BMC Psychiatry - Latest articles via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'BMC Psychiatry - Latest articles' source. Tue, 07 Feb 2012 09:35:42 +0100 Validation of the Chinese version of the "Mood Disorder Questionnaire" for screening bipolar disorder among patients with a current depressive episode http://www.medworm.com/index.php?rid=5645236&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F8 Conclusions: Our results show that the Chinese version of MDQ is a valid tool for screening BPD in a group of patients with current depressive episode on the Chinese mainland. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5645236 Tue, 31 Jan 2012 05:00:00 +0100 5645236 The characteristics and activities of child and adolescent mental health services in Italy: a regional survey http://www.medworm.com/index.php?rid=5645237&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F7 Conclusion: The percentage of young people in contact with CAMHS for mental disorders is in line with those observed in previous epidemiological studies. The overall number of child psychiatrists per 100,000 inhabitants is one of the highest in Europe and it is comparable with the most well equipped areas in the US. This comparison should be interpreted with caution, however, because in Italy, child psychiatrists also treat neurological disorders. Critical areas requiring improvement are: the uneven utilisation of standardised assessment procedures and the limited availability of dedicated emergency services during non-office hours (e.g., nights and holidays).KeywordsChild and Adolescent Mental Health Services (CAMHS); Process of care; Adolescence; Child Psychiatry. (Source: BMC Psychiatry... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5645237 Mon, 30 Jan 2012 05:00:00 +0100 5645237 Depression and Anxiety in Patients with Rheumatoid Arthritis: Prevalence rates based on a comparison of the Depression, Anxiety and Stress Scale (DASS) and the Hospital, Anxiety and Depression Scale (HADS) http://www.medworm.com/index.php?rid=5626413&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F6 Conclusions: This study provides further support for high prevalence of depression and anxiety in RA. It also shows that while these two scales provide a good indication of possible depression and anxiety, the estimates of prevalence so derived could vary, particularly for anxiety. These findings are discussed in terms of comparisons across studies and selection of scales for clinical use. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5626413 Tue, 24 Jan 2012 05:00:00 +0100 5626413 Efficacy of a behavioral self-help treatment with or without therapist guidance for co-morbid and primary insomnia - a randomized controlled trial. http://www.medworm.com/index.php?rid=5626414&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F5 Background: Cognitive behavioral therapy is treatment of choice for insomnia, but availability is scarce. Self-help can increase availability at low cost, but evidence for its efficacy is limited, especially for the typical insomnia patient with co-morbid problems. We hypothesized that a cognitive behaviorally based self-help book is effective to treat insomnia in individuals, also with co-morbid problems, and that the effect is enhanced by adding brief therapist telephone support. Methods: Volunteer sample; 133 media-recruited adults with insomnia. History of sleep difficulties (mean [SD]) 11.8 [12.0] years. 92.5% had co-morbid problems (e.g. allergy, pain, and depression). Parallel randomized (block-randomization, n>21) controlled "open label" trial; three groups - bibliotherapy with (n=... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5626414 Sun, 22 Jan 2012 05:00:00 +0100 5626414 Frontal lobe changes occur early in the course of affective disorders in young people http://www.medworm.com/index.php?rid=5618368&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F4 Conclusions: This study suggests that, in terms of frontal grey matter changes, a major transition point may occur in the course of affective illness between early attenuated syndromes and later discrete illness stages. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5618368 Fri, 20 Jan 2012 05:00:00 +0100 5618368 The DARE study of relapse prevention in depression: design for a phase 1/2 translational randomised controlled trial involving mindfulness-based cognitive therapy and supported self monitoring http://www.medworm.com/index.php?rid=5618369&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F3 This study is designed as a prospective, multi-site, single-blind, randomised controlled trial using a group comparison design between involving the intervention, MBCT, and a self-monitoring comparison condition, Depression Relapse Active Monitoring (DRAM). Follow-up is over 2 years. The design of the study indicates recruitment from primary and secondary care of 204 participants who have a history of 3 or more episodes of Major Depression but who are currently well. Measures assessing depressive relapse/recurrence, time to first clinical intervention, treatment expectancy and a range of secondary outcomes and process variables are included. A health economics evaluation will be undertaken to assess the incremental cost of MBCT.DiscussionThe results of this trial, including an examination ... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5618369 Thu, 19 Jan 2012 05:00:00 +0100 5618369 Posttraumatic stress symptoms and health-related quality of life: a two year follow-up study of injury treated at the Emergency Department http://www.medworm.com/index.php?rid=5579284&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F1 Conclusions: Among patients treated at an ED posttraumatic stress symptoms indicative of PTSD were associated with a considerable decrease in HRQoL in both hospitalized and non-hospitalized patients. PTSD symptoms may therefore raise a major barrier for full recovery of injury patients of even minor levels of severity. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5579284 Mon, 09 Jan 2012 05:00:00 +0100 5579284 Elevated levels of serum IL-5 are associated with an increased likelihood of major depressive disorder http://www.medworm.com/index.php?rid=5579283&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F12%2F2 Conclusions: Elevated levels of IL-5, which uses the neural plasticity-related RAS GTPase-extracellular signal-regulated kinase (Ras-ERK) pathway to mediate its actions in the central nervous system (CNS), could be one of the factors underlying the depression-related changes in CNS plasticity. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5579283 Mon, 09 Jan 2012 05:00:00 +0100 5579283 Prevalence and risk factors of major depressive disorder in HIV/AIDS as seen in semi-urban Entebbe district, Uganda http://www.medworm.com/index.php?rid=5557509&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F205 Conclusion: Psychological and social factors were the main risk factors of MDD among ambulatory HIV positive persons with no evidence for the role of the neurotoxic effects of HIV. Treatment approaches for MDD in this patient group should be modeled on those used among non-HIV groups. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5557509 Fri, 30 Dec 2011 05:00:00 +0100 5557509 Discriminant and concurrent validity of a simplified DSM-based structured diagnostic instrument for the assessment of autism spectrum disorders in youth and young adults http://www.medworm.com/index.php?rid=5550857&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F204 Conclusions: A simplified DSM-based ASD structured diagnostic interview could serve as a useful diagnostic aid in the assessment of subjects with ASDs in clinical and research settings. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5550857 Fri, 30 Dec 2011 05:00:00 +0100 5550857 The association between delusional-like experiences, and tobacco, alcohol or cannabis use: a nationwide population-based survey. http://www.medworm.com/index.php?rid=5550859&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F202 Conclusions: While cannabis use disorders have been previously linked with DLE, our findings linking alcohol and tobacco use and DLE suggest that the influence of this substance on psychosis-related outcomes warrants closer scrutiny in longitudinal prospective studies. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5550859 Wed, 28 Dec 2011 05:00:00 +0100 5550859 The relationship, structure and profiles of schizophrenia measurements: a post-hoc analysis of the baseline measures from a randomized clinical trial http://www.medworm.com/index.php?rid=5550858&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F203 Conclusions: Researchers should consider collecting PANSS, SOFI, and SWN-K in their trials. This would allow a broad spectrum of assessments that would have the ability to capture a wide range of treatment outcomes and allow for a rich characterization of the subgroups involved. Additional research is needed to identify the critical cognitive measures.Clinical Trials Registration: Predicting Response to Risperidone Treatment Through Identification of Early-onset of Antipsychotic Drug Action in SchizophreniaClinicalTrials.gov identifier: NCT00337662; http://www.clinicaltrials.gov/ (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5550858 Wed, 28 Dec 2011 05:00:00 +0100 5550858 Chronic Depression: Development and Evaluation of the Luebeck Questionnaire for Recording Preoperational Thinking (LQPT) http://www.medworm.com/index.php?rid=5522079&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F199 Background: A standardized instrument for recording the specific cognitive psychopathology of chronically depressed patients has not yet been developed. Up until now, preoperational thinking of chronically depressed patients has only been described in case studies, or through the external observations of therapists. The aim of this study was to develop and evaluate a standardized self-assessment instrument for measuring preoperational thinking that sufficiently conforms to the quality criteria for test theory. Methods: The "Luebeck Questionnaire for Recording Preoperational Thinking (LQPT)" was developed and evaluated using a german sample consisting of 30 episodically depressed, 30 chronically depressed and 30 healthy volunteers. As an initial step the questionnaire was subjected to an it... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5522079 Tue, 20 Dec 2011 05:00:00 +0100 5522079 Efficacy of exposure versus cognitive therapy in anxiety disorders: systematic review and meta-analysis http://www.medworm.com/index.php?rid=5522078&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F200 Conclusions: On the basis of extant literature, there appears to be no evidence of differential efficacy between Cognitive Therapy and Exposure in PD, PTSD and OCD and strong evidence of superior efficacy of Cognitive Therapy in Social Phobia (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5522078 Tue, 20 Dec 2011 05:00:00 +0100 5522078 The role of Melancholia in Prostate Cancer Patients' Depression. http://www.medworm.com/index.php?rid=5522077&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F201 Conclusions: The strong presence of Melancholia in the depressive symptomatology of this sample of PCa patients suggests that some forms of treatment for depression may be more likely to succeed than others. The dominance of Anhedonia and Agitation over other symptoms of Melancholia also holds implications for treatment options when assisting these men to cope with their depression. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5522077 Tue, 20 Dec 2011 05:00:00 +0100 5522077 Seasonality in depressive and anxiety symptoms among primary care patients and in patients with depressive and anxiety disorders; results from the Netherlands Study of Depression and Anxiety http://www.medworm.com/index.php?rid=5522080&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F198 Conclusions: Seasonal differences in severity or type of depressive and anxiety symptoms, as measured with a general screening instrument and symptom questionnaires, were absent or small in effect size in a primary care population and in patient populations with a major depressive disorder and anxiety disorders. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5522080 Mon, 19 Dec 2011 05:00:00 +0100 5522080 Family Structure and Posttraumatic Stress Reactions: A Longitudinal Study Using Multilevel Analyses http://www.medworm.com/index.php?rid=5513731&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F195 Conclusions: These results indicate that adult household members may influence one another's posttraumatic stress reactions as well as their interpretations of the disaster experiences over time. Our findings suggest that multilevel methods may provide important information about family processes after disasters. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5513731 Thu, 15 Dec 2011 05:00:00 +0100 5513731 Seeking help for depression from family and friends: A qualitative analysis of perceived advantages and disadvantages http://www.medworm.com/index.php?rid=5513730&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F196 Conclusions: Family and friends are well placed to provide support which consumers perceive to be positive and which can assist them in obtaining formal mental health treatment. However, the input of some family members may be unhelpful or toxic. There may be benefits in undertaking community education and destigmatisation programs which target carers. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5513730 Thu, 15 Dec 2011 05:00:00 +0100 5513730 Association between second-generation antipsychotics and newly diagnosed treated diabetes mellitus: does the effect differ by dose? http://www.medworm.com/index.php?rid=5513729&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F197 Conclusions: In this large multi-site epidemiologic study, within each drug-specific stratum, the risk of diabetes for persons exposed to olanzapine, risperidone, and quetiapine was dose-dependent and elevated at therapeutic doses. In contrast, in aripiprazole-specific and ziprasidone-specific stratum, these newer agents were not associated with an increased risk of diabetes and dose-dependent relationships were not apparent. Although, these estimates should be interpreted with caution as they are imprecise due to small numbers. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5513729 Thu, 15 Dec 2011 05:00:00 +0100 5513729 Healthcare utilization and costs in patients beginning pharmacotherapy for generalized anxiety disorder: a retrospective cohort study http://www.medworm.com/index.php?rid=5502730&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F193 We examined healthcare utilization and costs over the 12-month periods preceding and following date of initial receipt of such therapy ("pretreatment" and "follow-up", respectively). Patients with incomplete data were excluded. Results: A total of 10,275 patients met all study inclusion criteria. Forty-eight percent of patients received SSRIs; 34%, benzodiazepines; and 6%, venlafaxine. SSRIs and venlafaxine were about three times more likely to be used on a long-term basis (>90 days) than benzodiazepines (p (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5502730 Mon, 12 Dec 2011 05:00:00 +0100 5502730 Experiences of treatment decision making for young people diagnosed with depressive disorders: a qualitative study in primary care and specialist mental health settings http://www.medworm.com/index.php?rid=5502729&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F194 Conclusions: This study supports clinical guidelines that advocate for young people diagnosed with depressive disorders to be involved in treatment decision making. In order to maximise engagement, involvement in treatment decision-making should be offered to all clients. Involvement should be negotiated explicitly and repeatedly, as desire for involvement may change over time. Caregiver involvement should be negotiated on an individual basis; however, all caregivers should be supported with information about mental disorders and treatment options. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5502729 Mon, 12 Dec 2011 05:00:00 +0100 5502729 Personality disorders and psychosocial problems in a group of participants to therapeutic processes for people with severe social disabilities http://www.medworm.com/index.php?rid=5493316&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F192 Conclusion: The outcomes of the study show that the homeless people examined presented with more psychopathological symptoms, in both axis II and axis IV, than the general population. This supports the need to take into account the comorbidity between these two types of disorder among homeless people, in treatment and in the development of specific intervention programs. In conclusion, the need for more psychosocial treatments addressing the individual problems of homeless people is supported. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5493316 Sun, 11 Dec 2011 05:00:00 +0100 5493316 General and Specific Components of Depression and Anxiety in an Adolescent Population http://www.medworm.com/index.php?rid=5484899&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F191 Conclusions: The general distress factor provides the most reliable target for epidemiological analysis but specific factors may help to refine valid phenotype dimensions for aetiological research and assist in prognostic modelling of future psychiatric episodes. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5484899 Wed, 07 Dec 2011 05:00:00 +0100 5484899 The working alliance in a randomized controlled trial comparing online with face-to-face cognitive-behavioral therapy for depression http://www.medworm.com/index.php?rid=5484901&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F189 Conclusions: Contrary to what might have been expected, the working alliance in the online group was comparable to that in the face-to-face group. However, the results showed no significant relations between the BDI residual gain score and the working alliance ratings in either group.Trial registration: ACTRN12611000563965 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5484901 Tue, 06 Dec 2011 05:00:00 +0100 5484901 Impact of geriatric comorbidity and polypharmacy on cholinesterase inhibitors prescribing in dementia http://www.medworm.com/index.php?rid=5484900&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F190 Conclusions: It seems that not age as such but the overall clinical condition of a patient including care dependency and geriatric comorbidities influences the process of decision making on prescription of ChEIs. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5484900 Tue, 06 Dec 2011 05:00:00 +0100 5484900 Reduced peak oxygen uptake and implications for cardiovascular health and quality of life in patients with schizophrenia http://www.medworm.com/index.php?rid=5474629&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F188 Background: Peak oxygen uptake (VO2peak) is a strong predictor of cardiovascular disease (CVD) and all-cause mortality, but is inadequately described in patients with schizophrenia. The aim of this study was to evaluate treadmill VO2peak, CVD risk factors and quality of life (QOL) in patients with schizophrenia (ICD-10, F20-29). Methods: 33 patients, 22 men (33.7+/-10.4 years) and 11 women (35.9+/-11.5 years), were included. Patients VO2peak were compared with normative VO2peak in healthy individuals from the Nord-Trondelag Health Study (HUNT). Risk factors were compared above and below the VO2peak thresholds; 44.2 and 35.1 ml x kg(-1) x min(-1) in men and women, respectively. Results: VO2peak was 37.1+/-9.2 ml x kg(-1) x min(-1) in men with schizophrenia; 74+/-19% of normative healthy men... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5474629 Mon, 05 Dec 2011 05:00:00 +0100 5474629 A randomized, controlled clinical trial: The effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized trial http://www.medworm.com/index.php?rid=5455324&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F187 DiscussionThis is a first randomized controlled trial that compare the effectiveness of MBCT with an active control, findings will advance current knowledge in the management of GAD and the way that group intervention can be delivered and inform future research.Unique Trail Number (assigned by Centre for Clinical Trails, Clinical Trials registry, The Chinese University of Hong Kong): CUHK_CCT00267 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5455324 Tue, 29 Nov 2011 05:00:00 +0100 5455324 REFOCUS Trial: protocol for a cluster randomised controlled trial of a pro-recovery intervention within community based mental health teams http://www.medworm.com/index.php?rid=5438999&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F185 DiscussionThis cluster-RCT will evaluate a pro-recovery intervention in community mental health teams. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5438999 Wed, 23 Nov 2011 05:00:00 +0100 5438999 Differences between patients' and clinicians' report of sleep disturbance: A field study in mental health care in Norway. http://www.medworm.com/index.php?rid=5438998&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F186 Conclusion: When patients meet the criteria for a mental disorder, insomnia is almost never diagnosed, and sleep disturbance is imprecisely recognized relative to the patients' experience of sleep disturbance. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5438998 Wed, 23 Nov 2011 05:00:00 +0100 5438998 Treatment and outcomes of crisis resolution teams: a prospective multicentre study http://www.medworm.com/index.php?rid=5439001&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F183 Conclusions: Our study indicates that, compared with the UK, the Norwegian CRTs provided less intensive and less out-of-office care. The Norwegian CRTs worked more with depression and suicidal crises than with psychoses. To be an alternative to hospital admission, the Norwegian CRTs need to intensify their treatment and meet more patients outside the office. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5439001 Tue, 22 Nov 2011 05:00:00 +0100 5439001 The Generalised Anxiety Stigma Scale (GASS): Psychometric properties in a community sample http://www.medworm.com/index.php?rid=5439000&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F184 Conclusions: The GASS is a promising brief measure of the stigma associated with Generalised Anxiety Disorder. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5439000 Tue, 22 Nov 2011 05:00:00 +0100 5439000 Supervised team management, with or without structured psychotherapy, in heavy users of a mental health service with borderline personality disorder: a two-year follow-up preliminary randomized study. http://www.medworm.com/index.php?rid=5439003&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F181 Conclusions: Although STM for BPD applied to heavy MHS users was effective in reducing symptoms and improving their global functioning, adding a time-limited and focused psychotherapy was found to achieve a better outcome. In particular, focusing treatment on patients' personality with a specific psychotherapeutic approach (i.e. SB-APP) seemed to be more effective than STM alone.Trial Registration: ClinicalTrials.gov: NCT1356069 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5439003 Mon, 21 Nov 2011 05:00:00 +0100 5439003 Report of depressive symptoms on waiting list and mortality after liver and kidney transplantation:a prospective cohort study http://www.medworm.com/index.php?rid=5439002&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F182 Conclusion: Further studies are needed to understand the underlying mechanisms of the association between report of depressive symptoms on waiting list and decreased risk of graft failure and mortality after transplantation. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5439002 Mon, 21 Nov 2011 05:00:00 +0100 5439002 Outcomes for depression and anxiety in primary care and details of treatment: a naturalistic longitudinal study http://www.medworm.com/index.php?rid=5419941&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F180 Conclusion: The added value of guideline-concordant care could not be demonstrated in this study. Symptom severity, employment status, social support and comorbidity of anxiety and depression play a role in poor clinical outcome(246 words) (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5419941 Fri, 18 Nov 2011 05:00:00 +0100 5419941 Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study http://www.medworm.com/index.php?rid=5419942&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F179 Conclusions: In AN, brain volume differences were found in appetitive, somatosensory and top-down control brain regions. Differences in regional GMV may be linked to levels of restraint, but whether they are state or trait is unclear. Nevertheless, these discrete brain volume differences provide candidate brain regions for further structural and functional study in people with eating disorders. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5419942 Thu, 17 Nov 2011 05:00:00 +0100 5419942 Use of Non-parametric Item Response Theory to develop a shortened version of the Positive and Negative Syndrome Scale (PANSS) http://www.medworm.com/index.php?rid=5419943&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F178 Conclusions: The study demonstrated the utility of non-parametric IRT in examining the item properties of the PANSS and to allow selection of items for an abbreviated PANSS scale. The comparisons between the 30-item PANSS and the Mini-PANSS revealed that the shorter version is comparable to the 30-item PANSS, but when applying IRT, the Mini-PANSS is also a good indicator of illness severity. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5419943 Wed, 16 Nov 2011 05:00:00 +0100 5419943 The Western Norway mental health interface study: a controlled intervention trial on referral letters between Primary Care and Specialist Mental Health Care http://www.medworm.com/index.php?rid=5405249&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F177 This study aims to explore if and to what degree the quality of referral letters within Mental Health Care for adults can be improved and the potential improvement's impact on defined patient, professional and organisational related outcomes.Methods and design: A controlled study with pre and post test will be prepared and accomplished to explore the correlation between the content of referral letters and outcomes of the care for the referred patients. The study is preformed in accordance with the guideline of the Medical Research Council on development and evaluation of complex interventions. Using a mixed method design, a stepwise model will be conducted: Firstly, process and outcome measures will be developed and tested. Secondly, by these measures, the results from an intervention grou... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5405249 Mon, 14 Nov 2011 05:00:00 +0100 5405249 Comparative efficacy and acceptability of methylphenidate and atomoxetine in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis http://www.medworm.com/index.php?rid=5398429&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F176 Background: Psychostimulants and non stimulants are effective in the treatment of ADHD. Efficacy of both methylphenidate and atomoxetine has been established in placebo controlled trials. Direct comparison of efficacy is now possible due to availability of results from several head-to-head trials of these two medications. Methods: All published, randomized, open label or double blind trials, comparing efficacy of methylphenidate with atomoxetine, in treatment of ADHD in children, diagnosed using DSM-IVTM criteria were included. The outcome studied was ADHDRS-IVParent:Inv score. The standardized mean difference (SMD) was used as a measure of effect size. Results: Nine randomized trials comparing methylphenidate and atomoxetine, with a total of 2762 participants were included. Meta-analysis ... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5398429 Thu, 10 Nov 2011 05:00:00 +0100 5398429 A randomized controlled pilot study of a brief web-based mindfulness training http://www.medworm.com/index.php?rid=5398430&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F175 Conclusion: This study of a brief web-based mindfulness training indicates that mindfulness can be taught online and may improve distress, perceived stress and negative affect for regular users. Although there were no significant improvements, but trends, for most measures under ITT, feasibility of such a program was demonstrated and also that persons continued to use techniques of the training in daily life.Trial RegistrationGerman Clinical Trials Register (DRKS): DRKS00003209 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5398430 Tue, 08 Nov 2011 05:00:00 +0100 5398430 Avoiding the 'twilight zone': Recommendations for the transition of services from adolescence to adulthood for young people with ADHD. http://www.medworm.com/index.php?rid=5378641&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F174 Attention deficit hyperactivity disorder (ADHD) is a common childhood disorder that frequently persists into adulthood. However, in the UK, there is a paucity of adult services available for the increasing number of young people with ADHD who are now graduating from child services. Furthermore, there is limited research investigating the transition of young people with ADHD from child to adult services and a lack of guidance on how to achieve this effectively. This paper reviews the difficulties of young people with ADHD and their families who are transitioning between services; we review transition from the child and adult health teams' perspectives and identify barriers to the transition process. We conclude with recommendations on how to develop transition services for young people with... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5378641 Thu, 03 Nov 2011 04:00:00 +0100 5378641 Adjunctive long-acting risperidone in patients with bipolar disorder who relapse frequently and have active mood symptoms http://www.medworm.com/index.php?rid=5357022&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F171 The objective of this exploratory analysis was to characterize efficacy and onset of action of a 3-month treatment period with risperidone long-acting injection (RLAI), adjunctive to an individual's treatment regimen, in subjects with symptomatic bipolar disorder who relapsed frequently and had significant symptoms of mania and/or depression. Methods: Subjects with bipolar disorder with [greater than or equal to]4 mood episodes in the past 12 months entered the open-label stabilization phase preceding a placebo-controlled, double-blind study. Subjects with significant depressive or manic/mixed symptoms at baseline were analyzed. Significant depressive symptoms were defined as Montgomery-Asberg Depression Rating Scale (MADRS) [greater than or equal to]16 and Young Mania Rating Scale (YMRS) ... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5357022 Fri, 28 Oct 2011 04:00:00 +0100 5357022 Assessing cognitive insight in nonpsychiatric individuals and outpatients with schizophrenia in Taiwan: An investigation using the Beck Cognitive Insight Scale http://www.medworm.com/index.php?rid=5345116&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F170 Conclusion: The BCIS proved to be useful for measuring cognitive insight in Taiwanese nonpsychiatric and psychotic populations.Key words: BCIS, cognitive insight, reliability, validity (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5345116 Fri, 21 Oct 2011 04:00:00 +0100 5345116 Assessment of Effectiveness Measures in Patients with Schizophrenia Initiated on Risperidone Long-acting Therapy: the SOURCE Study Results http://www.medworm.com/index.php?rid=5322404&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F167 Conclusion: The results suggest that treatment with RLAT may result in decreased hospitalizations for patients with schizophrenia.Trial RegistrationThis trial was registered with ClinicalTrials.gov with the identification number NCT00246194 (http://clinicaltrials.gov/ct2/show/NCT00246194). (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5322404 Fri, 14 Oct 2011 04:00:00 +0100 5322404 Resource Utilization in Patients With Schizophrenia Who Initiated Risperidone Long-acting Therapy: Results From the Schizophrenia Outcomes Utilization Relapse and Clinical Evaluation (SOURCE) http://www.medworm.com/index.php?rid=5322403&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F168 Conclusion: The results suggest that treatment with RLAT may result in decreased hospitalizations for patients with schizophrenia.Trial RegistrationThis trial was registered with ClinicalTrials.gov with the identification number NCT00246194 (http://clinicaltrials.gov/ct2/show/NCT00246194). (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5322403 Fri, 14 Oct 2011 04:00:00 +0100 5322403 Do general practitioners and psychiatrists agree about defining cure from depression? The DEsCRIBE(TM) survey http://www.medworm.com/index.php?rid=5322402&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F169 Conclusions: Belgian GPs and psychiatrists strongly agreed on which criteria were important in defining cure from depression but differed in their attitudes about depression. The outcome dimensions that were considered important in defining cure were influenced by physicians' attitudes - this was more pronounced in GPs than in psychiatrists. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5322402 Fri, 14 Oct 2011 04:00:00 +0100 5322402 A study of a culturally focused psychiatric consultation service for Asian American and Latino American primary care patients with depression http://www.medworm.com/index.php?rid=5312352&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F166 DiscussionThe study involves an innovative yet practical intervention that builds on existing resources and strives to improve quality of care for depression for minorities. Additionally, it complements the current movement in psychiatry to enhance the treatment of depression in primary care settings. If found beneficial, the intervention will serve as a model for care of Asian American and Latino American patients.Trial Registration: Clinicaltrials.gov identifier NCT01239407 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5312352 Thu, 13 Oct 2011 04:00:00 +0100 5312352 The impact of mental illness on potentially preventable hospitalisations: a population-based cohort study http://www.medworm.com/index.php?rid=5302664&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F163 Conclusions: MHCs have a significantly higher rate of PPHs than non-MHCs. Improving primary and secondary prevention is warranted in MHCs, especially at the primary care level, despite there may be different thresholds for admission in people with established physical disease that is influenced by whether or not they have comorbid mental illness. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5302664 Mon, 10 Oct 2011 04:00:00 +0100 5302664 Sub-threshold depression and antidepressants use in a community sample: searching anxiety and finding bipolar disorder http://www.medworm.com/index.php?rid=5302663&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F164 Conclusions: This study suggests caution in prescribing ADs to people with SD. In people with concomitant anxiety disorders and SD, it should be mandatory to perform a well-designed assessment and evaluate the presence of previous manic or hypomanic symptoms prior to prescribing ADs. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5302663 Mon, 10 Oct 2011 04:00:00 +0100 5302663 Five-year mortality in a cohort of people with schizophrenia in Ethiopia. http://www.medworm.com/index.php?rid=5302662&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F165 Conclusion: The alarmingly high mortality observed in this patient population is of major concern. Most patients died from potentially treatable conditions. Improving medical and psychiatric care as well as provision of basic needs is recommended. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5302662 Mon, 10 Oct 2011 04:00:00 +0100 5302662 Cognitive flexibility in verbal and nonverbal domains and decision making in anorexia nervosa patients: a pilot study. http://www.medworm.com/index.php?rid=5294985&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F162 Conclusions: These data provide evidence that patients with AN-R have cognitive rigidity in both verbal and non-verbal domains. The role of the impairment on verbal domains should be considered in treatment. Further research is warranted to better understand the relationship between illness state and cognitive rigidity and impaired decision-making. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5294985 Fri, 07 Oct 2011 04:00:00 +0100 5294985 Prolonged-release melatonin versus placebo for benzodiazepine discontinuation in patients with schizophrenia: a randomized clinical trial - the SMART trial protocol http://www.medworm.com/index.php?rid=5294987&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F160 DiscussionThe results from this trial will examine whether melatonin has a role in withdrawing long-term benzodiazepine administration in schizophrenia patients. This group of patients is difficult to treat and therefore often subject to polypharmacy which may play a role in the reduced life expectancy of patients compared to the background population. The results will also provide new information on the association of chronic benzodiazepine treatment with sleep, psychophysiology, cognition, social function, and quality of life. Knowledge of these important clinical aspects is lacking in this group of patients.Trial Registration: ClinicalTrials NCT01431092 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5294987 Wed, 05 Oct 2011 04:00:00 +0100 5294987 REFLEX: a social-cognitive group treatment to improve insight in schizophrenia: study protocol of a multi-center RCT http://www.medworm.com/index.php?rid=5294986&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F161 DiscussionREFLEX is one of the few interventions aiming specifically to improving insight in schizophrenia and has potential value for improving insight in schizophrenia. Targeting insight in schizophrenia is a complex task, that comes with several methodological issues. These issues are addressed in the discussion of this paper. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5294986 Wed, 05 Oct 2011 04:00:00 +0100 5294986 Obesity and nutrition behaviours in Western and Palestinian outpatients with severe mental illness http://www.medworm.com/index.php?rid=5283089&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F159 Conclusion: Patients with mental illness have poorer nutritional habits than the general population, particularly in Western nations. Separate interventions to improve nutritional habits and reduce obesity are warranted between Western nations and Palestine. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5283089 Tue, 04 Oct 2011 04:00:00 +0100 5283089 COMMAND: a multi-centre, randomised controlled trial of cognitive therapy to prevent harmful compliance with command hallucinations http://www.medworm.com/index.php?rid=5271319&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F155 DiscussionCognitive behaviour therapy is recommended for people with psychosis; however, its focus and evaluation has primarily revolved around the reduction of psychotic symptoms. In this trial, however, the focus of the cognitive behavioural intervention is on individuals' appraisals, behaviour and affect and not necessarily symptoms; this is also reflected in the outcome measures used. If successful, the results will mark a significant breakthrough in the evidence base for service users and clinicians and will provide a treatment option for this group where none currently exist. The trial will open the way for further breakthrough work with the 'high risk' population of individuals with psychosis, which we would intend to pursue.Trial RegistrationISRCTN62304114 (Source: BMC Psychiatry -... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5271319 Fri, 30 Sep 2011 04:00:00 +0100 5271319 The effectiveness of problem solving therapy in deprived South African communities: results from a pilot study http://www.medworm.com/index.php?rid=5271318&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F156 Conclusions: The results suggest that brief problem solving in a booklet/workshop format may be an effective, feasible and acceptable short-term treatment for people with CMD's in deprived communities. In this setting, group delivery of PST had lower drop-out rates than individual delivery, and was more feasible and acceptable. Randomized controlled trials are needed to evaluate the effect of brief self-help PST more rigorously. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5271318 Fri, 30 Sep 2011 04:00:00 +0100 5271318 Service user and carer experiences of seeking help for a first episode of psychosis: a UK qualitative study http://www.medworm.com/index.php?rid=5271317&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F157 Conclusion: Even modest periods of untreated psychosis cause distress and disruption to individuals and their families. Early intervention services should prioritise early detection. Initiatives aimed at reducing DUP may succeed not by promoting swift service response alone, but also by targeting delays in initial help-seeking. Our study suggests that strategies for doing this may include addressing the stigma associated with psychosis and community education regarding symptoms and services, targeting not only young people developing illness but also a range of people in their networks, including staff in educational and community organisations. Initiatives to enhance the effective involvement of staff in community organisations working with young people in promoting help-seeking merit res... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5271317 Fri, 30 Sep 2011 04:00:00 +0100 5271317 ADHD in adolescents with borderline personality disorder http://www.medworm.com/index.php?rid=5271316&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F158 Conclusions: Comorbid ADHD influences the clinical presentation of adolescents with BPD and is associated with higher rates of ODD, other cluster B personality disorders, and cognitive impulsiveness. A subgroup of BPD patients may exhibit developmentally driven impairments of the inhibitory system persisting since childhood. Specific interventions should be recommended for this subsample of BPD adolescents. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5271316 Fri, 30 Sep 2011 04:00:00 +0100 5271316 A study of the effectiveness of telepsychiatry-based culturally sensitive collaborative treatment of depressed Chinese Americans http://www.medworm.com/index.php?rid=5258419&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F154 DiscussionThe study investigates the T-CSCT model, which we believe will increase the feasibility and practicality of the CSCT model by adopting telemedicine technology. We anticipate that this model will expand access to culturally competent psychiatrists fluent in patients' native languages to improve treatment of depressed minority patients in primary care settings.Trial Registration NCT00854542 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5258419 Mon, 26 Sep 2011 04:00:00 +0100 5258419 Early response predicts subsequent response to olanzapine long-acting injection in a randomized, double-blind clinical trial of treatment for schizophrenia http://www.medworm.com/index.php?rid=5247856&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F152 Conclusions: Among acutely ill patients with schizophrenia, early response predicted subsequent response to olanzapine LAI. Early Responders experienced significantly better clinical and functional outcomes than Early Non-responders. Findings are consistent with previous research on oral antipsychotics.Clinical Trials RegistryF1D-MC-HGJZ: Comparison of Intramuscular Olanzapine Depot With Placebo in the Treatment of Patients With Schizophreniahttp://clinicaltrials.gov/ct2/show/NCT00088478?term=olanzapine+depot&rank=3Registry identifier - NCT00088478 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5247856 Fri, 23 Sep 2011 04:00:00 +0100 5247856 No association between COMT val158met polymorphism and suicidal behavior: Meta-analysis and new data http://www.medworm.com/index.php?rid=5247857&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F151 Conclusion: Our results showed no association between COMTval158/met and suicidal behavior. However, more studies are necessary to determine an association between COMT and suicidal behavior. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5247857 Wed, 21 Sep 2011 04:00:00 +0100 5247857 Early reduction in painful physical symptoms is associated with improvements in long-term depression outcomes in patients treated with duloxetine http://www.medworm.com/index.php?rid=5235695&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F150 Conclusion: Pain reduction after 2 and 4 weeks can be used to estimate outcomes of long-term treatment with duloxetine. PPS associated with depression have a potential role in predicting remission of depressive symptoms in clinical practice. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5235695 Tue, 20 Sep 2011 04:00:00 +0100 5235695 The prediction of discharge from in-patient psychiatric rehabilitation: a case-control study. http://www.medworm.com/index.php?rid=5235696&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F149 Conclusions: People admitted later in the study period required longer rehabilitation admissions and had higher rates of serious self harm and treatment resistant illness. They were also more likely to have had previous contact with forensic services. This change over time is likely to be due to the drive in Scotland to manage mentally disordered offenders in conditions of lower security. There is a growing need for secure longer-term in-patient rehabilitation, particularly for people previously treated in forensic services. Admission to rehabilitation earlier in a person's illness may improve their outcome. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5235696 Fri, 16 Sep 2011 04:00:00 +0100 5235696 A pattern of Cerebral Perfusion Anomalies between Major Depressive Disorder and Hashimoto Thyroiditis http://www.medworm.com/index.php?rid=5220976&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F148 This study aims to evaluate relationship between three different clinical conditions: Major Depressive Disorders (MDD), Hashimoto Thyroiditis (HT) and reduction in regional Cerebral Blood Flow (rCBF) in order to explore the possibility that patients with HT and MDD have specific pattern(s) of cerebral perfusion. Methods: Design: Analysis of data derived from two separate data banks.Sample: 54 subjects, 32 with HT (29 women, mean age 38.8+/-13.9); 22 without HT (19 women, mean age 36.5+/-12.25).Assessment: Psychiatric diagnosis was carried out by Simplified Composite International Diagnostic Interview (CIDIS) using DSM-IV categories; cerebral perfusion was measured by 99mTc-ECD SPECT. Statistical analysis was done through logistic regression. Results: MDD appears to be associated with left ... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5220976 Tue, 13 Sep 2011 04:00:00 +0100 5220976 A prospective study of mental health care for comorbid depressed mood in older adults with painful osteoarthritis http://www.medworm.com/index.php?rid=5220977&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F147 Background: Comorbid depression is common among adults with painful osteoarthritis (OA). We evaluated the relationship between depressed mood and receipt of mental health (MH) care services. Methods: In a cohort with OA, annual interviews assessed comorbidity, arthritis severity, and MH (SF-36 mental health score). Surveys were linked to administrative health databases to identify mental health-related visits to physicians in the two years following the baseline interview (1996-98). Prescriptions for anti-depressants were ascertained for participants aged 65+ years (eligible for drug benefits). The relationship between MH scores and MH-related physician visits was assessed using zero-inflated negative binomial regression, adjusting for confounders. For those aged 65+ years, logistic regres... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5220977 Mon, 12 Sep 2011 04:00:00 +0100 5220977 Supplier-induced demand for psychiatric admissions in Northern New England http://www.medworm.com/index.php?rid=5205614&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F146 Conclusions: The positive correlation between admission and bed supply suggests that psychiatric bed availability may partially explain the variation in admission rates. Development of PHSAs, rather than relying on the use of established general medical HSAs, improves the relevance and accuracy of small area analysis in understanding mental health services utilization. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5205614 Fri, 09 Sep 2011 04:00:00 +0100 5205614 Anti-depressive effectiveness of olanzapine, quetiapine, risperidone and ziprasidone: a pragmatic, randomized trial. http://www.medworm.com/index.php?rid=5181474&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F145 Background: Efficacy studies indicate anti-depressive effects of at least some second generation antipsychotics (SGAs). The Bergen Psychosis Project (BPP) is a 24-month, pragmatic, industry-independent, randomized, head-to-head comparison of olanzapine, quetiapine, risperidone and ziprasidone in patients acutely admitted with psychosis. The aim of the study is to investigate whether differential anti-depressive effectiveness exists among SGAs in a clinically relevant sample of patients acutely admitted with psychosis. Methods: Adult patients acutely admitted to an emergency ward for psychosis were randomized to olanzapine, quetiapine, risperidone or ziprasidone and followed for up to 2 years. Participants were assessed repeatedly using the Positive and Negative Syndrome Scale - Depression ... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5181474 Tue, 30 Aug 2011 23:00:00 +0100 5181474 Massively Multiplayer Online RolePlaying Games: Comparing characteristics of addict vs non-addict online recruited gamers in a French adult population http://www.medworm.com/index.php?rid=5169424&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F144 Conclusions: The DAS appeared to be a good first-line instrument to screen MMORPG addiction in online gamers. This study found high MMORPG addiction rates, and self-reported adverse symptoms in important aspects of life, including mood and sleep. This confirms the need to set up relevant prevention programs against online game overuse. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5169424 Thu, 25 Aug 2011 23:00:00 +0100 5169424 Sustained favorable long-term outcome in the treatment of schizophrenia: a 3-year prospective observational study http://www.medworm.com/index.php?rid=5158465&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F143 Conclusions: Only a small percentage of patients achieved sustained favorable long-term outcome in this study, suggesting there continues to be a great need for improvement in the treatment of schizophrenia. Findings suggest that clinicians could make early projections of health states and identify those patients more likely to achieve favorable long-term outcomes enabling early therapeutic interventions to enhance benefits for patients. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158465 Thu, 25 Aug 2011 23:00:00 +0100 5158465 The Relaxation Exercise and Social Support Trial-RESST: Study protocol for a randomized community based trial http://www.medworm.com/index.php?rid=5158466&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F142 Discussion: The results will indicate whether the proposed psychosocial intervention was effective in reducing MUVD (possibly mediated by common mental distress).Trial Registration: The trial is registered at the Wellcome Trust Registry, ISRCTN assigned: ISRCTN98441241 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158466 Wed, 24 Aug 2011 23:00:00 +0100 5158466 Dimensionality and scale properties of the Edinburgh Depression Scale (EDS) in patients with type 2 diabetes mellitus: The DiaDDZOB Study http://www.medworm.com/index.php?rid=5158467&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F141 Conclusions: The EDS constitutes a sound scale for measuring an attribute of general depression. Persons can be reliably measured using the sum score. Screening rules for mild and severe depression are applicable to both males and females. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158467 Tue, 23 Aug 2011 23:00:00 +0100 5158467 Long term life dissatisfaction and subsequent major depressive disorder and poor mental health http://www.medworm.com/index.php?rid=5158468&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F140 Conclusions: The life satisfaction burden is significantly related to major depressive disorder and poor mental health, both in cross-sectional and longitudinal settings.Keywordslife satisfaction, quality of life, major depressive disorder, hopelessness. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158468 Mon, 22 Aug 2011 23:00:00 +0100 5158468 Patterns of Treatment Seeking Behavior for Mental Illnesses in Southwest Ethiopia: A Hospital Based Study http://www.medworm.com/index.php?rid=5158470&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F138 Conclusions: There is significant delay in modern psychiatric treatment seeking in the majority of the cases. Traditional healers were the first place where help was sought for mental illness in this population. Most of the respondents claimed that mental illnesses were caused by supernatural factors. In contrast to their thoughts about the causes of mental illnesses however, most of the respondents believed that mental illnesses could be cured with biomedical treatment. Interventions targeted at improving public awareness about the causes and treatment of mental illness could reduce the delay in treatment seeking and improve treatment outcomes.Key words: 'mental illness', 'treatment seeking', 'pathways to care', 'Ethiopia' (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158470 Sun, 21 Aug 2011 23:00:00 +0100 5158470 A systematic review and meta-analysis of neurological soft signs in relatives of people with schizophrenia http://www.medworm.com/index.php?rid=5158469&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F139 Conclusions: Both hypotheses were confirmed, suggesting that the distribution of neurological soft signs in people with schizophrenia and their first-degree relatives is consistent with the endophenotype criterion of familial association. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158469 Sun, 21 Aug 2011 23:00:00 +0100 5158469 Cocaine Addiction Treatments to improve Control and reduce Harm (CATCH): New Pharmacological Treatment Options for Crack-Cocaine Dependence in the Netherlands http://www.medworm.com/index.php?rid=5158473&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F135 DiscussionTo date, the CATCH-study is the first study in the Netherlands that explores new treatment options for crack-cocaine dependence focusing on both abstinence and harm minimisation. It is expected that the study will contribute to the development of new treatments for one of the most problematic substance use disorders.Trial RegistrationThe Netherlands National Trial Register NTR2576The European Union Drug Regulating Authorities Clinical Trials EudraCT2009-010584-16 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158473 Thu, 18 Aug 2011 23:00:00 +0100 5158473 Self-esteem is associated with premorbid adjustment and positive psychotic symptoms in early psychosis. http://www.medworm.com/index.php?rid=5158472&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F136 Conclusion: There are reasons to suspect that premorbid functioning is an important aspect in the development of self- esteem, and, furthermore, that self-esteem is associated with the development of delusions and hallucinations. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158472 Thu, 18 Aug 2011 23:00:00 +0100 5158472 Signs and symptoms of acute mania: a factor analysis http://www.medworm.com/index.php?rid=5158471&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F137 Conclusions: Our findings identified three clinically meaningful factors corresponding to 'elated mania', 'irritable mania' and 'psychotic mania'. These findings support the multidimensional nature of manic symptoms. Further evidence is needed to support the existence of corresponding clinical subtypes. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5158471 Thu, 18 Aug 2011 23:00:00 +0100 5158471 Collaborative Care for Patients with Bipolar Disorder: a randomised controlled trial http://www.medworm.com/index.php?rid=5138500&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F133 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5138500 Tue, 16 Aug 2011 23:00:00 +0100 5138500 Comparative efficacy of the Cognitive Behavioral Analysis System of Psychotherapy versus Supportive Psychotherapy for early onset chronic depression: design and rationale of a multisite randomized controlled trial http://www.medworm.com/index.php?rid=5138499&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F134 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5138499 Tue, 16 Aug 2011 23:00:00 +0100 5138499 Attenuating posttraumatic distress with omega-3 polyunsaturated fatty acids among disaster medical assistance team members after the Great East Japan Earthquake: The APOP randomized controlled trial http://www.medworm.com/index.php?rid=5138501&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F132 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5138501 Mon, 15 Aug 2011 23:00:00 +0100 5138501 Meta-review of the effectiveness of Computerised CBT in treating depression http://www.medworm.com/index.php?rid=5125631&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F131 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5125631 Thu, 11 Aug 2011 23:00:00 +0100 5125631 Waist Circumference, Abdominal Obesity, and Depression among Overweight and Obese U.S. Adults: National Health and Nutrition Examination Survey 2005-2006 http://www.medworm.com/index.php?rid=5118462&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F130 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5118462 Wed, 10 Aug 2011 23:00:00 +0100 5118462 The Obsessive-Compulsive Inventory-Revised Scale: Replication and extension to non-clinical and clinical individuals with OCD symptoms http://www.medworm.com/index.php?rid=5107255&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F129 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5107255 Sun, 07 Aug 2011 23:00:00 +0100 5107255 Validation of cross-cultural child mental health and psychosocial research instruments: adapting the Depression Self-Rating Scale and Child PTSD Symptom Scale in Nepal http://www.medworm.com/index.php?rid=5095690&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F127 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5095690 Wed, 03 Aug 2011 23:00:00 +0100 5095690 Internet-based cognitive behavior therapy for obsessive compulsive disorder: A pilot study http://www.medworm.com/index.php?rid=5095692&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F125 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5095692 Tue, 02 Aug 2011 23:00:00 +0100 5095692 Previous hospital admissions and disease severity predicts the use of antipsychotic combination treatment in patients with schizophrenia http://www.medworm.com/index.php?rid=5095691&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F126 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5095691 Tue, 02 Aug 2011 23:00:00 +0100 5095691 Decreased glutathione levels and impaired antioxidant enzyme activities in drug-naive first-episode schizophrenic patients http://www.medworm.com/index.php?rid=5095693&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F124 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5095693 Mon, 01 Aug 2011 23:00:00 +0100 5095693 Early effect of NEURAPAS(R) balance on current source density (CSD) of human EEG http://www.medworm.com/index.php?rid=5086021&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F123 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5086021 Mon, 01 Aug 2011 23:00:00 +0100 5086021 Preliminary study of relationships between hypnotic susceptibility and personality disorder functioning styles in healthy volunteers and personality disorder patients http://www.medworm.com/index.php?rid=5086023&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F121 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5086023 Fri, 29 Jul 2011 23:00:00 +0100 5086023 Substance Abuse and Psychiatric Co-morbidity as Predictors of Premature Mortality in Swedish Drug Abusers: A Prospective Longitudinal Study 1970 - 2006 http://www.medworm.com/index.php?rid=5086022&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F122 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5086022 Fri, 29 Jul 2011 23:00:00 +0100 5086022 Does psychopathology at admission predict the length of inpatient stay in psychiatry? Implications for financing psychiatric services http://www.medworm.com/index.php?rid=5077460&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F120 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5077460 Thu, 28 Jul 2011 23:00:00 +0100 5077460 Communication patterns in a psychotherapy following traumatic brain injury: A quantitative study based on symbolic dynamics http://www.medworm.com/index.php?rid=5069250&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F119 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5069250 Tue, 26 Jul 2011 23:00:00 +0100 5069250 Rapid Progress or Lengthy Process? Electronic Personal Health Records in Mental Health http://www.medworm.com/index.php?rid=5069252&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F117 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5069252 Mon, 25 Jul 2011 23:00:00 +0100 5069252 Is antipsychotic polypharmacy associated with metabolic syndrome even after adjustment for lifestyle effects? : a cross-sectional study http://www.medworm.com/index.php?rid=5069251&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F118 Antipsychotic polypharmacy, compared with monotherapy in outpatients with schizophrenia, may be independently associated with an increased risk of having pre-metabolic syndrome, even after adjusting for patients’ lifestyle characteristics. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5069251 Mon, 25 Jul 2011 23:00:00 +0100 5069251 Cognitive Behaviour Therapy in Medication-Treated Adults with ADHD and Persistent Symptoms: A randomized controlled trial. http://www.medworm.com/index.php?rid=5062005&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F116 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5062005 Sun, 24 Jul 2011 23:00:00 +0100 5062005 Exercise augmentation compared to usual care for Post Traumatic Stress Disorder: A Randomised Controlled Trial (The REAP study: Randomised Exercise Augmentation for PTSD) http://www.medworm.com/index.php?rid=5050189&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F115 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5050189 Thu, 21 Jul 2011 23:00:00 +0100 5050189 Pragmatic randomised controlled trial of group psychoeducation versus group support in the maintenance of bipolar disorder. http://www.medworm.com/index.php?rid=5050190&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F114 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5050190 Wed, 20 Jul 2011 23:00:00 +0100 5050190 Is the PANSS used correctly? A systematic review http://www.medworm.com/index.php?rid=5050191&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F113 ${item.shortDescription} (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5050191 Sun, 17 Jul 2011 23:00:00 +0100 5050191 Risk of malnutrition is associated with mental health symptoms in community living elderly men and women: The Tromsoe Study http://www.medworm.com/index.php?rid=5036096&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F112 Background: Little research has been done on the relationship between malnutrition and mental health in community living elderly individuals. In the present study, we aimed to assess the associations between mental health (particularly anxiety and depression) and both the risk of malnutrition and body mass index (BMI, kg/m2) in a large sample of elderly men and women from Tromsoe, Norway. Methods: In a cross-sectional survey, with 1558 men and 1553 women aged 65 to 87 years, the risk of malnutrition was assessed by the Malnutrition Universal Screening Tool ('MUST'), and mental health was measured by the Symptoms Check List 10 (SCL-10). BMI was categorised into six groups ( (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5036096 Sat, 16 Jul 2011 23:00:00 +0100 5036096 The elderly in the psychiatric emergency service (PES); a descriptive study. http://www.medworm.com/index.php?rid=5036097&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F111 Conclusion: Although no proportional increase in PES use over time was found the elderly do possess distinct characteristics potentially useful in PES resource planning so as to better serve this increasingly important segment of the general population. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5036097 Thu, 14 Jul 2011 23:00:00 +0100 5036097 European youth care sites serve different populations of adolescents with cannabis use disorder. Baseline and referral data from the INCANT trial http://www.medworm.com/index.php?rid=5019140&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F110 Conclusions: A multisite trial has the advantage of being efficient, but it also carries risks, the most important one being lack of equivalence between local study populations. Our site populations differed in many respects. This is not a problem for analyses and interpretations if the differences somehow can be accounted for. To a major extent, this appeared possible in INCANT. The most important factor underlying the cross-site variations in baseline characteristics was referral source. Correcting for referral source made most differences disappear. Therefore, we will use referral source as a covariate accounting for site differences in future INCANT outcome analyses.Trial registrationISRCTN51014277 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5019140 Mon, 11 Jul 2011 23:00:00 +0100 5019140 Profiles of Family-focused Adverse Experiences through Childhood and Early Adolescence: The ROOTS Project, a community investigation of adolescent mental health http://www.medworm.com/index.php?rid=5007815&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F109 Conclusions: Family adversities in the early years occur as multiple rather than single experiences. Although some children escape adversity, for many this negative family environment persists over the first 15 years of life. Different profiles of family risk may be associated with specific mental disorders in young people. Sex differences in psychopathologies may be most pronounced in those exposed to low levels of family adversities. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=5007815 Wed, 06 Jul 2011 23:00:00 +0100 5007815 Subjective memory complaints, vascular risk factors and psychological distress in the middle-aged: a cross-sectional study http://www.medworm.com/index.php?rid=4992481&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F108 Conclusions: In a large sample of middle-aged people without any history of major affective illness or stroke, psychological distress was strongly, and vascular risk factors only weakly, associated with SMC, although we cannot discount psychological distress acting as a mediator in any association between vascular risk factors and SMC. Given this, clinicians should be vigilant regarding the presence of an affective illness when assessing middle-aged patients presenting with memory problems. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4992481 Thu, 30 Jun 2011 23:00:00 +0100 4992481 Experiences of guided Internet-based cognitive-behavioural treatment for depression: A qualitative study http://www.medworm.com/index.php?rid=4984236&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F107 Conclusions: We conclude that the findings correspond with existing theoretical models of face-to-face psychotherapy within qualitative process research. Persons who take responsibility for the treatment and also attribute success to themselves appear to benefit more. Motivation is a crucial aspect of guided self-help in the treatment of depression. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4984236 Wed, 29 Jun 2011 23:00:00 +0100 4984236 A cross-sectional testing of The Iowa Personality Disorder Screen in a psychiatric outpatient setting http://www.medworm.com/index.php?rid=4975589&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F105 Conclusion: Our results support the IPDS as a useful screening instrument for PDs present or absent in the POC setting. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4975589 Mon, 27 Jun 2011 23:00:00 +0100 4975589 Collaborative Care for patients with severe borderline and NOS personality disorders: A comparative multiple case study on processes and outcomes. http://www.medworm.com/index.php?rid=4968333&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F102 DiscussionThe present study is, as to the best of our knowledge, the first to examine Collaborative Care for patients with severe personality disorders receiving outpatient mental health care. With the chosen design we want to examine how and which elements of the CC Program could contribute to a better quality of life for the patients.Trial registration: Dutch Trial Register NTR2763 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4968333 Thu, 23 Jun 2011 23:00:00 +0100 4968333 Is Ankyrin a genetic risk factor for psychiatric phenotypes? http://www.medworm.com/index.php?rid=4968332&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F103 Conclusion: Our results support a specific genetic contribution of ANK3 to bipolar disorder though we failed to replicate findings for schizophrenia. We cannot confirm ANK3 as a common risk factor for different diseases. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4968332 Thu, 23 Jun 2011 23:00:00 +0100 4968332 Physical health behaviours and health locus of control in people with schizophrenia-spectrum disorder and bipolar disorder: a cross-sectional comparative study with people with non-psychotic mental illness http://www.medworm.com/index.php?rid=4968331&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F104 Background: People with mental illness experience high levels of morbidity and mortality from physical disease compared to the general population. Our primary aim was to compare how people with severe mental illness (SMI; i.e. schizophrenia-spectrum disorders and bipolar disorder) and non-psychotic mental illness perceive their: (i) global physical health, (ii) barriers to improving physical health, (iii) physical health with respect to important aspects of life and (iv) motivation to change modifiable high-risk behaviours associated with coronary heart disease. A secondary aim was to determine health locus of control in these two groups of participants. Methods: People with SMI and non-psychotic mental illness were recruited from an out-patient adult mental health service in London. Cross... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4968331 Thu, 23 Jun 2011 23:00:00 +0100 4968331 Effects of asenapine on depressive symptoms in patients with bipolar I disorder experiencing acute manic or mixed episodes: A post hoc analysis of two 3-week clinical trials http://www.medworm.com/index.php?rid=4952578&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F101 Conclusions: These post hoc analyses show that asenapine reduced depressive symptoms in bipolar I disorder patients experiencing acute manic or mixed episodes with clinically relevant depressive symptoms at baseline; olanzapine results appeared to be less consistent. Controlled studies of asenapine in patients with acute bipolar depression are necessary to confirm the generalizability of these findings. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4952578 Sun, 19 Jun 2011 23:00:00 +0100 4952578 Relatives Education And Coping Toolkit - REACT. Study protocol of a randomised controlled trial to assess the feasibility and effectiveness of a supported self management package for relatives of people with recent onset psychosis http://www.medworm.com/index.php?rid=4933747&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F100 DiscussionThe intervention is compared to current treatment in a sample of participants highly representative of relatives in routine early intervention services across the UK. The intervention is protocolised, offered within routine practice by existing staff and extensive process data is being collected. Randomisation is independent. All assessments are made by blind raters. The limitations of the study are the lack of control over how the intervention is delivered, the short follow-up period, and the lack of assessment of service user outcomes. Despite these, the findings will inform future effectiveness trials and contribute to the growing evidence base for supported self-mangement interventions in mental health. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4933747 Wed, 15 Jun 2011 23:00:00 +0100 4933747 CHAMP: Cognitive behaviour therapy for health anxiety in medical patients: a randomised controlled trial http://www.medworm.com/index.php?rid=4933748&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F99 DiscussionThis represents the first trial of adapted cognitive behaviour therapy in health anxiety that is large enough to test not only the clinical benefits of treatment but also whether the cost of treatment is offset by savings from reduced use of other health services in comparison to the control group.Cognitive behaviour therapy for Health Anxiety in Medical Patients (CHAMP)Trial registrationCurrent Controlled Trials ISRCTN14565822 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4933748 Mon, 13 Jun 2011 23:00:00 +0100 4933748 Distress related to myocardial infarction and cardiovascular outcome: a retrospective observational study http://www.medworm.com/index.php?rid=4921200&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F98 Conclusions: Retrospectively perceived MI-related distress in the form of fear of dying, helplessness, or pain was associated with non-fatal cardiovascular outcome independent of other important prognostic factors. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4921200 Thu, 09 Jun 2011 23:00:00 +0100 4921200 Prevalence of severe mental distress and its correlates in a population-based study in rural south-west Uganda http://www.medworm.com/index.php?rid=4911265&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F97 Conclusion: SMD in this study was associated with both socio-demographic and behavioural factors. The association between SMD and high risk sexual behaviour calls for the integration of HIV prevention in mental health care programmes in high HIV prevalence settings. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4911265 Tue, 07 Jun 2011 23:00:00 +0100 4911265 Major depressive disorder following terrorist attacks: A systematic review of prevalence, course and correlates http://www.medworm.com/index.php?rid=4892489&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F96 Conclusions: Methodological limitations in the literature of this field are considered and potentially important areas for future research such as the assessment of the course of MDD, the study of correlates of MDD or the comorbidity between MDD and other mental health problems are discussed. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4892489 Tue, 31 May 2011 23:00:00 +0100 4892489 Treating Postnatal Depressive Symptoms in Primary Care: A Randomised Controlled Trial of GP Management, with and without Adjunctive Counselling http://www.medworm.com/index.php?rid=4871918&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F95 Conclusions: Data from this small study suggest that GP management of PND when augmented by a CBT-counselling package may be successful in reducing depressive symptoms in more patients compared to GP management alone. The relatively low rates of referral and treatment uptake, suggest that help-seeking remains an issue for many women with PND, consistent with previous research. The study is registered at ClinicalTrials.gov, Trial Registration Number NCT01002027. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4871918 Thu, 26 May 2011 23:00:00 +0100 4871918 A cross-sectional study of patients with and without substance use disorders in Community Mental Health Centres http://www.medworm.com/index.php?rid=4852733&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F93 Conclusion: CMHCs need to implement systematic screening and diagnostic procedures in order to detect the special needs of these patients and improve their treatment. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4852733 Sun, 22 May 2011 23:00:00 +0100 4852733 Translation and validation of the Korean confusion assessment method for the intensive care unit http://www.medworm.com/index.php?rid=4852732&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F94 Conclusions: The Korean CAM-ICU showed good validity and could be incorporated into clinical practice in Korean ICUs.Trial registration: Current Controlled Trials ISRCTN50265663 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4852732 Sun, 22 May 2011 23:00:00 +0100 4852732 Act In case of Depression: The evaluation of a care program to improve the detection and treatment of depression in nursing homes. Study Protocol http://www.medworm.com/index.php?rid=4847816&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F91 DiscussionThe care program is expected to be effective in reducing the frequency of depression and in increasing the quality of life of residents. The study will further provide insight in the cost-effectiveness of the care program.Trial registration: The Netherlands National Trial Register (NTR). Trial number: NTR1477 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4847816 Thu, 19 May 2011 23:00:00 +0100 4847816 Psychological treatment of depressive symptoms in Chinese elderly inpatients with significant medical comorbidity: A meta-analysis http://www.medworm.com/index.php?rid=4847815&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F92 Conclusions: We conclude that psychological treatments of depressive symptoms are effective for Chinese elderly inpatients with significant medical comorbidity which should receive more attention in medical settings. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4847815 Thu, 19 May 2011 23:00:00 +0100 4847815 Benzodiazepine Use and Misuse among Patients in a Methadone Program http://www.medworm.com/index.php?rid=4841155&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F90 Conclusions: : Important information on epidemiology of BZD misuse among methadone-maintenance patients suggests that most methadone programs do not address co-occurring anxiety problems, and methadone treatment may trigger onset or worsening of BZD misuse. Further study is needed to explore how to curb misuse and abuse of BZD in the addiction population, and provide effective treatments targeting simultaneously addiction symptoms, anxiety disorders and BZD misuse. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4841155 Wed, 18 May 2011 23:00:00 +0100 4841155 Explicit and implicit information needs of people with depression: A qualitative investigation of problems reported on an online depression support forum http://www.medworm.com/index.php?rid=4841157&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F88 Conclusions: People with depression have substantial unmet information needs and require strategies to deal with the difficulties they face. They require access to high quality and relevant online resources and professionals; thus, there is a need to rectify current gaps in the provision of information and limitations of dissemination. Greater knowledge about depression and its treatment is also needed at the general community level. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4841157 Tue, 17 May 2011 23:00:00 +0100 4841157 The patient perspective in research on major depression http://www.medworm.com/index.php?rid=4841156&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F89 Although thousands of studies have examined the genetics, epidemiology, etiology, biology, treatment and prevention of major depressive disorder, we still lack very basic knowledge about what patients with depressive disorders need. Despite the thousands of studies that have been conducted on major depression and the hundreds of randomized trials that have examined the effects of treatments, many patients still do not know how to cope with the daily problems caused by depressive disorders. In this Commentary the need for more research on the perspectives of patients is described. This research should guide treatment studies as well as basic research much more than it currently does. This perpective is especially important to understand and solve the undertreatment of depression, one of the... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4841156 Tue, 17 May 2011 23:00:00 +0100 4841156 Aripiprazole Augmentation in the Treatment of Military-Related PTSD with Major Depression: a retrospective chart review http://www.medworm.com/index.php?rid=4841159&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F86 Background: In this chart review, we attempted to evaluate the benefits of adding aripiprazole in veterans with military-related PTSD and comorbid depression, who had been minimally or partially responsive to their existing medications. Methods: A retrospective chart review of patients who received an open-label, flexible-dose, 12- week course of adjunctive aripiprazole was conducted in 27 military veterans meeting DSM-IV criteria for PTSD and comorbid major depression. Concomitant psychiatric medications continued unchanged, except for other antipsychotics which were discontinued prior to initiating aripiprazole. The primary outcome variable was a change from baseline in the PTSD checklist-military version (PCL-M) and the Beck Depression Inventory (BDI-II). Results: PTSD severity (Total P... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4841159 Mon, 16 May 2011 23:00:00 +0100 4841159 Change in Level of Productivity in the Treatment of Schizophrenia with Olanzapine or Other Antipsychotics http://www.medworm.com/index.php?rid=4841158&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F87 Background: : When treating schizophrenia, improving patients' productivity level is a major goal considering schizophrenia is a leading cause of functional disability. Productivity level has been identified as the most preferred treatment outcome by patients with schizophrenia. However, little has been done to systematically investigate productivity levels in schizophrenia. We set out to better understand the change in productivity level among chronically ill patients with schizophrenia treated with olanzapine compared with other antipsychotic medications. We also assessed the links between productivity level and other clinical outcomes.MethodS: This post hoc analysis used data from 6 randomized, double-blind clinical trials of patients with schizophrenia or schizoaffective disorder, with... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4841158 Mon, 16 May 2011 23:00:00 +0100 4841158 Objective Structured Clinical Examinations (OSCEs), Psychiatry and the Clinical Assessment of Skills and Competencies (CASC). Same evidence, different judgement http://www.medworm.com/index.php?rid=4828662&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F85 Discussion: Van der Vleuten's utility model is used to examine the CASC from the viewpoint of a senior psychiatrist. Reliability may be equivalent to more traditional examinations. Whilst the CASC is likely to have content validity, other forms of validity are untested and authenticity is poor. Educational impact has the potential to change facets of psychiatric professionalism and influence future patient care. There are doubts about acceptability from candidates and more senior psychiatrists. Summary: Whilst OSCEs may be the best choice for medical student examinations, their use in post graduate psychiatric examination in the UK is subject to challenge on the grounds of validity, authenticity and educational impact. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4828662 Sun, 15 May 2011 23:00:00 +0100 4828662 Validity of the 32-item Hypomania Checklist (HCL-32) in a clinical sample with mood disorders in China http://www.medworm.com/index.php?rid=4828663&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F84 Conclusions: This study demonstrated that the simplified Chinese version of HCL-32 was valid for patients with mood disorders. The optimal cut-off of 13 for distinguishing between BP-II and UP was valid and could be used to improve the sensitivity of screening BP-II patients when the HCL-32 is used in psychiatric settings in China. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4828663 Sat, 14 May 2011 23:00:00 +0100 4828663 The Clinical Global Impression Scale and the influence of patient or staff perspective on outcome http://www.medworm.com/index.php?rid=4828664&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F83 Background: Since its first publication, the Clinical Global Impression Scale (CGI) has become one of the most widely used assessment instruments in psychiatry. Although some conflicting data has been presented, studies investigating the CGI's validity have only rarely been conducted so far. It is unclear whether the improvement index CGI-I or a difference score of the severity index CGI-Sdif is more valid in depicting clinical change. The current study examined the validity of these two measures and investigated whether therapists' CGI ratings correspond to the view the patients themselves have on their condition. Methods: Thirty-one inpatients of a German psychotherapeutic hospital suffering from a major depressive disorder (age M=45.3, SD=17.2; 58.1% women) participated. Patients filled... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4828664 Fri, 13 May 2011 23:00:00 +0100 4828664 Group cognitive behavioural therapy for women with depression: pilot and feasibility study for a randomised controlled trial using mixed methods http://www.medworm.com/index.php?rid=4820627&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F82 Conclusions: This study showed that a randomised controlled trial of group CBT for women with depression is feasible and the intervention is acceptable, and may possibly prove to be effective in a larger trial. The cost effectiveness of group CBT for depression should be explored further in a full trial.Trial registration: NCT00663078 (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4820627 Thu, 12 May 2011 23:00:00 +0100 4820627 Using internet enabled mobile devices and social networking technologies to promote exercise as an intervention for young first episode psychosis patients http://www.medworm.com/index.php?rid=4820628&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F80 This study is a qualitative pilot study being conducted at Orygen Youth Health Research Centre in Melbourne, Australia. Participants are young people aged 15-24 who are receiving clinical care at a specialist first episode psychosis treatment centre. Participants will also comprise young people from the general population. The exercise intervention is a 9-week running program, designed to gradually build a person's level of fitness to be able to run 5 kilometres (3 miles) towards the end of the program. The program will be delivered via an internet enabled mobile device. Participants will be asked to post messages about their running experiences on the social networking website, and will also be asked to attend three face-to-face interviews.DiscussionThis paper describes the development of... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4820628 Wed, 11 May 2011 23:00:00 +0100 4820628 Onset of efficacy and tolerability following the initiation dosing of long-acting paliperidone palmitate: post-hoc analyses of a randomized, double-blind clinical trial http://www.medworm.com/index.php?rid=4820629&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F79 Background: Paliperidone palmitate is a long-acting injectable atypical antipsychotic for the acute and maintenance treatment of adults with schizophrenia. The recommended initiation dosing regimen is 234 mg on Day 1 and 156 mg on Day 8 via intramuscular (deltoid) injection; followed by 39 to 234 mg once-monthly thereafter (deltoid or gluteal). These post-hoc analyses addressed two commonly encountered clinical issues regarding the initiation dosing: the time to onset of efficacy and the associated tolerability. Methods: In a 13-week double-blind trial, 652 subjects with schizophrenia were randomized to paliperidone palmitate 39, 156, or 234 mg (corresponding to 25, 100, or 150 mg equivalents of paliperidone, respectively) or placebo (NCT#00590577). Subjects randomized to paliperidone palm... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4820629 Mon, 09 May 2011 23:00:00 +0100 4820629 Alertness and visuospatial attention in clinical depression http://www.medworm.com/index.php?rid=4802134&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F78 Conclusions: Decreased alertness may lead to lower left hemifield visuospatial attention; this mechanism may be responsible for a spatial bias to the right side in depression, even though treatment of depression and anxiety may reduce this cognitive deficit. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4802134 Sun, 08 May 2011 23:00:00 +0100 4802134 Perceived discrimination is associated with severity of positive and depression/anxiety symptoms in immigrants with psychosis: A cross-sectional study http://www.medworm.com/index.php?rid=4794703&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F77 Conclusions: Among immigrants with psychotic disorders, visible minority status was associated with perceived discrimination and with more severe positive and depression/anxiety symptoms. These results suggest that context-specific stressful environmental factors influence specific symptom patterns and severity. This has important implications for preventive strategies and treatment of this vulnerable patient group. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4794703 Thu, 05 May 2011 23:00:00 +0100 4794703 Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder http://www.medworm.com/index.php?rid=4788931&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F76 Conclusion: Functional MRI may help identify intermediate phenotypes and dimensions of PTSD that clarify the functional link between genes and disease phenotype following exposure to trauma. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4788931 Wed, 04 May 2011 23:00:00 +0100 4788931 Validation of brief screening tools for depressive and alcohol use disorders among TB and HIV patients in primary care in Zambia http://www.medworm.com/index.php?rid=4788933&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F75 Conclusions: The CES-D and AUDIT showed high discriminatory ability in measuring MINI-defined current MDD and AUD respectively. They are suitable mental health screening tools for use among TB and ART patients in primary care in Zambia. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4788933 Tue, 03 May 2011 23:00:00 +0100 4788933 A comparative study on long-term evoked auditory and visual potential responses between Schizophrenic patients and normal subjects http://www.medworm.com/index.php?rid=4788932&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F74 Conclusions This study shows the methodology of application of auditory and visual oddball paradigm identifies task-relevant sources of activity and allows separation of regions that have different response properties. Our study indicates that there may be slowness of automatic cognitive processing and controlled cognitive processing of visual ERPs compared to auditory ERPs in schizophrenic patients. The activation changes of visual evoked potentials are more regionally specific than auditory evoked potentials. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4788932 Tue, 03 May 2011 23:00:00 +0100 4788932 The personal and national costs of mental health conditions: impacts on income, taxes, government support payments due to lost labour force participation http://www.medworm.com/index.php?rid=4762679&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F72 Conclusions: The costs of mental health conditions to the individuals and the state are considerable. While individuals has to bear the economic costs of lost income in addition to the burden of the conditions itself, the impact on the state is loss of productivity from reduced workforce participation, lost income taxation revenue, and increased government support payments - in addition to direct health care costs. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4762679 Wed, 27 Apr 2011 23:00:00 +0100 4762679 Profile of subjective quality of life and its correlates in a nation-wide sample of high school students in an Arab setting using the WHOQOL-Bref http://www.medworm.com/index.php?rid=4753535&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F71 Conclusion: Poorer QOL seemed to reflect a circumstance of social disadvantage and poor psychosocial well-being in which girls fared worse than boys. The findings indicate that programs that address parental harmony and school programs that promote study-friendly atmospheres could help to improve psychosocial well-being. The application of QOL as a school population health measure may facilitate risk assessment and the tracking of health status. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4753535 Sun, 24 Apr 2011 23:00:00 +0100 4753535 Factors affecting staff morale on inpatient mental health wards in England: a qualitative investigation http://www.medworm.com/index.php?rid=4733778&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F68 Conclusions: Increasing employee voice, designing jobs so as to maximise autonomy within clear and well-structured operational protocols, promoting greater staff-patient contact and improving responses to violence may contribute more to inpatient staff morale than formal support mechanisms. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4733778 Wed, 20 Apr 2011 23:00:00 +0100 4733778 Functional impairment related to painful physical symptoms in patients with generalized anxiety disorder with or without comorbid major depressive disorder: post hoc analysis of a cross-sectional study http://www.medworm.com/index.php?rid=4733777&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F69 The objective of the present study is to assess functional impairment related to the presence of PPS in patients with GAD. Methods: This is a post hoc analysis of a cross-sectional study. Functioning, in the presence (overall pain score >30; Visual Analog Scale) or absence of PPS, was assessed using the Sheehan Disability Scale (SDS) in three groups of patients; 1) GAD and comorbid MDD (GAD+MDD+), 2) GAD without comorbid MDD (GAD+MDD-), 3) controls (GAD-MDD-). ANCOVA models were used. Results: Of those patients with GAD+MDD+ (n=559), 436 (78.0%) had PPS, compared with GAD+MDD- (249 of 422, 59%) and controls (95 of 336, 28.3%). Functioning worsened in both GAD groups in presence of PPS (SDS least squares mean total score: 16.1 vs. 9.8, p (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4733777 Wed, 20 Apr 2011 23:00:00 +0100 4733777 Relation between therapeutic response and side effects induced by methylphenidate as observed by parents and teachers of children with ADHD http://www.medworm.com/index.php?rid=4733776&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F70 Conclusion: The greater "mood/anxiety" sides effects on methylphenidate and placebo the less the parents observe improvement of their children while treated with methylphenidate. This suggests that the correlations between "mood/anxiety" side effects and poor response to treatment may be driven by observer effects rather than biological commonalities between therapeutic and side effects of methylphenidate. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4733776 Wed, 20 Apr 2011 23:00:00 +0100 4733776 The effect of ethnicity on prescribing practice and treatment outcome in inpatients suffering from schizophrenia in Greece http://www.medworm.com/index.php?rid=4733780&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F66 Conclusions: Our study found limited evidence for ethnic bias. The stronger indication for racial bias was found in benzodiazepine prescribing. We discuss alternative explanations and give arguments calling for future research that will focus on disorders other than schizophrenia and studying non-inpatient populations. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4733780 Tue, 19 Apr 2011 23:00:00 +0100 4733780 Typology of adults diagnosed with mental disorders based on socio-demographics and clinical and service use characteristics http://www.medworm.com/index.php?rid=4733779&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F67 Conclusion: The study found considerable heterogeneity among socio-demographic characteristics, number of disorders, and number of health-care services used by individuals with mental or dependence disorders. Cluster analysis revealed important differences in service use with regard to gender and age. It reinforces the relevance of developing targeted programs for subgroups of individuals with mental and/or dependence disorders. Strategies aimed at changing low service users' attitude (youths and males) or instituting specialised programs for that particular clientele should be promoted. Finally, as concomitant disorders are frequent among individuals with mental disorder, psychological services and/or addiction programs must be prioritised as components of integrated services when plannin... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4733779 Tue, 19 Apr 2011 23:00:00 +0100 4733779 Clinical symptoms and performance on the continuous performance test in children with attention deficit hyperactivity disorder between subtypes: a natural follow-up study for 6 months http://www.medworm.com/index.php?rid=4733781&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F65 Conclusions: We found that ADHD symptoms, which included impulsive performances in CPT and clinical inattention and hyperactivity dimensions, had improved significantly over 6 months under pragmatic treatments. The non-aggressive ADHD patients might have a higher potential for improving in CPT performance than aggressive ones. However, it warrant further investigation whether the different classifications of ADHD patients could be valid for predicting the improvements in ADHD patients' clinical symptoms and neurocognitive performance. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4733781 Mon, 18 Apr 2011 23:00:00 +0100 4733781 Dual diagnosis clients' treatment satisfaction - a systematic review http://www.medworm.com/index.php?rid=4733782&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F64 Conclusions: High satisfaction levels with current treatment provision, especially among those in integrated treatment, should enhance therapeutic optimism among practitioners dealing with DD clients. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4733782 Sun, 17 Apr 2011 23:00:00 +0100 4733782 Systematic review of safety and tolerability of a complex micronutrient formula used in mental health http://www.medworm.com/index.php?rid=4723617&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F62 Conclusions: This compilation of safety and tolerability data is reassuring with respect to the broad spectrum approach that employs complex nutrient formulae as a primary treatment. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4723617 Sun, 17 Apr 2011 23:00:00 +0100 4723617 Psychological Quality of Life and its association with Academic Employability Skills among newly-registered students from three European Faculties http://www.medworm.com/index.php?rid=4723616&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F63 Background: In accord with new European university reforms initiated by the Bologna Process, our objectives were to assess psychological quality of life (QoL) and to analyse its associations with academic employability skills (AES) among students from the Faculty of Language, Literature, Humanities, Arts and Education, Walferdange Luxembourg (F1, mostly vocational/applied courses); the Faculty of Social and Human Sciences, Liege, Belgium (F2, mainly general courses); and the Faculty of Social Work, Iasi, Romania (F3, mainly vocational/professional courses).MethodStudents who redoubled or who had studied at other universities were excluded. 355 newly-registered first-year students (145 from F1, 125 from F2, and 85 from F3) were invited to complete an online questionnaire (in French, German,... BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4723616 Sun, 17 Apr 2011 23:00:00 +0100 4723616 Comparison of the CES-D and PHQ-9 depression scales in people with type 2 diabetes in Tehran, Iran http://www.medworm.com/index.php?rid=4723618&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F61 Conclusions: It could be concluded that the PHQ-9 and CES-D perform well as screening instruments, but in diagnosing major depressive disorder, a formal diagnostic process following the PHQ-9 and also the CES-D remains essential. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4723618 Fri, 15 Apr 2011 23:00:00 +0100 4723618 Familial liability, obstetric complications and childhood development abnormalities in early onset schizophrenia: a case control study http://www.medworm.com/index.php?rid=4714600&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F60 Conclusions: This study confirms the significant role of familial liability but not of obstetric complications in the pathogenesis of VEOS/EOS; the association between childhood developmental abnormalities and EOS/VEOS supports the neurodevelopmental model of disease. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4714600 Wed, 13 Apr 2011 23:00:00 +0100 4714600 ESPECTRA: Searching the Bipolar Spectrum in Eating Disorder patients http://www.medworm.com/index.php?rid=4709065&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F59 DiscussionThe classificatory systems in psychiatry are based on categorical models that have been criticized for simplifying the diagnosis and leading to an increase in comorbidities. Some dimensional approaches have been proposed aimed at improving the validity and reliability of psychiatric disorder assessments, especially in conditions with high rates of comorbidity such as BD and Eating Disorder (ED). The Bipolar Spectrum (BS) remains under-recognized in clinical practice and its definition is not well established in current diagnostic guidelines. Broader evaluation of psychiatric disorders combining categorical and dimensional views could contribute to a more realistic understanding of comorbidities and help toward establishing a prognosis. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4709065 Wed, 13 Apr 2011 23:00:00 +0100 4709065 Pre-post changes in psychosocial functioning among relatives of patients with depressive disorders after Brief Multifamily Psychoeducation: A pilot study http://www.medworm.com/index.php?rid=4696524&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F56 Conclusions: This study suggests that brief multifamily psychoeducation is a useful intervention to reduce the psychosocial burden of the relatives of patients with depressive disorder. Further evaluation of family psychoeducation for relatives of patients with depressive disorder is warranted. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4696524 Sun, 10 Apr 2011 23:00:00 +0100 4696524 The impact of ADHD and conduct disorder in childhood on adult delinquency: A 30 years follow-up study using official crime records. http://www.medworm.com/index.php?rid=4696523&cid=s_34047_172_f&fid=34047&url=http%3A%2F%2Fwww.biomedcentral.com%2F1471-244X%2F11%2F57 Conclusions Conduct disorder in childhood was highly associated with later delinquency both alone or in combination with hyperactivity, but less associated when combined with an emotional disorder. ADHD in childhood was no more associated with later delinquency than the rest of the disorders in the study population. Our finding strengthens the assumption that there is no direct association between ADHD and criminality. (Source: BMC Psychiatry - Latest articles) BMC Psychiatry - Latest articles journals http://www.medworm.com/rss/comments.php?id=4696523 Sun, 10 Apr 2011 23:00:00 +0100 4696523