MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Annals of Anatomy' source. Tue, 07 Feb 2012 08:10:08 +0100 http://www.medworm.com/index.php?rid=5623162&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22244384%26dopt%3DAbstract CONCLUSION: Bone level preservation of extraction sockets using Bio-Oss Collagen with implantation is significantly better compared to using Bio-Oss Collagen only and untreated sockets. Implant insertion 8-10weeks after extraction is a suitable time point after socket augmentation. PMID: 22244384 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5623162 Fri, 23 Dec 2011 05:00:00 +0100 5623162 http://www.medworm.com/index.php?rid=5623163&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22244383%26dopt%3DAbstract This study analyses how the AG went through the years of National Socialism. As the society does not possess archival material from that time, the analysis is mainly based on the society proceedings (Verhandlungen der Anatomischen Gesellschaft) published annually after each meeting from 1934 to 1939 and again in 1950. During the period of National Socialism, the AG kept its international status against demands to make it a purely German society. It did not introduce anti-Jewish regulations or the Führer principle into its bylaws. The membership directories reveal that it was at least possible for members whose career was disrupted by Nazi policies to remain on the membership lists throughout the Nazi period. However, in contrast to later assumptions that no persecuted member of the AG was... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5623163 Tue, 20 Dec 2011 05:00:00 +0100 5623163 http://www.medworm.com/index.php?rid=5578514&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22226150%26dopt%3DAbstract CONCLUSIONS: The results indicate the continuous presence of GAL-ergic innervation in the immediate vicinity of the cancer invasion, which may be attributed to increased contraction of the affected part of intestine. PMID: 22226150 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5578514 Sat, 17 Dec 2011 05:00:00 +0100 5578514 http://www.medworm.com/index.php?rid=5578515&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22226149%26dopt%3DAbstract Authors: Rusu MC, Mirancea N, Mănoiu VS, Vâlcu M, Nicolescu MI, Păduraru D Abstract A distinctive stromal cell-type, the telocyte (TC), has recently been described to send specific long prolongations (telopodes) alternating thin segments (podomers) with dilations (podoms). Even though one would expect TCs to be identified in various stromal tissues, there were not yet reported evidence of skin TCs. We aimed to check for the presence of TCs in human skin dermis. Transmission electron microscopy revealed the presence in dermis of TCs projecting specific telopodes. Skin TCs were closely related to or contacting fibroblasts, mast cells, adipocytes, and connective fiber bundles (collagenous and elastic). As it appears, skin TCs exist and are related to other stromal cells. The struct... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5578515 Fri, 16 Dec 2011 05:00:00 +0100 5578515 http://www.medworm.com/index.php?rid=5578518&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22209028%26dopt%3DAbstract Authors: Kürtül I, Hammer N, Rabi S, Saito T, Böhme J, Steinke H Abstract To find an oblique cutting plane of a plastinate, e.g. to cut gamma-nails in the femur, the Block Plastination technique was modified. After CT and MRI examination, the specimens were plastinated with the standard resin mixture E6/E12/E600. Instead of using a box to form a block during the casting and curing stage, we embedded the specimen in a sac made of polyester foil. A polymerized wooden block was attached to the specimen. The sac was wrapped with tape to the embedded specimen with the block. This approach limited the amount of required resin to the inner volume of the plastinate. Then, the plastination sac was put in the incubator for further polymerization and curing. When the foil was removed from ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5578518 Fri, 09 Dec 2011 05:00:00 +0100 5578518 http://www.medworm.com/index.php?rid=5578517&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22209543%26dopt%3DAbstract Authors: Sakamoto Y Abstract The prevertebral muscles are innervated by the cervical ventral rami. However, little information is available on the spatial relationships between the muscles and the supplying branches. This gross anatomical study investigated the prevertebral muscles and the nerves in 26 cadavers to elucidate their spatial interrelationships and the nerve pathways to each muscle. These muscles were characterized by the variations in the vertebral attachments. The scalenus medius was divisible into the dorsal and ventral parts. The scaleni anterior and medius attached to both the anterior and posterior tubercles of the cervical transverse processes. The oblique fibers arising from the transverse processes joined the vertical part of the longus colli. The rectus capiti... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5578517 Thu, 08 Dec 2011 05:00:00 +0100 5578517 http://www.medworm.com/index.php?rid=5578516&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217474%26dopt%3DAbstract Authors: Vlachos A Abstract Synaptopodin (SP) is an actin-binding molecule, which is closely linked with the spine apparatus organelle (SA). Recent experimental evidence suggests that SP containing spines differ in their functional and structural properties from neighboring spines, which do not contain SP. These studies revealed for the first time that SP clusters colocalize with a functional internal source of calcium, which affects synaptic plasticity. Strikingly, SP-cluster associated calcium surges were shown to control synaptic strength in two ways: a ryanodine receptor (RyR) dependent potentiation of synaptic strength was reported, as well as inositol-triphosphate-receptor (IP3R) dependent depression. These results suggested that the SA is an important component of the molecu... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5578516 Sat, 03 Dec 2011 05:00:00 +0100 5578516 http://www.medworm.com/index.php?rid=5550366&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22196998%26dopt%3DAbstract CONCLUSIONS: Small numbers of investigated specimens can lead to confounding results. The classification used has to be precisely determined. Both classifications need to be known to interpret results correctly. A repetition of investigation might be performed to confirm results. PMID: 22196998 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5550366 Sat, 03 Dec 2011 05:00:00 +0100 5550366 http://www.medworm.com/index.php?rid=5550365&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22197495%26dopt%3DAbstract Authors: Alibardi L Abstract The participation of involucrin in the cornification of the human hair has been studied by light and electron microscopy immunohistochemistry. Immunoreactivity for involucrin is absent in keratinized cuticle and cortical cells although some immunolabeling is observed in the corneous membrane of internal cortical cells surrounding the hair medulla. Conversely, immunolabeling for involucrin is present in the cytoplasm of keratinizing cells of the medulla and inner root sheath. During the maturation and final cornification of medullary and inner root sheath cells the immunolabeling for involucrin tends to concentrate in the peripheral cytoplasm and along the cornified cell plasma membrane in both medullary and inner root sheath cells, a pattern similar to ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5550365 Sat, 03 Dec 2011 05:00:00 +0100 5550365 http://www.medworm.com/index.php?rid=5550364&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22197496%26dopt%3DAbstract In this study, PEP 19-immunoreactivity (ir) was examined in the rat trigeminal sensory nuclei. Numerous PEP 19-immunoreactive (ir) neurons were detected in the medullary dorsal horn (MDH) and rostral parts of the trigeminal sensory nuclei (subnuclei interpolaris and oralis, and nucleus principalis). The mean numbers±S.D. per section of PEP 19-ir neurons were 104.2±30.4 in the MDH, 137.8±39.5 in the subnucleus interpolaris, 129.2±46.9 in the subnucleus oralis and 157.2±34.1 in the nucleus principalis. In the MDH, small to medium-sized PEP 19-ir neurons were abundant within superficial laminae. PEP 19-ir neurons with various cell body sizes were also distributed in the rostral parts of the trigeminal sensory nuclei. A double immunofluorescence analysis also demonstrated that many PEP 19... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5550364 Sat, 03 Dec 2011 05:00:00 +0100 5550364 http://www.medworm.com/index.php?rid=5513700&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22169595%26dopt%3DAbstract Authors: Kirsanow K, Burger J Abstract The contribution of palaeogenetic data to the study of various aspects of hominin biology and evolution has been significant, and has the potential to increase substantially with the widespread implementation of next generation sequencing techniques. Here we discuss the present state-of-the-art of ancient human DNA analysis and the characteristics of hominin aDNA that make sequence validation particularly complex. A brief overview of the development of anthropological palaeogenetic analysis is given to illustrate the technical challenges motivating recent technological advancements. PMID: 22169595 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5513700 Fri, 18 Nov 2011 05:00:00 +0100 5513700 http://www.medworm.com/index.php?rid=5513702&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22154005%26dopt%3DAbstract Authors: Svensson EM, Telldahl Y, Sjöling E, Sundkvist A, Hulth H, Sjøvold T, Götherström A Abstract Domestication of animals and plants marked a turning point in human prehistory. To date archaeology, archaeozoology and genetics have shed light on when and where all of our major livestock species were domesticated. Phenotypic changes associated with domestication have occurred in all farm animals. Coat colour is one of the traits that have been subjected to the strongest human selection throughout history. Here we use genotyping of coat colour SNPs in horses to investigate whether there were any regional differences or preferences for specific colours associated with specific cultural traditions in Iron Age Sweden. We do this by identifying the sex and coat colour of horses sa... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5513702 Thu, 17 Nov 2011 05:00:00 +0100 5513702 http://www.medworm.com/index.php?rid=5513701&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22154270%26dopt%3DAbstract In conclusion, both approaches produced reliable results for most allelic patterns. But an indel of 11bp (ASIP) could not be detected in the KASPar approach and produced problems in the pyrosequencing method (70% success rate). In such cases, we recommend checking allelic distribution using a gel approach or capillary sequencing. Overall, in comparison with the traditional mode of ancient DNA investigations (PCR, cloning, capillary sequencing), both approaches are superior for SNP analyses especially of large sample sets. PMID: 22154270 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5513701 Thu, 03 Nov 2011 04:00:00 +0100 5513701 http://www.medworm.com/index.php?rid=5421286&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22074679%26dopt%3DAbstract This study indicates distinct subset- and cytokine-specific in vivo effects induced by an NPY Y(2) receptor specific treatment after a short-term LPS challenge. PMID: 22074679 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421286 Fri, 21 Oct 2011 04:00:00 +0100 5421286 http://www.medworm.com/index.php?rid=5421290&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22055939%26dopt%3DAbstract In this study we analysed the expression pattern of ADAM17 during mouse eye development. ADAM17 expression in adult retina was examined using the reverse transcription-polymerase chain reaction (RT-PCR) and verification of the RT-PCR products by DNA sequencing. Immunohistochemistry was performed to evaluate the ADAM17 expression pattern in mouse eyes at developmental stages of embryonic day (E) 12, E14, E16, E18, postnatal day (P) 0, P1, P4, P7, P14, P 30 and P175 (adult). We detected ADAM17 mRNA in adult retina tissue. ADAM17 protein was expressed in non-pigmented ciliary epithelial cells and in retinal vessels from P7 onwards during eye development. In corneal epithelial cells and endothelium, ADAM17 protein was present from P14 onwards. Although, mice in which the functional ADAM17 gene... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421290 Mon, 17 Oct 2011 04:00:00 +0100 5421290 http://www.medworm.com/index.php?rid=5421289&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22056295%26dopt%3DAbstract Authors: Heinemann F, Hasan I, Kunert-Keil C, Götz W, Gedrange T, Spassov A, Schweppe J, Gredes T Abstract Over the past decade, coinciding with the appearance of a number of new ultrasonic surgical devices, there has been a marked increase in interest in the use of ultrasound in oral surgery and implantology as alternative osteotomy method. The aim of this study was the comparison of the effect of osteotomies performed using ultrasonic surgery (Piezosurgery(®)), sonic surgery SONICflex(®) and the conventional bur method on the heat generation within the bone underneath the osteotomy and light-microscopy observations of the bone at different cutting positions in porcine mandibular segments. It was found that the average heat generated by SONICflex(®) sonic device was close to t... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421289 Mon, 17 Oct 2011 04:00:00 +0100 5421289 http://www.medworm.com/index.php?rid=5421292&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22055937%26dopt%3DAbstract In conclusion, BONITmatrix(®) and OSSA NOVA stimulate the expression of growth factor IGF1, but only the granular dosage form is able to stimulate osteoblast differentiation. PMID: 22055937 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421292 Fri, 14 Oct 2011 04:00:00 +0100 5421292 http://www.medworm.com/index.php?rid=5421291&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22055938%26dopt%3DAbstract Authors: Götz W, Reichert C, Canullo L, Jäger A, Heinemann F Abstract Similar to osteogenesis and bone repair, the healing and osteogenesis of bone substitutes depend on the osteogenesis-angiogenesis interplay which is controlled by different factors, including VEGF or by hypoxia. A brief review of the process of bone substitute angiogenesis is presented and illustrated by our histological and immunohistochemical findings taken from human biopsies after augmentation with a nanocrystalline synthetic bone substitute. PMID: 22055938 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421291 Fri, 14 Oct 2011 04:00:00 +0100 5421291 http://www.medworm.com/index.php?rid=5421288&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22056339%26dopt%3DAbstract Authors: Jäger K, Nielitz A, Garreis F, Sel S, Nave H, Paulsen FP Abstract To analyse the hypothesis as to whether there is a functional relationship between human cationic amino acid transporters (hCATs, y(+) transporter, the main transporter of l-arginine and l-lysine) and human β-defensin (important components of immune function) production on the ocular surface, arginase and nitrate monoxide synthase (NOS), enzymes that compete for l-arginine, were inhibited by norNOHA (N(omega)-hydroxy-nor-l-arginine) and/or L-NAME (NG-nitro-l-arginine methyl ester) in cultured human corneal epithelial cells. In addition, the transport activity of hCAT proteins was inhibited or activated through α-tocopherol or PMA (phorbol myristate acetate), respectively. Concentrations of the human induc... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421288 Fri, 14 Oct 2011 04:00:00 +0100 5421288 http://www.medworm.com/index.php?rid=5421287&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22074678%26dopt%3DAbstract Authors: Boldt J, Knapp W, Proff P, Rottner K, Richter EJ Abstract In vivo measurement of the mobility of teeth under physiological loading has been subject of research for years. Comparing the deflection under load of dental implants with teeth provides valuable input for designing restorations spanning both teeth and implants. Physiological force rise time of about 50-100ms and displacement of 10-100μm requires high spatial and temporal resolution of the measurement set-up. Using an optical system attached to the teeth/implants to be measured and a light source attached to a point of reference, displacement of teeth and implants under axial and lateral loading was measured on a series of volunteers. Axial displacement of teeth shows strong time dependence consistent with (hydrau... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421287 Fri, 14 Oct 2011 04:00:00 +0100 5421287 http://www.medworm.com/index.php?rid=5421285&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22079779%26dopt%3DAbstract Authors: Kubein-Meesenburg D, Nägerl H, Fialka-Fricke J, Hahn W, Weber S, Ihlow D, Hönig J, Hansen C, Fanghänel J, Thieme KM Abstract Due to its complexity, there is currently an incomplete understanding of temporomandibular joint (TMJ) function, especially in relation to the morphological interplay of the condyle and the disc as well as the disc, the Os temporale and the lateral pterygoid muscle. This also holds true for synovial flow and synovial pumps, the existence of which we postulate and for which we present a theory of their mechanism. In view of the complexity of mandibular movements and the morphology and function of the TMJ, we need to know how precisely a reconstruction of the TMJ, if necessary, must be adapted to nature. An analysis of the morphology of the function... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5421285 Fri, 14 Oct 2011 04:00:00 +0100 5421285 http://www.medworm.com/index.php?rid=5380020&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22051238%26dopt%3DAbstract This study was designed to investigate the effect of strontium on human PDL cells in vitro. Strontium is used to treat osteoporosis because of its bone formation promoting effect on osteoblast cells. This investigation presents evidence that strontium promotes PDL cell proliferation. Simultaneously, strontium suppresses the expression of the inflammation-promoting cytokine IL-6. The observed effect of strontium on PDL cells supports its use it in guided dental tissue regeneration. PMID: 22051238 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5380020 Fri, 14 Oct 2011 04:00:00 +0100 5380020 http://www.medworm.com/index.php?rid=5380021&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22041664%26dopt%3DAbstract Authors: Lolis E, Panagouli E, Venieratos D Abstract The surgical anatomy (geometrical features, metric relations, and drainage pattern) of the ascending lumbar vein (ALV) and iliolumbar vein (ILV) is clinically important. Notwithstanding, the available literature comprises but a small number of studies and a limited number of specimens involved. The present study constitutes a detailed description and classification of the drainage pattern of both these veins. The detailed anatomy of ALV and ILV was examined in both sides in 59 embalmed adult human cadavers of Caucasian origin. Cases with anatomical variations (9 cadavers) of the inferior vena cava (IVC), common iliac vein (CIV), external iliac vein (EIV) and internal iliac vein (IIV) were excluded from subsequent study and analys... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5380021 Thu, 13 Oct 2011 04:00:00 +0100 5380021 http://www.medworm.com/index.php?rid=5380019&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22051239%26dopt%3DAbstract Authors: Kirkeby S, Mikkelsen HB, Vorum H Abstract The conjunctiva of the eyelid is coated by secretion products from the lacrimal and eyelid glands, and by mucins produced by conjunctival goblet cells, which together form a glycoprotein-rich layer that lubricates and protects the surface of the eye. However, these ocular carbohydrates may also act as adhesives for viruses and bacteria and thereby facilitate their colonization. This paper provides histochemical demonstration of the in situ localization of such carbohydrate receptors in the form of sialylated glycans and mucins in the lacrimal and eyelid glands and conjunctiva from both humans and pigs. The pig is included in this study because viruses of swine origin may be capable of transmission to humans. We found that the human... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5380019 Thu, 13 Oct 2011 04:00:00 +0100 5380019 http://www.medworm.com/index.php?rid=5380022&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22035706%26dopt%3DAbstract Authors: Behr M, Hahnel S, Faltermeier A, Bürgers R, Kolbeck C, Handel G, Proff P Abstract Bruxism is characterized by non-functional contact of mandibular and maxillary teeth resulting in clenching or grating of teeth. Theories on factors causing bruxism are a matter of controversy in current literature. The dental profession has predominantly viewed peripheral local morphological disorders, such as malocclusion, as the cause of clenching and gnashing. This etiological model is based on the theory that occlusal maladjustment results in reduced masticatory muscle tone. In the absence of occlusal equilibration, motor neuron activity of masticatory muscles is triggered by periodontal receptors. The second theory assumes that central disturbances in the area of the basal ganglia are ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5380022 Wed, 05 Oct 2011 04:00:00 +0100 5380022 http://www.medworm.com/index.php?rid=5361321&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21996707%26dopt%3DAbstract In this study, the biographies of 462 Scholars of Anatomy were examined. 414 were members of the Anatomische Gesellschaft (Anatomical Society). Eighty-six persons (80 men, 6 women) were identified whose anatomical careers were disrupted by National Socialist policies. Sixty-two of them were members of the Anatomical Society. Their subsequent fate was dependent on the stage of the scholars' careers, their field of expertise, reason for dismissal (i.e. so-called Jewish descent or political dissent), nationality, country of residence or exile. Forty-three scholars emigrated, of whom 6 returned to positions in Germany and Austria after the war. Twenty-one remained in their home countries, of whom 17 were later reinstated in their positions. Twelve scholars were imprisoned, and 5 died in concen... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5361321 Thu, 22 Sep 2011 04:00:00 +0100 5361321 http://www.medworm.com/index.php?rid=5297776&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21978794%26dopt%3DAbstract Authors: Schultka R, Viebig M Abstract In the period from 1933 to 1945 the Anatomical Institute in Halle (Saale) received bodies of persons, among them politically persecuted women and men, who had been sentenced to death and executed. In this article, we attempt to answer two important questions: The bodies of those executed were used in anatomical education, anatomical research, and in preparations of anatomical specimens to be added to the anatomical collection. There are eight macroscopic preparations which can definitely be associated with the bodies of people executed during the Nazi regime. Trial by jury sentenced those people to the maximum penalty because of the severity of their criminal acts. Up to now we have found no evidence that specimens of the anatomical collection... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5297776 Fri, 16 Sep 2011 04:00:00 +0100 5297776 http://www.medworm.com/index.php?rid=5281288&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21955673%26dopt%3DAbstract This study presents a morphometric developmental analysis of bovine kidneys and a demonstration of intrarenal arterial vascularization in the prenatal period. A total of 40 Holstein bovine fetuses constituted the material of the study. The fetuses were divided into three groups, according to the gestational stages they belonged to early, mid- and late stages, such that each group comprised 10 fetuses. Sixty kidneys and their renal arteries were evaluated using morphometric measurements. Furthermore, 10 bovine fetuses were injected with cast solution to demonstrate the intrarenal arteries. Data obtained in the present study were statistically analyzed. Although the right and left kidneys did not significantly differ from each other, significant differences existed between the different gest... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5281288 Fri, 16 Sep 2011 04:00:00 +0100 5281288 http://www.medworm.com/index.php?rid=5281287&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21955674%26dopt%3DAbstract Authors: Kano M, Shimizu Y, Suzuki Y, Furukawa Y, Ishida H, Oikawa M, Kanetaka H, Ichikawa H, Suzuki T Abstract The distribution of pituitary adenylatecyclase-activating polypeptide-immunoreactive (PACAP-IR) nerve fibers was studied in the rat epiglottis and pharynx. PACAP-IR nerve fibers were located beneath the mucous epithelium, and occasionally penetrated the epithelium. These nerve fibers were abundant on the laryngeal side of the epiglottis and in the dorsal and lateral border region between naso-oral and laryngeal parts of the pharynx. PACAP-IR nerve fibers were also detected in taste buds within the epiglottis and pharynx. In addition, many PACAP-IR nerve fibers were found around acinar cells and blood vessels. The double immunofluorescence method demonstrated that distribu... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5281287 Wed, 14 Sep 2011 04:00:00 +0100 5281287 http://www.medworm.com/index.php?rid=5219206&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21889322%26dopt%3DAbstract In this study on 34 examined medieval Korean skeletons, 11 (32.3%) showed perfectly matching results for the three methods of sex determination. In the cases in which the cultural and anatomical findings were discordant, the amelogenin assay corroborated either the former or the latter. Although we must admit the relatively limited role of aDNA analysis, when only very small amounts of amplifiable DNA remain, we believe that the amelogenin assay can be very meaningful to Korean anatomists when employed in adjunct to conventional anatomically or culturally based sex determination. PMID: 21889322 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5219206 Sat, 30 Jul 2011 04:00:00 +0100 5219206 http://www.medworm.com/index.php?rid=5157447&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21855309%26dopt%3DAbstract Authors: Campos PF, Craig OE, Turner-Walker G, Peacock E, Willerslev E, Gilbert MT Abstract Despite the widespread use of bones in ancient DNA (aDNA) studies, relatively little concrete information exists in regard to how the DNA in mineralised collagen degrades, or where it survives in the material's architecture. While, at the macrostructural level, physical exclusion of microbes and other external contaminants may be an important feature, and, at the ultrastructural level, the adsorption of DNA to hydroxyapatite and/or binding of DNA to Type I collagen may stabilise the DNA, the relative contribution of each, and what other factors may be relevant, are unclear. There is considerable variation in the quality of DNA retrieved from bones and teeth. This is in part due to various en... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5157447 Fri, 29 Jul 2011 23:00:00 +0100 5157447 http://www.medworm.com/index.php?rid=5103894&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21802916%26dopt%3DAbstract CONCLUSIONS: c-kit+TNs were objectified in humans and strongly presumed to be nociceptive. TNs envelopes mostly consist of SGCs, but are also combined with ICLCs/telocytes. PMID: 21802916 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5103894 Sun, 17 Jul 2011 23:00:00 +0100 5103894 http://www.medworm.com/index.php?rid=5103896&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21798733%26dopt%3DAbstract Authors: Fan SJ, Jiang H, Yang LJ, Liu X, Song J, Pan F This preliminary study aims to explore how adrenergic agents modulate stress response and affect stress-induced behavioral and brain changes in rodents. A total of 40 adult male Wistar rats were subjected to chronic unpredictable mild stress (CUMS) and randomly divided into five groups. At 30min before daily stress exposure, the rats were intraperitoneally injected with phentolamine (5mg/kg), noradrenalin (1.0mg/kg), propranolol (10mg/kg), isoproterenol (0.05mg/kg) or saline, respectively. Another 8 rats served as normal control and received daily saline injection without stress exposure. Open-field behaviors were tested at 1 day after the end of the 21 days of stress exposure. Blood samples were collected for serum corticosterone... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5103896 Thu, 07 Jul 2011 23:00:00 +0100 5103896 http://www.medworm.com/index.php?rid=5103895&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21802915%26dopt%3DAbstract In conclusion, 8mm defects can be considered as critical size defects and only FDBA showed mature lamellar bone at 90 days. PMID: 21802915 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5103895 Thu, 07 Jul 2011 23:00:00 +0100 5103895 http://www.medworm.com/index.php?rid=5103893&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21803554%26dopt%3DAbstract Authors: Toni R, Tampieri A, Zini N, Strusi V, Sandri M, Dallatana D, Spaletta G, Bassoli E, Gatto A, Ferrari A, Martin I Ex situ bioengineering is one of the most promising perspectives in the field of regenerative medicine allowing for organ reconstruction outside the living body; i.e. on the laboratory bench. A number of hollow viscera of the cardiovascular, respiratory, genitourinary, and digestive systems have been successfully bioengineered ex situ, exploiting biocompatible scaffolds with a 3D morphology that recapitulates that of the native organ (organomorphic scaffold). In contrast, bioengineering of entire soft tissue organs and, in particular endocrine glands still remains a substantial challenge. Primary reasons are that no organomorphic scaffolding for endocrine viscera ha... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=5103893 Thu, 07 Jul 2011 23:00:00 +0100 5103893 http://www.medworm.com/index.php?rid=4961603&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21684729%26dopt%3DAbstract Authors: Raikos A, Paraskevas GK, Yusuf F, Kordali P, Meditskou S, Al-Haj A, Brand-Saberi B Hyperostosis frontalis interna is a morphological pattern characterized by single or multiple bony nodules situated on the inner lamina of the frontal bone. It is seldom found in males, but it is a common phenomenon among post-menopausal females in modern societies but relatively rare in antiquity. The etiopathogenesis of the trait is a matter of debate and ranges from genetic predisposition to epigenetic, while endocrine disturbances, aging, and dietary factors are also listed among the causes. We studied the frequency, characteristic features, and etiopathogenesis of the disease in recent cadaveric and dry skull specimens. The frequency of hyperostosis frontalis interna in cadavers and dry sku... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4961603 Thu, 26 May 2011 23:00:00 +0100 4961603 http://www.medworm.com/index.php?rid=4961604&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21664112%26dopt%3DAbstract This study was performed on 31 pregnant mice that were divided into six groups. The control group received normal saline and test groups received CP (20mg/kg), carvedilol (5mg/kg), melatonin (10mg/kg), CP (20mg/kg) pluscarvedilol (5mg/kg) and CP (20mg/kg) plus melatonin (10mg/kg) intraperitoneally on the 10th day of gestation, respectively. Fetuses were collected on the 19th day of gestation and after determination of weight and length; they were stained by Alizarin red-Alcian blue method. Cleft palate, spina bifida and exencephalyincidence were 62.79%, 62.79% and 30.23% in fetuses of mice that received only CP. Cleft palate,spina bifida, exencephaly, and incidence were 45.45%, 9.09% and 0% in group which received CP plus carvedilol (5mg/kg), respectively.However, cleft palate, spina bifid... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4961604 Tue, 17 May 2011 23:00:00 +0100 4961604 http://www.medworm.com/index.php?rid=4912698&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21646004%26dopt%3DAbstract In conclusion, anterior edge-to-edge-bite/crossbite is connected to a reduced eminence height and deep bite without gingival contact with an increased ratio between eminence height and postglenoid process height. Therefore the condylar path in the anterior edge-to-edge bite and crossbite cases can be interpreted to be reduced and in the deep bite cases without gingival contact to be steepened. PMID: 21646004 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4912698 Mon, 16 May 2011 23:00:00 +0100 4912698 http://www.medworm.com/index.php?rid=4961605&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21652193%26dopt%3DAbstract Authors: Foote AD, Hofreiter M, Morin PA Marine mammals have long generation times and broad, difficult to sample distributions, which makes inferring evolutionary and demographic changes using field studies of extant populations challenging. However, molecular analyses from sub-fossil or historical materials of marine mammals such as bone, tooth, baleen, skin, fur, whiskers and scrimshaw using ancient DNA (aDNA) approaches provide an opportunity for investigating such changes over evolutionary and ecological timescales. Here, we review the application of aDNA techniques to the study of marine mammals. Most of the studies have focused on detecting changes in genetic diversity following periods of exploitation and environmental change. To date, these studies have shown that even small s... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4961605 Thu, 12 May 2011 23:00:00 +0100 4961605 http://www.medworm.com/index.php?rid=4912735&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21641192%26dopt%3DAbstract Authors: Hofreiter M PMID: 21641192 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4912735 Thu, 12 May 2011 23:00:00 +0100 4912735 http://www.medworm.com/index.php?rid=4912709&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21641784%26dopt%3DAbstract This article reviews the advantages, problems, and failures of ancient microbiological research. PMID: 21641784 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4912709 Tue, 10 May 2011 23:00:00 +0100 4912709 http://www.medworm.com/index.php?rid=4865939&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21600746%26dopt%3DAbstract Authors: Nógrádi A, Pajer K, Márton G Spinal cord injury or disease result in the loss of critical numbers of spinal motoneurons and consequentially, in severe functional impairment. The most successful way to replace missing motoneurons is the use of embryonic postmitotic motoneuron grafts. This method may also at least partially restore integrity of the injured spinal cord. It has been shown that grafted motoneurons survive, differentiate and integrate into the host cord and many of them are able to reinnervate the denervated muscles. If grafted motoneurons are provided with a conduit (e.g. reimplanted ventral root) the grafted cells are able to extend their axons along the entire length of the peripheral nerves and reach the hind or forelimb muscles and to restore limb locomotion... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4865939 Fri, 29 Apr 2011 23:00:00 +0100 4865939 http://www.medworm.com/index.php?rid=4865940&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21596537%26dopt%3DAbstract Authors: Allentoft ME, Rawlence NJ The moa (Aves: Dinornithiformes) of New Zealand represent one of the extinct iconic taxa that define the field of ancient DNA (aDNA), and after almost two decades of genetic scrutiny of bones, feathers, coprolites, mummified tissue, eggshell, and sediments, our knowledge of these prehistoric giants has increased significantly. Thanks to molecular and morphological-based research, the insights that have been obtained into moa phylogenetics, phylogeography, and palaeobiology exceeds that of any other extinct taxon. This review documents the strengths of applying a multidisciplinary approach when studying extinct taxa but also shows that cross-disciplinary controversies still remain at the most fundamental levels, with highly conflicting interpretations ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4865940 Wed, 27 Apr 2011 23:00:00 +0100 4865940 http://www.medworm.com/index.php?rid=4865941&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21561749%26dopt%3DAbstract CONCLUSION: The vaginal descent is classically regarded as a relative topographical change, but it is likely to be a result of elongation of the proximal urethra in the superior side of the vaginal merging. Conversely, the distal urethra is likely to be incorporated into the vaginal vestibulum by 15 weeks. During these processes, most of the female external sphincter seems to be expelled from the original anterior position into the vestibular wall as the urethrovaginal sphincter. The adult female urethra seems to correspond to the male prostatic urethra superior to the prostatic colliculus. PMID: 21561749 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4865941 Tue, 12 Apr 2011 23:00:00 +0100 4865941 http://www.medworm.com/index.php?rid=4813575&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21531123%26dopt%3DAbstract Authors: Palmer SA, Smith O, Allaby RG Recent years have seen a broadening range of studies undertaken in the field of plant archaeogenetics as the field has entered a new stage of maturity. There has been a movement towards a more functional understanding of plant evolution that has been facilitated by sequencing technologies and increasingly powerful genomic annotation. Studies have progressed to consideration of genes of pertinent function, metagenomics and investigation of the genetic basis of domestication traits coupled with human agricultural selection. Recent applications of high-throughput sequencing have facilitated archaeogenomic investigations and allowed increasingly fragmented DNA to be retrieved and characterised. While these developments are leading to the selective res... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813575 Fri, 08 Apr 2011 23:00:00 +0100 4813575 http://www.medworm.com/index.php?rid=4813578&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21530207%26dopt%3DAbstract Ann Anat. 2011 Apr 8; Authors: Angelov D, Klimaschewski L PMID: 21530207 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813578 Thu, 07 Apr 2011 23:00:00 +0100 4813578 http://www.medworm.com/index.php?rid=4813576&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21530208%26dopt%3DAbstract Authors: Ralte S, Khatri K, Nagar M The present study was conducted to histomorphometrically evaluate the effects of short-term administration of zoledronate, a third generation bisphosphonate, on the metaphysis of the proximal end of tibia in twenty day old male albino rats. Zoledronate (2.8μg/kg body weight), was daily given subcutaneously for eleven days. The animals were sacrificed; tibiae were dissected out and decalcified in EDTA. Seven micron thick, serial longitudinal paraffin sections were stained with haematoxylin and eosin and examined under a Zeiss light microscope and Image Pro-Express Analyzer. In zoledronate treated rats, a significant increase (p<0.05) in the number of osteoclasts was observed both in the regions of primary spongiosa (zoledronate treated: 6.41±0.30... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813576 Tue, 05 Apr 2011 23:00:00 +0100 4813576 http://www.medworm.com/index.php?rid=4813580&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21530205%26dopt%3DAbstract Authors: Bengtsson CF, Olsen ME, Brandt LO, Bertelsen MF, Willerslev E, Tobin DJ, Wilson AS, Gilbert MT Keratinous tissues such as nail, hair, horn, scales and feather have been used as a source of DNA for over 20 years. Particular benefits of such tissues include the ease with which they can be sampled, the relative stability of DNA in such tissues once sampled, and, in the context of ancient genetic analyses, the fact that sampling generally causes minimal visual damage to valuable specimens. Even when freshly sampled, however, the DNA quantity and quality in the fully keratinized parts of such tissues is extremely poor in comparison to other tissues such as blood and muscle - although little systematic research has been undertaken to characterize how such degradation may relate to s... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813580 Mon, 04 Apr 2011 23:00:00 +0100 4813580 http://www.medworm.com/index.php?rid=4813574&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21550221%26dopt%3DAbstract Authors: Karabekir HS, Gocmen-Mas N, Edizer M, Ertekin T, Yazici C, Atamturk D The use of technology in the treatment of degenerative spinal diseases has undergone rapid clinical and scientific development. It has been extensively studied in combination with various techniques for spinal stabilization from both the anterior and posterior approach. Minimally invasive and instrumental approach via posterior fixation is increasingly being used for the treatment of adult degenerative disc disease, stenosis, and deformity of the lumbar vertebrae. Posterior access to the lumbar disc spaces for posterolateral fusion scan has been technically challenging, frequently requiring the use of an approach surgery for adequate exposure. For successful surgery and suitable instrumental design, adequate... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813574 Fri, 01 Apr 2011 23:00:00 +0100 4813574 http://www.medworm.com/index.php?rid=4813590&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459564%26dopt%3DAbstract Authors: Höltje M, Just I, Ahnert-Hilger G Bacterial C3 exoenzymes are widely used tools to investigate cellular events influenced by small GTPases of the Rho subfamily. In this respect they have gained increasing interest in addressing questions dealing with the neuronal morphogenic program during development and after lesion of the mature nervous system. Since central neurons display only very limited capacity to re-grow their axons after injury, successful strategies to improve regeneration are much sought-after. For a long time exclusively considered to be Rho-inhibiting exoenzymes, there is now accumulating evidence that C3 proteins of clostridial sources exhibit their often beneficial effects on neurite outgrowth by other means than ADP-ribosylation. The current review will outl... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813590 Thu, 31 Mar 2011 23:00:00 +0100 4813590 http://www.medworm.com/index.php?rid=4813588&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21507617%26dopt%3DAbstract How to judge a book by its cover? How useful are bibliometric indices for the evaluation of "scientific quality" or "scientific productivity"? Ann Anat. 2011 Apr 1; Authors: von Bohlen Und Halbach O How to pre-select the most promising candidates for an open position out of several applications? One of the possibilities is to check the personal bibliometric indices of these candidates by looking into appropriate databases. In these databases the number of publications, the total number of citations, the average number of citations per paper and the h-index are easy to find. Thus, it is easy to use these parameters for a pre-election. First, the particular values for the several bibliometric indicators could be retrieved for scientists working in the field of Anatomy & Cell ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813588 Thu, 31 Mar 2011 23:00:00 +0100 4813588 http://www.medworm.com/index.php?rid=4813589&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21501956%26dopt%3DAbstract Authors: Schlumbaum A, van Glabeke S, Roldan-Ruiz I Wild apples (Malus sp.) have been a major food source in the northern Alpine region since prehistory and their use is well understood. The onset of deliberate fruit tree growing in the area is, however, less clear. It is generally assumed that horticulture was practised in Roman times, but it might be even earlier. In the archaeological record seed testa and pericarp remains are particularly frequent at sites with waterlogged preservation such as lakeshore settlements or wells, pits and ditches, but the distinction between wild and domestic plants is not morphologically possible. With waterlogged remains being one main source of information about past fruit cultivation, we have tested the feasibility of analysing ancient DNA from wate... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813589 Wed, 30 Mar 2011 23:00:00 +0100 4813589 http://www.medworm.com/index.php?rid=4813587&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21511447%26dopt%3DAbstract In conclusion, Thiel embalmed tendons did not faithfully represent the biomechanical characteristics of fresh frozen tendons. PMID: 21511447 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813587 Wed, 30 Mar 2011 23:00:00 +0100 4813587 http://www.medworm.com/index.php?rid=4813586&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21514120%26dopt%3DAbstract Authors: Knapp M, Clarke AC, Horsburgh KA, Matisoo-Smith EA With the introduction of next generation high throughput sequencing in 2005 and the resulting revolution in genetics, ancient DNA research has rapidly developed from an interesting but marginal field within evolutionary biology into one that can contribute significantly to our understanding of evolution in general and the development of our own species in particular. While the amount of sequence data available from ancient human, other animal and plant remains has increased dramatically over the past five years, some key limitations of ancient DNA research remain. Most notably, reduction of contamination and the authentication of results are of utmost importance. A number of studies have addressed different aspects of sampling... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813586 Wed, 30 Mar 2011 23:00:00 +0100 4813586 http://www.medworm.com/index.php?rid=4813585&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21514122%26dopt%3DAbstract Authors: Rosenkranz K, Meier C Cell transplantation has been proposed as a potential approach to the treatment of neurological disorders. One cell population of interest consists of human umbilical cord blood (hUCB) cells, which have previously been shown to be useful for reparative medicine in haematological diseases. However, hUCB cells are also capable of differentiating into various non-haematopoietic cells, including those of the neural lineage. Moreover, hUCB cells can secrete numerous neurotrophic factors and modulate immune function and inflammatory reaction. Several studies on animal models of ischemic brain injury have demonstrated the potential of hUCB cells to minimize damage and promote recovery after ischemic brain injury.This review focuses on the treatment of both strok... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813585 Wed, 30 Mar 2011 23:00:00 +0100 4813585 http://www.medworm.com/index.php?rid=4813579&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21530206%26dopt%3DAbstract In this study we have evaluated the morphology of 3rd trimester human fetal temporomandibular (TMJ) specimens in order to determine the pattern of the vascular morphology associated with the layers and vascular canals (VCs) of the developing condyle (covering layers and condyle proper). Eleven human fetuses of 27-38cm crown-rump length were used for histological (hematoxylin-eosin, Van Gieson stain) and immunohistochemical evaluation (antibodies for bcl2 and CD34) and another two of 24 and 31cm, for TMJ microvasculature studies after black ink injections. With increasing fetal age, the intermediate loose lamina (LL) of the condylar proliferative layer evolves from a vascular-mesenchymal to a fibrillar pattern, via a transitory stage of a clear space that may be misdiagnosed as lower joint ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813579 Wed, 30 Mar 2011 23:00:00 +0100 4813579 http://www.medworm.com/index.php?rid=4813595&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21454060%26dopt%3DAbstract CONCLUSION: On the basis of its history, we suggest that the term "Haller's cell" should be restricted to the most inferior infraorbital ethmoid cell, that nearest the ostium of the maxillary sinus. PMID: 21454060 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813595 Tue, 29 Mar 2011 23:00:00 +0100 4813595 http://www.medworm.com/index.php?rid=4813594&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21458249%26dopt%3DAbstract Authors: Dubový P Wallerian degeneration is a cascade of stereotypical events in reaction to injury of nerve fibres. These events consist of cellular and molecular alterations, including macrophage invasion, activation of Schwann cells, as well as neurotrophin and cytokine upregulation. This review focuses on cellular and molecular changes distal to various types of peripheral nerve injury which simultaneously contribute to axonal regeneration and neuropathic pain induction. In addition to the stereotypical events of Wallerian degeneration, various types of nerve damage provide different conditions for both axonal regeneration and neuropathic pain induction. Wallerian degeneration of injured peripheral nerve is associated with an inflammatory response including rapid upregulation of t... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813594 Tue, 29 Mar 2011 23:00:00 +0100 4813594 http://www.medworm.com/index.php?rid=4813593&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21458250%26dopt%3DAbstract CONCLUSIONS: Cytokeratin-positive hepatic progenitor cells are likely to exist along the hilar portal pedicle even in adults. These hilar marginal hepatocytes seem to be derived not from the fetal ductal plate, but from the liver parenchyma. PMID: 21458250 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813593 Tue, 29 Mar 2011 23:00:00 +0100 4813593 http://www.medworm.com/index.php?rid=4813591&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21458251%26dopt%3DAbstract Authors: Ozsoy U, Hizay A, Demirel BM, Ozsoy O, Bilmen Sarikcioglu S, Turhan M, Sarikcioglu L Nerve repair after facial nerve injury provides neural input to the distal facial nerve and facial musculature via a variety of motor nerves such as hypoglossal, spinal accessory, masseteric branch of the trigeminal nerve and motor branches of the cervical plexus. The most commonly used procedure is the hypoglossal-facial nerve transfer. This cross-nerve paradigm is a unique nerve repair method as one motor nerve takes over the function of another motor nerve. The hypoglossal-facial nerve repair was reviewed by means of history, terminology, technical variations, and its capacity for recovery of function. PMID: 21458251 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813591 Tue, 29 Mar 2011 23:00:00 +0100 4813591 http://www.medworm.com/index.php?rid=4813598&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21454059%26dopt%3DAbstract We examined post mortem human retinas for the localization of a biomarker of lipid peroxidation (4-hydroxy 2-nonenal, 4-HNE) by immunohistochemistry. We procured human eyes from donors (N=11; age: 45-91 years; post mortem delay: 1-3h), who had no history of ocular diseases. They were fixed in 4% paraformaldehyde and the retinas cryosectioned and labeled against anti-4-HNE employing the immunoperoxidase method. Compared to the lower age group (45-56 years), in the advanced age group (67-91 years), immunoreactivity (IR) to 4-HNE was prominent in peripheral Müller cell end-feet, select cells in the inner nuclear layer and in outer fibers located in the macular fiber layer of Henle. Colocalization with glutamine synthetase revealed that the 4-HNE positive profiles in the inner nuclear layer w... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813598 Mon, 28 Mar 2011 23:00:00 +0100 4813598 http://www.medworm.com/index.php?rid=4813600&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21444196%26dopt%3DAbstract Authors: Oh CS, Lee SY, Lee IS, Kim YS, Koh KS, Shin DH In our previous CT and post-factum dissection studies on medieval Korean mummies, well preserved internal organs generally were found to have been displaced to the dorsal side of the body cavity. This movement seems to have been caused by the effect of gravitational force exerted over long burial durations. However, when we recently examined a newly discovered medieval Korean mummy (SN1-2) by CT, most of the mummified organs were found to have remained in their natural positions. Our post-factum dissection of SN1-2 showed that the organs might have undergone expansion by posthumous gas formation, after which they hardened into a stone-like state, which mitigated against their displacement. Similar CT findings were made in the case... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4813600 Sat, 26 Mar 2011 00:00:00 +0100 4813600 http://www.medworm.com/index.php?rid=4649536&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21440429%26dopt%3DAbstract Authors: Schneider R, Borges M, Kadyrov M Invasiveness of BeWo cells has been assessed in a variety of assay systems including matrigel and mouse. At the same time BeWo cells are mostly used as model system for trophoblast fusion. Here we aimed to test the properties of BeWo cells in a combined approach. We forced BeWo cells to differentiate by culturing the cells in the presence of forskolin and then used these cells for invasion assays on the chorioallantoic membrane (CAM) of the turkey. The chorioallantoic membranes of turkey eggs were incubated with medium containing forskolin, BeWo cells cultured in medium alone, BeWo cells cultured in forskolin and washed, and BeWo cells cultured in forskolin and used directly for application. Suspensions were applied onto ten CAM per condition. ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4649536 Thu, 24 Mar 2011 00:00:00 +0100 4649536 http://www.medworm.com/index.php?rid=4649535&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21441018%26dopt%3DAbstract Authors: Spindler V, Waschke J Desmosomes are distinct intercellular contacts essential to the integrity of epithelial tissues and the heart muscle. This function is impaired in the disease pemphigus, in which patients develop autoantibodies against the cadherin-type desmosomal core proteins desmogleins. Autoantibody binding induces loss of cell-cell adhesion leading to blisters within the epidermis and mucous membranes. Despite the relevance of desmosomes for integrity of such essential organs as the skin, data on the regulation of desmosome assembly and maintenance and desmosome-mediated adhesion are only slowly emerging. Small guanosine triphosphatases (GTPases) of the Rho family have long been established as regulators of other cell junctions such as adherens junctions, but also ha... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4649535 Sat, 05 Mar 2011 00:00:00 +0100 4649535 http://www.medworm.com/index.php?rid=4530389&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21339059%26dopt%3DAbstract Authors: Hattermann K, Held-Feindt J, Mentlein R Cell migration and tissue invasion is an important issue in tumour and developmental research. Here, we describe the spheroid invasion assay in detail, a method for monitoring migration of different cell types in a three-dimensional model in vitro. Different (or same) cell types are fluorescently labelled with two different dyes, e.g. Vybrant(®) CFDA SE Kit ([5(6)carboxyfluorescein diacetate] succidimidylester, green) or SNARF-1(®) (red), and spheroids of these cells are formed in a medium with 0.24% methylcellulose. After this, spheroids are detached, picked and confronted with each other. After different periods of time, cell invasion can be easily followed microscopically. As an example, the method was applied here to visualize the ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530389 Thu, 03 Feb 2011 00:00:00 +0100 4530389 http://www.medworm.com/index.php?rid=4530398&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21330122%26dopt%3DAbstract CONCLUSION: The different localisation of ADAM12-S and ADAM12-L indicates a possible different role making ADAM12-L a candidate for the fusion event, while the syncytial localisation of the ADAM12-S makes it a candidate for cell-cell and cell-matrix interactions between the placental syncytium and the maternal interface. PMID: 21330122 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530398 Wed, 26 Jan 2011 00:00:00 +0100 4530398 http://www.medworm.com/index.php?rid=4530397&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21330123%26dopt%3DAbstract In conclusion, as demonstrated by the vimentin-positive cells, the injured IVD has endogenous resources that can stem the DDD damage, including substitution of damaged elastic fibers by oxytalan fibers. In addition, induction of apoptosis suggests an increased cell turnover in response to repair needs. PMID: 21330123 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530397 Wed, 26 Jan 2011 00:00:00 +0100 4530397 http://www.medworm.com/index.php?rid=4530395&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21330124%26dopt%3DAbstract CONCLUSIONS: We argue that donor campaigns should not focus solely on altruistic motives, but should include the aspect of possible personal achievement by the donor. This is a fruitful starting point for approaching potential donors and anticipating their needs. PMID: 21330124 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530395 Wed, 26 Jan 2011 00:00:00 +0100 4530395 http://www.medworm.com/index.php?rid=4530394&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21333509%26dopt%3DAbstract Authors: Lazarov NE, Usunoff KG, Schmitt O, Itzev DE, Rolfs A, Wree A Previous neurophysiological studies have demonstrated that the amygdala has a direct influence upon trigeminal motoneuron activity. The existence of a direct amygdalotrigeminal pathway in rats was proved by anterograde tracing with the neuroanatomical tracer, biotinylated dextran amine (BDA). After ipsilateral BDA application to the central nucleus of the amygdala (AmCe), widespread ipsilateral projections emerging from its medial subnucleus were traced to the trigeminal brainstem nuclear complex, including the principal sensory (Pr5) and mesencephalic trigeminal nucleus (Me5), and their premotoneurons and interneurons, located in the supratrigeminal, intertrigeminal and peritrigeminal nuclei. Sparse BDA-labeled axon... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530394 Wed, 26 Jan 2011 00:00:00 +0100 4530394 http://www.medworm.com/index.php?rid=4530393&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21333510%26dopt%3DAbstract Authors: Abdelmalik SW Several studies have presented Garlic (Allium sativum) as a restoring agent for testicular cells after exposure to different types of toxins, however, others have shown that it modified spermatogenesis and might have spermicidal effects. This work has been to assess the positive or negative effect of chronic crude garlic consumption on rat testes using light and transmission electron microscopy with reference to plasma testosterone and LH levels. Forty albino male rats were divided into group A (control) and group B (treated rats). Group B was further subdivided into B1, B2, and B3 subgroups which were administer crude garlic as 20% of their daily food for two, three and four months, respectively. The current study has been the first, to the best of our knowledge... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530393 Wed, 26 Jan 2011 00:00:00 +0100 4530393 http://www.medworm.com/index.php?rid=4530392&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21333511%26dopt%3DAbstract Authors: Bazwinsky-Wutschke I, Paulsen F, Stövesandt D, Holzhausen HJ, Heine HJ, Peschke E Pneumonectomy is associated with many diverse post-operative conditions, e.g. hydropneumothorax, diaphragm elevation, progressive mediastinal displacement, thorax wall deformation, and hydrothorax. By means of imaging procedures, such pneumonectomy-related anatomical changes can easily be determined; here we summarize some of the common diagnostic findings and in addition report the case of a 100-year-old woman, who underwent left pneumonectomy at the age of 47, survived for another 53 years with only one lung and then became body donor to our department. Investigation of the cadaver revealed that, compared to similar-aged individuals still having both lungs, mediastinal structures had been disp... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530392 Wed, 26 Jan 2011 00:00:00 +0100 4530392 http://www.medworm.com/index.php?rid=4530391&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21334866%26dopt%3DAbstract Authors: Katori Y, Rodríguez-Vázquez JF, Kawase T, Murakami G, Cho BH, Abe SI The trochlea for the superior oblique muscle as well as the hamulus for the tensor veli palatini muscle is well known as a fibrocartilage-associated, hard tissue pulley that changes the direction of the tendon. However, details of the fetal development of these structures remain obscure. We carried out a histological study of hematoxylin-eosin-stained preparations from 20 human fetuses (7-15 weeks of gestation) and clarified a common rule for the formation of these pulleys: changing in the location of a structure for the muscle insertion. At the early stage, the muscle and insertion exhibit an almost straight course alongside the primitive pulley, but because the structure for insertion later moves away fro... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530391 Wed, 26 Jan 2011 00:00:00 +0100 4530391 http://www.medworm.com/index.php?rid=4530390&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21334867%26dopt%3DAbstract Authors: Katori Y, Takeuchi H, Rodríguez-Vázquez JF, Kitano H, Murakami G, Kawase T The fetal anatomy of the human epiglottis has not yet been fully described. We investigated the histology (paraffin-embedding) of 18 mid-term fetuses at 7-25 weeks of gestation (three fetuses each at 7, 9, 12, 15, 20 and 25 weeks). A mesenchymal condensation of the epiglottic cartilage appears posterior and somewhat superior to the hyoid body at 9 weeks, but at 12 and 15 weeks, the root or inferior part descends to the level of the thyroid cartilage. The covering epithelium stains much darker with hematoxylin than other pharyngeal epithelia. After 20 weeks, the epiglottis again protrudes superiorly beyond the hyoid body. In contrast to other laryngeal cartilage anlagen, the mesenchymal condensation of... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4530390 Wed, 26 Jan 2011 00:00:00 +0100 4530390 http://www.medworm.com/index.php?rid=4279064&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21167694%26dopt%3DAbstract CONCLUSION: Our precision values compare well with those reported in published studies on landmark location in 3D surface images. PMID: 21167694 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4279064 Tue, 30 Nov 2010 00:00:00 +0100 4279064 http://www.medworm.com/index.php?rid=4279065&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21167693%26dopt%3DAbstract CONCLUSION: Although the sample number is small in this study, it suggests that the human trochlear nucleus can be divided into three parts, and that the overall growth may be accelerated at about 30 weeks of gestation. PMID: 21167693 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4279065 Sat, 27 Nov 2010 00:00:00 +0100 4279065 http://www.medworm.com/index.php?rid=4279063&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21167695%26dopt%3DAbstract Authors: Bekele A, Reissig D, Löffler S, Hinz A Dissection courses in human anatomy are laborious, and new teaching tools have become available. Therefore, some universities intend to reduce the dissection course. Furthermore, little is known about dissection courses in African universities. The aim of this study is to compare the students' experiences with and evaluations of the dissection courses in two universities: Leipzig (Germany) and Gondar (Ethiopia). Since the Gondar Medical College was founded in cooperation with the Leipzig University in 1978, the anatomy courses in both universities follow roughly the same rules. A structured questionnaire was used to assess the dissection courses from the students' point of view. The sample of students consisted of 109 German and 124 Ethi... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4279063 Sat, 27 Nov 2010 00:00:00 +0100 4279063 http://www.medworm.com/index.php?rid=4279062&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21168316%26dopt%3DAbstract Authors: Arciszewski MB, Stefaniak M, Zacharko-Siembida A, Całka J Aquaporins are a large family of small integral membrane proteins that function as molecular water channels. Increasing evidence indicates that an aquaporin 1 (AQP1) water channel is present on the surface of discrete neuronal classes of the central as well peripheral nervous systems. The aim of the present study has been to immunohistochemically localize AQP1 in the enteric nervous system (ENS) of the sheep duodenum. Specific antibodies to vasoactive intestinal polypeptide (VIP) and substance P (SP) were also used to biochemically determine possible function(s) of AQP1-positive enteric neurons. The expression of AQP1 in neuronal cell cultures has been also studied. Under normal conditions, approximately 30% of submuco... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4279062 Sat, 27 Nov 2010 00:00:00 +0100 4279062 http://www.medworm.com/index.php?rid=4279061&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21169000%26dopt%3DAbstract Authors: Panagouli E, Lolis E, Venieratos D An adequate quantity of data on the branching points and important arterial segments of the main arteries in humans is missing. Moreover, a suitable data collection and thereby observed correlations might provide some important clues relating to angiogenesis issues. Thus, we chose to examine in sixty-two embalmed human cadavers of Hellenic origin: The level and angles of the branching points did not differ substantially from similar data, mentioned in the literature. Our results revealed that symmetry exists between the limbs and the aortic length and the branching positions of the abdominal aorta. The aortic length is negatively related to the length of both common iliac arteries. The lengths of the celiac and the brachiocephalic artery (cor... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4279061 Sat, 27 Nov 2010 00:00:00 +0100 4279061 http://www.medworm.com/index.php?rid=4279067&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21145220%26dopt%3DAbstract Authors: Kawashima T, Sasaki H The main aim of this review is to provide macroscopic anatomical information on the human cardiac conduction system (CCS) with comparative morphological and developmental implications for future human application. In the elder human CCS, the sinuatrial node (SAN) is almost consistently positioned on the sulcus terminalis and is variable in size and shape with its extent. However, the atrioventricular CCS that is distal to the atrioventricular node (AVN) varies frequently in shape, size, and position with respect to some conventionally used landmarks. From the comparative anatomical viewpoint, there are marked differences between humans and most mammals and birds not only in the position of atrioventricular CCS in relation to surrounding structures but als... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4279067 Fri, 19 Nov 2010 00:00:00 +0100 4279067 http://www.medworm.com/index.php?rid=4279066&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21145716%26dopt%3DAbstract Authors: Amalinei C, Cianga C, Balan R, Cianga P, Giusca S, Caruntu ID Endometrioid endometrial carcinoma developed from endometrial hyperplasia is associated with anomalies of proliferation, apoptosis, and matrix metalloproteinase (MMP) expression. Our study was designed to investigate steroid receptor (ER, PR) expression and its correlation with proliferative activity (PCNA), apoptosis (Fas, FasL, Bcl-2, Bax, and p53), gelatinases (MMP-2 and MMP-9) and their tissue specific inhibitor (TIMP-1 and TIMP-2) immunoexpression in endometrial carcinogenesis. A total of 38 cases were investigated, 10 non-neoplastic, 11 hyperplastic, and 17 carcinomatous endometria. Immunolabeling showed a higher expression of steroid receptors in hyperplasia and carcinoma than in non-neoplastic endometria and... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4279066 Fri, 19 Nov 2010 00:00:00 +0100 4279066 http://www.medworm.com/index.php?rid=4139957&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21036569%26dopt%3DAbstract CONCLUSION: The specific training curriculum for tutors in the dissection course, focusing on the improvement of content knowledge, technical and didactical competencies, is well accepted by the tutees and tutors. PMID: 21036569 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4139957 Fri, 29 Oct 2010 00:00:00 +0100 4139957 http://www.medworm.com/index.php?rid=4108252&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20971623%26dopt%3DAbstract Authors: Paulsen FP, Eichhorn M, Bräuer L Conventional continuing education in microscopic anatomy, histopathology, hematology and microbiology has hitherto been carried out using numerous sets of sectioned tissue specimens in a microscopy laboratory. In comparison, after digitalization of the sections it would be possible to access teaching specimens via virtual microscopy and the internet at any time and place. This would make it possible to put innumerable new learning scenarios into practice. The present article elucidates the advantages of virtual microscopy in histology instruction and presents a concept of how virtual microscopy could be introduced into the teaching of microscopic anatomy in several steps. Initially, the presently existing microscopic teaching specimens would b... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4108252 Thu, 21 Oct 2010 23:00:00 +0100 4108252 http://www.medworm.com/index.php?rid=4108251&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20971624%26dopt%3DAbstract Authors: Paulsen FP PMID: 20971624 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4108251 Thu, 21 Oct 2010 23:00:00 +0100 4108251 http://www.medworm.com/index.php?rid=4108250&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20971625%26dopt%3DAbstract Authors: Claassen H, Schicht M, Brandt J, Reuse K, Schädlich R, Goldring MB, Guddat SS, Thate A, Paulsen F Sex hormones and insulin have been implicated in articular cartilage metabolism. To supplement previous findings on the regulation of matrix synthesis with 17β-estradiol and insulin and to find a possible model to study cartilage metabolism in vitro, we evaluated the expression of estrogen receptors α and β (ERα, ERβ), androgen receptor (AR) and insulin receptor (IR), in immortalized C-28/I2 and T/C-28a2 chondrocytes and in human primary articular cartilage cells. Chondrocytes were treated with increasing concentrations of 17β-estradiol, dihydrotestosterone or insulin and analyzed by means of RT-PCR and Western blotting. Both cell lines as well as human articular chondrocyt... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4108250 Thu, 21 Oct 2010 23:00:00 +0100 4108250 http://www.medworm.com/index.php?rid=4088895&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20947320%26dopt%3DAbstract Authors: Hirt B, Shiozawa T, Herlan S, Wagner HJ, Küppers E Despite the rapid rise of integrated curricula, the teaching of gross anatomy by traditional dissection remains a central element in most medical programs worldwide. However, modern didactic concepts demand the integration of clinical content in preclinical settings. The implementation of interdisciplinary tools often leads to a reduction in teaching of comprehensive anatomy. 'Tübingen's Sectio chirurgica' (TSC) introduces a concept of a teaching activity in which surgical prosection is performed in addition to the traditional dissection course. TSC is designed to integrate clinical and preclinical content in a traditional medical curriculum without affecting the systematic presentation of anatomical content. In the past 2 y... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4088895 Thu, 16 Sep 2010 23:00:00 +0100 4088895 http://www.medworm.com/index.php?rid=4088894&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20951015%26dopt%3DAbstract Authors: Shin DS, Chung MS, Park JS, Park HS, Lee SB, Lee SH, Choi HN, Riemer M, Handels H, Lee JE, Jung W Unlike volume models, surface models representing hollow, three-dimensional images have a small file size; allowing them to be displayed, rotated, and modified in real time. Therefore, surface models of lumbosacral structures can be effectively used for interactive simulation of, e.g., virtual lumbar puncture, virtual surgery of herniated lumbar discs, and virtual epidural anesthesia. In this paper, we present surface models of extensive lumbosacral structures which can be used in medical simulation systems. One-hundred and thirty-eight chosen structures included the spinal cord, lumbar and sacral nerves, vertebrae, intervertebral discs, ligaments, muscles, arteries, and skin. The... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4088894 Thu, 16 Sep 2010 23:00:00 +0100 4088894 http://www.medworm.com/index.php?rid=4065654&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20932731%26dopt%3DAbstract Authors: Masłoń A, Grzegorzewski A, Lebiedziński R, Topol M Tears of the hip labrum have been recognized as a cause of hip pain and clicking. It has been reported that labrum tears are associated with increased microvessel formation. The purpose of this study was to identify the regional vascularity of the acetabular labrum during late foetal development. The acetabular labrum was examined from 21 formalinized foetuses of the age 5th to 10th months of gestation (mean 6.4±0.99). The acetabulum of each specimen was anatomically prepared and divided into four quadrants. The number of blood vessels in labrum quadrants was counted during microscopic examination. A total of 599 of blood vessels were found in all specimens: 159 in quadrant I, 150 in quadrant II, 127 in quadrant III and 16... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4065654 Thu, 16 Sep 2010 23:00:00 +0100 4065654 http://www.medworm.com/index.php?rid=4010419&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20851584%26dopt%3DAbstract Authors: Schagemann JC, Russlies M, Mittelstädt H Wagner hip arthroplasty has been used as a resurfacing and thereby bone-preserving method for the treatment of disabling osteoarthritis particularly in younger individuals. The underlying rationale was to replace exclusively diseased tissue, to restore anatomy and function and to optimize range of motion and stress transfer to the proximal femur. Wagner's approach was designed to reduce the risk of infection and to make later revisions easier. The technique was however associated with a high revision rate due to early aseptic wear induced component loosening and neck fractures. Nevertheless, we report a case of a 30 years follow-up of a Wagner resurfacing hip arthroplasty. PMID: 20851584 [PubMed - as supplied by publisher] (Sourc... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4010419 Wed, 25 Aug 2010 23:00:00 +0100 4010419 http://www.medworm.com/index.php?rid=4010420&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20846838%26dopt%3DAbstract Authors: Boeckers A, Brinkmann A, Jerg-Bretzke L, Lamp C, Traue HC, Boeckers TM The dissection course (DC) is an essential part of the preclinical medical curriculum that mediates professionalism. The process of dissecting, however, has an inherent additional stress potential. Our study determined student mental stress, their need of psychological support and factors influencing this need. A quantitative longitudinal query before, during and after the DC was performed including the Brief Symptom Inventory (BSI) as well as self-formulated questions used a 5-point Likert scale. Half of the students who anticipated dissection to be a stress factor reported that this declined significantly over time. Instead, student fear of not being able to cope with the work load increased significantly... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4010420 Wed, 18 Aug 2010 23:00:00 +0100 4010420 http://www.medworm.com/index.php?rid=4010421&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20833519%26dopt%3DAbstract In conclusion, our data indicate that muscle fibre hypertrophy precedes the acquisition of new myonuclei and that the ability to develop hypertrophy is not attenuated or delayed in 25-month-old rat muscle. PMID: 20833519 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=4010421 Mon, 16 Aug 2010 23:00:00 +0100 4010421 http://www.medworm.com/index.php?rid=3962551&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20829010%26dopt%3DAbstract Authors: Janczyk P, Weigner J, Luebke-Becker A, Kaessmeyer S, Plendl J Formaldehyde, the traditional embalming agent has negative health effects. Nitrite pickling salt has been reported to be a good and inexpensive alternative when supplemented with antioxidants, but the antioxidants caused yellowish colouration of cadavers, and damaged corrosion-resistant steel tables and stone floors. Here, nitrite pickling salt was supplemented with ethanol and Pluriol(®) and tested for effectiveness as an embalming agent of twenty dog cadavers: 10 with open, and 10 with closed abdominal cavity. The texture of the tissue was monitored intermittently for 12 months throughout the course of an anatomical dissection class. Histological and microbiological analysis of samples from muscles, lungs, duod... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3962551 Mon, 16 Aug 2010 23:00:00 +0100 3962551 http://www.medworm.com/index.php?rid=3934842&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20807677%26dopt%3DAbstract Authors: Rusu MC, Pop F, Boşcu AL, Jianu AM, Dermengiu D, Curcă GC, Hostiuc S The anatomy of the tracheal microinnervation is understudied in humans; the purpose of our study was to fill this gap by working on human adult tracheas, to compare the results with those obtained from animal studies, and to checking whether or not these studies are suitable to be translated from comparative to the human anatomy. The study was designed as a qualitative one. The present work was performed on human adult tracheas dissected out in 15 human adult cadavers. Microdissections were performed in eight tracheas and revealed the outer peritracheal plexus, segmentally supplied and distributed to trachea and esophagus, with longitudinal intersegmentary anastomoses but also with bilateral interrecurr... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3934842 Thu, 12 Aug 2010 23:00:00 +0100 3934842 http://www.medworm.com/index.php?rid=3934845&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20739154%26dopt%3DAbstract Authors: Klonisch T PMID: 20739154 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3934845 Thu, 05 Aug 2010 23:00:00 +0100 3934845 http://www.medworm.com/index.php?rid=3934844&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20739155%26dopt%3DAbstract Authors: Barber BA, Rastegar M The process of mammalian development is established through multiple complex molecular pathways acting in harmony at the genomic, proteomic, and epigenomic levels. The outcome is profoundly influenced by the role of epigenetics through transcriptional regulation of key developmental genes. Epigenetics refer to changes in gene expression that are inherited through mechanisms other than the underlying DNA sequence, which control cellular morphology and identity. It is currently well accepted that epigenetics play central roles in regulating mammalian development and cellular differentiation by dictating cell fate decisions via regulation of specific genes. Among these genes are the Hox family members, which are master regulators of embryonic development and... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3934844 Thu, 05 Aug 2010 23:00:00 +0100 3934844 http://www.medworm.com/index.php?rid=3934843&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20800459%26dopt%3DAbstract Authors: Klonisch T, Wark L, Hombach-Klonisch S, Mai S Tumorigenesis includes alterations in the three-dimensional (3D) nuclear organization of the genome. The combination of sensitive quantitative fluorescent in situ hybridization (Q-FISH) and three-dimensional (3D) microscopy have evolved as powerful tools in studying the dynamic 3D organization of telomeres and chromosomes in the interphase nucleus of individual normal and tumor cells. Tumor-specific alterations in 3D telomere architecture, particularly the appearance of telomeric aggregates, are early events in tumorigenesis and have diagnostic and prognostic value. Novel tools in the 3D nuclear imaging arsenal now include high-throughput scanning capabilities and new 3D nano-resolution microscopy of tissues and cells. In this revi... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3934843 Thu, 05 Aug 2010 23:00:00 +0100 3934843 http://www.medworm.com/index.php?rid=3934841&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20810259%26dopt%3DAbstract Authors: Knecht H, Brüderlein S, Mai S, Möller P, Sawan B Recent research using an innovative 3D quantitative FISH approach of nuclear remodelling associated with the transition from mononuclear Hodgkin to diagnostic multinuclear Reed-Sternberg cells revealed profound changes in the 3D nuclear organization of telomeres. Analogous 3D telomere dynamics were identified in Hodgkin's lymphoma derived cell-lines and diagnostic patient biopsies. These changes were observed in both, EBV positive and EBV-negative Hodgkin's lymphoma and independent of the age of the patients at presentation. Compared to mononuclear Hodgkin cells, multinuclear Reed-Sternberg cells are characterized by a highly significant increase of telomere aggregates, often composed of very short telomeres, telomere shor... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3934841 Thu, 05 Aug 2010 23:00:00 +0100 3934841 http://www.medworm.com/index.php?rid=3934840&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20810260%26dopt%3DAbstract Authors: Li L, Davie JR Sp1 and Sp3 are transcription factors expressed in all mammalian cells. These factors are involved in regulating the transcriptional activity of genes implicated in most cellular processes. Dysregulation of Sp1 and Sp3 is observed in many cancers and diseases. Due to the amino acid sequence similarity of the DNA binding domains, Sp1 and Sp3 recognize and associate with the same DNA element with similar affinity. However, others and our laboratory demonstrated that these two factors possess different properties and exert different functional roles. Both Sp1 and Sp3 can interact with and recruit a large number of proteins including the transcription initiation complex, histone modifying enzymes and chromatin remodeling complexes, which strongly suggest that Sp1 an... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3934840 Thu, 05 Aug 2010 23:00:00 +0100 3934840 http://www.medworm.com/index.php?rid=3900906&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20732797%26dopt%3DAbstract Authors: Samassekou O, Gadji M, Drouin R, Yan J The ends of human chromosomes are constituted of telomeres, a nucleoprotein complex. They are mainly formed by the entanglement of repeat DNA and telomeric and non-telomeric proteins. Telomeric sequences are lost in each cell division and this loss happens in vitro as well as in vivo. The diminution of telomere length over the cell cycle has led to the consideration of telomeres as a 'mitotic clock'. Telomere lengths are heterogeneous because they differ among tissues, cells, and chromosome arms. Cell proliferation capacity, cellular environment, and epigenetic factors are some elements that affect this telomere heterogeneity. Also, genetic and environmental factors modulate the difference in telomere lengths between individuals. Telomere... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3900906 Thu, 05 Aug 2010 23:00:00 +0100 3900906 http://www.medworm.com/index.php?rid=3900905&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20732798%26dopt%3DAbstract Authors: Cho KH, Rodríguez-Vázquez JF, Han EH, Verdugo-López S, Murakami G, Cho BH Development of the meninges in and around the plica ventralis encephali has not been well documented. A distinct mesenchymal structure, the so-called plica ventralis encephali, is sandwiched by the fetal mesencephalic flexure. We histologically examined paraffin-embedded sections from 18 human embryos and fetuses at 6-12 weeks of gestation. In the loose tissues of the plica, the first meninx appeared as a narrow membrane along the oculomotor nerve at 7-8 weeks. Subsequently, the plica ventralis evolved into 3 parts: bilateral lateral mesenchymal condensations and a primitive membranous meninx extending between. Notably, the topographical anatomy of the oculomotor, trochlear and trigeminal nerves... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3900905 Thu, 05 Aug 2010 23:00:00 +0100 3900905 http://www.medworm.com/index.php?rid=3873193&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20692821%26dopt%3DAbstract Authors: Batoulis H, Addicks K, Kuerten S Multiple sclerosis (MS) and its animal model experimental autoimmune encephalomyelitis (EAE) have long been regarded as primarily T helper cell type 1-mediated diseases. However, recent evidence suggests that T(H)17 cells, a mostly unexplored subset of T helper cells, may be even more pathogenic than T(H)1 cells. In the EAE model, this cell type is crucial for the recruitment of leukocytes into the CNS and for triggering parenchymal inflammation. In humans, T(H)17 cells are found in acutely active and on the borders of chronically active lesions. Overall, CD4(+) T cells only recognize antigens presented on MHC class II complexes, and these are seldom found in the CNS. MHC class I, in contrast, can be induced on neurons and myelin. This also mak... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3873193 Wed, 14 Jul 2010 23:00:00 +0100 3873193 http://www.medworm.com/index.php?rid=3873192&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20696558%26dopt%3DAbstract The objectives of this work were to make medical students, at the pre-clinical stage of their medical carrier, alert to diagnosis and handling of clinical problems and to develop their ability to integrate pre-clinical and clinical subjects. Fifty human cadaveric hearts were anatomically and histopathologically examined. This examination revealed six different clinical problems such as pericarditis, myocarditis, cardiac hypertrophy, parasitic infestation, rheumatic heart disease and fatty infiltration. The medical students of the second year will be first introduced to the normal anatomical and histological structure of the heart, then allowed to visualize and examine the specimens of the cadaveric heart both macroscopically and microscopically. They will be introduced to a set of clinical... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3873192 Wed, 14 Jul 2010 23:00:00 +0100 3873192 http://www.medworm.com/index.php?rid=3833815&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20685095%26dopt%3DAbstract Authors: Saino-Saito S, Suzuki R, Tokuda N, Abe H, Kondo H, Owada Y Various fatty acids (FAs) are involved in many different functions in the organism as a source of energy, as essential ingredients of membranous lipids as well as intracellular signaling molecules. Intracellular fatty acid binding proteins (FABPs) comprise a family of soluble lipid binding proteins with low molecular masses and which can make long chain FAs soluble to allow intracellular translocation in the aqueous cytosol. To clarify the possible involvement of FAs and FABPs in hearing function, the present study investigated the localization of FABPs in the cochlea of adult mice using immunohistochemical procedures. Among various FABP species, H (heart-type)-FABP was localized in inner and outer pillar cells and out... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3833815 Wed, 14 Jul 2010 23:00:00 +0100 3833815 http://www.medworm.com/index.php?rid=3833814&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20685096%26dopt%3DAbstract Authors: Miething A Mammalian male germ cells go through the process of spermatogenesis as cell clones. The members of a clone are joined by intercellular bridges which are responsible for synchronizing the spermatogenetic process. The present ultrastructural study on pubertal and adult golden hamster and mouse testes, however, demonstrates that a strict synchronization of germ cell development is not attained by this clonal association in any single instance. Local desynchronization is either indicated by intraclonal divergence at the stage of the cell cycle of the respective germ cells or it is manifested in clones in which single cells are affected by degeneration while other members of the clone are not. The results are discussed with a view to a possible significance of intraclona... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3833814 Wed, 14 Jul 2010 23:00:00 +0100 3833814 http://www.medworm.com/index.php?rid=3777637&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20643535%26dopt%3DAbstract Authors: Ebrahimi F, Hezel M, Koch M, Ghadban C, Korf HW, Dehghani F Organotypic hippocampal slice cultures (OHSCs) are widely used to study the mechanisms of neurodegeneration and neuroprotection. However, there are still controversies about the most appropriate method for quantification of neuronal damage. The response to excitotoxic lesions can be determined by propidium iodide (PI) staining, which labels nuclei of degenerating cells. Semiquantitative measurements of PI staining are based on (1) recording of the propidium iodide (PI) fluorescence intensity or (2) counting of PI positive neuronal nuclei. Here, we investigated OHSCs lesioned by the application of increasing NMDA concentrations (10muM, 50muM and 500muM) at 6 days in vitro (div) for 4h or left untreated, respectively. A... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3777637 Thu, 24 Jun 2010 23:00:00 +0100 3777637 http://www.medworm.com/index.php?rid=3722213&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20594814%26dopt%3DAbstract CONCLUSION: Our findings suggest the applicability of SEM for bone surface morphology and demineralized paraffin sections (HE staining) for frontal plane evaluation. Fixed and non-fixed bone specimens seem to be equal in their morphology and can both be used in these kinds of studies. PMID: 20594814 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3722213 Fri, 11 Jun 2010 23:00:00 +0100 3722213 http://www.medworm.com/index.php?rid=3722217&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20591638%26dopt%3DAbstract Authors: Römer P, Weingärtner J, Roldán JC, Proff P, Reicheneder C The spheno-occipital synchondrosis is part of the cranial base growth plate and is of crucial importance in craniofacial development. In this investigation, we studied changes in collagen gene expression in the spheno-occipital synchondrosis in order to identify the developmental stages most important for extracellular matrix production and ossification of the rat cranial base growth plate. Gene transcripts of type II and X collagen were most abundant at day 10 postnatally in the spheno-occipital synchondrosis. This observation is assumed to be due to intrinsic genetic factors and local environmental factors. PMID: 20591638 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3722217 Thu, 10 Jun 2010 23:00:00 +0100 3722217 http://www.medworm.com/index.php?rid=3722216&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20591639%26dopt%3DAbstract CONCLUSIONS: The results indicate that the natal teeth were prematurely erupted regular primary mandibular central incisors. In our case, the occurrence of natal teeth associated with agenesis of their primary successors appears to be related to an accelerated or premature pattern of dental development, rather than to superficial positioning of the tooth germs. PMID: 20591639 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3722216 Thu, 10 Jun 2010 23:00:00 +0100 3722216 http://www.medworm.com/index.php?rid=3722215&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20591640%26dopt%3DAbstract Authors: Arnold WH, Becher S, Widera D, Jacob M, Mannherz HG, Dittmar T, Grimm WD The aim of this study has been to characterize adult human somatic periodontium-derived stem cells (PDSCS) isolated from human periodontium and to follow their differentiation after cell culture. PDSCS were isolated from human periodontal tissue and cultured as spheres in serum-free medium. After 10 days the primary spheres were dissociated and the secondary spheres sub-cultured for another 1-2 weeks. Cells from different time points were analyzed, and immunohistochemical and electron microscopic investigations carried out. Histological analysis showed differentiation of spheres deriving from the PDSCS with central production of extracellular matrix beginning 3 days after sub-culturing. Isolated PDSCS dev... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3722215 Thu, 10 Jun 2010 23:00:00 +0100 3722215 http://www.medworm.com/index.php?rid=3722214&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20591641%26dopt%3DAbstract CONCLUSION: Our results underline the relevance of basic sciences (gross anatomy, physiology, and pharmacology) in daily professional activity. Evidence-based studies such as ours, lend greater credibility and objectivity to the role of gross anatomy in the undergraduate training of health professionals and should help to establish a more appropriate curriculum for future professionals. PMID: 20591641 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3722214 Thu, 10 Jun 2010 23:00:00 +0100 3722214 http://www.medworm.com/index.php?rid=3522923&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20427168%26dopt%3DAbstract Authors: Mohamed SA, Misfeld M, Hanke T, Charitos EI, Bullerdiek J, Belge G, Kuehnel W, Sievers HH Apoptosis of vascular smooth muscle cells (VSMCs) is involved in bicuspid aortic valve (BAV) ascending aorta aneurysms characteristically affecting the convex site. Caspase-3 is a pivotal effector of the apoptosis machinery. The aim of this study was to investigate the impact of an inhibited caspase-3 pathway on apoptosis in convex and concave sites VSMCs of ascending aortic tissue in vitro. Specimens from the convex and concave sites of ascending aortic aneurysm were collected from nine patients with BAV (mean age 58.7+/-14.8). Cultured VSMCs were characterized morphologically and immunohistochemically. Apoptosis activity was measured in VSMCs using Annexin V-APC with propidium iodide nu... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3522923 Sat, 10 Apr 2010 23:00:00 +0100 3522923 http://www.medworm.com/index.php?rid=3483643&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20399088%26dopt%3DAbstract Authors: Hohendorff B, Weidermann C, Burkhart KJ, Rommens PM, Prommersberger KJ, Konerding MA We obtained data on the lengths, girths, and diameters of the fingers of children from 3 to 10 years of age. A total of 160 children (78 girls, 82 boys) were examined in a cross-sectional investigation. The length of each finger of the right hand of every child was measured, as were the girths of the proximal, middle, and distal phalanges, and of the proximal and distal interphalangeal joint. The average length of the thumb was 49 (35-65)mm. The index and ring fingers both averaged 69 (index, 50-88; ring, 42-96)mm in length, while the middle and little fingers averaged 72 (57-100) and 56 (40-74)mm, respectively. Average diameter, calculated from the girth measurement, was 16 (11-22)mm for the ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3483643 Fri, 02 Apr 2010 23:00:00 +0100 3483643 http://www.medworm.com/index.php?rid=3483642&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20400279%26dopt%3DAbstract Authors: Theilig F Chronic kidney disease is characterized by the decline in renal excretory, homeostatic and endocrine functions. In most instances, the primary event is glomerular injury. With ongoing progression and glomerular extracapillary proliferation, tubulointerstitial damage occurs with consequent nephron loss and development of fibrotic lesions, finally resulting in terminal renal failure. Renal tubulointerstitial damage is the final common pathway in all forms of renal disease leading to CKD. Recent research has focused on how glomerular injury spreads to the tubulointerstitium. Presently, four possible mechanisms are being discussed: (1) obstruction of the urinary pole; (2) proteinuria-induced overload of the proximal tubule; (3) chronic hypoxia and (4) inflammation induce... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3483642 Fri, 02 Apr 2010 23:00:00 +0100 3483642 http://www.medworm.com/index.php?rid=3480786&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20395119%26dopt%3DAbstract Authors: Hammer A In an attempt to determine the position and course of the horizontal trabecular column within the femoral neck a series of femoral necks were dissected using a physical method. Unexpectedly, the findings of the study show that the internal structure of the femoral neck, overall, is more complex than has been previously described. Both trabecular columns blend intimately with the overlying cortex in the manner of a composite structure, which may have implications as to their strength. It was noted, as previously described in the literature, that the horizontal column has a spiral configuration. In addition it was found, in this study, that this column shows wide variation in its inclination between different specimens. With increasing osteoporosis, the remnant of the h... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3480786 Mon, 29 Mar 2010 23:00:00 +0100 3480786 http://www.medworm.com/index.php?rid=3480785&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20395120%26dopt%3DAbstract In conclusion, tissue microarrays enable the observation of Glut-1 expression in peri-necrotic regions, which may be linked to hypoxia, and reflect previous studies showing differential Glut-1 expression across tumor types and non-malignant tissue. PMID: 20395120 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3480785 Wed, 24 Mar 2010 00:00:00 +0100 3480785 http://www.medworm.com/index.php?rid=3468381&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20382512%26dopt%3DAbstract CONCLUSIONS: Correlations between the side-dependent parameters and the AIL and the PIL of the same side indicate close functional relationships. Additional dependencies suggest that the IL is capable of compensating age-related as well as bone-attributed alterations in lumbosacral morphology. The IL data and the visualised ligament structures contribute to determination of the influence of the IL in spinal and sacroiliac stability by means of computer-assisted biomechanics. PMID: 20382512 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3468381 Wed, 24 Mar 2010 00:00:00 +0100 3468381 http://www.medworm.com/index.php?rid=3468380&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20385476%26dopt%3DAbstract CONCLUSIONS: This study shows that a three-day anatomy revision course is effective and highly appreciated by medical students in their preparation for the national exam. Moreover, peer-teaching is reliable at this stage of the medical curriculum. PMID: 20385476 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3468380 Wed, 24 Mar 2010 00:00:00 +0100 3468380 http://www.medworm.com/index.php?rid=3441348&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20363112%26dopt%3DAbstract In this report we discuss the technical requirements, system efficiency, optical resolution and didactic concept. Furthermore, we present a review of the experience gained in the course of one year based on an analysis of student acceptance. Three groups with a total of 192 students between the 3rd and 5th year of medical studies attending the practical courses of general and advanced histopathology had access to both glass-mounted and digitalized slides. Prior to exams, students were asked to answer an anonymous questionnaire. The results of the study reflect the high acceptance and intensive use of the web-based digital histology by students, thus encouraging the development of further Web-based learning strategies for the teaching of histology and pathology. PMID: 20363112 [PubMed -... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3441348 Mon, 15 Mar 2010 00:00:00 +0100 3441348 http://www.medworm.com/index.php?rid=3400040&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20307963%26dopt%3DAbstract Authors: Jäger K, Garreis F, Posa A, Dunse M, Paulsen FP The ocular surface, constantly exposed to environmental pathogens, is particularly vulnerable to infection. Hence an advanced immune defence system is essential to protect the eye from microbial attack. Antimicrobial peptides, such as beta-defensins, are essential components of the innate immune system and are the first line of defence against invaders of the eye. High concentrations of l-arginine and l-lysine are necessary for the expression of beta-defensins. These are supplied by epithelial cells in inflammatory processes. The limiting factor for initiation of beta-defensin production is the transport of l-arginine and l-lysine into the cell. This transport is performed to 80% by only one transporter system in the human, ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3400040 Sat, 20 Feb 2010 00:00:00 +0100 3400040 http://www.medworm.com/index.php?rid=3322772&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20189785%26dopt%3DAbstract Authors: Ay H, Ulupınar E, Unal N Viscerocranial anomalies are induced in the presence of various teratogens. Vitamin A-induced cleft palate formation is one of the most frequently used experimental models in these studies. However, the underlying mechanisms are not yet fully understood. Several studies have shown that exogenous vitamin A disrupts the fusion of the palatal shelves by increasing the expression of epidermal growth factor receptor (EGFR). More recently, pyridoxine (vitamin B6) has been reported to have a potentially protective effect in regard to viscerocranial malformations. Therefore, in this study, we aimed to investigate whether pyridoxine has a preventive effect on retinyl palmitate-induced viscerocranial anomalies. The frequency of gross malformations induced ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3322772 Sat, 20 Feb 2010 00:00:00 +0100 3322772 http://www.medworm.com/index.php?rid=3322773&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20188530%26dopt%3DAbstract CONCLUSIONS: The majority of motives for body donation stem from the wish to be useful after death. However, the present survey suggests that body donation is more than an altruistic act; people are also motivated by personal benefit. Results of our survey contradict the notion that body donation stems from loneliness. Many donors have a supportive social network and meaningful social relationships. People moreover propagate body donation within their social networks. PMID: 20188530 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3322773 Wed, 17 Feb 2010 00:00:00 +0100 3322773 http://www.medworm.com/index.php?rid=3270047&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20149607%26dopt%3DAbstract This study indicates prominent type I collagen expression at day 10 postpartum in the mandibular ramus and at day 21 in the alveolar process. These findings correspond well with previously obtained data from proliferation studies in facial bone suggesting that craniofacial growth in the rat occurs mainly between days 10 and 21. PMID: 20149607 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3270047 Mon, 01 Feb 2010 00:00:00 +0100 3270047 http://www.medworm.com/index.php?rid=3270046&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20149608%26dopt%3DAbstract Authors: Kubíček L, Kopáčik R, Klusáková I, Dubový P An alteration in the structural arrangement of blood vessels identified by RECA immunohistochemistry was studied in a rat L4 dorsal root ganglia (L4-DRG) neuropathic pain model. We compared a three-dimensional (3-D) reconstruction of the vascular architecture surrounding bodies of the primary sensory neurons in the L4-DRG of naïve rats with that of rats that had surgically undergone unilateral sciatic nerve ligature. Rhodamine-conjugated dextran (Fluoro-Ruby) was used for retrograde labelling of neurons, the axons of which had been injured by nerve ligature. In contrast to DRG from naïve rats and contralateral DRG from operated rats, an increased proportion of RECA+ vascular area and the... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3270046 Mon, 01 Feb 2010 00:00:00 +0100 3270046 http://www.medworm.com/index.php?rid=3270048&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20149606%26dopt%3DAbstract Authors: Mobasheri A, Moskaluk CA, Marples D, Shakibaei M Rheumatoid arthritis (RA) is an autoimmune disorder characterized by synovial proliferation (synovitis), articular cartilage and subchondral bone degradation as well as joint swelling. Joint swelling and edema often accompany pannus formation and chronic joint inflammation in RA. We have recently shown that human chondrocytes and synoviocytes express aquaporin 1 (AQP1) water channels and that AQP1 is upregulated in RA cartilage. Clinical evidence suggests that joint swelling and edema accompany the chronic inflammation observed in synovial joints of RA patients. Therefore we hypothesized that AQP1 water channels may be involved in joint swelling and synovial edema formation. To test this hypothesis, we performed immunostaining o... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3270048 Mon, 25 Jan 2010 00:00:00 +0100 3270048 http://www.medworm.com/index.php?rid=3270045&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20149609%26dopt%3DAbstract Authors: Steding G, Jian Y Based on scanning electron microscopic dissections of human embryos and fetuses of the sixth to the twelfth week (Carnegie stages 16-23 and early fetus), the origin of the nasal septum was studied. The findings show that the nasal septum does not grow downwards. It is derived from the tissue between the primary choanae: as such, its anlage is present from the very beginning. Its contact and fusion with the palatal shelves is made possible by the elevation of the palatal shelves from the vertical into the horizontal position, as the tongue descends. PMID: 20149609 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3270045 Mon, 25 Jan 2010 00:00:00 +0100 3270045 http://www.medworm.com/index.php?rid=3255427&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20138488%26dopt%3DAbstract CONCLUSIONS: The amount of adipose tissue in LACN non-fascicular area was found to be high at all ages. The presence of less adipose tissue and collagen fibers in the non-fascicular area of the AMACN (below 60 years) could be used for successful nerve grafting when compared to LACN. PMID: 20138488 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3255427 Mon, 25 Jan 2010 00:00:00 +0100 3255427 http://www.medworm.com/index.php?rid=3255426&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20138489%26dopt%3DAbstract This study analyses the severity and distribution of mineralization defects in the dentin of red and roe deer teeth (mandibular fourth premolars, first and third molars) obtained from individuals that had lived in a fluoride-polluted area along the Czech-German border. Mineralization defects presented as hypomineralized or interglobular dentin. In the P(4)s and M(3)s the entire dentin exhibited areas of defective mineralization, whereas in the M(1)s only the central and inner dentin portions were affected. This suggests that the early periods of dentin formation in the first molar, occurring during the late fetal and early postnatal (milk-feeding) periods of life, are protected against exposure to excess fluoride levels. Our findings are consistent with the hypothesis that certain protecti... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3255426 Mon, 25 Jan 2010 00:00:00 +0100 3255426 http://www.medworm.com/index.php?rid=3037149&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19942420%26dopt%3DAbstract Authors: Meyer W, Kacza J, Schnapper A, Verspohl J, Hornickel I, Seeger J Based on cryo-SEM, standard and high resolution TEM, glycoconjugate histochemistry, and microbiological differentiation, the present study demonstrates the colonisation of the epithelium of the equine oesophagus with microorganisms. As particularly apparent using cryo-SEM to illustrate natural conditions, the present microbiota were clearly dominated by bacteria, forming a one-layer system, as attached to and embedded in concentrated mannose/mannan substances covering the outer stratum corneal cells. Bacterial numbers ranged from 5600 to 7200permm(2) in the central part of the oesophagus, the number of fungi was less than 1% of the amount of bacteria. The compact stratum corneal cells showed numerous short protru... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3037149 Fri, 06 Nov 2009 00:00:00 +0100 3037149 http://www.medworm.com/index.php?rid=3034157&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19939656%26dopt%3DAbstract Authors: Rusu MC, Pop F Generally, sympathetic distribution in the pterygopalatine fossa (PPF) is considered to be via the pterygopalatine ganglion (PPG) sympathetic root and branches. We hypothesized that there may be a dual sympathetic path within the PPF, through the vidian nerve and the PPG and through the periarterial plexuses. We dissected 10 human adult cadavers, fixed and unfixed; we applied antibodies for tyrosine hydroxylase (TH) to 5 human adult samples of PPF contents dissected from cadavers at autopsy. We identified TH(+) nerves and fibers distributed through the neuronal clusters of the PPG and also bundles extrinsic to these clusters, distributed along the maxillary artery. Also, TH(+) reactions were identified at the level of the neuronal capsules of the PPG. All the ar... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3034157 Thu, 05 Nov 2009 00:00:00 +0100 3034157 http://www.medworm.com/index.php?rid=3003862&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19914813%26dopt%3DAbstract Authors: Castelo PM, Pereira LJ, Bonjardim LR, Gavião MB The study of stomatognathic system development can provide useful data for recognition of deviations from normality. Thus, a longitudinal examination of 14 children with normal occlusion from primary (stage I, mean age 59.21+/-8.40 months) to early mixed dentition (stage II, 77.57+/-5.92) was performed. Bite force was measured with a pressurized tube and correlated with ultrasonographic masseter and anterior portion of temporalis muscle thicknesses (at rest and maximal intercuspation), facial dimensions, age, and body mass index (BMI). Facial dimensions were assessed by standardized frontal photographs as follows: anterior facial height (AFH), lower face height (LFH), and bizygomatic width (BFW). Children with malocclusion, ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=3003862 Wed, 04 Nov 2009 00:00:00 +0100 3003862 http://www.medworm.com/index.php?rid=2963436&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19883997%26dopt%3DAbstract Authors: Rea PM, McGarry G, Shaw-Dunn J In addition to using intra-operative facial nerve monitoring in helping to locate the position of the facial nerve in anterograde parotidectomy, numerous soft tissue and bony landmarks have been proposed to assist the surgeon in the early identification of this nerve. There is still dispute within the literature as to the most effective method, if any, of locating the nerve. The purpose of this study was to measure the distance (in twenty-six embalmed cadavers) from four of the most commonly used surgical landmarks to the main trunk of the facial nerve-the posterior belly of digastric muscle (PBDM), the tragal pointer (TP), the junction between the bony and cartilaginous ear canal (EAM) and the tympanomastoid suture (TMS). The main trunk of the f... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2963436 Sat, 31 Oct 2009 00:00:00 +0100 2963436 http://www.medworm.com/index.php?rid=2955139&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19880298%26dopt%3DAbstract This study showed that vasoconstriction of the femoral artery in WKY rats was stronger than that of SHR rats. This may be a pathomechanical factor in femoral head necrosis of WKY rats. PMID: 19880298 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2955139 Fri, 30 Oct 2009 00:00:00 +0100 2955139 http://www.medworm.com/index.php?rid=2955140&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19879113%26dopt%3DAbstract This study reveals, in human tissues, the specific expression of FXYD proteins, which may associate with Na, K-ATPase in selected cell types and modulate its catalytic properties. PMID: 19879113 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2955140 Wed, 07 Oct 2009 00:00:00 +0100 2955140 http://www.medworm.com/index.php?rid=2955138&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19880299%26dopt%3DAbstract CONCLUSIONS: The present study provides the first method to reliably model the number of incoming deceased donors of a body donation program for 5 years based on actuarial predictions, and to orchestrate these numbers by partial donor registration stops. PMID: 19880299 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2955138 Wed, 07 Oct 2009 00:00:00 +0100 2955138 http://www.medworm.com/index.php?rid=2866162&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19800774%26dopt%3DAbstract Authors: Topol M, Masłoń A Interest in the role of the pulmonary lymphatic system in the pathophysiology of pulmonary and systemic diseases induced us to carry out anatomical research on the lung lymphatic system in the Polish population. The aim of the study was to evaluate whether lymphatic vessels respect bronchopulmonary segment borders and to determine how often lymphatic vessels run to nodes of another lymphatic region. A block of organs comprising the lungs with the trachea, larynx and tongue, the heart and esophagus was removed from the cadavers at autopsy. The research involved 96 lungs (48 left and 48 right), which were taken from 31 male and 17 female cadavers. The lymphatic vessels were visualized at the mediastinal and interlobar surface of the lung by visual i... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2866162 Thu, 10 Sep 2009 23:00:00 +0100 2866162 http://www.medworm.com/index.php?rid=2839665&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783417%26dopt%3DAbstract Authors: von Bohlen Und Halbach O Most excitatory input in the hippocampus impinges on dendritic spines. Therefore, the dendritic spines are likely to be of major importance for neural processing. The morphology of dendritic spines is very diverse and changes in spine size as well as in their density are thought to reflect changes in the strength of synaptic transmission. Thus, alterations in dendritic spine densities or shape are suspected to be morphological manifestations of psychopathological, pathophysiological, physiological and/or behavioural changes. However, in spite of a long history of research, the specific function of dendritic spines within the hippocampal formation is still not well understood. This review will shed light on the hippocampal dendritic spines, their ultras... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2839665 Sat, 05 Sep 2009 23:00:00 +0100 2839665 http://www.medworm.com/index.php?rid=2832567&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19773150%26dopt%3DAbstract CONCLUSIONS: Due to the small number of cases, the mechanisms and preconditions of osseous metaplasia of the lens are not understood in detail, but injury to the lens capsule and availability of blood supply are being discussed. Both were present in this case, in which the luxated lens ended up in the ciliary body region. The mechanism resembled enchondral ossification rather than intramembranous ossification, which is seen in osseous metaplasia of other intraocular structures. PMID: 19773150 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2832567 Thu, 03 Sep 2009 23:00:00 +0100 2832567 http://www.medworm.com/index.php?rid=2824922&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19766471%26dopt%3DAbstract Authors: Nag TC, Wadhwa S Retinal photoreceptor and bipolar cell axon terminals possess synaptic ribbons (SR) that aid in the trafficking of synaptic vesicles at active zones. In rodents, besides SR, a number of other synaptic elements [e.g., synaptic spheres (SS)] are known to appear when exposed to altered ambient illumination. Here, we report changes of ribbon shape in photoreceptor and bipolar cell axon terminals in retinas of two persons at autopsy who suffered from brain hemorrhage. In both subjects, retinal hemorrhage was present in the outer and inner nuclear layers. SR were bent or swollen and transformed into SS. A count revealed that about 54-60% of the photoreceptor axon terminals over the nasal to temporal retina possessed SS. They were associated with synaptic triads or r... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2824922 Thu, 03 Sep 2009 23:00:00 +0100 2824922 http://www.medworm.com/index.php?rid=2824923&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19765961%26dopt%3DAbstract Authors: Albrecht M Human testicular peritubular cells are myofibroblast-like cells that surround the seminiferous tubules and are responsible for tubular contractility and sperm transport. In the last few years, several reports have augmented this simplified view, showing that peritubular cells are not only structural cells but also actively secrete paracrine mediators, thereby influencing the homeostasis of the testicular environment. This review is focussed on general aspects and functions of testicular peritubular cells, their potential role in male infertility and also on the recently described in vitro culture systems of human testicular peritubular cells, which will enable us to gain deeper insight into the regulation and functions of this peculiar cell type in health and diseas... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2824923 Thu, 27 Aug 2009 23:00:00 +0100 2824923 http://www.medworm.com/index.php?rid=2775430&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19734029%26dopt%3DAbstract Authors: Szaro P, Witkowski G, Smigielski R, Krajewski P, Ciszek B The Achilles or calcaneal tendon is the structural base for the biomechanical work of the ankle joint. The purpose of this study is to describe the internal structure of the human Achilles tendon. The anatomy of the Achilles tendon has been described in lower mammals in which it has three parts which can be dissected from its beginning to the insertion onto the calcaneus. The partial ruptures of each part suggest that the human Achilles tendon may also be composed of parts. The Achilles tendon is one of the most commonly torn tendons in the human body. Each segment of the Achilles tendon described by us can be ruptured separately, which can cause a partial dysfunction in flexion of the ankle joint as observed in clinica... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2775430 Wed, 19 Aug 2009 23:00:00 +0100 2775430 http://www.medworm.com/index.php?rid=2752695&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19716687%26dopt%3DAbstract This study concludes that the epithelial-mesenchymal transformation does not occur in Hertwig's epithelial root sheath in rat acellular or cellular cementogenesis and that the dental follicle is the origin of cementoblasts, as has been proposed in the original hypothesis. PMID: 19716687 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2752695 Wed, 12 Aug 2009 23:00:00 +0100 2752695 http://www.medworm.com/index.php?rid=2692274&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19664913%26dopt%3DAbstract Authors: Schneider T, Cremer D, Becker C, Hansen ES, Bünger C, Drescher W An episode of ischemia followed by reperfusion of the femoral head (FH) is thought to be a common pathway in the pathogenesis of femoral head necrosis (FHN). Femoral head histology was investigated after short-term high-dose steroid treatment and femoral head ischemia and reperfusion in a large animal model. Twenty-two pigs were randomized to receive methylprednisolone 20mg/day/kg bodyweight intamuscularly for 3 days followed by methylprednisolone 10mg/day/kg bodyweight for 11 days (n=11), whereas the control group (n=11) received no treatment. After 6h of unilateral hip-joint pressure increase to 250mmHg, the pressure was discontinued and reperfusion was allowed for 4h. Undecalcified histology was performed... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2692274 Fri, 24 Jul 2009 23:00:00 +0100 2692274 http://www.medworm.com/index.php?rid=2630427&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19619994%26dopt%3DAbstract This study was aimed to elucidate the relation between the papillar morphology and its putative functions. The GG was obtained from adult bovine stomachs (n=10) and subdivided into (1) proximal, (2) middle, (3) distal portion of the reticular groove (RG) and (4) the area of the reticulo-omasal sphincter (ROS). The specimens were processed for scanning electron microscopy and stereomicroscopy to analyze the density, shape and location of the papillae. Whereas the proximal portion of the RG was characterized by small (1.5mm), conically shaped, smooth papillae, the middle portion exhibited larger papillae (4mm) with sharp borders covered by keratin. Towards the ROS the papillae further increased in size (3-11mm) and showed compound or single processes resembling the shape of arrows, twisted h... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2630427 Fri, 03 Jul 2009 23:00:00 +0100 2630427 http://www.medworm.com/index.php?rid=2622332&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19615873%26dopt%3DAbstract Authors: Tonack S, Ramin N, Garimella S, Rao R, Seshagiri PB, Fischer B, Navarrete Santos A During preimplantation development, embryos of many species are known to express up to five isoforms of the facilitative glucose transporter proteins (GLUT). Development of hamster blastocysts is inhibited by glucose. We therefore investigated GLUT isoform and insulin receptor (IR) expression in hamster preimplantation embryos cultured in glucose-free medium from the 8-cell stage onwards. We show that GLUT1, 3 and 8 mRNA are constitutively expressed from the 8-cell to the blastocyst stage. The IR is expressed from the morula stage onwards. Messenger RNA of the insulin-responsive GLUT4 was not detected at any stage. GLUT1 and 3 were localised by immunocytochemistry. GLUT1 was expressed in both em... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2622332 Thu, 25 Jun 2009 23:00:00 +0100 2622332 http://www.medworm.com/index.php?rid=2557028&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19560325%26dopt%3DAbstract CONCLUSION: There is an increase in total nerve cross-sectional area of the radial nerve in elderly cases. There is no relationship of sympathetic content to age. Our study makes an attempt to build a normal data base for radial nerve which might be helpful during the application of diagnostic procedures. PMID: 19560325 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2557028 Fri, 12 Jun 2009 23:00:00 +0100 2557028 http://www.medworm.com/index.php?rid=2557029&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19559584%26dopt%3DAbstract Authors: Koning RI, Koster AJ During the last six decades electron microscopy (EM) has been essential to ultra-structural studies of the cell to understand the fundamentals of cellular morphology and processes underlying diseases. More recently, electron tomography (ET) has emerged as a novel approach able to provide three-dimensional (3D) information on cells and tissues at molecular level. Electron tomography is comparable to medical tomographic techniques like CAT, PET and MRI in the sense that it provides a 3D view of an object, yet it does so at a cellular scale and with nanometer resolution. Electron tomography has the unique ability to visualize molecular assemblies, cytoskeletal elements and organelles within cells. The three-dimensional perspective it provides has revised our ... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2557029 Mon, 08 Jun 2009 23:00:00 +0100 2557029 http://www.medworm.com/index.php?rid=2526090&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19541466%26dopt%3DAbstract CONCLUSION: This study demonstrates the necessity of approaching the investigation of patient microcirculation in different ways depending on sex or age. PMID: 19541466 [PubMed - as supplied by publisher] (Source: Annals of Anatomy) Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2526090 Mon, 08 Jun 2009 23:00:00 +0100 2526090 http://www.medworm.com/index.php?rid=2526094&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19540742%26dopt%3DAbstract Authors: Chen H, Yano R, Emura S, Shoumura S Based on a large homogeneous sample from a Japanese population, anatomic variations in the celiac trunk (CT) and the hepatic artery were studied. Previously we analyzed the branching mode of the CT in 450 Japanese cadavers. In order to maximize the database on the CT and hepatic artery, we examined the anatomy of these arteries in 524 cadavers, a total of 974 cases. A total of 89.8% of cases showed the classical trifurcation of the CT. The typical normal pattern of the CT and the hepatic artery was confirmed in 66.6% and 72.4% of the cadavers, respectively. Variant left and right hepatic arteries were observed in 11.0% and 4.9%, respectively. A variant anatomy involving both the left and right hepatic arteries was found in 1.5%. A common hep... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2526094 Fri, 05 Jun 2009 23:00:00 +0100 2526094 http://www.medworm.com/index.php?rid=2526092&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19541465%26dopt%3DAbstract Authors: Schulze-Tanzil G Cartilage injury remains a major challenge in orthopedic surgery due to the fact that articular cartilage has only a limited capacity for intrinsic healing. Cartilage impaction is followed by a post-traumatic inflammatory response. Chondrocytes and synoviocytes are activated to produce inflammatory mediators and degradative enzymes which can induce a progradient cartilage self-destruction finally leading to secondary osteoarthritis (OA). However, an anti-inflammatory compensatory response is also detectable in cartilage by up-regulation of anti-inflammatory cytokines, probably a temporary attempt by chondrocytes to restore cartilage homeostasis. Matrix-assisted autologous chondrocyte transplantation (MACT) is a suitable technique for improving the rate of repa... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2526092 Fri, 05 Jun 2009 23:00:00 +0100 2526092 http://www.medworm.com/index.php?rid=2526114&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19345566%26dopt%3DAbstract Authors: Lee IS, Lee EJ, Park JB, Baek SH, Oh CS, Lee SD, Kim YS, Bok GD, Hong JW, Lim DS, Shin MH, Seo M, Shin DH Recently, we examined one of the most perfectly preserved mummies of the Joseon Dynasty (1392-1910) ever found in Korea. The individual was an elderly man and a high-ranking general who had lived sometime during the 16th or 17th century in Korea. When computerized tomography (CT) radiographs were taken, a fracture line was observed on the left side of the mandible. A post-factum dissection also provided crucial clues to the cause of death. First of all, blood clots were still evident at the fracture site, indicating that the mandibular fracture had occurred just before death. Second, we also found feces exclusively in the sigmoid colon or rectum, but not in the stomach, sm... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2526114 Sun, 31 May 2009 23:00:00 +0100 2526114 http://www.medworm.com/index.php?rid=2526112&cid=s_36924_170_f&fid=36924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19403284%26dopt%3DAbstract Authors: Klusáková I, Dubový P Peripheral neuropathic pain (PNP) frequently occurs as a consequence of nerve injury and may differ depending upon the type of insult and the individual patient. Progress in our knowledge of PNP induction mechanisms depends upon the utilization of appropriate experimental models in rodents based on various types of peripheral nerve lesions. In this review, we draw attention to current knowledge on basic cellular and molecular events in various experimental models used to induce the PNP symptoms. Spontaneous ectopic activity of axotomized and non-axotomized primary sensory neurons, the bodies of which are located in the dorsal root ganglion (DRG), seems to be a key mechanism of PNP induction. The primary sensory neurons are directly affected... Annals of Anatomy journals http://www.medworm.com/rss/comments.php?id=2526112 Sun, 31 May 2009 23:00:00 +0100 2526112