MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Archives of Oral Biology' source. Wed, 08 Feb 2012 12:06:11 +0100 http://www.medworm.com/index.php?rid=5638481&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002640%2Fabstract%3Frss%3Dyes Conclusions: These data suggest that patients with glossopyrosis not only differ clinically from those with oropyrosis but also exhibit magnesium deficiency as manifested by lower than normal magnesium levels in saliva and erythrocytes. Lingual burning in patients with glossopyrosis is consistent with hyperalgesia and neurogenic inflammation observed in patients and animals with magnesium deficiency and in magnesium deficient tissues. These results suggest a possible biochemical mechanism for pyrosis in patients with glossopyrosis. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638481 Sun, 29 Jan 2012 16:46:12 +0100 5638481 http://www.medworm.com/index.php?rid=5638480&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002676%2Fabstract%3Frss%3Dyes In this study, we determined the concentrations of SPLUNC1 in saliva using a particle-based antibody capture and detection immunoassay. A commercial goat anti-rhSPLUNC1 polyclonal antibody (AF1897) was linked to fluorescent polystyrene microspheres and used as the capture antibody. A commercial mouse IgG2b anti-rhSPLUNC1 monoclonal antibody (MAB1897) was biotinylated and used as the detection antibody. Western blot and 2-dimensional fluorescence difference gel electrophoresis (2-D DIGE) analysis of immunoprecipitated rhSPLUNC1 and SPLUNC1 from saliva were used to show that the capture AF1897 and detection MAB1897 antibodies both recognized SPLUNC1. Protein concentrations in saliva from 20 subjects ranged from 0.9 to 23.9mg/ml; SPLUNC1 concentrations ranged from 34.7ng/ml to 13.8μg/ml; and... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638480 Sun, 29 Jan 2012 16:46:12 +0100 5638480 http://www.medworm.com/index.php?rid=5638479&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100272X%2Fabstract%3Frss%3Dyes Abstract: Objective: Previous studies have suggested that some functional polymorphisms in the matrix metalloproteinase (MMPs) genes are associated with the risk of periodontal disease. However, to date no study has investigated MMP8 gene variants in relation to chronic periodontitis (CP). The aim of this study was to analyse polymorphisms in the MMP8 gene and their associations with microbial composition and clinical manifestation of CP.Design: A total of 619 unrelated Czech subjects were included in the present study. Two polymorphisms [−799C/T (rs11225395) and +17C/G (rs2155052)] in the MMP8 gene were studied in 341 patients with CP and 278 unrelated non-periodontitis controls. Both polymorphisms were detected using the polymerase chain reaction–restriction fragment length polymorph... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638479 Sun, 29 Jan 2012 16:46:12 +0100 5638479 http://www.medworm.com/index.php?rid=5638478&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002652%2Fabstract%3Frss%3Dyes Conclusion: Results indicate that BGNKO-mice exhibit significant differences in tissue properties compared to WT-mice. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638478 Sun, 29 Jan 2012 16:46:12 +0100 5638478 http://www.medworm.com/index.php?rid=5638477&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002627%2Fabstract%3Frss%3Dyes Conclusion: The periodontal ligament cell-sheets fabricated through normal cell culture dish has a potential for regeneration of periodontal ligament and may become a novel therapy for avulsed teeth replantation. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638477 Sun, 29 Jan 2012 16:46:12 +0100 5638477 http://www.medworm.com/index.php?rid=5638476&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002615%2Fabstract%3Frss%3Dyes Abstract: Objectives: There is controversial evidence regarding the levels of antioxidant molecules in type 2 diabetes periodontitis patients. Thus, the aim of the present study was to evaluate the gene expression of antioxidant enzymes in the gingival tissue of poorly and well-controlled type 2 diabetic subjects with chronic periodontitis (CP).Design: Gingival biopsies were harvested from systemically and periodontally healthy subjects (n=12), systemically healthy subjects with CP (n=15), well-controlled (n=8) and poorly controlled (n=14) diabetic subjects with CP. The messenger RNA (mRNA) levels of peroxiredoxin (PRDX) 1 and 2, catalase (CAT), glutathione peroxidase (GPX1) and superoxide dismutase (SOD) 1 and 2 were measured by quantitative polymerase chain reaction (qPCR).Results: The r... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638476 Sun, 29 Jan 2012 16:46:12 +0100 5638476 http://www.medworm.com/index.php?rid=5638475&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002718%2Fabstract%3Frss%3Dyes Conclusions: The main differences amongst CD children who did or did not comply with a gluten-free diet and control children are the presence of PMNs in oral mucosa and protein salivary patterns; these findings could be considered as markers for CD, in conjunction with other signs and symptoms. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638475 Sun, 29 Jan 2012 16:46:12 +0100 5638475 http://www.medworm.com/index.php?rid=5638474&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002706%2Fabstract%3Frss%3Dyes Abstract: It is widely accepted that tabagism is a predisposing factor to oral candidosis and cumulate data suggest that cigarette compounds may increase candidal virulence. To verify if enhanced virulence occurs in Candida albicans from chronic smokers, a cohort of 42 non-smokers and other of 58 smokers (all with excellent oral conditions and without signs of candidosis) were swabbed on tong dorsum and jugal mucosa. Results showed that oral candidal loads do not differ between smoker and non-smokers. Activities of secreted aspartyl-protease (Sap), phospholipase, chondroitinase, esterase–lipase, and haemolysin secretions were screened for thirty-two C. albicans isolates. There were detected significant increments in phospholipasic and chondroitinasic activities in isolates from non-smoke... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638474 Sun, 29 Jan 2012 16:46:12 +0100 5638474 http://www.medworm.com/index.php?rid=5638473&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002585%2Fabstract%3Frss%3Dyes Abstract: Objectives: In vitro biofilm models, representative of some aspects of nascent, supra-gingival plaques (Hydroxyapatite Disc Biofilm Models), developed supra-gingival plaques (Modified Drip-flow Biofilm Reactors) and sub-gingival plaques (Multiple Sorbarod Devices) were used to compare the antimicrobial effects of a triclosan-containing dentifrice with a stannous fluoride and zinc lactate combination.Design: Triplicate salivary biofilm microcosms were maintained for 2d (hydroxyapatite discs), 5d (Sorbarods) or up to 6d (drip flow reactors). Dentifrice slurries (10%, w/v) were added once to the discs and repeatedly to the Drip Flow Reactors and Sorbarods. Plaques were analysed by differential culture and gravimetrically.Results: Whilst both dentifrices were comparably effective at ... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638473 Sun, 29 Jan 2012 16:46:12 +0100 5638473 http://www.medworm.com/index.php?rid=5638472&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002639%2Fabstract%3Frss%3Dyes Abstract: Objectives: To characterize the mechanical and biological properties of a resin-modified glass ionomer cement (RMGIC) containing doxycycline hyclate.Methods: The antibacterial effect of RMGIC containing 1.5, 3.0 and 4.5% doxycycline hyclate was assessed using two experiments – agar diffusion test for 24h and biofilm assay for 24h and 7 days – against some cariogenic bacteria. Briefly, base layers of BHI agar and 300μL of each inoculum were prepared in Petri dishes with 6 wells that were completely filled with materials. After 24h incubation, zones of bacterial growth inhibition were measured using a digital caliper. Biofilm assays were conducted using RMGIC specimens immersed in 24-well plates containing the inoculum in BHI broth. After 24h and 7 days, each specimen were rem... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638472 Sun, 29 Jan 2012 16:46:12 +0100 5638472 http://www.medworm.com/index.php?rid=5638471&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002688%2Fabstract%3Frss%3Dyes Conclusions: The first standards of timing and sequence of permanent tooth emergence specific to the Jordanian population were provided and found to be consistent with those of Caucasian populations. These standards aid managing patients in paediatric dentistry, planning orthodontic therapy and forensic age estimation. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638471 Sun, 29 Jan 2012 16:46:11 +0100 5638471 http://www.medworm.com/index.php?rid=5638470&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002470%2Fabstract%3Frss%3Dyes Abstract: As a mineralised connective tissue, dentine is well adapted to its functional role as a major structural component of the tooth. Although similar in composition to bone, dentine matrix is not remodelled physiologically and traditionally, has been regarded as a rather inert tissue. Nevertheless, dentine–pulp demonstrates strong regenerative potential which allows it to respond to disease and traumatic injury. Such responses are strongly influenced by cell–matrix interactions and modified by disease processes, including infection and inflammation. The identification of many bioactive molecules bound within dentine matrix has allowed their potential involvement in regenerative and other tissue responses to be better understood and new opportunities to be recognised for novel cli... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638470 Sun, 29 Jan 2012 16:46:11 +0100 5638470 http://www.medworm.com/index.php?rid=5638469&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996912000180%2Fabstract%3Frss%3Dyes (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5638469 Sun, 29 Jan 2012 16:46:11 +0100 5638469 http://www.medworm.com/index.php?rid=5524688&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002597%2Fabstract%3Frss%3Dyes Conclusions: The results indicate that bone marrow-derived cells are preferentially recruited to wounded oral mucosa but not to wounded skin. This might be related to the larger healing potential of oral mucosa. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524688 Thu, 22 Dec 2011 05:14:43 +0100 5524688 http://www.medworm.com/index.php?rid=5524687&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002299%2Fabstract%3Frss%3Dyes Conclusions: The results of this study are consistent with and support the clinically normal features of oral mucosa in BMS, and suggest that keratin 16 may be involved in the cell mechanisms underlying the syndrome occurrence. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524687 Thu, 22 Dec 2011 05:14:43 +0100 5524687 http://www.medworm.com/index.php?rid=5524686&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002548%2Fabstract%3Frss%3Dyes Conclusions: Our results indicate that β-galactosidase is located on the cell surface of oral bacteria derived from dental plaque and tongue coating, and it plays an important role in producing the malodour underlying physiological oral malodour. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524686 Thu, 22 Dec 2011 05:14:43 +0100 5524686 http://www.medworm.com/index.php?rid=5524685&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002500%2Fabstract%3Frss%3Dyes Abstract: Mouth coating, defined as the residual food that sticks to the oral surface after food ingestion, plays an important role in both the delivery of food components and mouth feel and after-feel perceptions. The aim of this work was to adapt a rapid and simple instrumental method to the quantification of food remaining after the in vivo ingestion of a solid food. This method was investigated in 12 non-trained subjects who consumed four melted cheeses differing in terms of their fat and water contents. Mouth coating was determined by fluorescence measurements using curcumin, an oil-soluble dye that had been added to the cheeses during their preparation. The results obtained showed that this method was reproducible, reliable and discriminating and could be used for solid cheeses cover... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524685 Thu, 22 Dec 2011 05:14:43 +0100 5524685 http://www.medworm.com/index.php?rid=5524684&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100255X%2Fabstract%3Frss%3Dyes Conclusion: These results demonstrate that HMGB1 and RAGE are abundantly expressed in gingiva and promptly released during gingival inflammation. We suggest a role for HMGB1/RAGE/iNOS signalling on inflamed gingival epithelial cells. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524684 Thu, 22 Dec 2011 05:14:43 +0100 5524684 http://www.medworm.com/index.php?rid=5524683&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002536%2Fabstract%3Frss%3Dyes Abstract: Objectives: The present study aims at comparing the effects of physical and variable chronic stress on ligature-induced periodontitis in rats.Design: Forty-eight adult Wistar rats were randomly assigned to four groups (n=12): physical stress, variable stress, positive control and negative control. The models of physical stress were immobilization and immobilization associated with exposure to cold. The models of variable stress were exposure to intermittent light, 24h isolation, oral cavity examination, crowded environment, smell of blood and noise. After 10 days of physical or variable stress animals underwent experimental induction of periodontal disease in one oral side. Positive control also underwent experimental induction of periodontal disease on the 10th day. Negative con... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524683 Thu, 22 Dec 2011 05:14:43 +0100 5524683 http://www.medworm.com/index.php?rid=5524682&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002512%2Fabstract%3Frss%3Dyes Abstract: Objective: The goal of the present study was to evaluate the histopathologic and morphometric effects of systemic boric acid in a rat periodontitis model.Design: Twenty-four Wistar rats were divided into three groups of eight animals each: non-ligated (NL), ligature only (LO), and ligature and treated with boric acid (BA) (3mg/kg per day for 11 days). A 4/0 silk suture was placed in a subgingival position around the mandibular first molars; after 11 days the rats were sacrificed, and changes in alveolar bone levels were measured clinically and tissues were histopathologically examined to assess the differences amongst the study groups.Results: The ratio of presence of inflammatory cell infiltration (ICI) and osteoclast number in the LO group was significantly higher than that of ... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524682 Thu, 22 Dec 2011 05:14:43 +0100 5524682 http://www.medworm.com/index.php?rid=5524681&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002494%2Fabstract%3Frss%3Dyes Conclusion: These data suggest that PERIOSTIN upregulates MMP-2 expression via the αvβ3 integrin/ERK signalling pathway and VEGF expression in human PDL cells. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524681 Thu, 22 Dec 2011 05:14:43 +0100 5524681 http://www.medworm.com/index.php?rid=5524680&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002524%2Fabstract%3Frss%3Dyes Conclusion: R-cadherin may be a key molecule for providing control over the multipotency of the dental pulp-derived mesenchymal stem cells. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524680 Thu, 22 Dec 2011 05:14:43 +0100 5524680 http://www.medworm.com/index.php?rid=5524679&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002287%2Fabstract%3Frss%3Dyes Conclusions: Our findings suggest that IL-12 inhibits not only mechanical tooth movement, but also root resorption during orthodontic tooth movement. These findings may arise through apoptosis induced by IL-12. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524679 Thu, 22 Dec 2011 05:14:43 +0100 5524679 http://www.medworm.com/index.php?rid=5524678&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002603%2Fabstract%3Frss%3Dyes Conclusions: The results suggest that irrigation using a DWJ would be an effective means of plaque control. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524678 Thu, 22 Dec 2011 05:14:43 +0100 5524678 http://www.medworm.com/index.php?rid=5524677&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002275%2Fabstract%3Frss%3Dyes Abstract: Objectives: Oral epidemiologic investigations in China western territory have showed that the immigrants in the plateau have a higher morbidity with periodontitis. To find the possible relationship between the pathogenesis of periodontitis and altitude hypoxia, we designed a periodontitis rat model via housed in low pressure oxygen chamber and investigated the bacterial diversity in the gingival crevicular fluid (GCF).Design: Eighty Sprague-Dawley rats were divided into CON-normal, CON-hypoxia, EXP-normal and EXP-hypoxia group, without or with periodontal induce, breeding in normal environment or altitude hypoxia environment. Periodontal parameters (including gingival index, GI, and tooth mobility, TM) were measured after 2, 4, 6 and 8 weeks; periodontal samples were collected fo... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524677 Thu, 22 Dec 2011 05:14:43 +0100 5524677 http://www.medworm.com/index.php?rid=5524676&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100210X%2Fabstract%3Frss%3Dyes Abstract: Introduction: Nanoemulsions (NE) are a unique class of disinfectants produced by mixing a water immiscible liquid phase into an aqueous phase under high shear forces. NE have antimicrobial properties and are also effective anti-biofilm agents.Materials and methods: The effectiveness of nanoemulsion and its components was determined against Streptococcus mutans and Lactobacillus casei by live/dead staining. In vitro antimicrobial effectiveness of nanoemulsion against planktonic S. mutans, L. casei, Actinomyces viscosus, Candida albicans and mixed culture was determined by a serial dilution technique to obtain minimum inhibitory concentration and minimum bactericidal concentration (MIC/MBC). In addition, efficacy was investigated by kinetics of killing, adherence and biofilm assays... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524676 Thu, 22 Dec 2011 05:14:43 +0100 5524676 http://www.medworm.com/index.php?rid=5524675&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002007%2Fabstract%3Frss%3Dyes Abstract: Objective: The aim of this study was to compare the membrane fatty acid profile and expression of the fabM gene in a fluoride-resistant Streptococcus mutans strain with those of its wild-type counterpart. Additionally, we aimed to investigate whether mutations were present in the fabM gene of the fluoride-resistant strain.Design: A fluoride-resistant strain of S. mutans was obtained by step-by-step induction in vitro. The fluoride-resistant strain and its wild-type counterpart were grown anaerobically in a brain heart infusion broth, harvested and resuspended in a salt solution for an acid survival assay and a pH-drop experiment. The membrane fatty acid profile was determined by gas chromatography–mass spectrometry. Expression of the fabM gene was quantified by real-time PCR. T... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524675 Thu, 22 Dec 2011 05:14:43 +0100 5524675 http://www.medworm.com/index.php?rid=5524674&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002020%2Fabstract%3Frss%3Dyes Abstract: Saliva is an important body fluid containing a complex mixture of proteins, peptides and other substances. These are not only important in maintaining the health of the oral cavity but also may yield information about oral and systemic disease. Comprehensive analysis and identification of the proteomic content of human saliva may contribute to the understanding of oral pathophysiology and provide a foundation for the recognition of potential biomarkers of human disease. The collection of saliva samples is non-invasive, safe, and inexpensive. It seems likely that testing methods can be developed which can be used in general medical or dental practice. However, it is important to realize that the collection of saliva must be carefully controlled. In this paper we review the progres... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524674 Thu, 22 Dec 2011 05:14:43 +0100 5524674 http://www.medworm.com/index.php?rid=5524673&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911004110%2Fabstract%3Frss%3Dyes (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5524673 Thu, 22 Dec 2011 05:14:43 +0100 5524673 http://www.medworm.com/index.php?rid=5441075&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100197X%2Fabstract%3Frss%3Dyes Abstract: Objective: To investigate if Drynariae rhizoma (DR) and its main ingredient Naringin could reduce alveolar bone loss by stimulating the proliferation and differentiation of osteoblasts.Materials and methods: The effect of DR water (DRWE), ethanolic extract (DREE), and Naringin on MC3T3-E1 cells was evaluated respectively by MTT method and by measuring the activity of alkaline phosphatase (ALP activity) as well as the level of osteocalcin in medium. Bone mineral density (BMD) detection, osteoclast counting by tartrate resistant acid phosphatase staining, and histopathological analysis were performed in an induced rat model of alveolar bone resorption after gastric perfusion with DR extracts or Naringin.Results: DRWE and Naringin effectively increased the proliferation of MC3T3-E1 ... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441075 Fri, 25 Nov 2011 05:12:58 +0100 5441075 http://www.medworm.com/index.php?rid=5441074&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001932%2Fabstract%3Frss%3Dyes Conclusions: Very short term nasal obstruction, i.e. forced oral breathing, leads to long term hormonal changes and respiratory muscle fibre adaptation. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441074 Fri, 25 Nov 2011 05:12:58 +0100 5441074 http://www.medworm.com/index.php?rid=5441073&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002482%2Fabstract%3Frss%3Dyes Abstract: Objective: The purpose of the present study was to examine the age- and tissue-related variations of the telomere length in gingiva and dental pulp of donor patients.Design: We quantified the relative telomeric DNA content corresponding to the telomere length in gingiva or dental pulp from donor patients (male and female, aged at 19–68) by using genomic DNA of oral tissues in dot-blot hybridization with telomere-specific probe.Results: Telomeric DNA content in the dental pulp showed a negative correlation with the age of donor patients, with smaller telomeric DNA content observed in the elders (p (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441073 Fri, 25 Nov 2011 05:12:58 +0100 5441073 http://www.medworm.com/index.php?rid=5441072&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001968%2Fabstract%3Frss%3Dyes Abstract: Objective: The aim of the present study was to evaluate and compare the expression of CD105 (endoglin) in solid multicystic ameloblastoma (SMA) and unicystic ameloblastoma (UA).Materials and methods: Angiogenesis was assessed in 20 SMA, 15 UA and 10 normal oral mucosa samples by measuring the mean vascular density (MVD), total vascular area (TVA) and mean vascular area (MVA). The immunohistochemistry was carried out by using monoclonal mouse anti-human antibody against CD105.Results: The Kruskal–Wallis test showed significant difference in mean MVD, TVA, and MVA between SMA, UA, and control group (p (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441072 Fri, 25 Nov 2011 05:12:58 +0100 5441072 http://www.medworm.com/index.php?rid=5441071&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001944%2Fabstract%3Frss%3Dyes Conclusions: Our observations suggest a dual embryonic origin of the incisors in minipigs with the first and second incisors originating from the frontonasal prominence whilst the third incisor forms from tissues derived from the maxillary prominence. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441071 Fri, 25 Nov 2011 05:12:58 +0100 5441071 http://www.medworm.com/index.php?rid=5441070&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002263%2Fabstract%3Frss%3Dyes Conclusion: The maximum OCA during chewing is nearly identical to statically determined maximum possible OCA. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441070 Fri, 25 Nov 2011 05:12:58 +0100 5441070 http://www.medworm.com/index.php?rid=5441069&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002044%2Fabstract%3Frss%3Dyes In this study, to elucidate the effects of preferred properties of food that affect the daily masticatory habits on the onset of lifestyle-related disease, we investigated whether groups of rats continuously fed with diet having distinct properties show differences in glucose metabolism.Design: Thirty-six male Wistar rats aged 4 weeks were divided into two groups; only the pellet type feed was given to one (solid diet group), and the powdered feed to the other (powder diet group).The oral glucose tolerance test (OGTT) was performed to measure glucose metabolism.For the determination of statistical significance (p (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441069 Fri, 25 Nov 2011 05:12:58 +0100 5441069 http://www.medworm.com/index.php?rid=5441068&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002032%2Fabstract%3Frss%3Dyes Conclusions: Our results provide the first evidence of increased expression of a cold-sensitive TRP channel in trigeminal ganglia after pulp exposure, and are consistent with the possibility that increased expression and function of TRPA1 in trigeminal neurons contributes to hyperalgesia and allodynia following tooth injury. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441068 Fri, 25 Nov 2011 05:12:58 +0100 5441068 http://www.medworm.com/index.php?rid=5441067&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001701%2Fabstract%3Frss%3Dyes Conclusions: The results demonstrate poor oral health amongst 18th century population of continental Croatia, exhibiting high antemortem teeth loss, high periodontal disease frequency and occlusal and proximal caries frequency. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441067 Fri, 25 Nov 2011 05:12:58 +0100 5441067 http://www.medworm.com/index.php?rid=5441066&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100207X%2Fabstract%3Frss%3Dyes Conclusions: These results demonstrated the synergistic effects of TLR ligands and P. gingvalis cysteine proteases for the proinflammatory responses in artery vascular endothelial cells and highlight a mechanism by which bacteria may contribute to the development of atherosclerosis. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441066 Fri, 25 Nov 2011 05:12:58 +0100 5441066 http://www.medworm.com/index.php?rid=5441065&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100135X%2Fabstract%3Frss%3Dyes Conclusion: The antimicrobial effectiveness of the tested thiocyanate hydrogen peroxide combination was increased significantly by adding lactoperoxidase in the quantitative suspension test under human saliva loading. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441065 Fri, 25 Nov 2011 05:12:58 +0100 5441065 http://www.medworm.com/index.php?rid=5441064&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002081%2Fabstract%3Frss%3Dyes Abstract: Objective: (i) To compare individuals with self-reported bruxism and non-bruxist individuals in terms of maximal bite force (MBF) and temporomandibular joint (TMJ) primary assessment parameters and (ii) to examine the relationship between MBF and tooth wear in these subjects.Materials and methods: Twenty-nine bruxist subjects and 29 healthy controls were enrolled. MBF measurements were carried out by the use of bite force recorder. Tooth wear indices, maximal mouth opening, maximal lateral excursions and maximal protrusions were measured for every subject.Results: MBF and tooth wear index scores were significantly higher in bruxists (p values (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441064 Fri, 25 Nov 2011 05:12:58 +0100 5441064 http://www.medworm.com/index.php?rid=5441063&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002068%2Fabstract%3Frss%3Dyes Conclusions: Increased urease activity in saliva can be an indicator of increased caries risk in children, whilst increased urease activity in plaque may be associated with reduced caries risk. The reproducibility of urease measurements must be improved before these findings can be further tested and clinically applied. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441063 Fri, 25 Nov 2011 05:12:58 +0100 5441063 http://www.medworm.com/index.php?rid=5441062&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002056%2Fabstract%3Frss%3Dyes Abstract: In the following respects, tooth enamel is a unique tissue in the mammalian body: (a) it is the most mineralized and hardest tissue in it comprising up to 95wt% of apatite; (b) its microstructure is dominated by parallel rods composed of bundles of 40–60nm wide apatite crystals with aspect ratios reaching up to 1:10,000 and (c) not only does the protein matrix that gives rise to enamel guides the crystal growth, but it also conducts its own degradation and removal in parallel. Hence, when mimicking the process of amelogenesis in vitro, crystal growth has to be coupled to proteolytic digestion of the amelogenin assemblies that are known to play a pivotal role in conducting the proper crystal growth. Experimental settings based on controlled and programmable titration of amelogen... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441062 Fri, 25 Nov 2011 05:12:58 +0100 5441062 http://www.medworm.com/index.php?rid=5441061&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001993%2Fabstract%3Frss%3Dyes Conclusion: The highest anti-erosive potential was found after combined cerium chloride and amine fluoride application. Laser irradiation had not adjunctive effect. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441061 Fri, 25 Nov 2011 05:12:58 +0100 5441061 http://www.medworm.com/index.php?rid=5441060&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001713%2Fabstract%3Frss%3Dyes Conclusion: The optimal delivery of rhsTNF-RI was local injection of 0.1ml at 0.1μg/ml every three days. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441060 Fri, 25 Nov 2011 05:12:58 +0100 5441060 http://www.medworm.com/index.php?rid=5441059&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001981%2Fabstract%3Frss%3Dyes Conclusions: Individuals with orofacial dysfunction presented impairment in ORHQoL, but not enough to change salivary cortisol levels. Furthermore, gender did not have influence on ORHQoL in the studied sample. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441059 Fri, 25 Nov 2011 05:12:58 +0100 5441059 http://www.medworm.com/index.php?rid=5441058&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001956%2Fabstract%3Frss%3Dyes Conclusions: Parotid glands from rats with experimental periodontitis release more amylase in response to carbachol suggesting an interaction between Ca2+ and cAMP in the fusion/exocytosis step of secretory vesicles. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441058 Fri, 25 Nov 2011 05:12:58 +0100 5441058 http://www.medworm.com/index.php?rid=5441057&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001695%2Fabstract%3Frss%3Dyes Conclusion: High quality miRNAs can be isolated from saliva using available commercial kits, and in future studies, the availability of this isolation protocol may allow specific changes in their levels to be measured accurately in various relevant diseases. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441057 Fri, 25 Nov 2011 05:12:58 +0100 5441057 http://www.medworm.com/index.php?rid=5441056&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002111%2Fabstract%3Frss%3Dyes This study aims to evaluate whether the genetic risk score may predict periodontitis onset and progression.Materials and methods: Fifty patients were divided into various groups according to periodontal status. Total DNA was isolated from epithelial oral cells by a masked operator and the selected SNPs were analysed. A GRS was calculated using an additive model.Results: We found a strong association only between TNF rs1800629 and diffused forms of periodontitis. Data show that GRS is able to discriminate diffused forms of periodontitis from localized ones. Finally, a progressive increase of the GRS is evident in advanced periodontitis in comparison with early forms.Discussion: In recent years, research on genetic polymorphism has had limited success in predicting the susceptibility to peri... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441056 Fri, 25 Nov 2011 05:12:58 +0100 5441056 http://www.medworm.com/index.php?rid=5441055&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002019%2Fabstract%3Frss%3Dyes Conclusions: These data indicated that VDR TaqI polymorphism is differentially associated with development of chronic periodontitis and aggressive periodontitis in Italian population. The study of VDR polymorphisms may therefore be essential for the prevention of periodontitis and for a pre-treatment periodontal and/or for implant assessment. Moreover VDR TaqI polymorphism could be useful to discriminate between aggressive and chronic forms of periodontal disease. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441055 Fri, 25 Nov 2011 05:12:58 +0100 5441055 http://www.medworm.com/index.php?rid=5441054&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001920%2Fabstract%3Frss%3Dyes Conclusions: The Q551R IL-4RA polymorphism is a putative risk indicator for severe chronic periodontitis, but was not significant associated to AP. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441054 Fri, 25 Nov 2011 05:12:58 +0100 5441054 http://www.medworm.com/index.php?rid=5441053&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002093%2Fabstract%3Frss%3Dyes Conclusions: The PDGF plays a significant role in periodontal bone and tissue regeneration. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441053 Fri, 25 Nov 2011 05:12:58 +0100 5441053 http://www.medworm.com/index.php?rid=5441052&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001555%2Fabstract%3Frss%3Dyes Abstract: Intraoral bone grafting is routinely employed for implant site development prior or simultaneously to implant placement. Bone graft consolidation is a complex biological process depending on the formation of blood vessels into the augmented area. It is highly regulated by the angiogenesis and osteogenesis coupling phenomenon. The vascular system apart from supplying nutrients and oxygen to the developing and regenerating bone, also delivers critical signals which stimulate mesenchymal cell differentiation towards an osteogenic phenotype.Hypoxia inducible factors (HIFs) and mimicking agents (HMAs) (or alternatively HIF stabilizing agents) are considered to act as key stimulators of blood vessel formation. Under normoxia, HIFs are rapidly degraded. However, their degradation is pre... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441052 Fri, 25 Nov 2011 05:12:58 +0100 5441052 http://www.medworm.com/index.php?rid=5441051&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001245%2Fabstract%3Frss%3Dyes Abstract: This review describes evidence in subprimates and primates that the face primary somatosensory cortex (face SI) and primary motor cortex (face MI) are involved in sensorimotor integration and control of orofacial motor functions that include semiautomatic movements (e.g., chewing, swallowing) and voluntary movements (e.g., jaw-opening). The review also notes that the neuroplastic capabilities of the face SI and face MI have recently been documented, and may reflect or allow for functional adaptation (or maladaptation) of the orofacial sensorimotor system to an altered oral state or oral motor behaviour. They may contribute to the processes whereby patients undergoing oral rehabilitation can (or cannot) restore the lost orofacial sensorimotor functions. Such understanding is impor... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441051 Fri, 25 Nov 2011 05:12:58 +0100 5441051 http://www.medworm.com/index.php?rid=5441050&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002123%2Fabstract%3Frss%3Dyes Although it is difficult to translate findings on maladaptative cortical plasticity from animal to humans, it is generally accepted that cortical sensory maps can be modified by deafferentation or injury and such plasticity has been accounted to interactions between ‘bottom-up’ and ‘top-down’ mechanisms. In this issue of the Archives of Oral Biology, Avivi-Arber et al. develop several exciting working hypotheses that may help in the near future, to build a unifying theory about sensorimotor cortex plasticity and maladaptative changes, which lead to impaired orofacial functions and thus dramatically affect the quality of life. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441050 Fri, 25 Nov 2011 05:12:58 +0100 5441050 http://www.medworm.com/index.php?rid=5441049&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911003694%2Fabstract%3Frss%3Dyes (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5441049 Fri, 25 Nov 2011 05:12:58 +0100 5441049 http://www.medworm.com/index.php?rid=5347561&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001221%2Fabstract%3Frss%3Dyes Conclusions: These findings indicate that both caries and tooth wear may be related to the subsistence and diet of this Neolithic population. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347561 Wed, 26 Oct 2011 10:55:45 +0100 5347561 http://www.medworm.com/index.php?rid=5347560&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001361%2Fabstract%3Frss%3Dyes This study tested the possible influence of the natural ability to roll the tongue and modulations of tongue-training parameters on tongue-training performance.Design: A total of 44 healthy adult subjects participated. 29 subjects (15 with and 14 without ability to roll their tongue) performed 1h standard tongue-training task. Another 15 subjects participated in 2 sessions: Standard and Modulation in randomized order. Standard session: 1h tongue-training with fixed training parameters; Modulation session: 1h tongue-training with modulation of training parameters every 20min (3 different settings – A, B, C, with different timing of task). Perceived task difficulty was evaluated on a 0–10 numerical rating scale (NRS).Results: All participants improved performance during training (P (Sour... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347560 Wed, 26 Oct 2011 10:55:45 +0100 5347560 http://www.medworm.com/index.php?rid=5347559&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001592%2Fabstract%3Frss%3Dyes Abstract: Extracellular matrix degradation in mandibular condylar cartilage is mediated by various cytokines in the temporomandibular joint (TMJ). Interleukin-1 beta (IL-1β) is detected in joint structures with pathologic status, and participates in catabolic action in the extracellular matrix. The purpose of this study was to investigate the effects of IL-1β on cyclooxygenase-2 (COX-2) expression and cartilage metabolism using cultured chondrocytes from mandibular condyle. Articular chondrocytes from the porcine mandibular condylar cartilage around the surface were cultured and treated with 0–10ng/ml IL-1β or 0–1000ng/ml prostaglandin (PGE2) for 0–24h. The mRNA levels of COX-2, MMP-1, -3, and -13 were evaluated by real-time PCR analysis. The protein levels of PGE2 and MMPs were e... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347559 Wed, 26 Oct 2011 10:55:45 +0100 5347559 http://www.medworm.com/index.php?rid=5347558&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001580%2Fabstract%3Frss%3Dyes Conclusions: These results suggest that sympathetic nervous activity may influence the alveolar bone loss induced by occlusal hypofunction. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347558 Wed, 26 Oct 2011 10:55:45 +0100 5347558 http://www.medworm.com/index.php?rid=5347557&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001373%2Fabstract%3Frss%3Dyes Conclusion: Inhaled budesonide in different concentrations did not alter alveolar bone loss and TNF-α secretion in male Wistar rats. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347557 Wed, 26 Oct 2011 10:55:45 +0100 5347557 http://www.medworm.com/index.php?rid=5347556&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001269%2Fabstract%3Frss%3Dyes Conclusion: The results of this study demonstrated that the thickness of the tidemark was related to load-bearing on the articular surface. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347556 Wed, 26 Oct 2011 10:55:45 +0100 5347556 http://www.medworm.com/index.php?rid=5347555&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100121X%2Fabstract%3Frss%3Dyes Conclusion: These MRI findings closely agreed with those observed with haematoxylin–eosin staining under light microscopy, suggesting that MRI is a useful method for analyzing the complex structure of the TMJ in the rat. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347555 Wed, 26 Oct 2011 10:55:45 +0100 5347555 http://www.medworm.com/index.php?rid=5347554&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001208%2Fabstract%3Frss%3Dyes Conclusions: Bone loss increased strain mainly in the buccal region. Dental splints with adhesive system and composite resin produced lower bone strains irrespective of occlusal load. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347554 Wed, 26 Oct 2011 10:55:45 +0100 5347554 http://www.medworm.com/index.php?rid=5347553&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001312%2Fabstract%3Frss%3Dyes Conclusions: These results provide clinical data indicating that VEGF expression may be a useful predictive marker for the effects of PDT in OSCC and OED. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347553 Wed, 26 Oct 2011 10:55:45 +0100 5347553 http://www.medworm.com/index.php?rid=5347552&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001725%2Fabstract%3Frss%3Dyes Conclusions: We succeeded in expressing Stim1-mKO1 fluorescent protein in the salivary glands of live animals by retrograde ductal injection of an adenoviral vector. This method allowed us to investigate the functions and molecular dynamics of these expressed molecules in living salivary acinar cells. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347552 Wed, 26 Oct 2011 10:55:45 +0100 5347552 http://www.medworm.com/index.php?rid=5347551&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001683%2Fabstract%3Frss%3Dyes Conclusion: These data together suggest that high potassium in saliva bathing the mouse submandibular granular convoluted tubular cells has a potent feedback effect on ACh and NA stimulation, and sodium/calcium exchange is likely to play a major role in this process. Such positive feedback actions of high potassium may suggest a role for enhancing ACh- or NA-stimulated protein factor secretion from the granulated convoluted tubular cells. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347551 Wed, 26 Oct 2011 10:55:45 +0100 5347551 http://www.medworm.com/index.php?rid=5347550&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001609%2Fabstract%3Frss%3Dyes Conclusions: In a rat model the administration of natural antioxidants could be of beneficial effect on prevention of cytotoxicity induced by organophosphorous compounds. However, green tea showed more promising results than that of Nigella sativa. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347550 Wed, 26 Oct 2011 10:55:45 +0100 5347550 http://www.medworm.com/index.php?rid=5347549&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001385%2Fabstract%3Frss%3Dyes Conclusions: The high-level expression and subcellular distribution pattern of sialin in the SMG suggest that sialin may play an important role in the transport and secretion of saliva. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347549 Wed, 26 Oct 2011 10:55:45 +0100 5347549 http://www.medworm.com/index.php?rid=5347548&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001324%2Fabstract%3Frss%3Dyes Conclusion: The salivary characteristics are similar amongst 12–13-year-old schoolchildren with and without dental erosion in Southern China. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347548 Wed, 26 Oct 2011 10:55:45 +0100 5347548 http://www.medworm.com/index.php?rid=5347547&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001646%2Fabstract%3Frss%3Dyes Conclusions: These findings suggest that bPN has therapeutic effects on bone-destructive processes, such as those that occur in periodontal diseases. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347547 Wed, 26 Oct 2011 10:55:45 +0100 5347547 http://www.medworm.com/index.php?rid=5347546&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001294%2Fabstract%3Frss%3Dyes Conclusion: These results suggest that CRP induced locally by periodontal infection may play another role in the pathogenesis of periodontal disease, and to a much lesser extent, has the potential to modulate systemic CRP level by extra-hepatic CRP production. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347546 Wed, 26 Oct 2011 10:55:45 +0100 5347546 http://www.medworm.com/index.php?rid=5347545&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001737%2Fabstract%3Frss%3Dyes Abstract: Objectives: The present study is to assess Streptococcus mutans survivability in different starvation conditions and to determine the resistance of starved S. mutans to lethal acid and two common anti-caries agents, sodium fluoride (NaF) and chlorhexidine acetate (CHX).Methods: S. mutans survival rates in sterile water, PBS, sterile saliva, 1/5 strength BHI and BHI were determined at a given time by plate count of viable cell. The resistance of starved S. mutans and control S. mutans to four times the minimal bactericidal concentration (MBC) of NaF, two times the MBC of CHX and acid (pH 2.8) was evaluated and compared respectively. Furthermore, field emission scanning electron microscope (FE-SEM) was used to observe the morphologic characteristics of the starved S. mutans cells.R... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347545 Wed, 26 Oct 2011 10:55:45 +0100 5347545 http://www.medworm.com/index.php?rid=5347544&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001671%2Fabstract%3Frss%3Dyes Abstract: The effect of erythrosine- and LED-mediated photodynamic therapy (PDT) on planktonic cultures and biofilms of Candida albicans and Candida dubliniensis was evaluated. Planktonic cultures of standardized suspensions (106cells/mL) of C. albicans and C. dubliniensis were treated with erythrosine concentrations of 0.39–200μM and LEDs in a 96-well microtiter plate. Biofilms formed by C. albicans and C. dubliniensis in the bottom of a 96-well microtiter plate were treated with 400μM erythrosine and LEDs. After PDT, the biofilms were analysed by scanning electron microscopy (SEM). The antimicrobial effect of PDT against planktonic cultures and biofilms was verified by counting colony-forming units (CFU/mL), and the data were submitted to analysis of variance and the Tukey test (P (S... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347544 Wed, 26 Oct 2011 10:55:45 +0100 5347544 http://www.medworm.com/index.php?rid=5347543&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100166X%2Fabstract%3Frss%3Dyes Conclusion: We have demonstrated that an experimental bacteremia of P. gingivalis could induce myocarditis and/or myocardial infarction in mice, and IL-17A plays an important role in the pathogenesis of these diseases. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347543 Wed, 26 Oct 2011 10:55:45 +0100 5347543 http://www.medworm.com/index.php?rid=5347542&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001348%2Fabstract%3Frss%3Dyes The objective of this study was to evaluate the distribution and pattern of urease activity in the dental plaque and in the saliva of children during a three-year period, and to examine the relationship of urease with some important caries risk factors.Methods: A longitudinal study was conducted with repeated measures over a three-year period on a panel of 80 children, aged 3–6 years at recruitment. The dynamics of change in urease activity were described and associated with clinical, biological, and behavioural caries risk factors.Results: Urease activity in plaque showed a trend to remain stable during the study period and was negatively associated with sugar consumption (P (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347542 Wed, 26 Oct 2011 10:55:45 +0100 5347542 http://www.medworm.com/index.php?rid=5347541&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001257%2Fabstract%3Frss%3Dyes Abstract: Objective: The aim of this study was to evaluate whether fluconazole (FLZ) could affect the bioactivity and cellular structure of Candida albicans or Candida glabrata biofilms grown in the presence of FLZ.Materials and methods: Tokens were fabricated using poly(methylmethacrylate) resin (PMMA) in a hot water bath. Salivary pellicles were formed on the PMMA surface, and biofilms of a reference strain and two clinical isolates of C. albicans (ATCC 90028, P01 and P34) and C. glabrata (ATCC 2001, P11 and P31) were developed for a period of 48h. Control and experimental groups were formed. FLZ at the bioavailable concentration in saliva (2.56μg/mL) was added to the medium of the experimental group. The culture mediums of the control and experimental groups were changed after 24h. The... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347541 Wed, 26 Oct 2011 10:55:45 +0100 5347541 http://www.medworm.com/index.php?rid=5347540&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001233%2Fabstract%3Frss%3Dyes Conclusion: The largest compositional changes occurred in nascent plaques where the addition of lactobacilli caused significant increases in streptococci and Gram-negative anaerobes, the latter possibly via lactate syntrophy. Exogenous L. reuteri persisted in mature plaque microcosms after dosing ceased. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347540 Wed, 26 Oct 2011 10:55:45 +0100 5347540 http://www.medworm.com/index.php?rid=5347539&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001634%2Fabstract%3Frss%3Dyes Conclusion: Ours findings indicate the presence of RANK, RANKL and OPG in cysts. Moreover, increased expression of OPG compared to RANKL in the lining epithelium could contribute to the differential bone resorption activity in theses lesions. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347539 Wed, 26 Oct 2011 10:55:45 +0100 5347539 http://www.medworm.com/index.php?rid=5347538&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001622%2Fabstract%3Frss%3Dyes Conclusions: Our results reinforce that the dental pulp is an important source of adult stem cells and encourage studies on therapeutic potential of mDPSC in experimental disease models. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347538 Wed, 26 Oct 2011 10:55:45 +0100 5347538 http://www.medworm.com/index.php?rid=5347537&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001610%2Fabstract%3Frss%3Dyes Conclusions: Gene expression was differentially regulated according to the type of mechanical stimulation applied to cementoblasts. In addition, it is shown that PGE2 plays an important role on mediating cementoblast mechanosensitivity. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347537 Wed, 26 Oct 2011 10:55:45 +0100 5347537 http://www.medworm.com/index.php?rid=5347536&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001579%2Fabstract%3Frss%3Dyes Conclusions: These results indicate that pressure could induce IL-6 expression through the P2Y6 receptor in HDPCs, leading to a new insight of the role of pressure on cytokine release during pulpal inflammatory process. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347536 Wed, 26 Oct 2011 10:55:45 +0100 5347536 http://www.medworm.com/index.php?rid=5347535&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001567%2Fabstract%3Frss%3Dyes Conclusion: It was concluded that TGF-β1 combining with transfilter could induce odontoblast differentiation and dentin formation. Our results implied that suitable substrate for the progenitors of odontoblast to anchor on and inductive signals to initiate the differentiation of odontoblast should be taken into consideration when designing scaffold material for inducing dentin tissue engineering. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347535 Wed, 26 Oct 2011 10:55:45 +0100 5347535 http://www.medworm.com/index.php?rid=5347534&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001336%2Fabstract%3Frss%3Dyes Conclusions: All nine voltage-gated sodium channels could be expressed by odontoblasts, depending on intradental location and tooth maturity. Our data reveal much greater complexity and niche-specific specialization for odontoblasts than previously demonstrated, with implications for tooth sensitivity. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347534 Wed, 26 Oct 2011 10:55:45 +0100 5347534 http://www.medworm.com/index.php?rid=5347533&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001300%2Fabstract%3Frss%3Dyes Abstract: Objective: To evaluate the effect of ferrous sulphate on enamel demineralization and remineralization, using pH-cycling models.Design: Fifty blocks were selected by their initial surface hardness and subjected to a pH-cycling demineralization process. Artificially demineralized lesions were produced in 60 blocks; out of these blocks, the surface hardness of 50 blocks and the cross-sectional hardness of 10 blocks were determined. The 50 blocks were then subjected to a remineralization pH-cycling process. Treatments were carried out using ferrous sulphate solutions of different concentrations (0.333, 0.840, 18.0, and 70.0μg Fe/mL) and a control group (deionized water). The final surface hardness (SH2) was determined, and the integrated subsurface hardness (ΔKHN) was calculated. T... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347533 Wed, 26 Oct 2011 10:55:45 +0100 5347533 http://www.medworm.com/index.php?rid=5347532&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000926%2Fabstract%3Frss%3Dyes Abstract: The field of temporomandibular disorders (TMD) is experiencing significant changes in terms of aetiology and treatment. Researchers and clinicians are becoming increasingly aware of the possibility that genetic variations may play a role in pain perception and onset of TMD. In this review, we purpose to briefly describe these allelic variants, how they may be involved in TMD pathophysiology and how they may affect TMD treatment. Studies have already pointed the association between TMD and genetic polymorphisms in the oestrogen receptor alpha, adrenergic receptor beta 2, serotonin receptor, serotonin transporter and catechol-O-methyltransferase genes, and other candidate genes continue to emerge. The main implication of these findings refers to the promising possibilities of “ge... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347532 Wed, 26 Oct 2011 10:55:45 +0100 5347532 http://www.medworm.com/index.php?rid=5347531&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001658%2Fabstract%3Frss%3Dyes With increasing life expectancy in developed countries, the number of elderly patients is increasing too. This means there is a growing number of patients with complex dentitions and a history of periodontal treatment, prosthodontics, implants and aesthetic surgery. Concomitantly, immune competency decreases with age. This combination, together with an increase in the incidence of (oral) cancer, makes the ageing population more vulnerable to opportunistic infections like (oral) candidiasis, and also to periodontal infection. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347531 Wed, 26 Oct 2011 10:55:45 +0100 5347531 http://www.medworm.com/index.php?rid=5347530&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911003177%2Fabstract%3Frss%3Dyes (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5347530 Wed, 26 Oct 2011 10:55:45 +0100 5347530 http://www.medworm.com/index.php?rid=5285712&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001282%2Fabstract%3Frss%3Dyes Conclusions: These results suggested that hAE cells may be a promising cell source for the development of stratified epithelium allograft sheets using a human cell strain. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285712 Sat, 01 Oct 2011 04:00:00 +0100 5285712 http://www.medworm.com/index.php?rid=5285711&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000896%2Fabstract%3Frss%3Dyes Conclusions: BQ-chewers who carry the G allele or G/G genotype in TNFA −308 may have an increased risk of OPSCC. The intensity of cigarette smoking modulates the effect of the combined TNFA genotypes on risk of BQ-related OPSCC. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285711 Sat, 01 Oct 2011 04:00:00 +0100 5285711 http://www.medworm.com/index.php?rid=5285710&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000884%2Fabstract%3Frss%3Dyes Conclusion: CSC increased the collagen degrading ability of SCC-25 by increasing the MMP-2 and MMP-9 protein levels. Continued cigarette smoking in oral cancer patients may result in decreased survival rates due to enhanced metastatic potential of the cancer cells. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285710 Sat, 01 Oct 2011 04:00:00 +0100 5285710 http://www.medworm.com/index.php?rid=5285709&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000653%2Fabstract%3Frss%3Dyes This study included thirty patients with a clinicopathological diagnosis of oral lichen planus (all with atrophic–erosive clinical forms of OLP) and thirty healthy control subjects. Both samples were similar in age and gender. The buccal micronucleus cytome assay protocol consisted of: cell collection from both cheeks with a cytobrush; cell centrifuge; slide preparation, fixation and staining followed by fluorescent microscope analysis. 2×106 exfoliated cells were screened for nuclear abnormalities: micronuclei, nuclear buds, binucleation, basal and differentiated cells, condensed chromatin, karyorrhectic cells, pyknosis and karyolytic cells.Results: Patients with oral lichen planus showed significantly higher frequencies of micronuclei (p (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285709 Sat, 01 Oct 2011 04:00:00 +0100 5285709 http://www.medworm.com/index.php?rid=5285708&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001191%2Fabstract%3Frss%3Dyes The objective of this study was to investigate salivary flow and xerostomia in patients with orofacial pain.Design: This was a case-control study; we evaluated 82 patients with chronic orofacial pain compared with 56 healthy subjects using a Clinical Pain Questionnaire (pain characteristics, duration, intensity and descriptors), complete dental examination (including static and dynamic evaluation of the jaw) and a Xerostomia Inventory. The salivary flow was quantitatively evaluated. Data was compared through Pearson's chi-square, Fisher's exact, analysis of variance (ANOVA) 1 factor and Mann–Whitney tests.Results: Patients often had temporomandibular disorder (TMD) (P=0.001) and pain during facial (P (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285708 Sat, 01 Oct 2011 04:00:00 +0100 5285708 http://www.medworm.com/index.php?rid=5285707&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000987%2Fabstract%3Frss%3Dyes Abstract: Background: Attention deficit hyperactivity disorder (ADHD) is a childhood neurological disorder that presents in 3–7% of school-age children. Studies have shown that children, adolescents and young adults with ADHD are more prone to caries than those without.Aim: The study investigated a possible relationship between the oral health status of children, adolescents and young adults diagnosed with ADHD, both with and without pharmacological intervention, and the following: salivary flow rate, oral mucosal pH, plaque index (PI), oral hygiene and dietary behaviour.Study design: DMFT/dmft index (D;d-Decay, M;m-Missing; F;f-Filled,T;t-teeth), plaque index, oral mucosal pH and unstimulated whole salivary flow (USF) were examined in three groups of children, adolescents and young adul... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285707 Sat, 01 Oct 2011 04:00:00 +0100 5285707 http://www.medworm.com/index.php?rid=5285706&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100094X%2Fabstract%3Frss%3Dyes The objective of this study was to evaluate the effect of oestrogen replacement therapy combined with insulin treatment on the expression of oestrogen (ER-alpha) and insulin receptors (INS-R) in the salivary glands of spontaneously diabetic mice. Twenty-five mice were divided into five group of 5 animals each: group I (NOD diabetic), group II (NOD diabetic treated with insulin), group III (NOD diabetic treated with oestrogen), group IV (NOD diabetic treated with insulin and oestrogen), and group V (control BALB/c mice). Group II received insulin, group III received oestrogen, and group IV received insulin plus oestrogen administered daily for 20 days. Groups I and V received saline for the same period of time to simulate treatment. Glucose and oestrogen levels were monitored during the exp... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285706 Sat, 01 Oct 2011 04:00:00 +0100 5285706 http://www.medworm.com/index.php?rid=5285705&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001026%2Fabstract%3Frss%3Dyes Abstract: Objective: : Evaluate expression of inducible negative regulators of JAK/STAT pathway and their target proteins during the course of ligature-induced experimental periodontal disease in rats.Design: : Rats were sacrificed 07, 15 and 30days after disease induction for histological evaluation of periodontal inflammation and macroscopic analysis of alveolar bone loss. SOCS expression and the activation status of STAT1 and STAT3 were evaluated in gingival biopsies by real time PCR and Western blot.Results: : Ligature-induced model presented significant progressive bone loss from 7 to 30days. Inflammation was evident and similar for 07 and 15days; however, a decrease on severity at the end of the experimental period was observed. There was a significant (p (Source: Archives of Oral Bi... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285705 Sat, 01 Oct 2011 04:00:00 +0100 5285705 http://www.medworm.com/index.php?rid=5285704&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001014%2Fabstract%3Frss%3Dyes Abstract: Objective: Along with conventional non-surgical periodontal therapy (NSPT) systemic antimicrobials may provide more effective treatment for chronic periodontitis by targeting tissue-invasive bacteria. The aim of this randomized, placebo-controlled, double-masked clinical trial was to evaluate the adjunctive effects of oral clarithromycin (CLM) to non-surgical periodontal therapy for chronic periodontitis.Methods: 40 patients were categorized into two groups: test group – scaling and root planing (SRP) plus CLM (500mg b.i.d. for 3 days) and control group – SRP plus placebo. Clinical parameters were recorded at baseline and at 1, 3, 6, and 9 months. They included gingival index (GI), probing depth (PD), and clinical attachment level (CAL). Also microbial analysis of dental plaq... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285704 Sat, 01 Oct 2011 04:00:00 +0100 5285704 http://www.medworm.com/index.php?rid=5285703&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001002%2Fabstract%3Frss%3Dyes Conclusion: To our knowledge, this is the first study reporting that the expression of HMGB1 and HMGN2 was increased in the gingival tissues and GCF in CP and G-AgP and the PICF in PICF. Our data suggest that HMGB1 may be a potential target for the therapy of periodontitis and PI. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285703 Sat, 01 Oct 2011 04:00:00 +0100 5285703 http://www.medworm.com/index.php?rid=5285702&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000975%2Fabstract%3Frss%3Dyes Conclusion: The results demonstrated a strong colonisation of Candida spp. in the periodontal sites of diabetic patients that have generalised chronic periodontitis with a higher prevalence of C. dubliniensis followed by C. albicans. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285702 Sat, 01 Oct 2011 04:00:00 +0100 5285702 http://www.medworm.com/index.php?rid=5285701&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000963%2Fabstract%3Frss%3Dyes Conclusion: These results suggest that nicotine induces apoptosis through the ROS generation and CASP3 dependent pathways in HGFs. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285701 Sat, 01 Oct 2011 04:00:00 +0100 5285701 http://www.medworm.com/index.php?rid=5285700&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000914%2Fabstract%3Frss%3Dyes The objective of this study was to investigate the association amongst the single nucleotide polymorphisms of genes encoding for matrix metalloproteinase (MMP) 1, 3, 9 and cyclooxygenase-2 (COX-2) of subjects. Protein production of MMPs, COX-2 and Vascular Endothelial Growth Factor (VEGF) were also investigated.Methods: 280 chronic periodontitis patients and 250 periodontitis-free subjects were selected. DNA was extracted from blood samples of all patients, the polymorphic sites of the genes that encode for metalloproteinases and cyclooxygenase-2 were amplified using PCR, and digested with restriction enzymes. ELISA was used to determine the protein production of MMPs, COX-2 and VEGF.Results: The mean probing depth (PD) was 5.4mm and the clinical attachment loss (CAL) was 6.4mm in patients... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285700 Sat, 01 Oct 2011 04:00:00 +0100 5285700 http://www.medworm.com/index.php?rid=5285699&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000860%2Fabstract%3Frss%3Dyes Conclusion: Bad, Bax, cytochrome c, p53, and caspases-2, -3, -8, and -9 are pro-apoptotic proteins. Bcl-2 and Bcl-xL are anti-apoptotic proteins. Thus, the mechanism of NIF-induced gingival overgrowth might be related to decreased apoptosis in NIFr through a reduction of Bax, cytochrome c, and caspase-3 and -9. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285699 Sat, 01 Oct 2011 04:00:00 +0100 5285699 http://www.medworm.com/index.php?rid=5285698&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000689%2Fabstract%3Frss%3Dyes Conclusion: These findings indicated that TLR2, TLR4, NOD1, and NOD2 are functional receptors in HPDLFs during innate immune responses to invading bacteria, and a combination of signalling through TLRs and NODs leads to the synergistic enhancement of inflammatory reactions in HPDLFs. In addition, TLR and NOD signalling involving TRAF6 contribute to inflammatory responses in HPDLFs. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285698 Sat, 01 Oct 2011 04:00:00 +0100 5285698 http://www.medworm.com/index.php?rid=5285697&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000938%2Fabstract%3Frss%3Dyes Conclusions: A. actinomycetemcomitans residing in a dual species biofilm with the commensal, S. sanguinis can be selectively killed, or at least rendered metabolically inactive, by treatment with ciprofloxacin. The dual species biofilm model will be a useful tool for designing in vivo studies to determine the efficacy of selective killing agents as an adjunct treatment of localized aggressive forms of periodontal disease. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285697 Sat, 01 Oct 2011 04:00:00 +0100 5285697 http://www.medworm.com/index.php?rid=5285696&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000677%2Fabstract%3Frss%3Dyes Abstract: Objective: Dental caries is the main common infectious disease in the human oral cavity. Streptococcus mutans and Streptococcus sobrinus were reported to be the most important etiological factors in human dental caries. Thus, we examined the inhibitory effects of Bifidobacterium spp. cells and culture supernatants against S. mutans and S. sobrinus, including Streptococcus gordonii, and Aggregatibacter actinomycetemcomitans, which is associated with periodontal disease.Methods: Mutans streptococci or A. actinomycetemcomitans and lactic acid bacteria (LAB) were mixed in 1:1 ratio and then incubated for 90min at 37°C. After the incubation, the viability of mutans streptococci or A. actinomycetemcomitans was determined by plate count technique. We also investigated the morphological... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285696 Sat, 01 Oct 2011 04:00:00 +0100 5285696 http://www.medworm.com/index.php?rid=5285695&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000628%2Fabstract%3Frss%3Dyes Abstract: The aim was to evaluate the presence of Staphylococcus spp., Enterobacteriaceae and Pseudomonadaceae in the oral cavities of HIV-positive patients. Forty-five individuals diagnosed as HIV-positive by ELISA and Western-blot, and under anti-retroviral therapy for at least 1 year, were included in the study. The control group constituted 45 systemically healthy individuals matched to the HIV patients to gender, age and oral conditions. Oral rinses were collected and isolates were identified by API system. Counts of microorganisms from HIV and control groups were compared statistically by a Mann–Whitney test (α=5%). The percentages of individuals positive for staphylococci were similar between the groups (p=0.764), whereas for Gram-negative rods, a higher percentage was observed a... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285695 Sat, 01 Oct 2011 04:00:00 +0100 5285695 http://www.medworm.com/index.php?rid=5285694&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911001270%2Fabstract%3Frss%3Dyes Abstract: Human third molar development is widely used to predict chronological age of sub adult individuals with unknown or doubted age. For these predictions, classically, the radiologically observed third molar growth and maturation is registered using a staging and related scoring technique. Measures of lengths and widths of the developing wisdom tooth and its adjacent second molar can be considered as an alternative registration. The aim of this study was to verify relations between mandibular third molar developmental stages or measurements of mandibular second molar and third molars and age. Age related performance of stages and measurements were compared to assess if measurements added information to age predictions from third molar formation stage. The sample was 340 orthopantomog... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285694 Sat, 01 Oct 2011 04:00:00 +0100 5285694 http://www.medworm.com/index.php?rid=5285693&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100118X%2Fabstract%3Frss%3Dyes Conclusions: Our findings may imply that the PAX9 A240P mutation is a risk factor for oligodontia in the Chinese population. A240P is likely to be a genetic cause of oligodontia though previous literature suggested it as a polymorphism only. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285693 Sat, 01 Oct 2011 04:00:00 +0100 5285693 http://www.medworm.com/index.php?rid=5285692&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000902%2Fabstract%3Frss%3Dyes Abstract: Enamel mineralisation is a highly controlled process in which the deposition, growth, and maturation of inorganic crystallites are regulated by secreted matrix proteins at the molecular and cellular level. Maxillary and mandibular first molars from the col1-caPPR mutants as well as normal controls aged for 12 weeks were observed by SEM and nanoindentation, respectively. Several types of aberrations in enamel distribution and crystal organisation were encountered in the transgenic molars. Also, the gene alteration resulted in degradation by as much as 23.42% in hardness and 17.56% in the elastic modulus. These data suggested that gene mutation altered the ameloblastic differentiation and movement, resulting in variations of crystal arrangement patterns, aberrations of enamel distr... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285692 Sat, 01 Oct 2011 04:00:00 +0100 5285692 http://www.medworm.com/index.php?rid=5285691&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000719%2Fabstract%3Frss%3Dyes Abstract: Objectives: the purpose of this study was to determine the mineral loss on surrounding enamel restored with glass ionomer cements (GIC) after erosive and cariogenic challenges.Methods: Bovine enamel specimens were randomly assigned into six groups according to the restorative material: G1 – composite resin; G2 – high viscous GIC; G3 – resin-modified glass ionomer with nanoparticles; G4 – encapsulated resin-modified GIC; G5 – encapsulated high viscous GIC; G6 – resin-modified GIC. After restorative procedures, half of specimens in each group were submitted to caries challenge using a pH cycling model for 5 days, and the other half were submitted to erosive challenge in citric acid for 10min. Before and after the challenges, surface Knoop microhardness assessments were ... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285691 Sat, 01 Oct 2011 04:00:00 +0100 5285691 http://www.medworm.com/index.php?rid=5285690&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100063X%2Fabstract%3Frss%3Dyes Conclusion: Maternal passive smoking inhibits the morphological development and mineralization level of hard tissue on the mandibular first molars of offspring rats. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285690 Sat, 01 Oct 2011 04:00:00 +0100 5285690 http://www.medworm.com/index.php?rid=5285689&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000616%2Fabstract%3Frss%3Dyes Conclusions: The mineral density, Ca and P weight percent decreased from the outer to the inner enamel layers in the two age groups. In the outer enamel layer, the differences in these properties between the two age groups were significantly different; however, no region-dependent differences were observed in the middle and inner enamel layers. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285689 Sat, 01 Oct 2011 04:00:00 +0100 5285689 http://www.medworm.com/index.php?rid=5285688&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000999%2Fabstract%3Frss%3Dyes This study investigated the effect of age, gender, number of natural teeth, occlusal force and salivary flow on the masticatory performance in a large sample of elderly adults.Design: The study sample consisted of 1288 independently living people aged 60–84 years. Masticatory performance was determined by the comminuted particles of test food. Bilateral maximal occlusal force in the intercuspal position was measured with pressure sensitive sheets. Stimulated whole saliva was collected.Results: Masticatory performance was significantly correlated to age, number of residual teeth, occlusal force and stimulated salivary flow rate by Pearson's correlation test. The multiple linear regression analysis showed that, with other variables controlled, masticatory performance was significantly asso... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285688 Sat, 01 Oct 2011 04:00:00 +0100 5285688 http://www.medworm.com/index.php?rid=5285687&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000951%2Fabstract%3Frss%3Dyes Conclusions: Oestrogen deficiency induces osteoclastogenesis in the alveolar healing process. Quantitative changes in the osteoclastic activity could be prevented through the raloxifene therapy. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285687 Sat, 01 Oct 2011 04:00:00 +0100 5285687 http://www.medworm.com/index.php?rid=5285686&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000665%2Fabstract%3Frss%3Dyes Conclusion: This study contributes to clarifying the effect of Pi on odontoblast viability and apoptosis, which may improve our understanding of the role of Pi during caries formation. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285686 Sat, 01 Oct 2011 04:00:00 +0100 5285686 http://www.medworm.com/index.php?rid=5285685&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000641%2Fabstract%3Frss%3Dyes Conclusion: Dentofacial deformity affected maximal isometric bite force regardless of its pattern. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285685 Sat, 01 Oct 2011 04:00:00 +0100 5285685 http://www.medworm.com/index.php?rid=5285684&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000604%2Fabstract%3Frss%3Dyes Conclusions: Despite lower strain magnitudes, the repetitive nature of rumination chewing makes it an important component of the mechanical loading environment of the selenodont artiodactyl jaw. However, similarities in principal strain orientations and ratios indicate that rumination chewing need not be considered as a unique loading behaviour influencing the biomechanics of the selenodont artiodactyl jaw. Differences in loading and chewing cycle durations during rumination and ingestion demonstrate flexibility in adult chewing frequencies. Finally, although the low within-sequence variability in chewing cycle durations supports the hypothesis that mammalian mastication is energetically efficient, chewing during rumination may not be more efficient than during ingestion. (Source: Archives... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285684 Sat, 01 Oct 2011 04:00:00 +0100 5285684 http://www.medworm.com/index.php?rid=5285683&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000872%2Fabstract%3Frss%3Dyes Abstract: Although the main reservoir of Candida spp. is believed to be the buccal mucosa, these microorganisms can coaggregate with bacteria in subgingival biofilm and adhere to epithelial cells. The treatment of periodontal disease includes scaling and root planning (SRP) associated with proper oral hygiene. However, some patients may have negative responses to different therapeutic procedures, with a continuous loss of insertion, so the use of antimicrobials is needed as an adjuvant to SRP treatment. The use of a broad-spectrum antibiotic, such as tetracycline and metronidazole, as an aid in periodontal treatment has also been a factor for the development of superinfections by resistant bacteria and Candida species, even in patients with HIV. In the dental practice, the most commonly us... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285683 Sat, 01 Oct 2011 04:00:00 +0100 5285683 http://www.medworm.com/index.php?rid=5285682&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000707%2Fabstract%3Frss%3Dyes Conclusions: Melatonin contributes to protecting of oral cavity from tissue damage due to its action of different receptors. From the reviewed literature it is concluded that experimental evidence suggests that melatonin can be useful in treating several common diseases of the oral cavity. Specific studies are necessary to extend the therapeutic possibilities of melatonin to other oral diseases. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285682 Sat, 01 Oct 2011 04:00:00 +0100 5285682 http://www.medworm.com/index.php?rid=5285681&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000690%2Fabstract%3Frss%3Dyes Abstract: The periodontal ligament (PDL) is a key contributor to the process of regeneration of the periodontium. The heterogeneous nature of the PDL tissue, its development during early adulthood, and the different conditions to which the PDL tissue is exposed to in vivo impart on the PDL unique characteristics that may be of consequence during its cultivation in vitro. Several factors affecting the in vivo setting influence the behaviour of PDL fibroblasts in culture. The purpose of this review is to address distinct factors that influence the behaviour of PDL fibroblasts in culture – in vivo–in vitro transitions, cell identification/isolation markers, primary PDL cultures and cell lines, tooth-specific factors, and donor-specific factors. Based on the reviewed studies, the authors r... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285681 Sat, 01 Oct 2011 04:00:00 +0100 5285681 http://www.medworm.com/index.php?rid=5285680&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002913%2Fabstract%3Frss%3Dyes (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5285680 Sat, 01 Oct 2011 04:00:00 +0100 5285680 http://www.medworm.com/index.php?rid=5109511&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000343%2Fabstract%3Frss%3Dyes Conclusion: MINO inhibits RANKL-induced osteoclastogenesis via down-regulation of NFATc1 mRNA expression in osteoclast precursor cells. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109511 Wed, 10 Aug 2011 17:12:41 +0100 5109511 http://www.medworm.com/index.php?rid=5109510&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000598%2Fabstract%3Frss%3Dyes Conclusions: The results of the present study suggest that none of the investigated biomaterials possesses antimicrobial properties against A. actinomycetemcomitans serotype b. Therefore, the use of these biomaterials for regenerative procedures should be weighted critically in the presence of A. actinomycetemcomitans serotype b. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109510 Wed, 10 Aug 2011 17:12:40 +0100 5109510 http://www.medworm.com/index.php?rid=5109509&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000513%2Fabstract%3Frss%3Dyes Conclusion: The results suggest that the clove oil and eugenol could be employed as a natural antibacterial agent against cariogenic and periodontopathogenic bacteria. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109509 Wed, 10 Aug 2011 17:12:39 +0100 5109509 http://www.medworm.com/index.php?rid=5109508&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000550%2Fabstract%3Frss%3Dyes This study evaluated the association amongst red complex, A. actinomycetemcomitans (A.a) and non-oral pathogenic bacteria in subjects with good periodontal health (PH), gingivitis (G), chronic (CP) and aggressive (AP) periodontitis.Methods: Subgingival biofilm samples were obtained from 51 PH, 42 G, 219 CP and 90 AP subjects. The presence and levels of A.a, red complex (Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola), Acinetobacter baumannii, Escherichia coli, Enterococcus faecalis, Pseudomonas aeruginosa, and Staphylococcus aureus were determined by DNA probes and DNA–DNA hybridization technique.Results: CP and AP subjects presented significantly higher prevalence and levels of A.a, red complex and A. baumannii than G and PH individuals (p (Source: Archives of Oral ... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109508 Wed, 10 Aug 2011 17:12:39 +0100 5109508 http://www.medworm.com/index.php?rid=5109507&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000549%2Fabstract%3Frss%3Dyes Conclusions: Tap-1 and Tapasin were downregulated in OSCC. IFN-γ increased the expression of these genes. Use of IFN-γ-antigen induced DCs could induce stronger immune response in vitro and in vivo. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109507 Wed, 10 Aug 2011 17:12:37 +0100 5109507 http://www.medworm.com/index.php?rid=5109506&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000537%2Fabstract%3Frss%3Dyes Abstract: Objective: MUC1 is primarily involved in the protection of epithelial surfaces. Decreases in oral mucosal defence can be a predisposing factor for the development of oral mucosal diseases in the elderly. The aim of this study was to compare MUC1 expression level in oral mucosal epithelial cells of the elderly with that of young adults.Design: Thirty elderly (mean age, 71.1±4.6 years) and thirty young (mean age, 26.4±2.4 years) adults (15 men and 15 women in each group) were included. Oral examination, including tooth, periodontal, and oral mucosal status, was performed and whole saliva samples were collected along with flow rate measurements. Precipitates of stimulated whole saliva were used for the evaluation of MUC1 expression using real-time PCR. Clarified supernatants were ... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109506 Wed, 10 Aug 2011 17:12:37 +0100 5109506 http://www.medworm.com/index.php?rid=5109505&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000306%2Fabstract%3Frss%3Dyes The objective of this study was to examine the TLR-9 expression and its role in tumour cell proliferation in oral squamous cell carcinoma.Materials and methods: Western blot and immunohistochemistry were used to detect TLR-9 protein in oral squamous cell carcinoma (OSCC) Tca-8113 cell lines and clinical specimens (n=60). The relationship between TLR-9 expression and clinicopathologic features was analysed. Cell proliferation and inflammatory chemokines secretion were tested by MTT and ELISA methods respectively.Results: Results showed that TLR-9 expression level was higher in OSCC tissues than in paired adjacent normal tissues (P (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109505 Wed, 10 Aug 2011 17:12:37 +0100 5109505 http://www.medworm.com/index.php?rid=5109504&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000501%2Fabstract%3Frss%3Dyes Conclusions: Together, our results demonstrate that hLF1–11 and P-113 display antibacterial activity against dental cavity-inducing S. mutans through an intracellular mechanism that could involve DNA binding. Thus, these peptides might be attractive and valuable candidates for development into effective antimicrobial therapies to combat dental caries. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109504 Wed, 10 Aug 2011 17:12:36 +0100 5109504 http://www.medworm.com/index.php?rid=5109503&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000495%2Fabstract%3Frss%3Dyes Conclusions: The results suggest an association of OLP with anxiety. However, DHEA and cortisol levels did not differ between groups, which does not support any neuroendocrine aetiology for OLP. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109503 Wed, 10 Aug 2011 17:12:36 +0100 5109503 http://www.medworm.com/index.php?rid=5109502&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000586%2Fabstract%3Frss%3Dyes Abstract: Inhibitory jaw reflexes are believed to be important for protecting the teeth and temporo-mandibular structures from damage during sudden or forceful biting or mastication. Accordingly, alterations in these reflexes are sometimes implicated in aetiologies proposed for oro-facial pain syndromes, although the association is not well-established. We now aim to develop a method for quantifying objectively inhibitory jaw reflexes evoked by natural tooth contact. In the longer term, this may provide a new approach to examining the association of altered reflexes and clinical conditions.Eighteen subjects gave their written, informed consent, and were recruited to participate in this study. They were instructed to clench their teeth together in response to visual cues. They performed two... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109502 Wed, 10 Aug 2011 17:12:35 +0100 5109502 http://www.medworm.com/index.php?rid=5109501&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000574%2Fabstract%3Frss%3Dyes Conclusion: Rapid fluid flow caused by thermal deformation of dentinal tubules may account for the short latency (10s) neural responses could be associated with the activation of thermo-sensitive receptors. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109501 Wed, 10 Aug 2011 17:12:35 +0100 5109501 http://www.medworm.com/index.php?rid=5109500&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000525%2Fabstract%3Frss%3Dyes Conclusions: Notch signalling plays a crucial role in regulating self-renewal and differentiation in DPSCs. The deficient Notch signalling inhibits the self-renewal capacity of DPSCs and tends to induce DPSCs differentiation under odontoblast differentiation-inducing conditions. These findings suggested that DPSCs/Delta1-RNAi might be applicable to stem cell therapies and tooth tissue engineering. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109500 Wed, 10 Aug 2011 17:12:34 +0100 5109500 http://www.medworm.com/index.php?rid=5109499&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000331%2Fabstract%3Frss%3Dyes Abstract: Bacterial biofilms in the mouth are prime mediators of the destruction of the dental and oral tissues. This brief review summarises recent work using a device for generating intact plaque in the mouth on natural enamel surfaces such that quantitative studies of mass transfer through natural plaque biofilms could be carried out in relation to plaque architecture. This data is discussed against the background of existing information. The device revealed complex plaque architecture with high a surface area to mass ratio decreasing from the exterior of the biofilm towards the tissue surface. Fluoride, a potent inhibitor of caries was concentrated in the outer regions of the biofilm. This implies some restriction of diffusion and possibly binding to the high surface area of the outer ... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109499 Wed, 10 Aug 2011 17:12:34 +0100 5109499 http://www.medworm.com/index.php?rid=5109498&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002317%2Fabstract%3Frss%3Dyes (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5109498 Wed, 10 Aug 2011 17:12:34 +0100 5109498 http://www.medworm.com/index.php?rid=5039652&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000264%2Fabstract%3Frss%3Dyes Abstract: Objectives: The aim of this study was to compare the levels of cytokines IL-6, IL-10 and IL-17 and the chemokine IL-8 in the peri-implant crevicular fluid (PCF) between the group of patients with peri-implantitis (PP) and peri-implantar healthy patients (HP).Design: The PCF was collected from 40 implants regarding 25 patients, being 14 patients with PP and 11 HP totalizing 20 implants from each group. The PCF samples collected from each patient were quantified for IL-6, IL-17, IL-8 and IL-10 using the enzymatic immunosorbent assay (ELISA).Results: The expression of IL-17 was significantly higher in the PP group when compared to HP (p (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039652 Wed, 20 Jul 2011 16:01:05 +0100 5039652 http://www.medworm.com/index.php?rid=5039651&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000215%2Fabstract%3Frss%3Dyes Conclusions: High and low concentrations (10−3–10−5M) of these AOs (RFT, PFR) may have beneficial effects on functional mechanisms regulating fibroblast migration and proliferation during gingival healing or periodontal repair. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039651 Wed, 20 Jul 2011 16:01:04 +0100 5039651 http://www.medworm.com/index.php?rid=5039650&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691000381X%2Fabstract%3Frss%3Dyes Conclusion: CP is more severe and is associated with increased frequency of C. albicans, P. gingivalis, T. forsythia, and T. denticola in patients with CKD. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039650 Wed, 20 Jul 2011 16:01:04 +0100 5039650 http://www.medworm.com/index.php?rid=5039649&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100032X%2Fabstract%3Frss%3Dyes Abstract: Objective: To analyse the effect of integrated orthodontic treatment, orthognathic surgery and orofacial myofunctional therapy on masseter muscle thickness in patients with class III dentofacial deformity three years after orthognathic surgery.Design: A longitudinal study was conducted on 13 patients with class III dentofacial deformities, denoted here as group P1 (before surgery) and group P3 (same patients 3 years to 3 years and 8 months after surgery). Fifteen individuals with no changes in facial morphology or dental occlusion were assigned to the control group (CG). Masseter muscle ultrasonography was performed in the resting and biting situations in the three groups. Data were analysed statistically by a mixed-effects linear model considering a level of significance of P (S... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039649 Wed, 20 Jul 2011 16:01:04 +0100 5039649 http://www.medworm.com/index.php?rid=5039648&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS000399691100029X%2Fabstract%3Frss%3Dyes Abstract: Previous studies have investigated the effects of increasing the occlusal vertical dimension (OVD) with an oral appliance on masticatory muscle EMG activity during oral behaviours in humans and animals. The present study investigated whether a short-term and reversible increase in OVD, followed by a reduction in OVD to the normal level, resulted in a time-correlated change in the EMG activities of the masseter and digastric muscles during chewing. To do this, a guinea pig model in which an increased OVD was established with natural tooth contacts was used. In the control group, in which no bite-raising treatment was applied, OVD gradually increased with a natural growth during the experimental period whilst the masseter and digastric EMG activities, burst duration, and chewing rh... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039648 Wed, 20 Jul 2011 16:01:03 +0100 5039648 http://www.medworm.com/index.php?rid=5039647&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000239%2Fabstract%3Frss%3Dyes Conclusions: Our study provides strong support for the hypothesis that in the European roe deer the prenatal and early postnatal (pre-weaning) stages of dental development are (largely) protected against exposure to excess fluoride. This is attributed to the operation of certain protective mechanisms during these periods. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039647 Wed, 20 Jul 2011 16:01:03 +0100 5039647 http://www.medworm.com/index.php?rid=5039646&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000227%2Fabstract%3Frss%3Dyes Abstract: Objective: Some saliva substitutes have been shown to demineralize dentine in vitro. This effect is counteracted by the application of various fluorides. In contrast, remineralizing saliva substitutes might be supported by these treatments, depending on the dynamics during remineralization. The aim of this in vitro study was to evaluate the effects of fluoride mouthrinses or gels in combination with de-/remineralizing saliva substitutes on dentinal subsurface lesions. Design: Demineralized bovine dentine specimens were stored either in mineral water [saturation with respect to octacalcium phosphate (SOCP): 0.7], Glandosane (G, SOCP: 0.3) or in a modified saliva substitute Saliva natura (SN, SOCP: 1.9) for five weeks (37°C). Fluoride agents were applied twice daily for 10min (n=1... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039646 Wed, 20 Jul 2011 16:01:03 +0100 5039646 http://www.medworm.com/index.php?rid=5039645&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000288%2Fabstract%3Frss%3Dyes Abstract: Objective: The purpose of the present study was to investigate the effects of exercise training on serum reactive oxygen species (ROS) level and gingival oxidative stress in obese rats fed a high-fat diet.Design: Rats were divided into three groups (n=14/group): one control group (fed a regular diet) and two experimental groups (fed a high-fat diet with and without exercise training [treadmill: 5 days/week]). The rats were sacrificed at 4 or 8 weeks. The level of serum reactive oxidative metabolites (ROM) was measured as an indicator of circulating ROS. The level of 8-hydroxydeoxyguanosine (8-OHdG) and reduced-form glutathione (GSH)/oxidised-form glutathione (GSSG) ratio were determined to evaluate gingival oxidative stress.Results: The obese rats fed a high-fat diet without exer... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039645 Wed, 20 Jul 2011 16:01:02 +0100 5039645 http://www.medworm.com/index.php?rid=5039644&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000240%2Fabstract%3Frss%3Dyes Abstract: In the oral cavity, mucosal keratinocytes resist bacterial infection, in part, by producing broad-spectrum antimicrobial peptides (AMPs) including defensin, adrenomedullin and calprotectin. Epidermal keratinocyte expression of many AMPs increases in response to interleukin-1α (IL-1α). IL-1α is produced by epidermal keratinocytes and regulates cell differentiation. To better understand innate immunity in the oral cavity, we sought to determine how IL-1α might regulate expression of AMPs by human gingival keratinocytes (HGKs) using DNA microarray and Western blot analyses. HGKs from three subjects expressed eleven AMPs, including S100A7, S100A8, S100A9, S100A12, secretory leucocyte protease inhibitor, lipocalin 2 (LCN2), cystatin C and β-defensin 2. Of the expressed AMPs, S100... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039644 Wed, 20 Jul 2011 16:01:02 +0100 5039644 http://www.medworm.com/index.php?rid=5039643&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000057%2Fabstract%3Frss%3Dyes Abstract: Objective: To evaluate the immunohistochemical expression of MMP-1, -2, -7, -9 and -26 in oral squamous cell carcinomas (SCCs) according to tumour site and histological grade of malignancy.Study design: Fifteen cases of SCC of the lower lip and 15 cases of tongue SCC were selected and divided into low grade malignancy (n=17) and high grade malignancy (n=13).Results: Higher immunohistochemical expression of MMPs by neoplastic cells was observed in tongue SCCs, with a statistically significant difference for MMP-9 (P (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039643 Wed, 20 Jul 2011 16:01:02 +0100 5039643 http://www.medworm.com/index.php?rid=5039642&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000252%2Fabstract%3Frss%3Dyes Conclusions: These results suggest that the diabetic state influences the type I collagen concentration in the parotid glands of rats. In addition, acarbose treatment was helpful in preventing the deposition of such fibres, as well the increase in oxidative stress induced by hyperglycemia. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039642 Wed, 20 Jul 2011 16:01:01 +0100 5039642 http://www.medworm.com/index.php?rid=5039641&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996910003845%2Fabstract%3Frss%3Dyes Summary: Aim: To study the protective effect of tea polyphenols (TPs) on submandibular glands affected by radiation injury.Methods: Sixty rats were randomly divided into radiation group (R-group, N=30) and TP-pre-treated-radiation group (TPR-group, N=30). The rats were intragastrically administered with TP or normal sodium from 14 days before radiation, continuously daily, until the experiment. All the rats in both groups were irradiated with a single exposure dose of 15Gy gamma rays that were delivered to the head and neck areas. Ten rats of each group were anatomised on the 3rd, 6th and 30th day after irradiation, respectively. The submandibular glands of the rats were removed for the study. The morphologic changes of the submandibular glands were observed by transmission electron micros... Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039641 Wed, 20 Jul 2011 16:01:01 +0100 5039641 http://www.medworm.com/index.php?rid=5039640&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911000276%2Fabstract%3Frss%3Dyes Conclusions: No consistent evidence emerged of a strong association between risk of OFCs and any known gene related to folate metabolism. Further, recent genome-wide association studies have not identified associations between OFCs and folate-related genes. Further studies are warranted to determine whether gene–environment interactions, including gene–nutrient interactions and epigenetic modifications of genes affect the risk of OFCs. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039640 Wed, 20 Jul 2011 16:01:01 +0100 5039640 http://www.medworm.com/index.php?rid=5039639&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996911002147%2Fabstract%3Frss%3Dyes (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=5039639 Wed, 20 Jul 2011 16:01:01 +0100 5039639 http://www.medworm.com/index.php?rid=4946592&cid=s_34395_11_f&fid=34395&url=http%3A%2F%2Fwww.aobjournal.com%2Farticle%2FPIIS0003996910003833%2Fabstract%3Frss%3Dyes Conclusions: This study provides evidence that different types of dental MSCs can be used in tissue engineering/regeneration protocols as an approachable stem cell source for osteo/odontogenic differentiation and biomineralization that could be further applied for stem cell-based clinical therapies. (Source: Archives of Oral Biology) Archives of Oral Biology journals http://www.medworm.com/rss/comments.php?id=4946592 Mon, 20 Jun 2011 16:40:11 +0100 4946592