MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Arquivos de Gastroenterologia' source. Thu, 02 Feb 2012 16:30:02 +0100 http://www.medworm.com/index.php?rid=5469641&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400012%26lng%3Den%26nrm%3Diso%26tlng%3Den This study investigated changes in intestinal villi heights and crypts depths due to surgical techniques: seromiotomy with and without omentoenteropexy. METHOD: Thirty rats were operated on, after being divided into three groups, namely GI, GII and GIII with 10 rats each. In the GI rats were submitted to omentoenteropexy; rats in GII were submitted only to a seromiotomy, and in the GIII only laparotomy. Sixty days after the first surgery, the animals were sacrificed and a segment of intestine was removed for histology using Masson's trichrome technique and morphometric study of intestinal mucosa. RESULTS: The histological findings showed that seromiotomy with or without omentoenteropexy increased the length of intestinal villi when compared with GIII (only laparotomy) (analysis of variance... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469641 Sun, 04 Dec 2011 09:45:50 +0100 5469641 http://www.medworm.com/index.php?rid=5469640&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The AEB demonstrated good antiulcerogenic activities which justify the inclusion of this plant in the management of gastric disorders. Further experiments are underway to determine which antiulcer mechanisms involved in gastroprotection.CONTEXTO: O repolho (Brassica oleracea var. capitata) é uma planta de folhas herbáceas pertencente à família Brassicaceae, nativa na costa sul e oeste da Europa. Usado na culinária por seu valor nutritivo, possui conhecida atividade anti-inflamatória. OBJETIVO: Avaliar a atividade antiulcerogênica do extrato aquoso de Brassica oleracea var. capitata (AEB), a fim de validar os conhecimentos etnobotânico do uso da espécie em distúrbios gástricos. MÉTODO: Úlceras gástricas foram induzidas em ratos pela administração oral de ácido ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469640 Sun, 04 Dec 2011 09:45:50 +0100 5469640 http://www.medworm.com/index.php?rid=5469639&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Locally advanced carcinomas were found in 13.2% of patients. Survival rates were negatively affected by rectal location and adverse histological features. Number of involved organs and neoplastic adhesions did not influenced chances of survival. A radical R0 extended resection was achieved in a high proportion of cases, resulting in a 60% cancer-free survival under acceptable operative risks.OBJETIVOS: Avaliar a incidência, os resultados operatórios e os fatores prognósticos relacionados aos tumores colorretais localmente avançados. MÉTODOS: A população deste estudo foi constituída por 679 pacientes com câncer colorretal tratados entre 1997 e 2007. Dados clínicos, cirúrgicos e histológicos foram analisados. RESULTADOS: Noventa pacientes (mulheres 61%; idade media 5... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469639 Sun, 04 Dec 2011 09:45:50 +0100 5469639 http://www.medworm.com/index.php?rid=5469638&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: The correlation between vaginal delivery, age and pelvic floor dysfunctions involving obstructed defecation is still a matter of controversy. OBJECTIVES: To determine the influence of age, mode of delivery and parity on the prevalence of posterior pelvic floor dysfunctions in women with obstructed defecation syndrome. METHODS: Four hundred sixty-nine females with obstructed defecation syndrome were retrospectively evaluated using dynamic 3D ultrasonography to quantify posterior pelvic floor dysfunctions (rectocele grade II or III, rectal intussusception, paradoxical contraction/non-relaxation of the puborectalis and entero/ sigmoidocele grade III). In addition, sphincter damage was evaluated. Patients were grouped according to age ( Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469638 Sun, 04 Dec 2011 09:45:50 +0100 5469638 http://www.medworm.com/index.php?rid=5469637&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Due to the low amoxicillin and clarithromycin resistance observed in this study, therapies using these antimicrobials remain appropriated first-line H. pylori therapy.CONTEXTO: A susceptibilidade aos antibióticos é a pedra fundamental dos tratamentos de erradicação do Helicobacter pylori. OBJETIVO: Avaliar a prevalência da resistência primária do H. pylori aos antibióticos em uma população urbana do Brasil. MÉTODOS: As cepas do H. pylori foram obtidas de pacientes submetidos a endoscopia digestiva para avaliação de sintomas dispépticos. Biopsias do antro, corpo e fundo gástrico foram realizadas para determinar a susceptibilidade das cepas do H. pylori aos antibióticos. A concentração inibitória mínima da furazolidona e do bismuto foram determinadas rotineira... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469637 Sun, 04 Dec 2011 09:45:50 +0100 5469637 http://www.medworm.com/index.php?rid=5469636&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The partial fundoplication has lower incidence of obstructive side effects.CONTEXTO: Apesar da alta incidência da doença do refluxo gastroesofágico (DRGE) na população em geral, ainda existe muita controvérsia sobre este assunto, especialmente quanto ao tratamento cirúrgico. A decisão de usar fundoplicatura total ou parcial no tratamento da DRGE ainda é um desafio para muitos cirurgiões devido à pouca evidência disponível na literatura. OBJETIVO: Comparar a fundoplicatura total e as fundoplicaturas parciais no tratamento da DRGE, avaliando a eficácia das duas técnicas operatórias. MÉTODO: Foram utilizadas a revisão sistemática da literatura e metanálise de estudos prospectivos e randomizados. Fontes de informação utilizadas: LILACS, MEDLINE, Cochrane Contr... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469636 Sun, 04 Dec 2011 09:45:50 +0100 5469636 http://www.medworm.com/index.php?rid=5469635&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: There was no significant difference in bacteremia rate between these three groups. BL or CY injection for non-bleeding esophageal varices may be considered as low-risk procedures regarding bacteremia even when performed on patients with advanced liver disease.CONTEXTO: A ligadura elástica é considerada o melhor tratamento endoscópico para o sangramento agudo por varizes esofágicas ou para profilaxia do sangramento varicoso, sendo a escleroterapia com N-2-butil-cianoacrilato uma alternativa para os pacientes com doença hepática avançada e distúrbio de coagulação. Bacteriemia é uma complicação rara associada à ligadura elástica, por outro lado, a incidência de bacteriemia relacionada com o uso de N-2-butil-cianoacrilato permanece desconhecida. OBJETIVOS: Avaliar ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469635 Sun, 04 Dec 2011 09:45:50 +0100 5469635 http://www.medworm.com/index.php?rid=5469634&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Endoscopic mucosal resection is a minimally invasive technique used in the treatment of colorectal neoplasms, including early carcinomas of different size and morphology. OBJECTIVES: To evaluate procedure safety, efficacy, outcomes, and recurrence rate in endoscopic mucosal resection of colorectal lesions. METHODS: A total of 172 lesions in 156 patients were analyzed between May 2003 and May 2009. All lesions showed pit pattern suggestive of neoplasia (Kudo types III-V) at high-magnification chromocolonoscopy with indigo carmine. The lesions were evaluated for macroscopic classification, size, location, and histopathology. Lesions 20 mm or smaller were resected en bloc and lesions larger than 20 mm were removed using the piecemeal technique. Complications and recurrence were analy... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469634 Sun, 04 Dec 2011 09:45:50 +0100 5469634 http://www.medworm.com/index.php?rid=5469633&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400004%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Endoscopy has high sensitivity and low specificity for subepithelial tumor and both are low for the extrinsic compression. Endoscopy is a good tool for diagnosis of the subepithelial tumors, but not to determine the cause of an extrinsic compression. The endosonography identifies the layer from which subepithelial tumor comes, obtain histological samples, and increasing the diagnostic accuracy.CONTEXTO: Abaulamentos da parede do trato gastrointestinal cobertos por epitélio normal são achados comuns durante endoscopia digestiva alta. OBJETIVOS: Comparar os achados da endoscopia com os da ecoendoscopia no diagnóstico diferencial entre tumor subepitelial e compressão extrínseca. MÉTODO: Estudaram-se, retrospectivamente, pacientes com abaulamento do trato gastrointestinal alt... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469633 Sun, 04 Dec 2011 09:45:50 +0100 5469633 http://www.medworm.com/index.php?rid=5469632&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Although procedure duration was longer in the "introducer" PEG-gastropexy, infection scores were marginally higher in the "pull" PEG technique.CONTEXTO: A nutrição enteral está indicada para pacientes incapazes de manter aporte voluntário adequado e a gastrostomia endoscópica percutânea (GEP) é a via preferencial para acesso enteral de longa duração. As infecções periostomais são as principais complicações da GEP, ocorrendo em até 8% dos pacientes, a despeito do uso de antibiótico profilático. A GEP pela técnica de introdução com gastropexia evita a passagem da sonda de gastrostomia pela cavidade oral, prevenindo contra o deslocamento de microorganismos ali presentes até o sítio da ostomia. OBJETIVO: Comparar a incidência de infecção periostomal no 7º ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469632 Sun, 04 Dec 2011 09:45:50 +0100 5469632 http://www.medworm.com/index.php?rid=5469631&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400002%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: No endoscopic or histopathologic finding was pathognomonic. One percent of duodenal endoscopic biopsies showed parasites.CONTEXTO: Parasitas intestinais podem induzir alterações histopatológicas, que têm sido estudadas em subgrupos com diagnóstico firmado de parasitose. Não há estudo disponível com base mais ampla, sem diagnóstico prévio. OBJETIVO: Descrever os achados clínicos e histopatológicos de parasitoses diagnosticadas por biopsia em pacientes submetidos a endoscopia digestiva alta. MÉTODO: Laudos de biopsias realizadas de janeiro de 1995 a janeiro de 2009, no Complexo Hospitalar Professor Edgar Santos, hospital geral universitário localizado no nordeste brasileiro, foram revisados. Mil e dez laudos de biopsia duodenal foram revistos. Biopsias positivas pa... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469631 Sun, 04 Dec 2011 09:45:50 +0100 5469631 http://www.medworm.com/index.php?rid=5469630&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000400001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5469630 Sun, 04 Dec 2011 09:45:50 +0100 5469630 http://www.medworm.com/index.php?rid=5261633&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300013%26lng%3Den%26nrm%3Diso%26tlng%3Den Capsule endoscopy is a diagnostic method of increasing use nowadays, with various applications such as, evaluation of obscure gastrointestinal bleeding, chronic diarrhea and anemia. The experience of 4 years is reported in a retrospective review of 109 medical records to determine the main indications and the most common diagnostic findings and the percentage of positive studies. The main indications were obscure bleeding in 65%, chronic anemia in 8%. Vascular lesions in 33%, being that, hematocistic spot was found in 53% of studies. The location of active bleeding was possible in five patients (4.5%). Capsule endoscopy shows a high diagnostic yield in obscure bleeding.A endoscopia por cápsula é um método cada vez mais empregado na prática clínica, com diversas aplicações tais como:... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261633 Thu, 29 Sep 2011 08:34:04 +0100 5261633 http://www.medworm.com/index.php?rid=5261632&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: In any case, hilar lymph node dissection has been shown to be a useful tool for improving the accuracy of extra hepatic disease staging, regardless of its impact on survival.CONTEXTO: A hepatectomia é o tratamento de eleição para metástases hepáticas de câncer colorretal e diversos estudos têm demonstrado bons resultados, com índices de sobrevida em 5 anos entre 40% e 57%. Vários fatores clínico-patológicos preditivos de sobrevida após a ressecção hepática têm sido estudados e o envolvimento linfonodal do hilo hepático, que varia entre 2% e 10%, confere a este grupo prognóstico reservado a longo prazo. RESULTADOS: Embora com resultados variáveis, alguns autores têm relatado sobrevida não desprezível em pacientes com metástases hepáticas associada à doen... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261632 Thu, 29 Sep 2011 08:34:04 +0100 5261632 http://www.medworm.com/index.php?rid=5261631&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Portal hypertension is a complication secondary to cirrhosis that is characterized by increased blood flow and/or vascular resistance in the portal system, causing the appearance of a hyperdynamic collateral circulation. Partial portal vein ligation is an experimental model used in rats to study the pathophysiological mechanisms involved in pre-hepatic portal hypertension. Estrogen E2 is an antioxidant molecule with various physiological actions. OBJECTIVES: To evaluate the antioxidant activity of endogenous estrogen in an experimental model of partial portal vein ligation by comparing intact with castrated rats. METHODS: Twenty Wistar rats, weighing on average 250 g were used and divided into four groups: sham-operated (SO); intact (I) with partial portal vein ligation (I + PPVL)... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261631 Thu, 29 Sep 2011 08:34:04 +0100 5261631 http://www.medworm.com/index.php?rid=5261630&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: The inflammatory response itself and the consequent oxidative stress are able to promote neurodegeneration. So, it is possible that enteric nervous system is affected by inflammatory diseases threatening quality of life of patients. However, gastrointestinal symptoms of arthritis are usually attributed to anti-inflammatory drugs rather than neural damage. OBJECTIVE: To confirm if the general population of myenteric neurons from the ileum and jejunum of rats is affected by arthritis. METHODS: Twenty Holtzmann rats, 58-day-old male, were used and divided in four groups: control group (C30), arthritic group (Art30), older control group (C60) and older arthritic group (Art60). At 58 days old, the animals in groups Art30 and Art60 received an injection of the complete Freund's adjuvant... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261630 Thu, 29 Sep 2011 08:34:04 +0100 5261630 http://www.medworm.com/index.php?rid=5261629&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: In order to cause diarrhea, enteroaggregative Escherichia coli strains adhere to the intestinal mucosa, create a mucoid biofilm on the small bowel surface that could justify the digestive-absorptive abnormalities and consequently, prolonging the diarrhea.CONTEXTO: Cepas de Escherichia coli enteroagregativa têm sido associadas à diarreia persistente em vários países em desenvolvimento. Procedimentos in vivo com modelos animais, cultura de órgão in vitro com fragmentos intestinais e ensaios in vitro com linhas celulares têm sido utilizados para estudar essas bactérias e a sua patogenicidade. OBJETIVO: A presente investigação experimental avaliou as interações patogênicas de três cepas de Escherichia coli enteroagregativa, usando cultura de órgão in vitro, para mos... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261629 Thu, 29 Sep 2011 08:34:04 +0100 5261629 http://www.medworm.com/index.php?rid=5261628&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Age and gender influence swallowing behavior, with the effect of gender being more evident in younger subjects and the effect of age being more evident in men.CONTEXTO: Idade e, possivelmente, o gênero afetam a dinâmica da deglutição. Entretanto, a interação entre os efeitos da idade e do gênero na deglutição não é completamente conhecida. OBJETIVO: Avaliar a possível interação da idade e do gênero na dinâmica da deglutição. MÉTODOS: A dinâmica da deglutição foi avaliada pelo teste de ingestão de água em 89 voluntários saudáveis, 43 homens e 46 mulheres, com idades de 20 a 40 anos (jovens, n = 38), 41-60 anos (meia idade, n = 31) e 61 a 80 anos (idosos, n = 20). Cada sujeito ingeriu em triplicata 50 mL de água enquanto eram medidos o tempo de ingestã... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261628 Thu, 29 Sep 2011 08:34:04 +0100 5261628 http://www.medworm.com/index.php?rid=5261627&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: The correct diagnosis and effective treatment of Helicobacter pylori gastric infection are essential in controlling this infection. OBJECTIVE: To compare the diagnostic value of three tests based in endoscopic gastric biopsies histopathological evaluation with hematoxylin-eosin (H-E) staining, urease rapid test and microbiological culture for detecting Helicobacter pylori active infection, in order to make recommendations for daily clinical practice. METHODS: Gastric biopsies from 115 adult patients (85 female/30 male) were obtained by upper gastrointestinal endoscopy and studied by histopathological evaluation with H-E (antrum-corpus), urease test in 2 hours (antrum) and microbiological culture (antrum). RESULTS: Helicobacter pylori active infection was diagnosed in 67% of patien... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261627 Thu, 29 Sep 2011 08:34:04 +0100 5261627 http://www.medworm.com/index.php?rid=5261626&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: A link could be identified between hypothyroidism and markers of glucose and lipid homeostasis, but not with severity of NAFLD. The lack of correlation with liver biopsy requires further studies.CONTEXTO: Os hormônios tireoidianos podem interferir na regulação do metabolismo de lipídios e carboidratos e também na gravidade da doença hepática gordurosa não-alcoólica (DHGNA), porém os resultados ainda são debatidos. OBJETIVOS: Avaliar retrospectivamente correlações clínicas e metabólicas entre hipotireoidismo e DHGNA. MÉTODOS: Em 103 pacientes com DHGNA confirmada por biopsia e também hipotireoidismo recebendo tratamento, procedeu-se à investigação clínica, bioquímica e histológica. RESULTADOS: A esteatose foi observada em 32,0% e a esteatohepatite não-alc... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261626 Thu, 29 Sep 2011 08:34:04 +0100 5261626 http://www.medworm.com/index.php?rid=5261625&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: In the evaluated patients the presence of liver steatosis did not influence the sustained virological response of patients with chronic hepatitis C treated with interferon and ribavirin.CONTEXTO: Tanto a hepatite crônica pelo vírus C quanto a doença hepática gordurosa não-alcoólica são reconhecidas como causas frequentes de doença hepática nos países ocidentais. É comum observar a concomitância das duas doenças e a influência da esteatose na resposta virológica sustentada dos pacientes com hepatite crônica pelo vírus C. OBJETIVO: Avaliar a resposta virológica sustentada nos pacientes com hepatite crônica pelo vírus C de acordo com a presença de esteatose. MÉTODOS: Foram avaliados, retrospectivamente, 160 pacientes com hepatite crônica C. Dados demográfic... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261625 Thu, 29 Sep 2011 08:34:04 +0100 5261625 http://www.medworm.com/index.php?rid=5261624&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300004%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Most patients subjected to liver transplantation presents hypersplenism, which is reversed after the operation. However, some patients remain with moderate to intense hypersplenism. OBJECTIVES: To study the effect of liver transplantation on platelet count in patients with hypersplenism. METHOD: Of a total of 233 patients who underwent liver transplantation, 162 were excluded from the present study because of occurrence of steroid-resistant rejection, absence of hypersplenism before the transplantation, absence of follow-up for at least 2 years or incomplete exams data. The electronic study protocols of the remaining 71 patients were reviewed to determine the demographics, etiology of cirrhosis, and results of pathologic examination of the explanted liver. Serial platelet count wa... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261624 Thu, 29 Sep 2011 08:34:04 +0100 5261624 http://www.medworm.com/index.php?rid=5261623&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: In spite of Helicobacter pylori infection being the etiological cause of peptic ulcer and its high prevalence in Brazil, the prevalence of peptic ulcer disease has been poorly studied. OBJECTIVES: To verify the peptic ulcer disease prevalence in patients of a tertiary care hospital. METHODS: Diagnostic findings from 1,478 consecutive endoscopies were correlated with the urease test results for H. pylori infection diagnosis and demographic data in a total of 3,779 endoscopies performed in 2005. The mean age of the patients was 51.14 ± 16.46, being 613 (41.5%) men. RESULTS: Peptic ulcer was diagnosed in 494 (33.4%) patients with a mean age of 54.86 ± 14.53, 205 (52%) were men, being 391 (26.5%) duodenal ulcer and 103 (7%) gastric ulcer. Normal endoscopy was found in 272 (18.4%) pa... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261623 Thu, 29 Sep 2011 08:34:04 +0100 5261623 http://www.medworm.com/index.php?rid=5261622&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300002%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The use of FICE improves the diagnosis of minimal lesions as compared to conventional videoendoscopy, although this diagnosis remains observer-dependent. There was no association between the presences of minimal lesions with reflux symptoms.CONTEXTO: A doença do refluxo gastroesofágico é muito prevalente no mundo. Endoscopicamente pode ser classificada como não-erosiva quando não há lesões erosivas da mucosa à endoscopia. A presença de lesões mínimas à endoscopia está incluída na classificação de Los Angeles para a doença do refluxo. A cromoendoscopia virtual "Fuji Intelligent Color Enhancement" (FICE) é uma técnica endoscópica que melhora a detecção de lesões pequenas do trato digestório. OBJETIVO: Avaliar se o uso de FICE melhora o diagnóstico de les... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261622 Thu, 29 Sep 2011 08:34:04 +0100 5261622 http://www.medworm.com/index.php?rid=5261621&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000300001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5261621 Thu, 29 Sep 2011 08:34:04 +0100 5261621 http://www.medworm.com/index.php?rid=5031173&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: While significant progress has been made in the islets transplantation field, many obstacles remain to be overcome. Microencapsulation provides a means to transplant islets without immunosuppressive agents and may enable the performance of xenotransplantation. The use of alternative donor sources, fewer islets per capsule and the appropriate deployment location, such as the peritoneal cavity, may give a future perspective to the application of immunoprotective capsules and viability in clinical practice. A variety of strategies, such as genetic engineering, co-encapsulation, improvement in oxygen supply or the establishment of hypoxia resistance will also improve the islet transplantation performance. It remains to be determined which combination of strategies with encapsulatio... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=5031173 Sat, 16 Jul 2011 17:15:45 +0100 5031173 http://www.medworm.com/index.php?rid=4955103&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200014%26lng%3Den%26nrm%3Diso%26tlng%3Den Both celiac disease and scleroderma have autoimmune etiology and affect the bowel causing diarrhea. As an association of autoimmune disease in a single individual is not rare, it is important to know if a patient with scleroderma may also have celiac disease. To analyze this we studied 105 scleroderma patients and 97 volunteers for IgA-EmA by indirect immunofluorescence assay. We could not find a higher prevalence of this autoantibody in scleroderma patients. The authors conclude that there is no need to screen scleroderma patients with diarrhea for celiac disease unless there is a clear clinical indication for this.Tanto a esclerodermia como a doença celíaca são doenças de autoimunidade que causam diarreia. Como o agrupamento de doenças autoimunes em único indivíduo não é raro, Ã... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955103 Wed, 22 Jun 2011 17:46:13 +0100 4955103 http://www.medworm.com/index.php?rid=4955102&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The endoscopic repair using T-tag and a protector chamber is feasible, easy to perform and safe. Further studies are needed to show the real value of this kind of procedure.CONTEXTO: A perfuração gástrica pode ser consequência de alguns procedimentos endoscópicos, atualmente, produzida intencionalmente para acesso a alguns órgãos com o advento da cirurgia transluminal endoscópica por orifícios naturais. Esta é a razão para que os endoscopistas estudem uma maneira segura de reparar estas lesões por via endoscópica. OBJETIVO: Avaliar um novo método de fechamento das perfurações gástricas utilizadas para acesso ao NOTES. MODELO DE ESTUDO: Pesquisa em modelos animais com curto tempo de sobrevida. MÉTODO: Dez porcos da raça White Landrace, foram submetidos a perfu... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955102 Wed, 22 Jun 2011 17:46:13 +0100 4955102 http://www.medworm.com/index.php?rid=4955101&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Hypercaloric and hyperlipidic diet rich in polyunsaturated fat promotes weight gain and favors the development of hepatic steatosis while reducing serum levels of triglycerides, total cholesterol and HDL.CONTEXTO: A doença hepática gordurosa não-alcoólica caracteriza-se por depósito de lipídios nos hepatócitos. Desperta grande interesse por sua associação com obesidade, dislipidemias e diabetes mellitus tipo 2. É considerada a manifestação hepática da síndrome metabólica, cujo principal componente é a resistência à insulina, com consequente hiperinsulinemia e produção aumentada de citocinas inflamatórias. Dietas ricas em gorduras saturadas promovem hipertrigliceridemia, diminuição do colesterol de alta densidade, aumento do colesterol de baixa densidade e... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955101 Wed, 22 Jun 2011 17:46:13 +0100 4955101 http://www.medworm.com/index.php?rid=4955100&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: While significant progress has been made in the islets transplantation field, many obstacles remain to be overcome. Microencapsulation provides a means to transplant islets without immunosuppressive agents and may enable the performance of xenotransplantation. The use of alternative donor sources, fewer islets per capsule and the appropriate deployment location, such as the peritoneal cavity, may give a future perspective to the application of immunoprotective capsules and viability in clinical practice. A variety of strategies, such as genetic engineering, co-encapsulation, improvement in oxygen supply or the establishment of hypoxia resistance will also improve the islet transplantation performance. It remains to be determined which combination of strategies with encapsulatio... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955100 Wed, 22 Jun 2011 17:46:13 +0100 4955100 http://www.medworm.com/index.php?rid=4955099&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: High-resolution anoscopy demonstrated to be a sensitive, but not specific test for the detection of anal squamous intraepithelial lesions. Risk factors anal receptive sex and anal HPV infection were significantly associated to the presence of anal squamous intraepithelial lesions. Based on high-resolution anoscopy image data, acetowhite lesions relief and surface pattern were prone to distinguish between low-grade squamous intraepithelial lesions and high-grade squamous intraepithelial lesions.CONTEXTO: O câncer anal, muito embora ainda seja uma doença rara, vem sendo observado com frequência ascendente em alguns grupos populacionais considerados sob risco para o desenvolvimento da doença. Infecção pelo vírus do papiloma humano (HPV), imunossupressão e o sexo anorecepti... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955099 Wed, 22 Jun 2011 17:46:13 +0100 4955099 http://www.medworm.com/index.php?rid=4955098&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: High prevalence of celiac disease among siblings of patients with confirmed celiac disease necessitates serologic screening (and confirmatory biopsy if indicated) in families having celiac disease. It is advantageous to diagnose the disease as soon as possible because early diagnosis and diet intervention may prevent serious complications such as growth retardation, short stature, chronic diarrhea, and malignancy.CONTEXTO: A doença celíaca, uma das mais conhecidas enfermidades autoimunes humanas, leucocitária antígeno-dependente, tem prevalência relativamente maior em parentes de primeiro grau. OBJETIVO: Determinar a prevalência de doença celíaca em irmãos de pacientes confirmadamente celíacos, filhos dos mesmos pais. MÉTODOS: Os irmãos de pacientes com doença celÃ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955098 Wed, 22 Jun 2011 17:46:13 +0100 4955098 http://www.medworm.com/index.php?rid=4955097&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: We observed a higher prevalence of serological markers for HBV and a lower prevalence of anti-HCV. Our results indicate that females and patients of an advanced age are the most affected categories and that patients that received multiple transfusions are at a higher probability of HCV infection.CONTEXTO: A transfusão sanguínea destaca-se entre os fatores de risco implicados na transmissão dos vírus das hepatites B (VHB) e C (VHC); entretanto não há relatos da transmissão endoscópica destes vírus em pacientes com esquistossomose na forma hepatoesplênica. OBJETIVO: Estimar a prevalência dos marcadores sorológicos do VHB e VHC em pacientes com esquistossomose hepatoesplênica e avaliar os possíveis fatores de risco associados a essas infecções. MÉTODOS: Estudo do... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955097 Wed, 22 Jun 2011 17:46:13 +0100 4955097 http://www.medworm.com/index.php?rid=4955096&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Agreement between the data obtained from ultrasound with contrast and magnetic resonance was 94.5%. In discordant cases, the magnetic resonance diagnosis prevailed. In the case which presented indeterminate findings on contrast ultrasonography, magnetic resonance was repeated after 3 months, confirming the diagnosis of a hepatic hemangioma. A biopsy was performed on the suspected malignant nodule which also confirmed the presence of a hepatic hemangioma. Ultrasonography with contrast has the advantages of being more accessible to the public at large and lower cost than magnetic resonance. The results of our study highlight the need for a new protocol in hepatic nodules incidentally identified on conventional ultrasonography. In the case of typical hemangiomas, conventional ultr... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955096 Wed, 22 Jun 2011 17:46:13 +0100 4955096 http://www.medworm.com/index.php?rid=4955095&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Undernutrition (diminished lean body mass, risk of magnesium and vitamin deficiencies) contrasted with dyslipidemia and increased cardiovascular risk. This second danger was masked during chronic pancreatitis but not in alcoholics without visceral disease. Further studies should focus special requirements of this population.CONTEXTO: O alcoolismo pode interferir no estado nutricional, todavia, os relatos frequentemente sofrem com o viés das incertezas sobre dieta consumida, danos orgânicos subjacentes e persistência do abuso. OBJETIVO: Para identificar alterações nutricionais e de compartimentos corpóreos em alcoólatras estáveis sem variáveis de confusão clínica e dietética, foi desenhado o presente estudo piloto observacional prospectivo. Três populações bem pa... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955095 Wed, 22 Jun 2011 17:46:13 +0100 4955095 http://www.medworm.com/index.php?rid=4955094&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: H. pylori infection does not affect distal gastric cancer survival.CONTEXTO: Há evidência que a infecção por Helicobacter pylori correlacione-se com a etiologia do câncer gástrico distal. Há, entretanto, poucos estudos que analisam a sobrevivência relacionada ao H. pylori. OBJETIVO: Correlacionar a sobrevida do câncer gástrico distal com a infecção por H. pylori. MÉTODOS: Sessenta e oito pacientes com câncer gástrico distal submetidos a gastrectomia subtotal foram estudados. O tempo mínimo de seguimento foi de 1 mês. A infecção por H. pylori foi confirmada por biopsia. RESULTADOS: Trinta e quatro pacientes (19 homens (55,9%), idade média de 60,9 ± 14,03, variação 33-82 anos) tinham confirmação de infecção por H. pylori. Trinta e quatro pacientes (16 ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955094 Wed, 22 Jun 2011 17:46:13 +0100 4955094 http://www.medworm.com/index.php?rid=4955093&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200004%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Low-dose 13C-urea breath test (25 mg 13C-urea) does not reach accuracy sufficient to be recommended in clinical setting where a 30% prevalence of H. pylori infection is observed. Further studies should be done to determine the diagnostic accuracy of low doses of 13C-urea in the urea breath test.CONTEXTO: A dose convencional de 13C-ureia para a realização do teste respiratório com 13C-ureia é 75 mg. OBJETIVO: Determinar a precisão diagnóstica do teste respiratório contendo 25 mg de 13C-ureia comparada com a dose convencional de 75 mg para o diagnóstico de infecção por H. pylori. MÉTODOS: Duzentos e setenta pacientes adultos (96 homens, 174 mulheres, idade mediana de 41 anos) realizaram o teste respiratório convencional (75 mg 13C-ureia) e repetiram o teste respiratÃ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955093 Wed, 22 Jun 2011 17:46:13 +0100 4955093 http://www.medworm.com/index.php?rid=4955092&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Gastroesophageal reflux disease is a chronic disease in which gastroduodenal contents reflux into the esophagus. The clinical picture of gastroesophageal reflux disease is usually composed by heartburn and regurgitation (typical manifestations). Atypical manifestations (vocal disturbances and asthma) may also be complaint. OBJECTIVE: To analyse the clinical, endoscopic, manometric and pHmetric aspects of patients suffering from gastroesophageal reflux disease associated with vocal disturbances. METHODS: Fifty patients with gastroesophageal reflux disease were studied, including 25 with vocal disturbances (group 1 - G1) and 25 without these symptoms (group 2 - G2). All patients were submitted to endoscopy, manometry and esophageal pHmetry (2 probes). The group 1 patients were submi... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955092 Wed, 22 Jun 2011 17:46:13 +0100 4955092 http://www.medworm.com/index.php?rid=4955091&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200002%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Gastroesophageal reflux disease (GERD) is common in patients with respiratory disorders and interstitial lung fibrosis from diverse disease processes. However, a cause-effect relationship has not been well demonstrated. It is hypothesized that there might be more than a coincidental association between GERD and interstitial lung damage. There is still confusion about the diagnostic steps necessary to confirm the presence of GERD, and about the role of effective control of GERD in the natural history of these respiratory disorders. OBJECTIVES: To determine the prevalence of GERD in patients with respiratory disorders and lung involvement; the sensitivity of symptoms in the diagnosis of GERD; and the role of esophageal function tests (manometry and 24- hour pH monitoring) in the dia... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955091 Wed, 22 Jun 2011 17:46:13 +0100 4955091 http://www.medworm.com/index.php?rid=4955090&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000200001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4955090 Wed, 22 Jun 2011 17:46:13 +0100 4955090 http://www.medworm.com/index.php?rid=4768853&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100017%26lng%3Den%26nrm%3Diso%26tlng%3Den The objective of this paper is to correlate the maximal oxygen uptake (VO2max) and respiratory muscle strength and evaluating the quality of life in liver transplant candidates. Cross-sectional study consisted of 26 patients with cirrhosis who underwent maximal exercise testing, respiratory muscle strength and SF-36. There was a correlation of VO2max with MIP (r = 0.61) and low scores of quality of life. A correlation of VO2max to muscle strength and decreased quality of life in patients with liver disease.As doenças hepáticas são responsáveis pelas alterações metabólicas e cardiorrespiratórias. O objetivo deste estudo foi correlacionar o consumo máximo de oxigênio (VO2max) com a força muscular respiratória e avaliar a qualidade de vida em candidatos ao transplante de fígado. ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768853 Sun, 01 May 2011 14:35:00 +0100 4768853 http://www.medworm.com/index.php?rid=4768852&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100016%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Methotrexate-induced intestinal mucositis delays gastric emptying and gastrointestinal transit of liquids in awake rats.CONTEXTO: Metotrexato e outros agentes anticâncer podem induzir uma mucosite intestinal, que é um dos fatores de limitante mais comum que limitam o aumento escalonado da dose do metotrexato. OBJETIVOS: Avaliar o esvaziamento gástrico e o trânsito gastrointestinal de líquidos na mucosite intestinal induzida por metotrexato. MÉTODOS: Ratos Wistar, receberam metotrexato (2.5 mg/kg/dia por 3 dias, subcutâneo) ou salina. Após 1, 3 ou 7 dias, secções do duodeno, jejuno e íleo foram retirados para análise morfométrica e dosagem da atividade de mieloperoxidase (marcador bioquímico da infiltração de neutrófilos). Outros ratos foram pré-tratados com me... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768852 Sun, 01 May 2011 14:35:00 +0100 4768852 http://www.medworm.com/index.php?rid=4768851&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100015%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The low cost and easily accessible methionine- and choline-deficient diet explored in this study is highly effective in inducing steatosis and steatohepatitis in animal model, alterations that are similar to those observed in human livers.CONTEXTO: A esteatohepatite não-alcoólica é uma doença com alta incidência, difícil diagnóstico e tratamentos ainda não efetivos. Com isso, o uso de modelos experimentais para indução da esteatohepatite não-alcoólica e o estudo das rotas de desenvolvimento desta doença vem sendo empregado. OBJETIVO: Desenvolver um modelo experimental de esteatohepatite não-alcoólica a partir do uso de uma dieta deficiente de metionina e colina fabricada no Brasil e avaliar as alterações hepáticas decorrentes da doença. MÉTODO: Foram utiliza... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768851 Sun, 01 May 2011 14:35:00 +0100 4768851 http://www.medworm.com/index.php?rid=4768850&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100014%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Peripheral neuropathy is one of the chronic complications of diabetes mellitus and is directly related to gastrointestinal consequences of the disease. Myenteric neurons are affected in some pathological conditions such as diabetic neuropathy. The imbalance between cellular antioxidants and free radicals, leading to an increase in oxidative stress, is considered one of the main factors responsible for neuronal damages in diabetes. Drugs that reduce the oxidative stress may play a significant role in the treatment of neurological complications of diabetes mellitus. OBJECTIVE: To evaluate the effect of L-glutamine supplementation on the myenteric neurons from the cecum and duodenum of Wistar rats with streptozotocin-induced diabetes mellitus. METHODS: The animals were divided in fou... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768850 Sun, 01 May 2011 14:35:00 +0100 4768850 http://www.medworm.com/index.php?rid=4768849&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION:The evaluation of the nutritional status showed that eutrophy is prevalent in patients, and they presented a higher body fat value than the control group, with a significant difference. More research is needed with adolescents with autoimmune hepatitis regarding levels of essential micronutrients, such as zinc, because a good nutritional status can improve the prognostic of liver disease.CONTEXTO: A deficiência de zinco em crianças ou adolescentes acarreta danos ao crescimento, desenvolvimento e ao sistema imune dos indivíduos. OBJETIVO: Verificar a existência de deficiência de zinco plasmático e/ou leucocitário em adolescentes com hepatite autoimune. MÉTODOS:Participaram do estudo 23 pacientes com hepatite autoimune entre 10 e 18 anos, atendidos no Ambulatório de Hepat... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768849 Sun, 01 May 2011 14:35:00 +0100 4768849 http://www.medworm.com/index.php?rid=4768848&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Malnutrition is frequently observed in inpatients with malignant diseases and may contribute to longer hospital stays. OBJECTIVE: To compare the nutritional status, lymphocyte count, hemoglobin values and length of hospital stay of patients with and without malignant diseases. METHODS: This comparative study assessed indicators of nutritional status, namely body mass index, recent weight loss, lymphocyte count, hemoglobin and length of hospital stay, of 928 surgical patients with and without malignant diseases (50.2% females and 49.8% males). The chi-square test was used to compare proportions and the Mann-Whitney test was used to compare continuous measurements between two groups. The significance level was set at 5%. RESULTS: Patients with malignant diseases had longer hospital ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768848 Sun, 01 May 2011 14:35:00 +0100 4768848 http://www.medworm.com/index.php?rid=4768847&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: The treatment of Chagas' disease colopathy is limited to clinical management in the initial of the process, and for patients for whom surgery is not indicated or is not possible, anti-constipation diets are used, along with judicious administration of laxatives and enemas. OBJECTIVE: To evaluate over time the effects of physical-therapy interventions combined with daily ingestion of a laxative fruit drink in the treatment of chagasic megacolon. METHOD: In a quantitative, prospective, and comparative study, 12 patients of both sexes and with a mean age of 67 ± 12 years were clinically evaluated to receive 12 sessions of physical therapy twice a week, along with fruit drink, and were evaluated for intestinal constipation before and after treatment. RESULTS: A significant difference... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768847 Sun, 01 May 2011 14:35:00 +0100 4768847 http://www.medworm.com/index.php?rid=4768846&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Our results demonstrate that the interaction between polymorphism in the interleukin -8 (-251) gene, particularly with carriers of the A allele and the infecting type of H. pylori strain (s1m1 cagA positive) performs an important function in development of gastric adenocarcinoma.CONTEXTO: A neoplasia gástrica é a segunda causa mais comum de morte por câncer no mundo e o H. pylori é classificado como carcinógeno humano tipo I pela Organização Mundial de Saúde. Entretanto, apesar da elevada prevalência da infecção pelo H. pylori em todo mundo, menos de 3% de indivíduos portadores dessa bactéria desenvolvem neoplasias gástricas. Tal fato indica que a evolução para malignização possa estar associada a fatores bacterianos, do hospedeiro e do ambiente. OBJETIVOS: In... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768846 Sun, 01 May 2011 14:35:00 +0100 4768846 http://www.medworm.com/index.php?rid=4768845&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: There is an association between cagA-positive H. pylori strain and risk of gastric cancer.CONTEXTO: O câncer gástrico é a segunda causa mais comum de mortes relacionadas à neoplasia em todo o mundo. Embora o Helicobacter pylori seja classificado como um carcinógeno classe I, a presença da infecção não é um fator que isoladamente possa conduzir ao câncer gástrico e, uma das possíveis justificativas, é a existência de diferentes linhagens de H. pylori com diferentes graus de virulência. OBJETIVO: Investigar a associação entre H. pylori cagA-positivo e câncer gástrico, utilizando a reação em cadeia de polimerase (PCR) para a detecção desta linhagem bacteriana. MÉTODOS: Vinte e nove pacientes com câncer gástrico foram pareados por sexo e por idade (± 5 ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768845 Sun, 01 May 2011 14:35:00 +0100 4768845 http://www.medworm.com/index.php?rid=4768844&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Recent studies support the hypothesis that postinfectious irritable bowel syndrome and some irritable bowel syndrome patients display persistent signs of minor mucosal inflammation. Mesalazine has intestinal anti-inflammatory properties including cyclooxygenase and prostaglandin inhibition. The effects of mesalazine on postinfectious irritable bowel syndrome and noninfective irritable bowel syndrome patients are still unknown. OBJECTIVE: To observe the effects of mesalazine on postinfectious irritable bowel syndrome and noninfective irritable bowel syndrome with diarrhea patients. METHODS: Based on Rome III criteria, 61 irritable bowel syndrome with diarrhea patients (18 years old or more) were included in the evaluation. Patients were divided into two groups: postinfectious irrit... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768844 Sun, 01 May 2011 14:35:00 +0100 4768844 http://www.medworm.com/index.php?rid=4768843&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The effort of evacuation associated with postexpiratory apnea, when compared with the effort associated with the Valsalva maneuver, provides lower elevation of anal pressure at rest by the parameter area under the curve.CONTEXTO: A constipação intestinal é um sintoma comum na população, sendo mais frequente em mulheres, podendo ser secundária a erro alimentar, distúrbios orgânicos ou funcionais. Dentre estes, destaca-se a discinesia do assoalho pélvico, caracterizada basicamente por ausência de relaxamento ou contração paradoxal da musculatura pélvica e do canal anal no momento da evacuação. O melhor conhecimento dos mecanismos envolvidos na constipação de etiologia funcional pode contribuir em terapêuticas mais eficazes. OBJETIVO: Analisar através de dados m... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768843 Sun, 01 May 2011 14:35:00 +0100 4768843 http://www.medworm.com/index.php?rid=4768842&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Esophageal pH monitoring with wireless capsule is safe, well tolerated, does not require sedation. The extended 48-h period of study poses an increased yield to diagnose gastroesophageal reflux disease patients.CONTEXTO: A doença do refluxo gastroesofágico é uma das doenças digestivas mais comuns e importante causa de desconforto para os pacientes. O diagnóstico desta condição clínica pode requerer monitoramento ambulatorial do pH esofágico. OBJETIVOS: Determinar o espectro diagnóstico do sistema de monitoramento ambulatorial do pH esofágico com cápsula telemétrica por um período de 48 horas no diagnóstico da variabilidade diária da exposição ácida anormal e sua associação com sintomas. MÉTODOS: Foram incluídos 100 pacientes adultos, consecutivos, com sin... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768842 Sun, 01 May 2011 14:35:00 +0100 4768842 http://www.medworm.com/index.php?rid=4768841&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Achalasia is a primary esophageal motor disorder secondary to the degeneration of ganglion cells of the inhibitory intramural myenteric plexus. It affects both sexes similarly and has two peaks of incidence, one in the 3rd to 4th decades of life and the other after 60 years of age. The effect of age on esophageal motility of patients with achalasia is not well known. Studies have shown that healthy older people, when compared to the young, have: a) a lower number of ganglion cells in the intramural myenteric plexus; b) a reduced normal relaxation of the lower esophageal sphincter; and c) a reduced esophageal peristalsis. Thus, as both age and achalasia can produce comparable degenerative changes in the intramural myenteric plexus, it is possible that advanced age could be an impor... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768841 Sun, 01 May 2011 14:35:00 +0100 4768841 http://www.medworm.com/index.php?rid=4768840&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100004%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Bariatric surgery may cause more intense alterations of liquid bolus swallowing within 2 months after the procedure, which moved to normal values after this time.CONTEXTO: Cirurgia bariátrica é tratamento efetivo para a obesidade. Após a operação o paciente pode ter dificuldade em ingerir alimentos líquidos e sólidos. OBJETIVO: Avaliar a ingestão de líquido em pacientes submetidos a cirurgia bariátrica. MÉTODOS: Estudaram-se 43 voluntários com índice de massa corporal (IMC) normal (18,9 - 24,5 kg/m²), 55 sujeitos com obesidade classe III (IMC: >40.6 kg/m²), e 48 sujeitos que haviam sido submetidos a cirurgia bariátrica para tratamento de obesidade classe III. Utilizou-se na avaliação o teste de deglutição de água. Os sujeitos ingeriram 50 mL de água enquan... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768840 Sun, 01 May 2011 14:35:00 +0100 4768840 http://www.medworm.com/index.php?rid=4768839&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: A Recife Score >3 prior to conventional gastric bypass presents a high level of accuracy in the prediction of serious postoperative complications and death.CONTEXTO: Pacientes superobesos submetidos a gastroplastia apresentam maior incidência de complicações. Alto risco cirúrgico decorre da maior incidência de comorbidades nesse grupo, levando à necessidade de cuidados especiais. Analisando os fatores de risco identificados no pré-operatório, pontuando-os, construindo um escore e avaliando a ocorrência de complicações graves e óbito, serão fornecidos elementos para identificar quais os pacientes de maior risco. OBJETIVO: Determinar a precisão do Escore de Recife para predição de complicações pós-operatórias graves e óbito em pacientes superobesos submetidos... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768839 Sun, 01 May 2011 14:35:00 +0100 4768839 http://www.medworm.com/index.php?rid=4768838&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100002%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Since anorectocele is usually associated with mucosa prolapse and/or rectal intussusceptions, it was developed a stapled surgical technique using one circular stapler. OBJECTIVE: To report the results of Transanal Repair of Rectocele and Rectal Mucosectomy with one Circular Stapler (TRREMS procedure) in the treatment of anorectocele with mucosa prolapse in a prospective multicenter trial. METHODS: It was conducted by 14 surgeons and included 75 female patients, mean aged 49.6 years, with symptoms of obstructed defecation due to grade 2 (26.7%) and grade 3 (73.3%) anorectocele associated with mucosa prolapse and/or rectal intussusception (52.0%) and an average validated Wexner constipation score of 16. All patients were evaluated by a proctological examination, cinedefecography, an... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768838 Sun, 01 May 2011 14:35:00 +0100 4768838 http://www.medworm.com/index.php?rid=4768837&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032011000100001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4768837 Sun, 01 May 2011 14:35:00 +0100 4768837 http://www.medworm.com/index.php?rid=4323119&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400014%26lng%3Den%26nrm%3Diso%26tlng%3Den Mirazid® is a patented preparation from a plant that had been used in folk medicine since ancient Egyptians (Myrrh). It was registered in Egypt for the treatment of schistosomiasis and fascioliasis. Over 32 independent studies for efficacy of Mirazid had been reviewed and their results analyzed. The majority of these studies reported higher than 90% cure rates, that even higher in mixed than single trematodal infections in humans and in farm animals. Only two groups of investigators reported lower cure rates as they used lower doses and estimated cure rates at a shorter period from treatment than recommended by innovators.Mirazid® é um produto patenteado preparado a partir de planta usada na medicina popular desde o Egito antigo conhecida como Mirra. Está registrada no Egito para o tra... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323119 Sat, 08 Jan 2011 12:16:52 +0100 4323119 http://www.medworm.com/index.php?rid=4323118&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The hyperglucidic diet induced hepatic steatosis. In the heart there was an increase in fat content, although no histological changes were observed. These alterations cannot be explained by the presence of malondialdehyde or reduced glutathione (indicators of oxidation), since the values were similar in the groups studied. However, a significant reduction of vitamin E was observed in the experimental group.CONTEXTO: O padrão alimentar ocidental é caracterizado pela ingestão de dieta rica em açúcares simples. Esta alimentação é associada com comorbidades como, por exemplo, deposição de gordura no fígado e possivelmente relacionada com a esteatose hepática não-alcoólica. OBJETIVO: Avaliar a capacidade de uma alimentação hiperglicídica induzir esteatose em ratos W... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323118 Sat, 08 Jan 2011 12:16:52 +0100 4323118 http://www.medworm.com/index.php?rid=4323117&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The global index of surgical site infections and its incidence among contaminated procedures are within the expected limits. On the other hand according to SIRI, the surgical site infection indexes are above the expected standards both for the clean and for the contaminated procedures.CONTEXTO: As infecções do sítio cirúrgico constituem risco inerente ao ato operatório, principalmente após cirurgias digestivas. Ocorrem até 30 dias após a cirurgia, ou até 1 ano, se houver implante de prótese. O índice de risco de infecção cirúrgica (IRIC), metodologia NISS (National Nosocomial Infection Surveillance), é um método de avaliação do risco de infecções do sítio cirúrgico que considera o potencial de contaminação da cirurgia, o estado de saúde do paciente e o ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323117 Sat, 08 Jan 2011 12:16:52 +0100 4323117 http://www.medworm.com/index.php?rid=4323116&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: In Recife, the prevalence of primary clarithromycin resistance, 16.5%, showed the need for pretreatment susceptibility testing in H. pylori infections.CONTEXTO: Claritromicina é a droga mais eficaz usada na erradicação da infecção pelo H. pylori. Devido ao aumento mundial da resistência, o teste de susceptibilidade à claritromicina pré-tratamento é recomendado. OBJETIVO: Determinar a prevalência de H. pyloriclaritromicina resistente em Recife, PE, Brasil. MÉTODO: De janeiro de 2006 a dezembro de 2007, 114 biopsias gástricas positivas à cultura para H. pylori foram diretamente analisadas pela reação em cadeia da polimerase (PCR), para detectar a frequência das mutações em ponto que envolvem a resistência à claritromicina. Os resultados foram comparados com os... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323116 Sat, 08 Jan 2011 12:16:52 +0100 4323116 http://www.medworm.com/index.php?rid=4323115&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Desmoid tumors were found in 13.2% of cases of familial adenomatous polyposis following colectomy; therefore, familial adenomatous polyposis patients should be followed-up and surveillance should include abdominal examination to detect signs and symptoms. Treatment options include surgery and clinical management with antiestrogens, antiinflammatory drugs or chemotherapy.CONTEXTO: Os tumores desmóides representam uma das manifestações extraintestinais mais importantes na síndrome da polipose adenomatosa familiar. O aparecimento desta neoplasia está relacionada ao aumento da morbimortalidade nos doentes com polipose adenomatosa familiar. OBJETIVOS: Avaliar a ocorrência dos tumores desmóides nos casos de polipose adenomatosa familiar submetidos a colectomia profilática e ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323115 Sat, 08 Jan 2011 12:16:52 +0100 4323115 http://www.medworm.com/index.php?rid=4323114&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Two-dimensional dynamic anal ultrasonography showed similar results previously suggested by anal manometry at identifying patients with normal relaxation or paradoxical contraction.CONTEXTO: O anismus é uma causa funcional frequente de evacuação obstruída. Caracteriza-se por sintomas de evacuação obstruída associada à presença de contração paradoxal dos músculos do assoalho pélvico. OBJETIVO: Avaliar o papel do ultrassom anorretal bidimensional dinâmico em identificar pacientes com contração paradoxal (anismus) ou relaxamento normal, comparando os resultado com medidas manométricas. MÉTODOS: Quarenta e nove mulheres com evacuação obstruída e com média de escore de constipação de 13.5 foram incluídas neste estudo prospectivo. Os pacientes foram divididos... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323114 Sat, 08 Jan 2011 12:16:52 +0100 4323114 http://www.medworm.com/index.php?rid=4323113&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: NM23, a metastasis suppressor gene, may be associated with prognosis in patients with colorectal carcinoma. OBJECTIVE: To analyze NM23 expression and its association with the presence of lymph node and liver metastases and survival in patients operated on for colorectal carcinoma. METHODS: One hundred thirty patients operated on for colorectal carcinoma were investigated. Tissue microarray blocks containing neoplastic tissue and tumor-adjacent non-neoplastic mucosa were obtained and analyzed by immunohistochemical staining using a monoclonal anti-NM23 antibody. Immunohistochemical expression was assessed using a semiquantitative scoring method, counting the percentage of stained cells. The results were compared regarding morphological and histological characteristics of the colore... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323113 Sat, 08 Jan 2011 12:16:52 +0100 4323113 http://www.medworm.com/index.php?rid=4323112&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Validated questionnaires are essential tools to be utilized in epidemiological research. At the moment there are no Rome III diagnostic questionnaires translated to Portuguese. OBJECTIVE: To validate the Portuguese version of the Rome III Diagnostic Questionnaire for Functional Dyspepsia. METHODS: The questionnaire has been translated following the Rome III recommendations. Hundred and nine consecutive patients with functional dyspepsia answered the questionnaire. The control group comprised 100 healthy consecutive blood donors, without digestive problems. Internal consistency, reproducibility, responsiveness, discriminate validity and content analysis were evaluated. RESULTS: Cronbach's α coefficient was 0.92. The questionnaire showed reliability: the patients answered it in a s... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323112 Sat, 08 Jan 2011 12:16:52 +0100 4323112 http://www.medworm.com/index.php?rid=4323111&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Undernutrition is a well known underlying cause in both disease onset and outcome. OBJECTIVE: To associate disease severity with pre surgical nutritional status, the main postsurgical complications, and mortality in esophagus cancer patients. METHOD: Retrospective data from 100 patients (38-81 years old, 85% males) who had undergone esophagectomy (G1/n = 25) or gastro/jejunostomy (G2/n = 75) between 1995 and 2004. Data included clinical, endoscopic, histological (TNM-UICC), dietary, anthropometric, blood chemistry, and postsurgical (>30 days) complications and mortality. Surgical groups were compared by Student's test and existing associations between variables by either c² or Fisher exact tests with P = 0.05. RESULTS: The studied sample was predominantly male (85%), white (80... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323111 Sat, 08 Jan 2011 12:16:52 +0100 4323111 http://www.medworm.com/index.php?rid=4323110&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: In a previously published study, the variables lower rectal tumor site, preoperative chemoradiotherapy and large tumors were considered as independent risk factors for the inability of sentinel lymph node identification in patients with colorectal adenocarcinoma. OBJECTIVES: To determine if these variables could interfere in the precision and upstaging benefit of sentinel lymph node mapping in colorectal cancer. METHODS: A database composed of 52 patients submitted to lymphatic mapping using technetium-99m-phytate and patent blue was reviewed. Only patients with tumors smaller than 5.0 cm, not submitted to preoperative chemoradiotherapy and without lower rectal cancer were included. RESULTS: With these parameters, 11 patients remained to be studied. The sentinel lymph node identif... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323110 Sat, 08 Jan 2011 12:16:52 +0100 4323110 http://www.medworm.com/index.php?rid=4323109&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400004%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: It has been demonstrated that the ageing process affects esophageal motility. OBJECTIVES: To evaluate the effect of the age on the proximal esophageal response to wet swallows. METHOD: We measured the proximal esophageal response to swallows of a 5 mL bolus of water in 69 healthy volunteers, 20 of them aged 18-30 years (group I), 27 aged 31-50 years (group II), and 22 aged 51-74 years (group III). We used the manometric method with continuous perfusion. The proximal esophageal contractions were recorded 5 cm from a pharyngeal recording site located 1 cm above the upper esophageal sphincter. The time between the onset of the pharyngeal and of the proximal esophageal recording (pharyngeal-esophageal time) and the amplitude, duration and area under the curve of the proximal esophagea... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323109 Sat, 08 Jan 2011 12:16:52 +0100 4323109 http://www.medworm.com/index.php?rid=4323108&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Oropharyngeal dysphagia is part of the Machado-Joseph disease since the first neurological manifestations. There is greater involvement of the pharyngeal phase, in relation to oral phase of the deglutition. The dysphagia of these patients is classified between mild and moderate.CONTEXTO: Na doença de Machado-Joseph, a má postura, a distonia e a neuropatia periférica predispõem à disfagia orofaríngea, mais comumente associada à distrofia muscular. OBJETIVO: Avaliar as características clínicas da disfagia orofaríngea em pacientes com doença de Machado-Joseph. MÉTODOS: Quarenta indivíduos participaram do estudo, incluindo 20 sem quaisquer queixas clínicas e 20 disfágicos com doença de Machado-Joseph do tipo clínico 1, grupos similares em termos de sexo, média de... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323108 Sat, 08 Jan 2011 12:16:52 +0100 4323108 http://www.medworm.com/index.php?rid=4323107&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400002%26lng%3Den%26nrm%3Diso%26tlng%3Den O advento de novas tecnologias na saúde causou impacto nos indicadores clínicos e econômicos. Os métodos de pesquisa que incorporam conceitos da economia da saúde e epidemiologia clínica permitem avaliar a eficiência de novas tecnologias, por exemplo, através da análise de custo-efetividade. Este é um instrumento de análise de valor das intervenções em saúde. A metodologia, análise de custo-efetividade, é condição determinante da moderna prática de cuidados à saúde, pois as opções terapêuticas hoje disponíveis no Sistema Único de Saúde (SUS) ou no sistema de saúde suplementar do Brasil passam necessariamente por tal análise, logo o sistema de saúde bem como os profissionais da saúde são levados a reexaminar os benefícios e custos de suas ações para assegu... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323107 Sat, 08 Jan 2011 12:16:52 +0100 4323107 http://www.medworm.com/index.php?rid=4323106&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000400001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4323106 Sat, 08 Jan 2011 12:16:52 +0100 4323106 http://www.medworm.com/index.php?rid=4250055&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300002%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Considering the particularities of the endoscope and its reprocessing, it is imperative to establish protocols to ensure the quality of the disinfection and the prevention of cross-contamination.CONTEXTO: A segurança do procedimento endoscópico depende do uso de um aparelho adequadamente reprocessado e a qualidade do reprocessamento está relacionada a cada uma das etapas operacionais desse processo. OBJETIVO: Caracterizar o reprocessamento de endoscópios pelo uso do glutaraldeído em serviços de endoscopia. MÉTODOS: Estudo conduzido em 20 serviços de endoscopia digestiva do município de Goiânia, GO. A amostra se constituiu de endoscópios utilizados para endoscopia digestiva alta. Os dados foram obtidos mediante observação direta de 60 reprocessamentos de endoscópio... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4250055 Sat, 11 Dec 2010 16:59:35 +0100 4250055 http://www.medworm.com/index.php?rid=4234517&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300019%26lng%3Den%26nrm%3Diso%26tlng%3Den This is the first Brazilian Consensus on inflammatory bowel disease, carried out by the Brazilian Study Group of Inflammatory Bowel Disease, and discusses the treatment of Crohn's disease and ulcerative colitis in acute and remission phases. The first part of the text, brings out a review on the main drugs used in the treatment of inflammatory bowel disease, as well as their mechanisms of action and cautions during their use. In the second part, the committee's opinions about the most recommended medical and surgical approaches for both diseases are presented on the basis of disease activity, location and behaviour status. The recommendations here presented were widely discussed in several scientific meetings with active participation of all members of the group and were highly based on sc... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234517 Tue, 07 Dec 2010 16:20:51 +0100 4234517 http://www.medworm.com/index.php?rid=4234516&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300018%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Pathogenesis of persistent diarrhea should include alterations in the small bowel structures where the digestive-absorptive functions take place. In the colonic mucosa the inflammatory lesions could explain the occurrence of colitis.CONTEXTO: A Escherichia coli enteroagregativa está associada à diarréia persistente em vários países em desenvolvimento. Procedimentos in vivo empregando modelos animais como ratos, coelhos e alças intestinais de suínos gnotobióticos, e modelos in vitro com linhas celulares, tais como: T84, Caco 2, HT29, HeLa e HEp-2 e cultura de órgão in vitro são empregados no estudo desta bactéria e de sua patogenicidade. OBJETIVOS: Neste trabalho foram avaliadas as interações de três cepas de Escherichia coli enteroagregativa usando cultura de ó... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234516 Tue, 07 Dec 2010 16:20:51 +0100 4234516 http://www.medworm.com/index.php?rid=4234515&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300017%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: In this study Croton cajucara bark extract showed absence of hepatotoxicity in this animal model and presented a hypolipidemic activity, and could be used to reverse dyslipidemia associated with diabetes and to prevent the cardiovascular complications that are very prevalent in diabetic patients.CONTEXTO: Croton cajucara Benth é uma planta encontrada na Amazônia, Brasil. Infusões da casca e folhas desta planta são utilizadas popularmente no tratamento de diabetes e doenças hepáticas. OBJETIVOS: Este estudo investigou as alterações hepáticas e os efeitos genotóxicos da casca do extrato do Croton cajucara Benth em animais diabéticos induzidos por estreptozotocina. MÉTODOS: Ratos Wistar machos foram divididos em seis grupos: ratos controle, ratos controle tratados com ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234515 Tue, 07 Dec 2010 16:20:51 +0100 4234515 http://www.medworm.com/index.php?rid=4234514&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300016%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: There are consistent clues of worse results with grafts from older donors, especially in hepatitis C. University of Wisconsin (UW) solution is adopted for liver preservation, but other solutions are being studied, as fructose-1,6-bisphosphate (FBP). OBJECTIVE: To determinate the impact of aging of the donor on the cold ischemia injury in rat livers and compare UW and FBP. METHODS: Twenty male Wistar rats were studied - 10, aging 20 weeks: 5 to preservation with UW (C-UW) and 5, FBP (C-FBP); and other 10, aging 50 weeks: 5 to UW (E-UW) and 5 to FBP (E-FBP). Rats were anesthesized, submitted to hepatectomy, and graft was kept under 2-4ºC for 8 hours. Liquid samples were taken at 2, 4, 6, and 8 hours, to determine AST and LDH. At the end, in the liver tissue thiobarbituric acid reac... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234514 Tue, 07 Dec 2010 16:20:51 +0100 4234514 http://www.medworm.com/index.php?rid=4234513&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300015%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Gamma-aminobutyric acid (GABA) is a potent inhibitory neurotransmitter. There is evidence that GABA B receptors located in the dorsal complex and in afferent fibers of the vagus nerve participate in the control of gastrointestinal motility. OBJECTIVE: To assess the intracerebroventricularly (ICV) and intravenously (IV) effect of baclofen, a GABA B receptor agonist, on liquid and solid gastric emptying in rats. METHODS: Adult male Wistar rats weighing 250-300 g (n = 6-8 animals) were used. Gastric emptying of liquid test meals labeled with phenol red was evaluated by the determination of percent gastric retention (%GR) 10 and 15 min after orogastric administration of saline and 10% glucose meals, respectively. Baclofen was injected ICV (1 and 2 µg/animal) through a tube implanted ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234513 Tue, 07 Dec 2010 16:20:51 +0100 4234513 http://www.medworm.com/index.php?rid=4234512&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300014%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: It was noticed that the quality of life of patients with inflammatory bowel disease did not differ among patients with Crohn's disease or ulcerative colitis, when patients are in remission. The main aspect which determines the loss of quality of life would be being at the stage of disease activity.CONTEXTO: As doenças inflamatórias intestinais são doenças crônicas e, com isso, podem exercer impacto sobre a qualidade de vida do indivíduo. OBJETIVO: Avaliar a qualidade de vida de adultos com doenças inflamatórias intestinais, através do Inflammatory Bowel Disease Questionnaire -validado para a língua portuguesa, e comparar esta resposta entre pacientes com a doença em atividade ou não. MÉTODOS: Foram entrevistados 50 indivíduos de ambos os sexos, com idade entre 18 ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234512 Tue, 07 Dec 2010 16:20:51 +0100 4234512 http://www.medworm.com/index.php?rid=4234511&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Crohn's disease presents very heterogeneous features from a clinical point of view, and classifying Crohn's disease patients in homogeneous subgroups in the light of genetic, molecular and clinical aspects is challenging. The Montreal Classification for Crohn's disease was proposed in 2005 as an effort to characterize Crohn's disease patients according to recent clinical and research advances in the field of inflammatory bowel disease. Since its proposition, the Montreal Classification needs an ample validation and application among different populations around the world. To date, there are no known studies applying the Montreal Classification to a Brazilian cohort of Crohn's disease patients. OBJECTIVES: To apply the Montreal Classification to a Brazilian cohort of Crohn's diseas... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234511 Tue, 07 Dec 2010 16:20:51 +0100 4234511 http://www.medworm.com/index.php?rid=4234510&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Upper gastrointestinal bleeding associated to esophageal varices is the most dramatic complication of cirrhosis. It is recommended screening every cirrhotic for esophageal varices with endoscopy. OBJECTIVES: To evaluate the capacity of the platelet count/spleen diameter ratio in non-invasively predicting esophageal varices in a population of cirrhotics originated in an independent center from the one in which it was developed. METHODS: The study included patients from the ambulatory care clinic of cirrhosis of a Brazilian hospital and studied platelet count, spleen diameter and presence of esophageal varices, as well as Child and MELD scores. It used a cutoff value of 909 for the platelet count/spleen diameter ratio, as previously published. A sample of 139 patients was needed to ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234510 Tue, 07 Dec 2010 16:20:51 +0100 4234510 http://www.medworm.com/index.php?rid=4234509&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Local anesthesia plus sedation offers a safer and more effective method than spinal anesthesia for loop colostomy closure.CONTEXTO: Estudos recentes têm demonstrado que a anestesia local para o fechamento de colostomia em alça é tão segura quanto a raquianestesia para estes procedimentos. OBJETIVOS: Comparar os resultados do fechamento de colostomia em alça usando essas duas técnicas. MÉTODOS: Cinquenta pacientes foram randomizados para o fechamento de colostomia em alça sob raquianestesia (n = 25) e anestesia local (n = 25). No pré-operatório, o cólon foi avaliado por colonoscopia e o preparo intestinal foi realizado com solução oral de manitol a 10% e limpeza com solução salina fisiológica através do orifício distal da colostomia. Todos os pacientes receber... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234509 Tue, 07 Dec 2010 16:20:51 +0100 4234509 http://www.medworm.com/index.php?rid=4234508&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: The surgical treatment for morbid obesity is becoming common in this country. Only a few papers reported the long-term results of the surgical approach for morbid obesity, mainly in terms of quality of life. OBJECTIVE: To compare mortality rate, weight loss, improvement of both diabetes and hypertension, and quality of life of patients from the public healthcare in Cuiabá, MT, Brazil, who underwent either medical or surgical interventions after a minimum of 2 years. METHODS: The population of this study was constituted by morbidly obese patients who initiated treatment between June 2002 and December 2006. The casuistic consisted of 89 patients submitted to medical therapy and 76 patients who underwent surgical procedures. The main variables were weight loss, improvement of hypert... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234508 Tue, 07 Dec 2010 16:20:51 +0100 4234508 http://www.medworm.com/index.php?rid=4234507&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Considering the cost-benefit of the HLA typing of all the first degree relatives of celiac patients, their HLA status should be decided on an individual basis, taking account of their profile and preferences, and the existence of other medical conditions.CONTEXTO: A susceptibilidade para a doença celíaca está principalmente associada à presença dos alelos HLA DQA1*0501 e DQB1*0201 (que conjuntamente codificam o heterodímero DQ2), os quais são praticamente encontrados em todos os pacientes celíacos. O heterodímero DQ8 (codificado pelos alelos DQA1*03 e DQB1*0302) associado ao haplotipo DRB1*04 (DR4) é comumente encontrado nos pouco pacientes celíacos que não carregam o heterodímero DQ2. OBJETIVOS: Determinar a prevalência de doença celíaca em grupo de parentes d... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234507 Tue, 07 Dec 2010 16:20:51 +0100 4234507 http://www.medworm.com/index.php?rid=4234506&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Positive AGAA, AGAG or EmA results are probably nonspecific for the presence of celiac disease among autoimmune rheumatologic disease patients. The intake of prednisone and immunosuprressant drugs seems to reduce the prevalence of IgA EmA, but it does not interfere with antigliadin antibodies tests.Further studies are required to estimate more accurately the prevalence of this disease in rheumatologic patients.CONTEXTO: Tanto os pacientes com doenças reumatológicas autoimunes quanto os com doença celíaca costumam apresentar vários tipos de autoanticorpos, muitos deles ainda sem papel definido na etiopatogênese dessas afecções. Apesar de tratar-se de assunto controverso, é bastante citada na literatura a maior prevalência da doença celíaca em diversos grupos de paci... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234506 Tue, 07 Dec 2010 16:20:51 +0100 4234506 http://www.medworm.com/index.php?rid=4234505&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The 3.6% prevalence of biopsy-proven CD among this group of females with Turner syndrome is 10 times higher than the one among females from the general population of the same geographical area. This result provides additional support to an association between these two disorders and restates that girls and women with Turner syndrome represent a high risk population for developing CD.CONTEXTO: Alguns estudos têm demonstrado maior prevalência de doença celíaca entre mulheres com síndrome de Turner, quando comparadas com a população geral. Entretanto, não há registro na literatura desta investigação em pacientes brasileiras. OBJETIVO: Avaliar a prevalência de doença celíaca entre um grupo de pacientes brasileiras com síndrome de Turner. MÉTODOS: Cinquenta e seis pa... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234505 Tue, 07 Dec 2010 16:20:51 +0100 4234505 http://www.medworm.com/index.php?rid=4234504&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The detection of ASCA in patients with celiac disease allows to suggest that ASCA is not a specific marker for Crohn's disease, but was associated with the inflammation of the small intestine. The increased levels of positive ASCA may be due to genetic factors and increased intestinal permeability.RACIONAL: Anticorpos anti-Saccharomyces cerevisiae antibodies, considerados marcadores sorológicos para a doença de Crohn, foram descritos em pacientes com doença celíaca, desaparecendo após dieta isenta de glúten. OBJETIVOS: Avaliação da positividade de anti-Saccharomyces cerevisiae antibodies em pacientes com doença de Crohn e doença celíaca, em relação a indivíduos sadios da mesma área geográfica. MÉTODOS: Foram estudados 145 pacientes, 36 com doença de Crohn e 5... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234504 Tue, 07 Dec 2010 16:20:51 +0100 4234504 http://www.medworm.com/index.php?rid=4234503&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Accumulating data propose that active injecting drug users might not differ from the general population in terms of sustained virological response when adherent to therapy for chronic hepatitis C. However, current guidelines contain restrictive recommendations for therapy in this group of patients. OBJECTIVE: Therefore, we evaluated a cohort of chronic hepatitis C patients regarding the potent influence of active drug using on initial informed consent, compliance and sustained virological response to treatment. METHOD: For that purpose, 162 consecutive patients (of which 62 active injecting drug users), who had been evaluated during the last 6 years in our center for chronic hepatitis C and proposed to receive treatment with pegylated interferon alpha and ribavirin, were enrolled.... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234503 Tue, 07 Dec 2010 16:20:51 +0100 4234503 http://www.medworm.com/index.php?rid=4234502&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300004%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: In our center, after the introduction of MELD score as the priority criterion for liver transplantation there were an increased number of transplants with hepatocellular carcinoma. Excluding these patients, the receptors were operated upon with more advanced cirrhosis. Nevertheless the patients had the same need for red blood cells transfusion, intensive care unit and hospital stay and 3 months and 1 year survival.CONTEXTO: Atualmente o MELD é utilizado no Brasil como critério de seleção de receptores na lista de espera para transplante hepático. Esse sistema prioriza para o transplante os pacientes com cirrose hepática mais avançada. OBJETIVO: comparar os resultados do transplante hepático quando o tempo em lista de espera era o critério de alocação de órgãos (era... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234502 Tue, 07 Dec 2010 16:20:51 +0100 4234502 http://www.medworm.com/index.php?rid=4234501&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Morphofunctional staging is a valuable prognostic factor for colorectal cancer and it correlates with plasma CEA levels.CONTEXTO: Novas estratégias são necessárias à identificação de marcadores que promovam precisão no diagnóstico, no prognóstico e melhorem o tratamento de pacientes com câncer colorretal. OBJETIVO: Analisar características funcionais e morfológicas do câncer colorretal para identificar padrões de neoplasia que modificam a sobrevida. MÉTODOS: Quarenta e cinco pacientes com adenocarcinoma colorretal foram seguidos por no mínimo 3 anos. Níveis séricos de antígeno carcinoembrionário (CEA) foram mensurados por quimioluminescência e a análise imunoistoquímica da expressão tecidual do antígeno por meio de processamento de imagem assistida por ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234501 Tue, 07 Dec 2010 16:20:51 +0100 4234501 http://www.medworm.com/index.php?rid=4234500&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300002%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Considering the particularities of the endoscope and its reprocessing, it is imperative to establish protocols to ensure the quality of the disinfection and the prevention of cross-contamination.CONTEXTO: A segurança do procedimento endoscópico depende do uso de um aparelho adequadamente reprocessado e a qualidade do reprocessamento está relacionada a cada uma das etapas operacionais desse processo. OBJETIVO: Caracterizar o reprocessamento de endoscópios pelo uso do glutaraldeído em serviços de endoscopia. MÉTODOS: Estudo conduzido em 20 serviços de endoscopia digestiva do município de Goiânia, GO. A amostra se constituiu de endoscópios utilizados para endoscopia digestiva alta. Os dados foram obtidos mediante observação direta de 60 reprocessamentos de endoscópio... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234500 Tue, 07 Dec 2010 16:20:51 +0100 4234500 http://www.medworm.com/index.php?rid=4234499&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000300001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=4234499 Tue, 07 Dec 2010 16:20:51 +0100 4234499 http://www.medworm.com/index.php?rid=3883038&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200017%26lng%3Den%26nrm%3Diso%26tlng%3Den In the last decades, several improvements in the management of variceal bleeding have resulted in a significant decrease in morbidity and mortality of patients with cirrhosis and bleeding varices. Progress in the multidisciplinary approach to these patients has led to a better management of this disease by critical care physicians, hepatologists, gastroenterologists, endoscopists, radiologists and surgeons. In this respect, the Brazilian Society of Hepatology has, recently, sponsored a consensus meeting in order to draw evidence-based recommendations on the management of these difficult-to-treat subjects. An organizing committee comprised of four people was elected by the Governing Board and was responsible to invite 27 researchers from distinct regions of the country to make a systematic ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883038 Fri, 20 Aug 2010 06:13:45 +0100 3883038 http://www.medworm.com/index.php?rid=3883037&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200016%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: We review literature about the management of inflammatory bowel disease in pregnancy. Some studies are needed to ensure the best approach to inflammatory bowel disease in pregnant women.CONTEXTO: A doença inflamatória intestinal acomete mulheres em idade fértil com relativa frequência. A conduta exige maior atenção durante esta condição clínica em virtude dos riscos potenciais de complicações materno-fetais. RESULTADOS E CONCLUSÕES: Esta é uma revisão sobre as manifestações clínicas das doenças inflamatórias intestinais durante a gravidez e seu tratamento durante este período. Ainda são necessários estudos sobre o tema para melhor abordagem das doenças inflamatórias intestinais em gestantes. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883037 Fri, 20 Aug 2010 06:13:45 +0100 3883037 http://www.medworm.com/index.php?rid=3883036&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200015%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXTO: Os indivíduos alcoolistas apresentam aumento da concentração hepática de ferro e os mecanismos responsáveis por essa deposição são ainda desconhecidos. Apesar da extensa literatura existente sobre a absorção de ferro nos diferentes estados patológicos, os efeitos do consumo prolongado do etanol não estão totalmente esclarecidos. OBJETIVOS: Determinar a absorção de ferro no duodeno de camundongos após consumo prolongado de etanol, com relação ao controle de camundongos normais. MÉTODOS: Foram utilizados 10 camundongos machos da raça Swiss, distribuídos em dois grupos: grupo 1 (n = 5) - controle e grupo 2 (n = 5) - consumo de água com etanol, como única fonte de água ofertada. Os animais foram acompanhados durante 120 dias. Decorrido esse período, isolou-se... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883036 Fri, 20 Aug 2010 06:13:45 +0100 3883036 http://www.medworm.com/index.php?rid=3883035&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200014%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: The straight relationship between cirrhosis and impaired intestinal barrier has not been elucidated yet. OBJECTIVES: To verify 51Cr-EDTA-intestinal permeability in rats with CCl4-induced cirrhosis and controls. METHOD: Fifty male Wistar rats weighing 150-180 g were separated in three groups: 25 animals received CCl4 0.25 mL/kg with olive oil by gavage with 12 g/rat/day food restriction for 10 weeks (CCl4-induced cirrhosis); 12 received the same food restriction for 10 weeks (CCl4-non exposed). Other 13 rats received indomethacin 15 mg/kg by gavage as positive control of intestinal inflammation. RESULTS: The median (25-75 interquartile range) 51Cr-EDTA-IP values of cirrhotic and CCl4-non exposed rats were 0.90% (0.63-1.79) and 0.90% (0.60-1.52) respectively, without significant dif... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883035 Fri, 20 Aug 2010 06:13:45 +0100 3883035 http://www.medworm.com/index.php?rid=3883034&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The length of hydroxypropyl methylcellulose submucosal fluid cushion is longer in comparison with normal saline solution. The median time for carboxymethylcellulose was not longer than normal saline solution. Hydroxypropyl methylcellulose, in the concentration of 0.25%, may be a durable alternative for submucosal injection.CONTEXTO: A ressecção endoscópica mucosa é uma modalidade estabelecida para a excisão de lesões sésseis no trato gastrointestinal. A injeção de fluídos na submucosa cria uma coxim que pode prevenir lesão térmica e perfuração. OBJETIVO: Este estudo cego investiga o desempenho de três diferentes soluções para criar um coxim fluído submucoso no estômago suíno. MÉTODOS: Três soluções foram injetadas no estômago de nove porcos BR1: soro f... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883034 Fri, 20 Aug 2010 06:13:45 +0100 3883034 http://www.medworm.com/index.php?rid=3883033&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Multimodal protocol of perioperative care may enhance recovery after surgery. Based on evidence these new routines of perioperative care changed conventional prescriptions in surgery. OBJECTIVE: To evaluate the results of a multimodal protocol (ACERTO protocol) in elderly patients. METHODS: Non-randomized historical cohort study was performed at the surgical ward of a tertiary university hospital. One hundred seventeen patients aged 60 and older were submitted to elective abdominal operations under either conventional (n = 42; conventional group, January 2004-June 2005) or a fast-track perioperative protocol named ACERTO (n = 75; ACERTO group, July 2005-December 2007). Main endpoints were preoperative fasting time, postoperative day of re-feeding, volume of intravenous fluids, len... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883033 Fri, 20 Aug 2010 06:13:45 +0100 3883033 http://www.medworm.com/index.php?rid=3883032&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The pressure level of 8 mm Hg, as determined by the hepatic venous pressure gradient, does not define the presence or absence of ascites in the cirrhotic patient, and in view of the similarity between mean pressures in patients with or without peritoneal effusion, it is impossible to define a cut-off point for the emergence of such complication. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883032 Fri, 20 Aug 2010 06:13:45 +0100 3883032 http://www.medworm.com/index.php?rid=3883031&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The nonalcoholic fat liver disease fibrosis score has high accuracy to identify and exclude advanced liver fibrosis in morbidly obese patients subjected to bariatric surgery.CONTEXTO: Pacientes com obesidade mórbida apresentam risco significativo para doença hepática gordurosa não-alcoólica e para suas formas mais graves, a esteatohepatite e a cirrose hepática. O diagnóstico de tais alterações é importante, principalmente na avaliação pré-operatória de cirurgia bariátrica. Até o momento, a biopsia hepática é o procedimento com maior precisão para tal diagnóstico. OBJETIVO: Avaliar o escore de fibrose hepática em doença hepática gordurosa não-alcoólica em pacientes com obesidade mórbida na população brasileira. MÉTODOS: Foram incluídos 158 paciente... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883031 Fri, 20 Aug 2010 06:13:45 +0100 3883031 http://www.medworm.com/index.php?rid=3883030&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: HOMA-IR values above or equal to 2.0 or 2.5 show enhanced diagnostic value in distinguishing non-alcoholic fatty liver disease carriers from control group individuals.CONTEXTO: Pela sua boa correlação com o "clamp" glicêmico, o HOMA-IR tem sido largamente utilizado como índice de resistência insulínica em estudos clínicos e epidemiológicos em pacientes com doença hepática gordurosa não-alcoólica. Porém os valores utilizados para esse parâmetro têm sido muito variáveis. OBJETIVO: Identificar o valor de corte do HOMA-IR que melhor diferencie pacientes com doença hepática gordurosa não-alcoólica não-diabéticos, de um grupo controle. MÉTODOS: Foram estudados 116 pacientes com doença hepática gordurosa não-alcoólica, diagnosticados por critérios clínicos... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883030 Fri, 20 Aug 2010 06:13:45 +0100 3883030 http://www.medworm.com/index.php?rid=3883029&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Studies in the area of health economics are still poorly explored and it is known that the cost savings in this area is becoming more necessary, provided that strict criteria. OBJECTIVE: To perform a cost-effectiveness analysis of spinal anesthesia versus local anesthesia plus sedation for loop colostomy closure. METHODS: This was a randomized clinical trial with 50 patients undergoing loop colostomy closure either under spinal anesthesia (n = 25) or under local anesthesia plus sedation (n = 25). The duration of the operation, time spent in the post-anesthesia recovery room, pain, postoperative complications, length of hospital stay, laboratory and imaging examinations and need for rehospitalization and reoperation were analyzed. The direct medical costs were analyzed. A decision ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883029 Fri, 20 Aug 2010 06:13:45 +0100 3883029 http://www.medworm.com/index.php?rid=3883028&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Anterior, medium and posterior regions of the tongue, at both sides, had the same taste discriminative capacity. Nevertheless, closed mouth increased immediate and late recognition capacity by palate participation. It was possible to admit that palate participation increase the sapid perception in the mouth, by recruitment of the palate taste receptors and also by fluid compression and its scattering over tongue surface.CONTEXTO: O reconhecimento dos gostos tem importante papel para as condições nutricionais e também para a proteção da integridade do organismo contra a ingestão de alimentos potencialmente perigosos. OBJETIVO: Investigar a presença na língua de regiões com capacidade seletiva para percepção dos gostos básicos e também verificar se e como o palato p... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883028 Fri, 20 Aug 2010 06:13:45 +0100 3883028 http://www.medworm.com/index.php?rid=3883027&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The epidemiological findings of this study are similar to the ones of the worldwide literature. Indications of videolaparoscopy in retrospective analyses have the limitation of subjective evaluation of intestinal obstruction, which was included in this study as a relative contraindication to laparoscopy.CONTEXTO: A laparotomia é considerada o método de escolha para o tratamento cirúrgico de pacientes com obstrução intestinal sem resposta ao tratamento clínico conservador. Atualmente, no entanto, diversas publicações têm demonstrado a viabilidade da videolaparoscopia no tratamento da obstrução intestinal. OBJETIVO: Descrever o perfil clínicoepidemiológico de pacientes com obstrução intestinal submetidos ao tratamento cirúrgico e verificar a presença de contraind... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883027 Fri, 20 Aug 2010 06:13:45 +0100 3883027 http://www.medworm.com/index.php?rid=3883026&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The immunohistochemical expression of Ki-67 in colorectal cancer is associated with recurrence of this disease.CONTEXTO: Pesquisa de marcadores tumorais que permitam tratamento com maiores índices de sobrevida, além de indicarem a resposta ao tratamento e a recurrência da neoplasia. OBJETIVO: Analisar as expressões imunoistoquímicas das proteínas p53, bcl-2 e Ki-67 no adenocarcinoma colorretal, correlacionando-as com os fatores prognósticos clínico-patológicos. MÉTODO: Foram confeccionados blocos de parafina de TMA com tecido de adenocarcinoma colorretal ressecados cirurgicamente em 82 pacientes no Hospital São Paulo da Universidade Federal der São Paulo, São Paulo, SP, de 2002 a 2005, não submetidos a radio ou quimioterapia. Cortes de 4 µm foram submetidos a rea... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883026 Fri, 20 Aug 2010 06:13:45 +0100 3883026 http://www.medworm.com/index.php?rid=3883025&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200004%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The most common cystic neoplasms of the pancreas are serous and mucinous cysts. These tumors are more frequent in female. Although almost all serous cysts are benign, 40% of mucinous cysts are malign. Misdiagnosis may delay appropriate treatment and increase mortality.RACIONAL: O diagnóstico e tratamento das neoplasias císticas do pâncreas aumentaram significativamente nas últimas décadas. Existem poucas publicações brasileiras sobre estes tumores, sendo que a maioria é limitada à descrição de um ou poucos casos. OBJETIVO: Apresentar a experiência com 27 pacientes com neoplasia cística do pâncreas. MÉTODOS: Os dados demográficos, quadro clínico, exames complementares, procedimento cirúrgico com as suas complicações e a evolução pós-operatória de 27 paci... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883025 Fri, 20 Aug 2010 06:13:45 +0100 3883025 http://www.medworm.com/index.php?rid=3883024&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The incidence of ulcer in the gastrojejunal anastomosis within the first 2 months following Rouxen-Y gastric bypass under proton pump inhibitors is considerable. It was not related to the use of non-steroidal anti-inflammatory drugs, highlighting the possibility of ischemia and foreign body as causal factors. The ulcers were asymptomatic, and all post-surgical dyspeptic symptoms were moderate in severity.CONTEXTO: Sintomas dispépticos são comuns após derivação gástrica em Y-de-Roux. Podem decorrer de úlceras de boca anastomótica, cujos possíveis fatores causais incluem a secreção cloridropéptica da bolsa gástrica, isquemia, efeito de corpo estranho dos materiais de sutura e uso de antiinflamatórios não-esteróides. O esomeprazol é um redutor potente da secreçã... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883024 Fri, 20 Aug 2010 06:13:45 +0100 3883024 http://www.medworm.com/index.php?rid=3883023&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200002%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883023 Fri, 20 Aug 2010 06:13:45 +0100 3883023 http://www.medworm.com/index.php?rid=3883022&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000200001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3883022 Fri, 20 Aug 2010 06:13:45 +0100 3883022 http://www.medworm.com/index.php?rid=3619332&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100018%26lng%3Den%26nrm%3Diso%26tlng%3Den Laparoscopic colorectal surgery is believed to be technically and oncologically feasible. Robotic surgery is an attractive mode in performing minimally-invasive surgery once it has several advantages if compared to standard laparoscopic surgery. The aim of this paper is to report the first known case of colorectal resection surgery using the robotic assisted surgical device in Brazil. A 35-year-old woman with deep infiltrating endometriosis with rectal involvement was referred for colorectal resection using da Vinci® surgical system. The authors also reviewed the most current series and discussed not only the safety and feasibility but also the real benefits of robotic colorectal surgeryA cirurgia laparoscópica colorretal é considerada tecnicamente factível e segura, com resultados onc... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619332 Wed, 02 Jun 2010 13:18:14 +0100 3619332 http://www.medworm.com/index.php?rid=3619331&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100017%26lng%3Den%26nrm%3Diso%26tlng%3Den Gastroesophageal reflux disease (GERD) is one of the most common disorders in medical practice. A number of guidelines and recommendations for the diagnosis and management of GERD have been published in different countries, but a Brazilian accepted directive by the standards of evidence-based medicine is still lacking. As such, the aim of the Brazilian GERD Consensus Group was to develop guidelines for the diagnosis and management of GERD, strictly using evidence-based medicine methodology that could be clinically used by primary care physicians and specialists and would encompass the needs of physicians, investigators, insurance and regulatory bodies. A total of 30 questions were proposed. Systematic literature reviews, which defined inclusion and/or exclusion criteria, were conducted to ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619331 Wed, 02 Jun 2010 13:18:14 +0100 3619331 http://www.medworm.com/index.php?rid=3619330&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100016%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Through this literature review, it was possible to achieve positive answers as regards the use of probiotics and prebiotics in carcinogenesis, which can be adequately recommended. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619330 Wed, 02 Jun 2010 13:18:14 +0100 3619330 http://www.medworm.com/index.php?rid=3619329&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100015%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: The diet used was able to induce steatosis and nonalcoholic steatohepatitis. Besides vitamin E showed to reduce the liver oxidative stress, as well as the fibrosis developmentCONTEXTO: Ainda não há um tratamento comprovadamente eficaz para a esteatohepatite não-alcoólica. OBJETIVO: Desenvolver um modelo experimental de esteatohepatite não-alcoólica induzida por dieta deficiente em metionina e colina, bem como avaliar o papel do metformina, da vitamina E e da sinvastatina na evolução da esteatohepatite não-alcoólica. MÉTODOS: Foram estudados prospectivamente 50 ratos da linhagem Wistar, por um período de 90 dias, sendo os mesmos divididos em cinco grupos de 10 ratos. Um grupo recebeu ração convencional e os demais a dieta deficiente em metionina e colina. Dentre o... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619329 Wed, 02 Jun 2010 13:18:14 +0100 3619329 http://www.medworm.com/index.php?rid=3619327&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100014%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Taken together, these results suggest the potential therapeutic use of this hepatotrophic factors solution to treat chronic liver diseases.CONTEXTO: A fibrose hepática ocorre em resposta a diversos agentes agressores e é um fator predisponente da cirrose. Fatores hepatotróficos são conhecidos por estimular o crescimento hepático e restaurar a arquitetura histológica do fígado. Promovem, também, melhora na função hepática e aceleram a reversão da fibrose antes de sua progressão para cirrose. OBJETIVO: Testar os efeitos de uma solução de fatores hepatotróficos, composta por aminoácidos, vitaminas, glicose, insulina, glugacon e triiodotironina na fibrose hepática em ratos. MéTODOS: No presente estudo, a fibrose foi induzida em ratos pela administração de dimet... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619327 Wed, 02 Jun 2010 13:18:14 +0100 3619327 http://www.medworm.com/index.php?rid=3619326&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The data allow us to suggest that the observed oxidative stress is related to the damages caused by carbon tetrachloride and that the use of melatonin can minimize these damagesCONTEXTO: A cirrose é uma hepatopatia crônica e progressiva que constitui estágio irreversível de disfunção hepática. É associada a alterações na circulação sistêmica. OBJETIVOS: Avaliar o estresse oxidativo no sangue de ratos cirróticos e tratados com antioxidante melatonina. MÉTODOS: A cirrose foi induzida através da inalação de tetracloreto de carbono. Foram avaliadas as provas de integridade hepática através das medidas das enzimas séricas, o dano oxidativo medido pela lipoperoxidação e a atividade das enzimas antioxidantes no eritrócito. No fígado desses animais, foram avali... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619326 Wed, 02 Jun 2010 13:18:14 +0100 3619326 http://www.medworm.com/index.php?rid=3619325&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: In our Service, the prevalence of gastroesophageal reflux disease associated with acid reflux in infants revealed elevated. Infants with crisis of cyanosis/apnea constitute risk population for gastroesophageal reflux disease in which diagnostic investigation needs to be considered.CONTEXTO: Em lactentes, nem sempre é fácil diferenciar o refluxo gastroesofágico fisiológico do patológico baseado somente em dados clínicos. No nosso meio, são escassos os estudos sobre doença do refluxo gastroesofágico em lactentes, sendo ainda mais raros os que tenham utilizado a pHmetria esofágica prolongada para a sua avaliação. OBJETIVO: Descrever os aspectos clínicos da doença do refluxo gastroesofágico e determinar a sua prevalência em uma população de lactentes com refluxo ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619325 Wed, 02 Jun 2010 13:18:14 +0100 3619325 http://www.medworm.com/index.php?rid=3619324&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: A prevalence of 2.3% was found among symptomatic 12- to 36-month-old children that had not been previously diagnosed as celiac.CONTEXTO: O diagnóstico correto da doença celíaca em crianças ambientalmente carentes é frequentemente dificultado pela presença usual de causas outras para os clássicos sintomas da doença celíaca. OBJETIVO: Determinar a prevalência de doença celíaca em um grupo de crianças com idades compreendidas entre 12 e 36 meses, utilizando a pesquisa de anticorpos antigliadina (IgG e IgA-AGA), antiendomísio (IgA-EMA) e antitransglutaminase recombinante humana (IgA-tTG) como método de rastreio. MÉTODOS: Foram incluídas no estudo 214 crianças (114 meninos), com 12 a 36 meses de idade, todas em uso de dieta contendo glúten. Em todos os soros foi p... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619324 Wed, 02 Jun 2010 13:18:14 +0100 3619324 http://www.medworm.com/index.php?rid=3619323&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Other environmental and genetic factors might contribute to determining the disease. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619323 Wed, 02 Jun 2010 13:18:14 +0100 3619323 http://www.medworm.com/index.php?rid=3619322&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Patients with ulcerative colitis followed up on an outpatient basis tend to be well nourished. However, the nutritional aspects studied tend to worsen during the period of inflammatory disease activity.CONTEXTO: A retocolite ulcerativa inespecífica compreende uma das doenças inflamatórias intestinais, com características de inflamação superficial da mucosa do cólon, reto, ânus, podendo incluir o íleo terminal. Caracteriza-se por várias exonerações diárias, com a presença de sangue e/ou pus, cursando em períodos de atividade e remissão inflamatória intestinal. OBJETIVO: Comparar os parâmetros nutricionais (alimentares, bioquímicos e antropométricos) em pacientes com retocolite ulcerativa inespecífica acompanhados em ambulatório, durante a atividade e remiss... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619322 Wed, 02 Jun 2010 13:18:14 +0100 3619322 http://www.medworm.com/index.php?rid=3619320&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: It is possible to suppose that in the subconscious condition, swallowing apnea is integrated under coordination of the same control mechanism that also involves the elastic resistance of the lung.CONTEXTO: Apesar do expressivo número de estudos sobre a coordenação da respiração com a deglutição, o tema permanece aberto à pesquisa. OBJETIVO: Identificar um padrão de coordenação entre a pausa respiratória e a deglutição que ocorre em associação a esta usual apneia (apneia de deglutição) e estabelecer a importância do fechamento das pregas vocais que ocorre em associação a esta apneia. MÉTODOS: Foram estudados 66 adultos de ambos os sexos, incluindo voluntários sadios, indivíduos laringectomizados e pacientes com queixas digestivas sem disfagia. Apneias pro... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619320 Wed, 02 Jun 2010 13:18:14 +0100 3619320 http://www.medworm.com/index.php?rid=3619319&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Buriticupu may be considered endemic for hepatitis B and C. Hepatitis B infection could be related to precarious living conditions and old age. Hepatitis C was not associated with the variables investigated in the present investigation.CONTEXTO: Infecção por hepatites B e C tem sido causa importante de morbimortalidade em todo o mundo. Entretanto, há poucas investigações sobre a prevalência e possíveis fatores de risco relacionados a tais doenças no Brasil, especialmente na região amazônica, onde há algumas regiões endêmicas para tais quadros clínicos. OBJETIVOS: Detectar a prevalência de hepatites B e C na cidade de Buriticupu, MA, localizada na região leste da Amazônia brasileira, e tentar investigar seus fatores de risco nessa área. MÉTODOS: Duzentos e qua... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619319 Wed, 02 Jun 2010 13:18:14 +0100 3619319 http://www.medworm.com/index.php?rid=3619318&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXTO: Doentes com doença renal crônica em tratamento hemodialítico apresentam risco aumentado de aquisição do vírus da hepatite C (VHC). Elevadas taxas de prevalência têm sido detectadas em unidades de diálise do mundo inteiro. Estudos recentes têm demonstrado que a infecção pelo VHC interfere de forma negativa na sobrevida dos pacientes em hemodiálise e naqueles submetidos ao transplante renal. OBJETIVOS: Determinar a prevalência e os fatores de risco da infecção pelo VHC em pacientes submetidos a hemodiálise. MÉTODOS: Realizou-se estudo transversal entre janeiro e dezembro de 2007. Neste período, 236 pacientes em hemodiálise foram testados pelo ELISA de terceira geração. Os casos positivos foram submetidos a pesquisa qualitativa do HCV-RNA pelo método de PCR. C... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619318 Wed, 02 Jun 2010 13:18:14 +0100 3619318 http://www.medworm.com/index.php?rid=3619317&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: The prevalence of diabetes mellitus, impaired glucose tolerance, insulin resistance and protein calorie malnutrition is high in cirrhotic patients on the waiting list for liver transplantation. There were more infectious complications and/or deaths in a 3-month follow-up period in patients with diabetes mellitus diagnosed by oral glucose tolerance test. Oral glucose tolerance test seems to be indicated as a routine practice in this population.CONTEXTO: Cirrose, diabetes mellitus, intolerância à glicose e resistência insulínica é uma associação que vem sendo discutida, bem como a desnutrição nesta população, pelo risco de pior evolução de hepatopatia. OBJETIVO: Determinar a prevalência de diabetes mellitus, intolerância à glicose e resistência insulínica e desn... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619317 Wed, 02 Jun 2010 13:18:14 +0100 3619317 http://www.medworm.com/index.php?rid=3619316&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100004%26lng%3Den%26nrm%3Diso%26tlng%3Den Conclusion - Sour taste stimuli associated to cold temperature cause significant change in swallowing patterns, by shortening the pharyngeal transit time, which may lead to positive effects in patients with oropharyngeal dysphagia.CONTEXTO: O efeito do sabor azedo e as variações da temperatura dos alimentos em indivíduos disfágicos, ainda não foi totalmente esclarecidos. OBJETIVO: Verificar o efeito do sabor azedo e da temperatura fria no tempo de trânsito faríngeo da deglutição em indivíduos após acidente vascular encefálico hemisférico isquêmico. MÉTODOS: Participaram deste estudo 30 indivíduos adultos, sendo 16 do gênero masculino e 14 do feminino, destros, com faixa etária variando de 41 a 88 anos (média de 62,3 anos) e ictus que variou de 1 a 30 dias (mediana de 6 d... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619316 Wed, 02 Jun 2010 13:18:14 +0100 3619316 http://www.medworm.com/index.php?rid=3619315&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: We concluded that the most prevalent genotype found was D. However, further studies are needed to allow us to evaluate the implications of genetic variability in the clinical evolution of HBV carriers.CONTEXTO: Nos últimos anos a genotipagem do vírus da hepatite B (VHB) tem sido considerado fator relevante para a história natural da doença. OBJETIVOS: Determinar os genótipos do VHB e suas implicações clínicas e epidemiológicas, em uma coorte de pacientes em um hospital de Porto Alegre, RS, sul do Brasil. MÉTODOS: Foram avaliados 67 pacientes com marcadores de infecção crônica pelo VHB que estavam sendo tratados no Complexo Hospitalar Santa Casa de Porto Alegre, RS. Foi aplicado um protocolo com dados demográficos e epidemiológicos dos pacientes, e AgHBe e ALT for... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619315 Wed, 02 Jun 2010 13:18:14 +0100 3619315 http://www.medworm.com/index.php?rid=3619314&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100002%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: This work suggests that CDH1 gene methylation and H. pylori infection are frequent events in samples from Brazilian patients with chronic gastritis and reinforces the correlation between H. pylori infection and CDH1 inactivation in early steps of gastric tumorigenesis.CONTEXTO:O câncer gástrico é uma das principais neoplasias que causam o óbito no Brasil e no mundo. Helicobacter pylori é um carcinógeno do tipo I relacionado à gastrite crônica. Diferenças no grau de virulência de suas cepas levam a maior risco de desenvolvimento de doenças gástricas. A metilação de ilhas CpGs está envolvida com o processo de tumorigênese em diferentes tipos de câncer. CDH1 é um gene supressor tumoral que, quando inativado, pode aumentar as chances de metástase. A metilação d... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619314 Wed, 02 Jun 2010 13:18:14 +0100 3619314 http://www.medworm.com/index.php?rid=3619313&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032010000100001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3619313 Wed, 02 Jun 2010 13:18:14 +0100 3619313 http://www.medworm.com/index.php?rid=3360831&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400017%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: 1) most patients with non-advanced megaesophagus were eutrophic; 2) surgical treatment led to improvement in nutritional status and increase of HDL cholesterol fraction. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360831 Sat, 13 Mar 2010 14:23:58 +0100 3360831 http://www.medworm.com/index.php?rid=3360830&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400016%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: We conclude that reoxygenation after hypoxia significantly increased the lesion of cultured rat hepatocytes when compared to simple hypoxia. Prostaglandin E1, superoxide dismutase, allopurinol and verapamil acted as cytoprotectors to the rat cultured hepatocytes submitted to hypoxia + reoxygenation in vitro. The substances prostaglandin E1, superoxide dismutase and verapamil protected hepatocytes submitted to simple hypoxia on the basis of all the criteria studied in this experimental model.CONTEXTO: A exposição dos hepatócitos a condições patológicas em que ocorram microambientes de hipóxia e reoxigenação são muito frequentes em doenças hepáticas. Várias substâncias apresentam perspectivas de ação citoprotetora para hepatócitos submetidos a reoxigenação apÃ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360830 Sat, 13 Mar 2010 14:23:58 +0100 3360830 http://www.medworm.com/index.php?rid=3360829&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400015%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Chronic active gastritis was observed in all patients with H. pylori infection. However, antral or corporeal predominance was not observed in most patients. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360829 Sat, 13 Mar 2010 14:23:58 +0100 3360829 http://www.medworm.com/index.php?rid=3360828&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400014%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Our results indicate that right lateral and prone positions have influence on the cardiorespiratory effect, where left lateral and supine are the positions who presented higher negative effect in the newborns submitted to the increase of the gastric volume. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360828 Sat, 13 Mar 2010 14:23:58 +0100 3360828 http://www.medworm.com/index.php?rid=3360827&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: In this selected population, there was no association between the immunomarkers, p53, cyclin D1 and bcl-2 and clinicopathological data and/or overall survival.CONTEXTO: O adenocarcinoma da junção esôfago-gástrica tem um comportamento agressivo e o estádio TNM não é sempre suficiente para categorizar o paciente de acordo com a evolução do mesmo. OBJETIVO: Avaliar a imunoexpressão do p53, ciclina D1 e Bcl-2 em pacientes com adenocarcinoma da junção esôfago-gástrica sem esôfago de Barrett e comparar com as características clínicas e sobrevida. MÉTODOS: Cortes histológicos de 75 adenocarcinomas da esôfago-gástrica ressecados de 1991 a 2003 foram analisados por imunoistoquímica para o p53, ciclina D1 e Bcl-2, usando-se o método da estreptavidina-biotina-peroxi... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360827 Sat, 13 Mar 2010 14:23:58 +0100 3360827 http://www.medworm.com/index.php?rid=3360826&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400012%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: It was possible to observe a significant relationship between tracheal aspiration incidence and pressure controlled ventilation mode, which means the inclusion of those patients in the risk group for oropharyngeal dysphagia and their insertion in prevention protocols. The relationship between tracheal aspiration and sedation level, as well as tracheal aspiration and mechanical ventilation, were not statistically significant in this sample, needing further research.CONTEXTO: Muitos pacientes em uso de ventilação mecânica apresentam complicações clínicas por apresentarem aspiração traqueal. Métodos de avaliação e detecção precoce são necessários para que medidas preventivas e de segurança se estabeleçam nessa população. OBJETIVO: Pesquisar a incidência de aspi... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360826 Sat, 13 Mar 2010 14:23:58 +0100 3360826 http://www.medworm.com/index.php?rid=3360825&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400011%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXT: Drink tests constitute an inexpensive and non-invasive tool, which has been proposed to discriminate individuals with altered fluid intake, as dyspeptics. However, their use in everyday clinical practice is still limited as standardization still lacks. OBJECTIVE: To perform a direct, paired comparison between the water and the nutrient drink test in normal volunteers. METHODS: Thirty eight normal volunteers (19 males, 19 females, mean age 24.4 ± 0.4 years) underwent drink test with water and nutrient (Nutridrink) within 7-10 days. Both tests included a loading (consumption of 100 mL/min for water and 15 mL/min for Nutridrink for the longest possible period of time) and a recuperation phase (observation after cessation of fluid intake), being separated by the maximal saturation po... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360825 Sat, 13 Mar 2010 14:23:58 +0100 3360825 http://www.medworm.com/index.php?rid=3360824&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400010%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: In this series, fibrin glue treatment for complex cryptoglandular anal fistulas achieved a very low healing rate. Our results do not support the use of fibrin glue as a first-line treatment for patients with this type of fistula.CONTEXTO: O manejo das fistulas anais complexas está associado ao risco de lesão esfincteriana e incontinência fecal. Recentemente, a cola de fibrina surgiu como uma alternativa de tratamento conservador de esfíncter para as fístulas anais, porém até o momento não se chegou a um consenso quanto à eficácia do método. OBJETIVO: Avaliar o uso da cola de fibrina especificamente no tratamento de fístulas anais complexas de origem criptoglandular. MÉTODOS: Foram estudados pacientes com fístulas anais complexas tratados com cola de fibrina entre... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360824 Sat, 13 Mar 2010 14:23:58 +0100 3360824 http://www.medworm.com/index.php?rid=3360823&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400009%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: 1. Operative complications occurred in about one third of the patients, being more frequently after the confection of ileal reservoir; 2. greater age and previous colonic carcinoma were associated with the development of rectal cancer after ileorectal anastomosis; 3. patients treated by restorative proctocolectomy are not free from the risk of pouch degeneration; 4. the disease complexity and the various risk factors (clinical, endoscopic, genetic) indicate that the best choice for operative treatment should be based on individual features discussed by a specialist; 5. all patients require continuous and long-term surveillance during postoperative follow-up.CONTEXTO: As controvérsias quanto a melhor forma de tratamento da polipose adenomatosa familiar confrontam a morbidade d... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360823 Sat, 13 Mar 2010 14:23:58 +0100 3360823 http://www.medworm.com/index.php?rid=3360822&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400008%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Carcinoid tumors of the colon are frequently right-sided and may be clinically occult until an advanced stage is reached. Based on the relatively poor survival rates reported, it is recommended that, in addition to standard surgical resection, vigorous surveillance for metastatic disease must be performed, particularly during the first 2 years after surgery. In addition, these patients require evaluation of the entire gastrointestinal tract for evidence of coexisting malignancy, along with an extended period of follow-up, because tumor recurrences after 5 years are not uncommon.CONTEXTO: Carcinóides cólicos, excluindo aqueles que se originam no apêndice cecal, são extremamente raros. Devido a esta raridade, as características e comportamento desta neoplasia permanecem ind... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360822 Sat, 13 Mar 2010 14:23:58 +0100 3360822 http://www.medworm.com/index.php?rid=3360821&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400007%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: We conclude that there is a difference between men and women in the proximal esophageal contractions in response to wet swallows, although this difference is of no clinical relevance.CONTEXTO: Há trabalhos que demonstram a existência de diferenças entre homens e mulheres na deglutição e nas contrações em parte distal do esôfago. OBJETIVO: Neste trabalho estuda-se a influência do gênero nas contrações em parte proximal do esôfago de pessoas assintomáticas. MÉTODO: Incluíram-se 20 homens (22-68 anos, mediana 39 anos) e 44 mulheres (18-61 anos, mediana 41 anos) sem doenças gastrointestinais, neurológicas ou respiratórias. Mediu-se o intervalo de tempo entre o início da contração em faringe 1 cm proximal ao esfíncter superior do esôfago e o início da contra... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360821 Sat, 13 Mar 2010 14:23:58 +0100 3360821 http://www.medworm.com/index.php?rid=3360820&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400006%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Intramural esophageal hematoma is a rare complication of esophageal variceal sclerotherapy and its incidence in our institution was similar to those observed in the literature. Our study suggests that this complication occurs as a result of a fragile esophageal mucosa after previous esophageal variceal sclerotherapy sessions. Impaired coagulation, although not essential, could contribute to hematoma formation and extension through esophageal submucosa.CONTEXTO: Apesar do fato de que a escleroterapia endoscópica de varizes esofágicas vem sendo largamente substituída pela técnica de ligadura elástica, a escleroterapia é ainda rotineiramente utilizada em muitas instituições, especialmente em países em desenvolvimento. O hematoma intramural esofágico é uma complicação ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360820 Sat, 13 Mar 2010 14:23:58 +0100 3360820 http://www.medworm.com/index.php?rid=3360819&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400005%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Higher morbidity and mortality was related with complex injuries of the pancreas (grade IV and V), but morbidity and mortality in the group of injuries grade I and II are not minimal in patients with changed values of revised trauma score and high values of injury severity score and abdominal trauma index. Systolic blood pressure lower 90 mm Hg, changed values of revised trauma score index, values of injury severity score higher 15 and values of abdominal trauma index higher 25 are predictive factors of morbidity. Changed values of revised trauma score, values of injury severity score or abdominal trauma index higher 25, systolic blood pressure are predictive factors of mortality in patients with pancreatic trauma. Low values of TRISS are predictive of higher morbidity and mor... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360819 Sat, 13 Mar 2010 14:23:58 +0100 3360819 http://www.medworm.com/index.php?rid=3360818&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400004%26lng%3Den%26nrm%3Diso%26tlng%3Den Conclusions - This experience is similar to those described in the world literature. Celiac disease presents the same characteristics independently of the geographic region. We recommend periodic evaluations, from childhood, independent of the duration of the diet. The key is to establish an interval between evaluations.CONTEXTO: A doença celíaca é uma enfermidade multissistêmica e autoimune que pode se manifestar em qualquer idade, em indivíduos geneticamente predispostos. OBJETIVO: Identificação das associações, complicações e causas de morte em pacientes brasileiros após longo período de acompanhamento. MÉTODOS: Foram estudados retrospectivamente 157 pacientes, 23 adolescentes e 134 adultos, 79,6% do sexo feminino e 20,4% do masculino, 75,8% ao diagnóstico e 24,2% em diet... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360818 Sat, 13 Mar 2010 14:23:58 +0100 3360818 http://www.medworm.com/index.php?rid=3360817&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400003%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Patients with chronic liver disease showed higher risk of developing gastroduodenal lesions regardless of the presence of the H. pylori infection. (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360817 Sat, 13 Mar 2010 14:23:58 +0100 3360817 http://www.medworm.com/index.php?rid=3360816&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400002%26lng%3Den%26nrm%3Diso%26tlng%3Den Existe, atualmente, grande demanda para se aumentar a eficiência do ato médico e isto pode ser alcançado através de pesquisas de avaliação de tecnologia em saúde, a ATS. Esta visa, por um lado, determinar a melhor evidência de eficácia ou efetividade de um dado tratamento em saúde, por outro, determinar os custos associados com tal tratamento médico. Somente as alternativas com custo e efetividade comprovados, ou seja, que sejam eficientes, serão adotados doravante nos hospitais e sistemas de saúde público e privados. Exemplo são os custos crescentes de tratamentos com biológicos, por exemplo, em doença inflamatória intestinal ou hepatites virais, ou mesmo em oncologia. Há necessidade de se desenvolver pesquisas em ATS para a identificação não somente dos tratamentos ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360816 Sat, 13 Mar 2010 14:23:58 +0100 3360816 http://www.medworm.com/index.php?rid=3360815&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000400001%26lng%3Den%26nrm%3Diso%26tlng%3Den (Source: Arquivos de Gastroenterologia) Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=3360815 Sat, 13 Mar 2010 14:23:58 +0100 3360815 http://www.medworm.com/index.php?rid=2964930&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000300019%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Although the trials have shown efficacy of LOLA in reducing hyperammonemia of hepatic encephalopathy, sufficient evidence of a significant beneficial effect of LOLA on patients with hepatic encephalopathy was not found. The studies performed in this area were small, with short follow-up periods and half of them showed low methodological quality.CONTEXTO: Estudos experimentais e clínicos sugerem que a L-ornitina-L-aspartato pode ter uma influência favorável na encefalopatia hepática em virtude do seu efeito na redução da amônia, e melhora dos sintomas e achados laboratoriais. OBJETIVOS: Avaliar e analisar criticamente os estudos de eficácia e/ou efetividade do uso de L-ornitina-L-aspartato quando comparado com placebo no tratamento da encefalopatia hepática. FONTES DE ... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=2964930 Fri, 06 Nov 2009 14:16:51 +0100 2964930 http://www.medworm.com/index.php?rid=2964929&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000300018%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Exclusion of cardiac disease is of crucial importance. On the other hand non-cardiac chest pain could be related to gastrointestinal, muscular and respiratory causes and/or psychological disturbances. Treatment aims to attack mechanism generator in order to relieve or to eliminate symptoms. Drugs are the cornerstone of treatment, exception to achalasia patients because those have better response to dilation of the esophagus or surgery, and to those who need intensive pyschological therapy. The most important drugs used are proton pump inhibitors and triciclic antidepressants, the latter, to modulate central signal process (visceral hypersensitivity) and autonomic response. Recently, new diagnostic facilities, and also therapeutic modalities, such as esophageal botulin toxin in... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=2964929 Fri, 06 Nov 2009 14:16:51 +0100 2964929 http://www.medworm.com/index.php?rid=2964928&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000300017%26lng%3Den%26nrm%3Diso%26tlng%3Den In conclusion, duodenal bypass do not decrease glucose levels in lean individuals treated for gastric cancer.Alterações no metabolismo da glucose após cirúrgias bariátricas podem ser creditadas ao desvio do duodeno. Este estudo avaliou o efeito do desvio do duodeno nos níveis glicêmicos de pacientes magros submetidos a gastrectomia por câncer. Foram revistos 56 pacientes não-diabéticos e 6 pacientes diabéticos submetidos a gastrectomia com reconstrução em Y-de-Roux por câncer (gastrectomia parcial em 66% e total em 34%). Os níveis glicêmicos não se alteraram significantemente depois da operação (P = 0,5). Houve melhora do diabetes em um paciente com medicação oral. Em conclusão, o desvio duodenal não diminui os níveis glicêmicos de indivíduos magros tratados por c... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=2964928 Fri, 06 Nov 2009 14:16:51 +0100 2964928 http://www.medworm.com/index.php?rid=2964927&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000300016%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXTO: As hepatites virais constituem doença de notificação compulsória e apresentam grande importância em nosso meio devido à elevada prevalência. OBJETIVO: Comparar o perfil epidemiológico dos casos confirmados de hepatites B e C notificados no Núcleo de Vigilância Epidemiológica do Hospital do Servidor Público Estadual de São Paulo, São Paulo, SP, no período entre janeiro de 2004 e abril de 2007. MATERIAL: Os resultados foram analisados através do teste do qui ao quadrado. RESULTADOS: Observou-se 112 casos confirmados de hepatite B e 651 de hepatite C. Houve predominância do sexo masculino dentre os casos de hepatite B e do sexo feminino entre os de hepatite C, com significância estatística. A faixa etária mais frequente foi de 30 a 39 anos, considerando-se hepati... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=2964927 Fri, 06 Nov 2009 14:16:51 +0100 2964927 http://www.medworm.com/index.php?rid=2964926&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000300015%26lng%3Den%26nrm%3Diso%26tlng%3Den CONTEXTO: O adequado diagnóstico do estado nutricional é de vital importância para a prescrição da terapia nutricional enteral no ambiente hospitalar. OBJETIVO: Avaliar indicadores do estado nutricional em pacientes ingressantes na terapia nutricional enteral em uma unidade hospitalar. MÉTODOS: Estudo transversal com 100 pacientes adultos, sendo analisado o estado nutricional de ingresso à terapia nutricional enteral, por meio do índice de massa corporal obtido do peso e estatura estimados a partir de fórmulas de predição, e de indicadores laboratoriais do estado metabólico e nutricional. RESULTADOS: Do total, 29% dos pacientes foram classificados como desnutridos pelo índice de massa corporal, enquanto 80% dos mesmos apresentaram albumina abaixo do valor de referência ( Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=2964926 Fri, 06 Nov 2009 14:16:51 +0100 2964926 http://www.medworm.com/index.php?rid=2964925&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000300014%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSIONS: Treatment of HRS-1 with terlipressin and high-dose albumin was not associated with reversal of renal failure, but most of the treated subjects had severe end-stage liver disease with high MELD scores as well as high baseline creatinine values, parameters previously associated with bad outcomes.CONTEXTO: O tratamento da síndrome hepatorrenal do tipo 1 (SHR-1) com vasoconstritores esplâncnicos e albumina intravenosa tem se associado, em relatos de caso e estudos piloto não-controlados, à reversão da insuficiência renal em 60%-80% dos pacientes tratados. OBJETIVO: Avaliar os resultados do tratamento da SHR-1 com terlipressina e albumina. MÉTODOS: Foram avaliados, retrospectivamente, todos os pacientes hospitalizados com o diagnóstico de SHR-1 que se submeteram a tratament... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=2964925 Fri, 06 Nov 2009 14:16:51 +0100 2964925 http://www.medworm.com/index.php?rid=2964924&cid=s_37422_17_f&fid=37422&url=http%3A%2F%2Fwww.scielo.br%2Fscielo.php%3Fscript%3Dsci_arttext%26pid%3DS0004-28032009000300013%26lng%3Den%26nrm%3Diso%26tlng%3Den CONCLUSION: Since upper gastrointestinal endoscopy is part of the functional dyspepsia investigation and serology for anti-CagA antibody is not available in daily clinical practice, by biopsying gastric mucosa we would only be able to selectively apply H. pylori eradication therapy for those with histology that best correlate with virulent infecting strains (moderate or severe gastritis) - around ¼ of our study patients with dyspepsia.CONTEXTO: O benefício da terapia de erradicação do H. pylori como parte do tratamento da dispepsia funcional ainda é uma questão em aberto. Diferenças na distribuição geográfica, a ampla variabilidade genética e o fato de que a expressão clínica da infecção está fortemente relacionada com a virulência das cepas infectantes, são fatores que p... Arquivos de Gastroenterologia journals http://www.medworm.com/rss/comments.php?id=2964924 Fri, 06 Nov 2009 14:16:51 +0100 2964924