MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Annals of General Psychiatry' source. Tue, 07 Feb 2012 09:35:40 +0100 http://www.medworm.com/index.php?rid=5626391&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F11%2F1%2F2 We previously reported a case in which steroid-induced psychosis was eliminated with risperidone treatment in a patient with polyarthritis nodosa (PN). In the present report, we longitudinally tracked the serum levels of brain-derived neurotrophic factor (BDNF). We found that corticosteroid lowered serum BDNF levels, and improvement of psychiatric symptoms was intact with the serum BDNF levels seen in the patients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5626391 Mon, 23 Jan 2012 05:00:00 +0100 5626391 http://www.medworm.com/index.php?rid=5570595&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F11%2F1%2F1 Conclusions: Only around one-quarter of our outpatient schizophrenic population met full remission criteria. Use of RLAI gave a better remission rate than achieved in standard care with routine treatment. Criteria for remission should take into account clinical course and functioning to support clinical care. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5570595 Thu, 05 Jan 2012 05:00:00 +0100 5570595 http://www.medworm.com/index.php?rid=5535606&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F33 Conclusions: The results of this study provide evidence, with limitations, for the short-term effectiveness of the implemented educational MHP program on an adult group of recipients-key agents in their community. Because interventions for strengthening positive opinions about mental illness and enhancing self-assessed health constitute priority aims of mental health promotion, it would be beneficial to further investigate the sustainability of the observed positive changes. In addition it would be useful to examine (a) the possible interplay between the two outcome measures, that is, the effect of opinions of recipients about mental health on their perceived health, and (b) the applicability of this intervention in individuals with different sociodemographic profiles. (Source: Annals of G... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5535606 Fri, 23 Dec 2011 05:00:00 +0100 5535606 http://www.medworm.com/index.php?rid=5484859&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F32 Conclusions: Our findings suggest the high prevalence of VE, together with high rates in most of the SCL-90-R dimensions with greater depression, somatization, obsessive-compulsiveness and anxiety in a Greek COPD group at various Global Initiative for Chronic Obstructive Lung Disease (GOLD) diagnostic criteria stages. The coexistence of such symptoms should be further assessed as an eventual unfavorable prognostic factor. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5484859 Tue, 06 Dec 2011 05:00:00 +0100 5484859 http://www.medworm.com/index.php?rid=5438960&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F31 Conclusions: Humor appreciation, based on captionless cartoons in OCD, does not seem to be deficient compared to healthy subjects but may be related to illness characteristics. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5438960 Mon, 21 Nov 2011 05:00:00 +0100 5438960 http://www.medworm.com/index.php?rid=5378550&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F30 In the present work, we report two cases of monozygotic twins who developed prolonged apnea during electroconvulsive therapy (ECT) as a complication of anesthesia. In both cases, prolonged action of succinylcholine caused by a butyrylcholinesterase (BCHE) deficiency was confirmed by means of the dibucaine number test. In both cases, genetic analysis using the polymerase chain reaction revealed haplotype combined A and K variant mutations of the BCHE gene, both in the heterozygous form. These data show the potential risk of BCHE deficiency as a complication of anesthesia during ECT, and in particular underline the possible genetic contribution within a complex pathogenetic model. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5378550 Thu, 03 Nov 2011 04:00:00 +0100 5378550 http://www.medworm.com/index.php?rid=5356984&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F29 Conclusions: A major limitation of the present study is the small sample size that may reduce the generalizability of the results. Moreover, lifetime MOODS-SR does not provide information about the temporal sequence of the manic or depressive symptoms and the loss. The frequent comorbidity with MD and the association with both depressive and manic lifetime symptoms do not support the independence of CG from mood disorders. In our patients, CG is associated with high levels of separation anxiety in adulthood. However, the presence of lifetime mood instability, as measured by the frequent presence of depressive and hypomanic lifetime symptoms, suggests that cyclothymia might represent the common underlying feature characterizing the vulnerability to both adult separation anxiety and CG. (Sou... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5356984 Thu, 27 Oct 2011 04:00:00 +0100 5356984 http://www.medworm.com/index.php?rid=5332950&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F28 Conclusions: Medical healthcare workers appear to suffer from psychological distress more than their colleagues in the mental sector. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5332950 Wed, 19 Oct 2011 04:00:00 +0100 5332950 http://www.medworm.com/index.php?rid=5271273&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F27 Conclusions: Hearing impairment is common among older people and is associated with cognitive impairment, apathy and a poor health-related quality of life. Screening for and correcting hearing impairments might improve the quality of life and functional status of older patients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5271273 Sat, 01 Oct 2011 04:00:00 +0100 5271273 http://www.medworm.com/index.php?rid=5271276&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F24 Conclusions: It is possible that the increase in antidepressant prescribing might be associated with earlier treatment of depression, thus decreasing the likelihood of aggravation of depression. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5271276 Fri, 30 Sep 2011 04:00:00 +0100 5271276 http://www.medworm.com/index.php?rid=5271275&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F25 Attention deficit hyperactivity disorder (ADHD) is the most commonly diagnosed neurobehavioural disorder in childhood, affecting over 5% of children worldwide. As well as the core symptoms of inattention, hyperactivity and impulsivity, patients often exhibit learning difficulties and impairment in social functioning. The frequency of referral is higher for boys than for girls (about 2:1), and girls are generally older at the time of referral.Pharmacological therapy is considered the first-line treatment for patients with severe ADHD and severe impairment. Stimulant medications are licensed in the UK for the management of ADHD in school-age children and young people, and are effective in controlling ADHD symptoms.While immediate-release preparations of methylphenidate (MPH) have proven effe... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5271275 Fri, 30 Sep 2011 04:00:00 +0100 5271275 http://www.medworm.com/index.php?rid=5271274&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F26 Conclusion: Fluvoxamine, a sigma-1 receptor agonist, may be effective in preventing patients at UHR of psychotic disorder from onset of psychosis via its neuroprotective/neurotropic actions, independent of its antidepressive effects. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5271274 Fri, 30 Sep 2011 04:00:00 +0100 5271274 http://www.medworm.com/index.php?rid=5235604&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F22 Awareness of the importance of maintaining physical health for patients with severe mental illnesses has recently been on the increase. Although there are several elements contributing to poor physical health among these patients as compared with the general population, risk factors for cardiovascular disease such as smoking, diabetes mellitus, hypertension, dyslipidemia, metabolic syndrome, and obesity are of particular significance due to their relationship with mortality and morbidity. These patients present higher vulnerability to cardiovascular risk factors based on several issues, such as genetic predisposition to certain pathologies, poor eating habits and sedentary lifestyles, high proportions of smokers and drug abusers, less access to regular health care services, and potential a... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5235604 Mon, 19 Sep 2011 04:00:00 +0100 5235604 http://www.medworm.com/index.php?rid=5235603&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F23 Conclusions: Although only a preliminary study due to strong methodological limitations, and thus requiring confirmation by further controlled investigations, the current results indicate zonisamide may be a potential augmentation option for some depressed patients receiving low doses of duloxetine. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5235603 Mon, 19 Sep 2011 04:00:00 +0100 5235603 http://www.medworm.com/index.php?rid=5220896&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F21 Conclusions: Outpatients with schizophrenia or schizoaffective disorder in Japan had a high prevalence of MetS compared to inpatients. MetS in schizophrenic outpatients should be carefully monitored to minimize the risks. A change of lifestyle might improve MetS in schizophrenic patients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5220896 Mon, 12 Sep 2011 04:00:00 +0100 5220896 http://www.medworm.com/index.php?rid=5158405&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F20 Conclusions: There is a high prevalence of cognitive impairment among HD patients that has adverse implications for hospitalization and shortens their life expectancy. HD treatment was an independent risk factor for cognitive impairment. Clinicians should carefully monitor and treat cognitive impairment in HD patients. Further studies are required to determine the reasons for cognitive impairment in HD patients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5158405 Wed, 24 Aug 2011 23:00:00 +0100 5158405 http://www.medworm.com/index.php?rid=5019097&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F19 DiscussionThe SCCT seems to be a reliable, valid and sensitive to change instrument for the testing of psychiatric patients. The great advantage of this instrument is the fact that it only requires paper and a pencil, and is this easily administered and brief. Further research is necessary to test its usefulness as a neuropsychological test. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=5019097 Sun, 10 Jul 2011 23:00:00 +0100 5019097 http://www.medworm.com/index.php?rid=4828634&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F17 Conclusions: Heroin-dependent patients with psychiatric comorbidities may benefit from opioid agonist treatment not only because it targets their addictive problem, but also, precisely due to this, because it is effective against their mental disorder too. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4828634 Sat, 14 May 2011 23:00:00 +0100 4828634 http://www.medworm.com/index.php?rid=4788914&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F16 Background: Anorexia nervosa carries the highest mortality rate of any psychiatric disorder. Even the most critically ill anorexic patients may present with normal 'standard' laboratory values, underscoring the need for a new sensitive biomarker. The complement cascade, a major component of innate immunity, represents a driving force in the pathophysiology of multiple inflammatory disorders. The role of complement in anorexia nervosa remains poorly understood. The present study was designed to evaluate the role of complement C3 levels, the extent of complement activation and of complement hemolytic activity in serum, as potential new biomarkers for the severity of anorexia nervosa.Patients and methods: This was a prospective cohort study on 14 patients with severe anorexia nervosa, as defi... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4788914 Tue, 03 May 2011 23:00:00 +0100 4788914 http://www.medworm.com/index.php?rid=4723532&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F14 Videoconferencing has become an increasingly viable tool in psychiatry, with a growing body of literature on its use with a range of patient populations. A number of factors make it particularly well suited for patients with psychosis. For example, patients living in remote or underserved areas can be seen by a specialist without need for travel. However, the hallmark symptoms of psychotic disorders might lead one to question the feasibility of videoconferencing with these patients. For example, does videoconferencing exacerbate delusions, such as paranoia or delusions of reference? Are acutely psychotic patients willing to be interviewed remotely by videoconferencing? To address these and other issues, we conducted an extensive review of Medline, PsychINFO, and the Telemedicine Informatio... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4723532 Sun, 17 Apr 2011 23:00:00 +0100 4723532 http://www.medworm.com/index.php?rid=4704412&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F13 DiscussionThe SCPT seems to be a satisfactory, reliable and valid instrument, which is easy to administer, suitable for use in non-organic psychiatric patients and demands minimal time. Further research is necessary to test its psychometric properties and its usefulness and applications as a neuropsychological test. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4704412 Sun, 10 Apr 2011 23:00:00 +0100 4704412 http://www.medworm.com/index.php?rid=4696511&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F12 Background: This post hoc analysis (trial registration: ClinicalTrials.gov NCT00590577) assessed onset of efficacy and tolerability of acute treatment with once-monthly paliperidone palmitate (PP), a long-acting atypical antipsychotic initiated by day 1 and day 8 injections, in a markedly to severely ill schizophrenia population. Methods: Subjects entering the 13-week, double-blind trial were randomized to PP (39, 156, or 234 mg [25, 100, and 150 mg eq of paliperidone, respectively]) or placebo. This subgroup analysis included those with a baseline Clinical Global Impressions-Severity (CGI-S) score indicating marked to severe illness. PP subjects received a 234-mg day 1 injection (deltoid), followed by their assigned dose on day 8 and monthly thereafter (deltoid or gluteal). Thus, data for... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4696511 Sun, 10 Apr 2011 23:00:00 +0100 4696511 http://www.medworm.com/index.php?rid=4693117&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F11 Conclusions: The consensus regarding hospitalization for assessment and its associated problems were clarified. The consensus should be widely publicized among practitioners to ensure better management during the hospitalization of mentally disordered offenders for assessment. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4693117 Thu, 07 Apr 2011 23:00:00 +0100 4693117 http://www.medworm.com/index.php?rid=4631358&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F8 Conclusions: The available data suggest that a 'class effect' is the exception rather than the rule in the treatment of BD. However, the possible presence of a 'class effect' concept discourages clinicians from continued scientific training and reading. Focused educational intervention might be necessary to change this attitude. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4631358 Thu, 24 Mar 2011 00:00:00 +0100 4631358 http://www.medworm.com/index.php?rid=4591898&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F7 Conclusions: These results suggest that there is still room for improvement in the medical management of patients with GAD treated in psychiatric clinics. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4591898 Mon, 14 Mar 2011 00:00:00 +0100 4591898 http://www.medworm.com/index.php?rid=4574938&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F6 Background: Perception of quality of life may differ depending on the perspective. The aim of the study was to assess the psychometric properties of the Spanish version of the 'TOlerability and quality Of Life' (TOOL) questionnaire, a specific self-rated instrument to evaluate the impact of side effects of antipsychotic drugs on health-related quality of life (HRQoL). The questionnaire consists of eight items answered on a four-point Likert scale. Methods: A psychometric study was conducted with clinically stable outpatients with schizophrenia and bipolar disorder under antipsychotic treatment. The translation and cultural adaptation of the questionnaire was performed according to international standards. Internal consistency using the Cronbach alpha coefficient and test-retest reliability... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4574938 Fri, 11 Mar 2011 00:00:00 +0100 4574938 http://www.medworm.com/index.php?rid=4532061&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F5 Conclusions: Although clinical confounding factors (subthreshold bipolarity and eventually the presence of impaired circadian rhythms) and methodological boundaries (lack of control and neurophysiological recording, tiny sample size and short follow-up) limit the validity of this preliminary observation, it does indicate agomelatine may have a role in some SRI-refractory OCD cases, thus prompting the validity of investigation by further controlled studies, even for drug-naive OCD patients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4532061 Mon, 28 Feb 2011 00:00:00 +0100 4532061 http://www.medworm.com/index.php?rid=4517068&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F4 Conclusions: In our unit, clinicians prefer the combined antipsychotic/benzodiazepine regimen for the management of patients' acute agitation and violent behaviour. Conventional antipsychotics are administrated almost exclusively and in a significant proportion of cases further coercive measures are applied. Studies on the practice of chemical restraint should be regularly performed in clinical settings. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4517068 Thu, 24 Feb 2011 00:00:00 +0100 4517068 http://www.medworm.com/index.php?rid=4455128&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F3 Conclusions: In this study, we have demonstrated the potential of deep TMS treatment over the temporoparietal cortex as an add-on treatment for chronic auditory hallucinations in schizophrenic patients. Larger samples in a double-blind sham-controlled design are now being preformed to evaluate the effectiveness of deep TMS treatment for auditory hallucinations.Trial registration:This trial is registered with clinicaltrials.gov (identifier: NCT00564096). (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4455128 Wed, 09 Feb 2011 00:00:00 +0100 4455128 http://www.medworm.com/index.php?rid=4377435&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F10%2F1%2F2 Conclusions: Few studies have dealt specifically with guidelines for rating GAF. Current guidelines for rating GAF are not comprehensive, and relevant points for new guidelines are presented. Theoretical and empirical studies, and international expert panels would be valuable, as well as production of a manual with more information about scoring. Computerised assessment may well be the future. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4377435 Thu, 20 Jan 2011 00:00:00 +0100 4377435 http://www.medworm.com/index.php?rid=4285095&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F40 Conclusions: More studies including other eating disorder categories and recovered people are needed to explore important questions regarding the role of the intelligence quotient in treatment response. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4285095 Thu, 23 Dec 2010 00:00:00 +0100 4285095 http://www.medworm.com/index.php?rid=4248949&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F39 We present the case of a PI-OCD patient who developed severe nausea after response to off-label doses of the selective serotonin reuptake inhibitor (SSRI), fluoxetine. Drug choices are discussed, providing pharmacodynamic rationales and hypotheses along with reports of rating scale scores, administered within a follow-up period of 52 weeks. A slight reduction of fluoxetine dose, augmentation with mirtazapine and a switch from amisulpride to olanzapine led to resolution of nausea while preserving the anti-OCD therapeutic effect. Mirtazapine and olanzapine have already been suggested for OCD treatment, although a lack of evidence exists about their role in the course of PI-OCD. Both mirtazapine and olanzapine also act as 5-hydroxytryptamine receptor type 3 (5-HT3) blockers, making them prefe... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4248949 Fri, 10 Dec 2010 00:00:00 +0100 4248949 http://www.medworm.com/index.php?rid=4200480&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F38 Conclusions: Our data indicate the involvement of both hemispheres when affective states, and associated startle modulations, are produced, using materials with both audio and visual properties. From a methodological viewpoint, the robustness of film clip material including audio properties might compensate for the insufficient information reaching the ipsilateral hemisphere when using static pictures. From a theoretical viewpoint, a right ear advantage for verbal processing may account for the failure to detect the expected hemispheric difference. The verbal component of the clips would have activated the left hemisphere, possibly resulting in an increased role for the left hemisphere in both positive and negative affect generation. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4200480 Thu, 25 Nov 2010 00:00:00 +0100 4200480 http://www.medworm.com/index.php?rid=4133356&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F37 Conclusions: The results indicate that acute administration of ethyl loflazepate induces less effect on P300 latency than etizolam. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4133356 Wed, 03 Nov 2010 00:00:00 +0100 4133356 http://www.medworm.com/index.php?rid=4097485&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F36 Background: The purpose of this study was to investigate the variations of paraoxonase activity and lipid profile in bipolar I patients, and the association of this activity with the sociodemographic, clinical and therapeutic characteristics of this population.Patients and methods:Our study included 66 patients with bipolar I disorder and 64 controls aged 37.9 +/- 12.6 and 36.3 +/- 18.2 years, respectively. Paraoxonase activity was determined by kinetic methods; high-density lipoprotein cholesterol (c-HDL), low-density lipoprotein cholesterol (c-LDL), triglycerides and total cholesterol were determined by enzymatic methods; apolipoprotein (Apo)A1, ApoB and lipoprotein (a) (Lp(a)) were determined by immunoturbidimetry using Konelab 30 equipment (Thermo Scientific). Results: Compared with co... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=4097485 Wed, 20 Oct 2010 23:00:00 +0100 4097485 http://www.medworm.com/index.php?rid=3993461&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com Conclusions: Although the discontinuation rate was high, aripiprazole was found to be effective, safe and well tolerated in the long-term treatment of Taiwanese patients with schizophrenia who continued to receive treatment for 64 weeks. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3993461 Thu, 16 Sep 2010 23:00:00 +0100 3993461 http://www.medworm.com/index.php?rid=3938239&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F34 Conclusions: Comorbidities, the lack of religious practice, not having visitors and eating disorders are significant risk factors for depression, while age is a protective factor, among incarcerated women. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3938239 Sun, 05 Sep 2010 23:00:00 +0100 3938239 http://www.medworm.com/index.php?rid=3798435&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F33 Background: Factors Influencing Depression Endpoints Research (FINDER) is a 6-month, prospective, observational study carried out in 12 European countries aimed at investigating health-related quality of life (HRQoL) in outpatients receiving treatment for a first or new depressive episode. The Italian HRQoL data at 6 months is described in this report, and the factors associated with HRQoL changes were determined. Methods: Data were collected at baseline, 3 and 6 months of treatment. HRQoL was measured using components of the 36-item Short Form Health Survey (SF-36; mental component summary (MCS), physical component summary (PCS)) and the European Quality of Life-5 Dimensions (EQ-5D; visual analogue scale (VAS) and health status index (HSI)). The Hospital Anxiety and Depression Scale (HADS... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3798435 Wed, 28 Jul 2010 23:00:00 +0100 3798435 http://www.medworm.com/index.php?rid=3776205&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F32 Conclusions: The lifespan gender differences indicate the importance of including reproductive factors and social responsibilities in the understanding of the development of PTSD. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3776205 Tue, 20 Jul 2010 23:00:00 +0100 3776205 http://www.medworm.com/index.php?rid=3729744&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F31 Conclusions: Further research is needed in the areas of neuroendocrinological associations of violent behaviour, taxonomic existence of psychopathy and efficacy of treatment modalities. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3729744 Mon, 05 Jul 2010 23:00:00 +0100 3729744 http://www.medworm.com/index.php?rid=3726509&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F30 Conclusions: Even though preliminary, the present data show that VR is more effective than PH in eliciting emotional responses similar to those expected in real life situations. More generally, the present study suggests the potential of VR in a variety of experimental, training and clinical contexts, being its range of possibilities extremely wide and customizable. In particular, in a psychological perspective based on a cognitive behavioral approach, the use of VR enables the provision of specific contexts to help patients to cope with their diseases thanks to an easily controlled stimulation. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3726509 Sun, 04 Jul 2010 23:00:00 +0100 3726509 http://www.medworm.com/index.php?rid=3690716&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F27 Conclusions: This first randomised, double-blind, placebo-controlled trial supports the safety and efficacy of adjunctive tropisetron for treatment of cognitive deficits in schizophrenia. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3690716 Wed, 23 Jun 2010 23:00:00 +0100 3690716 http://www.medworm.com/index.php?rid=3690715&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F28 Conclusions: Doctors should consider fluvoxamine as an alternative approach to treating postoperative delirium in older patients in order to avoid the risk of side effects and increased mortality by antipsychotic drugs. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3690715 Wed, 23 Jun 2010 23:00:00 +0100 3690715 http://www.medworm.com/index.php?rid=3652266&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F26 Conclusions: Hospitals' and municipalities' self-reported provision of aftercare services for patients treated after a suicide attempt was markedly below the recommendations given in national standards. Systems at the hospital level for the management and care of patients admitted after a suicide attempt and systematic collaboration between hospitals and aftercare providers seem to be important elements in the long-term maintenance of continuity of care for suicide attempters. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3652266 Thu, 10 Jun 2010 23:00:00 +0100 3652266 http://www.medworm.com/index.php?rid=3625306&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F25 The biomolecular approach to major depression disorder is explained by the different steps that involve cell membrane viscosity, Gsalpha protein and tubulin. For the first time it is hypothesised that a biomolecular pathway exists, moving from cell membrane viscosity through Gsalpha protein and Tubulin, which can condition the conscious state and is measurable by electroencephalogram study of the brain's gamma wave synchrony. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3625306 Wed, 02 Jun 2010 23:00:00 +0100 3625306 http://www.medworm.com/index.php?rid=3621517&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F24 Background: The purpose of this analysis was to evaluate relationships between hospital admission or discharge and scores for symptom or functioning in patients with schizophrenia. Methods: Data were from three 52-week open-label extensions of the double-blind pivotal trials of paliperidone extended-release (ER). Symptoms and patient function were measured every 4 weeks using the Personal and Social Performance (PSP) scale and the Positive and Negative Syndrome Scale (PANSS). The intent-to-treat analysis set was defined as open-label patients who had at least one post-baseline PSP and PANSS measurement. Time until first hospitalization was evaluated using the Cox proportional hazard model with categorical time-dependent measures for the PSP (1 to 30, 31 to 70, 71 to 100) or PANSS ( (Source... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3621517 Tue, 01 Jun 2010 23:00:00 +0100 3621517 http://www.medworm.com/index.php?rid=3585400&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F23 Conclusion: Doctors should consider the monotherapy of sigma-1 receptor agonist fluvoxamine as an alternative approach to treating psychotic major depression. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3585400 Thu, 20 May 2010 23:00:00 +0100 3585400 http://www.medworm.com/index.php?rid=3542437&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F20 Conclusions: In the history of GAF, its basic properties have undergone limited changes. Problems with GAF may, in part, be due to lack of a research programme testing the effects of different changes in basic properties. Given the widespread use, research-based development of GAF has not been especially strong. Further research could improve GAF. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3542437 Thu, 06 May 2010 23:00:00 +0100 3542437 http://www.medworm.com/index.php?rid=3507995&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F19 Conclusions: The discussion envisions further steps to ascertain that this broad reduction of symptoms ensues from the singular correction that distinguishes the experimental intervention.Trial registrationProtocol Registration System NCT00269139. The PRS URL is https://register.clinicaltrials.gov (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3507995 Mon, 26 Apr 2010 23:00:00 +0100 3507995 http://www.medworm.com/index.php?rid=3467601&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F16 Background: Chronic obstructive pulmonary disease (COPD) is a major health problem, especially in adults over 40 years of age, and has a great social and economic impact. The psychological morbidity of COPD patients with regard to anxiety and depressive symptoms has been extensively studied in the past. However, few studies have investigated the prevalence of alexithymia in these patients, as well as its association with this comorbidity. Based on this fact, we studied the prevalence of alexithymia and its association with anxiety and depressive symptoms in COPD outpatients. Methods: The present study included 167, randomly selected, outpatients diagnosed with COPD. Alexithymia, anxiety and depression were assessed using the Toronto Alexithymia Scale (TAS-20), Spielberger Trait Anxiety Inv... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3467601 Tue, 13 Apr 2010 23:00:00 +0100 3467601 http://www.medworm.com/index.php?rid=3467602&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F15 Conclusions: This study supports the hypothesis that mood, anxiety and impulse-control dysregulation are the core of the clinical phenomenology of addiction and should be incorporated into its nosology. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3467602 Mon, 12 Apr 2010 23:00:00 +0100 3467602 http://www.medworm.com/index.php?rid=3463408&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F14 The present work represents a detailed description of our current understanding and knowledge of the epidemiology, etiopathogenesis and clinical manifestations of mood disorders, their comorbidity and overlap, and the effect of variables such as gender and age. This review article is largely based on the 'Mood disorders' chapter of the Wikibooks Textbook of Psychiatry (http://en.wikibooks.org/wiki/Textbook_of_Psychiatry/Mood_Disorders). (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3463408 Sun, 11 Apr 2010 23:00:00 +0100 3463408 http://www.medworm.com/index.php?rid=3460051&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F13 Panic disorder (PD) is characterised by sudden attacks of intense fear with somatic symptoms including palpitations and tachycardia. Reciprocally, palpitations caused by paroxysmal supraventricular tachycardia (PSVT) are commonly associated with anxiety and may therefore be misdiagnosed as PD. As demonstrated by two case reports, PSVT and PD can occur comorbidly in a chronological sequence, with PSVT possibly precipitating and maintaining PD via interoceptive processes or, alternatively, with PD increasing the risk for PSVT by elevating stress levels. As both PSVT and PD require different treatments, potentially helpful differential clinical diagnostic criteria are proposed. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3460051 Sun, 11 Apr 2010 23:00:00 +0100 3460051 http://www.medworm.com/index.php?rid=3429018&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F12 Psychiatric disorders in primary Sjogren's syndrome constitute a possible clinical reality that each practitioner must be able to recognise and treat. In this article, two case reports of mental disorder as clinical presentation of primary Sjogren's syndrome are presented, suggesting that psychiatric manifestations in primary Sjogren's syndrome can occur not only during its longitudinal course, but also at the onset of the autoimmune syndrome. A better adapted prescription of corticosteroids and/or immunosuppressive agents (together with specific psychotropic treatments) can induce rapid relief of mental symptoms. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3429018 Wed, 31 Mar 2010 23:00:00 +0100 3429018 http://www.medworm.com/index.php?rid=3338133&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F11 Conclusion: Doctors may wish to consider fluvoxamine as an alternative approach in treating akathisia associated with antipsychotic drugs such as aripiprazole. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3338133 Sat, 06 Mar 2010 00:00:00 +0100 3338133 http://www.medworm.com/index.php?rid=3311476&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F10 Conclusion: The present study did not identify the severity of residual sleep disturbance among fluoxetine responders to predict risk of MDD relapse. The size of our sample may have precluded us from identifying more modest effects of residual sleep disturbance on the risk of relapse in MDD patients. Future studies are needed to further explore the relationship between residual sleep disturbance and relapse in MDD.Trial registrationClinicalTrials.gov Identifier: NCT00427128 (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3311476 Fri, 26 Feb 2010 00:00:00 +0100 3311476 http://www.medworm.com/index.php?rid=3272731&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F9 Conclusions: Depressive disorder appears to be very common in orthopaedic outpatients in Pakistan; both social circumstances and nature of bone pathology are associated with such depression. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3272731 Mon, 15 Feb 2010 00:00:00 +0100 3272731 http://www.medworm.com/index.php?rid=3266803&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F7 Conclusion: On average 1 out of 10 of the patients had suicidal symptoms, more so in younger than the older people and in the more depressed. These symptoms had not been clinically recognised and therefore not managed. This calls for clinical practice that routinely enquires for suicidal symptoms in general medical wards. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3266803 Fri, 12 Feb 2010 00:00:00 +0100 3266803 http://www.medworm.com/index.php?rid=3189030&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F6 Conclusion: Doctors should consider that fluvoxamine could be an alternative approach in treating delirium in patients with Alzheimer's disease because of the risk of extrapyramidal side effects by antipsychotic drugs. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3189030 Wed, 20 Jan 2010 00:00:00 +0100 3189030 http://www.medworm.com/index.php?rid=3175766&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F4 Conclusions: The ability of the legal system to detect cases was good, while the ability of the healthcare system to predict crimes and offences was weak, as 58% of cases had had previous contact with the healthcare system previously. Substance abuse, especially amphetamine abuse, played an important role. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3175766 Thu, 14 Jan 2010 00:00:00 +0100 3175766 http://www.medworm.com/index.php?rid=3171736&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F3 Biological rhythms have always been considered to be disrupted in depression, with the predominant theory being that of hyperarousal. However, recent data suggest that it might be more appropriate to suggest that depressed patients are incapable of achieving and maintaining the particular level of internal homeostasis which permits them to function smoothly, to lower the level of arousal during sleep sufficiently so that quality of sleep is good, and to increase this level enough during the day so the person can function properly. Therefore, the transition from one state to another is somewhat problematic, delayed, incomplete and desynchronised. Thus, agents with a 'rhythm stabilising' effect could be beneficial in the treatment of mood disorders. Such an agent should have a beneficial eff... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3171736 Wed, 13 Jan 2010 00:00:00 +0100 3171736 http://www.medworm.com/index.php?rid=3145841&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F2 Conclusions: There has been a decline in the employment outcome of prevocational training during the current decade. This decline can be attributed to contextual adverse factors such as unemployment, a more demanding labour market and disability allowances offered by the state (the 'benefit trap'). Moreover, the training itself may be 'old-fashioned' enough, thus providing the trainees with inadequate skills to obtain and maintain a competitive job. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3145841 Wed, 06 Jan 2010 00:00:00 +0100 3145841 http://www.medworm.com/index.php?rid=3142402&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F9%2F1%2F1 Conclusions: The Greek translation of the SAST questionnaire is comparable with that of the original version in terms of reliability, and can be used in primary healthcare research. Its use in clinical practice should be primarily as a screening tool only at this stage, with a follow-up consisting of a detailed interview with the patient, in order to confirm the diagnosis. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3142402 Tue, 05 Jan 2010 00:00:00 +0100 3142402 http://www.medworm.com/index.php?rid=3133505&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F27 Conclusion: The data analysed for the current study support the usefulness of aripiprazole against psychotic symptoms during the acute manic and maintenance phases of bipolar illness. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3133505 Thu, 31 Dec 2009 00:00:00 +0100 3133505 http://www.medworm.com/index.php?rid=3108257&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F26 Conclusion: Doctors should consider fluvoxamine monotherapy as an alternative approach in treating psychotic depression because it avoids the risk of EPS from antipsychotic drugs. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=3108257 Mon, 21 Dec 2009 00:00:00 +0100 3108257 http://www.medworm.com/index.php?rid=2934538&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F25 Conclusions: Although prevalence rate for depression among children is high, detection rates remain low. This finding has clinical practice and policy implications within and outside Kenya. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2934538 Wed, 28 Oct 2009 00:00:00 +0100 2934538 http://www.medworm.com/index.php?rid=2886322&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F23 Conclusions: The findings of the study indicate that the Greek version of WHOQOL-100 provided satisfactory psychometric properties supporting its use within general and pathological populations and in the context of national and crosscultural QoL measurement. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2886322 Mon, 12 Oct 2009 23:00:00 +0100 2886322 http://www.medworm.com/index.php?rid=2871429&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F22 Conclusions: In the schizophrenic sample, anhedonia seems to be a specific subjective psychopathological experience of the negative and disorganised forms of schizophrenia. In the depressed sample, anhedonia seems to be a specific subjective psychopathological experience of those major depressive disorder forms with a marked clinical depression severity. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2871429 Wed, 07 Oct 2009 23:00:00 +0100 2871429 http://www.medworm.com/index.php?rid=2737562&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F20 Conclusions: The Greek SDQ could be potentially considered as a community-wide screening instrument for adolescents' emotional and behavioural problems. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2737562 Tue, 25 Aug 2009 23:00:00 +0100 2737562 http://www.medworm.com/index.php?rid=2724727&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F19 Background: In a few months from the time of this report, wards for inpatient care of psychiatric patients at the Bayero University Medical School Aminu Kano Teaching Hospital will be ready for admissions. The attitude of staff to the care of such patients within the hospital was the focus of this study. Methods: The investigation was a descriptive and cross-sectional study on a stratified and randomly selected sample population of workers at the Aminu Kano Teaching Hospital. A questionnaire was used to elicit responses from the respondents, containing 11 modified items. Statistical analysis of responses was performed. Results: The number of properly completed questionnaires analysed was 362. The result showed that 232 (64.1%) respondents would be fearful of having psychiatric patients adm... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2724727 Sat, 22 Aug 2009 23:00:00 +0100 2724727 http://www.medworm.com/index.php?rid=2648895&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F17 Conclusion: Family psychoeducation can be an important intervention for patients with schizophrenia in Pakistan. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2648895 Mon, 27 Jul 2009 23:00:00 +0100 2648895 http://www.medworm.com/index.php?rid=2645144&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F16 Conclusions: Aripiprazole appears effective for the treatment and prophylaxis against mania. The data on bipolar depression are so far negative, however there is a need for further study at lower dosages. The most frequent adverse effects are extrapyramidal signs and symptoms, especially akathisia, without any significant weight gain, hyperprolactinaemia or laboratory test changes. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2645144 Sun, 26 Jul 2009 23:00:00 +0100 2645144 http://www.medworm.com/index.php?rid=2509301&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F15 Correction to Geitona M, Kousoulakou H, Ollandezos M, Athanasakis K, Papanicolaou S and Kyriopoulos I: Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: a cost effectiveness study. Annals of General Psychiatry 2008, 7:16. This correction reports changes in the values listed for Ziprasidone and Aripiprazole in Table Ten. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2509301 Wed, 17 Jun 2009 23:00:00 +0100 2509301 http://www.medworm.com/index.php?rid=2446603&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F14 Background: Factors Influencing Depression Endpoints Research (FINDER) is a 6-month, prospective, observational study carried out in 12 European countries aimed at investigating health-related quality of life (HRQoL) in outpatients receiving pharmacological treatment for a first or new depressive episode. Baseline characteristics of patients enrolled in Italy are presented. Methods: All treatment decisions were at the discretion of the investigator. Data were collected at baseline and after 3 and 6 months of treatment. Baseline evaluations included demographics, medical and psychiatric history, and medications used in the last 24 months and prescribed at enrolment. The Hospital Anxiety and Depression Scale (HADS), was adopted to evaluate depressive symptoms, while somatic and painful physi... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2446603 Fri, 29 May 2009 04:00:00 +0100 2446603 http://www.medworm.com/index.php?rid=2416374&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F13 Our aim was to present a comprehensive, updated survey on obsessive-compulsive disorder (OCD) and obsessive-compulsive related disorders (OCRDs) and their clinical management via literature review, critical analysis and synthesis. Information on OCD and OCRD current nosography, clinical phenomenology and etiology, may lead to a better comprehension of their management. Clinicians should become familiar with the broad spectrum of OCD disorders, since it is a pivotal issue in current clinical psychiatry. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2416374 Mon, 18 May 2009 04:00:00 +0100 2416374 http://www.medworm.com/index.php?rid=2416375&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F12 Schizophrenia, a severe brain disorder that involves hallucinations, disordered thinking and deficiencies in cognition, has been studied for decades in order to determine the early events that lead to this neurological disorder. In this review, we interpret the developmental and genetic models that have been proposed and treatment options associated with these models. Schizophrenia was initially thought to be hereditary based on studies of high incidence in certain families. Additionally, studies on specific genes such as ZDHHC8 and DTNBP1 seem to suggest susceptibility to the onset of this disorder. However, no single gene variation has been linked to schizophrenia, and recent evidence on sporadic cases of schizophrenia refutes genetics as being a singular cause of the disease. In additio... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2416375 Fri, 15 May 2009 04:00:00 +0100 2416375 http://www.medworm.com/index.php?rid=2416377&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F10 Alcoholism is a chronic remitting and relapsing condition; its aetiology and pathophysiology remains largely obscure despite recent advances. This review summarises the current knowledge about the causation (biological or psychological) of alcohol addiction. This involves heredity, candidate genes, alcohol metabolism regulation and the influence of alcohol in the pathophysiology of the different neurotransmitter systems. Alcohol addiction is a multifactorial phenomenon where personality structure, individual state of mind and social influences are in constant interaction with brain neurobiology and pathophysiology. This disorder influences different sexes in different ways and causes major problems, especially in developed societies. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2416377 Thu, 14 May 2009 04:00:00 +0100 2416377 http://www.medworm.com/index.php?rid=2416376&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F11 Conclusions: The Greek version of AUDIT has increased internal reliability and validity. It detects 97% of the alcohol-dependent individuals and has a high sensitivity and specificity. AUDIT is easy to use, quick and reliable and can be very useful in detection alcohol problems in sensitive populations. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2416376 Thu, 14 May 2009 04:00:00 +0100 2416376 http://www.medworm.com/index.php?rid=2397837&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F9 Conclusions: Although losing more than 40% of the original items, the Japanese IPO may be a reliable and valid measure of Kernberg's personality organisation for Japanese populations. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2397837 Wed, 06 May 2009 04:00:00 +0100 2397837 http://www.medworm.com/index.php?rid=2197695&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F8 Conclusion: The majority of the medical students reported a negative impact of heavy workload on their psychological well-being. Significant numbers of medical students think that substance misuse is a coping strategy for stress. Teaching on addiction/addictive substances is poor at undergraduate level in Pakistani medical colleges. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2197695 Thu, 19 Feb 2009 05:00:00 +0100 2197695 http://www.medworm.com/index.php?rid=2197696&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F7 Conclusions: Patients with lower antipsychotic adherence were at greater risk of hospitalizations and ER visits. Thus, any efforts to increase adherence, even in small increments, can be helpful in decreasing these risks. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2197696 Wed, 18 Feb 2009 05:00:00 +0100 2197696 http://www.medworm.com/index.php?rid=2180115&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F6 Conclusions: In designing policies and programs to change negative opinions or beliefs of healthcare workers about childhood autism, there is a need for baseline information such as this survey. Changing the negative opinions or beliefs of the healthcare workers about childhood autism should encourage appropriate help-seeking behavior among parents of children with ASD who may be seeking advice or information from the healthcare workers. This would encourage early interventions, which are essential to prognosis of childhood autism. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2180115 Thu, 12 Feb 2009 05:00:00 +0100 2180115 http://www.medworm.com/index.php?rid=2127246&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F4 Conclusions: Although MADRS and CGI-I were more sensitive to treatment effects, HAM-D17, MADRS, CGI-S and CGI-I scores present a consistent picture of response to venlafaxine treatment. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2127246 Fri, 23 Jan 2009 05:00:00 +0100 2127246 http://www.medworm.com/index.php?rid=2118684&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F3 DiscussionThe Greek translation of the SWN-20 is reliable, with psychometric properties close to the original scale. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2118684 Wed, 21 Jan 2009 05:00:00 +0100 2118684 http://www.medworm.com/index.php?rid=2118685&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F2 Isotretinoin, a synthetic oral retinoid that is used against severe nodulocystic acne, has been associated with various psychiatric side effects such as depression, suicidality and psychotic symptoms. A great number of reports on its effects have been published since its introduction into the market. However, a causal relationship has not been established and the link between isotretinoin use and psychiatric events remains controversial. The present paper reviews the available evidence regarding the association of isotretinoin and psychiatric side effects. All published material reporting psychiatric side effects following isotretinoin treatment, including case reports, case series, reports from adverse drug event reporting systems, prospective surveys and retrospective case-control studie... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2118685 Tue, 20 Jan 2009 05:00:00 +0100 2118685 http://www.medworm.com/index.php?rid=2103277&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F8%2F1%2F1 Conclusions: The 4.1% clinician detection rate for mental disorders means that most psychiatric disorders in general medical facilities remain undiagnosed and thus, unmanaged. This calls for improved diagnostic practices in general medical facilities in Kenya and in other similar countries. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2103277 Wed, 14 Jan 2009 05:00:00 +0100 2103277 http://www.medworm.com/index.php?rid=2057963&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F26 Conclusions: Doctors should consider aripiprazole as a possible augmentation strategy for serotonergic poor responder obsessive-compulsive patients, but further research on these subjects is needed. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2057963 Tue, 23 Dec 2008 05:00:00 +0100 2057963 http://www.medworm.com/index.php?rid=2057962&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F27 Conclusions: In conclusion, the demonstration of an inverse relationship between infusion time of a fixed and convulsive dose of bupropion and the risk of convulsions in a prospective study is novel. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2057962 Tue, 23 Dec 2008 05:00:00 +0100 2057962 http://www.medworm.com/index.php?rid=2057964&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F25 Conclusions: Our findings of regional volume alterations of GM and WM in EOS patients coincide with those of previous studies of adult onset schizophrenia patients. However, in brain regions that had no overall structural differences between EOS patients and controls (that is, the bilateral posterior cingulate gyrus, the right thalamus, the cerebellum, and the pons), within-subject analysis of EOS patients alone revealed that there were significant associations of the volume in these areas and the symptom severity. These findings suggest that at an early stage of the illness, especially for those with onset before brain maturation, a wide range of disturbed neural circuits, including these brain regions that show no apparent morphological changes, may contribute to the formation of the sym... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=2057964 Mon, 22 Dec 2008 05:00:00 +0100 2057964 http://www.medworm.com/index.php?rid=1966533&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F24 Conclusions: Gender differences in the predictive value of social support on PTSD appear to be very complex, and no clear conclusions can be made based on the two studies included in this article. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1966533 Tue, 18 Nov 2008 05:00:00 +0100 1966533 http://www.medworm.com/index.php?rid=1957931&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F22 DiscussionThe present study explored the pattern of cortisol response to dexamethasone suppression and suggested an alternative way of coding and interpreting the DST on the basis of whether the cortisol levels remain stable or increase vs decrease after the administration of cortisol. The results put forward a complex way of understanding the relationship of the DST results with clinical symptoms. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1957931 Thu, 13 Nov 2008 05:00:00 +0100 1957931 http://www.medworm.com/index.php?rid=1957930&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F23 Conclusions: Although the severity and outcome of panic-agoraphobic symptomatology appear to be similar in patients with and without lifetime bipolar comorbidity, the higher number of concomitant disorders in our PD patients with BP-II does indicate a greater complexity of the clinical picture in this naturalistic study. That such complexity does not seem to translate into poorer response and outcome in those with comorbid soft bipolarity probably reflects the fact that we had brought BP-II under control with mood stabilizers. We discuss the implications of our findings as further evidence for the existence of a distinct anxious-bipolar diathesis. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1957930 Thu, 13 Nov 2008 05:00:00 +0100 1957930 http://www.medworm.com/index.php?rid=1898615&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F21 Conclusions: Government guidelines are only partially being met. Reliance on communication by ED staff would leave a substantial proportion of patients discharged from the ED with no or minimal communication to primary care. Psychiatric services need to improve the rate of communication to the patient's GP following assessment. A national sample of National Health Service (NHS) trusts would establish if this is a problem elsewhere. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1898615 Thu, 23 Oct 2008 04:00:00 +0100 1898615 http://www.medworm.com/index.php?rid=1882340&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F20 Autism is characterized by impairments in social interaction, communicative capacity and behavioral flexibility. Some cognitive theories can be useful for finding a relationship between these irregularities and the biological mechanisms that may give rise to this disorder. Among such theories are mentalizing deficit, weak central coherence and executive dysfunction, but none of them has been able to explain all three diagnostic symptoms of autism. These cognitive disorders may be related among themselves by faulty learning, since several research studies have shown that the brains of autistic individuals have abnormalities in the cerebellum, which plays a role in procedural learning. In keeping with this view, one may postulate the possibility that declarative memory replaces faulty proced... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1882340 Fri, 17 Oct 2008 04:00:00 +0100 1882340 http://www.medworm.com/index.php?rid=1878086&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F19 Conclusions: The demonstration of the dose-dependent and metabolite-dependent convulsive effects of bupropion metabolites is a novelty. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1878086 Wed, 15 Oct 2008 04:00:00 +0100 1878086 http://www.medworm.com/index.php?rid=1849617&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F18 Conclusions: These preliminary findings of decreased activity in POCs indicate that this more homogeneous population of unaffected relatives share similar neural abnormalities with people with schizophrenia, suggesting that reduced BOLD activity in the attention network may be an intermediate marker for schizophrenia. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1849617 Fri, 03 Oct 2008 04:00:00 +0100 1849617 http://www.medworm.com/index.php?rid=1777775&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F17 Conclusions: Moderately disabled MS patients with elevated Hcy levels are particularly prone to develop depressive symptomatology. Further study is warranted in order to elucidate the prognostic and therapeutic implications of this novel finding. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1777775 Tue, 09 Sep 2008 04:00:00 +0100 1777775 http://www.medworm.com/index.php?rid=1737147&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F16 Conclusions: Treatment with paliperidone ER can lead to lower total cost and higher number of stable days in most of the cases examined. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1737147 Thu, 28 Aug 2008 04:00:00 +0100 1737147 http://www.medworm.com/index.php?rid=1732231&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F15 Conclusions: These results strengthen the view that stigma attached to mental illness is not limited to the general public; medical students are also part of the stigmatising world. There is, therefore, a need to incorporate issues concerning stigma and its reduction as a core component of the mental health curriculum of medical schools. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1732231 Mon, 25 Aug 2008 04:00:00 +0100 1732231 http://www.medworm.com/index.php?rid=1722104&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F14 Conclusions: The Greek version of the ECS showed good psychometric properties. It can be used to assess susceptibility to emotional contagion in correlation with psychopathological processes, mood and anxiety disorders primarily. The usefulness of the ECS in the fields of group psychotherapy and health psychology is also under consideration. Further investigation is needed in all these areas. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1722104 Thu, 21 Aug 2008 04:00:00 +0100 1722104 http://www.medworm.com/index.php?rid=1712716&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F13 Conclusions: A number of self-help interventions have promising evidence for reducing subthreshold depressive symptoms. Other forms of evidence such as expert consensus may be more appropriate for interventions that are not feasible to evaluate in randomised controlled trials. There needs to be evaluation of whether promotion to the public of effective self-help strategies for subthreshold depressive symptoms could delay or prevent onset of depressive illness, reduce functional impairment, and prevent progression to other undesirable outcomes such as harmful use of substances. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1712716 Tue, 19 Aug 2008 04:00:00 +0100 1712716 http://www.medworm.com/index.php?rid=1711195&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F11 Conclusions: These results show that in mice alcohol lowers the seizure threshold for bupropion-induced seizures. Clinical implications are firstly that there may be an increased risk of seizures in patients consuming alcohol, and secondly that formulations that can release bupropion more readily in alcohol may present additional risks to patients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1711195 Mon, 18 Aug 2008 04:00:00 +0100 1711195 http://www.medworm.com/index.php?rid=1711194&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F12 Conclusion: Pakistani patients are just as likely to put on weight during antipsychotic treatment as patients from other countries. Considering that this population already has a much higher prevalence of diabetes mellitus compared to the Western countries, the consequences of increased weight may be even more serious in terms of increased morbidity and mortality. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1711194 Mon, 18 Aug 2008 04:00:00 +0100 1711194 http://www.medworm.com/index.php?rid=1703525&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F10 Conclusions: The transfer of a patient to the psychiatric ward is a decision depending on multiple factors. Medical diagnoses do not seem to play a major role in the transfer to the psychiatric ward. From the psychiatric diagnosis, depressive and dysthymic disorders are the most common in the transferred population, whilst the transfer is influenced by social factors regarding the patient, the patient's behaviour, the conditions in the ward she/he is treated in and any recent occurrence(s) that increase the anxiety of the staff. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1703525 Thu, 14 Aug 2008 04:00:00 +0100 1703525 http://www.medworm.com/index.php?rid=1651016&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F9 Freud began his career as a neurologist studying the anatomy and physiology of the nervous system, but it was his later work in psychology that would secure his place in history. This paper draws attention to consistencies between physiological processes identified by modern clinical research and psychological processes described by Freud, with a special emphasis on his famous paper on depression entitled 'Mourning and melancholia'. Inspired by neuroimaging findings in depression and deep brain stimulation for treatment resistant depression, some preliminary physiological correlates are proposed for a number of key psychoanalytic processes. Specifically, activation of the subgenual cingulate is discussed in relation to repression and the default mode network is discussed in relation to the... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1651016 Thu, 24 Jul 2008 04:00:00 +0100 1651016 http://www.medworm.com/index.php?rid=1592608&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F8 Conclusion: This research identifies factors that are associated with weapon bearing among adolescents in the United States. These factors may be important in the design of interventions aimed at improving school safety and adolescent health. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1592608 Mon, 07 Jul 2008 04:00:00 +0100 1592608 http://www.medworm.com/index.php?rid=1459757&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F7 Conclusions: Depression and anxiety are very prevalent in patients with pulmonary disease, especially chronic disease. This may be a very important negative factor in patients' adaptation to the chronic course of their disease. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1459757 Wed, 21 May 2008 04:00:00 +0100 1459757 http://www.medworm.com/index.php?rid=1345369&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F6 Conclusion: We believe the results of this study will raise awareness among school health practitioners and administrators, paediatric psychiatrists and psychologists on the prevalence and correlates of bullying among adolescents in Beijing, China. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1345369 Wed, 02 Apr 2008 04:00:00 +0100 1345369 http://www.medworm.com/index.php?rid=1299321&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F5 Conclusion: Our results are in contrast with that of previous studies that concluded sleep duration is shorter in Asia than in Europe, that boys woke-up significantly later than girls, and that the frequency of sleep latency category was associated with gender and grade level. The magnitude of the daytime sleepiness, daytime sleepiness during classes, sleep latency, and incidences of waking up at night represent major public health concerns for Iran. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1299321 Thu, 13 Mar 2008 04:00:00 +0100 1299321 http://www.medworm.com/index.php?rid=1282812&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F4 Conclusions: The Greek version of HADS showed good psychometric properties and could serve as a useful tool for clinicians to assess anxiety and depression in general hospital patients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1282812 Thu, 06 Mar 2008 05:00:00 +0100 1282812 http://www.medworm.com/index.php?rid=1240762&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F3 Conclusion: Physicians should consider a comorbid hyperthyroidism in bipolar manic patients only partially responsive to standard care treatment with a mood stabilizer and antipsychotic. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1240762 Tue, 19 Feb 2008 05:00:00 +0100 1240762 http://www.medworm.com/index.php?rid=1187771&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F2 Conclusion: The present study failed to provide support for a season of birth effect on atypical lateralisation of handedness in humans. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1187771 Wed, 30 Jan 2008 05:00:00 +0100 1187771 http://www.medworm.com/index.php?rid=1174157&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F7%2F1%2F1 The family can play an important role in the prevention of suicide if it is capable of aiding the mental health care services in the early detection and management of family members at risk. In order to attain this goal, the whole family should be informed in how to prevent suicide. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1174157 Thu, 24 Jan 2008 05:00:00 +0100 1174157 http://www.medworm.com/index.php?rid=1098290&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F33 Conclusions: The concurrence of schizophrenia and Gaucher's disease in the same family is an unusual phenomenon. The literature regarding this coincidence is limited, despite the fact that patients with Gaucher's disease have one or two mutated alleles, considered to be a risk factor leading to conditions such as Dementia, Parkinson's disease and schizophrenia. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1098290 Mon, 17 Dec 2007 05:00:00 +0100 1098290 http://www.medworm.com/index.php?rid=1028903&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F32 Conclusion: Parents' opinions and beliefs are not in line with scientific facts. This suggests a need to further inform the parents on the safety and efficacy of psychotropic medication in order to improve treatment compliance. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1028903 Thu, 15 Nov 2007 05:00:00 +0100 1028903 http://www.medworm.com/index.php?rid=1023163&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F30 Conclusion: Further studies via nationally representative surveys need to be undertaken to fully grasp the scope of this emerging public health issue in Pakistan. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1023163 Tue, 13 Nov 2007 05:00:00 +0100 1023163 http://www.medworm.com/index.php?rid=1023162&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F31 Conclusions: The presence of depressive-anxious symptomatology in the clinical presentation in heroin addicts appears to be unrelated to 'dual diagnosis'. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1023162 Tue, 13 Nov 2007 05:00:00 +0100 1023162 http://www.medworm.com/index.php?rid=1003157&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F29 Conclusions: Results confirm the widespread use of antipsychotics and the increasing trend in atypical drugs prescription, in both psychiatric in- and outpatients. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=1003157 Mon, 05 Nov 2007 05:00:00 +0100 1003157 http://www.medworm.com/index.php?rid=988963&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F28 Conclusions: Our results confirm the prevailing view that depression and anxiety are common psychological disorders in epileptics. It is additionally concluded that female gender, high seizure frequency and a symptomatic epilepsy syndrome are independent risk factors for the development of anxiety and/or depression. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=988963 Tue, 30 Oct 2007 04:00:00 +0100 988963 http://www.medworm.com/index.php?rid=937734&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F27 Conclusions: The first-line psychosocial intervention in BD is psychoeducation, followed by cognitive-behavioral therapy. Other treatment options include Electroconvulsive therapy and transcranial magnetic stimulation. There is a gap between the evidence base, which comes mostly from monotherapy trials, and clinical practice, where complex treatment regimens are the rule. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=937734 Tue, 09 Oct 2007 04:00:00 +0100 937734 http://www.medworm.com/index.php?rid=933668&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F25 Conclusion: Despite the severe methodological limitations of case-reports in general, the present one suggests that OXC as monotherapy might be both safe and efficacious in the treatment of acute mania in patients with early-onset type-1 DM, whose already compromised physical condition constitutes an absolute or relative contra-indication for the administration of standard treatments, though there are no, as yet, large randomized clinical trials attesting to its efficacy unambiguously. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=933668 Mon, 08 Oct 2007 04:00:00 +0100 933668 http://www.medworm.com/index.php?rid=926858&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F24 Conclusions: Results showed that primary care patients will enroll, participate in and complete psychiatric research protocols using remote interviews conducted via videoconference. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=926858 Thu, 04 Oct 2007 04:00:00 +0100 926858 http://www.medworm.com/index.php?rid=842405&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F23 Epidemiological data suggest that between 59 and 87% of suicide victims suffered from major depression while up to 15% of these patients will eventually commit suicide. Male gender, previous suicide attempt(s), comorbid mental disorders, adverse life-situations, acute psycho-social stressors etc. also constitute robust risk factors. Anxiety and minor depression present with a low to moderate increase in suicide risk but anxiety-depression comorbidity increases this risk dramatically Contrary to the traditional psychoanalytic approach which considers suicide as a retrospective murder or an aggression turned in-wards, more recent studies suggest that the motivations to commit suicide may vary and are often too obscure. Neurobiological data suggest that low brain serotonin activity might play... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=842405 Wed, 05 Sep 2007 04:00:00 +0100 842405 http://www.medworm.com/index.php?rid=807107&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F22 Conclusions: These two case studies illustrate the feasibility of CBT for psychotic symptoms with intellectually disabled people, but need to be confirmed by more stringent studies. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=807107 Sun, 19 Aug 2007 04:00:00 +0100 807107 http://www.medworm.com/index.php?rid=790945&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F21 Conclusions: These results show that OVX-induced anxiety and changes in neuroimmunological function in the cortex are reversed by dioscorea treatment. Furthermore, individual differences need to be taken into account when psychoneuroimmunological issues are measured and the EPM is a useful tool for determining anxiety levels when examining anxiety-related issues. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=790945 Fri, 10 Aug 2007 04:00:00 +0100 790945 http://www.medworm.com/index.php?rid=775752&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F20 DiscussionThe current study is the first one in this area of research using modern and rigid diagnostic methodology and a biological marker (DST) to categorize patients. Its disadvantages are the lack of data concerning DST in controls and a relatively small size of patient sample. The results confirm the seasonality of birth rate of patients suffering from specific types of depression. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=775752 Fri, 03 Aug 2007 04:00:00 +0100 775752 http://www.medworm.com/index.php?rid=765214&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F19 Conclusions: The data suggests that persistent cognitive deficits are seen in patients with schizophrenia under remission. The cognitive deficits were not associated with symptomatology and functional disability. It is possible that various factors such as employment and family support reduce disability due to schizophrenia in developing countries like India. Further studies from developing countries are required to explore the relationship between cognitive deficits, functional outcome and the role of socio-cultural variables as protective factors. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=765214 Mon, 30 Jul 2007 04:00:00 +0100 765214 http://www.medworm.com/index.php?rid=754790&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F18 Conclusion: Prevalence of physical fighting within the last 12 months was comparable to estimates obtained in European countries. We also found clustering of problem behaviours or experiences among adolescents who reported having engaged in physical violence in the past 12 months. There is need to bring adolescent violent behaviours to the fore of the public health agenda in Namibia. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=754790 Tue, 24 Jul 2007 04:00:00 +0100 754790 http://www.medworm.com/index.php?rid=704852&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F17 Conclusions: The results of this study can be used as evidence for presenting religious counselling and spiritual interventions for individuals undergoing stress. Finally, based on the results of this study, the researcher suggested some recommendations for applying results and conducting further research. Key words: religiosity ,anxiety , Iran, surgery,correlational (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=704852 Fri, 29 Jun 2007 04:00:00 +0100 704852 http://www.medworm.com/index.php?rid=702385&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F16 Conclusions: It is difficult to be absolutely certain whether the lesion had influence on the patient's psychiatric symptoms or not. However, given the anatomical and neuropsychological changes, one cannot exclude the possibility that the lesion played a significant role in this psychiatric presentation. This raises substantial problems when it comes to choosing a therapeutic strategy. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=702385 Thu, 28 Jun 2007 04:00:00 +0100 702385 http://www.medworm.com/index.php?rid=663724&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F15 Dementia is a clinical state characterized by loss of function in multiple cognitive domains. It is a costly disease in terms of both personal suffering and economic loss. Frontotemporal dementia (FTD) is the term now preferred over Picks disease to describe the spectrum of non-Alzheimers dementias characterized by focal atrophy of the frontal and anterior temporal regions of the brain. The prevalence of FTD is considerable, though specific figures vary among different studies. It occurs usually in an age range of 35-75 and it is more common in individuals with a positive family history of dementia. The risk factors associated with this disorder include head injury and family history of FTD. Although there is some controversy regarding the further syndromatic subdivision of the different t... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=663724 Tue, 12 Jun 2007 04:00:00 +0100 663724 http://www.medworm.com/index.php?rid=663725&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F14 Conclusion: This exploratory study has produced encouraging data supporting the use of CRT in patients with AN: it has also provided insight into how the module should be tailored to maximise its effectiveness for people with acute AN. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=663725 Tue, 05 Jun 2007 04:00:00 +0100 663725 http://www.medworm.com/index.php?rid=560037&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F12 Conclusion: Traumatised patients appear to be under- or misdiagnosed which could have an impact on the efficiency of treatment. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=560037 Fri, 20 Apr 2007 04:00:00 +0100 560037 http://www.medworm.com/index.php?rid=518243&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F11 Conclusions: Although patients had greater severity of psychosis than clinical trial patients there were no unexpected findings. In addition the PANSS-EC scale is a scale that may be useful in assessing the efficacy of IM antipsychotics in any unit. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=518243 Sun, 01 Apr 2007 04:00:00 +0100 518243 http://www.medworm.com/index.php?rid=489359&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F10 Suicide is a major cause of death among patients with schizophrenia. Research indiactes that at least 5-13% of schizophrenic patients die by suicide, and it is likely that the higher end of range is the most accurate estimate. There is almost total agreement that the schizophrenic patient who is more likely to commit suicide is young, male, white and never married, with good premorbid function, post-psychotic depression and a history of substance abuse and suicide attempts. Hopelessness, social isolation, hospitalization, deteriorating health after a high level of premorbid functioning, recent loss or rejection, limited external support, and family stress or instability are risk factors for suicicde in patients with schizophrenia. Suicidal schizophrenics usually fear further mental deterio... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=489359 Fri, 16 Mar 2007 04:00:00 +0100 489359 http://www.medworm.com/index.php?rid=474147&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F9 Conclusions: These findings suggest that a depressotypic personality style is related to depressive disorder, but not to FMS. Trial registration: NCT00184106 (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=474147 Fri, 09 Mar 2007 05:00:00 +0100 474147 http://www.medworm.com/index.php?rid=445763&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F8 For the first time in history, psychiatrists during the Nazi era sought to systematically exterminate their patients. However, little has been published from this dark period analyzing what may be learned for clinical and research psychiatry. At each stage in the murderous process lay a series of unethical and heinous practices, with many psychiatrists demonstrating a profound commitment to the atrocities, playing central, pivotal roles critical to the success of Nazi policy. Several misconceptions led to this misconduct, including allowing philosophical constructs to define clinical practice, focusing exclusively on preventative medicine, allowing political pressures to influence practice, blurring the roles of clinicians and researchers, and falsely believing that good science and good e... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=445763 Tue, 27 Feb 2007 05:00:00 +0100 445763 http://www.medworm.com/index.php?rid=407484&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F5 Clinicians face everyday the complexity of depression. Available pharmacotherapies and psychotherapies improve patients suffering in a large part of subjects, however up to half of patients do not respond to treatment. Clinicians may forecast to a good extent if a given patient will respond or not, based on a number of data and sensations that emerge from face to face assessment. Conversely, clinical predictors of non response emerging from literature are largely unsatisfactory. Here we try to fill this gap, suggesting a comprehensive assessment of patients that may overcome the limitation of standardized assessments and detecting the factors that plausibly contribute to so marked differences in depressive disorders outcome. For this aim we present and discuss two clinical cases. Mr. A wa... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=407484 Wed, 07 Feb 2007 07:00:00 +0100 407484 http://www.medworm.com/index.php?rid=391734&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F4 Conclusions: Adults with ADHD were more likely than controls to collide with an obstacle during a driving simulation suggesting that deficits in directed attention may underlie driving impairments in this population. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=391734 Tue, 30 Jan 2007 07:00:00 +0100 391734 http://www.medworm.com/index.php?rid=391736&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F3 Conclusions: The relapse rate in this study was relatively low (similar to that reported with other long-acting antipsychotics) and clinically stable baseline status was maintained. While the results suggest that some symptomatically stable patients with schizophrenia or schizoaffective disorder might be safely managed with long-acting risperidone 50mg once monthly, these findings alone do not identify which patients will have a sufficient therapeutic benefit nor do they quantify comparative effects of standard and altered dosing. Controlled studies would be required to support a recommendation for alternative dosing regimens. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=391736 Mon, 29 Jan 2007 07:00:00 +0100 391736 http://www.medworm.com/index.php?rid=391737&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F2 Conclusion: patients with psychiatric diseases in acute phase experienced a satisfactory outcome following intensified therapeutic interventions during hospitalisation. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=391737 Sat, 27 Jan 2007 07:00:00 +0100 391737 http://www.medworm.com/index.php?rid=341380&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F6%2F1%2F1 Conclusions: To account for the FAS and agrammatism in FG, various explanations have been ruled out. Because of the focal deficit seen on the brain imaging, involving the left insular and anterior temporal cortex, two brain regions frequently involved in aphasic syndrome but also in FAS, a cerebrovascular origin must be considered the best explanation to account for FGs language deficits. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=341380 Thu, 04 Jan 2007 07:00:00 +0100 341380 http://www.medworm.com/index.php?rid=300072&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F5%2F1%2F20 The purpose of this case study was to use an evidence based medicine approach to work through an unusual way of treating a common problem. We looked at an example of an in-patient with severe refractory psychotic depression who had been resistant to treatment with a combination of antidepressant, antipsychotics, mood stabiliser, and concomitant ECT therapy. We then undertook a literature search for the use of clozapine in a patient with severe refractory depression. Although the resulting evidence was low level and thin, we felt on balance that a trial of clozapine was justified. We used a BPRS inventory to monitor her mood prior to commencing clozapine. Her mood and functional abilities were monitored as her clozapine was titrated upwards. Our patient showed a significant improvement in m... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=300072 Wed, 29 Nov 2006 07:00:00 +0100 300072 http://www.medworm.com/index.php?rid=300071&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F5%2F1%2F22 Conclusions: Although this small pilot study was unable to demonstrate a significant relationship between listening to oneself chewing and enjoyment of eating, other evidence suggests that distraction techniques have a beneficial effect on dietary intake. Such techniques can be applied in a clinical setting and further work in this area has valuable potential. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=300071 Wed, 29 Nov 2006 07:00:00 +0100 300071 http://www.medworm.com/index.php?rid=300073&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F5%2F1%2F19 We acquired diffusion tensor and structural MRI images on 103 patients with schizophrenia and 41 age-matched normal controls. The vector data was used to trace tracts from a region of interest in the anterior limb of the internal capsule to the prefrontal cortex. Patients with schizophrenia had tract paths that were significantly shorter in length from the center of internal capsule to prefrontal white matter. These tracts, the anterior thalamic radiations, are important in frontal-striatal-thalamic pathways. These results are consistent with findings of smaller size of the anterior limb of the internal capsule in patients with schizophrenia, diffusion tensor anisotropy decreases in frontal white matter in schizophrenia and hypothesized disruption of the frontal-striatal-thalamic pathway s... Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=300073 Tue, 28 Nov 2006 07:00:00 +0100 300073 http://www.medworm.com/index.php?rid=283307&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F5%2F1%2F17 Conclusions: Majority of cases of organophosphorus poisoning were associated with severe symptoms and higher lethality. Intervention facilities decreasing the period between the ingestion of poison and initiation of treatment might prevent many deaths. Measures like restricting availability and banning more toxic organophosphorus compounds may help. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=283307 Tue, 21 Nov 2006 07:00:00 +0100 283307 http://www.medworm.com/index.php?rid=283306&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F5%2F1%2F18 We report the case of a 32-year-old male patient with a five-year history of psychotic depression accompanied by paranoid delusions centered around his belief that his neighbors criticized him and stared at him. A central feature of his clinical picture was an eye injury that the patient had caused by pouring molten lead into his right eye during a period of deep hopelessness and suicidality when the patient could not resolve his anhedonia and social isolation. Pharmacotherapy and psychotherapy dramatically improved his disorder. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=283306 Tue, 21 Nov 2006 07:00:00 +0100 283306 http://www.medworm.com/index.php?rid=200323&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F5%2F1%2F15 Conclusion: This result may odds to the understanding of weight gain associated with antipsychotics and underscores the importance of assessing binge eating behaviour during treatment and prevention of obesity in this population. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=200323 Tue, 12 Sep 2006 06:00:00 +0100 200323 http://www.medworm.com/index.php?rid=146132&cid=s_27172_172_f&fid=27172&url=http%3A%2F%2Fwww.annals-general-psychiatry.com%2Fcontent%2F5%2F1%2F13 Discussion: Alexithymia may be important in addressing the diversity of subjective factors involved in pain. The conceptualization of alexithymia as a personality trait as well as a secondary state reaction is underlined by our data. (Source: Annals of General Psychiatry) Annals of General Psychiatry journals http://www.medworm.com/rss/comments.php?id=146132 Tue, 15 Aug 2006 06:00:00 +0100 146132