MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Cancer Cytopathology' source. Thu, 09 Feb 2012 00:42:08 +0100 http://www.medworm.com/index.php?rid=5651031&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.21185 CONCLUSIONS:Diagnostic pitfalls include pancreatic neuroendocrine tumor. If IPAS is recognized as a diagnostic consideration on EUS‐FNA, unnecessary surgical resection may be avoided. Cancer (Cancer Cytopathol) 2012. © 2012 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5651031 Wed, 01 Feb 2012 05:00:00 +0100 5651031 http://www.medworm.com/index.php?rid=5651030&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.21184 CONCLUSION:This study demonstrates that both arginase‐1 and HepPar‐1 are effective IHC markers of hepatocellular differentiation. Furthermore, arginase‐1 demonstrates superior sensitivity compared with GPC‐3 and HepPar‐1 in the diagnosis of HCC, whereas GPC‐3 demonstrates superior specificity, as staining is not observed in benign hepatocellular lesions. Hence, use of arginase‐1 with HepPar‐1 and GPC‐3 can aid in the diagnosis of HCC and separating from metastatic carcinoma. Cancer (Cancer Cytopathol) 2012. © 2012 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5651030 Wed, 01 Feb 2012 05:00:00 +0100 5651030 http://www.medworm.com/index.php?rid=5630919&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20205 CONCLUSIONS:High molecular weight DNA was extracted from the cards in sufficient amounts and quality to perform high‐throughput multiplex mutation assays. The results of the current study also suggest that FTA Classic cards preserve better DNA integrity for molecular applications compared with the FTA Elute cards. Cancer (Cancer Cytopathol) 2012. © 2012 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5630919 Tue, 24 Jan 2012 05:00:00 +0100 5630919 http://www.medworm.com/index.php?rid=5651029&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20206 CONCLUSIONS:Alcohol‐based fixation seems not to affect the immunocytochemical evaluation of HR and HER2. Considering the high levels of agreement between the evaluation of HR and HER2, on both cytology specimens and on the corresponding FFPE tissue samples, the authors concluded that the TP technique can be routinely used for the biological characterization of IBC. Cancer (Cancer Cytopathol) 2012. © 2012 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5651029 Sun, 25 Dec 2011 05:00:00 +0100 5651029 http://www.medworm.com/index.php?rid=5630918&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20207 The evaluation of circulating tumor cells in peripheral blood of patients with breast cancer can be performed using different platforms. Standardization and comparison of the platforms to each other and their use in prospective clinical trials is needed for incorporation of circulating tumor cell assays into clinical practice. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5630918 Sun, 25 Dec 2011 05:00:00 +0100 5630918 http://www.medworm.com/index.php?rid=5507268&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20204 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5507268 Fri, 16 Dec 2011 17:40:56 +0100 5507268 http://www.medworm.com/index.php?rid=5478661&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20199 CONCLUSIONS:The data from the current study demonstrate that the TCC‐CB method significantly increases the cellular yield of CB preparations without compromising cytomorphological characterization of tumor cells. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5478661 Tue, 25 Oct 2011 04:00:00 +0100 5478661 http://www.medworm.com/index.php?rid=5411557&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20198 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5411557 Tue, 25 Oct 2011 04:00:00 +0100 5411557 http://www.medworm.com/index.php?rid=5366931&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20197 The objective of this review was to address the use of immunocytochemistry and molecular techniques to refine the preoperative diagnosis and classification of lung cancer, thyroid cancer, kidney cancer, gastrointestinal cancer, and soft tissue tumors. Fine‐needle aspiration also offers a suitable alternative to biopsy in a variety of clinical settings, in particular, when it may be useful to obtain material to study prognostic and predictive markers. This is particularly relevant to obtain material from metastatic sites. The study of KRAS in colon cancer, CKIT in gastrointestinal stromal tumors, and epidermal growth factor receptor mutational status in lung cancer also are addressed particularly in this report. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: C... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5366931 Tue, 25 Oct 2011 04:00:00 +0100 5366931 http://www.medworm.com/index.php?rid=5325887&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20196 The author discusses the importance of human papillomavirus testing, the selection of assay type, and assay validation. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5325887 Wed, 19 Oct 2011 03:28:27 +0100 5325887 http://www.medworm.com/index.php?rid=5317317&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20195 CONCLUSIONS:Use of either the 5‐tiered or 6‐tiered reporting systems for thyroid FNA specimens can potentially affect the clinical management of patients with thyroid nodules. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5317317 Sat, 15 Oct 2011 19:28:57 +0100 5317317 http://www.medworm.com/index.php?rid=5306538&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20194 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5306538 Wed, 12 Oct 2011 17:31:12 +0100 5306538 http://www.medworm.com/index.php?rid=5306537&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20193 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5306537 Wed, 12 Oct 2011 17:31:10 +0100 5306537 http://www.medworm.com/index.php?rid=5240981&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20190 Conclusions:Rapid prescreening is more effective than 100% rapid review for the detection of false‐negatives at routine screening, thus providing subsidies for the performance of cervical cytology, the principal function of which is to detect precursor lesions of cervical cancer. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5240981 Thu, 22 Sep 2011 04:00:00 +0100 5240981 http://www.medworm.com/index.php?rid=5228665&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20192 CONCLUSIONS:Based on available studies, an AUS:M ratio of 1.0 to 3.0 is recommended. AUS:M ratios > 3.0 are likely because of overdiagnosis of AUS or underdiagnosis of M. AUS:M ratios < 1.0 are mostly due to low AUS rates, at the likely expense of sensitivity. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5228665 Wed, 14 Sep 2011 04:00:00 +0100 5228665 http://www.medworm.com/index.php?rid=5186252&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20183 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5186252 Tue, 30 Aug 2011 23:00:00 +0100 5186252 http://www.medworm.com/index.php?rid=5186251&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20186 AbstractThe Bethesda system for standardized reporting of thyroid fine needle aspiration (FNA) cytology has positively affected the clarity of communication of results and management of patients evaluated for thyroid nodules. Problematic areas still exist in the triage of some of these samples, particularly those in the categories of “follicular lesion with atypia of uncertain significance” and “follicular lesion.” The literature on molecular and genetic abnormalities in thyroid lesions is reviewed. Potentially useful markers for distinguishing currently problematic categories of FNA cytologic samples, especially nondiagnostic samples, atypia of uncertain significance, and follicular lesions, are discussed. The predictive value of the respective molecular analyses in these settings... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5186251 Tue, 30 Aug 2011 23:00:00 +0100 5186251 http://www.medworm.com/index.php?rid=5240980&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20189 AbstractNo abtract. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5240980 Thu, 25 Aug 2011 04:00:00 +0100 5240980 http://www.medworm.com/index.php?rid=5228664&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20191 The atypical follicular cell diagnosis in the new Bethesda System for Reporting Thyroid Cytopathology is a heterogeneous category without well‐defined cellular criteria and has the potential for overuse. Laboratories should monitor the use of this diagnosis.See also pages 000‐000. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5228664 Thu, 25 Aug 2011 04:00:00 +0100 5228664 http://www.medworm.com/index.php?rid=5186249&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20184 CONCLUSIONS:Cytotechnologists are almost always correct when assessing initial FNAB samples as adequate. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5186249 Wed, 24 Aug 2011 23:00:00 +0100 5186249 http://www.medworm.com/index.php?rid=5164991&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20185 CONCLUSIONS:In liquid‐based preparations, distinctive cytological features of pulmonary adenocarcinoma correlate with levels of histological differentiation and can be combined into a score with prognostic significance. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5164991 Wed, 24 Aug 2011 23:00:00 +0100 5164991 http://www.medworm.com/index.php?rid=5164990&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20187 Conclusions:In conclusion, our study seems to demonstrate a favorable performance of FPGS in the routine clinical setting. FPGS may have the potential to be a promising screening tool for gynecologic cytology in a low‐risk patient population. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5164990 Wed, 24 Aug 2011 23:00:00 +0100 5164990 http://www.medworm.com/index.php?rid=5164989&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20188 CONCLUSIONS:Dual staining for p16INK4a/Ki‐67 immunocytochemistry dramatically increased specificity and maintained high‐level sensitivity for the diagnosis of CIN2/3 or glandular lesions compared with PCR‐based testing for HR‐HPV. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5164989 Wed, 24 Aug 2011 23:00:00 +0100 5164989 http://www.medworm.com/index.php?rid=5121481&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20182 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5121481 Fri, 12 Aug 2011 23:52:16 +0100 5121481 http://www.medworm.com/index.php?rid=5043083&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20173 CONCLUSIONS:Poorly differentiated tumors with few stromal components and low numbers of differentiating/mature cells were found to be MYCN amplified. The authors propose a “cytology prognostic score” in which neuroblastomas comprised of predominantly neuroblastic elements with no differentiating cells and an MKI >; 2% are classified as high‐risk tumors, regardless of their MYCN amplification status. The use of this proposed score would ensure accurate and optimal diagnostic and prognostic classifications of neuroblastic tumors in cases in which the histological biopsy is absent or inadequate for analysis. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5043083 Mon, 18 Jul 2011 23:00:00 +0100 5043083 http://www.medworm.com/index.php?rid=5043082&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20177 CONCLUSIONS:Both methods yielded similar validity in detecting significant cervical lesions. However, SurePath samples yielded higher rates of satisfactory LBC slides and sufficient residual volume for HC2. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5043082 Mon, 18 Jul 2011 23:00:00 +0100 5043082 http://www.medworm.com/index.php?rid=5023223&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20181 CONCLUSIONS:CB combined with LBC was found to improve the rate of detection of malignancy over LBC alone, especially in cases with suspicious or atypical LBC diagnoses. Increased diagnostic yield is observed when CB is used with or without ancillary studies, but the yield is higher with CB using ancillary studies. CB serves as yet another available source of diagnostic material for immunohistochemical and molecular studies. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5023223 Mon, 11 Jul 2011 23:00:00 +0100 5023223 http://www.medworm.com/index.php?rid=5023222&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20179 CONCLUSIONS:Qualified cytologic diagnosis increases the effectiveness of FNA, forgoing the need for repeat biopsy or intraoperative frozen section evaluation. Preoperative BRAF mutation testing can supplement the routine cytology in the selection of thyroid nodules for surgery. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5023222 Mon, 11 Jul 2011 23:00:00 +0100 5023222 http://www.medworm.com/index.php?rid=5023221&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20178 AbstractThyroid fine‐needle aspiration has developed into a key test in the evaluation of thyroid nodules. Although the interpretation of thyroid aspirates containing mild abnormalities is problematic, the introduction of the atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) category in The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) has helped to delineate such cases in a systematic and clinically meaningful manner. Herein the authors review the cytomorphologic features associated with the AUS/FLUS interpretation and summarize the results of studies conducted since the implementation of TBSRTC. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5023221 Mon, 11 Jul 2011 23:00:00 +0100 5023221 http://www.medworm.com/index.php?rid=5023220&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20175 CONCLUSIONS:The Hybrid Capture 2 strategy, already widely used for the detection of high‐risk HPV in cervical brushes, is readily transferrable to HNSCCs. Consistent accuracy in cytologic preparation suggests its potential application in FNAs from patients who present with lymph node metastases, and may eliminate the need to obtain tissue solely for the purpose of HPV testing. Cancer (Cancer Cytopathol) 2011; . © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5023220 Mon, 11 Jul 2011 23:00:00 +0100 5023220 http://www.medworm.com/index.php?rid=5001872&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20172 CONCLUSIONSUsing 1 RLU/CO as the cutoff value, HR HPV testing was found to be highly sensitive for detecting CIN 2+ lesions in women with LSIL. The colposcopy rate was significantly lower in women aged ≥ 30 years compared with women aged < 30 years. Triaging with HR HPV testing may be indicated in women aged ≥ 30 years with LSIL cytology, but not in women aged < 30 years. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5001872 Mon, 04 Jul 2011 23:00:00 +0100 5001872 http://www.medworm.com/index.php?rid=5001871&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20171 CONCLUSIONS:Chromosomal aberrations can occur in reactive urothelial cells, with a tetraploid pattern being the most common. Even an aneuploid pattern of FISH signals does not always prove malignancy because it rarely occurs in reactive urothelial cells. Correlation of FISH results with cytomorphology and patient history is crucial to avoid false‐positive diagnoses. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5001871 Mon, 04 Jul 2011 23:00:00 +0100 5001871 http://www.medworm.com/index.php?rid=5001870&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20165 In this study, overall improvement appeared to be driven largely by improvement in preanalytic Papanicolaou (Pap) test sampling, because longer institutional participation also was associated with improved sampling sensitivity. The authors hypothesized that Pap test sampling may have improved secondary to the introduction of liquid‐based technology, which was implemented in many laboratories during the study time frame. Through the performance of continuous data tracking and retrospective root cause analysis to identify factors that may have influenced any observed changes in performance indicators, institutions may learn which initiatives are successful or unsuccessful. The future of correlation lies in the standardization of methods, the development of more formal and rigorous root cau... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5001870 Mon, 04 Jul 2011 23:00:00 +0100 5001870 http://www.medworm.com/index.php?rid=4979023&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20168 CONCLUSIONS:Given the lack of statistically significant differences with regard to FISH and cystoscopy results, the authors propose that FISH could be a useful monitoring tool in the surveillance of patients with a previous history of NMIUCC. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4979023 Tue, 28 Jun 2011 23:00:00 +0100 4979023 http://www.medworm.com/index.php?rid=4979022&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20167 CONCLUSIONS:The results of the current study demonstrated that FFPE cell blocks from cytologic body fluid specimens yield adequate diagnostic material for the Pathwork test and can be used in the workup of patients with unknown primary tumors. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4979022 Tue, 28 Jun 2011 23:00:00 +0100 4979022 http://www.medworm.com/index.php?rid=4979021&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20166 AbstractThe evaluation of mediastinal and hilar lymph nodes for tissue diagnosis and staging of lung cancer is now commonly performed by minimally invasive, nonsurgical procedures such as computed tomography‐guided fine‐needle aspiration and endobronchial ultrasound‐guided transbronchial needle aspiration. Ensuring that a sufficient quantity of cellular material has been acquired to enable multiple studies has become a priority issue in the era of personalized medicine, especially for patients with lung cancer, and this can be accomplished by rapid onsite evaluation (ROSE). This commentary focuses on the use of ROSE in guided procedures, especially for hilar and mediastinal lymph node aspirates, and describes an algorithm for handling these specimens. Cancer (Cancer Cytopathol) 2011;... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4979021 Tue, 28 Jun 2011 23:00:00 +0100 4979021 http://www.medworm.com/index.php?rid=4979020&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20162 CONCLUSIONS:Immunostaining of bronchial brushings fixed with CytoRich Red was useful in determining histologic types in NSCLC. It was suggested that the panels of Napsin A, TTF‐1, and p63 were effective in identifying histologic type in NSCLC, and that a combination of either Napsin A and p63 or TTF‐1 and p63 should be chosen, depending on morphology. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4979020 Tue, 28 Jun 2011 23:00:00 +0100 4979020 http://www.medworm.com/index.php?rid=5065412&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20180 CONCLUSIONS:Cytologic direct smears represent a robust and valuable source of cellular material for immunocytochemistry and molecular studies, especially in instances in which inadequate cell block cellularity is anticipated or encountered. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5065412 Fri, 24 Jun 2011 23:00:00 +0100 5065412 http://www.medworm.com/index.php?rid=5043081&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20176 CONCLUSIONS:hrHPV was detected in LBC vials from 96.2% of 338 cervical HSIL and 85.7% of 14 vaginal HSIL. CIN2/3+ was significantly more likely with hrHPV‐positive cervical HSIL than with hrHPV‐negative cervical HSIL. Presence or absence of an EC/TZS did not significantly impact HSIL hrHPV or CIN2/3+ rates. Some hrHPV‐negative HSIL cases may represent HSIL cytologic mimics. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5043081 Fri, 24 Jun 2011 23:00:00 +0100 5043081 http://www.medworm.com/index.php?rid=5023219&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20174 CONCLUSIONS:Implementation of TBSRTC appears to improve the quality of reporting by lowering the number of ambiguous and implicit diagnoses and decreases the overall surgery rates, particularly for benign lesions, but it does not appear to have any effect on the accuracy of FNA of the thyroid, false‐positive rates, or the frequency of intraoperative consultations. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5023219 Fri, 24 Jun 2011 23:00:00 +0100 5023219 http://www.medworm.com/index.php?rid=5001869&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20164 CONCLUSIONS:MOC‐31 alone was found to be highly sensitive for distinguishing reactive mesothelial cells/mesothelioma from metastatic adenocarcinoma in effusion specimens. Interpreting membranous MOC‐31 staining as positive can help prevent confusion between reactive mesothelial cells/mesothelioma and metastatic adenocarcinoma. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=5001869 Fri, 24 Jun 2011 23:00:00 +0100 5001869 http://www.medworm.com/index.php?rid=4979019&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20161 AbstractHigh‐risk human papillomavirus (hrHPV) testing has become an integral component of cervical cancer screening, given that persistent infection with hrHPV was recognized as a significant risk factor for most precancers and cancers of the cervix. Particularly, testing for hrHPV types (in conjunction with cervical cytology) has been approved for primary screening in women over 30 years of age and for cost‐effective triaging of equivocal cervical cytology results. HPV was a small double‐stranded DNA virus that cannot be cultured in vitro; so, different types of tests have been developed to detect its presence. Various molecular techniques were available for detecting the presence and/or quantity of hrHPV. In this review, the testing options for hrHPV and its surrogates, with an em... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4979019 Fri, 24 Jun 2011 23:00:00 +0100 4979019 http://www.medworm.com/index.php?rid=4916074&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20170 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4916074 Fri, 10 Jun 2011 21:07:18 +0100 4916074 http://www.medworm.com/index.php?rid=4916073&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20169 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4916073 Fri, 10 Jun 2011 21:07:17 +0100 4916073 http://www.medworm.com/index.php?rid=4808108&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20160 CONCLUSIONS:No specific cytomorphologic feature(s) were found to reliably identify DHL using FNA or exfoliative cytology. A high Ki‐67 proliferation index and positive bcl‐2 staining (on cytospin slides or cell block material) of cases not conforming to typical Burkitt lymphoma morphology should prompt FISH analysis for c‐MYC and/or IGH‐BCL2 rearrangements to identify DHL, particularly if tissue biopsy is not expected. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4808108 Mon, 09 May 2011 23:00:00 +0100 4808108 http://www.medworm.com/index.php?rid=4791674&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20163 In the current and certainly future health care environment in the United States, the issue of more and better patient safety delivered in a cost‐effective and efficient manner will become an essential focus. This editorial reviews the concept of “information‐critical” data in anatomical pathology, both in histologic and cytologic diagnoses. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4791674 Thu, 05 May 2011 23:00:00 +0100 4791674 http://www.medworm.com/index.php?rid=4791673&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20159 Several published coding changes effective in 2011 will contribute to changes in cytopathology payments. A new code for the additional immediate evaluation of fine‐needle aspiration specimens is now operative and will be favorable to laboratories, whereas the new dedicated urine in situ hybridization codes will result in lower laboratory payments. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4791673 Thu, 05 May 2011 23:00:00 +0100 4791673 http://www.medworm.com/index.php?rid=4808107&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20156 CONCLUSIONS:Large cells with deeply basophilic cytoplasm, cytoplasmic vacuoles, and frequent segmented nuclei, particularly in fine needle aspirate smears and especially in patients with clinically aggressive and/or unusual clinical features, should trigger a fluorescence in situ hybridization analysis for IGH/BCL2 and MYC translocation to identify this entity. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4808107 Sun, 24 Apr 2011 23:00:00 +0100 4808107 http://www.medworm.com/index.php?rid=4791672&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20157 CONCLUSIONS:The current results suggested that FISH analysis of brush samples obtained noninvasively from suspicious laryngeal lesions can augment the clinical examination in predicting the nature of the lesions and can aid clinicians in monitoring and follow‐up of high‐risk patients. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4791672 Sun, 24 Apr 2011 23:00:00 +0100 4791672 http://www.medworm.com/index.php?rid=4737857&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20158 AbstractThe concept of critical values in the medical laboratory found its roots in clinical pathology nearly 40 years ago. The goal of this review was to trace the evolution of the critical value concept from clinical into anatomic pathology with specific emphasis on cytopathology. Difficulties in the meaningful application of the critical value concept in the practice of cytopathology are reviewed along with ambiguities that have yet to be fully resolved. Suggestions that may enhance the operational success of critical value policies in cytopathology and a central role for the cytotechnologist are presented. Cooperation between key pathology and clinical organizations is essential for improvement in the critical value process. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Soc... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4737857 Fri, 22 Apr 2011 21:34:58 +0100 4737857 http://www.medworm.com/index.php?rid=4706252&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20155 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4706252 Wed, 13 Apr 2011 22:28:42 +0100 4706252 http://www.medworm.com/index.php?rid=4633442&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20153 CONCLUSIONS:Immunocytochemical staining for GLUT1 and CAIX may be a complementary tool for the detection of malignant pleural effusions and is helpful in distinguishing cancer cells from reactive mesothelial cells. A combination of GLUT1 and CAIX immunocytochemical staining can give a higher diagnostic performance. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4633442 Fri, 25 Mar 2011 00:00:00 +0100 4633442 http://www.medworm.com/index.php?rid=4633441&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20139 Cervical cancer screening continues to evolve. We may be back to embracing morphology. See related article, pp, this issue. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4633441 Fri, 25 Mar 2011 00:00:00 +0100 4633441 http://www.medworm.com/index.php?rid=4633440&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20154 CONCLUSIONS:The majority of AUS cases in thyroid FNA can be subcategorized into 5 different patterns, all with associated significant risk of malignancy. “Atrophic” microfollicles are a significant risk factor for malignancy and should not be diagnosed as benign on the basis of lack of cytologic atypia. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4633440 Fri, 25 Mar 2011 00:00:00 +0100 4633440 http://www.medworm.com/index.php?rid=4633439&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20140 CONCLUSIONS:The results of this study show that p16/Ki‐67 dual‐stain cytology provided a high sensitivity for the detection of underlying CIN2+ in women with ASCUS or LSIL Pap cytology results, comparable to the rates previously reported for HPV testing and p16 single‐stain cytology. However, the specificity of this morphology‐independent interpretation of p16/Ki‐67 dual‐stain cytology testing was further improved compared with the earlier p16 single‐stain cytology approach, which required morphology interpretation, and it is significantly higher when compared with HPV testing. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4633439 Fri, 25 Mar 2011 00:00:00 +0100 4633439 http://www.medworm.com/index.php?rid=4633438&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20144 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4633438 Fri, 25 Mar 2011 00:00:00 +0100 4633438 http://www.medworm.com/index.php?rid=4618260&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20152 CONCLUSIONS:Image‐guided LN FNA is highly sensitive and specific for lymph node involvement by breast carcinoma and plays a role both in sparing sentinel lymph node biopsy and in triaging cases for systemic therapy. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4618260 Tue, 22 Mar 2011 00:00:00 +0100 4618260 http://www.medworm.com/index.php?rid=4597309&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20142 CONCLUSIONS:Thus, adjuvant FISH or DNA‐image cytometry in cytologically equivocal diagnoses improves diagnostic accuracy at comparable rates. Adjuvant QMSP in cytologically negative cases with persistent suspicion of lung cancer would enhance sensitivity. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4597309 Wed, 16 Mar 2011 00:00:00 +0100 4597309 http://www.medworm.com/index.php?rid=4572250&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20151 CONCLUSIONS:Our findings support clinical utilization of routinely prepared cytology specimens, including EBUS, CT/US. FNAs and body fluid specimens, as a reliable source for molecular testing to detect EGFR or KRAS mutations in patients with NSCLC. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4572250 Fri, 11 Mar 2011 00:00:00 +0100 4572250 http://www.medworm.com/index.php?rid=4572249&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20150 CONCLUSIONS:This analysis provided evidence that cytological material is suitable for detecting EGFR status using several different methodologies and preparations. New prospective, clinical studies are encouraged for collection and handling of cytological samples as well as for validation of novel techniques in large cohorts. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4572249 Fri, 11 Mar 2011 00:00:00 +0100 4572249 http://www.medworm.com/index.php?rid=4572248&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20149 CONCLUSIONS:DOG‐1 was the most sensitive and specific of the 3 markers for the diagnosis of GIST in cell‐block preparations and may be of particular use in the diagnosis of C‐Kit–negative GIST. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4572248 Fri, 11 Mar 2011 00:00:00 +0100 4572248 http://www.medworm.com/index.php?rid=4533875&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20141 The method of counting slides has changed, but the new counting method does not address evidence‐based data ensuring the safety of the established workload limits. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4533875 Tue, 01 Mar 2011 00:00:00 +0100 4533875 http://www.medworm.com/index.php?rid=4633437&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20146 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4633437 Fri, 25 Feb 2011 00:00:00 +0100 4633437 http://www.medworm.com/index.php?rid=4618259&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20147 AbstractHuman biospecimens are subjected to collection, processing, and storage that can significantly alter their molecular composition and consistency. These biospecimen preanalytical factors, in turn, influence experimental outcomes and the ability to reproduce scientific results. Currently, the extent and type of information specific to the biospecimen preanalytical conditions reported in scientific publications and regulatory submissions varies widely. To improve the quality of research that uses human tissues, it is crucial that information on the handling of biospecimens be reported in a thorough, accurate, and standardized manner. The Biospecimen Reporting for Improved Study Quality (BRISQ) recommendations outlined herein are intended to apply to any study in which human biospecime... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4618259 Fri, 25 Feb 2011 00:00:00 +0100 4618259 http://www.medworm.com/index.php?rid=4597308&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20145 CONCLUSIONS:This study demonstrated the value of an automated approach to the analysis of FISH slides, affording the benefit of high‐throughput while providing the user with the necessary images and tools to quickly and accurately report a case. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4597308 Fri, 25 Feb 2011 00:00:00 +0100 4597308 http://www.medworm.com/index.php?rid=4572247&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20148 CONCLUSIONS:The author concluded that a subset of papillary carcinomas of the thyroid were difficult to distinguish from Hürthle cell lesions or repair and/or cyst‐lining cells because of the presence of abundant granular cytoplasm and a lack of nuclear crowding. These tumors were often follicular or cystic variants of papillary carcinoma. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4572247 Fri, 25 Feb 2011 00:00:00 +0100 4572247 http://www.medworm.com/index.php?rid=4533874&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20143 CONCLUSIONS:There was no association between ICCp16 results and histopathological findings nor between ICCp16 and HPV genotyping. ICCp16 showed poor sensitivity and moderate specificity for the diagnosis of ASIL or high‐risk HPV. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4533874 Fri, 25 Feb 2011 00:00:00 +0100 4533874 http://www.medworm.com/index.php?rid=4479482&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20136 CONCLUSIONS:Pancreatic well‐differentiated neuroendocrine tumors frequently express PAX8, which can help distinguish pancreatic primary tumors from tumors of other anatomic sites. In contrast, PAX8 expression in poorly differentiated neuroendocrine carcinomas is not specific for pancreatic origin and can be seen in extrapancreatic poorly differentiated neuroendocrine carcinomas. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4479482 Tue, 15 Feb 2011 23:49:07 +0100 4479482 http://www.medworm.com/index.php?rid=4461656&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20138 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4461656 Fri, 11 Feb 2011 20:19:04 +0100 4461656 http://www.medworm.com/index.php?rid=4461655&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20137 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4461655 Fri, 11 Feb 2011 20:19:04 +0100 4461655 http://www.medworm.com/index.php?rid=4426072&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20135 CONCLUSIONS:The double IHC stain, TTF‐1/napsin A, for the identification of pulmonary adenocarcinoma in FNA cell block materials was diagnostically useful. The use of napsin A alone demonstrated a greater degree of accuracy and appeared diagnostically useful as a single IHC stain. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4426072 Tue, 01 Feb 2011 00:00:00 +0100 4426072 http://www.medworm.com/index.php?rid=4391089&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20133 CONCLUSIONS:This study suggests that cytological specimens from pancreatic cystic lesions obtained using EchoBrush at the time of EUS are superior to conventional EUS‐FNA mainly because of the higher yield of epithelial cells. Larger studies are needed to compare both methods. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4391089 Mon, 24 Jan 2011 00:00:00 +0100 4391089 http://www.medworm.com/index.php?rid=4452310&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20134 CONCLUSIONS:EBUS‐TBNA proved to be useful for evaluating mediastinal lymphadenopathy in patients with suspected lymphoproliferative disorders. Its use may decrease the need for invasive diagnostic procedures. Immediate assessment is valuable in these cases because of the need to triage material for immunophenotyping or other studies to determine optimal and clinically meaningful diagnoses. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4452310 Sat, 25 Dec 2010 00:00:00 +0100 4452310 http://www.medworm.com/index.php?rid=4426071&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20130 CONCLUSIONS:FNA specimens can be stored in a manner that maintains cellular morphology and RNA integrity necessary for studies of gene expression. In addition to addressing quality control (QC) and test validation needs, cytology banks will be an invaluable resource for future molecular morphologic and diagnostic research studies. Cancer (Cancer Cytopathol) 2011;. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4426071 Sat, 25 Dec 2010 00:00:00 +0100 4426071 http://www.medworm.com/index.php?rid=4391088&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20127 CONCLUSIONS:Because the appropriate selection of markers is crucial to successful analysis, the authors suggested a highly selected panel of antibodies for flow cytometry analysis of cerebrospinal fluid samples. The authors were able to demonstrate that leptomeningeal disease caused by leukemia or lymphoma can be diagnosed by flow cytometry and discriminated from reactive pleocytosis in most cases of doubtful morphology. Cancer (Cancer Cytopathol) 2011. © 2011 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4391088 Sat, 25 Dec 2010 00:00:00 +0100 4391088 http://www.medworm.com/index.php?rid=4283038&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20131 With the advent of newer, targeted therapies for lung cancer the role of the cytologist is also changing. More refined diagnoses are being demanded as well as information about the expression of specific aberrant proteins. Cytologists need to be cognizant of these changes and, in particular, that the generic diagnosis of nonsmall cell lung cancer is likely to need refinement for contemporary management. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4283038 Thu, 23 Dec 2010 20:42:42 +0100 4283038 http://www.medworm.com/index.php?rid=4269252&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20126 This article provides an overview of anal cancer screening while highlighting its differences from cervical cancer screening and the remaining obstacles and controversies to implementation of a successful anal cancer screening program. Cancer (Cancer Cytopathol) 2011;. © 2010 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4269252 Mon, 20 Dec 2010 00:36:33 +0100 4269252 http://www.medworm.com/index.php?rid=4269253&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20132 CONCLUSIONS:FNC is safe and useful in the diagnostic workup of pediatric patients with cutaneous nodules and has no contraindications to its use as the initial diagnostic procedure. Cancer (Cancer Cytopathol) 2011;. © 2010 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4269253 Fri, 17 Dec 2010 00:00:00 +0100 4269253 http://www.medworm.com/index.php?rid=4251813&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20119 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4251813 Mon, 13 Dec 2010 01:50:42 +0100 4251813 http://www.medworm.com/index.php?rid=4251811&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20129 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4251811 Mon, 13 Dec 2010 01:50:24 +0100 4251811 http://www.medworm.com/index.php?rid=4251810&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20128 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4251810 Mon, 13 Dec 2010 01:50:24 +0100 4251810 http://www.medworm.com/index.php?rid=4239739&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20125 CONCLUSIONS:The authors concluded that SurePath is a reliable technique for assessment of thyroid nodules and offers the advantage of easy identification of colloid and atypical nuclei. Supplementary frozen section analysis should be limited to an FNAC diagnosis of suspicious for papillary carcinoma. Cancer (Cancer Cytopathol) 2011. © 2010 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4239739 Tue, 07 Dec 2010 00:00:00 +0100 4239739 http://www.medworm.com/index.php?rid=4146586&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20122 AbstractSignificant numbers of overdiagnoses of thyroid needle biopsies as “indeterminate” create a risk of surgery for benign disease. Overdiagnoses can be reduced by appropriate criteria and a risk‐adapted approach to cytodiagnosis. Cancer (Cancer Cytopathol) 2010;. © 2010 American Cancer Society (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4146586 Mon, 08 Nov 2010 00:00:00 +0100 4146586 http://www.medworm.com/index.php?rid=4239738&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20124 CONCLUSIONS:TP as a sole preparatory technique does not improve the usefulness of T‐FNA as a screening test. However, combining CP and TP increases the rate of definitive cytologic diagnosis of malignancy in papillary thyroid carcinoma. Thus, combining TP and CP enhances the diagnostic component of T‐FNA. Cancer (Cancer Cytopathol) 2011. © 2010 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4239738 Mon, 25 Oct 2010 00:00:00 +0100 4239738 http://www.medworm.com/index.php?rid=4156892&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20123 CONCLUSIONS:EUS‐guided paracentesis is a valuable aid in the cytologic diagnosis of malignant ascites. It is particularly useful when no abnormality is identified by CT. Cancer (Cancer Cytopathol) 2010;. © 2010 American Cancer Society. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4156892 Mon, 25 Oct 2010 00:00:00 +0100 4156892 http://www.medworm.com/index.php?rid=4146585&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20121 CONCLUSIONS:The primary diagnosis of RT is possible on FNA. In the current study, 12 of 13 cases were diagnosed by FNA with a combination of clinical information, immunocytochemistry, and molecular analysis. Cancer (Cancer Cytopathol) 2010;. © 2010 American Cancer Society (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4146585 Mon, 25 Oct 2010 00:00:00 +0100 4146585 http://www.medworm.com/index.php?rid=4092324&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20120 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4092324 Sun, 24 Oct 2010 07:12:34 +0100 4092324 http://www.medworm.com/index.php?rid=4063292&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20107 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4063292 Thu, 14 Oct 2010 04:22:54 +0100 4063292 http://www.medworm.com/index.php?rid=4063291&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20116 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4063291 Thu, 14 Oct 2010 04:22:54 +0100 4063291 http://www.medworm.com/index.php?rid=4063290&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20115 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4063290 Thu, 14 Oct 2010 04:22:54 +0100 4063290 http://www.medworm.com/index.php?rid=4063288&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20111 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4063288 Thu, 14 Oct 2010 04:22:51 +0100 4063288 http://www.medworm.com/index.php?rid=4058070&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20117 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4058070 Tue, 12 Oct 2010 20:58:46 +0100 4058070 http://www.medworm.com/index.php?rid=4038575&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20118 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4038575 Tue, 24 Aug 2010 23:00:00 +0100 4038575 http://www.medworm.com/index.php?rid=3990456&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20098 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3990456 Tue, 24 Aug 2010 23:00:00 +0100 3990456 http://www.medworm.com/index.php?rid=3948956&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20108 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3948956 Tue, 24 Aug 2010 23:00:00 +0100 3948956 http://www.medworm.com/index.php?rid=3918097&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20096 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3918097 Tue, 24 Aug 2010 23:00:00 +0100 3918097 http://www.medworm.com/index.php?rid=3897851&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20103 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3897851 Tue, 24 Aug 2010 23:00:00 +0100 3897851 http://www.medworm.com/index.php?rid=3870787&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20101 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3870787 Tue, 17 Aug 2010 07:15:37 +0100 3870787 http://www.medworm.com/index.php?rid=3870786&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20085 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3870786 Tue, 17 Aug 2010 07:15:37 +0100 3870786 http://www.medworm.com/index.php?rid=3870785&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20100 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3870785 Tue, 17 Aug 2010 07:15:36 +0100 3870785 http://www.medworm.com/index.php?rid=3838671&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20075 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838671 Thu, 24 Jun 2010 23:00:00 +0100 3838671 http://www.medworm.com/index.php?rid=3838670&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20046 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838670 Thu, 24 Jun 2010 23:00:00 +0100 3838670 http://www.medworm.com/index.php?rid=3838669&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20078 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838669 Thu, 24 Jun 2010 23:00:00 +0100 3838669 http://www.medworm.com/index.php?rid=3838668&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20077 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838668 Thu, 24 Jun 2010 23:00:00 +0100 3838668 http://www.medworm.com/index.php?rid=3838667&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20073 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838667 Thu, 24 Jun 2010 23:00:00 +0100 3838667 http://www.medworm.com/index.php?rid=3838666&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20074 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838666 Thu, 24 Jun 2010 23:00:00 +0100 3838666 http://www.medworm.com/index.php?rid=3838664&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20086 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838664 Thu, 24 Jun 2010 23:00:00 +0100 3838664 http://www.medworm.com/index.php?rid=3838663&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20084 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838663 Thu, 24 Jun 2010 23:00:00 +0100 3838663 http://www.medworm.com/index.php?rid=3838648&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20099 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838648 Thu, 24 Jun 2010 23:00:00 +0100 3838648 http://www.medworm.com/index.php?rid=4063289&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20112 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=4063289 Fri, 01 Jan 2010 00:00:00 +0100 4063289 http://www.medworm.com/index.php?rid=3990457&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20110 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3990457 Fri, 01 Jan 2010 00:00:00 +0100 3990457 http://www.medworm.com/index.php?rid=3948958&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20114 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3948958 Fri, 01 Jan 2010 00:00:00 +0100 3948958 http://www.medworm.com/index.php?rid=3948957&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20113 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3948957 Fri, 01 Jan 2010 00:00:00 +0100 3948957 http://www.medworm.com/index.php?rid=3918099&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20105 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3918099 Fri, 01 Jan 2010 00:00:00 +0100 3918099 http://www.medworm.com/index.php?rid=3918098&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20102 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3918098 Fri, 01 Jan 2010 00:00:00 +0100 3918098 http://www.medworm.com/index.php?rid=3897853&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20106 The utility of fine‐needle aspiration biopsy in patients with non‐Hodgkin lymphoma remains unsettled. Competing philosophies continue to debate its proper role in this cancer. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3897853 Fri, 01 Jan 2010 00:00:00 +0100 3897853 http://www.medworm.com/index.php?rid=3897852&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20109 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3897852 Fri, 01 Jan 2010 00:00:00 +0100 3897852 http://www.medworm.com/index.php?rid=3838662&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20081 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838662 Fri, 01 Jan 2010 00:00:00 +0100 3838662 http://www.medworm.com/index.php?rid=3838661&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20080 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838661 Fri, 01 Jan 2010 00:00:00 +0100 3838661 http://www.medworm.com/index.php?rid=3838660&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20083 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838660 Fri, 01 Jan 2010 00:00:00 +0100 3838660 http://www.medworm.com/index.php?rid=3838659&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20089 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838659 Fri, 01 Jan 2010 00:00:00 +0100 3838659 http://www.medworm.com/index.php?rid=3838658&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20093 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838658 Fri, 01 Jan 2010 00:00:00 +0100 3838658 http://www.medworm.com/index.php?rid=3838657&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20091 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838657 Fri, 01 Jan 2010 00:00:00 +0100 3838657 http://www.medworm.com/index.php?rid=3838656&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20092 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838656 Fri, 01 Jan 2010 00:00:00 +0100 3838656 http://www.medworm.com/index.php?rid=3838655&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20082 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838655 Fri, 01 Jan 2010 00:00:00 +0100 3838655 http://www.medworm.com/index.php?rid=3838654&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20087 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838654 Fri, 01 Jan 2010 00:00:00 +0100 3838654 http://www.medworm.com/index.php?rid=3838653&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20088 (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838653 Fri, 01 Jan 2010 00:00:00 +0100 3838653 http://www.medworm.com/index.php?rid=3838652&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20090 The Bethesda System for Reporting Thyroid Cytopathology has been gaining acceptance in the United States. Modifications will be made on the basis of an evolving understanding of thyroid disease and additional published evidence. Dr. Renshaw's studies are welcome additions to the growing literature on thyroid fine‐needle aspiration. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838652 Fri, 01 Jan 2010 00:00:00 +0100 3838652 http://www.medworm.com/index.php?rid=3838651&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20095 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838651 Fri, 01 Jan 2010 00:00:00 +0100 3838651 http://www.medworm.com/index.php?rid=3838650&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20097 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838650 Fri, 01 Jan 2010 00:00:00 +0100 3838650 http://www.medworm.com/index.php?rid=3838649&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncy.20094 Abstract (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=3838649 Fri, 01 Jan 2010 00:00:00 +0100 3838649 http://www.medworm.com/index.php?rid=2086582&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.24143 No abstract. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=2086582 Thu, 08 Jan 2009 05:00:00 +0100 2086582 http://www.medworm.com/index.php?rid=2086583&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.24078 No abstract. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=2086583 Tue, 06 Jan 2009 05:00:00 +0100 2086583 http://www.medworm.com/index.php?rid=2493865&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.24099 No abstract. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=2493865 Fri, 19 Dec 2008 00:00:00 +0100 2493865 http://www.medworm.com/index.php?rid=2039292&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23948 In this study, the authors evaluated the applicability of flow-cytometric immunophenotyping (FCI) and compared it with immunocytochemistry (ICC) for the accurate categorization of MSRCTs.In total, 37 consecutive MSRCTs that had been diagnosed with FNA cytology were analyzed by ICC and FCI using a panel of antibodies against desmin, vimentin, CD99/major histocompatibility class I-related antigen 2, neuron-specific enolase, and pancytokeratin. The final diagnoses included Ewing sarcoma (n = 17), rhabdomyosarcoma (n = 6; 4 embryonal and 2 alveolar subtypes), neuroblastoma (n = 10), desmoplastic small round cell tumor (n = 2), and retinoblastoma (n = 2).Accurate categorization was possible in 67.5% of cases by ICC and in 64.8% of cases by FCI. Concordant immunophenotyping results with either t... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=2039292 Wed, 17 Dec 2008 05:00:00 +0100 2039292 http://www.medworm.com/index.php?rid=1968114&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23951 Although liquid-based cervicovaginal cytology has high sensitivity for detecting dysplastic/malignant lesions, many pitfalls exist. Cell blocks can be prepared from residual liquid-based cervicovaginal material and used for immunohistochemistry. The aim of this study was to evaluate a new marker, ProEx C, on cell blocks and its ability to distinguish dysplastic/malignant lesions from morphologically abnormal but benign cells. The results of this study were compared with previously reported results for p16 and Ki-67 on the same material.ProEx C is a cocktail of monoclonal antibodies against proteins associated with aberrant S phase cell cycle induction (topoisomerase IIA, minichromosome maintenance protein 2). ThinPrep (CytycCorp., Boxborough, Mass) cervicovaginal specimens from 79 patients... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1968114 Wed, 19 Nov 2008 05:00:00 +0100 1968114 http://www.medworm.com/index.php?rid=1951245&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23981 The objectives of the current study were to examine GST-pi and P-gp expression in cytologic specimens from patients with unresectable NSCLC and to determine the association of that expression with response to chemotherapy and survival.Patients with unresectable, cytologically diagnosed NSCLC were eligible for the study. Diagnosis was made by fiberoptic bronchoscopy, and staging was done according to international standards. All patients received sequential chemoradiotherapy and were re-evaluated for treatment response. GST-pi and P-gp expression levels were evaluated by immunocytochemistry and immunohistochemistry of bronchial brushing/washing and bronchial tissue biopsy, respectively. Survival was defined as the time between diagnosis and death or last follow-up at 24 months.Thirty-nine p... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1951245 Wed, 12 Nov 2008 05:00:00 +0100 1951245 http://www.medworm.com/index.php?rid=1938229&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23982 In this report, the authors describe a complementary approach to thyroid biopsy that has worked well.All thyroid FNA and CB/CP that were performed in the IR Department during the year 2005 were reviewed. Follow-up histology and records of all procedural complications were retrieved.Seven hundred thirteen thyroid biopsies qualified, 225 biopsies (31%) had FNA with CB/CP (85% had only CP for evaluation), and 488 biopsies (69%) had only FNA. The final unsatisfactory rate in IR for FNA was 8.7%; this was reduced to 3.4% with the use of CB/CP. The addition of CB also helped to obtain a more definitive diagnosis in suboptimal FNA specimens. Cytologic-histologic correlation was comparable for FNA only cases and FNA/CB cases. There were no significant procedural complications in CB cases.FNA in co... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1938229 Fri, 07 Nov 2008 05:00:00 +0100 1938229 http://www.medworm.com/index.php?rid=1938230&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23984 The objective of this study was to compare findings after a cytologic report of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion (LSIL-H) with findings after a report of low-grade squamous intraepithelial lesion (LSIL).A review of patient records revealed that 312 women had cytologic findings of LSIL-H, and 324 consecutive women in a comparison group had cytologic findings of LSIL during 2005. Findings over 6 months after diagnosis were retrieved and analyzed using chi-square tests, Fisher exact tests, and independent group t tests.Histology was available for 194 of 312 women (64%) with LSIL-H and for 184 of 324 women (57%) with LSIL. Of these, 47 of 194 women (24%) with LSIL-H had grade 2 cervical intraepithelial neoplasia or greater (CI... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1938230 Wed, 05 Nov 2008 05:00:00 +0100 1938230 http://www.medworm.com/index.php?rid=1929800&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23983 The objective of the current study was to evaluate and describe the cytologic features of extragonadal germ cell tumors (GCTs), both primary and metastasis from gonadal sites, in fine-needle aspiration cytology.Aspirates from 88 extragonadal GCTs were retrieved with their clinical features and cytologic smears. The smears were assessed for cellularity, cell patterns, and cytologic features, which were summarized. Histopathology was available in 47 cases, and cytohistologic correlation was done in all such cases.Of 88 cases, 57 with adequate cytologic material were analyzed. Each type of GCT, except for embryonal carcinoma, had characteristic morphologic features. Seminomas had dyscohesive tumor cells with well defined, vacuolated cytoplasm; prominent nucleolus; and background lymphocytes. ... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1929800 Tue, 04 Nov 2008 05:00:00 +0100 1929800 http://www.medworm.com/index.php?rid=1929801&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23949 Previous studies have confirmed the low predictive value of a diagnosis of atypical squamous cells, cannot exclude a high-grade squamous intraepithelial lesion (ASC-H) in a Papanicolaou (Pap) smear for subsequent high-grade dysplasia in the postmenopausal age group. It appears plausible that the decrease in estrogen inherent in the postmenopausal state likely produces reactive cytologic atypia, which is misinterpreted as ASC-H. The change in hormone levels observed in pregnant patients, postpartum patients, and contraceptive users, as a corollary, potentially could create a similar diagnostic dilemma. In the current study, the impact of age and altered hormone status on the frequency of ASC-H was assessed to answer the following questions: Is the low predictive value of ASC-H in postmenopa... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1929801 Mon, 03 Nov 2008 05:00:00 +0100 1929801 http://www.medworm.com/index.php?rid=1920727&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23947 The objective of the current study was to compare the results of liquid-based cytology and HPV DNA testing through polymerase chain reaction in 99 penile samples collected from men presenting with condyloma acuminate or male partners of HPV-infected women who had attended a public health service in the city of Belo Horizonte, Minas Gerais, Brazil. Classic and nonclassic cytomorphologic signs were adopted to evaluate the presence of HPV infections in penile smears.HPV DNA was detected in 93 (93.9%) of the 99 samples analyzed. Koilocytosis was detected in 1 smear and nonclassic signs were detected in 23 smears, 22 of which were found to be positive for HPV DNA.The cytopathologic detection of HPV infection in penile samples collected for liquid-based cytology is low, even when cytologic noncl... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1920727 Thu, 30 Oct 2008 04:00:00 +0100 1920727 http://www.medworm.com/index.php?rid=1911114&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23950 No abstract. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1911114 Tue, 28 Oct 2008 04:00:00 +0100 1911114 http://www.medworm.com/index.php?rid=1802350&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23798 Apart from several subjective criteria, ASCUS and LSIL are defined by nuclear enlargement of 2.5× to 3× and [ge]3× the area of a normal intermediate squamous cell nucleus, respectively. The aim of this study was to assess the ability of observers with various degrees of experience to estimate nuclear area ratios.Forty-five participants (5 anatomic pathologists, 5 cytopathologists, 2 cytopathology fellows, 16 pathology residents, 8 cytotechnologists, 6 medical students, and 3 cytopreparatory staff members) judged the area ratios of pairs of squamous cell nuclei imaged at ×100 objective magnification. For Test 1 (T1), participants chose between 5 preset area ratios (1.0× to 1.4×, 1.5× to 1.9×, 2.0× to 2.4×, 2.5× to 2.9×, 3.0× to 3.4×) for 15 pairs of cells with ratios falling i... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1802350 Thu, 18 Sep 2008 04:00:00 +0100 1802350 http://www.medworm.com/index.php?rid=1802352&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23793 The most common presenting site of extracutaneous disease in mycosis fungoides and Sezary syndrome is the peripheral lymph node. Although fine-needle aspiration biopsy has been shown to be a valuable diagnostic technique in evaluating lymphadenopathy, its utility in patients with cutaneous T-cell lymphoma has not been extensively studied. With fine-needle aspiration biopsy, material can be collected for ancillary diagnostic studies and for morphologic evaluation.The authors report a series of 11 fine-needle aspiration biopsy specimens from 10 mycosis fungoides and Sezary syndrome patients. Flow cytometric immunophenotyping and T-cell receptor gamma chain polymerase chain reaction were performed on fine-needle aspiration biopsy material and correlated with cytologic findings.Seven of 10 pat... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1802352 Wed, 17 Sep 2008 04:00:00 +0100 1802352 http://www.medworm.com/index.php?rid=1802351&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23795 No abstract. (Source: Cancer Cytopathology) Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1802351 Wed, 17 Sep 2008 04:00:00 +0100 1802351 http://www.medworm.com/index.php?rid=1797496&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23797 Tissue microarray allows rapid and efficient evaluation of gene expression at the protein level and of immunochemical markers. To our knowledge, there has been no report of constructing cytology microarray using effusion cell blocks and testing its utility in immunochemical marker validation.A total of 23 malignant effusions (primary tumor of breast [5], GI tract [5], lung [5] and ovary [8]) were used to construct a cytology microarray so that 3 cores of 0.6 mm in diameter were taken from the original cell blocks. Antibodies including AE1/AE3, EMA, and Ki-67 were applied to all cases, and CK7, CK20, TTF-1, WT-1, ER, and PR antibodies were used for selected cases. The cellularity, composition of cells, the staining pattern, and the intensity of each antibody were compared between correspond... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1797496 Wed, 17 Sep 2008 04:00:00 +0100 1797496 http://www.medworm.com/index.php?rid=1700057&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23799 In this study, the CSF findings in patients with ependymal neoplasms are summarized and the cytomorphologic features of ependymoma, including its variants, are illustrated.A search of the pathology databases of 2 medical centers was performed to identify all patients with a histologic diagnosis of ependymoma in whom CSF samples were examined. Slides from CSF samples originally reported as atypical, suspicious, or positive were reviewed and the cytomorphologic features assessed. Follow-up included a review of the medical records and histologic correlation.In all, 177 patients with a diagnosis of ependymoma were identified. Of these, 48 had a total of 94 cytologic preparations of CSF. Positive, suspicious, atypical, negative, and nondiagnostic results were noted in 6.4%, 5.3%, 4.3%, 79.7%, a... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1700057 Wed, 13 Aug 2008 04:00:00 +0100 1700057 http://www.medworm.com/index.php?rid=1682057&cid=s_33596_32_f&fid=33596&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fcncr.23796 This study evaluated the use of a multicolor fluorescence in situ hybridization (FISH) probe panel specifically designed for chronic lymphocytic leukemia (CLL)/SLL and assessed the association between FISH findings and cytologic diagnosis, proliferation index, and risk of death.FNA specimens from 50 patients (32 men and 18 women; mean age, 57 years [range, 36-77 years]) with histologically confirmed CLL and/or SLL were evaluated in this study for chromosomal abnormalities of 11q22 (ATM), 12, 13q14.3, 13q34.3 (LAMP1), and 17p13.1 (p53) by using a multiprobe FISH kit. One of the 50 cases was excluded because of an insufficient number of cells for FISH analysis. The FISH findings were compared with the cytologic diagnoses (26 SLLs, 12 SLLaccs, and 11 tLCLs), Ki-67 immunostaining, and risk of ... Cancer Cytopathology journals http://www.medworm.com/rss/comments.php?id=1682057 Wed, 06 Aug 2008 04:00:00 +0100 1682057