MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'BMC Musculoskeletal Disorders' source. Thu, 09 Feb 2012 00:02:24 +0100 http://www.medworm.com/index.php?rid=5669124&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F13 Conclusions: It is concluded that a child had increased sensitivity at the tendon attachment site and the muscle belly (endplate zone) after age of 4 years. Therefore, it is likely that a child may develop an A-Trp and a latent MTrP at the brachioradialis muscle after the age of 4 years. The changes in sensitivity, or the development for these trigger points, may not be related to the activity level of children aged 7-11 years. Further investigation is still required to indentify the exact timing of the initial occurrence of a-Trps and latent MTrPs.Key words: myofascial trigger points, children, pressure pain threshold, algometry (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5669124 Wed, 08 Feb 2012 05:00:00 +0100 5669124 http://www.medworm.com/index.php?rid=5669126&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F11 DiscussionThis trial protocol proposes a rigorous and potentially significant evaluation of a simple and readily provided therapeutic approach which, if effective, could be of a great benefit for this group of patients.Trial registrationCurrent Controlled Trials: ISRCTN02824122 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5669126 Mon, 06 Feb 2012 05:00:00 +0100 5669126 http://www.medworm.com/index.php?rid=5669125&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F12 Conclusions: Ex-elite table tennis players were found to have increased levels of radiological signs of OA in the knee joint though this did not transpire through to altered levels of physical disability or knee stiffness in these players when compared with subjects from the general population suggesting that function in these players is not severely impacted upon. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5669125 Mon, 06 Feb 2012 05:00:00 +0100 5669125 http://www.medworm.com/index.php?rid=5650899&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F10 This study is a double-blind (participants and evaluators blinded) randomised clinical trial that will allow the comparison of patients with a cervical radiculopathy randomly assigned to one of two groups: one group will receive a 4-week rehabilitation program targeting the opening of intervertebral foramen, and the second group will receive a 4-week conventional rehabilitation program. Thirty-six subjects with cervical radiculopathy will be recruited from participating medical and physiotherapy clinics and will be evaluated at baseline, at the end of the 4-week program and four weeks following the end of the program. The primary outcome measure will be the validated Neck Disability Index questionnaire. Secondary outcome measures will include the short version of the Disabilities of the Ar... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5650899 Tue, 31 Jan 2012 05:00:00 +0100 5650899 http://www.medworm.com/index.php?rid=5639761&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F9 This study is a single blind pragmatic cluster randomised controlled trial. Four upper secondary schools have been invited to participate in the study (approximately 2500 students, aged 15-19 years). Students are asked to answer an online questionnaire regarding musculoskeletal pain. The students who report knee pain are contacted by telephone and offered a clinical examination by a rheumatologist. Subjects who fit the inclusion criteria and are diagnosed with PFPS are invited to participate in the study. A minimum of 102 students with PFPS are then cluster-randomised into two intervention groups based on which school they attend. Both intervention groups receive written information and education. In addition to patient education, one group receives multimodal physiotherapy consisting prim... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5639761 Fri, 27 Jan 2012 05:00:00 +0100 5639761 http://www.medworm.com/index.php?rid=5630882&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F8 Conclusions: In an experimental setting, the newly developed guided freehand technique for distal interlocking has proven to markedly reduce radiation exposure when compared to the conventional freehand technique. The method utilizes established clinical workflows and does not require cost intensive add-on devices or extensive training. The underlying principle carries potential to assist implant positioning in numerous other applications within orthopedics and trauma from screw insertions to placement of plates, nails or prostheses. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5630882 Wed, 25 Jan 2012 05:00:00 +0100 5630882 http://www.medworm.com/index.php?rid=5630883&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F7 This study uses a case-crossover design. One thousand adults with a sudden onset of low back pain presenting to primary care clinicians will be recruited. Basic demographic and clinical information including exposure to putative triggers will be collected using a questionnaire. These triggers include exposure to hazardous manual tasks, physical activity, a slip/trip or fall, consumption of alcohol, sexual activity, being distracted, and being fatigued or tired. Exposures in the case window (0-2 hours from the time when participants first notice their back pain) will be compared to exposures in two control time-windows (one 24-26 hours and another 48-50 hours before the case window).DiscussionThe completion of this study will provide the first-research based estimates of the increase in ris... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5630883 Tue, 24 Jan 2012 05:00:00 +0100 5630883 http://www.medworm.com/index.php?rid=5621533&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F5 Conclusions: LBP rehabilitation can be improved by addressing the following points. Early management of LBP should be activity-centred instead of pain-centred. It is mandatory to implement return to work management early, including return to adapted work, to improve rehabilitation for patients. Rehabilitation has to start when patients have been off work for three months. Using interpreters more frequently would improve communication between health professionals and patients, and reduce misunderstandings about treatment procedures. Special emphasis must be put on the process of goal-formulation by spending more time with patients in order to identify barriers to goal attainment. Information on the return to work process should also include the financial aspects of unemployment and disabili... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5621533 Mon, 23 Jan 2012 05:00:00 +0100 5621533 http://www.medworm.com/index.php?rid=5621532&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F6 Conclusions: We conclude that the classification tested in this study is reliable and reproducible when applied by raters experienced in fracture management. The reliability varies according to the experience of the raters. Experienced raters can verify the classification, and avoid unnecessary follow-up appointments. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5621532 Mon, 23 Jan 2012 05:00:00 +0100 5621532 http://www.medworm.com/index.php?rid=5611823&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F4 DiscussionThis prospective clinical observational cohort will combine self-reported data, comprehensive clinical and MRI assessment, together with qualitative enquiries, to describe the course, health care usage, patients' experiences and prognostic indicators in an adult population presenting in primary care with LBP and leg pain with or without nerve root involvement. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5611823 Fri, 20 Jan 2012 05:00:00 +0100 5611823 http://www.medworm.com/index.php?rid=5599797&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F3 Conclusions: The prevalence of vertebral fractures increased by age in women and men, but the overall prevalence was lower than expected, considering the high prevalence of hip and forearm fractures in Norway. In both sexes, the wedge type was the fracture type most frequently observed and most common in the thoracic region. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5599797 Tue, 17 Jan 2012 05:00:00 +0100 5599797 http://www.medworm.com/index.php?rid=5599798&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F2 Background: Low bone mineral density (BMD) and falls are common problems encountered in the postmenopausal women. The purpose was to evaluated the association between postural balance and BMD in postmenopausal women and its relation to risk for falls. Methods: In this cross-sectional study, 225 women in amenorrhea >12 months and age >/= 45 years were included and divided, according to BMD, in T-score values > -2.0 SD (n=140) and (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5599798 Mon, 16 Jan 2012 05:00:00 +0100 5599798 http://www.medworm.com/index.php?rid=5585389&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F13%2F1 Conclusions: The intermediate factors contributed differently to work ability in the two professions. Self-efficacy, personal safety and musculoskeletal wellbeing were important for the assistant nurses, while the work ability of the care aides was associated with the safety climate, but also with the non-changeable factors age and seniority. All these factors are important to acknowledge in practice and in further research. Proactive workplace interventions need to focus on potentially modifiable factors such as self-efficacy, safety climate, physical job demands and musculoskeletal wellbeing. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5585389 Wed, 11 Jan 2012 05:00:00 +0100 5585389 http://www.medworm.com/index.php?rid=5553657&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F291 Conclusion: The Rottometer was a reliable measurement instrument concerning knee rotation at the three different flexion angles (90degrees, 60degrees and 30degrees) with 6 and 9 Nm applied torques as well as the examiner's apprehension of end-feel. Three Nm was not a reliable torque. The most reliable measurements were made at 9 Nm applied torque. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5553657 Fri, 30 Dec 2011 05:00:00 +0100 5553657 http://www.medworm.com/index.php?rid=5553656&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F292 Conclusions: Piroxicam improves clinically relevant measures of muscle performance and mobility in geriatric patients hospitalized with acute infection-induced inflammation. Underlying mechanisms may include modifications in the cytokine network and increases in monocytic expression of cytoprotective Hsp27.Trial registrationCurrent Controlled Trials (ISRCTN58517443) http://www.controlled-trials.com/ISRCTN58517443/ (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5553656 Fri, 30 Dec 2011 05:00:00 +0100 5553656 http://www.medworm.com/index.php?rid=5545966&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F290 DiscussionThis trial will help to determine, whether transcranial direct current stimulation is an effective treatment for patients with chronic low back pain and whether it can further enhance the effects of a cognitive behavioural pain management programme. Trial registration: Current Controlled Trials ISRCTN89874874. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5545966 Wed, 28 Dec 2011 05:00:00 +0100 5545966 http://www.medworm.com/index.php?rid=5539617&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F289 Conclusion: The overwhelming majority of patients preferred THA to HA for the treatment of a displaced femoral neck fracture when confronted with risks and outcomes of both procedures on a decision board. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5539617 Fri, 23 Dec 2011 05:00:00 +0100 5539617 http://www.medworm.com/index.php?rid=5527582&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F288 Conclusions: These data document for the first time that muscle cells can play a significant secondary role in bone repair and this knowledge may lead to important translational applications in orthopaedic surgery.Please see related article: http://www.biomedcentral.com/1741-7015/9/136 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5527582 Thu, 22 Dec 2011 05:00:00 +0100 5527582 http://www.medworm.com/index.php?rid=5527584&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F286 Conclusion: Both augmentation pedicle screw with Polymethylmethacrylate (PMMA) and autogenous bone treating degenerative lumbar scoliosis combined with osteoporosis can achieve a good surgical result. Less oral pain medicines taken are the potential benefits of Polymethylmethacrylate augmentation, but that is at the cost of more medical spending. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5527584 Wed, 21 Dec 2011 05:00:00 +0100 5527584 http://www.medworm.com/index.php?rid=5527583&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F287 Conclusions: Sixty percent of the resources allocated by the SNHSCI to fund physical treatment for NP, BP and SP in private practices are spent on forms of treatment proven to be ineffective, or for which there is no evidence of effectiveness. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5527583 Wed, 21 Dec 2011 05:00:00 +0100 5527583 http://www.medworm.com/index.php?rid=5516550&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F285 Conclusion: The linear association between the number of non-musculoskeletal and musculoskeletal symptoms might indicate that the symptoms share common characteristics and even common underlying causal factors. The total burden of symptoms as determined by the number of symptoms reported might be an interesting generic indicator of health and well-being, as well as present and future functioning. Research on symptom reporting might also be an alternative pathway to describe and, possibly, understand the medically unexplained multisymptom conditions. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5516550 Sun, 18 Dec 2011 05:00:00 +0100 5516550 http://www.medworm.com/index.php?rid=5516551&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F284 Conclusions: The surveillance programme reduced the number of hip dislocations and the proportion of children undergoing hip surgery was lower. However, with the surveillance programme the first operation was performed at a younger age. Our results strongly support the effectiveness of a specifically designed follow-up programme for the prevention of hip dislocation in children with CP. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5516551 Fri, 16 Dec 2011 05:00:00 +0100 5516551 http://www.medworm.com/index.php?rid=5507202&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F283 Conclusion: The protective effect of the mtDNA haplogroup J in the OA disease arise from a lower oxidative stress in carriers of this haplogroup, since this haplogroup is related to lower NO production and hence longer telomere length of PBLs too. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5507202 Thu, 15 Dec 2011 05:00:00 +0100 5507202 http://www.medworm.com/index.php?rid=5507203&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F282 DiscussionBy relating anatomic properties, kinematics and muscle dynamics to subacromial volume, we expect to identify one or more predominant pathophysiological mechanisms in every SIS patient. These differences in underlying mechanisms are a reflection of the variations in symptoms, clinical scores and outcomes reported in literature. More insight in these mechanisms is necessary in order to optimize future diagnostic and treatment strategies for patients with SIS symptoms.Trial Registration: Dutch Trial Registry (Nederlands Trial Register) NTR2283 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5507203 Wed, 14 Dec 2011 05:00:00 +0100 5507203 http://www.medworm.com/index.php?rid=5496646&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F281 Conclusions: Our results suggest satisfying overall long-term outcome for the surgical treatment of UBC, although short- and mid-term observation show a considerable rate of recurrence independent of the surgical technique. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5496646 Tue, 13 Dec 2011 05:00:00 +0100 5496646 http://www.medworm.com/index.php?rid=5496648&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F279 Conclusions: Our results suggest that FTY720 may enhance cartilage degradation in pro-inflammatory environment. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5496648 Mon, 12 Dec 2011 05:00:00 +0100 5496648 http://www.medworm.com/index.php?rid=5496647&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F280 Background: Recent international guidelines recommend intra-articular corticosteroid injections for patients with hip osteoarthritis who have moderate to severe pain and do not respond satisfactorily to oral analgesic/anti-inflammatory agents. Of the five available randomized controlled trials, four showed positive effects with respect to pain reduction. However, intra-articular injection in the hip is complex because the joint is adjacent to important neurovascular structures and cannot be palpated. Therefore fluoroscopic or ultrasound guidance is needed.The systemic effect of corticosteroids has been studied in patients with impingement shoulder pain. Gluteal corticosteroid injection was almost as effective as ultrasound-guided subacromial corticosteroid injection. Such a clinically rele... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5496647 Mon, 12 Dec 2011 05:00:00 +0100 5496647 http://www.medworm.com/index.php?rid=5478561&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F278 Conclusions: Registration of orthopaedic trauma trials does not consistently result in publication. When trials are registered, many do not cite NCT ID in the publication. Furthermore, changes that are not reflected in the registry of the trial are frequently made to the final publication. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5478561 Wed, 07 Dec 2011 05:00:00 +0100 5478561 http://www.medworm.com/index.php?rid=5478562&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F276 DiscussionThe findings will help determine whether neuromuscular exercise is superior to traditional quadriceps strengthening regarding effects on knee load, pain and physical function in people with medial knee osteoarthritis and varus malalignment.Trial Registration:Australian New Zealand Clinical Trials Registry reference: ACTRN12610000660088 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5478562 Mon, 05 Dec 2011 05:00:00 +0100 5478562 http://www.medworm.com/index.php?rid=5470540&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F274 The objective is to present the design of a randomised controlled trial (RCT) aimed at evaluating the effectiveness of a combined individual physical and cognitive behavioural-graded activity program on self-reported general physical function, in addition to neck function, pain, disability and quality of life in patients with chronic neck pain following whiplash injury compared with a matched control group measured at baseline and 4 and 12 months after baseline. Methods: The design is a two-centre, RCT-study with a parallel group design. Included are whiplash patients with chronic neck pain for more than 6 months, recruited from physiotherapy clinics and an out-patient hospital department in Denmark. Patients will be randomised to either a pain management (control) group or a combined pain... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5470540 Fri, 02 Dec 2011 05:00:00 +0100 5470540 http://www.medworm.com/index.php?rid=5470539&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F275 Conclusions: Despite higher preoperative leg pain levels, outcomes in lumbar TDR patients with HNP and radiculopathy were similar to outcomes in patients with the classic indication; this because patients with higher preoperative leg pain levels benefit from a relatively greater leg pain alleviation. The group with absence of HNP but presence of radiculopathy showed considerably less benefits from the operation, which is probably related to ongoing degenerative processes of the posterior segmental structures. This observational multicenter study suggests that the diagnoses HNP and radiculopathy, combined or alone, may not have to be considered as absolute or relative contraindications for mono-segmental lumbar TDR anymore, whereas patients without HNP but with radiculopathy seem to be subo... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5470539 Fri, 02 Dec 2011 05:00:00 +0100 5470539 http://www.medworm.com/index.php?rid=5460229&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F273 Conclusions: The biochemical differences that existed between knees with and without effusion provide support that OA subsets may exist, characterized by distinct biochemical characteristics and clinical findings (e.g., effusion). (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5460229 Mon, 28 Nov 2011 05:00:00 +0100 5460229 http://www.medworm.com/index.php?rid=5450732&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F272 Conclusions: There was little evidence of agreement on the use of several core data collection instruments, in particular on the measurement of OA. The heterogeneity of OA definitions hampers comparing prevalence rates of OA, but other research questions can be investigated using high quality harmonized data. By publishing the harmonization guidelines, insight is given into (the interpretation of) all post harmonized data of the EPOSA study. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5450732 Mon, 28 Nov 2011 05:00:00 +0100 5450732 http://www.medworm.com/index.php?rid=5443521&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F267 Conclusions: Hand dominance could have an influence on the scapular kinematics, which should be taken into consideration when describing and comparing neuromuscular characteristics in individuals with chronic neck pain. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443521 Thu, 24 Nov 2011 05:00:00 +0100 5443521 http://www.medworm.com/index.php?rid=5443520&cid=s_29524_31_f&fid=29524&url=%24%7Bitem.link%7D Conclusions: Our findings revealed pressure pain hypersensitivity over distant non-symptomatic distant points but not over the symptomatic areas in pianists suffering from neck pain. In addition, pianists with neck pain also had smaller hand size than those without neck pain. Future studies are not needed to further determine the relevance of these findings in the clinical course of neck pain as playing-related musculoskeletal disorder in professional pianists. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443520 Thu, 24 Nov 2011 05:00:00 +0100 5443520 http://www.medworm.com/index.php?rid=5443519&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F269 Conclusion: Low vitality predicts deterioration of limitations in activities in elderly patients with osteoarthritis of the knee, in addition to established somatic and cognitive risk factors. However, the contribution of vitality is relatively small. Results of this study are relevant for the group of patients with knee or hip OA, attending hospitals and rehabilitation centers. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443519 Thu, 24 Nov 2011 05:00:00 +0100 5443519 http://www.medworm.com/index.php?rid=5443518&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F270 DiscussionResults from this trial will contribute to the evidence regarding the effect of a hip-specific exercise regime on physical function, pain, and health-related quality of life in patients with hip osteoarthritis.Trial registration: German Clinical Trial Register DRKS00000651. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443518 Thu, 24 Nov 2011 05:00:00 +0100 5443518 http://www.medworm.com/index.php?rid=5443517&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F271 Conclusions: The changes after pinealectomy in sheep are indicative of bone loss. Overall, these findings suggest that the pineal gland may influence bone metabolism and that pinealectomy can be used to induce bone loss in sheep. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443517 Thu, 24 Nov 2011 05:00:00 +0100 5443517 http://www.medworm.com/index.php?rid=5443523&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F265 DiscussionThis trial is expected to deliver results in early 2013.Trial Registration: ISRCTN34863373UKCRN portfolio ID 6847 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443523 Wed, 23 Nov 2011 05:00:00 +0100 5443523 http://www.medworm.com/index.php?rid=5443522&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F266 This study aimed to establish the profile and the evolution of an early Rheumatoid arthritis (RA) cohort in the Moroccan population and also to search possible predictor factors of structural progression. Methods: Patients with early RA ( (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443522 Wed, 23 Nov 2011 05:00:00 +0100 5443522 http://www.medworm.com/index.php?rid=5443524&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F264 Background: Oxidative stress play a main role in the initiation and progression of the OA disease and leads to the degeneration of mitochondria. To prevent this, the chondrocytes possess a well-coordinated enzymatic antioxidant system. Besides, the mitochondrial DNA (mtDNA) haplogroups are associated with the OA disease. Thus, the main goal of this work is to assess the incidence of the mtDNA haplogroups on serum levels of two of the main antioxidant enzymes, Manganese Superoxide Dismutase (Mn-SOD or SOD2) and catalase, and to test the suitability of these two proteins for potential OA-related biomarkers. Methods: We analyzed the serum levels of SOD2 and catalase in 73 OA patients and 77 healthy controls carrying the haplogroups J, U and H, by ELISA assay. Knee and hip radiographs were cla... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5443524 Tue, 22 Nov 2011 05:00:00 +0100 5443524 http://www.medworm.com/index.php?rid=5433374&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F262 Conclusions: This study has demonstrated that anemia at admission and postoperative anemia needing an ABT (PANT) were independent risk factors for worse outcome in hip fracture patients. In multivariable regression analysis, anemia as such had no effect on mortality, due to a rescue effect of PANT. In-hospital, 3- and 12-month mortality was negatively affected by PANT, with the main effect in the first 3 months postoperatively. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5433374 Mon, 21 Nov 2011 05:00:00 +0100 5433374 http://www.medworm.com/index.php?rid=5433373&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F263 Background: Enhancing osteogenic capabilities of bone matrix for the treatment of fractures and segmental defects using growth factors is an active area of research. Recently, synthetic peptides like AC- 100, TP508 or p-15 corresponding to biologically active sequences of matrix proteins have been proven to stimulate bone formation. The platelet-derived growth factor (PDGF) BB has been identified as an important paracrine factor in early bone healing. We hypothesized that the combined use of PDGF-BB with synthetic peptides could result in an increase in proliferation and calcification of osteoblast-like cells. Methods: Osteoblast-like cell cultures were treated with PDGF and synthetic peptides, singly and as combinations, and compared to non-treated control cell cultures. The cultures were... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5433373 Mon, 21 Nov 2011 05:00:00 +0100 5433373 http://www.medworm.com/index.php?rid=5424173&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F261 Background: This multicenter, open-label, prospective, single cohort study evaluated the effectiveness and safety of adalimumab in a clinical setting reflecting the Canadian standard of care for the treatment of patients with rheumatoid arthritis (RA). Methods: Patients (greater than or equal to)18 years of age with a history of active RA (greater than or equal to)3 months and fulfilling Canadian requirements for biological therapy received adalimumab 40 mg subcutaneously every other week for 12 weeks. Pre-study DMARD treatment regimens, corticosteroids, or NSAIDs were allowed throughout the study. The primary effectiveness outcome measure was the mean change in 28-joint disease activity score (DAS28) from baseline to Week 12. Secondary measures included the proportion of patients achievin... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5424173 Thu, 17 Nov 2011 05:00:00 +0100 5424173 http://www.medworm.com/index.php?rid=5411325&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F259 Conclusions: Homing was confirmed by the incorporation of injected GFP-labeled MSCs within the repaired newly formed cartilage. Significant recovery proves that the use of IA injection of autologous MSCs is a viable and a practical option for treating different degrees of osteoarthritis.KeywordsMSCs, Chondral defect, Intra-articular, Homing, GFP, Repair, Donkeys. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5411325 Tue, 15 Nov 2011 05:00:00 +0100 5411325 http://www.medworm.com/index.php?rid=5401951&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F257 Conclusion: A MEP has been developed to enhance self-management in patients with OA attending a multidisciplinary OA outpatient clinic. The effectiveness of the MEP followed by individual consultations with members of the multidisciplinary team is currently evaluated in a randomised controlled trial with respect to patient satisfaction and functioning. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5401951 Fri, 11 Nov 2011 05:00:00 +0100 5401951 http://www.medworm.com/index.php?rid=5401950&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F258 Conclusion: Gait analysis may provide additional information in the identification of subgroups among fibromyalgia patients. Gait analysis provided relevant information about physical and cognitive status, and pain behavior. Further studies are needed to better understand gait analysis implications in FM. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5401950 Fri, 11 Nov 2011 05:00:00 +0100 5401950 http://www.medworm.com/index.php?rid=5390689&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F256 DiscussionThis protocol will lead to the generation of unique datasets which will be used to develop linked inverse dynamic and forward dynamic biomechanical foot models. These models may be beneficial in predicting the effect of and thus improving the efficacy of orthotic devices for the foot and ankle. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5390689 Thu, 10 Nov 2011 05:00:00 +0100 5390689 http://www.medworm.com/index.php?rid=5390690&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F255 Conclusion: Since the four different scales derived from BF-BS, A, P, and EF components of the ICF core set for OA were shown to be valid and reliable through a combination of Rasch analysis and classical psychometric methods, these might be used as clinical assessment tools. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5390690 Tue, 08 Nov 2011 05:00:00 +0100 5390690 http://www.medworm.com/index.php?rid=5390691&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F254 Conclusions: In patients with hip fracture (cervical treated with hemiarthroplasty or pertrochanteric or subtrochanteric treated with internal fixation) preoperative use of low-dose acetylsalicylic acid was associated with significantly increased need for postoperative blood transfusions and significantly higher all-cause mortality during one year after surgery. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5390691 Mon, 07 Nov 2011 05:00:00 +0100 5390691 http://www.medworm.com/index.php?rid=5390692&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F253 Conclusions: : In Taiwan, three-quarters of all orthopedic dislocations were of the upper limbs. The most common complex fracture-dislocation was of the knee, followed by the wrist and the ankle. Those usually needed a treatment combined with open reduction of fractures and resulted in a higher direct medical expenditure.Key words: incidence, orthopedic dislocation (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5390692 Sat, 05 Nov 2011 04:00:00 +0100 5390692 http://www.medworm.com/index.php?rid=5366668&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F251 Background: Knee size and body size differ in Asians compared with Caucasians. Nevertheless, many total knee arthroplasty (TKA) prostheses used worldwide are made for Western Caucasian subjects. As a result, an Asian's knee might not fit these prostheses. We studied the Flexible Nichidai Knee (FNK) system, a new model of TKA for Asian patients. The purpose of this report is to investigate the outcomes of this prosthesis retrospectively. Methods: We investigated 1055 primary TKAs in 595 patients who underwent FNK for osteoarthritis (OA) in Japan and were followed for >5 years. The knee score and function score were used for clinical evaluation. We examined the range of motion (ROM) preoperatively and at final follow-up and radiographic assessments. In addition, postoperative complications w... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366668 Wed, 02 Nov 2011 04:00:00 +0100 5366668 http://www.medworm.com/index.php?rid=5366667&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F252 We present the design of a cohort study that aims to determine the course and prognostic factors for recovery in patients with chronic non-specific low back pain. Methods: All participating patients were recruited (Jan 2003-Dec 2008) from the same rehabilitation centre and were evaluated by means of (postal) questionnaires and physical examinations at baseline, during the 2-month therapy program, and at 5 and 12 months after start of therapy. The therapy protocol at the rehabilitation centre used a bio-psychosocial approach to stimulate patients to adopt adequate (movement) behaviour aimed at physical and functional recovery. The program is part of regular care and consists of 16 sessions of 3 hours each, over an 8-week period (in total 48 hours), followed by a 3-month self-management prog... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366667 Wed, 02 Nov 2011 04:00:00 +0100 5366667 http://www.medworm.com/index.php?rid=5366669&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F249 Conclusions: Modified HHD appears to be a reliable strength measure, producing good to excellent ICC values for both inter- and intrarater reliability in a group of TKA patients. High SEM and SDD values, however, indicate high measurement error for individual measures. This study demonstrates that a modified HHD is appropriate to evaluate knee strength changes in TKA patient groups. However, it also demonstrates that modified HHD is not suitable to measure individual strength changes. The use of modified HHD is, therefore, not advised for use in a clinical setting. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366669 Mon, 31 Oct 2011 04:00:00 +0100 5366669 http://www.medworm.com/index.php?rid=5366673&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F245 Conclusions: The pathophysiological role of cytokines in FMS is still unclear. Studies of higher quality and with higher numbers of subjects are needed. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366673 Fri, 28 Oct 2011 04:00:00 +0100 5366673 http://www.medworm.com/index.php?rid=5366672&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F246 Conclusions: The involuntary contraction assay is a reliable system to assess muscle function in rodents and can be applied in preclinical research, including age-related sarcopenia and other myopathy. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366672 Fri, 28 Oct 2011 04:00:00 +0100 5366672 http://www.medworm.com/index.php?rid=5366671&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F247 Conclusions: These data show that rivaroxaban treatment may negatively affect bone through a reduction in osteoblast function. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366671 Fri, 28 Oct 2011 04:00:00 +0100 5366671 http://www.medworm.com/index.php?rid=5366670&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F248 Background: Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus integrity. Methods: Three-dimensional coronal DESSwe MRIs were used to segment and quantitatively measure the size and position of the medial and lateral menisci, and their correlation with sex, height, weight, and tibial plateau area. 102 knees (40 male and 62 female) were drawn from the Osteoarthritis Initiative "non-exposed" reference cohort, including subjects without symptoms, radiographic signs, or risk factors for knee OA. Knees with MRI signs of meniscus lesions were excluded. Results: The tibial plateau area was significantly larger (p (Source: BMC Musculoskeletal Di... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366670 Fri, 28 Oct 2011 04:00:00 +0100 5366670 http://www.medworm.com/index.php?rid=5366674&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F244 Conclusions: For clinical assessment of sensibility touch threshold assessed by monofilaments (WEST) and tactile gnosis measured with the STITM test are the most responsive tests and are recommended for future studies. The use of handheld myometry (RIHM) for manual muscle testing, despite more specifically targeting thenar muscles, was less responsive than grip or tripod pinch testing using the digital grip analyser (MIE). When assessing power and pinch strength the effect of other concomitant conditions such as degenerative joint disease on strength needs to be considered. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5366674 Thu, 27 Oct 2011 04:00:00 +0100 5366674 http://www.medworm.com/index.php?rid=5350267&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F243 Conclusions: Definition C of the MFPDI is more sensitive to age and gender differences in the proportion of people with disabling foot pain, and would therefore seem to be the most appropriate case definition to use in epidemiological studies involving a broad age range of participants. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5350267 Wed, 26 Oct 2011 04:00:00 +0100 5350267 http://www.medworm.com/index.php?rid=5350270&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F240 Conclusion: Long-term use of CsA can weaken the biomechanical properties and thus increase the fracture rate of the lumbar vertebra and the proximal femur. However, CsA therapy has less effect on the middle femur shaft. The effects of CsA on skeleton are site-specific. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5350270 Mon, 24 Oct 2011 04:00:00 +0100 5350270 http://www.medworm.com/index.php?rid=5350269&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F241 DiscussionIn this paper, we describe the protocol of a prospective cohort study in Dutch older adults with joint pain and comorbidity and discuss the potential strengths and limitations of the study. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5350269 Mon, 24 Oct 2011 04:00:00 +0100 5350269 http://www.medworm.com/index.php?rid=5350268&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F242 Background: The aims were to explore bone mineral density (BMD) by digital X-ray radiogrammetry (DXR) in postmenopausal women with long-lasting rheumatoid arthritis (RA) in relation to dual x-ray absorptiometry (DXA)-BMD, joint destruction by conventional radiographs and disease related variables in a cross-sectional study. Methods: Seventy-five postmenopausal women with RA were examined by DXA measuring DXA-BMD of the forearm, total hip and lumbar spine, by scoring joint destruction on plain radiographs by the method of Larsen and by DXR-BMD in metacarpals two to four. The DXR-BMD results of the RA women were compared with an age and sex-matched reference database. A function of DXR-BMD in relation to age and disease duration was created. Associations were investigated by bivariate and mu... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5350268 Mon, 24 Oct 2011 04:00:00 +0100 5350268 http://www.medworm.com/index.php?rid=5325803&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F239 DiscussionNew hybrid systems might improve the outcome of lumbar spine fusion. To date, there is no convincing published data on effectiveness or safety of these topping off systems. High quality data is required to evaluate the benefits and drawbacks of topping off devices. If only because these devices are quite expensive compared to conventional fusion implants, nonessential use should be avoided. In fact, these high costs necessitate efforts by health care providers to evaluate the effects of these implants. Randomized clinical trials are highly recommended to evaluate the benefits or harm to the patient.Trial registration:Clinicaltrials.gov NCT01224379 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5325803 Tue, 18 Oct 2011 04:00:00 +0100 5325803 http://www.medworm.com/index.php?rid=5325805&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F237 Conclusions: The present results show how Hsp90beta modulates NO production and NO-mediated cellular death in human OA chondrocytes. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5325805 Mon, 17 Oct 2011 04:00:00 +0100 5325805 http://www.medworm.com/index.php?rid=5325804&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F238 This study will be a multi-center observational diagnostic study in which the data will be collected cross-sectionally. The study population will consist of all consecutive adult patients ([greater than or equal to]18 years) presenting with acute wrist trauma at the Emergency Department in the participating hospitals.This research comprises two components: one study will be conducted to determine which clinical parameters are predictive for the presence of a distal radius fracture in adult patients presenting to the Emergency Department following acute wrist trauma. These clinical parameters are defined by trauma-mechanism, physical examination, and functional testing. This data will be collected in two of the three participating hospitals and will be assessed by using logistic regression ... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5325804 Mon, 17 Oct 2011 04:00:00 +0100 5325804 http://www.medworm.com/index.php?rid=5317274&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F234 Conclusions: Our findings suggest that the MRI abnormalities examined are not major predictors of outcome in patients with LBP. They give no support to the use of MRI findings as a way of refining case definition for LBP in epidemiological research. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5317274 Fri, 14 Oct 2011 04:00:00 +0100 5317274 http://www.medworm.com/index.php?rid=5317273&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F235 Conclusions: Taken together, our data show that tryptase can stimulate myoblast proliferation and this effect is part of a signaling cascade dependent on PAR-2 activation and on the downstream activation of COX-2. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5317273 Fri, 14 Oct 2011 04:00:00 +0100 5317273 http://www.medworm.com/index.php?rid=5317272&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F236 Conclusions: The findings from this exploratory study reveal how others and wider social circumstances might contribute both to the propensity of persistent back pain and to its consequences. This is an area that has received little attention to date, and wider support of these findings may usefully inform the design of future intervention programmes aimed at restoring work participation. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5317272 Fri, 14 Oct 2011 04:00:00 +0100 5317272 http://www.medworm.com/index.php?rid=5317275&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F233 Conclusions: Simultaneous quadruple TJA in equally disabling OA of bilateral deformed knees and ankles resulted in a better functional outcome and faster recovery compared to the average reported results after TKA and TAA in literature. However, careful preoperative planning, extensive patient education, and two complete surgical teams were considered essential for successful performance. To the best of our knowledge this is the first case report in literature about quadruple major total joint arthroplasty implanted during the same anesthesia in the same patient. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5317275 Thu, 13 Oct 2011 04:00:00 +0100 5317275 http://www.medworm.com/index.php?rid=5306496&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F231 Background: Examine 90-day postoperative mortality and its predictors following shoulder arthroplasty Methods: We identified vital status of all adults who underwent primary shoulder arthroplasty (Total shoulder arthroplasty (TSA) or humeral head replacement (HHR)) at the Mayo Clinic from 1976-2008, using the prospectively collected information from Total Joint Registry. We used univariate logistic regression models to assess the association of gender, age, body mass index, American Society of Anesthesiologist (ASA) class, Deyo-Charlson comorbidity index, an underlying diagnosis and implant fixation with odds of 90-day mortality after TSA or HHR. Multivariable models additionally adjusted for the type of surgery (TSA versus HHR). Adjusted Odds ratio (OR) with 95% confidence interval (CI) ... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5306496 Wed, 12 Oct 2011 04:00:00 +0100 5306496 http://www.medworm.com/index.php?rid=5306495&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F232 DISCUSSION: The results of this trial will provide insight into the cost-effectiveness of adding exercise therapy to GPs' care in the treatment of OA of the hip. This trial is registered in the Dutch trial registry (www.trialregister.nl): trial number NTR1462. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5306495 Wed, 12 Oct 2011 04:00:00 +0100 5306495 http://www.medworm.com/index.php?rid=5306497&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F229 DiscussionThe TOPSHOCK study is the first randomised controlled trial that directly compares the effectiveness of focused shockwave therapy and radial shockwave therapy, both in combination with eccentric decline squat training, for treating patellar tendinopathy.Trial registration: Trial registration number NTR2774. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5306497 Tue, 11 Oct 2011 04:00:00 +0100 5306497 http://www.medworm.com/index.php?rid=5306498&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F228 Conclusions: Patients' explanatory models of arthritis influenced the psychosocial effects of the disease and coping mechanisms used. Given the increasing reach of global health programs, understanding these culturally influenced perceptions of disease will be crucial in successfully treating chronic diseases in the developing world. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5306498 Mon, 10 Oct 2011 04:00:00 +0100 5306498 http://www.medworm.com/index.php?rid=5298449&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F223 Conclusions: Within the last year most symphony orchestra musicians experienced musculoskeletal symptoms in the neck, back or upper extremities. The symptoms impacted on their level of function in and outside work and were reflected in their health behaviour. Generally women had a higher risk than men and woodwind players a lower risk than other instrumentalists. Finally, symptoms were more frequent and lasted longer in the musicians than in the general workforce. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5298449 Fri, 07 Oct 2011 04:00:00 +0100 5298449 http://www.medworm.com/index.php?rid=5298448&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F224 Conclusion: Fibromyalgia is a common condition; the 1.6% prevalence calculated in the French population in our study corroborates the figures published in the European literature. Our results also suggest that criteria such as regional pain score, stress level or SF36 quality of life, could represent useful tools in fibromyalgia diagnosis. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5298448 Fri, 07 Oct 2011 04:00:00 +0100 5298448 http://www.medworm.com/index.php?rid=5298447&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F225 Background: After menopause, rapid bone mass loss occurs in response to hypoestrogenism. Several studies suggest that muscle mass and bone mineral density (BMD) are positively associated in postmenopausal women. Therefore, it may be assumed that postmenopausal low appendicular muscle mass (aMM) can increase BMD loss in a short period of time. Objective: The purpose of this study was to assess relationship of aMM with femoral neck BMD in postmenopausal women. Methods: Prospective, controlled clinical Trial including 64 women aged 45-70 years, who had not had their last menstruation for at least one year. Subjects were divided into two groups: low aMM (n=32), and normal aMM (n-32). Femoral neck BMD and muscle mass were measured by DXA at baseline and after twelve months. Pairwise and indepen... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5298447 Fri, 07 Oct 2011 04:00:00 +0100 5298447 http://www.medworm.com/index.php?rid=5298446&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F226 DiscussionAs TKR use expands, it is important to develop methods to identify patients at risk for sub-optimal functional outcome and to effectively intervene with the goal of optimizing functional outcomes. If shown efficacious, this peri-TKR intervention has the potential to change the paradigm for successful post-TKR care. We hypothesize that Patient Self-Management Support to enhance adherence to independent activity and exercise will enhance uniform, optimal improvement in post-TKR function and patient autonomy, the ultimate goals of TKR.Trial Registration: www.clinicaltrials.gov # NCT00566826 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5298446 Fri, 07 Oct 2011 04:00:00 +0100 5298446 http://www.medworm.com/index.php?rid=5298450&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F222 Conclusions: Patients who had undergone total hip arthroplasty have impaired long-term self-reported physical quality of life and hip functionality but they still perform physically better than untreated patients with advanced hip osteoarthritis. However, the level of post-surgical satisfaction is high. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5298450 Thu, 06 Oct 2011 04:00:00 +0100 5298450 http://www.medworm.com/index.php?rid=5288056&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F221 Conclusions: The present study suggests that five weekly intra-articular injections of sodium hyaluronate are well tolerated, can provide sustained relief of pain, and can improve function in Asian patients with osteoarthritis of the knee.Level of Evidence: Therapeutic study, Level I-1a (randomized controlled trial with a significant difference).Trial registration: ClinicalTrials.gov Identifier: NCT01319461 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5288056 Thu, 06 Oct 2011 04:00:00 +0100 5288056 http://www.medworm.com/index.php?rid=5288059&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F218 Conclusion: Negative emotional cognitions, active cognitive coping, control beliefs and expectations of chronicity seem to constitute principal domains of cognitive processes in CWP. These findings contribute to the understanding of overlap and uniqueness of cognitive concepts in chronic widespread pain. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5288059 Wed, 05 Oct 2011 04:00:00 +0100 5288059 http://www.medworm.com/index.php?rid=5288058&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F219 Background: Observational studies have previously shown that adverse events following manipulation to the neck and/or back are relatively common, although these reactions tend to be mild in intensity and self-limiting. However, no prospective study has examined the incidence of adverse reactions following spinal adjustments using upper cervical techniques, and the impact of this care on clinical outcomes. Methods: Consecutive new patients from the offices of 83 chiropractors were recruited for this practice-based study. Clinical outcome measures included 1) Neck pain disability index (100-point scale), 2) Oswestry back pain index (100-point scale), 3) 11-point numerical rating scale (NRS) for neck, headache, midback, and low back pain, 4) treatment satisfaction, and 5) Symptomatic Reaction... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5288058 Wed, 05 Oct 2011 04:00:00 +0100 5288058 http://www.medworm.com/index.php?rid=5288057&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F220 The objectives of this pilot study were to characterize fluctuations in pain during acute LBP, to determine whether self-reported 'flares' of pain represent discrete periods of increased pain intensity, and to examine whether the frequency of flares was associated with back-related disability outcomes. Methods: We conducted a cohort study of acute LBP patients utilizing frequent serial assessments and Internet-based data collection. Adults with acute LBP (lasting [less than or equal to]3 months) completed questionnaires at the time of seeking care, and at both 3-day and 1-week intervals, for 6 weeks. Back pain was measured using a numerical pain rating scale (NPRS), and disability was measured using the Oswestry Disability Index (ODI). A pain flare was defined as 'a period of increased pai... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5288057 Wed, 05 Oct 2011 04:00:00 +0100 5288057 http://www.medworm.com/index.php?rid=5276399&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F216 Conclusions: A short lumbosacral curve accompanied with a long thoracic or thoracolumbar curve toward the opposite side, and a relatively straight sagittal profile have been noted in all the patients. The direction of lumbosacral curve and trunk shift was related to the side of disc herniation. A majority of patients have a small curve size while assosiated with a significant coronal imbalance. Earlier decompression can provide a greater opportunity for spontaneous correction of scoliosis.Keywords Scoliosis; Adolescent; Lumbar disc herniation; Discetomy (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5276399 Fri, 30 Sep 2011 04:00:00 +0100 5276399 http://www.medworm.com/index.php?rid=5276398&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F217 Background: Bone marrow lesions (BMLs), common osteoarthritis-related magnetic resonance imaging findings, are associated with osteoarthritis progression and pain. However, there are no articles describing the use of 3-dimensional quantitative assessments to explore the longitudinal relationship between BMLs and hyaline cartilage loss. The purpose of this study was to assess the cross-sectional and longitudinal descriptive characteristics of BMLs with a simple measurement of approximate BML volume, and describe the cross-sectional and longitudinal relationships between BML size and the extent of hyaline cartilage damage. Methods: 107 participants with baseline and 24-month follow-up magnetic resonance images from a clinical trial were included with symptomatic knee osteoarthritis. An 'inde... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5276398 Fri, 30 Sep 2011 04:00:00 +0100 5276398 http://www.medworm.com/index.php?rid=5263194&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F213 Conclusions: The tissue regenerated by using the DN gel was genetically similar but not completely identical to articular cartilage. The genetic data shown in this study are useful for future studies to identify specific genes involved in spontaneous cartilage regeneration. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5263194 Thu, 29 Sep 2011 04:00:00 +0100 5263194 http://www.medworm.com/index.php?rid=5263193&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F214 Conclusions: This experimental animal model could serve as a standard model in comparative research. A well defined standard model would reduce the number of experimental animals needed in future studies and would therefore add to ethical considerations. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5263193 Thu, 29 Sep 2011 04:00:00 +0100 5263193 http://www.medworm.com/index.php?rid=5263192&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F215 Conclusions: PEMF stimulation can prevent steroid-induced osteonecrosis in rats, and the underlying mechanisms involve decreased serum lipid levels and increased expression of TGF-beta1. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5263192 Thu, 29 Sep 2011 04:00:00 +0100 5263192 http://www.medworm.com/index.php?rid=5263197&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F210 This study was designed as three way randomized controlled trial with one year follow-up. Healthy individuals between 12 and 70 years of age, who were actively participating in sports and who had sustained a lateral ankle sprain in the two months prior to inclusion, were eligible for inclusion. After subjects had finished ankle sprain treatment by means of usual care, they were randomised to any of the three study groups. Subjects in group 1 received an eight week neuromuscular training program, subjects in group 2 received a sports brace to be worn during all sports activities for the duration of one year, and group 3 received a combination of the neuromuscular training program and a sports brace to be worn during all sports activities for the duration of eight weeks. Outcomes were assess... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5263197 Tue, 27 Sep 2011 04:00:00 +0100 5263197 http://www.medworm.com/index.php?rid=5263196&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F211 Conclusion: It can be concluded that CLBP patients in general have worse motor task performance compared to healthy subjects and that provoking pain-related cognitions further worsened performance. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5263196 Tue, 27 Sep 2011 04:00:00 +0100 5263196 http://www.medworm.com/index.php?rid=5263195&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F212 Conclusions: To confirm the clinical suspicion, the final diagnosis of chronic instability of the anterior syndesmosis can be made during arthroscopy of the ankle. Cartilage damage to the medial side of the tibiotalar joint is often seen and might be the result of syndesmotic instability. Good results are achieved by anatomical reconstruction of the anterior syndesmosis, and all patients in this study would undergo the surgery again if necessary. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5263195 Tue, 27 Sep 2011 04:00:00 +0100 5263195 http://www.medworm.com/index.php?rid=5263198&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F209 Conclusion: Teriparatide, zoledronic acid and denosumab have the highest probabilities of being most efficacious for non-vertebral and vertebral fractures, and having the greatest effect sizes. The estimates from indirect comparisons were robust to differences in methodology. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5263198 Mon, 26 Sep 2011 04:00:00 +0100 5263198 http://www.medworm.com/index.php?rid=5252411&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F207 DiscussionTo our knowledge this study will be the first to compare two exercise programs for a specific subgroup of patients with NSLBP and MCI. Results of this study will provide insight into the effectiveness of movement control exercise and contribute to our understanding of the mechanisms behind MCI and its relation to NSLBP.Trial registration: Current Controlled Trials ISRCTN80064281 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5252411 Fri, 23 Sep 2011 04:00:00 +0100 5252411 http://www.medworm.com/index.php?rid=5240794&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F206 We report herein our initial experience with a novel vertebral augmentation technique designed to treat symptomatic vertebral osteoporotic fractures and osteolytic metastases with minimal cement extravasation. Methods: Forty-two vertebral fractures were identified in 26 consecutive patients (mean age 74+/-9 years). All patients were treated with a novel percutaneous vertebral augmentation device (Kiva(R) VCF Treatment System, Benvenue Medical, Santa Clara, CA, USA). Indications for surgery included recent ([less than or equal to] 3 months) symptomatic osteoporotic vertebral fracture (n=34) and pathologic vertebral fractures (e.g. metabolic bone disease, myeloma, metastasis) (n=8) located between T10 and S1. Patient outcomes were evaluated pre-treatment and at 2- and 6-month follow-up visit... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5240794 Thu, 22 Sep 2011 04:00:00 +0100 5240794 http://www.medworm.com/index.php?rid=5240795&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F205 This study evaluates the effect of implementing strength training at the workplace on non-specific neck and shoulder pain among industrial workers. Methods: Cluster-randomized controlled trial involving 537 adults from occupations with high prevalence of neck and shoulder pain (industrial production units). Participants were randomized to 20 weeks of high-intensity strength training for the neck and shoulders three times a week (n = 282) or a control group receiving advice to stay physically active (n = 255). The strength training program followed principles of progressive overload and periodization. The primary outcome was changes in self-reported neck and shoulder pain intensity (scale 0-9). Results: 85% of the participants followed the strength training program on a weekly basis. In the... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5240795 Wed, 21 Sep 2011 04:00:00 +0100 5240795 http://www.medworm.com/index.php?rid=5240797&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F203 Background: The role played by the thoracolumbar fascia in chronic low back pain is poorly understood. The thoracolumbar fascia is composed of dense connective tissue layers separated by layers of loose connective tissue that normally allow the dense layers to glide past one another during trunk motion. The goal of this study was to quantify shear plane motion within the thoracolumbar fascia using ultrasound elasticity imaging in human subjects with and without chronic low back pain (LBP). Methods: We tested 121 human subjects, 50 without LBP and 71 with LBP of greater than 12 months duration. In each subject, an ultrasound cine-recording was acquired on the right and left sides of the back during passive trunk flexion using a motorized articulated table with the hinge point of the table a... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5240797 Mon, 19 Sep 2011 04:00:00 +0100 5240797 http://www.medworm.com/index.php?rid=5240796&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F204 Conclusions: Subsequent-line anti-TNF therapy cohorts had higher rates of discontinuation, dose escalation, and shorter time to discontinuation than first-line anti-TNF cohorts. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5240796 Mon, 19 Sep 2011 04:00:00 +0100 5240796 http://www.medworm.com/index.php?rid=5228572&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F200 The journal has been informed by the authors' institution that, contrary to the statement in this article [1], the Macquarie University Human Ethics Committee did not receive an application for ethics approval for this study. As the study was conducted without institutional ethics committee oversight, this article has been retracted.References1. The effect of a sports chiropractic manual therapy intervention on the prevention of back pain, hamstring and lower limb injuries in semi-elite Australian Rules footballers: A randomized controlled trial. Wayne Hoskins, Henry Pollard. BMC Musculoskeletal Disorders 2010, 11:64. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5228572 Tue, 13 Sep 2011 04:00:00 +0100 5228572 http://www.medworm.com/index.php?rid=5228571&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F201 DiscussionThis pragmatic, multi-centre trial is due to deliver results in December 2013.Trial registration:Current Controlled Trials ISRCTN31379280UKCRN portfolio ID 8956 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5228571 Tue, 13 Sep 2011 04:00:00 +0100 5228571 http://www.medworm.com/index.php?rid=5228570&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F202 Background: Prior studies that have concluded that disk degeneration uniformly precedes facet degeneration have been based on convenience samples of individuals with low back pain. We conducted a study to examine whether the view that spinal degeneration begins with the anterior spinal structures is supported by epidemiologic observations of degeneration in a community-based population. Methods: 361 participants from the Framingham Heart Study were included in this study. The prevalences of anterior vertebral structure degeneration (disk height loss) and posterior vertebral structure degeneration (facet joint osteoarthritis) were characterized by CT imaging. The cohort was divided into the structural subgroups of participants with 1) no degeneration, 2) isolated anterior degeneration (with... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5228570 Tue, 13 Sep 2011 04:00:00 +0100 5228570 http://www.medworm.com/index.php?rid=5212370&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F199 Background: Maximal isometric quadriceps strength deficits have been widely reported in studies of knee osteoarthritis (OA), however little is known about the effect of osteoarthritis knee pain on submaximal quadriceps neuromuscular function. The purpose of this study was to measure vastus medialis motor unit (MU) properties in participants with knee OA, during submaximal isometric contractions. Methods: Vastus medialis motor unit potential (MUP) parameters were assessed in 8 patients with knee OA and 8 healthy, sex and age-matched controls during submaximal isometric contractions (20% of maximum isometric torque). Unpaired t-tests were used to compare groups for demographic and muscle parameters. Results: Maximum knee extension torque was ~22% lower in the OA group, a difference that was ... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5212370 Tue, 13 Sep 2011 04:00:00 +0100 5212370 http://www.medworm.com/index.php?rid=5212371&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F198 Background: Choice of appropriate MR pulse sequence is important for any research studies using imaging-derived data. The aim of this study was to compare semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts using intermediate-weighted (IW) fat-suppressed (fs) spin echo and Dual Echo Steady State (DESS) sequences on 3 T MRI. Methods: Included were 201 subjects aged 35-65 with frequent knee pain. 3T MRI was performed with the same sequence protocol as in the Osteoarthritis Initiative (OAI). In a primary reading subchondral bone marrow edema-like lesions were assessed according to the WORMS system. Two hundred subregions with such lesions were randomly chosen. The extent of subchondral bone marrow edema-like lesions was re-evaluated separately using... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5212371 Fri, 09 Sep 2011 04:00:00 +0100 5212371 http://www.medworm.com/index.php?rid=5148712&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F195 Conclusions: Six monthly intra-articular injections of Hylan G-F 20 administered to patients with symptomatic knee OA have a beneficial effect on knee cartilage preservation measured by both cartilage volume and cartilage defects. Hylan G-F 20 warrants further evaluation in larger clinical trials as a possible disease-modifying agent in the treatment of knee OA.Trial Registration: The study was registered with ClinicalTrials.gov (NCT00393393). (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148712 Tue, 23 Aug 2011 23:00:00 +0100 5148712 http://www.medworm.com/index.php?rid=5148711&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F196 DiscussionThis trial will provide level-1 evidence for the comparison of consolidation and functional outcome between two standardised treatment options for dislocated midshaft clavicular fractures. The gathered data may support the development of a clinical guideline for treatment of clavicular fractures.Trial registrationNetherlands National Trial Register (NTR2399) (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148711 Tue, 23 Aug 2011 23:00:00 +0100 5148711 http://www.medworm.com/index.php?rid=5148710&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F197 Conclusions: In summary, this study demonstrated the temporal and cohesive gene expression changes in articular cartilage and subchondral bone using known markers of OA progression. The findings here support genome-wide profiling efforts to elucidate the sequential and complex regulation of the disease. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148710 Tue, 23 Aug 2011 23:00:00 +0100 5148710 http://www.medworm.com/index.php?rid=5148713&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F194 The objective of the study is to assess the cost-effectiveness and cost-utility analysis of a multidisciplinary biopsychosocial educational group intervention (MBEGI) of non-specific sub-acute LBP in comparison with the usual care in the working population recruited in primary healthcare centres.Methods/designThe study design is a cost-effectiveness and cost-utility analysis of a MBEGI in comparison with the usual care of non-specific sub-acute LBP.Measures on effectiveness and costs of both interventions will be obtained from a cluster randomised controlled clinical trial carried out in 38 Catalan primary health care centres, enrolling 932 patients between 18 and 65 years old with a diagnosis of non-specific sub-acute LBP. Effectiveness measures are: pharmaceutical treatments, work sick l... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148713 Sun, 21 Aug 2011 23:00:00 +0100 5148713 http://www.medworm.com/index.php?rid=5148716&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F191 Conclusions: The standardised MST is considered a reliable leg function test for clinical practice. The MSH was related to knee extension strength and self-reported physical function. The precision of the MST for identification of limitations in physical function needs further investigation. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148716 Thu, 18 Aug 2011 23:00:00 +0100 5148716 http://www.medworm.com/index.php?rid=5148715&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F192 DiscussionIn the past, computer navigation has improved the accuracy of component positioning. So far, there are only few objective data quantifying the risks and benefits of computer navigated THA. Therefore, this study has been designed to compare minimally invasive computer-navigated "femur first" THA with a conventional technique for minimally invasive THA. The results of this trial will be presented as soon as they become available.Trial registration number:DRKS00000739 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148715 Thu, 18 Aug 2011 23:00:00 +0100 5148715 http://www.medworm.com/index.php?rid=5148714&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F193 DiscussionThis consortium is a collaboration between different research groups, aiming to provide insight into the course of back complaints in older people and to identify prognostic factors for the transition from acute back complaints to chronic back complaints in older persons. The BACE consortium allows to investigate differences between older people with back complaints and the health care system in the different countries and to increase the statistical power by enabling meta-analyses using the individual patient data. Additional research groups worldwide are invited to join the BACE consortium. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148714 Thu, 18 Aug 2011 23:00:00 +0100 5148714 http://www.medworm.com/index.php?rid=5148718&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F189 Conclusions: The results of this study shows that elderly patients aged over 75 benefit from instrumented lumbar fusion. The study suggests that there is no need to force an intervertebral fusion because elderly patients do not seem to benefit from this procedure.KeywordsPosterolateral fusion, intervertebral fusion, elderly, outcome (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148718 Wed, 17 Aug 2011 23:00:00 +0100 5148718 http://www.medworm.com/index.php?rid=5148717&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F190 Conclusion: The computerized questionnaires gave comparable results to answers given on paper. Patient characteristics did not influence results and implementation was feasible. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148717 Wed, 17 Aug 2011 23:00:00 +0100 5148717 http://www.medworm.com/index.php?rid=5148719&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F188 DiscussionThis pragmatic study will provide information about the effectiveness and cost-effectiveness of taping in patients presenting with clinical signs of SAIS.Trial registration: Trial registration number: NTR2575 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5148719 Tue, 16 Aug 2011 23:00:00 +0100 5148719 http://www.medworm.com/index.php?rid=5134184&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F185 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5134184 Sun, 14 Aug 2011 23:00:00 +0100 5134184 http://www.medworm.com/index.php?rid=5134183&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F186 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5134183 Sun, 14 Aug 2011 23:00:00 +0100 5134183 http://www.medworm.com/index.php?rid=5121415&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F184 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5121415 Thu, 11 Aug 2011 23:00:00 +0100 5121415 http://www.medworm.com/index.php?rid=5112206&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F181 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5112206 Tue, 09 Aug 2011 23:00:00 +0100 5112206 http://www.medworm.com/index.php?rid=5112205&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F182 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5112205 Tue, 09 Aug 2011 23:00:00 +0100 5112205 http://www.medworm.com/index.php?rid=5112204&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F183 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5112204 Tue, 09 Aug 2011 23:00:00 +0100 5112204 http://www.medworm.com/index.php?rid=5099377&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F179 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5099377 Thu, 04 Aug 2011 23:00:00 +0100 5099377 http://www.medworm.com/index.php?rid=5090222&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F178 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5090222 Tue, 02 Aug 2011 23:00:00 +0100 5090222 http://www.medworm.com/index.php?rid=5090223&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F177 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5090223 Mon, 01 Aug 2011 23:00:00 +0100 5090223 http://www.medworm.com/index.php?rid=5081890&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F176 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5081890 Sun, 31 Jul 2011 23:00:00 +0100 5081890 http://www.medworm.com/index.php?rid=5072417&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F175 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5072417 Wed, 27 Jul 2011 23:00:00 +0100 5072417 http://www.medworm.com/index.php?rid=5065331&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F174 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5065331 Sun, 24 Jul 2011 23:00:00 +0100 5065331 http://www.medworm.com/index.php?rid=5054442&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F169 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5054442 Thu, 21 Jul 2011 23:00:00 +0100 5054442 http://www.medworm.com/index.php?rid=5054441&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F170 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5054441 Thu, 21 Jul 2011 23:00:00 +0100 5054441 http://www.medworm.com/index.php?rid=5054440&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F171 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5054440 Thu, 21 Jul 2011 23:00:00 +0100 5054440 http://www.medworm.com/index.php?rid=5054439&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F172 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5054439 Thu, 21 Jul 2011 23:00:00 +0100 5054439 http://www.medworm.com/index.php?rid=5054438&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F173 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5054438 Thu, 21 Jul 2011 23:00:00 +0100 5054438 http://www.medworm.com/index.php?rid=5042933&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F168 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5042933 Wed, 20 Jul 2011 23:00:00 +0100 5042933 http://www.medworm.com/index.php?rid=5042932&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F166 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5042932 Wed, 20 Jul 2011 23:00:00 +0100 5042932 http://www.medworm.com/index.php?rid=5042931&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F167 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5042931 Wed, 20 Jul 2011 23:00:00 +0100 5042931 http://www.medworm.com/index.php?rid=5042934&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F165 ${item.shortDescription} (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5042934 Sun, 17 Jul 2011 23:00:00 +0100 5042934 http://www.medworm.com/index.php?rid=5032186&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F161 Background: Despite the large volume of research dedicated to understanding chronic low back pain (CLBP), patient outcomes remain modest while healthcare costs continue to rise, creating a major public health burden. Health literacy - the ability to seek, understand and utilise health information - has been identified as an important factor in the course of other chronic conditions and may be important in the aetiology of CLBP. Many of the currently available health literacy measurement tools are limited since they measure narrow aspects of health literacy. The Health Literacy Measurement Scale (HeLMS) was developed recently to measure broader elements of health literacy. The aim of this study was to measure broad elements of health literacy among individuals with CLBP and without LBP usin... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5032186 Thu, 14 Jul 2011 23:00:00 +0100 5032186 http://www.medworm.com/index.php?rid=5032185&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F162 Conclusions: COP mean velocity and sway area are closely related to self-reported pain scores. This relationship may be of clinical use as an objective monitoring tool for patients under treatment or rehabilitation. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5032185 Thu, 14 Jul 2011 23:00:00 +0100 5032185 http://www.medworm.com/index.php?rid=5032184&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F163 Conclusion: Our results underline the transfecting capability of this vector and support the idea that BMP-2 might diminish osseointegration. Further studies are necessary to specify the exact mechanisms and the systemic effects. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5032184 Thu, 14 Jul 2011 23:00:00 +0100 5032184 http://www.medworm.com/index.php?rid=5032183&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F164 Conclusions: TN-C expression in the knee cartilage and TN-C levels measured in the synovial fluid are significantly enhanced in OA patients. Our findings suggest that the elevated levels of TN-C could induce inflammatory mediators and promote matrix degradation in OA joints. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5032183 Thu, 14 Jul 2011 23:00:00 +0100 5032183 http://www.medworm.com/index.php?rid=5032187&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F160 Conclusion: Our findings demonstrated that three SNPs (rs1799889, rs2227631, and rs11178) of the PAI-1 gene were associated with ONFH risk. This study also suggests that PAI-1 SNPs may play an important role in ONFH. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5032187 Wed, 13 Jul 2011 23:00:00 +0100 5032187 http://www.medworm.com/index.php?rid=5023164&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F157 Conclusions: The economic burden of musculoskeletal disease in Korea is substantial. As the Korean population continues to age, the economic burden of musculoskeletal disease will continue to increase. Policy measures aimed at controlling the cost of musculoskeletal disease are therefore required. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5023164 Tue, 12 Jul 2011 23:00:00 +0100 5023164 http://www.medworm.com/index.php?rid=5023163&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F158 The journal has been informed by the authors' institution that, contrary to the statement in this article [1], the Macquarie University Human Ethics Committee did not receive an application for ethics approval for this study. As the study was conducted without institutional ethics committee oversight, this article has been retracted.References1. Low back pain status in elite and semi-elite Australian football codes: a cross-sectional survey of football (soccer), Australian-Rules, rugby league, rugby union and non-athletic controls: Wayne Hoskins, Henry Pollard, Chris Daff, Andrew Odell, Peter Garbutt, Andrew McHardy, Kate Hardy and George Dragasevic. BMC Musculoskeletal Disorders 2009, 10:38 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5023163 Tue, 12 Jul 2011 23:00:00 +0100 5023163 http://www.medworm.com/index.php?rid=5023162&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F159 The journal has been informed by the authors' institution that, contrary to the statement in this article [1], the Macquarie University Human Ethics Committee did not receive an application for ethics approval for this study. As the study was conducted without institutional ethics committee oversight, this article has been retracted.References1. Low back pain in junior Australian Rules football: a cross-sectional survey of elite juniors, non-elite juniors and non-football playing controls: Wayne Hoskins, Henry Pollard, Chris Daff, Andrew Odell, Peter Garbutt, Andrew McHardy, Kate Hardy and George Dragasevic. BMC Musculoskeletal Disorders 2010, 11:241 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5023162 Tue, 12 Jul 2011 23:00:00 +0100 5023162 http://www.medworm.com/index.php?rid=5012592&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F156 DiscussionThe findings will improve the cost-effective evidence based management of hand OA.Trial registration identifier ISRCTN33870549 (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5012592 Sun, 10 Jul 2011 23:00:00 +0100 5012592 http://www.medworm.com/index.php?rid=5012593&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F155 Conclusions: The inter-examiner reliability for goniometric measurement of hip abduction in children with CP was low, in keeping with other results found in previous publications. The inclinometer has proved to be a highly reliable tool for measuring the hip abduction range of motion in children with CP, which opens up new possibilities in this field, despite having some usage limitations. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5012593 Sat, 09 Jul 2011 23:00:00 +0100 5012593 http://www.medworm.com/index.php?rid=5012594&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F154 DiscussionThe results of this trial will give unique evidence regarding the cost-effectiveness of US as a diagnostic triage tool in the management of SP in primary care. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5012594 Thu, 07 Jul 2011 23:00:00 +0100 5012594 http://www.medworm.com/index.php?rid=5012595&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F153 Conclusion: The addition of canakinumab 150 mg SC q4wk improves therapeutic responses among patients who have active RA despite stable treatment with methotrexate.(ClinicalTrials.gov identifier: NCT00784628) (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5012595 Wed, 06 Jul 2011 23:00:00 +0100 5012595 http://www.medworm.com/index.php?rid=5001806&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F152 Conclusions: To our knowledge, the CINS trial will be the largest, randomized trial of psychological and nutritional interventions for chronic low back pain patients to date. It will provide important information regarding the effectiveness of CBT and seal oil for chronic low back pain patients.Trial registrationwww.clinicaltrials.gov, with registration number NCT00463970. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5001806 Wed, 06 Jul 2011 23:00:00 +0100 5001806 http://www.medworm.com/index.php?rid=5001807&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F151 The objective of this study protocol is to investigate the effectiveness of the the intra-operative use of the 3D-RX-system as compared to the conventional 2D-fluoroscopy in patients with traumatic intra-articular fractures of the wrist, ankle and calcaneus. The effectiveness will be assessed in two different areas: 1) the quality of fracture reduction and fixation, based on the current golden standard, Computed Tomography. 2) The patient-relevant outcomes like functional outcome range of motion and pain. In addition, the diagnostic accuracy of the 3D-RX-scan will be determined in a clinical setting and a cost-effectiveness as well as a cost-utility analysis will be performed.Methods/designIn this protocol for an international multicenter randomized clinical trial, adult patients (age > 17... BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5001807 Tue, 05 Jul 2011 23:00:00 +0100 5001807 http://www.medworm.com/index.php?rid=5001810&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F148 DiscussionThis pragmatic trial will determine if a rehabilitation program reduces activity limitation and improves quality of life, compared to advice alone, after immobilisation for ankle fracture. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5001810 Mon, 04 Jul 2011 23:00:00 +0100 5001810 http://www.medworm.com/index.php?rid=5001809&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F149 Conclusions: The HK-DQI is feasible and acceptable to patients. It can be used to assess whether patients with osteoarthritis are making informed decisions about surgery that are concordant with their goals. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5001809 Mon, 04 Jul 2011 23:00:00 +0100 5001809 http://www.medworm.com/index.php?rid=5001808&cid=s_29524_31_f&fid=29524&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-2474%2F12%2F150 Conclusions: The present study indicates a role for survivin in osteoarthritic cartilage and human chondrocytes. In vitro experiments indicated its involvement in cellular division and viability. Learning more about the functions of survivin in chondrocyte biology might further help toward understanding and modulating the complex processes of cartilage pathology and regeneration. (Source: BMC Musculoskeletal Disorders) BMC Musculoskeletal Disorders journals http://www.medworm.com/rss/comments.php?id=5001808 Mon, 04 Jul 2011 23:00:00 +0100 5001808