MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'British Journal of Dermatology' source. Wed, 08 Feb 2012 13:12:28 +0100 http://www.medworm.com/index.php?rid=5667248&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10877.x Conclusions:  The observed association suggests that the AR/EDA2R locus confers susceptibility to early onset FHPL. Our results do no implicate the 20p11 locus in the aetiology of FPHL. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667248 Mon, 06 Feb 2012 05:00:00 +0100 5667248 http://www.medworm.com/index.php?rid=5667247&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10878.x Conclusion:  Two sessions of DMSO supportive topical ALA‐PDT and curettage can provide long‐term effective treatment results with favourable cosmetic outcome in primary, small BCC. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667247 Mon, 06 Feb 2012 05:00:00 +0100 5667247 http://www.medworm.com/index.php?rid=5667246&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10879.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667246 Mon, 06 Feb 2012 05:00:00 +0100 5667246 http://www.medworm.com/index.php?rid=5667245&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10880.x Conclusions:  The majority of dermatologists and rheumatologists are similar in their initial use of MTX in PsO but differ in how they proceed with therapy. The use of SC MTX and MTX combination therapy in PsO requires further investigation. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667245 Mon, 06 Feb 2012 05:00:00 +0100 5667245 http://www.medworm.com/index.php?rid=5667244&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10881.x Conclusions:  This is the first study to demonstrate the prospective accumulation of MTXPG1‐5 in patients with psoriasis. The detection of MTXPGs early in therapy and the establishment of a steady state with continuous treatment may offer measuring MTXPG as a test to monitor patient compliance with therapy. Larger studies are required to determine the role of MTXPG as a potential biomarker of clinical response. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667244 Mon, 06 Feb 2012 05:00:00 +0100 5667244 http://www.medworm.com/index.php?rid=5667243&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10882.x Conclusion:  Our case series demonstrates the efficacy and favourable side effect profile of MMF in the treatment of severe ulcerative lichen planus. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667243 Mon, 06 Feb 2012 05:00:00 +0100 5667243 http://www.medworm.com/index.php?rid=5667242&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10883.x Conclusions:  We characterised inflammatory and atherogenic profiles of Spanish psoriasis patients compared to matched controls. After NBUVB therapy we demonstrated improvement in psoriasis and some systemic inflammation markers, which were not mediated by enhancement of vitamin D synthesis. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667242 Mon, 06 Feb 2012 05:00:00 +0100 5667242 http://www.medworm.com/index.php?rid=5667241&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10884.x Discussions:  We suggested that anti‐LAMP‐2 antibody could play some role in the pathogenesis of adult HSP, with the exception of MPO‐ANCA and PR3‐ANCA. We proposed that measuring serum anti‐LAMP‐2 antibody could be a feasible method of differential diagnosis between HSP and MPA. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5667241 Wed, 01 Feb 2012 05:00:00 +0100 5667241 http://www.medworm.com/index.php?rid=5647909&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10868.x Conclusions:  PP, LP, PR and dermatitis show specific dermoscopic patterns that may aid their clinical diagnosis. Certain combinations of dermoscopic features can reliably predict the diagnosis of PP. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647909 Wed, 01 Feb 2012 05:00:00 +0100 5647909 http://www.medworm.com/index.php?rid=5647908&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10869.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647908 Wed, 01 Feb 2012 05:00:00 +0100 5647908 http://www.medworm.com/index.php?rid=5647907&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10870.x AbstractThis review investigates the effectiveness of ablative and non‐ablative Fractional Photothermolysis (FP) lasers for treating facial acne scars. 26 studies (13=ablative FP; 13=non‐ablative FP) published between year‐2003 to January 2011 were reviewed. Quantitative and qualitative data from each article were examined and analysed. 4 studies were split‐face randomised controlled studies (RCTs). Whilst the data analysed where all clinically relevant and significant, there were some methodological differences between the studies. Outcomes included subjective and objective assessment of scar appearance, pre‐ and postoperative treatment, side effects and pain scores. A small number of studies used 3D Optical Profiling Imaging and histology for objective assessment. Even allowing... British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647907 Wed, 01 Feb 2012 05:00:00 +0100 5647907 http://www.medworm.com/index.php?rid=5647906&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10871.x AbstractMutation of the genes encoding components of the TNFα‐like (tumour necrosis factor α) pathway involved in signal transduction between the ectoderm and the mesenchyme during embryonic development causes hypohidrotic ectodermal dysplasia (HED), resulting from the abnormal differentiation of tooth buds, hair follicles and eccrine sweat glands. Two phenotypically indistinguishable forms of HED, X‐linked recessive and autosomal (dominant or recessive), have been discerned in mice and humans.1 The X‐linked form (OMIM #305100) is caused by mutations in the ED1 gene, which encodes two principal ectodysplasins. EDA‐A1 is recognized by receptor EDA1R (ectodysplasin A1 receptor), causing the recruitment of an adaptor, EDARADD (EDA1R‐associated death domain), which interacts with T... British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647906 Wed, 01 Feb 2012 05:00:00 +0100 5647906 http://www.medworm.com/index.php?rid=5647913&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10864.x AbstractThe genetic predisposition to melanoma is quite heterogeneous. The major locus for melanoma predisposition is the cell cycle regulatory CDKN2A gene on chromosome 9p21 though alterations in it have been detected in only 20 40% of melanoma prone families. However, with regard to the frequency of melanoma‐prone families linked to 9p21, the frequency of germline coding mutations of the CDKN2A gene is lower than expected. We set out to investigate whether the rare IVS1+37 G/C intronic mutation of the CDKN2A gene recently identified in a Hungarian melanoma prone family, influences mRNA splicing regulation. To this end, CDKN2A minigenes containing the wild type and the mutant intronic sequence were created and transfected into HeLa cells with the aim of study of the mRNA transcripts. Th... British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647913 Tue, 31 Jan 2012 05:00:00 +0100 5647913 http://www.medworm.com/index.php?rid=5647912&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10865.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647912 Tue, 31 Jan 2012 05:00:00 +0100 5647912 http://www.medworm.com/index.php?rid=5647911&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10866.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647911 Tue, 31 Jan 2012 05:00:00 +0100 5647911 http://www.medworm.com/index.php?rid=5647910&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10867.x Conclusions:  Differences in the methylation status of these TRGs in the SLN(+) pediatric and adult melanoma patients may account for why SLN(+) pediatric patients have different clinical outcomes. SLN biopsy should continue to be performed; within SLN(+) pediatric melanoma patients, hypermethylation of TRGs can be used to identify a subpopulation at highest risk for poor outcomes who warrant vigilant clinical follow‐up. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647910 Tue, 31 Jan 2012 05:00:00 +0100 5647910 http://www.medworm.com/index.php?rid=5638531&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10857.x Conclusions:  The EMCPPTS has provided current information on the relative frequency of PACD to common photoallergens. Such data will be of value when deciding on which agents to include in future European “baseline” photopatch test series. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638531 Sun, 29 Jan 2012 17:16:17 +0100 5638531 http://www.medworm.com/index.php?rid=5638545&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10844.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638545 Fri, 27 Jan 2012 05:00:00 +0100 5638545 http://www.medworm.com/index.php?rid=5638544&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10843.x Conclusion NT may play a role in Ps pathogenesis and its worsening with stress, at least through activation of skin mast cells. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638544 Fri, 27 Jan 2012 05:00:00 +0100 5638544 http://www.medworm.com/index.php?rid=5638543&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10845.x Conclusions:  In the absence of markedly better efficacy against the various cycline indications, the minocycline benefit/risk ratio was clearly lower than that of doxycycline, and possibly those of lymecycline and metacycline. In light of these findings, minocycline should no longer be considered first‐line therapy for inflammatory skin disorders, especially acne. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638543 Fri, 27 Jan 2012 05:00:00 +0100 5638543 http://www.medworm.com/index.php?rid=5638542&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10846.x Conclusions:  While their diameter minimally changed over time, most SGM became more disorganized, revealed loss of network in favor of structureless areas, and developed new colors. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638542 Fri, 27 Jan 2012 05:00:00 +0100 5638542 http://www.medworm.com/index.php?rid=5638541&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10848.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638541 Fri, 27 Jan 2012 05:00:00 +0100 5638541 http://www.medworm.com/index.php?rid=5638540&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10847.x Conclusion:  As hBD2 played multifaceted roles during the wound healing process, the inadequate expression of hBD2 during the diabetic conditions contributes to the impaired wound healing. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638540 Fri, 27 Jan 2012 05:00:00 +0100 5638540 http://www.medworm.com/index.php?rid=5638539&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10850.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638539 Fri, 27 Jan 2012 05:00:00 +0100 5638539 http://www.medworm.com/index.php?rid=5638538&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10849.x Conclusions:  In contrast to other fMRI studies we observed multifocal negative signal. An improved understanding of both activated and deactivated brain regions during the itch response may in the long‐term facilitate development of more effective management strategies. [246/250] (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638538 Fri, 27 Jan 2012 05:00:00 +0100 5638538 http://www.medworm.com/index.php?rid=5638537&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10851.x We describe a diagnostically challenging case of EED with marked oral ulceration, a feature not previously described in the literature to our knowledge. Treatment with dapsone resulted in a dramatic improvement in both cutaneous and oral manifestations of the disease in this case. The mechanism of oral ulceration may be due to an attenuated response by neutrophils to a bacterial peptide resulting in a diminished host defence against commensal oral pathogens. This has previously been described in the development of oral ulcers and periodontal disease in patients with neutrophil dysfunction and neutropenia. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638537 Fri, 27 Jan 2012 05:00:00 +0100 5638537 http://www.medworm.com/index.php?rid=5638536&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10852.x Discussion:  We suspect that individuals with self‐reported atopic dermatitis from this study mainly suffered from mild disease. However, clinicians should be aware of increased levels of contact sensitization in individuals with atopic dermatitis. Patch testing should therefore be considered at an early point in individuals with a history of atopic dermatitis and active disease. The fundamental relationship between atopic disease and environmental chemical exposure may be of a more complex and intimate nature than previously supposed. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638536 Fri, 27 Jan 2012 05:00:00 +0100 5638536 http://www.medworm.com/index.php?rid=5638535&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10854.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638535 Fri, 27 Jan 2012 05:00:00 +0100 5638535 http://www.medworm.com/index.php?rid=5638534&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10853.x Conclusion:  P‐cadherin expression in MCCs predicts prolonged recurrence‐free survival and may therefore indicate favourable prognosis. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638534 Fri, 27 Jan 2012 05:00:00 +0100 5638534 http://www.medworm.com/index.php?rid=5638533&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10855.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638533 Fri, 27 Jan 2012 05:00:00 +0100 5638533 http://www.medworm.com/index.php?rid=5638532&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10856.x Conclusions:  These results suggest that androgens deregulate DPC‐secreted factors involved in normal HF stem cell differentiation via the inhibition of the canonical Wnt signalling pathway. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5638532 Fri, 27 Jan 2012 05:00:00 +0100 5638532 http://www.medworm.com/index.php?rid=5620159&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10804.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620159 Mon, 23 Jan 2012 17:26:53 +0100 5620159 http://www.medworm.com/index.php?rid=5620158&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10687.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620158 Mon, 23 Jan 2012 17:26:52 +0100 5620158 http://www.medworm.com/index.php?rid=5620157&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10697.x Conclusions  Exposure to a UVB dose of 1 SED every second week to ∼88% body area is sufficient for maintaining summer 25(OH)D levels during the winter. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620157 Mon, 23 Jan 2012 17:26:26 +0100 5620157 http://www.medworm.com/index.php?rid=5620156&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10667.x Conclusions  Providers are encouraged to address vitamin D insufficiency concerns in all dark‐skinned individuals. Future studies should stratify subjects by skin colour in determining differences between subjects with CLE and normal controls. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620156 Mon, 23 Jan 2012 17:26:12 +0100 5620156 http://www.medworm.com/index.php?rid=5620155&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10592.x Conclusion  Malnutrition was observed in 50% of the children with generalized RDEB. Protein and energy needs are particularly high. GTF is well tolerated and helps with catch‐up growth and puberty. It must be considered before malnutrition onset, and, if necessary, before puberty. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620155 Mon, 23 Jan 2012 17:26:09 +0100 5620155 http://www.medworm.com/index.php?rid=5620153&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10698.x Conclusions  Adalimumab treatment inhibits important cytokines and inflammatory cell numbers in lesional HS skin, especially levels of IL‐1β and numbers of inflammatory CD11c+ dendritic cells. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620153 Mon, 23 Jan 2012 17:25:57 +0100 5620153 http://www.medworm.com/index.php?rid=5620151&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10767.x SummaryThe Centre of Evidence Based Dermatology, University of Nottingham, U.K. holds an annual Evidence Based Update (EBU) Meeting focused on important dermatological topics, which have in the past included eczema, urticaria, blistering disorders, skin infections, skin cancer and hair disorders. These one‐day meetings aim to summarize the most recent evidence in the form of systematic reviews and recently completed clinical trials. This year, the 9th EBU meeting took place in Loughborough, U.K. on 12 May 2011 and was devoted to psoriasis. The latest updates on topical treatments, nail psoriasis, genetics and clinical implications, rational use of biologics, new and unpublished studies on combination of phototherapy and biologics for psoriasis, and on treatments of palmoplantar pustular ... British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620151 Mon, 23 Jan 2012 17:25:45 +0100 5620151 http://www.medworm.com/index.php?rid=5620150&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10801.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620150 Mon, 23 Jan 2012 17:25:40 +0100 5620150 http://www.medworm.com/index.php?rid=5620149&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10802.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620149 Mon, 23 Jan 2012 17:25:38 +0100 5620149 http://www.medworm.com/index.php?rid=5620148&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10739.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620148 Mon, 23 Jan 2012 17:25:36 +0100 5620148 http://www.medworm.com/index.php?rid=5620146&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10803.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620146 Mon, 23 Jan 2012 17:25:34 +0100 5620146 http://www.medworm.com/index.php?rid=5620137&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10829.x Conclusions:  E‐health during follow up of patients with AD is, after initial diagnosis and treatment during face to face contact, just as effective as usual face‐to‐face care with regard to quality of life and severity of complaints. However, when costs are considered, e‐health is likely to result in substantial cost savings. Therefore, e‐health is a valuable service for patients with AD. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5620137 Mon, 23 Jan 2012 17:21:54 +0100 5620137 http://www.medworm.com/index.php?rid=5608926&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10830.x Conclusion:  Non‐melanoma skin cancer is an increasing problem for health care services worldwide. This review highlights a requirement for prevention studies in this area and the issues surrounding incomplete NMSC registration. Registration standards of NMSC should be improved to the level of other invasive disease. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608926 Tue, 17 Jan 2012 05:00:00 +0100 5608926 http://www.medworm.com/index.php?rid=5608925&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10831.x Conclusion:  This is the first time that GSTP1 rs1695 polymorphism is reported to be associated to melanoma. In addition, this study is one of the largest GSTs polymorphisms studies undertaken in the Spanish population and the first time that copy number variants have been scrutinized in relation to MM. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608925 Tue, 17 Jan 2012 05:00:00 +0100 5608925 http://www.medworm.com/index.php?rid=5608924&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10832.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608924 Tue, 17 Jan 2012 05:00:00 +0100 5608924 http://www.medworm.com/index.php?rid=5608923&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10833.x Conclusion:  Daylight‐mediated PDT of moderate to thick AKs was less effective than daylight‐mediated PDT of thin AKs especially in some centres. However, nearly all thicker lesions (grades II and III) were reduced to a lower lesion grade at 3 months after a single treatment of daylight‐mediated PDT. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608923 Tue, 17 Jan 2012 05:00:00 +0100 5608923 http://www.medworm.com/index.php?rid=5581891&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10820.x Conclusions:  Recombinant BP230‐C3 is a suitable target antigen for the detection of serum autoantibodies against BP230. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581891 Fri, 13 Jan 2012 05:00:00 +0100 5581891 http://www.medworm.com/index.php?rid=5581890&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10821.x Conclusions:  Although TCSs are considered to be first line treatment, we identified no RCTs that compared TCSs with placebo in patients with symptomatic OLP. From the 28 trials included in this systematic review, the wide range of interventions compared means there is insufficient evidence to support the effectiveness of any specific treatment as being superior. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581890 Fri, 13 Jan 2012 05:00:00 +0100 5581890 http://www.medworm.com/index.php?rid=5581889&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10822.x Conclusions:  Measurement of CTT allows for individualized risk management and therapy to patients with cold urticaria. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581889 Fri, 13 Jan 2012 05:00:00 +0100 5581889 http://www.medworm.com/index.php?rid=5581888&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10825.x Conclusions:  Patients with SCLE and DLE have an IFN signature, as seen in SLE. The level of gene expression correlates with cutaneous disease activity. These findings support a shared pathogenesis between SLE and some subtypes of CLE. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581888 Fri, 13 Jan 2012 05:00:00 +0100 5581888 http://www.medworm.com/index.php?rid=5581887&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10823.x Conclusions:  Reduction of Langerhans cells during clinical treatment of BCC might potentially impact negatively on anti‐tumour responses through reduced activation of tumour‐specific effector cells. Investigation of modified PDT protocols with the aim to minimise immunosuppressive effects whilst maintaining anti‐tumour efficacy is warranted. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581887 Fri, 13 Jan 2012 05:00:00 +0100 5581887 http://www.medworm.com/index.php?rid=5581886&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10826.x Conclusions:  There are topographical differences in itch intensity, the effectiveness of scratching in relieving itch and the associated pleasurability. Experimental itch induced by cowhage was more intensely perceived at the ankle, while scratching attenuated itch most effectively on the back. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581886 Fri, 13 Jan 2012 05:00:00 +0100 5581886 http://www.medworm.com/index.php?rid=5581885&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10827.x Conclusions:  These results indicate that antigenetic diversity of anti‐Dsg1 antibodies in these cases may cause the unique oral mucosal and cutaneous lesions, although further studies are required to elucidate real pathomechanisms. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581885 Fri, 13 Jan 2012 05:00:00 +0100 5581885 http://www.medworm.com/index.php?rid=5581897&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10814.x Conclusions:  Psoriasis and atopic dermatitis thus associate with quantitative and qualitative changes of peripheral NK cells, mostly shared by both diseases, supporting a common process implicating these innate effectors in skin inflammation. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581897 Wed, 11 Jan 2012 05:00:00 +0100 5581897 http://www.medworm.com/index.php?rid=5581896&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10815.x Conclusions:  Our results indicate the clear superiority of topical antifungals over placebo but that there is no consistent difference among classes. Mixed treatment comparisons are necessary to rank antifungals, since direct comparisons among many of them are lacking. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581896 Wed, 11 Jan 2012 05:00:00 +0100 5581896 http://www.medworm.com/index.php?rid=5581895&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10816.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581895 Wed, 11 Jan 2012 05:00:00 +0100 5581895 http://www.medworm.com/index.php?rid=5581894&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10817.x We report on a 50‐year‐old woman who presented disfiguring facial edema 1 month after the initiation of omalizumab treatment for severe persistent allergic asthma. She had received multiple cosmetic filler injections, including hyaluronic acid and calcium hydroxylapatite, for 4 years without any previous side effects. A biopsy of a lip nodule revealed a foreign‐body granulomatous reaction. Treatment was with high‐dose prednisone and doxycycline, with clinical improvement.As was previously reported with interferon, foreign‐body granulomatous reaction may occur with omaluzimab treatment after dermal filler injections. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581894 Wed, 11 Jan 2012 05:00:00 +0100 5581894 http://www.medworm.com/index.php?rid=5581893&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10819.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581893 Wed, 11 Jan 2012 05:00:00 +0100 5581893 http://www.medworm.com/index.php?rid=5581892&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10818.x Conclusions:  Our data seem to indicate that CTACK/CCL27 levels in skin and sera after therapy might be correlated with risk of recurrence. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581892 Wed, 11 Jan 2012 05:00:00 +0100 5581892 http://www.medworm.com/index.php?rid=5581905&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10805.x Conclusions:  Skin cancer prevention campaigns should target the encouragement of sun protection for children also in outdoor activities of daily living, not only during a summer holiday on the beach. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581905 Mon, 09 Jan 2012 05:00:00 +0100 5581905 http://www.medworm.com/index.php?rid=5581904&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10806.x Conclusion:  Skindex has better sensitivity to clinical severity with minimal floor effect, and cover the main domains explored by the other 3 QoL instruments in patients with mild to severe psoriasis. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581904 Mon, 09 Jan 2012 05:00:00 +0100 5581904 http://www.medworm.com/index.php?rid=5581903&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10807.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581903 Mon, 09 Jan 2012 05:00:00 +0100 5581903 http://www.medworm.com/index.php?rid=5581902&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10808.x Conclusions:  Because the clinical outcome and prognosis is different it is important to distinguish between males with CHH syndrome that represents a mosaic phenotype, and those with MEND syndrome that is a nonmosaic trait. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581902 Mon, 09 Jan 2012 05:00:00 +0100 5581902 http://www.medworm.com/index.php?rid=5581901&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10809.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581901 Mon, 09 Jan 2012 05:00:00 +0100 5581901 http://www.medworm.com/index.php?rid=5581900&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10810.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581900 Mon, 09 Jan 2012 05:00:00 +0100 5581900 http://www.medworm.com/index.php?rid=5581899&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10811.x Conclusions:  This study demonstrates the presence of the cutaneous features of PXE in a genetically distinct disease, generalized arterial calcification of infancy, and thus expands the spectrum of PXE‐related disorders. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581899 Mon, 09 Jan 2012 05:00:00 +0100 5581899 http://www.medworm.com/index.php?rid=5581898&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10812.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581898 Mon, 09 Jan 2012 05:00:00 +0100 5581898 http://www.medworm.com/index.php?rid=5608922&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10834.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608922 Sun, 01 Jan 2012 05:00:00 +0100 5608922 http://www.medworm.com/index.php?rid=5581884&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2012.10828.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581884 Sun, 01 Jan 2012 05:00:00 +0100 5581884 http://www.medworm.com/index.php?rid=5552367&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10800.x In this report, we describe two Pakistani families with an autosomal‐recessive inherited nail dysplasia. We mapped this genodermatosis to chromosome 8q22.3, and identified a homozygous nonsense mutation c.1750G>T (p.E584X) in the frizzled 6 (FZD6) gene in all affecteds. Expression analyses in nail sections from healthy individuals revealed strong expression of FZD6 in the ventral nail matrix and a less pronounced expression of FZD6 in the nail bed. FZD6 belongs to a family of proteins that serve as receptors in Wnt signalling pathways, and has been shown to act as a negative regulator of the canonical Wnt/β‐catenin signalling cascade and a positive regulator of the non‐canonical Wnt or planar cell polarity (PCP) pathway. The present results therefore suggest that FZD6 plays a piv... British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552367 Sat, 31 Dec 2011 05:48:25 +0100 5552367 http://www.medworm.com/index.php?rid=5544635&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10762.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544635 Wed, 28 Dec 2011 09:01:03 +0100 5544635 http://www.medworm.com/index.php?rid=5544634&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10770.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544634 Wed, 28 Dec 2011 09:01:02 +0100 5544634 http://www.medworm.com/index.php?rid=5544633&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10768.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544633 Wed, 28 Dec 2011 09:01:00 +0100 5544633 http://www.medworm.com/index.php?rid=5544632&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10668.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544632 Wed, 28 Dec 2011 09:00:59 +0100 5544632 http://www.medworm.com/index.php?rid=5544631&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10520.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544631 Wed, 28 Dec 2011 09:00:55 +0100 5544631 http://www.medworm.com/index.php?rid=5544630&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10521.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544630 Wed, 28 Dec 2011 09:00:48 +0100 5544630 http://www.medworm.com/index.php?rid=5544629&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10512.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544629 Wed, 28 Dec 2011 09:00:43 +0100 5544629 http://www.medworm.com/index.php?rid=5544628&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10539.x Conclusions  Our results provide further evidence that oxidative stress and impairment of the antioxidant system in the plasma of patients may play a role in pathogenesis and progression of psoriasis and related complications. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544628 Wed, 28 Dec 2011 09:00:36 +0100 5544628 http://www.medworm.com/index.php?rid=5544627&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10540.x Conclusions  Good to excellent repigmentation of leucotrichia can be achieved with noncultured cellular grafting, obviating the need for hair transplantation. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544627 Wed, 28 Dec 2011 09:00:33 +0100 5544627 http://www.medworm.com/index.php?rid=5544626&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10616.x Conclusions  Treatment with 311‐nm UVB accelerates the clearance of psoriatic lesions in ustekinumab‐treated patients. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544626 Wed, 28 Dec 2011 09:00:23 +0100 5544626 http://www.medworm.com/index.php?rid=5544625&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10537.x Conclusions  Transgrediens involvement of the dorsal feet is a rare manifestation of mutation‐confirmed PC and may be more common in patients who carry a KRT6A mutation. Trauma, friction, infection and wound healing may exacerbate or predispose toward transgrediens lesions. It remains to be proven whether transgrediens‐associated infection is causal or represents a primary or secondary process. Patients with PC who develop transgrediens lesions may benefit from fungal and bacterial cultures, followed by appropriate antimicrobial treatments. Efforts to decrease skin friction and moisture may also improve and/or prevent transgrediens spread. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544625 Wed, 28 Dec 2011 09:00:18 +0100 5544625 http://www.medworm.com/index.php?rid=5544624&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10598.x Conclusions  Our results support the hypothesis that the origin of facial red fluorescence is sebum. In patients with acne, analyses of the pattern and proportion of UV‐induced red fluorescence can be useful for evaluating the sebum secretion and selecting efficient treatment modalities. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544624 Wed, 28 Dec 2011 09:00:04 +0100 5544624 http://www.medworm.com/index.php?rid=5544623&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10761.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544623 Wed, 28 Dec 2011 08:59:53 +0100 5544623 http://www.medworm.com/index.php?rid=5544622&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10760.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544622 Wed, 28 Dec 2011 08:59:51 +0100 5544622 http://www.medworm.com/index.php?rid=5544621&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10759.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544621 Wed, 28 Dec 2011 08:59:49 +0100 5544621 http://www.medworm.com/index.php?rid=5544620&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10754.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544620 Wed, 28 Dec 2011 08:59:48 +0100 5544620 http://www.medworm.com/index.php?rid=5544619&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10740.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544619 Wed, 28 Dec 2011 08:59:46 +0100 5544619 http://www.medworm.com/index.php?rid=5544618&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10680.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544618 Wed, 28 Dec 2011 08:59:45 +0100 5544618 http://www.medworm.com/index.php?rid=5544617&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10737.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544617 Wed, 28 Dec 2011 08:59:43 +0100 5544617 http://www.medworm.com/index.php?rid=5544616&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10679.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544616 Wed, 28 Dec 2011 08:59:42 +0100 5544616 http://www.medworm.com/index.php?rid=5544615&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10753.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544615 Wed, 28 Dec 2011 08:59:40 +0100 5544615 http://www.medworm.com/index.php?rid=5544614&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10769.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5544614 Wed, 28 Dec 2011 08:59:38 +0100 5544614 http://www.medworm.com/index.php?rid=5552370&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10797.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552370 Wed, 28 Dec 2011 05:00:00 +0100 5552370 http://www.medworm.com/index.php?rid=5552369&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10798.x Conclusions:  These results suggest that the T allele of rs10249788 located in the promoter of the AHR gene is associated with protective effect on vitiligo in Han Chinese populations. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552369 Wed, 28 Dec 2011 05:00:00 +0100 5552369 http://www.medworm.com/index.php?rid=5552368&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10799.x Conclusions:  The findings have important theoretical and clinical implications for psychological management of patients with psoriasis and eczema. Treatment protocols may benefit by targeting schemas. Further studies are needed to investigate the benefits of schema‐focused therapy in patients with skin disease. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552368 Wed, 28 Dec 2011 05:00:00 +0100 5552368 http://www.medworm.com/index.php?rid=5524755&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10788.x Conclusion:  Our results indicate that FGFR3, PIK3CA and RAS mutations are present in approximately 50% of BLK. These findings support the concept on the molecular genetic level that at least a proportion of BLK represent regressive variants resulting from former benign epidermal tumours such as seborrheic keratosis and solar lentigo. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524755 Wed, 21 Dec 2011 05:00:00 +0100 5524755 http://www.medworm.com/index.php?rid=5524754&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10790.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524754 Wed, 21 Dec 2011 05:00:00 +0100 5524754 http://www.medworm.com/index.php?rid=5524753&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10791.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524753 Wed, 21 Dec 2011 05:00:00 +0100 5524753 http://www.medworm.com/index.php?rid=5524752&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10792.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524752 Wed, 21 Dec 2011 05:00:00 +0100 5524752 http://www.medworm.com/index.php?rid=5524751&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10793.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524751 Wed, 21 Dec 2011 05:00:00 +0100 5524751 http://www.medworm.com/index.php?rid=5524762&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10775.x Conclusions:  WBI‐1001 is an efficacious novel topical anti‐inflammatory molecule for the treatment of atopic dermatitis. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524762 Mon, 19 Dec 2011 05:00:00 +0100 5524762 http://www.medworm.com/index.php?rid=5524761&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10776.x We report a case of MMP in a 67‐year‐old man. Clinical examination revealed extensive mucosal lesions as well as generalized blisters and erosions that healed with scar formation. He was intractable with systemic steroid treatment. Interestingly, in addition to IgG directed against laminin‐332 and the noncollagenous 16A (NC16A) and C‐terminal domains of COL17, circulating IgA reacted with laminin‐332 and with the NC16A domain of COL17 were also detected. This is the first MMP case with circulating IgA and IgG autoantibodies against both laminin‐332 and COL17. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524761 Mon, 19 Dec 2011 05:00:00 +0100 5524761 http://www.medworm.com/index.php?rid=5524760&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10777.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524760 Mon, 19 Dec 2011 05:00:00 +0100 5524760 http://www.medworm.com/index.php?rid=5524759&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10778.x Conclusions:  When assessing psoriasis treatments and making decisions about treatment guidelines and resource allocation, EQ‐5D, DLQI and PASI provide a useful set of complementary tools, answering to different needs. If EQ‐5D is not included in the original trial the second best option in cost‐effectiveness studies is to use mapping between DLQI and EQ‐5D. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524759 Mon, 19 Dec 2011 05:00:00 +0100 5524759 http://www.medworm.com/index.php?rid=5524758&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10779.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524758 Mon, 19 Dec 2011 05:00:00 +0100 5524758 http://www.medworm.com/index.php?rid=5524757&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10780.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524757 Mon, 19 Dec 2011 05:00:00 +0100 5524757 http://www.medworm.com/index.php?rid=5524756&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10781.x Conclusions:  Our data suggests that reporting resin concentration in petrolatum is not predictive of a consistent concentration of the two main allergens of PTBP‐FR. The ten‐fold difference in allergen concentration between different patch test preparations has significant ramifications for maintaining consistent dose of delivered allergen. The results of this study reinforce the need for patch test product standardization in the Contact Dermatitis community. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524756 Mon, 19 Dec 2011 05:00:00 +0100 5524756 http://www.medworm.com/index.php?rid=5515427&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10771.x Conclusions:  PH, LTB4 and 8‐isoprostane in EBC could be sensitive markers of airway inflammation in AD children. Prospective studies would be of interest to evaluate if airway inflammation, not yet clinically evident, could predict the development of asthma later in life in children with AD. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5515427 Sat, 17 Dec 2011 05:00:00 +0100 5515427 http://www.medworm.com/index.php?rid=5515426&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10772.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5515426 Sat, 17 Dec 2011 05:00:00 +0100 5515426 http://www.medworm.com/index.php?rid=5515425&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10773.x Conclusions:  Patients with CLE appear to have an elevated risk for certain cancer types, an increase that remains when excluding patients also diagnosed with systemic lupus erythematosus. Our findings point to the importance of counselling about non‐smoking and sun‐avoidance and underscore the need for specialised monitoring of this patient group along with bench‐to‐bedside research efforts to clarify pathogenesis. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5515425 Sat, 17 Dec 2011 05:00:00 +0100 5515425 http://www.medworm.com/index.php?rid=5469069&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10764.x Conclusions:  The results demonstrated that heavy ion radiotherapy offers high local tumor control and progression‐free survival rates without significant radiation‐induced toxicity for patients with skin carcinomas. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469069 Fri, 02 Dec 2011 05:00:00 +0100 5469069 http://www.medworm.com/index.php?rid=5469068&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10763.x Conclusions:  Combined vaccination with hkBCG and Ag85B decreases AD skin lesions by inducing regulatory T cells; suggesting that this vaccination as a potent and novel therapeutic strategy for AD. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469068 Fri, 02 Dec 2011 05:00:00 +0100 5469068 http://www.medworm.com/index.php?rid=5469067&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10766.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469067 Fri, 02 Dec 2011 05:00:00 +0100 5469067 http://www.medworm.com/index.php?rid=5524750&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10794.x AbstractGranulomatous cheilitis (GC) is a poorly understood disease process belonging to the larger group of orofacial granulomatosis. The treatment of GC has proven exceedingly difficult. While a variety of treatments have been applied to GC, there has been no uniform or predictably successful model demonstrated in the literature. The poorly understood etiologic mechanisms underpinning GC has significantly hampered the development an effective approach to treatment. Those therapies that have shown promise principally consist of agents with anti‐inflammatory activity such as corticosteroids and immunomodulatory medications. On a careful review of the literature, we have found no systematic review and assessment of current treatments. We seek to address this absence in the available liter... British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5524750 Thu, 01 Dec 2011 05:00:00 +0100 5524750 http://www.medworm.com/index.php?rid=5515424&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10774.x Conclusions:  Psoriasis is an independent predictor for non‐fatal CVD among women, with particularly high risk for those with longer duration of psoriasis and concomitant psoriatic arthritis. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5515424 Thu, 01 Dec 2011 05:00:00 +0100 5515424 http://www.medworm.com/index.php?rid=5469066&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10765.x Conclusions:  Our observations raise the question as to whether excessive secretion of AMPs by the skin, in particular by the apocrine sweat glands, distal hair follicle epithelium, and epidermis may attract inflammation and thus facilitate or promote HS development. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469066 Thu, 01 Dec 2011 05:00:00 +0100 5469066 http://www.medworm.com/index.php?rid=5457826&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10758.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457826 Thu, 01 Dec 2011 05:00:00 +0100 5457826 http://www.medworm.com/index.php?rid=5457829&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10755.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457829 Mon, 28 Nov 2011 05:00:00 +0100 5457829 http://www.medworm.com/index.php?rid=5457828&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10756.x We describe 3 novel mutations in EBP gene. EBP mutations were inherited in 3 out 9 families and were sporadic in the rest of cases. A skewed X‐chromosome inactivation may explain the clinical phenotype in CDPX2 in some familial cases. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457828 Mon, 28 Nov 2011 05:00:00 +0100 5457828 http://www.medworm.com/index.php?rid=5457827&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10757.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457827 Mon, 28 Nov 2011 05:00:00 +0100 5457827 http://www.medworm.com/index.php?rid=5441118&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10671.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441118 Fri, 25 Nov 2011 05:46:13 +0100 5441118 http://www.medworm.com/index.php?rid=5441117&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10719.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441117 Fri, 25 Nov 2011 05:46:11 +0100 5441117 http://www.medworm.com/index.php?rid=5441116&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10609.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441116 Fri, 25 Nov 2011 05:46:10 +0100 5441116 http://www.medworm.com/index.php?rid=5441115&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10531.x Conclusions  Long‐term low‐dose MTX combined with short‐term STS may result in protracted control of BP in carefully selected patients. These results should prompt randomized controlled trials comparing this treatment with the more usual regimen of long‐term STS alone. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441115 Fri, 25 Nov 2011 05:45:58 +0100 5441115 http://www.medworm.com/index.php?rid=5441114&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10567.x Conclusions  The spectrum of changes in BMM is distinctive, and BMM can be differentiated with surety from both PD and VIN with mucinous differentiation. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441114 Fri, 25 Nov 2011 05:45:44 +0100 5441114 http://www.medworm.com/index.php?rid=5441113&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10614.x Conclusions  Treatment with the 1450 nm laser does not reduce inflammatory lesion count or acne grade when compared with a control side, using a split‐face format in participants recruited from secondary care. Both sides of the face improved and a systemic effect of the laser is possible. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441113 Fri, 25 Nov 2011 05:45:42 +0100 5441113 http://www.medworm.com/index.php?rid=5441112&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10565.x Conclusions  We present one of the largest PG case series to date. In our study, we found that biopsy of a PG lesion rarely yielded characteristic features of the disease and tissue pathology should not be used to exclude a PG diagnosis. We also found a female predominance and associations with IBD and haematological disorders. Patients with PG in this series had high rates of depression and hepatitis. Further work is needed to establish the mechanism(s) underlying these findings. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441112 Fri, 25 Nov 2011 05:45:39 +0100 5441112 http://www.medworm.com/index.php?rid=5441111&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10599.x Conclusions  NOS 2 is significantly involved in angiogenic signalling in healing skin wounds, particularly within the first 7 days. However, Matrigel plug vascularization suggests that the role of NOS 2 in angiogenesis is related to VEGF‐A but not FGF‐2 stimulated angiogenesis. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441111 Fri, 25 Nov 2011 05:45:36 +0100 5441111 http://www.medworm.com/index.php?rid=5441110&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10561.x Conclusions  The finding of NPs in tattoo inks in general usage is new and may contribute to the understanding of tattoo ink kinetics. How the body responds to NP tattoo pigments should be examined further. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441110 Fri, 25 Nov 2011 05:45:33 +0100 5441110 http://www.medworm.com/index.php?rid=5441109&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10506.x Conclusions  The results of this study suggest that MT1‐MMP might be a novel marker for high‐risk BCC. In addition, expression of both β‐catenin and MT1‐MMP was increased in high‐risk BCC tumour cells, indicating that these two proteins may play an important role in locally invasive and highly destructive growth behaviour of high‐risk BCCs. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441109 Fri, 25 Nov 2011 05:45:29 +0100 5441109 http://www.medworm.com/index.php?rid=5441108&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10532.x Conclusions  The impact of dermatological diseases is high for the mental components of health status; the mean scores for MCS‐12 were low, and lower in patients identified as GHQ‐12 ‘cases’. The picture of the general health status of patients with skin diseases given by the SF‐12 allows meaningful comparisons both within dermatological conditions and with diseases in other specialties, as well as within categories of clinical severity and psychological well‐being in single skin conditions. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441108 Fri, 25 Nov 2011 05:45:28 +0100 5441108 http://www.medworm.com/index.php?rid=5441107&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10677.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441107 Fri, 25 Nov 2011 05:45:20 +0100 5441107 http://www.medworm.com/index.php?rid=5441106&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10724.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441106 Fri, 25 Nov 2011 05:45:19 +0100 5441106 http://www.medworm.com/index.php?rid=5441105&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10653.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441105 Fri, 25 Nov 2011 05:45:17 +0100 5441105 http://www.medworm.com/index.php?rid=5441104&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10589.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441104 Fri, 25 Nov 2011 05:45:16 +0100 5441104 http://www.medworm.com/index.php?rid=5441103&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10718.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5441103 Fri, 25 Nov 2011 05:45:14 +0100 5441103 http://www.medworm.com/index.php?rid=5431791&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10742.x Conclusion:  Since evidences have shown the efficacy of enzyme replacement therapy in halting the progression of disease before the onset of irreversible organ damage, it is advisable to aim at an early diagnosis in order to achieve timely initiation of effective treatment with benefits for patients and appropriate use of medical resources. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431791 Sat, 19 Nov 2011 05:00:00 +0100 5431791 http://www.medworm.com/index.php?rid=5431790&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10743.x Conclusion:  This systematic review demonstrated epidemiologic and prognostic differences between Ewing’s sarcoma of the bone and primary cutaneous Ewing’s sarcoma. Primary cutaneous Ewing’s sarcoma has female predominance, occurs at a later age, but, more importantly, has a better outcome. Multimodal therapy for Ewing’s sarcoma is associated with immediate and long‐term morbidity and mortality. Although the size of our study does not allow definitive conclusion about treatment modalities, we suggest that a less toxic approach compared to conventional treatment should be investigated in primary cutaneous Ewing’s sarcoma. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431790 Sat, 19 Nov 2011 05:00:00 +0100 5431790 http://www.medworm.com/index.php?rid=5431789&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10744.x Conclusions:  While there is significant phenotypic overlap among syndromes of the Ras/MAPK pathway, individuals with CS are more likely than individuals with CFC syndrome to present with cutaneous papillomas, palmoplantar keratoderma and full eyebrows, and are less likely to present with ulerythema ophryogenes, keratosis pilaris or multiple naevi. The dermatologic features of CS, a Ras dysregulation syndrome, share many features with cutaneous paraneoplastic syndromes. This may provide further insight into the role of Ras signaling in cutaneous paraneoplastic syndromes. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431789 Sat, 19 Nov 2011 05:00:00 +0100 5431789 http://www.medworm.com/index.php?rid=5431788&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10745.x Conclusion:  Phenotypic differences between patients with K6a and K16 mutations support adoption of a new classification system based on the mutant gene (PC‐6a, PC‐16) rather than the PC‐1 nomenclature. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431788 Sat, 19 Nov 2011 05:00:00 +0100 5431788 http://www.medworm.com/index.php?rid=5431787&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10746.x Conclusions:  Proteins produced by a bacterium isolated from a Demodex mite have the ability to increase the migration, degranulation and cytokine production abilities of neutrophils. These results suggest that bacteria may play a role in the inflammatory erythema associated with rosacea. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431787 Sat, 19 Nov 2011 05:00:00 +0100 5431787 http://www.medworm.com/index.php?rid=5431785&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10747.x Conclusion:  In similarity to a previous study, CoNS were the most common bacteria, but in contrary to what we expected, Staphylococcus aureus was not found in any cultures from acute inflammatory nodules of HS exacerbation. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431785 Sat, 19 Nov 2011 05:00:00 +0100 5431785 http://www.medworm.com/index.php?rid=5431784&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10748.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431784 Sat, 19 Nov 2011 05:00:00 +0100 5431784 http://www.medworm.com/index.php?rid=5431783&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10749.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431783 Sat, 19 Nov 2011 05:00:00 +0100 5431783 http://www.medworm.com/index.php?rid=5431782&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10750.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431782 Sat, 19 Nov 2011 05:00:00 +0100 5431782 http://www.medworm.com/index.php?rid=5431781&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10751.x Conclusion:  Nd:YAG laser therapy is effective in the treatment of mucocutaneous lesions in patients suffering from Blue Rubber Bleb Nevus Syndrome. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431781 Sat, 19 Nov 2011 05:00:00 +0100 5431781 http://www.medworm.com/index.php?rid=5408158&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10732.x Conclusion:  The present findings show that the combination of IA and Rtx induces rapid clinical remission and long‐term control in difficult to treat pemphigus. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408158 Wed, 16 Nov 2011 05:00:00 +0100 5408158 http://www.medworm.com/index.php?rid=5408157&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10733.x Conclusions:  The prevalence of food avoidance was high and mostly ineffective in Chinese patients with chronic urticaria. Foods avoided did not correspond to serum food‐specific IgE. The incidence of IgE‐mediated urticaria, as demonstrated by open food challenge, is low. Physicians and patients should be aware of unnecessary dietary avoidance while seeking treatment of chronic urticaria. (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408157 Wed, 16 Nov 2011 05:00:00 +0100 5408157 http://www.medworm.com/index.php?rid=5408156&cid=s_31732_12_f&fid=31732&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2133.2011.10734.x (Source: British Journal of Dermatology) British Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408156 Wed, 16 Nov 2011 05:00:00 +0100 5408156