MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'BMC Dermatology' source. Wed, 08 Feb 2012 13:12:28 +0100 http://www.medworm.com/index.php?rid=5524747&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F16 The objective of this study was to assess the impact of melasma on quality of life by using a health status measurement - the Dermatology Life Quality Index (DLQI) - and a preference-based measurement - Willingness to Pay (WTP) and Time Trade-Off (TTO). Methods: A cross-sectional descriptive study was conducted. Seventy-eight patients with melasma who attended the melasma clinic at Siriraj Hospital from February to March 2009 were recruited in this study. The Thai version of the DLQI, questionnaires about WTP, standard TTO, and daily TTO were used to assess patients' quality of life. Results: Seventy-seven (98.7%) patients were female with a mean age of 47.8 7.9 years. The mean health utility based on standard TTO was 0.96. The utility obtained by the daily TTO method was 0.92 and was sign... BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=5524747 Mon, 19 Dec 2011 05:00:00 +0100 5524747 http://www.medworm.com/index.php?rid=5400800&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F15 Conclusion: This is the largest reported series in our context. In Morocco, CKS exhibits some special characteristics including a disseminated skin disease at diagnosis especially in men, a more common visceral or lymph node involvement and a less frequent association with second malignancies. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=5400800 Fri, 11 Nov 2011 05:00:00 +0100 5400800 http://www.medworm.com/index.php?rid=5161844&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F14 Conclusion: Ovicidal efficacy varied substantially among treatments, from 3.3% to 68.3%. The "suffocation" pediculicide and the melaleuca oil and lavender oil pediculicide (TTO/LO) were significantly more ovicidal than eucalyptus oil and lemon tea tree oil pediculicide (EO/LTTO) (P (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=5161844 Tue, 23 Aug 2011 23:00:00 +0100 5161844 http://www.medworm.com/index.php?rid=4936989&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F13 Conclusions: Evidence of the effectiveness of PDT for Paget's disease is promising, but limited. This may, in part, be explained by the rarity of the condition, making controlled comparative clinical trials challenging. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4936989 Tue, 14 Jun 2011 23:00:00 +0100 4936989 http://www.medworm.com/index.php?rid=4904255&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F12 Conclusions: It was observed that the MU can be a useful tool for early skin cancer diagnosis and treatment. This program probably is important, especially in developing countries with inadequate public health systems and social inequality. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4904255 Sun, 05 Jun 2011 23:00:00 +0100 4904255 http://www.medworm.com/index.php?rid=4842883&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F11 Conclusion Having sibling(s) with eczema strengthened the associations between maternal and paternal reports on eczema with eczema in index child only when exposure was reported at 1 year. These findings indicate that results from questionnaires-based studies of family eczema-history depend on whether or not index child has yet developed eczema.Trial registration The PACT study has been assigned ISRCTN28090297 in the international Current Controlled Trials database. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4842883 Thu, 19 May 2011 23:00:00 +0100 4842883 http://www.medworm.com/index.php?rid=4831573&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F10 Conclusions: The Global Resource of Eczema Trials has been created to facilitate knowledge mobilization into healthcare and to reduce wastage of research time through unnecessary duplication. The collective time saved by research groups around the world can now be used to make strides in optimising the treatment of eczema, in order to further benefit people with eczema. The database can be accessed free of charge at www.greatdatabase.org.uk (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4831573 Tue, 17 May 2011 23:00:00 +0100 4831573 http://www.medworm.com/index.php?rid=4736121&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F9 Conclusions: We propose that COCA constitutes a good experimental system for in vitro and in vivo skin modelling. Also, cell lines from genetically modified mice of interest in skin biology could be established using the method we have developed. COCA keratinocytes would be a suitable control, within a similar background, when studying the biological implications of these alterations. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4736121 Wed, 20 Apr 2011 23:00:00 +0100 4736121 http://www.medworm.com/index.php?rid=4710256&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F8 Conclusion: Dermatological disorders are common among patients admitted to medical wards and many are not detected by their referring or admitting physicians. Basic dermatological education should be emphasized to improve knowledge and awareness among clinicians. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4710256 Wed, 13 Apr 2011 23:00:00 +0100 4710256 http://www.medworm.com/index.php?rid=4659428&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F7 Conclusion: Although, the response to corticosteroid plus zinc sulfate was more than corticosteroid, there was no statistically significant difference between them. It appeared that more robust long- term randomized controlled trials on more patients, maybe with higher doses of zinc sulfate, are needed to fully establish the efficacy of oral zinc in management of vitiligo.Trial Registration: chiCTRTRC10000930Keywordsvitiligo, zinc, corticosteroid, treatment (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4659428 Wed, 30 Mar 2011 23:00:00 +0100 4659428 http://www.medworm.com/index.php?rid=4644679&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F6 Background: The current study utilized a Bleomycin-induced model of skin fibrosis to investigate the neo-epitope CO3-610 (KNGETGPQGP), a fragment of collagen III released during matrix metalloproteinase-9 (MMP9) degradation of the protein, we have previously described as a novel biomarker for liver fibrosis. The aim was to investigate CO3-610 levels in another well characterised model of fibrosis, to better describe the biomarker in relation to additional fibrotic pathologies. Methods: Skin fibrosis was induced by daily injections of Bleomycin to a total of 52 female C3H mice, while control mice (n=28) were treated with phosphate buffered saline (PBS), for 2, 4, 6 or 8 weeks. Skin fibrosis was evaluated using Visiopharm software on Sirius-red stained skin sections. Urine ELISA assays and c... BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4644679 Mon, 28 Mar 2011 23:00:00 +0100 4644679 http://www.medworm.com/index.php?rid=4525471&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F5 Conclusions: Our studies consolidate the properties of lentiviral vectors as a tool for potent gene delivery and for evaluation of mRNA targets for anti-inflammatory therapy. However, in contrast to local anti-TNFalpha treatment, the therapeutic potential of targeting IL-12B at the RNA level in psoriasis is questioned. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4525471 Sun, 27 Feb 2011 00:00:00 +0100 4525471 http://www.medworm.com/index.php?rid=4478465&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F4 Conclusion: The two cases suggest that the atrophy and blisters may be the uncommon manifestations of amyloidosis cutis dyschromica. It alerts clinicians to consider the possibility of ACD when meeting patients with cutaneous dyschromia. Skin biopsy is essential and family consultation of genetic investigation is very important in such cases. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4478465 Tue, 15 Feb 2011 00:00:00 +0100 4478465 http://www.medworm.com/index.php?rid=4400930&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F3 Conclusions: Cutaneous M. haemophilum infections most often result from HIV or transplantation-associated immunosuppression. Rarely, M. haemophilum may also infect healthy patients or iatrogenically immunosuppressed patients without transplantation. M. kansasii is one of the most frequent NTM and large awareness exists about its involvement in human diseases. Mycobacterial diagnosis of cutaneous infections should be considered in long-lasting skin lesions. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4400930 Wed, 26 Jan 2011 00:00:00 +0100 4400930 http://www.medworm.com/index.php?rid=4319295&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F11%2F1 Conclusions: The fact that a small set of SNPs can predict disease status with average accuracy of 68% makes it possible to use SNP data for psoriasis prediction. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4319295 Fri, 07 Jan 2011 00:00:00 +0100 4319295 http://www.medworm.com/index.php?rid=4144976&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F11 Conclusions: Studies using UKWP or ISAAC criteria should include a validation arm, to contribute to the understanding of potential limitations of their use in different contexts and to explore solutions. We list specific recommendations. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4144976 Tue, 09 Nov 2010 00:00:00 +0100 4144976 http://www.medworm.com/index.php?rid=4037691&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F10 Conclusion: We propose that granulocytes pockets transfusions will be beneficial to heal EG especially in severely immunocompromised patients. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=4037691 Wed, 06 Oct 2010 23:00:00 +0100 4037691 http://www.medworm.com/index.php?rid=3999615&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F9 Conclusions: The PCSA could have a useful role in improving primary care management of pigmented skin lesions. Further work is needed to develop and validate the PCSA in other primary care populations and to evaluate the cost-effectiveness of GP management of pigmented lesions using SIAscopy. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3999615 Fri, 24 Sep 2010 23:00:00 +0100 3999615 http://www.medworm.com/index.php?rid=3916796&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F8 We describe the design of a randomised clinical trial to investigate the effects of classification of hand eczema plus individual counselling versus no intervention. The trial includes health-care workers with hand eczema identified from a self-administered questionnaire delivered to 3181 health-care workers in three Danish hospitals. The questionnaire identifies the prevalence of hand eczema, knowledge of skin-protection, and exposures that can lead to hand eczema. At entry, all participants are assessed regarding: disease severity (Hand Eczema Severity Index); self-evaluated disease severity; number of eruptions; quality of life; skin protective behaviour, and knowledge of skin protection. The patients are centrally randomised to intervention versus no intervention 1:1 stratified for hos... BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3916796 Mon, 30 Aug 2010 23:00:00 +0100 3916796 http://www.medworm.com/index.php?rid=3892834&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F7 This study evaluated 100 patients with skin wounds from excision of melanocytic nevi. 50 patients with lesions on the face and 50 patients with lesions on the back, totalizing 200 lesions excised with modified punch. The resulting superficial skin wounds had the same diameter and depth, and second intention healing followed.Patients were followed for 60 days. Student's t-test, Mann Whitney nonparametric test, analysis of variance, LSD test, Shapiro-Wilks test and Fisher test were used to analyze the results, depending on the nature of the variables being studied.Phenytoin showed better therapeutic and cosmetic results, by healing faster, with more intense epithelization in wounds in comparison with cream (control). Phenytoin showed a statistically significant difference regarding the follo... BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3892834 Mon, 23 Aug 2010 23:00:00 +0100 3892834 http://www.medworm.com/index.php?rid=3886740&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F6 This study was a randomised, assessor-blind, comparative, parallel study of 123 subjects with live head lice. The head lice products were applied according to the manufacturer's instructions (the TTO/LO product and the "suffocation" product were applied three times at weekly intervals according to manufacturers instructions (on Day 0, Day 7 and Day 14) and the P/PB product was applied twice according to manufacturers instructions (on Day 0 and Day 7)). The presence or absence of live lice one day following the last treatment was determined. Results: : The percentage of subjects who were louse-free one day after the last treatment with the product containing tea tree oil and lavender oil (41/42; 97.6%) and the head lice "suffocation" product (40/41, 97.6%) was significantly higher compared ... BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3886740 Thu, 19 Aug 2010 23:00:00 +0100 3886740 http://www.medworm.com/index.php?rid=3863153&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F5 Conclusions: Although SPT is still considered as a valuable diagnostic tool for CM, its low accuracy, sensitivity, and specificity represent the main hamper for the introduction of such a methodology in clinical practice. Dermoscopy remains the best diagnostic tool for the preoperative diagnosis of pigmented skin lesions. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3863153 Thu, 12 Aug 2010 23:00:00 +0100 3863153 http://www.medworm.com/index.php?rid=3697067&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F4 Conclusion: The therapy for CHE patients is currently insufficient. In our long-term model we identified the treatment with alitretinoin as a cost-effective alternative for the therapy of CHE patients in Switzerland. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3697067 Thu, 24 Jun 2010 23:00:00 +0100 3697067 http://www.medworm.com/index.php?rid=3495488&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F3 Conclusions: We found no support for female gender and omega-3 fatty acid supplement as contributing factors in the association between anxiety/depression, and eczema. Somatization and health anxiety accounted for about half of the association between anxiety/depression, and eczema, somatization contributed most. The association between anxiety/depression, and eczema was insignificant after adjustment for somatization and health anxiety. Biological mechanisms underlying the mediating effect of somatization are yet to be revealed. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3495488 Wed, 21 Apr 2010 23:00:00 +0100 3495488 http://www.medworm.com/index.php?rid=3426405&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F2 Conclusion: This unique case report illustrates that different systemic treatments for psoriasis might have implications beyond the care of skin lesions. This insight is especially important in psoriasis patients in view of their deranged hemostatic balance toward a prothrombotic state, which might increase the risk of thrombosis and CVD. Therefore, further studies analyzing the effect of different drugs on platelets physiology are warranted. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3426405 Tue, 30 Mar 2010 23:00:00 +0100 3426405 http://www.medworm.com/index.php?rid=3267977&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F10%2F1 Conclusions: Although this study is small, and based on analysis of existing microarray data, we demonstrate that a treatment response classifier for alefacept can be created based on gene expression of PBMCs in psoriasis. This preliminary study may provide a useful tool to predict response of psoriatic patients to alefacept. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3267977 Fri, 12 Feb 2010 00:00:00 +0100 3267977 http://www.medworm.com/index.php?rid=3086142&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F12 Conclusions: The two-phase dimeticone compound NYDA(R) sensitiv is highly efficacious. The removal of fragrances as compared to an established dimeticone product did not affect in vitro efficacy. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=3086142 Mon, 14 Dec 2009 00:00:00 +0100 3086142 http://www.medworm.com/index.php?rid=2982580&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F11 Conclusions: Dermatologists' treatment of AA is inconsistent. A stronger evidence base will provide more consistent treatment options. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2982580 Thu, 12 Nov 2009 00:00:00 +0100 2982580 http://www.medworm.com/index.php?rid=2896211&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F10 Conclusion: Professional medical use of the internet is widespread among dermatologists in Saudi Arabia. Providing access to the internet in the workplace and training of dermatologists to perform effective electronic searches are badly needed to improve the professional medical use of internet, which is expected to lead to better delivery of patient care. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2896211 Thu, 15 Oct 2009 23:00:00 +0100 2896211 http://www.medworm.com/index.php?rid=2739059&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F9 Background: Facial volume loss contributes significantly to facial aging. The 20-mg/mL hyaluronic acid (HA) formulation used in this study is a smooth, highly cohesive, viscous, fully reversible, volumizing filler indicated to restore facial volume. This first prospective study evaluated use in current aesthetic clinical practice. Methods: A pan-European evaluation conducted under guidelines of the World Association of Opinion and Marketing Research, the trial comprised a baseline visit (visit 1) and a follow-up (visit 2) at 14 +/- 7 days posttreatment. Physicians photographed patients at each visit. Each patient was treated with the 20-mg/mL HA volumizing filler as supplied in standard packaging. Procedural details, aesthetic outcomes, safety, and physician and patient ratings of their ex... BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2739059 Wed, 26 Aug 2009 23:00:00 +0100 2739059 http://www.medworm.com/index.php?rid=2646909&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F8 Conclusions: Familial keloids most commonly manifest autosomal dominant or semidominant inheritance, and there may be familial patterns of keloid distribution. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2646909 Mon, 27 Jul 2009 23:00:00 +0100 2646909 http://www.medworm.com/index.php?rid=2627897&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F7 Conclusions: Our findings further suggest that EGF +61A>G polymorphism may have a limited impact on predisposition and/or pathogenesis of melanoma and its prevalence may vary in different populations. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2627897 Tue, 21 Jul 2009 23:00:00 +0100 2627897 http://www.medworm.com/index.php?rid=2679842&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2Fbmcdermatol%2F Conclusions: This analysis indicates that tanning bed use is common in Germany. The positive relationships of appearance and health based motives with tanning bed use are of great concern. The results indicate underlying misconceptions about the positive effect of artificial UV radiation compared to natural UV radiation particular for high-frequency tanners. The data shows the importance as well as the limitations for risk communication in its current effort to inform effectively about the dangers of artificial UV radiation. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2679842 Sun, 19 Jul 2009 23:00:00 +0100 2679842 http://www.medworm.com/index.php?rid=2443622&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F5 Background: The influence of streptococcal infections in the pathogenesis of psoriasis is not yet understood. However, in vitro data suggest that streptococcal factors influence T-cell function in psoriasis in a HLA-dependent manner. However, studies designed to measure the HLA-C/Streptococci interaction are lacking. In the present study, we hypothesized that there is a statistical interaction between the result of streptococcal throat cultures and the presence of the HLA-Cw0602 allele in psoriasis patients. Methods: We performed a case control study using the "Stockholm Psoriasis Cohort" consisting of patients consecutively recruited within 12 months of disease onset(Plaque psoriasis=439, Guttate psoriasis=143), matched to healthy controls (n=454) randomly chosen from the Swedish Populati... BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2443622 Fri, 29 May 2009 04:00:00 +0100 2443622 http://www.medworm.com/index.php?rid=2366056&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F4 Conclusion: Bathing pruritus is a common finding among young adult Nigerians in the general population. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2366056 Fri, 17 Apr 2009 04:00:00 +0100 2366056 http://www.medworm.com/index.php?rid=2332496&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F4 Conclusions: Bathing pruritus is a common finding among young adult Nigerians in the general population. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2332496 Fri, 17 Apr 2009 04:00:00 +0100 2332496 http://www.medworm.com/index.php?rid=2306666&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F3 Conclusion: Penciclovir 1% cream has the tendency to facilitate the diffusion of the drug through the stratum corneum into the deeper epidermis layers, in which it could reach the target basal cells at effective therapeutical concentration. The small difference in the surface properties between both molecules might also contribute to favour the passage of penciclovir through the epidermis into the deeper basal cells. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2306666 Thu, 02 Apr 2009 04:00:00 +0100 2306666 http://www.medworm.com/index.php?rid=2306669&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F2 Conclusions: We believe that parameter estimates from a mathematical model may provide a more accurate quantification of wound healing rates, and that similar models should be routinely used to compare the efficacy of various treatments in routine practice and in product registration trials. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2306669 Tue, 31 Mar 2009 04:00:00 +0100 2306669 http://www.medworm.com/index.php?rid=2085837&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F9%2F1 Conclusion: These results suggest a possible association between Bax and Gadd45 in AFX, and may refute any possibility of dysfunction of Gadd45 in terms of gene mutation, at least at exon 4 of the Gadd45 gene. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2085837 Wed, 07 Jan 2009 05:00:00 +0100 2085837 http://www.medworm.com/index.php?rid=2070104&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F8%2F5 Conclusions: During a bloom of L. majuscula there were numerous reports of symptoms that could be attributed to dermotoxins found in L. majuscula. The other four years examined had no L. majuscula blooms and the number of L. majuscula symptoms was much reduced. These cases comprised a high percentage of the cases treated at the first aid station. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=2070104 Tue, 30 Dec 2008 05:00:00 +0100 2070104 http://www.medworm.com/index.php?rid=1904530&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F8%2F4 Conclusion: The RTS questionnaire showed a sufficient internal consistency. There is a good convergent validity between the RTS-score and the Fritzpatrick classification avoiding shortcomings of the prevailing standard. The questionnaire represents a simple, reliable and valid instrument for the assessment of sun sensitivity. It can be used in epidemiological studies as well as in skin cancer prevention programs. Further development and standardization of sun sensitivity assessments is necessary to strengthen the evidence of epidemiological studies on causal factors of melanoma and other skin cancers. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=1904530 Fri, 24 Oct 2008 04:00:00 +0100 1904530 http://www.medworm.com/index.php?rid=1732265&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F8%2F3 Conclusion: Existence of lentigines and melanocytic nevi increases chance of having melasma (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=1732265 Tue, 05 Aug 2008 04:00:00 +0100 1732265 http://www.medworm.com/index.php?rid=1678417&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F8%2F3 Background: Very little is known about possible association of nevi and melasma. The study objective was to determine if there is an association between melasma and existence of different kinds of nevi. Methods: In a case-control study, 120 female melasma patients referred to dermatology clinic of Ardabil and 120 patients referred to other specialty clinics who lacked melasma were enrolled after matching for age. Number of different types of nevi including lentigines and melanocytic nevi were compared between case and control group patients. Data were entered into the computer and analyzed by SPSS 13 statistical software. Results: Mean number of lentigines was 25.5 in melasma group compared to 8 in control group(P (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=1678417 Tue, 05 Aug 2008 04:00:00 +0100 1678417 http://www.medworm.com/index.php?rid=1462402&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F8%2F2 Conclusions: Reports investigating the efficacy of NHPs for vitiligo exist, but are of poor methodological quality and contain significant reporting flaws. L-phenylalanine used with phototherapy, and oral Ginkgo biloba as monotherapy show promise and warrant further investigation. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=1462402 Thu, 22 May 2008 04:00:00 +0100 1462402 http://www.medworm.com/index.php?rid=1183764&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F8%2F1 Conclusions: Topical rapamycin inhibits TSC-related tumor growth. These findings could lead to a novel treatment approach for facial angiofibromas and other TSC skin lesions. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=1183764 Mon, 28 Jan 2008 05:00:00 +0100 1183764 http://www.medworm.com/index.php?rid=1061660&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F7%2F6 Conclusions: The present manuscript seeks to raise awareness of the existence of Sweha-Reg to stimulate the international collaboration of registries. A synthesis of data from similar registries across several countries is required to approach an inclusive course understanding of HAE. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=1061660 Fri, 30 Nov 2007 05:00:00 +0100 1061660 http://www.medworm.com/index.php?rid=909103&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F7%2F5 Conclusion: We report the first genome-wide linkage study of atopic dermatitis in an Asian population, and novel loci on chromosomes 15q21 and 1q24 linked to atopic dermatitis. Identification of novel causative genes for atopic dermatitis will advance our understanding of the pathogenesis of atopic dermatitis. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=909103 Fri, 28 Sep 2007 04:00:00 +0100 909103 http://www.medworm.com/index.php?rid=704938&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F7%2F4 Conclusions: The study showed that there were significant differences in self-reported skin complaints among ethnic groups. Issues concerning the cultural value of some skin symptoms should be examined further. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=704938 Fri, 29 Jun 2007 04:00:00 +0100 704938 http://www.medworm.com/index.php?rid=474753&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F7%2F3 Conclusion: Variation in the TOLLIP gene may play a role in the pathogenesis of AD. Yet, replication studies in other cohorts and populations are warranted to confirm these association results. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=474753 Fri, 16 Mar 2007 04:00:00 +0100 474753 http://www.medworm.com/index.php?rid=447436&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F7%2F1 Conclusions: The present study shows that several sunscreens are photounstable in the UVA range after UVnat and UVart. There is a need for a standardized method to measure photostability and the photostability should be marked on the sunscreen product. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=447436 Mon, 26 Feb 2007 05:00:00 +0100 447436 http://www.medworm.com/index.php?rid=447435&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F7%2F2 Conclusions. We hypothesize that these papules may represent a unique type of mechanistic inflammatory reaction, seen only in the context of drug-induced CD11a blockade, and not during the natural disease process. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=447435 Mon, 26 Feb 2007 05:00:00 +0100 447435 http://www.medworm.com/index.php?rid=310266&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F10 Conclusions: Our mathematical model identifies key aspects of technique that may contribute to error. To keep the inherent error rate at a minimum, we advocate minimal division and minimal physical thickness of Mohs specimens. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=310266 Wed, 06 Dec 2006 07:00:00 +0100 310266 http://www.medworm.com/index.php?rid=447437&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F10 Conclusion: Our mathematical model identifies key aspects of technique that may contribute to error. To keep the inherent error rate at a minimum, we advocate minimal division and minimal physical thickness of Mohs specimens. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=447437 Wed, 06 Dec 2006 05:00:00 +0100 447437 http://www.medworm.com/index.php?rid=250660&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F9 Conclusions: Inflammatory recurrence after discontinuation of efalizumab therapy is a manageable event, with a number of therapies and approaches available to physicians, including short courses of cyclosporin or methotrexate. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=250660 Thu, 26 Oct 2006 06:00:00 +0100 250660 http://www.medworm.com/index.php?rid=197768&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F8 Conclusions: Efalizumab was shown to have a favorable benefit:risk profile using the comprehensive outcome measure SPC. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=197768 Tue, 19 Sep 2006 06:00:00 +0100 197768 http://www.medworm.com/index.php?rid=22504&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F7 Conclusion: Radiotherapy for keloids represents a safe and effective option for post-surgical keloid therapy, especially for patients with bulky or recurrent disease. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22504 Wed, 19 Apr 2006 06:00:00 +0100 22504 http://www.medworm.com/index.php?rid=88865&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F6 Conclusion: This preliminary clinical study demonstrates that hypersensitivity reactions to cyanobacteria appear to be infrequent in both the general and dermatological outpatient populations. As cyanobacteria are widely distributed in aquatic environments, a better appreciation of risk factors, particularly with respect to allergic predisposition, may help to refine health advice given to people engaging in recreational activities where nuisance cyanobacteria are a problem. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=88865 Tue, 04 Apr 2006 06:00:00 +0100 88865 http://www.medworm.com/index.php?rid=22505&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F6 Conclusions: This preliminary clinical study demonstrates that hypersensitivity reactions to cyanobacteria appear to be infrequent in both the general and dermatological outpatient populations. As cyanobacteria are widely distributed in aquatic environments, a better appreciation of risk factors, particularly with respect to allergic predisposition, may help to refine health advice given to people engaging in recreational activities where nuisance cyanobacteria are a problem. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22505 Tue, 04 Apr 2006 06:00:00 +0100 22505 http://www.medworm.com/index.php?rid=145785&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F5 Conclusion: The irritant properties and cutaneous sensitising potential of cylindrospermopsin indicate that these toxicological endpoints should be considered by public health advisors and reservoir managers when setting guidelines for recreational exposure to cyanobacteria. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=145785 Fri, 31 Mar 2006 07:00:00 +0100 145785 http://www.medworm.com/index.php?rid=22506&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F5 Conclusions: The irritant properties and cutaneous sensitising potential of cylindrospermopsin indicate that these toxicological endpoints should be considered by public health advisors and reservoir managers when setting guidelines for recreational exposure to cyanobacteria. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22506 Fri, 31 Mar 2006 07:00:00 +0100 22506 http://www.medworm.com/index.php?rid=22507&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F4 Conclusion: The overall incidence rate of all skin diseases combined in general practice decreased whereas the incidence rates of bacterial, mycotic and atopic skin diseases increased. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22507 Tue, 21 Mar 2006 07:00:00 +0100 22507 http://www.medworm.com/index.php?rid=22508&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F3 Conclusion: According to our study, anti-TPO was shown to be significantly more common in vitiligo patients especially in young women, compared with control group. As this antibody is a relatively sensitive and specific marker of autoimmune thyroid disorders including Hashimoto thyroiditis and Graves' disease, and considering the fact that vitiligo usually precedes the onset of thyroid dysfunction, periodic follow-up of vitiligo patients for detecting thyroid diseases is further emphasized especially in young women with increased level of anti-TPO. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22508 Fri, 10 Mar 2006 07:00:00 +0100 22508 http://www.medworm.com/index.php?rid=22509&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F2 Conclusion: Constipation is a common clinical feature of RDEB, but fetal complications of chronic constipation are rarely reported. To the author's best knowledge, it has not been reported or recognized in the English literature previously. The aggressive assessment of constipation with fecal impaction is recommended in patients with RDEB. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22509 Wed, 15 Feb 2006 07:00:00 +0100 22509 http://www.medworm.com/index.php?rid=22510&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F6%2F1 Conclusion: Repetitive and frequent hand washing increases skin dryness and roughness. Use of a hand cream immediately after each hand wash can confine both skin dryness and skin roughness. Regular use of skin care preparations should therefore help to prevent both dry and rough skin among healthcare workers in clinical practice. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22510 Mon, 13 Feb 2006 07:00:00 +0100 22510 http://www.medworm.com/index.php?rid=22511&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F5%2F13 Conclusion: A 12-week course of efalizumab improved HRQOL and other patient-reported outcomes in patients with moderate to severe plaque psoriasis. The benefits of efalizumab therapy in High-Need patients were similar to those observed in the total study population, indicating that the beneficial impact of efalizumab on QOL is consistent regardless of disease severity, prior therapy, or contraindications to previous therapies. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22511 Fri, 16 Dec 2005 07:00:00 +0100 22511 http://www.medworm.com/index.php?rid=22512&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F5%2F12 Conclusion: We conclude that methotrexate therapy is relatively safe in patients with genetic hemochromatosis, with no other risk factor, but caution that the risk of fibrosis be monitored, preferably by non-invasive techniques, or by liver biopsy. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22512 Tue, 29 Nov 2005 07:00:00 +0100 22512 http://www.medworm.com/index.php?rid=22513&cid=s_31726_12_f&fid=31726&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-5945%2F5%2F11 Conclusion: The incidence of positive auto-immune antibodies in Iranian patients is higher than previous reports. Concerning the female:male ratio, thyroid function tests and the prevalence of alopecia in first-degree relatives, our results are compatible with previous data obtained from different ethnic populations. Previous reports documented that a greater severity and longer duration of AA were seen in the early onset forms; however our result are relatively different which could be explained by differences in genetic factors. (Source: BMC Dermatology) BMC Dermatology journals http://www.medworm.com/rss/comments.php?id=22513 Mon, 31 Oct 2005 07:00:00 +0100 22513