasties. Median age was 67 (34-84) years. All patients followed a standardized fast-track set-up designed for primary TKA. We determined the outcome regarding LOS, morbidity, mortality, and satisfaction. Results Median LOS was 2 (1-4) days excluding 1 patient, who was transferred to another hospital for logistical reasons (10 days). None of the patients died within 3 months, and 3 patient... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4833835 Tue, 10 May 2011 23:00:00 +0100 4833835 http://www.medworm.com/index.php?rid=4781030&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504367%26dopt%3DAbstract Authors: Lehmann TG, Engesæter IO, Laborie LB, Rosendahl K, Lie SA, Engesæter LB Background and purpose Slipped capital femoral epiphysis (SCFE) is often treated by surgical fixation; however, no agreement exists regarding technique. We analyzed the outcome of in situ fixation with Steinmann pins. Patients and methods All 67 subjects operated for slipped capital femoral epiphysis at Haukeland University Hospital during the period 1990-2007 were included. All were treated by in situ fixation with 2 or 3 parallel Steinmann pins (8 mm threads at the medial end). The follow-up evaluation consisted of clinical examination and hip radiographs. Radiographic outcome was based on measurements of slip progression, growth of the femoral neck, leg length discrepancy, and signs of avascular necro... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781030 Tue, 19 Apr 2011 23:00:00 +0100 4781030 http://www.medworm.com/index.php?rid=4781029&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504368%26dopt%3DAbstract Authors: Thomsen M, Rozak M, Thomas P PMID: 21504368 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781029 Tue, 19 Apr 2011 23:00:00 +0100 4781029 http://www.medworm.com/index.php?rid=4781028&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504369%26dopt%3DAbstract Authors: Jaatinen JJ, Korhonen RK, Pelttari A, Helminen HJ, Korhonen H, Lappalainen R, Kröger H Background and purpose Amorphous diamond (AD) is a durable and compatible biomaterial for joint prostheses. Knowledge regarding bone growth on AD-coated implants and their early-stage osseointegration is poor. We investigated bone growth on AD-coated cementless intramedullary implants implanted in rats. Titanium was chosen as a reference due to its well-known performance. Materials and methods We placed AD-coated and non-coated titanium implants (R(a) ≈ 0.2 μm) into the femoral bone marrow of 25 rats. The animals were divided in 2 groups according to implant coating and they were killed after 4 or 12 weeks. The osseointegration of the implants was examined from hard tissue specimens by m... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781028 Tue, 19 Apr 2011 23:00:00 +0100 4781028 http://www.medworm.com/index.php?rid=4781038&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504304%26dopt%3DAbstract Authors: Baad-Hansen T, Kold S, Olsen N, Christensen F, Søballe K Background The surface texture, localization, and magnitude of the surface material applied to the femoral stem can facilitate bone ingrowth and influence the survival of total hip arthroplasties. Clinical and radiographic studies have shown superior bone ingrowth in proximally porous-coated stems with a diaphyseal grit-blasted surface in comparison to a smooth diaphyseal surface. Surface textures-especially porous surface material-have been suggested to have a sealing effect against migration of polyethylene debris along the implant-bone interface and to reduce the inflammatory response, leading to a prolonged implant survival. Patients and methods Between 2004 and 2006, we conducted a randomized, controlled trial (RCT... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781038 Mon, 18 Apr 2011 23:00:00 +0100 4781038 http://www.medworm.com/index.php?rid=4781037&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504305%26dopt%3DAbstract We describe the range of radial shortening that occurs following a fracture of the proximal radius, as well as the short-term outcome in these patients. Patients and methods Over an 18-month period, we prospectively assessed all patients with a radiographically confirmed proximal radial fracture. Patients noted to have ipsilateral wrist pain at initial presentation underwent bilateral radiography to determine whether there was disruption of the distal radio-ulnar joint suggestive of an Essex-Lopresti lesion. Outcome was assessed after a mean of 6 (1.5-12) months using clinical and radiographic results, including the Mayo elbow score (MES) and the short musculoskeletal function assessment (SMFA) questionnaire. One patient with a Mason type-I fracture was lost to follow-up after initial pres... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781037 Mon, 18 Apr 2011 23:00:00 +0100 4781037 http://www.medworm.com/index.php?rid=4781036&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504308%26dopt%3DAbstract Authors: Ostermeier S, Stukenborg-Colsman C Background and purpose New implant designs have incorporated a single radius instead of a multiple radius to the femoral component in order to improve the mechanical function after TKA. We investigated the amount of quadriceps force required to extend the knee during an isokinetic extension cycle of different total knee designs, focusing on the radius of the femoral component (single vs. multiple). Methods Human knee specimens (n = 12, median patient age 68 (63-70) years) were tested in a kinematic knee-simulating machine untreated and after implantation of 2 types of knee prosthesis systems, one with a single femoral radius design and one with a multiple femoral radius design. During the test cycle, a hydraulic cylinder, which simulated the ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781036 Mon, 18 Apr 2011 23:00:00 +0100 4781036 http://www.medworm.com/index.php?rid=4781035&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504309%26dopt%3DAbstract In this study, we evaluated the short-term results of computer-navigated knee replacements based on data from the Norwegian Arthroplasty Register. Patients and methods Primary total knee replacements without patella resurfacing, reported to the Norwegian Arthroplasty Register during the years 2005-2008, were evaluated. The 5 most common implants and the 3 most common navigation systems were selected. Cemented, uncemented, and hybrid knees were included. With the risk of revision for any cause as the primary endpoint and intraoperative complications and operating time as secondary outcomes, 1,465 computer-navigated knee replacements (CAS) and 8,214 conventionally operated knee replacements (CON) were compared. Kaplan-Meier survival analysis and Cox regression analysis with adjustment for ag... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781035 Mon, 18 Apr 2011 23:00:00 +0100 4781035 http://www.medworm.com/index.php?rid=4781034&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504310%26dopt%3DAbstract Authors: Walschot LH, Schreurs BW, Verdonschot N, Buma P Background and purpose Porous titanium (Ti) particles can be impacted like cancellous allograft bone particles, and may therefore be used as bone substitute in impaction grafting. We evaluated the effect of impaction and of a thin silicated biphasic calcium phosphate coating on osteoconduction by Ti particles. Methods The bone conduction chamber of Aspenberg was used in goats and filled with various groups of coated or uncoated small Ti particles (diameter 1.0-1.4 mm). Impacted allograft bone particles and empty chambers were used in control groups. Fluorochromes were administered at 4, 8, and 12 weeks. Maximum bone ingrowth distance was evaluated by histomorphometric analysis. Results Histology of Ti particle graft cylinders sho... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781034 Mon, 18 Apr 2011 23:00:00 +0100 4781034 http://www.medworm.com/index.php?rid=4781033&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504313%26dopt%3DAbstract Authors: Scheer JH, Adolfsson LE Background and purpose Mechanisms of injury to ulnar-sided ligaments (stabilizing the distal radioulnar joint and the ulna to the carpus) associated with dorsally displaced distal radius fractures are poorly described. We investigated the injury patterns in a human cadaver fracture model. Methods Fresh frozen human cadaver arms were used. A dorsal open-wedge osteotomy was performed in the distal radius. In 8 specimens, pressure was applied to the palm with the wrist in dorsiflexion and ulnar-sided stabilizing structures subsequently severed. Dorsal angulation was measured on digitized radiographs. In 8 other specimens, the triangular fibrocartilage complex (TFCC) was forced into rupture by axially loading the forearm with the wrist in dorsiflexion. The ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781033 Mon, 18 Apr 2011 23:00:00 +0100 4781033 http://www.medworm.com/index.php?rid=4781032&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504335%26dopt%3DAbstract Authors: Wynn-Jones H, Macnair R, Wimhurst J, Chirodian N, Derbyshire B, Toms A, Cahir J Background and purpose Adverse reactions to metal debris have been reported to be a cause of pain in metal-on-metal hip arthroplasty. We assessed the incidence of both symptomatic and asymptomatic adverse reactions in a consecutive series of patients with a modern large-head metal-on-metal hip arthroplasty. Methods We studied the early clinical results and results of routine metal artifact-reduction MRI screening in a series of 79 large-head metal-on-metal hip arthroplasties (ASR; DePuy, Leeds, UK) in 68 patients. 75 hips were MRI scanned at mean 31 (12-52) months after surgery. Results 27 of 75 hips had MRI-detected metal debris-related abnormalities, of which 5 were mild, 18 moderate, and 4 sever... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781032 Mon, 18 Apr 2011 23:00:00 +0100 4781032 http://www.medworm.com/index.php?rid=4781031&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21504344%26dopt%3DAbstract Authors: Bøe B, Heier T, Nordsletten L Background and purpose Dual-energy X-ray absorptiometry (DXA) is a precise method to study changes in bone mineral density (BMD), including the pattern of bone remodeling around an implant. Results from implant studies are usually presented as changes in BMD as a function of time. The baseline and reference value for such calculations is the first measurement after the operation. The baseline measurement has been performed at different time points in different studies. If there is rapid bone loss immediately after an operation, this will influence the reference value and hence the results. To evaluate DXA as a method, we studied the very early changes by doing 3 DXA measurements within the first 2 weeks after surgery. Patients and methods We incl... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4781031 Mon, 18 Apr 2011 23:00:00 +0100 4781031 http://www.medworm.com/index.php?rid=4732114&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21463220%26dopt%3DAbstract Authors: Labek G, Frischhut S, Schlichtherle R, Williams A, Thaler M Background and purpose The validity of various data sources for the assessment of the outcome quality of medical devices was investigated by comparative analysis of the published data sources available for a sample of implants. It was the aim of the study to determine the performance of this implant and to identify potential bias factors inherent to the various datasets. Methods A comprehensive literature search was carried out from English-language, peer-reviewed journals and worldwide reports from national arthroplasty registers. Publications from Medline-listed journals were included. The main parameter was revision rate, calculated as "revisions per 100 observed component years" to allow adjusted direct comparison... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4732114 Thu, 31 Mar 2011 23:00:00 +0100 4732114 http://www.medworm.com/index.php?rid=4732113&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21463221%26dopt%3DAbstract Authors: Tranberg R, Saari T, Zügner R, Kärrholm J Background and purpose Invasive methods are more reproducible and accurate than non-invasive ones when it comes to recording knee kinematics, but they are usually less accessible and less safe, mainly due to risk of infection. For this reason, non-invasive methods with passive markers are widely used. With these methods, varying marker sets based on a number of single markers, or sets of markers, known as clusters, are used to track body segments. We compared one invasive method-radiostereometric analysis-with a non-invasive method, an optical tracking system with 15 skin-mounted markers. Methods 9 subjects (10 knees) were investigated simultaneously with a dynamic RSA system and a motion-capture system while performing an active kne... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4732113 Thu, 31 Mar 2011 23:00:00 +0100 4732113 http://www.medworm.com/index.php?rid=4732112&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21463222%26dopt%3DAbstract Authors: Claes L, Ignatius A, Lechner R, Gebhard F, Kraus M, Baumgärtel S, Recknagel S, Krischak GD Background and purpose There is some clinical evidence that fracture healing is impaired in multiply injured patients. Nothing is known, however, about the effects of various types of injuries and their contribution to a possible disturbance of the fracture-healing process. We investigated the effect of a thoracic trauma and an additional soft-tissue trauma on fracture healing in a rat tibia model. Methods 3 groups of rats were operated: group A with a simple fracture of the tibia and fibula, group B with a fracture and an additional thoracic trauma, and group C with a fracture, thoracic trauma, and an additional soft-tissue trauma. The fracture and the soft-tissue injury were produced ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4732112 Thu, 31 Mar 2011 23:00:00 +0100 4732112 http://www.medworm.com/index.php?rid=4732111&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21463223%26dopt%3DAbstract Authors: Schagemann JC, Hunold P, Russlies M, Mittelstaedt H PMID: 21463223 [PubMed - in process] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4732111 Thu, 31 Mar 2011 23:00:00 +0100 4732111 http://www.medworm.com/index.php?rid=4732110&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21463224%26dopt%3DAbstract Authors: Tulner S, Klinkenbijl M, Albers G PMID: 21463224 [PubMed - in process] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4732110 Thu, 31 Mar 2011 23:00:00 +0100 4732110 http://www.medworm.com/index.php?rid=4676326&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434845%26dopt%3DAbstract Authors: Baad-Hansen T, Kold S, Nielsen PT, Laursen MB, Christensen PH, Soballe K Background Trabecular metal has shown promising results in experimental studies of bone ingrowth. Several clinical studies support these results. However, until now, no randomized clinical radiostereometric analysis (RSA) studies have been published. In this randomized RSA trial, we compared a new acetabular cup with a surface made of tantalum trabecular metal and a cup with a titanium fiber-mesh surface. Patients and methods Between 2004 and 2006, we operated 60 patients with noninflammatory hip arthritis. The patients were randomized to receive either an uncemented cup with a titanium fiber-mesh surface (Trilogy cup) or a cup with a trabecular tantalum surface (Monoblock cup). After 2 years, 50 patients... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676326 Fri, 25 Mar 2011 00:00:00 +0100 4676326 http://www.medworm.com/index.php?rid=4676323&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434846%26dopt%3DAbstract Authors: Sera S, Ishikawa M, Adachi N, Yasunaga Y, Ochi M Background and purpose Drainage after surgery is commonly used, and the contents are generally discarded as clinical waste. We analyzed closed suction drainage fluid from hip arthroplasty patients to determine whether any multipotent stem cells were present that could be used as a source of cells for tissue regeneration. Methods Drainage fluid was obtained from 14 patients after hip arthroplasty on the day of surgery, the next day, and 2 days after surgery. Peripheral blood and bone marrow from the iliac crest were also obtained from the same patients during surgery. These samples were examined using regular flow cytometric profiling, and we performed quantitative immunoassays of stromal-derived factor-1 (SDF1) levels in the pla... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676323 Fri, 25 Mar 2011 00:00:00 +0100 4676323 http://www.medworm.com/index.php?rid=4676320&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21438671%26dopt%3DAbstract Authors: Agholme F, Aspenberg P Abstract Wnt signaling is a ubiquitous system for intercellular communication, with multiple functions during development and in homeostasis of the body. It comprises several ligands, receptors, and inhibitors. Some molecules, such as sclerostin, appear to have bone-specific functions, and can be targeted by potential drugs. Now, ongoing clinical trials are testing these drugs as treatments for osteoporosis. Animal studies have also suggested that these drugs can accelerate fracture healing and implant fixation. This brief overview focuses on currently available information on the effects of manipulations of Wnt signaling on bone healing. PMID: 21438671 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676320 Fri, 25 Mar 2011 00:00:00 +0100 4676320 http://www.medworm.com/index.php?rid=4676342&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21428845%26dopt%3DAbstract Authors: Bøgehøj MF, Emmeluth C, Overgaard S Introduction Microdialysis can detect ischemia in soft tissue. In a previous study, we have shown the development of ischemia in the femoral head removed from patients undergoing total hip replacement. That study also raised some methodological questions that this study tries to answer: what is happening in the dead space around the catheter in the drill canal, and is there an equilibrium period after the insertion of the catheter? Material and methods In an ex-vivo study using 5 syringes with 5 mL human blood, a microdialysis catheter was inserted and microdialysis was performed over 3 h. In an in-vivo study, a drill hole was made in the proximal part of the femur in 6 mature Göttingen minipigs and microdialysis was performed over 3 h. T... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676342 Thu, 24 Mar 2011 00:00:00 +0100 4676342 http://www.medworm.com/index.php?rid=4676341&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21428847%26dopt%3DAbstract Authors: Sköldenberg O, Odquist M Introduction Standard radiostereometric analysis of prosthetic migration requires that tantalum beads are inserted into the implant. For manufacturing reasons, this is not possible for humeral head resurfacing implants. We therefore used marker-free radiostereometry, developed for metal-backed acetabular cups, on a dummy model to validate the method for a humeral head resurfacing prosthesis. Material and methods 3 hemispherical resurfacing prostheses of different sizes were marked with tantalum beads and mounted in a sawbone. Standard and marker-free radiostereometry was then done repeatedly with gradual shifts of position of the prosthesis between each analysis. The marker-free algorithm was then compared to the standard to determine the accuracy. Re... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676341 Thu, 24 Mar 2011 00:00:00 +0100 4676341 http://www.medworm.com/index.php?rid=4676340&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434760%26dopt%3DAbstract Authors: Labek G, Sekyra K, Pawelka W, Janda W, Stöckl B Background and purpose The reproducibility of results and potential confounders in sample-based studies is important to consider in the assessment of studies. Comprehensive arthroplasty registers could serve as a reference dataset for comparative analyses. We analyzed an implant that is frequently used worldwide, the Oxford unicompartmental knee replacement, in order to identify potential confounders inherent in the datasets and to evaluate the outcome achieved with this implant. Methods We performed a structured literature review of the data published on the revision rate of the Oxford medial unicompartmental arthroplasty. Both clinical follow-up studies and worldwide registry data were included. Confidence intervals were calcu... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676340 Thu, 24 Mar 2011 00:00:00 +0100 4676340 http://www.medworm.com/index.php?rid=4676339&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434761%26dopt%3DAbstract Authors: Foldager CB, Nielsen AB, Munir S, Ulrich-Vinther M, Søballe K, Bünger C, Lind M Background and purpose In vitro expansion of autologous chondrocytes is an essential part of many clinically used cartilage repair treatments. Native chondrocytes reside in a 3-dimensional (3D) network and are exposed to low levels of oxygen. We compared monolayer culture to combined 3D and hypoxic culture using quantitative gene expression analysis. Methods Cartilage biopsies were collected from the intercondylar groove in the distal femur from 12 patients with healthy cartilage. Cells were used for either monolayer or scaffold culture. The scaffolds were clinically available MPEG-PLGA scaffolds (ASEED). After harvesting of cells for baseline investigation, the remainder was divided into 3 group... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676339 Thu, 24 Mar 2011 00:00:00 +0100 4676339 http://www.medworm.com/index.php?rid=4676338&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434763%26dopt%3DAbstract Authors: Silverplats K, Lind B, Zoega B, Halldin K, Gellerstedt M, Rutberg L, Brisby H Background and purpose Health-related quality of life (HRQoL) instruments have been of increasing interest for evaluation of medical treatments over the past 10-15 years. In this prospective, long-term follow-up study we investigated the influence of preoperative factors and the change in HRQoL over time after lumbar disc herniation surgery. Methods 117 patients surgically treated for lumbar disc herniation (L4-L5 or L5-S1) were evaluated with a self-completion HRQoL instrument (EQ-5D) preoperatively, after 2 years (96 patients) and after 7 years (89 patients). Baseline data (age, sex, duration of leg pain, surgical level) and degree of leg and back pain (VAS) were obtained preoperatively. The mean a... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676338 Thu, 24 Mar 2011 00:00:00 +0100 4676338 http://www.medworm.com/index.php?rid=4676337&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434768%26dopt%3DAbstract Authors: Petruskevicius J, Lind-Hansen T, Aleksyniene R, Nyengaard JR, Nielsen PT, Søballe K Background and purpose A proximal stem centralizer may be beneficial regarding cementing pressures, cement penetration, and stem alignment. We measured these parameters when cementing a mat-surfaced femoral component with and without the use of a proximal stem centralizer. Material and methods 8 femoral prostheses with proximal centralizers and 8 femoral prostheses without proximal centralizers were cemented according to third-generation cementing technique in 8 pairs of embalmed cadaveric femora. We recorded intramedullary pressures (peak levels, the area under the pressure curves and mean pressure) with 6 pressure transducers during stem cementation. Computer tomographic scanning of specimen... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676337 Thu, 24 Mar 2011 00:00:00 +0100 4676337 http://www.medworm.com/index.php?rid=4676336&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434769%26dopt%3DAbstract Authors: Belfrage O, Flivik G, Sundberg M, Kesteris U, Tägil M Background and purpose The remodeling of morselized bone grafts in revision surgery can be enhanced by an anabolic substance such as a bone morphogenetic protein (BMP). On the other hand, BMPs boost catabolism and might cause a premature resorption, both of the graft and of the new-formed bone. Bisphosphonates inactivate osteoclasts and can be used to control the resorption. We studied a combination of both drugs as a local admix to a cancellous allograft. Methods Cancellous bone allografts were harvested and freeze-dried. Either saline, BMP-7, the bisphosphonate zoledronate, or a combination of BMP-7 and zoledronate were added in solution. The grafts were placed in bone conduction chambers and implanted in the proximal ti... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676336 Thu, 24 Mar 2011 00:00:00 +0100 4676336 http://www.medworm.com/index.php?rid=4676335&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434781%26dopt%3DAbstract Authors: Stilling M, Madsen F, Odgaard A, Rømer L, Andersen NT, Rahbek O, Søballe K Background and purpose Lasting stability of cementless implants depends on osseointegration into the implant surface, and long-term implant fixation can be predicted using radiostereometric analysis (RSA) with short-term follow-up. We hypothesized that there would be improved fixation of high-porosity trabecular metal (TM) tibial components compared to low-porosity titanium pegged porous fiber-metal (Ti) polyethylene metal backings. Methods In a prospective, parallel-group, randomized unblinded clinical trial, we compared cementless tibial components in patients aged 70 years and younger with osteoarthritis. The pre-study sample size calculation was 22 patients per group. 25 TM tibial components were ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676335 Thu, 24 Mar 2011 00:00:00 +0100 4676335 http://www.medworm.com/index.php?rid=4676334&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434783%26dopt%3DAbstract Authors: Bisseling P, Smolders JM, Hol A, van Susante JL Background and purpose Hip resurfacing arthroplasty (RHA) is done in patients who often have a high preference for the method. This preference can influence the clinical outcome and satisfaction. We evaluated the potential influence of this preference bias. Patients and methods From an ongoing randomized trial comparing RHA with total hip arthroplasty, 28 consecutive patients (28 hips) who had been allocated to an RHA were characterized as the "randomized" group. 22 other patients (24 hips) who had refused participation and had especially requested an RHA were characterized as the "preference" group. Harris hip score (HHS), Oxford hip score (OHS), University of California at Los Angeles activity scale (UCLA), Short Form 12 (SF-12... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676334 Thu, 24 Mar 2011 00:00:00 +0100 4676334 http://www.medworm.com/index.php?rid=4676333&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434784%26dopt%3DAbstract Authors: Smeland S, Bruland OS, Hjorth L, Brosjö O, Bjerkehagen B, Osterlundh G, Jakobson A, Hall KS, Monge OR, Björk O, Alvegaard TA Background and purpose The Scandinavian Sarcoma Group (SSG) XIV protocol is based on experience from previous SSG trials and other osteosarcoma intergroup trials, and has been considered the best standard of care for patients with extremity localized, non-metastatic osteosarcoma. We analyzed the outcome in 63 consecutive patients. Patients and methods From 2001 through 2005, 63 patients recruited from centers in Sweden, Norway, and Finland were included. They received preoperative chemotherapy consisting of 2 cycles of paired methotrexate (12 g/m(2)), cisplatin (90 mg/m(2)), and doxorubicin (75 mg/m(2)). 3 cycles were administered postoperatively, and ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676333 Thu, 24 Mar 2011 00:00:00 +0100 4676333 http://www.medworm.com/index.php?rid=4676332&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434789%26dopt%3DAbstract Authors: Zaikova O, Fosså SD, Bruland OS, Giercksky KE, Sandstad B, Skjeldal S Background and purpose Radiotherapy (RT) remains the cornerstone of management of spine metastases (SM), even though surgery is a well-established treatment for selected patients. We compared the use of RT and surgery in a population-based cohort of patients with SM, investigated pre-treatment factors that were associated with use of these treatment modalities, and examined survival. Patients and methods 903 patients in the south-eastern Norway who were admitted for RT or surgery for SM for the first time during an 18-month period in 2007-2008 were identified and their medical records were reviewed. Results The primary treatment was surgery in 58 patients and RT in 845 patients, including 704 multiple-fract... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676332 Thu, 24 Mar 2011 00:00:00 +0100 4676332 http://www.medworm.com/index.php?rid=4676331&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434790%26dopt%3DAbstract Authors: Palm H, Lysén C, Krasheninnikoff M, Holck K, Jacobsen S, Gebuhr P Background and purpose In recent years, intramedullary nails (INs) for the treatment of pertrochanteric hip fractures have gained prominence relative to conventional, sliding hip screws (SHSs). There is little empirical background for this development, however. A previous series of ours suggested that the use of SHS was not adequate in situations with fragile or fractured lateral femoral walls, where it often led to lack of healing in a maximally telescoped position. We hypothesized that INs would be the superior implant in these specific circumstances. Methods We retrospectively examined 311 consecutive patients treated in our department between 2002 and 2008, with either an IN (n = 158) or an SHS (n = 153) mo... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676331 Thu, 24 Mar 2011 00:00:00 +0100 4676331 http://www.medworm.com/index.php?rid=4676330&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434791%26dopt%3DAbstract Authors: Björnsson HC, Norlin R, Johansson K, Adolfsson LE Background and purpose Few authors have considered the outcome after acute traumatic rotator cuff tears in previously asymptomatic patients. We investigated whether delay of surgery, age at repair, and the number of cuff tendons involved affect the structural and clinical outcome. Patients and methods 42 patients with pseudoparalysis after trauma and no previous history of shoulder symptoms were included. A full-thickness tear in at least 1 of the rotator cuff tendons was diagnosed in all patients. Mean time to surgery was 38 (6-91) days. Follow-up at a mean of 39 (12-108) months after surgery included ultrasound, plain radiographs, Constant-Murley score, DASH score, and western Ontario rotator cuff (WORC) score. Results At fo... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676330 Thu, 24 Mar 2011 00:00:00 +0100 4676330 http://www.medworm.com/index.php?rid=4676329&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434792%26dopt%3DAbstract Authors: Weiss RJ, Stark A, Kärrholm J Background and purpose Modular cementless revision prostheses are being used with increasing frequency. In this paper, we review risk factors for the outcome of the Link MP stem and report implant survival compared to conventional cemented long-stem hip revision arthroplasties. Patients and methods We used data recorded in the Swedish Hip Arthroplasty Register. 812 consecutive revisions with the MP stem (mean follow-up time 3.4 years) and a control group with 1,073 cemented long stems (mean follow-up time 4.2 years) were included. Kaplan-Meier analysis was used to determine implant survival. The Cox regression model was used to study risk factors for reoperation and revision. Results The mean age at revision surgery for the MP stem was 72 (SD 11)... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676329 Thu, 24 Mar 2011 00:00:00 +0100 4676329 http://www.medworm.com/index.php?rid=4676328&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434808%26dopt%3DAbstract Authors: Engesæter IO, Lehmann T, Laborie LB, Lie SA, Rosendahl K, Engesæter LB Background and purpose Dysplasia of the hip increases the risk of secondary degenerative change and subsequent total hip replacement. Here we report on age at diagnosis of dysplasia, previous treatment, and quality of life for patients born after 1967 and registered with a total hip replacement due to dysplasia in the Norwegian Arthroplasty Register. We also used the medical records to validate the diagnosis reported by the orthopedic surgeon to the register. Methods Subjects born after January 1, 1967 and registered with a primary total hip replacement in the Norwegian Arthroplasty Register during the period 1987-2007 (n = 713) were included in the study. Data on hip symptoms and quality of life (EQ-5D) ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676328 Thu, 24 Mar 2011 00:00:00 +0100 4676328 http://www.medworm.com/index.php?rid=4676327&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21434811%26dopt%3DAbstract Authors: Sigmundsson FG, Kang XP, Jönsson B, Strömqvist B Background and purpose MRI is the modality of choice when diagnosing spinal stenosis but it also shows that stenosis is prevalent in asymptomatic subjects over 60. The relationship between preoperative health-related quality of life, functional status, leg and back pain, and the objectively measured dural sac area in single and multilevel stenosis is unknown. We assessed this relationship in a prospective study. Patients and methods The cohort included 109 consecutive patients with central spinal stenosis operated on with decompressive laminectomy or laminotomy. Preoperatively, all patients completed the questionnaires for EQ-5D, SF-36, Oswestry disability index (ODI), estimated walking distance and leg and back pain (VAS). Th... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4676327 Thu, 24 Mar 2011 00:00:00 +0100 4676327 http://www.medworm.com/index.php?rid=4442300&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281257%26dopt%3DAbstract Authors: Andersen C, Winding TN, Vesterby MS Background and purpose Previous studies have shown that there is a correlation between arthroscopic experience and performance on a virtual-reality (VR) unit. We analyzed the development inexperienced surgeons went through during VR training of shoulder arthroscopy. Methods 14 inexperienced surgeons from Silkeborg Regional Hospital were randomized into an intervention group and a control group. 7 experienced surgeons constituted another control group. All were tested twice on insightMIST-an advanced arthroscopic VR trainer-within a period of 6-15 days. The intervention group also received a 5-hour training program on the VR unit. Results The average time for the arthroscopy in the intervention group was reduced from 720 (SD 239) seconds to 2... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442300 Tue, 01 Feb 2011 00:00:00 +0100 4442300 http://www.medworm.com/index.php?rid=4442299&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281259%26dopt%3DAbstract This study of metal-meshed hip-simulated acetabular cups shows that CT has the capacity for reliable measurement of linear wear of acetabular cups at a clinically relevant level of accuracy. PMID: 21281259 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442299 Tue, 01 Feb 2011 00:00:00 +0100 4442299 http://www.medworm.com/index.php?rid=4442298&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281260%26dopt%3DAbstract This study was based on data recorded in the Karolinska Skeletal Metastasis Register. The study period was 1987-2006. We identified 98 lung cancer patients (52 females). The median age at surgery was 62 (34-88) years. 78 lesions were located in the femur or spine. Results The median survival time after surgery was 3 (0-127) months. The cumulative 12-month survival after surgery was 13% (95% CI: 6-20). There was a difference between the survival after spinal surgery (2 months) and after extremity surgery (4 months) (p = 0.03). Complete pathological fracture in non-spinal metastases (50 patients) was an independent negative predictor of survival (hazard ratio (HR) = 1.8, 95% CI: 1-3). 16 of 31 patients with spinal metastases experienced a considerable improvement in their neurological functi... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442298 Tue, 01 Feb 2011 00:00:00 +0100 4442298 http://www.medworm.com/index.php?rid=4442297&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281262%26dopt%3DAbstract Authors: Wilcke MK, Abbaszadegan H, Adolphson PY Background and purpose Promising results have been reported after volar locked plating of unstable dorsally displaced distal radius fractures. We investigated whether volar locked plating results in better patient-perceived, objective functional and radiographic outcomes compared to the less invasive external fixation. Patients and methods 63 patients under 70 years of age, with an unstable extra-articular or non-comminuted intra-articular dorsally displaced distal radius fracture, were randomized to volar locked plating (n = 33) or bridging external fixation. Patient-perceived outcome was assessed with the Disability of the Arm, Shoulder, and Hand (DASH) questionnaire and the Patient-Rated Wrist Evaluation (PRWE) questionnaire. Results ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442297 Tue, 01 Feb 2011 00:00:00 +0100 4442297 http://www.medworm.com/index.php?rid=4442296&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281263%26dopt%3DAbstract Authors: Takács IM, Swierstra BA PMID: 21281263 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442296 Tue, 01 Feb 2011 00:00:00 +0100 4442296 http://www.medworm.com/index.php?rid=4442295&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281264%26dopt%3DAbstract Authors: Cenni E, Fotia C, Rustemi E, Yuasa K, Caltavuturo G, Giunti A, Baldini N Background and purpose Thrombophilia represents a risk factor both for idiopathic and secondary osteonecrosis (ON). We evaluated whether clotting changes in idiopathic ON were different from corticosteroid-associated ON. As platelet-rich plasma has been proposed as an adjuvant in surgery, we also assessed whether platelet and serum growth factors were similar to those in healthy subjects. Methods 18 patients with idiopathic ON and 18 with corticosteroid-associated ON were compared with 44 controls for acquired and inherited thrombophilia. Platelet factor 4 (PF4), transforming growth factor-β1, platelet-derived growth factor-BB (PDGF-BB), and vascular endothelial growth factor were assayed in the supernat... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442295 Tue, 01 Feb 2011 00:00:00 +0100 4442295 http://www.medworm.com/index.php?rid=4442294&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281265%26dopt%3DAbstract Authors: Mereddy P PMID: 21281265 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442294 Tue, 01 Feb 2011 00:00:00 +0100 4442294 http://www.medworm.com/index.php?rid=4442293&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281266%26dopt%3DAbstract Authors: Løken S, Arøen A, Engebretsen L PMID: 21281266 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442293 Tue, 01 Feb 2011 00:00:00 +0100 4442293 http://www.medworm.com/index.php?rid=4442292&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21288143%26dopt%3DAbstract Authors: Dimmen SR PMID: 21288143 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4442292 Tue, 01 Feb 2011 00:00:00 +0100 4442292 http://www.medworm.com/index.php?rid=4378199&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189097%26dopt%3DAbstract Authors: Baek SW, Choi CH PMID: 21189097 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378199 Wed, 29 Dec 2010 00:00:00 +0100 4378199 http://www.medworm.com/index.php?rid=4378198&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189098%26dopt%3DAbstract Authors: Skyttä ET, Jarkko L, Antti E, Huhtala H, Ville R Background and purpose The use of hip arthroplasties is evidently increasing, but there are few published data on the incidence in young patients. Methods We used data on total and resurfacing hip arthroplasties (THAs and RHAs) from the Finnish Arthroplasty Register and population data from Statistics Finland to analyze the incidences of THA and RHA in patients aged 30-59 years in Finland, for the period 1980 through 2007. Results The combined incidences of THAs and RHAs among 30- to 59-year-old inhabitants increased from 9.5 per 10(5) inhabitants in 1980 to 61 per 10(5) inhabitants in 2007. Initially, the incidence of THA was higher in women than men, but since the mid-90s the incidences were similar. The incidence increased i... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378198 Wed, 29 Dec 2010 00:00:00 +0100 4378198 http://www.medworm.com/index.php?rid=4378197&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189099%26dopt%3DAbstract Authors: De Man FH, Sendi P, Zimmerli W, Maurer TB, Ochsner PE, Ilchmann T Background and purpose Successful treatment of prosthetic hip joint infection (PI) means elimination of infection and restored hip function. However, functional outcome is rarely studied. We analyzed the outcome of the strict use of a treatment algorithm for PI. Patients and methods The study groups included 22 hips with 1-stage exchange for PI (group 1), 22 matched hips revised for aseptic loosening (controls), and 50 hips with 2-stage exchange (group 2). Relapse of infection, Harris hip score (HHS), limping, use of crutches, reoperations, complications, and radiographic changes were compared between the groups. Results There was 1 relapse of infection, which occurred in group 2. In group 1, the mean HHS was 84... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378197 Wed, 29 Dec 2010 00:00:00 +0100 4378197 http://www.medworm.com/index.php?rid=4378196&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189100%26dopt%3DAbstract Authors: Abul-Kasim K, Ohlin A Background and purpose There are no reports in the literature on the influence of learning on the pedicle screw insertion. We studied the effect of learning on the rate of screw misplacement in patients with adolescent idiopathic scoliosis treated with segmental pedicle screw fixation. Method We retrospectively evaluated low-dose spine computed tomography of 116 consecutive patients (aged 16 (12-24) years, 94 females) who were operated during 4 periods over 2005-2009 (group 1: patients operated autumn 2005-2006; group 2: 2007; group 3: 2008; and group 4: 2009). 5 types of misplacement were recorded: medial cortical perforation, lateral cortical perforation, anterior cortical perforation of the vertebral body, endplate perforation, and perforation of the n... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378196 Wed, 29 Dec 2010 00:00:00 +0100 4378196 http://www.medworm.com/index.php?rid=4378195&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189109%26dopt%3DAbstract Authors: Bøe BG, Röhrl SM, Heier T, Snorrason F, Nordsletten L Background and purpose Plasma-sprayed hydroxyapatite (HA) is a successful coating for fixation of uncemented femoral stems. There may be alternative coatings with advantages in bone remodeling and transport of bone-active substances. We investigated whether an electrochemically deposited hydroxyapatite, Bonemaster (BM), might be a safe alternative in total hip arthroplasty. Our hypothesis was that the new coating would not be inferior to the conventional one. Patients and methods 50 patients (55 hips) were included. The stem was tapered and porous-coated proximally. On top of the porous coating was either HA or BM. Patients were evaluated postoperatively and after 3, 6, 12, and 24 months to measure fixation by radiostereo... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378195 Wed, 29 Dec 2010 00:00:00 +0100 4378195 http://www.medworm.com/index.php?rid=4378194&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189110%26dopt%3DAbstract Authors: Hailer NP, Blaheta RA, Dahlstrand H, Stark A Background and purpose Following metal-on-metal hip arthroplasty (THA), immunological reactions including changes in lymphocyte populations, aseptic loosening, and lymphocytic pseudotumors occur. We hypothesized that changes in lymphocyte subpopulations would be associated with elevated metal ion concentrations. Methods A randomized trial involving 85 patients matched for age and sex and randomized to receiving metal-on-metal (n = 41) or metal-on-polyethylene total hip arthroplasty (n = 44) was conducted. 36 patients were eligible for follow-up after mean 7 (6-8) years. Concentrations of chromium and cobalt were analyzed by high-resolution inductively coupled plasma mass spectrometry. Leukocyte subpopulations and immunoglobulins in ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378194 Wed, 29 Dec 2010 00:00:00 +0100 4378194 http://www.medworm.com/index.php?rid=4378193&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189111%26dopt%3DAbstract Authors: Benum P Background and purpose Total necrosis of the femoral head after infection in children during their first months of life gives a dislocated hip with severe leg shortening. A new femoral head can be achieved with subtrochanteric osteotomy and transposition of the apophysis of the greater trochanter into the acetabulum. Previous reports have dealt with short-term results (up to 12 years). Here I present some results of this procedure 15-24 years after operation. Patients and methods 4 children aged 1-6 years with complete necrosis of the femoral head were operated on with transposition of the greater trochanter. Secondary shelf plasty was performed later in 1 child, distal femoral epiphysiodesis in another, and femoral bone lengthening in 1 child. The mean follow-up perio... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378193 Wed, 29 Dec 2010 00:00:00 +0100 4378193 http://www.medworm.com/index.php?rid=4378192&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189112%26dopt%3DAbstract Authors: Jansson KA, Granath F Background and purpose Population data on mortality and life expectancy are generally available for most countries. However, no longitudinal data based on the health-related quality of life outcome from the EQ-5D instrument have been reported for orthopedic patients. We assessed the effect of orthopedic surgery as measured by EQ-5D. Methods We analyzed EQ-5D data from 2,444 patients who were operated at the Department of Orthopedic Surgery at Karolinska University Hospital, 2001-2005. We also made a comparison between results from this cohort and those from a Swedish EQ-5D population survey. Results The mean EQ-5D (index) score improved from 0.54 to 0.72. Hip and knee arthroplasty, operations related to previous surgery, trauma-related procedures, and rhe... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378192 Wed, 29 Dec 2010 00:00:00 +0100 4378192 http://www.medworm.com/index.php?rid=4378191&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189113%26dopt%3DAbstract In this study, we wanted to determine whether outcomes were different in responding and non-responding patients who were included in a clinical spine surgery registry, at two years of follow-up. In addition, we wanted to identify risk factors for failure to respond. Methods 633 patients who were operated for degenerative disorders of the lumbar spine were followed for 2 years using a local clinical spine registry. Those who did not attend the clinic and those who did not answer a postal questionnaire-for whom 2 years of outcome data were missing-and who would be lost to follow-up according to the standard procedures of the registry protocols, were defined as non-respondents. They were traced and interviewed by telephone. Outcome measures were: improvement in health-related quality of life ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4378191 Wed, 29 Dec 2010 00:00:00 +0100 4378191 http://www.medworm.com/index.php?rid=4289583&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21142822%26dopt%3DAbstract Authors: Winkler T, Roth PV, Matziolis G, Schumann MR, Hahn S, Strube P, Stoltenburg-Didinger G, Perka C, Duda GN, Tohtz SV Background and purpose Animal models of skeletal muscle injury should be thoroughly described and should mimic the clinical situation. We established a model of a critical size crush injury of the soleus muscle in rats. The aim was to describe the time course of skeletal muscle regeneration using mechanical, histological, and magnetic resonance (MR) tomographic methods. Methods Left soleus muscles of 36 Sprague-Dawley rats were crushed in situ in a standardized manner. We scanned the lower legs of 6 animals by 7-tesla MR one week, 4 weeks, and 8 weeks after trauma. Regeneration was evaluated at these times by in vivo measurement of muscle contraction forces after ... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4289583 Mon, 13 Dec 2010 00:00:00 +0100 4289583 http://www.medworm.com/index.php?rid=4289533&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21142823%26dopt%3DAbstract Authors: Kirjavainen MO, Nietosvaara Y, Rautakorpi SM, Remes VM, Pöyhiä TH, Helenius IJ, Peltonen JI Background There is little information about the range of motion (ROM) and strength of the affected upper limbs of patients with permanent brachial plexus birth palsy. Patients and methods 107 patients who had brachial plexus surgery in Finland between 1971 and 1998 were investigated in this population-based, cross-sectional, 12-year follow-up study. During the follow-up, 59 patients underwent secondary procedures. ROM and isometric strength of the shoulders, elbows, wrists, and thumbs were measured. Ratios for ROM and strength between the affected and unaffected sides were calculated. Results 61 patients (57%) had no active shoulder external rotation (median 0° (-75-90)). Median act... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4289533 Mon, 13 Dec 2010 00:00:00 +0100 4289533 http://www.medworm.com/index.php?rid=4289519&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21142824%26dopt%3DAbstract Authors: Osugi K, Miwa S, Marukawa S, Marukawa K, Kawaguchi Y, Nakato S PMID: 21142824 [PubMed - as supplied by publisher] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4289519 Mon, 13 Dec 2010 00:00:00 +0100 4289519 http://www.medworm.com/index.php?rid=4237730&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110699%26dopt%3DAbstract Authors: Fevang BT, Lie SA, Havelin LI, Engesæter LB, Furnes O Background and purpose Over the past 20 years, several changes in treatment policy and treatment options have taken place regarding hip replacement. For this reason, we wanted to investigate the results after hip replacement in terms of revision rate, during a 21-year period among hip replacements reported to the Norwegian Arthroplasty Register. Methods 110,882 primary total hip replacements were reported to the Norwegian Arthroplasty Register from 1987 through 2007. Risk of revision during the time periods 1993-1997, 1998-2002, and 2003-2007 was compared to that of the reference period 1987-1992. Adjusted Cox regression analyses were performed to compare the risk of revision in different time periods and extended analyses... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237730 Wed, 01 Dec 2010 00:00:00 +0100 4237730 http://www.medworm.com/index.php?rid=4237729&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110700%26dopt%3DAbstract Authors: Jämsen E, Furnes O, Engesæter LB, Konttinen YT, Odgaard A, Stefánsdóttir A, Lidgren L PMID: 21110700 [PubMed - in process] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237729 Wed, 01 Dec 2010 00:00:00 +0100 4237729 http://www.medworm.com/index.php?rid=4237728&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110701%26dopt%3DAbstract Authors: Esteban J, Molina-Manso D, Spiliopoulou I, Cordero-Ampuero J, Fernández-Roblas R, Foka A, Gómez-Barrena E Background Biofilms are considered the key factor in the development of implant-related infections. However, only a few reports have dealt with the ability of organisms isolated from such infections to develop biofilms in vitro. Methods We evaluated different phenotypic techniques (2 microtiter plate assays and confocal laser scanning microscopy (CLSM) and genotypic techniques (detection of the ica operon) related to biofilm development by clinical isolates of Staphylococcus spp. Results All 26 strains tested (from 23 specimens) were biofilm producers. Stepanovic test detected biofilm formation in 85% of the strains, microtiter plate assay in 65%, and CLSM in 39%. The ic... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237728 Wed, 01 Dec 2010 00:00:00 +0100 4237728 http://www.medworm.com/index.php?rid=4237727&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110702%26dopt%3DAbstract Authors: van Oldenrijk J, Hoogland PV, Tuijthof GJ, Corveleijn R, Noordenbos TW, Schafroth MU Background and purpose Minimally invasive surgery (MIS) for hip replacement is thought to minimize soft tissue damage. We determined the damage caused by 4 different MIS approaches as compared to a conventional lateral transgluteal approach. Methods 5 surgeons each performed a total hip arthroplasty on 5 fresh frozen cadaver hips, using either a MIS anterior, MIS anterolateral, MIS 2-incision, MIS posterior, or lateral transgluteal approach. Postoperatively, the hips were dissected and muscle damage color-stained. We measured proportional muscle damage relative to the midsubstance cross-sectional surface area (MCSA) using computerized color detection. The integrity of external rotator muscles,... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237727 Wed, 01 Dec 2010 00:00:00 +0100 4237727 http://www.medworm.com/index.php?rid=4237726&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110703%26dopt%3DAbstract Authors: Wamper KE, Sierevelt IN, Poolman RW, Bhandari M, Haverkamp D Background and purpose The Harris hip score (HHS), a disease-specific health status scale that is frequently used to measure the outcome of total hip arthroplasty, has never been validated properly. A questionnaire is suitable only when all 5 psychometric properties are of sufficient quality. We questioned the usefulness of the HHS by investigating its content validity. Methods We performed a systematic review based on a literature search in PubMed, Embase, and the Cochrane Library for descriptive studies published in 2007. 54 studies (59 patient groups) met our criteria and were included in the data analysis. To determine the content validity, we calculated the ceiling effect (percentage) for each separate study and... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237726 Wed, 01 Dec 2010 00:00:00 +0100 4237726 http://www.medworm.com/index.php?rid=4237725&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110704%26dopt%3DAbstract Authors: de Wilde LF, Poncet D, Middernacht B, Ekelund A Background and purpose Despite good clinical results with the reverse total shoulder arthroplasty, inferior scapular notching remains a concern. We evaluated 6 different solutions to overcome the problem of scapular notching. Methods An average and a "worst case scenario" shape in A-P view in a 2-D computer model of a scapula was created, using data from 200 "normal" scapulae, so that the position of the glenoid and humeral component could be changed as well as design features such as depth of the polyethylene insert, the size of glenosphere, the position of the center of rotation, and downward glenoid inclination. The model calculated the maximum adduction (notch angle) in the scapular plane when the cup of the humeral component... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237725 Wed, 01 Dec 2010 00:00:00 +0100 4237725 http://www.medworm.com/index.php?rid=4237724&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110705%26dopt%3DAbstract Authors: Devitt BM, Queally JM, Vioreanu M, Butler JS, Murray D, Doran PP, O'Byrne JM Background and purpose Metal ion toxicity both locally and systemically following MoM hip replacements remains a concern. Cobalt ions have been shown to induce secretion of proinflammatory chemokines locally; however, little is known about their effect systemically. We investigated the in vitro effect of cobalt ions on a variety of cell lines by measuring production of the proinflammatory chemokines IL-8 and MCP-1. Method Renal, gastrointestinal, and respiratory epithelium and also neutrophils and monocytes were exposed to cobalt ions at 4, 12, 24, and 48 hours. Results We found that cobalt ions enhanced the secretion of IL-8 and MCP-1 in renal epithelial cells, gastric and colon epithelium, monocytes... Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237724 Wed, 01 Dec 2010 00:00:00 +0100 4237724 http://www.medworm.com/index.php?rid=4237723&cid=s_33497_31_f&fid=33497&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21110706%26dopt%3DAbstract Authors: Watson W, Periasamy K, Meek R PMID: 21110706 [PubMed - in process] (Source: Acta Orthopaedica) Acta Orthopaedica journals http://www.medworm.com/rss/comments.php?id=4237723 Wed, 01 Dec 2010 00:00:00 +0100 4237723