MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Central European Journal of Medicine' source. Sun, 21 Mar 2010 15:20:59 +0100 http://www.medworm.com/index.php?rid=3386436&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc10vv27n62232557%2F Abstract  Pressure ulcers and falls are frequent adverse events with negative impacts for hospital patients. Guidelines recommend risk assessment as the first step in prevention. Care dependency correlates with falls and pressure ulcers and the Care Dependency Scale showed a diagnostic validity comparable to that of specific risk assessment tools. The aim of this study was to establish a simple and valid screening index for the risk of falls and pressure ulcers in hospitals by using the Care Dependency Scale and to evaluate this index within two validation samples from different countries. Quantitative, cross-sectional data from two German surveys and one Dutch survey were analysed. A total of 305 Dutch and German hospitals with 21,880 patients took part. The diagnostic val... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3386436 Thu, 18 Mar 2010 15:39:18 +0100 3386436 http://www.medworm.com/index.php?rid=3386435&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv1g631j140401102%2F Abstract  Anal human papillomavirus (HPV) infection commonly affects men who have sex with men (MSM) and is associated with the development of anal cancer, with the highest prevalence in MSM who are positive for human immunodeficiency virus (HIV). The purpose of this study was to determine the prevalence of anal HPV infection and genotype distribution in Slovenian MSM and its correlation with behavioral patterns in order to predict the possible impact of quadrivalent HPV vaccine in this population. To our knowledge, this is the first study of prevalence and genotype distribution of anal HPV infection in MSM from any of the Eastern European countries. The study included 136 MSM who visited two outpatient offices from January 2007 through December 2008. All participants were ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3386435 Thu, 18 Mar 2010 15:39:18 +0100 3386435 http://www.medworm.com/index.php?rid=3356307&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb38t21t557608j16%2F Abstract  The aim of this study is to determine the difference in efficiency of direct immunoenzyme-linked assay (EIA) and conventional microscopy (CM) plus conventional concentration technique (CCT) using comparative analysis in the diagnosis of symptomatic and asymptomatic lambliosis when only one stool sample is to be tested. The study enrolled 577 examinees: 208 patients and 369 asymptomatic examinees. Lambliosis was diagnosed using CM plus CCT (three stool samples) and direct EIA (the first sample). All statistical parameters of the EIA method were 100% in the patients with symptoms of infection. In addition to that, in the group of asymptomatic carriers of Giardia lamblia (G. lamblia) some very high values of these parameters were recorded too, with sensitivity and neg... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3356307 Wed, 10 Mar 2010 15:29:14 +0100 3356307 http://www.medworm.com/index.php?rid=3313147&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy3mp04gw66821750%2F Abstract  Neopterin is a useful indicator of the activation state of the cellular immune system, and an elevated level predicts prognosis in different types of tumors. The aim of this study was to evaluate serum neopterin levels if it is viable predictor for prognosis in breast carcinoma patients. Serum neopterin was investigated in 56 breast carcinoma patients, 16 patients with benign breast lesions and 16 healthy women as controls. Neopterin was measured by ELISA (Enzyme-linked immunosorbent assay). The clinicopathological parameters were determined by reviewing both medical charts and pathological records. All patients had been followed-up until September 2009 or death.The mean serum neopterin concentrations were 8.5 ± 5.2 nmol/L in patients with breast carcinoma, 6.5±3... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3313147 Thu, 25 Feb 2010 08:01:27 +0100 3313147 http://www.medworm.com/index.php?rid=3313148&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx0127265r5494769%2F Abstract  The operative deliveries can expose the fetus to acute and systemic hypoxia along with an increase in perinatal morbidity. The aim of this study was to reveal any relationship between delivery type and Chitotriosidase and Troponin T levels in cord blood. Ninety babies born in Ankara Etlik Maternity and Women’s Health Teaching Hospital were involved in the study. The babies were divided into three groups; Group 1: Normal vaginal; Group 2: Caesarean section; Group 3: Forceps application. Cord blood samples were drawn from umbilical arteries of the babies soon after the birth. Chitotriosidase enzyme activities in group 3 (141 nmol/ml/h (0–246)) were found higher than groups 1 (100 nmol/ml/h (0–208)) and 2 (91 nmol/ml/h (0–202)) (p<0.01 and p<0.03 respec... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3313148 Thu, 25 Feb 2010 08:01:26 +0100 3313148 http://www.medworm.com/index.php?rid=3313149&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F672437w2420771g8%2F Abstract  Cardiac osteosarcoma metastasis is extremely rare and is documented in several case reports in the literature. The behaviour of osteosarcoma metastases is similar to the primary tumour. Thoracic non-enhanced computed tomography (CT) examination is beneficial in the detection of calcific cardiac metastases. In this case report, we describe a 29-year-old woman with cardiac osteosarcoma metastasis after 7 years of follow-up, compare the demographic features with previous cases and discuss the imaging findings. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-010-0018-5Authors Hilal Sahin, Ege University Faculty of Medicine, Department of Radiology Izmir 35100 TurkeyNaim Ceylan, Ege University Faculty of Medicine, Department of Radiology Izmir 3... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3313149 Thu, 25 Feb 2010 08:01:25 +0100 3313149 http://www.medworm.com/index.php?rid=3277735&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2335p1u106468685%2F Abstract  Topiramate is an effective drug for the prevention of migraine headaches. On occasion, topiramate can be associated with a dose-related anorgasmia. Presented here is an adult case of reversible anorgasmia induced by and possibly attributable to topiramate therapy. Physicians need to be aware of the potential for topiramate to dose related reversible anorgasmia, and should inquire about sexual symptoms of patients. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-010-0008-7Authors Serkan Kilbas, Rize University School of Medicine Department of Neurology 53100 Rize TurkeyAynur Kilbas, Rize University School of Medicine Department of Biochemistry 53100 Rize TurkeyErtugrul Uzar, Fatih University School of Medicine Department of Neurology 06510 Anka... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3277735 Mon, 15 Feb 2010 06:39:59 +0100 3277735 http://www.medworm.com/index.php?rid=3277738&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F97h84860803112l7%2F This study revealed that high levels of fascin and EMMPRIN expression may indicate the importance of their roles in the progression of non-small cell lung carcinoma and they could be used as prognostic marker for these tumors. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-010-0013-xAuthors Mehmet Kefeli, Ondokuz Mayis University 55139 Samsun TurkeyAysen Taslak Sengul, Ondokuz Mayis University 55139 Samsun TurkeyLevent Yildiz, Ondokuz Mayis University 55139 Samsun TurkeySancar Baris, Ondokuz Mayis University 55139 Samsun TurkeyAhmet Basoglu, Ondokuz Mayis University 55139 Samsun TurkeyBedri Kandemir, Ondokuz Mayis University 55139 Samsun Turkey Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central Europ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3277738 Mon, 15 Feb 2010 06:39:58 +0100 3277738 http://www.medworm.com/index.php?rid=3277737&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9320h3hl27p83246%2F In conclusion, elevated plasma fibrinogen and constantly decreasing antithrombin were shown to be linked to the development of severe sepsis. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-010-0012-yAuthors Irma Matinlauri, University of Kuopio Department of Clinical Chemistry P.B. 1700 70211 Kuopio FinlandAuni Juutilainen, Kuopio University Hospital Department of Medicine P.B. 1777 70211 Kuopio FinlandSari Hämäläinen, Kuopio University Hospital Department of Medicine P.B. 1777 70211 Kuopio FinlandIrma Koivula, Kuopio University Hospital Department of Medicine P.B. 1777 70211 Kuopio FinlandTaru Kuittinen, Kuopio University Hospital Department of Medicine P.B. 1777 70211 Kuopio FinlandEsa Jantunen, Kuopio University Hospital Department of Medicine P.B. 1777... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3277737 Mon, 15 Feb 2010 06:39:58 +0100 3277737 http://www.medworm.com/index.php?rid=3277736&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr8l4685l3u055x01%2F In conclusion, the carotid-femoral PWV is elevated in peritoneal dialysis patients. Increased PWV in PD patients is associated with age, diabetic status, and longer duration of PD therapy, but not with this type of peritoneal transport. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-010-0014-9Authors Paweł Stróżecki, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz Department of Nephrology, Hypertension and Internal Diseases 85-094 Bydgoszcz PolandRafał Donderski, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz Department of Nephrology, Hypertension and Internal Diseases 85-094 Bydgoszcz PolandMagdalena Grajewska, Nicolaus Copernicus University, Collegium Medicum in Bydgoszcz Department of Nephrology, Hypertension and Interna... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3277736 Mon, 15 Feb 2010 06:39:58 +0100 3277736 http://www.medworm.com/index.php?rid=3277739&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8371866t78m7v620%2F Abstract  Glomus caroticum tumors, usually used as an alternative term for carotid body tumor, are of neuroectodermal origin and a part of the extra adrenal neuroendocrine system pathologies. These abnormalities are the most frequently detected paraganglioma in the localization of the head and neck. In our report, we present a giant tumor mass on the left side which was operated on successfully with a review of our experience retrospectively. Between the dates of June 1995 and October 2009, 47 patients, all of which had a glomus caroticum tumor, underwent to surgery. Tumor presented a wide variety of size and clinical presentations. Content Type Journal ArticleCategory Review ArticleDOI 10.2478/s11536-010-0015-8Authors Sureyya Talay, Erzurum Regional Training and Researc... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3277739 Mon, 15 Feb 2010 06:39:57 +0100 3277739 http://www.medworm.com/index.php?rid=3241568&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff927466502v86116%2F Abstract  The aim of this study was to assess the relationship between lifestyle characteristics and the probability of metabolic syndrome in the Lithuanian middle-aged population of Kaunas city. Study sample was comprised of 1403 individuals aged 35–64 years. Metabolic syndrome was defined by International Diabetes Federation definition. Lifestyle habits were evaluated using frequency questionnaires. The prevalence of metabolic syndrome was identified in 29.7% of men and 35.1% of women. In men only alcohol intake increased the risk of metabolic syndrome: wine intake daily or several times a week increased the risk of metabolic syndrome in men aged 35–49 years by 3.8-fold whereas intake of spirits once a week or more often increased the risk of metabolic syndrome in men... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3241568 Tue, 02 Feb 2010 17:55:16 +0100 3241568 http://www.medworm.com/index.php?rid=3233425&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw5222p024lr07502%2F Abstract  Early detection and treatment of preneoplastic lesions represents an obvious option to reduce morbidity and mortality from lung malignancies. Until now, radiological detection, sputum cytology, and autofluorescence have shown limited effectiveness as screening methods. Novel technologies such as Narrow Band Imaging (NBI) are showing promising results, but new studies are still needed to evaluate their use as screening methods. Together with early detection, adequate methods of lesion treatment, such as argon plasma coagulation, are needed. This case report concerns a 45-year-old man who was referred for bronchoscopy after his annual checkup. Using NBI technology, a preneoplastic lesion was identified, and treated using argon plasma coagulation. Our experience has ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3233425 Mon, 01 Feb 2010 06:47:45 +0100 3233425 http://www.medworm.com/index.php?rid=3233426&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd5666r8t74461282%2F Abstract  Syngeneic transplantation of murine aorta segments with advanced atherosclerotic lesions in defined recipients is a valuable model for regression studies. To date, this model has not been used to study the regression of initial atherosclerotic lesions. The aim of this study was to evaluate a microsurgical technique of syngeneic heterotopic transplantation of the thoracic aorta of young apolipoprotein E-deficient (ApoE-/-) mice to the abdominal aorta of wild-type recipients. Stereological quantification methods were tested in order to assess changes in structure and volume of the aortic wall including the involvement of immune cells in changes of the atherosclerotic lesions. The animals were euthanised one month after surgery and histological analysis including ste... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3233426 Mon, 01 Feb 2010 06:47:44 +0100 3233426 http://www.medworm.com/index.php?rid=3233427&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5k33788685172537%2F Abstract  Genitourinary tuberculosis (GUTB) is an extrapulmonary manifestation of tuberculosis seen in 1.2% of all cases of tuberculosis. The clinical case of a 54-year-old woman diagnosed with GUTB is presented. Cloudy urine, abdominal pain, and microscopic hematuria led us to investigate for Mycobacterium tuberculosis. Although cultures were negative, positive Ehrlich-Ziehl-Neelsen (EZN) staining and a positive polymerase chain reaction (PCR) revealed the diagnosis of M. tuberculosis complex (MTC), which was confirmed by treatment success. It has been shown that PCR is a reliable and rapid method for establishing or supporting the diagnosis of tuberculosis and can be used in a routine diagnostic algorithm when conventional methods fail to identify MTC. Content Type Jour... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3233427 Mon, 01 Feb 2010 06:47:43 +0100 3233427 http://www.medworm.com/index.php?rid=3233429&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl672442122235p66%2F Abstract   De novo translocation interrupting the transcription unit of SATB2 gene has been associated with cleft palate only (CPO). We tested for the presence of the copy number of SATB2 gene in a sample of 92 patients with CPO using a quantitative real-time PCR approach. In one patient (1%, 95% CI = 0.2%–6%), a 19 Mb de novo deletion encompassing the SATB2 gene was detected. These results suggest that SATB2 gene deletions do not play an important role in the etiology of cleft palate. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0141-3Authors Karin Writzl, University Medical Centre Ljubljana Division of Medical Genetics, Department of Obstetrics and Gynecology 1000 Ljubljana SloveniaLuca Lovrečić, University Medical Centre Ljubljana Divi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3233429 Mon, 01 Feb 2010 06:47:42 +0100 3233429 http://www.medworm.com/index.php?rid=3233428&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv8u822013lw781x5%2F Abstract  Combined antifungal therapy has been suggested to enhance the efficacy and reduce the toxicity of antifungal agents. The aim of the study was to investigate the in vitro synergistic activity of caspofungin, voriconazole, and fluconazole with amphotericin B against ten isolates of Candida parapsilosis and Candida albicans strains which were resistant to azoles or amphotericin B. Three different antifungal combinations (amphotericin B [AP] — caspofungin [CS], amphotericin B — fluconazole [FL], and AP — voriconazole [VO]) were evaluated for in vitro synergistic effect by the microdilution checkerboard and E-test methods. For the majority of strains, the combination test showed indifferent activity. Via the E-test method, synergistic activity was seen in 3 strains ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3233428 Mon, 01 Feb 2010 06:47:42 +0100 3233428 http://www.medworm.com/index.php?rid=3224106&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd734x536l7547j63%2F Abstract  It was the aim of this study to assess fluoride retained in saliva after use of fluoride-containing tablet DENTTABS® compared to toothpaste containing amine fluoride. Four subjects (2 normal saliva secretors, 1 slow secretor, and 1 fast secretor) participated in this crossover study comparing DENTTABS® and ELMEX®. After baseline sample collection, calibrated study personnel brushed the subjects’ teeth with the assigned product for 3 minutes. Saliva samples were taken at baseline (T0), immediately after brushing (T1) and then 10 (T2), 25 (T3) and 85 (T4) minutes post-brushing. The amount of saliva collected was measured, and the fluoride content was analysed. All 4 subjects repeated all study cycles 5 times. Statistical analysis was done using the Mann-Whitney... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3224106 Wed, 27 Jan 2010 19:59:09 +0100 3224106 http://www.medworm.com/index.php?rid=3224105&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw62211071261w358%2F This report presents a SJS case due to combined use of lamotrigine and fluoxetine. A 41-year-old man was admitted to our clinic with fever, skin eruptions (especially on the face and trunk) and lesions around the mouth. The patient’s history revealed lamotrigine and fluoxetine use during the previous three weeks for major depression. Dermatological examination revealed a typical clinical picture of SJS; his psychotropic medications were all stopped. While topical and ocular prednisolone (1mg/kg/day) cares were initiated, steroid dosage was reduced within 15 days. The condition of patient rapidly improved through this treatment. Effective management of SJS begins with prompt recognition of the entity, combined with attention to each of the major organs that may be affected, potentia... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3224105 Wed, 27 Jan 2010 19:59:09 +0100 3224105 http://www.medworm.com/index.php?rid=3224108&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc3l53448470g224k%2F Abstract  Wilson’s disease is an autosomal-recessive disorder caused by mutation in the ATP7B gene. Absent or reduced function of ATP7B protein leads to decreased hepatocellular excretion of copper into bile. Subsequent copper accumulation, first in the liver but ultimately in the brain and other tissues, produces different clinical manifestations such as hepatic, neurological, hematological, ophthalmological, and psychiatric problems. Diagnosis is based on clinical suspicion, parameters of copper metabolism, ophthalmic examination (Kayser-Fleischer rings) and a liver biopsy. Genetic studies are of limited use. Early diagnosis and initiation of therapy with chelators and therapeutic plasma exchange therapy are essential for prognosis. Liver transplantation corrects the un... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3224108 Wed, 27 Jan 2010 19:59:06 +0100 3224108 http://www.medworm.com/index.php?rid=3224107&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl3054h81qj7318j1%2F Abstract  Scombroid fish or histamine food poisoning is an illness typically associated with fish consumption, rarely encountered and reported in Europe. Symptoms develop quickly and resemble an allergic reaction. This paper reports three cases of severe scombroid poisoning in previously healthy patients, which presented diffuse macular erythema, hypotension, palpitations, and abnormal electrocardiogram (ECG). All patients required intensive care, with a complete resolution of symptoms and ECG changes within 24 hours. This is the first Romanian report of scombroid poisoning, emphasizing that medical personnel should be aware of this condition, because symptoms and ECG changes often lead to confusion with other diseases. Content Type Journal ArticleCategory Case ReportDOI ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3224107 Wed, 27 Jan 2010 19:59:06 +0100 3224107 http://www.medworm.com/index.php?rid=3224109&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu60008474j5m8014%2F Abstract  Primary aldosteronism (PA) has long been considered a rare disease, but a higher prevalence was suggested recently. The aim of this study was to evaluate the prevalence of PA in a group of Bulgarian hypertensive patients, including patients with adrenal incidentalomas (AI). The aldosterone to renin ratio (ARR)>750 was used as a positive screening test and the Captopril test was performed to confirm the diagnosis. Adrenal CT scan was used to differentiate between the main subtypes of PA-aldosterone-producing adenoma (APA) and idiopathic hyperaldosteronism (IHA). The diagnosis of APA was retrospectively confirmed after surgery. After excluding other forms of endocrine hypertension, except PA, we investigated a total of 472 consecutive hypertensive patients, among... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3224109 Wed, 27 Jan 2010 19:59:05 +0100 3224109 http://www.medworm.com/index.php?rid=3195553&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F44320558xhv73804%2F In conclusion, benign recurrent intrahepatic cholestasis can be a rare cause of carpal tunnel syndrome in childhood. We also advocate treating the underlying disease as an appropriate conservative treatment before surgery. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0142-2Authors Necati Balamtekin, Hacettepe University Faculty of Medicine, Department of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition 06100 Ankara TurkeyNuray Uslu, Hacettepe University Faculty of Medicine, Department of Pediatrics, Section of Gastroenterology, Hepatology and Nutrition 06100 Ankara TurkeyCagri Temucin, Hacettepe University Faculty of Medicine, Department of Neurology 06100 Ankara TurkeyHulya Demir, Hacettepe University Faculty of Medicine, Department of Pedi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3195553 Tue, 19 Jan 2010 17:47:46 +0100 3195553 http://www.medworm.com/index.php?rid=3195554&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk15552m1l4273743%2F We report a case of pancreatic tuberculosis with systemic brucellosis in a 29 year old veterinarian who presented with epigastric pain and loss of appetite. Initial investigations revealed leukocytosis with moderately elevated transaminase, gamma glutamyl transferase, amylase and lipase levels. Imaging studies revealed an anechoic multiloculated cyst in the body and tail of the pancreas. Given the patient’s occupational risk coupled with the presence of a positive Brucella agglutination test (with a titer of 1:320); a diagnosis of pancreatitis secondary to brucellosis was given. In addition to standard pancreatitis therapy of bowel rest with intravenous fluid/electrolyte replacement, anti-brucellosis therapy was also administered. The patient’s initial response to therapy was pos... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3195554 Tue, 19 Jan 2010 17:47:45 +0100 3195554 http://www.medworm.com/index.php?rid=3161335&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr43455038644873q%2F This study describes the in vivo activity of Lactobacillus acidophilus in Giardia lamblia infected BALB/c mice. Experimentally, it was observed that daily administration of lactobacilli 7 days before or in simultaneous inoculation with Giardia trophozoites efficiently reduced G. lamblia infection in mice. More specifically, excretion of Giardia cysts were reduced significantly in probiotic-treated groups, and resolution of infection was observed by day 21 post-inoculation. It was also observed that the lactobacillus count increased tremendously and continuously in faeces of all probiotic-fed mice, and was significantly higher as compared with that in control mice. Histological analysis of microvilli membrane integrity revealed that probiotic administration also protected mice against p... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3161335 Fri, 08 Jan 2010 21:41:45 +0100 3161335 http://www.medworm.com/index.php?rid=3161336&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh0qxw53175065444%2F We describe and discuss two cases of this rare syndrome in a 46-year perimenopausal and a 59-year old postmenopausal woman. Gynecologic, ultrasound examination, and biochemistry testing (β-HCG) confirm the diagnosis of nonexistent clinical and biochemical pregnancy. These examinations have the potential to confirm abdominal tumors, while psychiatric examinations generally reveal the psychic basis of the disease; which should be treated through team approach by both the psychiatrist and gynecologist. Additionally, special reference should be given to long-term psychiatric follow-up and management of the current mental stress and emotional problems by a combination of antipsychotics and psychotherapy, depending on each individual clinical picture. Content Type Journal ArticleCatego... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3161336 Fri, 08 Jan 2010 09:16:00 +0100 3161336 http://www.medworm.com/index.php?rid=3154772&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8m1v6331737453l5%2F Abstract  Morbidity of obesity-related diseases tends to increase due to a rise in the body mass index (BMI). We aimed to investigate how the body composition and biochemical parameters change while BMI increases in adult women were categorized as so: as normal weight, overweight and obese. Our objectives are to study the effects of those changes in the development of metabolic disturbances and to find out which parameters are the most sensitive to predict cardiometabolic risks. Three hundred and twenty two records of adult women (mean age: 38.62±12.71 year) who admitted to our unit concerning about losing or preserving their weights, were analyzed in the study. All patients had undergone anthropometric measurements and body composition analyses as well as some biochemical... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3154772 Tue, 05 Jan 2010 06:50:35 +0100 3154772 http://www.medworm.com/index.php?rid=3154771&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg1v1122821004482%2F Abstract  We aimed to compare the Singh index with bone mineral density (BMD) by dual-energy X-ray absorptiometry (DXA), body mass index (BMI) and femur geometry in the right proximal femur of osteoporotic women, using different statistical tests. Radiographs of each patient were assessed to determine the Singh index by five observers. The observers consisted of a consultant radiologist, physical therapist and anatomists who studied the series of radiographs. They were asked to apply the Singh index by comparing the trabecular bone pattern in the proximal right femur with the reference scale published by Singh et al. [1]. This has a six point scale from grade VI to grade I. We evaluated 47 osteoporotic women in this study. The subjects’ mean age, weigth, and height were 6... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3154771 Tue, 05 Jan 2010 06:50:35 +0100 3154771 http://www.medworm.com/index.php?rid=3154773&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp1484jx729h54675%2F Abstract  The aim of this study is to investigate the in vitro antimicrobial activity of Ankaferd Blood Stopper® against methicillin-resistant Staphylococcus aureus (MRSA), Enterococcus species, Escherichia coli, Pseudomonas species, Acinetobacter species and Klebsiella species of nosocomial origin. Ankaferd inhibited growth in 72.4% to 100% of the bacteria tested, depending on the type of the isolate. As a result, it can be stated that Ankaferd inhibits the in vitro growth of nosocomial bacteria. This is a novel, important finding since severe hospital infections coexist with many hemostatic disorders, and the use of Ankaferd may increase hemostatic potential in such clinical conditions. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0140-4Au... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3154773 Tue, 05 Jan 2010 06:50:32 +0100 3154773 http://www.medworm.com/index.php?rid=3154775&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxq083j2h8w8wv142%2F We report the first case of early postoperative infection after a medial hemiarthroplasty of the knee with a customized ConforMIS iForma™ interpositional device. The infection was treated successfully by revision surgery with implant removal and antibiotic therapy. Despite the additional diagnosis of rheumatoid arthritis that did not affect the treated knee, the preservation of bony and ligamentous structures enabled a successful re-implantation of another iForma™ implant 9 months later with good clinical results at follow-up examination 1 year postoperatively. This is very much in contrast to the extensive and complex revision surgery, with significant bone loss, in patients with infected unicompartmental or total knee arthroplasties. The iForma™ device may be an alternative t... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3154775 Tue, 05 Jan 2010 06:50:31 +0100 3154775 http://www.medworm.com/index.php?rid=3154774&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F754u6xr3x4056051%2F Abstract  One of the most important adverse drug reactions that physicians encounter is the life-threatening prothrombotic syndrome known as heparin-induced thrombocytopenia (HIT). In patients with a history of heparin-induced thrombocytopenia and coronary arterial disease, alternative anticoagulatory regimens are needed during cardiac surgery for prevention of thrombosis. Treatment options for such patients now generally include the use of alternative anticoagulants such as lepirudin, bivalirudin, argatroban or danaparoid. In this article, we present a case where heparin-induced thrombocytopenia was properly performed coronary arterial bypass grafting by using lepirudin. (This sentence is confusing) Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3154774 Tue, 05 Jan 2010 06:50:31 +0100 3154774 http://www.medworm.com/index.php?rid=3127801&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe2348j2h06u54146%2F We report the case of a patient with no clinically significant history of a coagulopathy disorder, cirrhosis, or portal hypertension who presented with duodenal and jejunal varices that resulted in lower gastrointestinal bleeding with superior mesenteric vein thrombosis. Mesenteric angiography revealed superior mesenteric vein thrombosis and varices at the fourth part of the duodenum and the proximal jejunum draining into the main portal vein, but no active bleeding source was recognized. The patient was hemodynamically unstable. Emergency laparotomy was performed and revealed duodenal and jejunal varices, with occlusion of the superior mesenteric vein. Partial resection of the duodenum and jejunum and end-to-end anastomosis were performed. After surgery, the patient was hemodynamica... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3127801 Mon, 28 Dec 2009 07:12:33 +0100 3127801 http://www.medworm.com/index.php?rid=3127802&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm3152734154u785g%2F Abstract  A 45 year-old man, who had undergone kidney transplantation 7 years prior, was admitted to hospital after a motorcycle accident. The patient was conscious, hemodynamically stable, and had suffered open tibia and femur fractures, as well as closed pubic arm fractures. He had gross hematuria and radiologic study revealed a 3.5 cm length laceration on the transplanted kidney. His renal functions and hematuria recovered after intensive care. He required 2 surgeries for the open fractures but his general condition worsened after the surgical interventions. Acinetobacter, Candida albicans and pseudomonas aeruginosa were determined by blood cultures. Immunosupressive drugs (cyclosporine, prednisolone and azathioprine) were stopped. Despite intensive care, the patient died... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3127802 Mon, 28 Dec 2009 07:12:31 +0100 3127802 http://www.medworm.com/index.php?rid=3106051&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff051m56335687k73%2F Abstract  The etiology of Dupuytren’s disease is controversial and thus the disease can only be treated when it presents with symptoms to warrant intervention. Surgical treatment is the method of choice to preserve hand dexterity and function. It is advisable to perform surgery at an early stage of disease progression, but various surgical techniques have been advocated. A partial fasciectomy is recommend by many authors, whereas a total aponeurectomy, where all palmar tissue is removed, might reduce the risk of recurrent disease due to the widespread removal of aponeurosis. The total aponeurectomy is performed less frequently due to the potential complications of this technique. In order to achieve an objective comparison of both surgical options we performed a literatur... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3106051 Thu, 17 Dec 2009 07:07:02 +0100 3106051 http://www.medworm.com/index.php?rid=3106054&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6611183167590347%2F Abstract  Direct current cardioversion, which produces electrical energy, is highly effective for the termination of cardiac arrhythmia and sometimes is indicated in patients with coronary artery stents due to arrhythmias. Only a few reports have been published describing the potential adverse interactions between foreign bodies and electrical cardioversion. The aim of this animal study was to investigate the acute effect of repeated external defibrillation on coronary artery tissue and adjacent myocardium at the implantation site of coronary stents. Custom-made stainless steel stents were implanted in the coronary arteries of 7 dogs. Rapid ventricular pacing was performed to induce ventricular fibrillation. Defibrillation was achieved [5 J/kg; n=2 and 8 J/kg; n=3]. In 2 an... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3106054 Thu, 17 Dec 2009 07:07:00 +0100 3106054 http://www.medworm.com/index.php?rid=3106053&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F657npj530221h63j%2F In conclusion, incision and drainage should be avoided because it is of limited value. Surgical removal of the involved tissue should be the first treatment of choice. Depending on the defect following excision, local flaps should be preferred over the grafts for recurrence prevention. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0126-2Authors Birol Civelek, Diskapi Y. Beyazit Training and Research Hospital Department of Plastic and Reconstructive Surgery 06100 Ankara TurkeyKadir Aksoy, Diskapi Y. Beyazit Training and Research Hospital Department of Plastic and Reconstructive Surgery 06100 Ankara TurkeyEsra Bilgen, Diskapi Y. Beyazit Training and Research Hospital Department of Plastic and Reconstructive Surgery 06100 Ankara TurkeyIbrahim İnal, Diska... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3106053 Thu, 17 Dec 2009 07:07:00 +0100 3106053 http://www.medworm.com/index.php?rid=3106052&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F67580g7996201451%2F Abstract  Signal averaged electrocardiogram (SAECG) is considered an important noninvasive indicator identifying patients at risk for ventricular arrhythmias. The aim of this study was to improve noninvasive prediction of CAD by integrating SAECG with the result of exercise tests in diabetic patients. Diabetic patients with stable angina pectoris underwent exercise testing and SAECG. Then a diagnostic score was derived that combined results of exercise testing and SAECG. A diagnostic score (0 to 2 points) was calculated by assigning 1 point for a positive exercise test result and 1 point for a positive SAECG. One hundred and seventy patients were included in the study. In patients with a score of 0, the likelihood of CAD is 18% whereas the likelihood of CAD is 95% in patien... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3106052 Thu, 17 Dec 2009 07:07:00 +0100 3106052 http://www.medworm.com/index.php?rid=3086783&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnn4660r6507j78m0%2F Abstract  To analyze the retinal toxicity of bevacizumab at various doses both in vitrectomized and non-vitrectomized rabbit models. Twenty- eight rabbits were included in the study. Twenty- four rabbits were assigned to six groups, with 4 of the rabbits in the control group. The animals in Groups 1, 2 and 3 received bevacizumab at a dose of 0.3 mg, 0.5 mg and 1.5 mg /eye, respectively. The rabbits in Groups 4, 5 and 6 received intravitreal bevacizumab of 0.3 mg, 0.5 mg and 1.5mg/eye, respectively, after gas compression vitrectomy. Two weeks after the procedure, the rabbits were euthanized. Retina tissue samples were then obtained and examined with both light and electron microscopes. In Groups 1, 2 and 3 after bevacizumab injection, toxic degeneration in the photoreceptor ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3086783 Thu, 10 Dec 2009 15:23:09 +0100 3086783 http://www.medworm.com/index.php?rid=3086782&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp684738488t3065r%2F In conclusion, this case is interesting with respect to its clinical picture of acute abdomen due to ileal perforation. The possibility of a germ cell tumor should always be kept in mind in male patients with acute abdomen. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0128-0Authors Ali İlker Filiz, GATA Haydarpaşa Training Hospital Department of General Surgery 34668 Istanbul Turkeyİlker Sücüllü, GATA Haydarpaşa Training Hospital Department of General Surgery 34668 Istanbul TurkeyYavuz Kurt, GATA Haydarpaşa Training Hospital Department of General Surgery 34668 Istanbul TurkeyOğuz Okul, GATA Haydarpaşa Training Hospital Department of General Surgery 34668 Istanbul TurkeyZafer Küçükodaci, GATA Haydarpaşa Training Hospital Department of Pathology... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3086782 Thu, 10 Dec 2009 15:23:09 +0100 3086782 http://www.medworm.com/index.php?rid=3080813&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpq81u662346214l3%2F Abstract  The A3243G mutation in the mitochondrial tRNALeu (UUR) gene is one of the most common causes of mitochondrial DNA related disorders. Originally it was described in MELAS syndrome (Mitochondrial Encephalomyopathy, Lactic acidosis, Stroke-like episodes), later it had been found to be associated with various phenotypes. In our study the mutation frequency of the A3243G mtDNA mutation was investigated in patients with maternal sensoneural hearing loss, stroke-like episodes, ataxia and myopathy with undetermined etiology. We screened 631 Hungarian patients in North-East, South-West and Central Hungary between 1999 and 2008 for this mutation. The mtDNA analysis was performed from blood and/or muscle tissue. The A3243G substitution was present in 6 patients in heteroplasm... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3080813 Tue, 08 Dec 2009 06:48:44 +0100 3080813 http://www.medworm.com/index.php?rid=3080812&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy6w56nx545494q17%2F Abstract  Anti-annexin A5 antibodies are directed against annexin A5 — a phospholipid-binding protein that belongs to the ubiquitous annexin family. These antibodies were first discovered in 1994 by Matsuda et al. in women with recurrent fetal loss or preeclampsia and in patients with systemic lupus erythematosus and positive lupus anticoagulant and/or anticardiolipin antibodies. Since then anti-annexin A5 antibodies have been the focus of research. In addition to their well known prothrombotic and procoagulant activities the authors discuss the involvement of these antibodies in the pathogenesis of antiphospholipid syndrome, recurrent pregnancy loss, systemic lupus erythematosus and other immune and non-immune disorders. Controversial reports are presented and a possible... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3080812 Tue, 08 Dec 2009 06:48:44 +0100 3080812 http://www.medworm.com/index.php?rid=3080814&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw456xw615j586442%2F Abstract  Upper airway resistance syndrome (UARS) is a condition where the apnea-hypopnea index is less than 5 and respiratory-effort related arousal index is more than 10. The clinical presentation of UARS may be the same as obstructive sleep apnea-hypopnea syndrome (OSAS); it sometimes shows up with symptoms hardly suggestive of a sleep-disordered breathing. A 17 year-old male patient had applied to a local psychiatry clinic and complained of chronic fatigue, insomnia, behavioral and academic problems and was treated for anxiety and depression. After a period of unresponsive treatment, he was sent to a sleep center for evaluation of insomnia, which turned out to be a fragmented, unrefreshing sleep episode. Polysomnographical evaluation revealed that he had UARS without OS... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3080814 Mon, 07 Dec 2009 19:36:34 +0100 3080814 http://www.medworm.com/index.php?rid=3077368&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fem7jw77706k71v11%2F Abstract  The aim of the present study was to characterize the pattern of adverse drug reactions (ADRs) reported in a university teaching hospital in south-east Serbia. The study was conducted based on ADRs reported during a six-month period to the ADR reporting unit of the university clinical center. Evaluation of data was done for various parameters, such as patient demographics, drug and reaction characteristics, and outcome of reactions. Assessment was also done for causality, severity and predisposing factors. During the 6-month study period, 44 ADRs were reported, with an overall incidence of 0.33%. No significant difference was seen in the overall incidence of ADRs observed in males and females. Incidence of ADRs among elderly (43.2%) and older (25%) adults was signi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3077368 Mon, 07 Dec 2009 19:36:34 +0100 3077368 http://www.medworm.com/index.php?rid=3077367&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn191t825x08n6766%2F Abstract  Vaccines against rotaviruses are now available in numerous countries, including Turkey. As the vaccines may show various efficiencies against different type specificities and routine vaccination in infants might result in selection and immune escape of wild-type rotavirus strains, strain surveillance has been initiated before and during the vaccine introduction. We aimed to provide corresponding information on local strain prevalence in Anatolia, mid-western Turkey during the introduction of rotavirus vaccines. Stool samples positive for group A rotavirus by commercial enzyme immunoassay were subjected to reverse transcription-polymerase chain reaction based genotyping of the outer capsid antigens, VP7 and VP4, determining G and P type specificities respectively. ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3077367 Mon, 07 Dec 2009 19:36:34 +0100 3077367 http://www.medworm.com/index.php?rid=3064891&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7730424523q1p771%2F Abstract  Cardiovascular complications, including stroke, may be attributed the highest rate of morbidity and mortality in patients with chronic kidney disease (CKD). The aim of our study was to evaluate the prevalence of CKD in patients with symptomatic ischaemic cerebrovascular disease and to establish of whether CKD may define a particular risk pattern of cerebral vessels modifications in this category of patients. The prevalence of CKD was evaluated in 590 consecutive patients with symptomatic ischaemic cerebrovascular disease admitted to a department of neurology. The types of stroke, the vascular territories, the vascular modifications and the haemodynamic changes (resistance index- RI) found by neurosonology (extracranial and transcranial Doppler ultrasound) were ana... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3064891 Sat, 05 Dec 2009 08:59:38 +0100 3064891 http://www.medworm.com/index.php?rid=3080815&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn881327445607043%2F Abstract  Statins are widely used and well tolerated cholesterol-lowering drugs, and when used for therapy purposes reduce morbidity and mortality from coronary heart disease. Simvastatin is one of nine known statins, specific inhibitors of hepatic enzyme 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the rate-limiting step of cholesterol biosynthesis, and is believed to reduce plasma cholesterol levels by decreasing the activity of this enzyme. Statin drugs represent the major improvement in the treatment of hypercholesterolemia that constitutes the main origin of atherosclerosis, leading to coronary heart disease. Although statins are generally safe, minor and severe adverse reactions are well known complications of statin use. Adverse events associated with simvastatin... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3080815 Sat, 05 Dec 2009 08:59:37 +0100 3080815 http://www.medworm.com/index.php?rid=3064892&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe628m8630tlm6w56%2F This study took place in Ankara, Turkey, between 08/2005 and 11/2006. Patients with endoscopic diagnosis of melanosis coli were interviewed for demographical data and use of herbal remedies. A total of 380 colonoscopies were performed during this period. Melanosis coli was diagnosed endoscopically in 12 patients (3.17%), 11 of whom were found to have characteristic pigment-laden macrophages in histopathological examination. Herbal remedies were the main etiological factor in the development of melanosis coli in 10 out of 11 patients. Diffuse involvement was found in 2 patients who had a history of long-term use. In 8 patients, melanosis coli was located in the left side of the colon. Although melanosis coli is a harmless discoloration of colonic mucosa resulting from complementary or... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3064892 Sat, 05 Dec 2009 08:59:37 +0100 3064892 http://www.medworm.com/index.php?rid=3080816&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fwh151m20246r4121%2F Abstract  Bezoars are collections of indigestible materials found in the gastrointestinal tract. Rapunzel syndrome is a rare complication of a gastric trichobezoar in which the mass of hair extends through the pylorus into the small bowel and can even reach the colon. A 12-year-old girl with severe pain and a feeling of “fullness” in the upper abdomen was admitted to Pediatric Surgery. Two days before admission, the patient presented with vague abdominal pain, vomiting with a little blood, and black stool. On physical examination she was pale and listless with patchy alopecia. Abdominal examination showed a mobile, palpable mass in the epigastrium. The initial hematocrit was 7,1%, and the erythrocyte count was 1,12×1012 cells per liter. Abdominal ultrasound and computed... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3080816 Sat, 05 Dec 2009 08:59:36 +0100 3080816 http://www.medworm.com/index.php?rid=3064893&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw1747723jg211071%2F This study was designed to investigate faecal shedding of local isolates of Arcobacter spp. Using real time PCR for confirmation, A. cryaerophilus and A. butzleri were isolated from the stool of healthy chickens. Pathogenicity of the organisms was tested by administering a single oral challenge of 102–109 cfu/ml to 45 healthy adult male albino rats divided equally among 5 groups. Uninfected rats were used as the control group. A. cryaerophilus and A. butzleri produced infection in 100% of the animals. Experimental infection was dose dependent and caused diarrheal illness and faecal shedding was noted up to 5 weeks post infection. The present study demonstrates that rats can act as a reservoir and potential source of Arcobacter infection in humans and animals exposed to this pathogen.... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3064893 Tue, 01 Dec 2009 21:04:50 +0100 3064893 http://www.medworm.com/index.php?rid=3041665&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F883h858qh0388316%2F We describe below a patient with Multiple Endocrine Neoplasia type 1 (MEN type 1) who presented with features of Primary Hyperparathyroidism. However, the actual diagnosis of Parathyroid Carcinoma was delayed until metastases to the lung were discovered. She was also found to have Pituitary Macro adenoma with Silent Acromegaly, with no clinical features whatsoever. She underwent transphenoidal hypophysectomy with postoperative radiotherapy. However, the disease process remained biochemically active necessitating commencement of somatostatin analogues. There is also a tumour at the head of the pancreas which at present is non functional with normal gut hormone profile and normal 24 hour urinary 5-hydroxyl indole acetic acid (5-HIAA) excretion assay. Our case highlights the pitfalls in... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3041665 Wed, 25 Nov 2009 17:02:22 +0100 3041665 http://www.medworm.com/index.php?rid=3041666&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff011558wr32181qk%2F In this study, the in-vivo effects of nociceptin (N/OFQ(1–13)NH2) and its structure analogue [Orn9]N/OFQ(1–13)NH2 were studied on markers of oxidative stress in erythrocytes and liver of rats 4 hours after subplantar administration of carrageenan (CG) (1%, 100 µl) in the right hind paw. A considerable inflammatory oedema of the paw was observed. CG did not change blood haemoglobin content, hematocrit value, glutathione level and antioxidant enzyme activities in the erythrocytes, but there was an increase in lipid peroxidation. In liver, CG-induced imbalance was manifested by an increase in lipid peroxidation and a decrease in glutathione level. Both peptides (20 µg, i.p.), when administered alone, had no effect on all parameters tested. When either [Orn9]N/OFQ(1–13)NH2 or N/O... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3041666 Wed, 25 Nov 2009 17:02:18 +0100 3041666 http://www.medworm.com/index.php?rid=3032217&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F20756703585qmg75%2F In this study, desflurane and sevoflurane resulted in both a significant prolongation of QT and QTc and a significant increase in QT and QTc dispersion when compared with the basal values. In the sevoflurane group, there was no significant increase in postoperative ventricular arrhythmia, compared to that during the preoperative period. However, this increase was significant in the desflurane group (p = 0.009). Sevoflurane and desflurane result in an increase in QT dispersion. Postoperative rhythmic control should carefully be monitored, especially in the desflurane group. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0115-5Authors Muhammet Gozdemir, Atatürk Education and Research Hospital Department of Anesthesiology 06800 Ankara TurkeyEkrem Yeter, ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3032217 Mon, 23 Nov 2009 16:47:14 +0100 3032217 http://www.medworm.com/index.php?rid=3020646&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F96x5331qj170210x%2F Abstract  We investigated the correlation of bone mineral density (BMD) with risk factors and laboratory parameters (e.g., markers of bone turnover, biochemical indicators, and hormonal factors) in males without secondary osteoporosis. A total of 105 males were divided into two groups: Group 1 (n: 52) <60 years, and Group 2 (n:53) ≥ 60 years. The subjects were evaluated for risk factors (European Vertebral Osteoporosis Study (EVOS) and BMD) and for biochemical (i.e., blood calcium, blood phosphorus, urinary calcium/phosphorus, creatinine clearance, osteocalcin, and deoxypyridinoline) and hormonal markers (follicle-stimulating hormone [FSH], luteinizing hormone [LH], free testosterone [fT], and parathyroid [PTH]) of bone mineral metabolism. In Group 1, no significant re... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3020646 Sat, 21 Nov 2009 09:11:29 +0100 3020646 http://www.medworm.com/index.php?rid=3020648&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F08041u3l10736274%2F Abstract  The goal of this research was detection of the drug-resistance level of Mycobacterium tuberculosis infection in the Odesa region of Southwest Ukraine, investigation of the level of mutation in katG and rpoB genes for M. tuberculosis with polymerase chain reaction (PCR), and spread of these mutations in different groups of patients with tuberculosis. An extremely high level of primary and acquired resistance of M. tuberculosis to first-line antituberculosis drugs has been found in the Southwest region of Ukraine. The PCR method has proved to have high sensitivity in the detection of mutations in katG and rpoB genes. The data showed significant spreading of M. tuberculosis strains with mutations in katG and rpoB genes in penitentiaries and an increased level of these mu... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3020648 Sat, 21 Nov 2009 09:11:28 +0100 3020648 http://www.medworm.com/index.php?rid=3020647&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F802mh7104h2lp413%2F Abstract  The H5N1 infection was diagnosed in 12 patients in Turkey and confirmed by the WHO. Of these 12 patients so far, 8 have been published. In this case, we are presenting a case of pneumonia that developed following avian influenza infection in Eskisehir. Our case is one of the 4 patients who were not reported previously. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0110-xAuthors Nurettin Erben, Eski?ehir Osmangazi University, Faculty of Medicine Department of Infectious Diseases and Clinical Microbiology 26040 Eskisehir TurkeyElif Doyuk Kartal, Eski?ehir Osmangazi University, Faculty of Medicine Department of Infectious Diseases and Clinical Microbiology 26040 Eskisehir TurkeySaygin Nayman Alpat, Eski?ehir Osmangazi University, Faculty of ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3020647 Sat, 21 Nov 2009 09:11:28 +0100 3020647 http://www.medworm.com/index.php?rid=3020649&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx699045j75427361%2F Abstract  The prevalence of genetic diseases and congenital malformation in the Israeli Arab community is relatively high, but its distribution is not uniform. The aim of this study was to estimate the frequency of mental retardation disorders in children living in 5 Israeli Arab villages and determine its association with consanguinity. Mental retardation was found to affect 300 children in the screened population, yielding an overall prevalence of 14.5 per 1000. Most of those affected (68%) were the offspring of consanguineous marriages. One village with a high prevalence (4.3%) of neurological hereditary diseases was studied in detail. The prevalence of neurological hereditary diseases and mental retardation associated with consanguinity in these children highlights the ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=3020649 Sat, 21 Nov 2009 09:11:27 +0100 3020649 http://www.medworm.com/index.php?rid=2986908&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj5t7175n4x5p28t8%2F Abstract  The behavior of dispersible tablets containing enteric-coated pellets and oral suspension, both containing roxithromycin, was investigated using dissolution tests in different media. The dissolution test was performed under different pH conditions. For both dosage forms investigated, the test was conducted at pH 1.2, 4.5, and 6.8. Additionally, for dispersible tablets, the test involving increasing pH was performed at pH 1.2 (acid stage) and afterwards at pH 6.8 (buffer stage). The extent of dissolution was measured using high-performance liquid chromatography (HPLC). In all cases tested, roxithromycin underwent rapid degradation at pH 1.2. Dispersible tablets displayed the features of modified release preparations with a non-complete dissolution during the test t... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2986908 Wed, 11 Nov 2009 19:11:38 +0100 2986908 http://www.medworm.com/index.php?rid=2986909&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc6546658g276g668%2F Abstract  To examine the plasma levels of MPO in oligoarthritis and polyarthritis subtypes of JIA in comparison with healthy age-matched controls. Thirty-eight JIA patients (25 girls and 13 boys) aged 9.1–11.8 years and 23 healthy controls (8 girls and 15 boys) participated in the study. Twenty-one patients had oligoarthritis (8 with extended oligoarthritis) and 17 had polyarthritis (among them three were seropositive). The plasma concentration of MPO was measured by the ELISA technique (OxisResearchTM, BIOXYTECH® MPO-EIATM, Portland, OR USA). The mean plasma concentration of MPO in the JIA group was significantly higher than in the control group (76.6±24.8 µg/L versus 62.7±15.6 µg/L; p=0.01). Patients with polyarthritis presented a significantly higher mean plasma M... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2986909 Tue, 10 Nov 2009 18:28:59 +0100 2986909 http://www.medworm.com/index.php?rid=2971552&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0m64w0l807212138%2F We report a 68-year-old woman hospitalized for acute renal failure, vertigo and headache. Magnetic Resonance Imaging (MRI) revealed two and a half and 3cm length cranial lesion, which proved to be plasmacytoma. After complete staging, we retained the diagnosis of immunoglobulin G lambda-type multiple myeloma with intracranial involvement. Cytogenetic analysis of plasma cells detected no change. Currently, she is a regular hemodialysis patient. She is planned to have both systemic therapy with 40mg dexamethasone and cranial radiotherapy. Involvement of the CNS in multiple myeloma is very rare. Diagnosis of multiple myeloma subsequent to initial intrcranial involvement is confined to exceptional cases. Despite aggressive systemic treatments, including autologous stem cell transplantati... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2971552 Fri, 06 Nov 2009 19:40:58 +0100 2971552 http://www.medworm.com/index.php?rid=2971551&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F84366p3p404j0514%2F Abstract  House dust mites live in house dusts and affect the health of humans. Among the many species, Dermatophagoides farinae, D. pteronyssinus, and Euroglyphus maynei have been found to be commonly associated with Ig-E-mediated allergic diseases. As a result, there is increasing effort to develop methods for the diagnosis and treatment of diseases caused by these species. The purpose of the current study was to explore the evolutionary relationships among house dust mites. After adult D. farinae were separated and isolated for total RNA extract, the cDNA coding for Der f 1 and Der f 2 were cloned and sequenced. Then amino acid sequences for group 1 and 2 allergens of two of the most common house dust mites, D. pteronyssinus, E. maynei, were obtained from databases. Interes... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2971551 Fri, 06 Nov 2009 19:40:58 +0100 2971551 http://www.medworm.com/index.php?rid=2968951&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw3188w83r768j288%2F Abstract  The aim of this study was to compare and get a deeper insight into issues of the health and health behavior inequalities among Lithuanian, Polish and Russian school-aged children in national and international contexts. Investigations were carried out in the framework of Health Behavior in School-aged Children (HBSC) study — a WHO collaborative cross-national survey. Five thousand seven hundred and seventy six randomly selected students aged 11, 13, and 15 years of age answered questionnaires in the classroom in 108 schools located in different regions in Lithuania in March–April of 2006. Questions on perceived health and health related behaviors were addressed to the respondent (response rate was 95 %). 5632 questionnaires were selected for further analysis by... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2968951 Wed, 04 Nov 2009 21:39:37 +0100 2968951 http://www.medworm.com/index.php?rid=2936598&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu70k20m073gt6w65%2F Abstract   Staphylococcus aureus is the third most dreaded pathogen posing a severe threat due to its refractory behavior against the current armamentarium of antimicrobial drugs. This is attributed to the evolution of an array of resistance mechanisms responsible for morbidity and mortality globally. Local and international travel has resulted in the movement of drug resistant S. aureus clones from hospitals into communities and further into different geographical areas where they have been responsible for epidemic outbreaks. Thus, there is a dire necessity to refrain further cross movement of these multidrug resistant clones across the globe. The plausible alternative to prevent this situation is by thorough implementation of regulatory aspects of sanitation, formulary us... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2936598 Mon, 26 Oct 2009 06:21:48 +0100 2936598 http://www.medworm.com/index.php?rid=2936597&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F463uu157q5x12232%2F Abstract  The purpose of this study was to evaluate the effects of systemic and intra-arterial application of heparin by measuring tissue levels of inflammatory cytokines. Twenty-one adult male Wistar albino rats were divided into three groups (Group A, B and C). All the rats had undergone ligation of the right femoral artery with 4-0 silk suture to induce limb ischemia. Group A was the control group. In Group B, unfractionated heparin of 1500 U/kg/day was given through the tail vein for 10 days, the same dose was given to distal part of ligated right femoral artery for 10 days in Group C. On the 3rd, 5th, and 10th days, biopsies were taken from rectus femoris muscle on the ischemic extremities. Tumor necrosis factor-α, interleukin-1β, and vascular cell adhesion molecule l... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2936597 Mon, 26 Oct 2009 06:21:48 +0100 2936597 http://www.medworm.com/index.php?rid=2936599&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3m262278762690x7%2F Conclusion: Medical diet programs with iron sources are examined in association with food consumption. Assessment of hematological results suggests that, during pregnancy, each patient should receive a specific dose, rather than a routine dose, of iron and folic acid. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0099-1Authors Funda Elmacioglu, Ondokuz Mayis University Health Services 55139 Samsun TurkeyBulent Surucu, Ondokuz Mayis University Hospital Department of Obstetrics and Gynecology 55139 Samsun TurkeyTayfun Alper, Ondokuz Mayis University Hospital Department of Obstetrics and Gynecology 55139 Samsun TurkeyAliye Ozenoglu, Ondokuz Mayıs University Samsun Health School 55070 Samsun TurkeySerdal Ugurlu, Fatih Sultan Mehmet Training and Research H... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2936599 Mon, 26 Oct 2009 06:21:47 +0100 2936599 http://www.medworm.com/index.php?rid=2936600&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj004873797p70uu8%2F Abstract  The aim of this study was to determine the types nosocomial infections (NIs) and the risk factors for NIs in the central intensive care unit (ICU) of Trakya University Hospital. The patients admitted to the ICU were observed prospectively by the unit-directed active surveillance method based on patient and the laboratory over a 9-month-period. The samples of urine, blood, sputum or tracheal aspirate were taken from the patients on the first and the third days of their hospitalization in ICU; the patients were cultured routinely. Other samples were taken and cultured if there was suspicion of an infection. Infections were considered as ICU-associated if they developed after 48 hours of hospitalization in the unit and 5 days after discharge from the unit if the pati... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2936600 Mon, 26 Oct 2009 06:21:46 +0100 2936600 http://www.medworm.com/index.php?rid=2936602&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2471328161816155%2F Abstract  Gossypiboma (retained surgical sponge) is a pseudotumor within the body that is composed of non-absorbable surgical material with a cotton matrix. Because the symptoms of gossypiboma usually are nonspecific and may appear years after surgery, the diagnosis of gossypiboma may be difficult because the condition may mimic a benign or malignant soft-tissue tumour in the abdomen and pelvis. A 61-year-old woman with a one-year history of left upper-quadrant pain and weight loss was referred to our center. She had undergone peptic ulcer perforation 23 year ago. Physical examination revealed dullness and palpable mass in the left upper abdomen. On examination by computed tomography (CT), a hypodense mass of 12 cm in diameter between the greater curvature of the stomach, p... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2936602 Mon, 26 Oct 2009 06:21:45 +0100 2936602 http://www.medworm.com/index.php?rid=2936601&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa77774j562753503%2F We report a case of pulmonary sclerosing hemangioma with extremely unexpected imaging findings and review the literature. Content Type Journal ArticleDOI 10.2478/s11536-009-0090-xAuthors Ozgur Oztekin, Izmir Education and Research Hospital Radiology Department 35360 Izmir TurkeyRecep Savas, Ege University Faculty of Medicine Department of Radiology 35100 Izmir TurkeyDuygu Gurel, Dokuz Eylül University Faculty of Medicine Department of Pathology 35340 Izmir TurkeyNezih Ozdemir, Dokuz Eylül University Faculty of Medicine Department of Thoracic Surgery 35340 Izmir TurkeyMustafa Akcaoglu, Tepecik Education and Research Hospital Radiology Department 35120 Izmir Turkey Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European J... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2936601 Mon, 26 Oct 2009 06:21:45 +0100 2936601 http://www.medworm.com/index.php?rid=2928965&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj774t2328453348u%2F We examined the age-related changes in the distribution of SP-immunoreactive nerve structures in the distal part of the rat large intestine. Using immunohistochemistry, the presence of SP was studied in fresh tissues from Wistar rats at different ages taken at three sampling sites, the distal rectum, anal canal and internal anal sphincter. In the 15-day old rats the myenteric plexus of the distal rectum and anal canal was well outlined by numerous SP-immunoreactive varicose nerve fibres encircling immunonegative perikarya. In the circular muscle layer, nerve fibres and small nerve bundles ran parallel to the muscle cells, while in the longitudinal muscle layer, only occasional nerve fibres were seen. At the level of the internal anal sphincter, no myenteric ganglia were present. Here... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2928965 Fri, 23 Oct 2009 18:48:05 +0100 2928965 http://www.medworm.com/index.php?rid=2921871&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv6831731g71j326h%2F We describe two cases of tuberculous spondylitis in patients undergoing chronic hemodialysis therapy. They are IFN-γ assay diagnosed (QuantiFERON-TB Gold) and conservatively treated. Our cases suggest that IFN-γ assays equip clinicians with more accurate tools for tuberculosis control. A combination of T-SPOT.TB testing and MRI assessment may be the accurate method to diagnose tuberculous spondylitis in patients with end-stage renal disease. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0093-7Authors Kosta Kostov, Ministry of Interior Departments of Neurology 1606 Sofia BulgariaPlamen Yovchevski, Ministry of Interior Nephrology of Medical Institute 1606 Sofia BulgariaIvan Petrov, Ministry of Interior Departments of Neurology 1606 Sofia Bulgaria Jo... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2921871 Wed, 21 Oct 2009 22:28:13 +0100 2921871 http://www.medworm.com/index.php?rid=2918085&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F14t6v3n108p74371%2F Abstract  Bilateral caudate infarct is a very rare neurological situation, usually caused by small-artery disease resulting from a cardiac embolism. The most prominent clinical features of caudate vascular lesions are behavioral and cognitive abnormalities. We report here a case of bilateral infarction of the caudate nucleus and right parietal lobe with loss of consciousness and left hemiparesia resulting from left ventricular diastolic dysfunction (LVDD). A 50-year-old woman was admitted to our clinic with symptoms of mental status change. One day ago before appearing at our clinic, the patient was hospitalized because of food intoxication and diarrhea. Her neurological examination revealed that orientation-cooperation was impaired, and motor weakness was found in the left... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2918085 Wed, 21 Oct 2009 08:59:46 +0100 2918085 http://www.medworm.com/index.php?rid=2918087&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy75634586406q028%2F We report a case of postoperative hypoparathyroidism who developed severe hyperphosphatemia and associated hypocalcemia after bowel preparation with oral NaP. A 39-year old woman was admitted to the hospital because of multiple bone fractures. The diagnosis of primary hyperparathyroidism was confirmed. Further assays suggested Cushing’s disease and MRI disclosed a pituitary microadenoma. Considering the diagnostic suspect of multiple endocrine neoplasia type 1, computed tomography of abdomen was performed, showing a mass in the right adrenal. The patient underwent transsphenoidal surgery and then total parathyroidectomy. Despite total removal of the microadenoma by transsphenoidal surgery, there was no suppression in serum cortisol levels. So, an operation was scheduled for the adr... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2918087 Wed, 21 Oct 2009 08:59:45 +0100 2918087 http://www.medworm.com/index.php?rid=2918086&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F03l341594v771816%2F We report an unusual case of a 21-year-old woman with a leukemia in remission, in whom routine transthorasic echocardiographic examination demonstrated an incidental left ventricular mass. The patient underwent successful resection of the left ventricular mass under cardiopulmonary bypass through the left atrial approach. Histopathologic examination was diagnostic for myxoma. In this case, the presentation of the mass was atypical for two reasons: the tumour was a cardiac myxoma in the left ventricular localisation and in a patient with leukemia in remission. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0105-7Authors Asli Tanindi, Gazi University Faculty of Medicine Cardiovascular Medicine 06500 Ankara TurkeyGulten Tacoy, Gazi University Faculty of Medici... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2918086 Wed, 21 Oct 2009 08:59:45 +0100 2918086 http://www.medworm.com/index.php?rid=2918089&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff860376551126158%2F Abstract  Influenza contributes significantly to morbidity and mortality in the winter season. The aim of the study was to identify clinical signs and symptoms most predictive of influenza infection in children and adults with influenza-like illness. A prospective systematic sampling analysis of clinical data collected through sentinel surveillance system for influenza in 32 primary care centers and one tertiary care hospital in Slovenia during two consecutive influenza seasons (2004/2005 and 2005/2006) was carried out. Children and adults who had influenza-like illness, defined as febrille illness with sudden onset, prostration and weakness, muscle and joint pain and at least (cough, sore throat, coryza) were included and tested for influenza A and B virus, adenovirus, res... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2918089 Wed, 21 Oct 2009 08:59:44 +0100 2918089 http://www.medworm.com/index.php?rid=2918088&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp074r374894x1583%2F Abstract  The risk of carcinoma increases in patients with a 10-year or longer duration of ulcerative colitis (UC). To search for a more objective parameter to assess epithelial dysplasia. The study comprised 25 cases of longstanding UC: 7 cases with regenerative atypia, 7 with low grade dysplasia, 7 with high grade dysplasia, and 4 cases indefinite for dysplasia. The colonic biopsies obtained during endoscopy were stained with H&E to identify the aforementioned categories. Seventy-five sections from biopsy specimens were stained immunohistochemically to detect differences in the frequency and pattern of nuclei positive for the proliferation marker Ki67 and p53. In high grade dysplasia, the distribution of Ki67 positive cells was diffuse throughout the full length of the cr... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2918088 Wed, 21 Oct 2009 08:59:44 +0100 2918088 http://www.medworm.com/index.php?rid=2810999&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F52776263u3k772q5%2F Abstract  Anemia is an indisputable finding in patients scheduled for coronary artery bypass graft (CABG) that can occur any time preoperatively. In presence of severe coronary artery disease, anemia can dramatically affect surgical outcomes. Therefore, we conducted this study to determine the effect of low preoperative hemoglobin (Hgb) on postoperative outcome in patients who underwent coronary artery bypass graft (CABG). In all, 4432 patients who had undergone isolated CABG at Tehran Heart Center over the 2-year period from March 2006 to February 2008 were studied. All medical records of the aforementioned patients were derived from our hospital surgery data bank. After adjustment for confounders, the association of different preoperative levels of Hgb with risk of cardia... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2810999 Wed, 16 Sep 2009 11:57:19 +0100 2810999 http://www.medworm.com/index.php?rid=2811000&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv82270xp7661p306%2F Abstract  Lead exposure is a common public health problem. Exposure to the metal can cause hematological, gastrointestinal, rheumatological, endocrine, neurological and renal problems in humans. However, effects on the thyroid gland are controversial. We retrospectively investigated thyroid function parameters in 65 adult males who had been occupationally exposed to lead. We then compared the findings with those of 60 male patients who had no history of lead exposure or thyroid abnormalities, who served as the control group. The mean ages of the lead-exposed workers and the controls were 34.3 ± 7.9 and 32.9 ± 6.6 years respectively. Blood lead levels in the lead-exposed workers were significantly higher than in the control group. The lead-exposed workers were assigned to ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2811000 Wed, 16 Sep 2009 11:57:18 +0100 2811000 http://www.medworm.com/index.php?rid=2706749&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fku71763891h62501%2F Abstract  Fungal peritonitis is a rare but serious complication in patients with chronic renal failure on continuous ambulatory peritoneal dialysis (CAPD). The purpose of this study was to report the prevalence of fungal peritonitis in patients on CAPD in the Clinical Center-Nis (South Serbia) in the period from 1997 until the end of 2007. Fungal species were isolated in 66 cases (4.5%) of 1471 peritoneal fluid (PF) samples that we examined. During the study period, 22 (1.5%) cases of fungal peritonitis were registered. In 19 cases, Candida isolates were identified, Candida albicans (C. albicans) being the most common species (n=15). Two cases of fungal peritonitis caused by Aspergillus fumigatus and 1 possible case caused by Cladosporium cladosporioides (Cl. cladosporioides)... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2706749 Fri, 14 Aug 2009 17:05:58 +0100 2706749 http://www.medworm.com/index.php?rid=2661652&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fth56366v87034v10%2F This study was undertaken to investigate knowledge, attitudes and practices among HCWs towards blood borne pathogens. We carried out a cross sectional KAP (Knowledge, Attitudes and Practice) study, using self-administered questionnaire. The study population consisted of 127(23.6%) physicians, and 410 (76.4%) nurses and laboratory technicians. Factor analysis and conditional multiple logistic regression were used in statistical analysis. We found that the knowledge of the epidemiological characteristics of blood-borne infection, the risk of acquisition and available preventative measures among HCWs is insufficient. Doctors were more knowledgeable about the transmissibility of blood borne pathogens regarding sexual transmission after percutaneous exposure (odds ratio) OR=2.71; 95% (conf... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2661652 Thu, 30 Jul 2009 19:35:32 +0100 2661652 http://www.medworm.com/index.php?rid=2661653&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjw46010756517025%2F Abstract  The authors report on two multiple myeloma sibling pairs. In the absence of a known disease-specific marker one can only speculate on an explanation: is it because of inherited errors or is it related to the same environmental exposure, or both? In this study HLA typing and metabolizing enzyme polymorphism studies have been carried out with the aim of finding inherited similarities in the siblings or characteristics that might differ from the average population. Sibling pair 1 shared an HLA haplotype. Sibling pair 2 shared only HLA-B51, DR4, DRw53, DQ3. Sibling 1/1 was GSTT1 / GSTM1 null and GSTP1 Ile105Val; sibling 1/2 was a GSTT1 / GSTM1 heterozygote and GSTP1 Ile105Val; sibling 2/1 and 2/2 were GSTT1 heterozygotes and shared GSTM1 null / GSTP1 Ile105Ile. The sibl... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2661653 Thu, 30 Jul 2009 19:35:30 +0100 2661653 http://www.medworm.com/index.php?rid=2643114&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr40639kk0tq353q2%2F In this report, we describe a case of tuberculous bursitis-osteomyelitis of the wrist, in an elderly patient with rheumatoid arthritis and anti-TNFalpha (anti-Tumor Necrosis Factor alpha) treatment. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0078-6Authors Avgoustidis Nestor, National and Kapodistrian University of Athens Pathophysiology Department, Laikon General Hospital and Medical School 11527 Athens GreeceSipsas Nikolaos, National and Kapodistrian University of Athens Pathophysiology Department, Laikon General Hospital and Medical School 11527 Athens GreeceEvangelou Konstantinos, National and Kapodistrian University of Athens 1st Department of Pathology, Laiko General Hospital 11527 Athens GreecePikazis Dimitrios, National and Kapodistrian University o... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2643114 Sat, 25 Jul 2009 08:51:45 +0100 2643114 http://www.medworm.com/index.php?rid=2643113&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2871382127331q23%2F Abstract  The aim of the study was to determine the frequency and titers of anti-thyroid peroxidase (Anti-TPO), anti-thyroglobulin (Anti-TG), and anti-glutamic acid decarboxylase (Anti-GAD) antibodies in Turkish patients with type 1 diabetes mellitus (DM), and to compare the frequency of anti-TPO and anti-TG titers in the presence or absence of anti-GAD. A total of 104 patients including 56 males and 48 females with type 1 DM and their age-, gender-, and body mass index-matched control group, including 31 males and 27 females, 58 cases in total with an age range of 15-50 years, were recruited into this study. In patients with type 1 DM, positive anti-GAD was detected in 30.8% (n=32). In patients with positive anti-GAD, rate of positive anti-TPO was 37.5%; however, in patien... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2643113 Sat, 25 Jul 2009 08:51:45 +0100 2643113 http://www.medworm.com/index.php?rid=2643115&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh27u8hw3r2j73611%2F Abstract  The aim of the present experimental study was to determine and to compare the effects of vitamin E and of selenium on the blood flow to a wound region in rats, using the xenon-133 (133Xe) clearance technique. Burn wounds were made on the right thighs of rats followed by oral administration of vitamin E or selenium for a period of 10 days. The effect of vitamin E and of selenium individually on blood flow in the wound region was assessed before and after oral administration using the 133Xe clearance technique. Both vitamin E and selenium significantly increased the blood flow in the wound region (P<0.05). Our results in rats suggest that both vitamin E and selenium have beneficial effects on the skin wound healing process by increasing the skin blood flow. Con... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2643115 Sat, 25 Jul 2009 08:51:44 +0100 2643115 http://www.medworm.com/index.php?rid=2643117&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg25631246878188x%2F In conclusion, in cases of not typical pneumonia course, i.e. non-resolving or recurrent pulmonary infiltrates; relative mild clinical symptoms and moderate increased CRP level with multiple pulmonary infiltrates; blood eosinophilia and/or signs of airway obstruction eosinophilic pneumonia should be suspected and bronchoalveolar lavage and/or bronchoscopic lung biopsy performed. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0082-xAuthors Edvardas Danila, Allergology and Radiology of Vilnius University Clinic of Chest Diseases LT 08661 Vilnius LithuaniaJolita Norkūnienė, Gediminas Technical University Department of Mathematical Statistics of Vilnius LT 10223 Vilnius LithuaniaRemigijus Nargėla, Allergology and Radiology of Vilnius University Clinic of... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2643117 Sat, 25 Jul 2009 08:51:43 +0100 2643117 http://www.medworm.com/index.php?rid=2643116&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq503wn3266048j6q%2F Abstract  Diabetes is a chronic metabolic disease which can lead to numerous complications. One of these disturbances is cognitive function impairment. A group of 62 patients with type 1 and type 2 diabetes. There is a correlation between certain clinical features among diabetic patients and cognitive functions. Negative influence on cognitive functions have a higher level of total cholesterol, a higher level of LDL cholesterol, a lower level of HDL cholesterol concentration in the blood, a higher level of glucose after meals, a higher level of basic insulin dose and insulin dose taken just before the examination, longer duration of the diabetes and a lot of hypoglycemic episodes. There is no influence on cognitive functions from glucose levels before meals, the type of the... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2643116 Sat, 25 Jul 2009 08:51:43 +0100 2643116 http://www.medworm.com/index.php?rid=2599797&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy60qw6265109kt55%2F Abstract  We aimed to evaluate the risk factors for VRE colonization in neonatal intensive care units. In December 2007, we identified a neonate with VRE infection (urinary tract infection and we performed blood and stool cultures for VRE until the last colonized patient was discharged from our clinic. All the neonates hospitalized in NICU during December 2007 to January 2008. Active surveillance cultures for VRE fecal carriage was carried out in neonatal intensive care unit. Resistance to vancomycin was detected by the E-test method. Epidemiological data was recorded for all patients included in the study and was used for the risk factors. Totally 54 infants in NICU were screened for VRE colonization. Totally 11 infants (20%) were colonized with vancomycin-resistant entero... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599797 Mon, 13 Jul 2009 06:01:27 +0100 2599797 http://www.medworm.com/index.php?rid=2599794&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F02763583pl352u1h%2F Abstract  Quantitative ultrasound (QUS) is of increasing interest for evaluation of osteoporosis because, compared with dual-energy X-ray absorptiometry (DXA), it is portable, less expensive, and radiation-free. The aim of our study was to determine the sensitivity, specificity, and cut-off values of quantitative ultrasound parameters in identifying patients with osteoporosis compared to the World Health Organization (WHO) standard definition. We performed a cross-sectional investigational study of 73 subjects, and determined total hip and lumbar spine T-scores by dual-energy X-ray absorptiometry (DXA) (Prodigy Advance Lunar-GE). The QUS parameters (broadband ultrasound attenuation [BUA], speed of sound, bone mineral density, the stiffness index, and QUS T-score) were deter... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599794 Mon, 13 Jul 2009 06:01:27 +0100 2599794 http://www.medworm.com/index.php?rid=2599799&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff04u06451427v557%2F Abstract  To determine the effects of EE/CA (Ethinylestradiol/ Cyproterone Acetate) and EE/CA-metformin treatments on the asymmetric dimethylarginine (ADMA) levels in women with PCOS (Polycystic Ovary Syndrome). Among 43 patients diagnosed with PCOS, one study arm (n=22) was administered (35 µg EE, 2mg CA) and the other (n=21) was administered (35 µg EE, 2mg CA plus 1700mg metformin). Serum ADMA, lipid profile, androgens, insulin, and HOMA-IR (Homeostatic Model Assessment of Insulin Resistance ) values were assessed prior to treatment and after 3 months of therapy. A significant reduction in ADMA levels relative to pre-treatment in the EE/CA+metformin group (1.2±0.4 vs 0.95±0.4, p=0.016) compared to the EE/CA group (1.0±0.5 vs 1.03±0.4, p >0.05). Andogens, insulin ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599799 Mon, 13 Jul 2009 06:01:26 +0100 2599799 http://www.medworm.com/index.php?rid=2599802&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F712t534311822741%2F Abstract  Chlorfenvinphos is an organophosphate insecticide, posing a risk to those who are professionally involved in its production and use in agriculture, as well as to the general population. Organophosphates (OPs) are the class of insecticides, whose primary target is acetylcholinesterase (AChE) that hydrolyzes acetylcholine, a major neurotransmitter at the central and peripheral neuronal synapses. Moreover, many authors postulate that these compounds, both in acute and chronic intoxication, change the activities of antioxidative enzymes, thus leading to the enhancement of lipid peroxidation in many tissues. In the current study, animals received once a day, intragastrically with a stomach tube, 0.1ml/100g of olive oil (control groups) and oil solution of chlorfenvinph... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599802 Mon, 13 Jul 2009 06:01:25 +0100 2599802 http://www.medworm.com/index.php?rid=2599806&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F660l41n6333p4628%2F In conclusion, this trial once more demonstrated that taxane-based adjuvant chemotherapy was effective and safe in lymph node-positive, early-stage Turkish breast cancer patients. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0075-9Authors Ahmet Alacacioglu, Izmir Research and Training Hospital Medical Oncology 35360 Bozyaka, Izmir TurkeyBaha Zengel, Izmir Research and Training Hospital Clinic of 1.General Surgery 35360 Bozyaka, Izmir TurkeyAli Galip Denecli, Izmir Research and Training Hospital Clinic of 1.General Surgery 35360 Bozyaka, Izmir Turkey Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599806 Mon, 13 Jul 2009 06:01:23 +0100 2599806 http://www.medworm.com/index.php?rid=2599804&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Feh1p01511p6m1989%2F Abstract  Resistin has been associated with obesity and type 2 diabetes. The elevated serum resistin level in human diabetes is often associated with a pro-inflammatory milieu. In vitro data suggest that C-reactive protein (CRP) significantly increases resistin expression in cultured human PBMC, yet the relationship in vivo is largely unknown. The purpose of this study was to determine the concentrations of CRP and resistin in women with polycystic ovary syndrome (PCOS) and to clarify whether or not there are correlations between CRP and resistin levels that have not previously been studied in PCOS in the context of resistin. Serum resistin and hsCRP levels of forty-five women with PCOS were analyzed. Compared with the control group, women with PCOS had significantly higher... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599804 Mon, 13 Jul 2009 06:01:23 +0100 2599804 http://www.medworm.com/index.php?rid=2599808&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm40733t361784154%2F In conclusion, our meta-analysis showed the significance of genetic alterations in the folate metabolism genes in maternal susceptibility to DS offspring. Our results suggest that the importance of folate supplementation to women in reproductive age in prevention of non-disjunction be revised. Further genetic studies on a combined effect of multiple folate metabolism genes is recommended. Additionally, more thorough studies on the haplotype analyses of genes is recommended as well, especially in populations that have not yet been investigated thus far. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0055-0Authors Igor Medica, University Medical Centre Ljubljana Institute of Medical Genetics, Department of Obstetrics and Gynecology 1000 Ljubljana Sloveni... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599808 Mon, 13 Jul 2009 06:01:21 +0100 2599808 http://www.medworm.com/index.php?rid=2599810&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl1l45t74ln4t18m2%2F Abstract  The interaction between cancer cells and platelets has been known for a long time. Although platelet indices have been also investigated in several clinical settings, it has not been exactly demonstrated in cancer patients. We investigated platelet indices in colorectal cancer patients and compared with healthy subjects. Two hundred and twenty-one colorectal cancer patients and 110 healthy subjects were enrolled into the retrospective study. Data were obtained from computerized medical records of our hospital. Medical record review was performed for all patients regarding thrombocyte indices. Platelet count (325.000/mm3 ± 265.000/mm3 vs 267.000/mm3 ± 67.000/mm3; p=0.025; respectively) and plateletcrit (Pct) (0.25% ± 0.10 vs 0.21 ± 0.05; p<0.001; respectivel... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2599810 Mon, 13 Jul 2009 06:01:19 +0100 2599810 http://www.medworm.com/index.php?rid=2565449&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft827011h69040030%2F Abstract  To investigate CD4+CRTH2+ cells in peripheral blood in advanced stage non small cell lung cancer (NSCLC) patients. Forty-six patients with advanced stage NSCLC, who are chemotherapy or radiotherapy naïve, and 17 healthy volunteers, were enrolled in this study. The study was performed using flow cytometry and a complete blood cell counter analyser. CD4+ T cell percentage, CD4/CD8 ratio, CRTH2+CD4+ cell percentages, counts, and mean fluorescein intensity (MFI) and hematological parameters were evaluated in both groups. A survival analysis was performed to compare the patients with high CD4+CRTH2+ cell percentage and those with low CD4+CRTH2+ percentage. CD4+ T cell percentage in total lymphocytes and the CD4/CD8 ratio were lower in the patient group than in the con... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565449 Wed, 01 Jul 2009 06:23:38 +0100 2565449 http://www.medworm.com/index.php?rid=2565448&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk337164051202628%2F Abstract  Quality of life (QoL) and individual perception of health has become a subject of great interest in Lithuania. The relationships between country residence, socio-economic status (SES), and QoL have not been well characterized among the Lithuanian urban and rural populations. The aim of the study was to assess the influence of country residence and SES on QoL in Lithuanian urban and rural population adjusting for the influence of other known determinants of QoL. The study population was randomly selected from 1193 urban and 264 rural men and women aged 45–72 years and have been filled in the self-administered the WHOQOL-100 questionnaire. The survey participation rate was 62.8%. Psychometric evaluation of the WHOQOL-100 showed good internal reliability of Cronbac... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565448 Wed, 01 Jul 2009 06:23:38 +0100 2565448 http://www.medworm.com/index.php?rid=2565451&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj053151428886x72%2F We present a case of a young woman with acute pancreatitis secondary to an overdose of nifedipine and acetaminophen in a suicide attempt. We excluded other causes of acute pancreatitis by clinical history, serum toxicology, serology, and abdominal imaging. The most likely underlying pathophysiological mechanism was ischemic injury of the pancreas secondary to severe collapse induced by nifedipine and possible acetaminophen-induced direct pancreatotoxicity. The pancreatitis resolved with treatment that included continuous veno-venous haemofiltration in an intensive care unit. Emergency and intensive care units should be aware of this unusual complication of such poisoning. To our knowledge, this is the first reported association between massive nifedipine overdose and acute pancreatit... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565451 Wed, 01 Jul 2009 06:23:37 +0100 2565451 http://www.medworm.com/index.php?rid=2565450&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa27rx73g77038631%2F This report presents these rare findings made by conventional radiography, computerized tomography (CT), and High-resolution CT (HRCT) of a 16-year-old female patient with fatal Gaucher’s disease. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0062-1Authors Meltem Ceyhan, Departments of Radiology Ondokuz Mayis University 55139 Samsun TurkeyFatma Cakmak Celik, Departments of Pediatrics Ondokuz Mayis University 55139 Samsun TurkeyMuzaffer Elmali, Departments of Radiology Ondokuz Mayis University 55139 Samsun TurkeyNevzat Gurmen, Departments of Radiology Ondokuz Mayis University 55139 Samsun Turkey Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565450 Wed, 01 Jul 2009 06:23:37 +0100 2565450 http://www.medworm.com/index.php?rid=2565452&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F90h54g6127911188%2F Abstract  Recent advancements in curative-intent therapies have led to dramatic improvements in breast cancer-specific mortality but at the direct expense of increased risk of cardiovascular-related mortality. The use of radiation therapy has led to significant improvements in survival for patients treated for breast cancer. However, as patients live longer, the potentially serious adverse effects of radiation on the heart have raised concerns. Coronary artery disease following irradiation is encountered rarely but is one of the most devastating treatable complications.In this article we review the cardiac complications associated with radiation therapy. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0068-8Authors Turgay Celık, Gulhane Military ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565452 Wed, 01 Jul 2009 06:23:35 +0100 2565452 http://www.medworm.com/index.php?rid=2565454&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8223655406441022%2F Abstract  The retrospective cost analysis estimates direct in-patient costs and length of stay (LOS) in hospital for acute heart failure (AHF). Patients were hospitalized with acute decompensation (ADHF) or de novo AHF in the Faculty Hospital Brno in 2005 and 2006. Burden incurred is divided to standard cardiology unit (SCU) and intensive care unit (ICU). In-patient care costs include flat rate of admission, stay and medicinal procedures. The pharmaceuticals are included in daily in-patient rate; angiography, revascularizations and antiarrhythmic interventions are calculated separately. In total, 734 patients (57% male, mean age 71.7 years) with AHF were analyzed. De novo AHF (58.6%) was more common than ADHF; according to the clinical classification AHF with mild signs and... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565454 Wed, 01 Jul 2009 06:23:34 +0100 2565454 http://www.medworm.com/index.php?rid=2565453&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1268mu3k1470w378%2F Abstract  The aim of our study was to establish that the incidence of perioperative cardiac complications were in direct correlation with level of operative risk in coronary patients undergoing open abdominal nonvascular surgery with general anesthesia. Our prospective observational clinical study was composed of a group of 111 consecutive patients with angiographically-verified coronary artery disease, who were operated on at the University Clinical Center of Serbia. The patients were classified into four stratification subgroups by “Goldman’s Cardiac Risk Index” (CRI) in relation to the incidence of perioperative cardiac complications. Electrocardiography was performed immediately after surgery, on postoperative days 1, 2, 7 and one day before discharge from the hos... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565453 Wed, 01 Jul 2009 06:23:34 +0100 2565453 http://www.medworm.com/index.php?rid=2565455&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyrxq11l102kj0r57%2F Abstract  Osteoprotegerin (OPG)/“receptor activator of nuclear factor kappa B-ligand” (RANKL) system has an important role in the remodeling of bone through regulation of osteoclastogenesis. We aimed to detect OPG and RANKL levels, particularly in obese children in the pubertal period and to investigate whether these parameters correlate with insulin resistance in childhood. Our study included 66 obese children ranging in age from 9.1 to 16 years, and 22 non-obese children ranging in age from 10.5 to 16 years. Blood glucose, insulin, total cholesterol, HDL cholesterol, and LDL cholesterol levels were measured for all cases; HOMA-IR, Quicki index and atherogenic index were calculated. Serum OPG and RANKL levels were also measured. OPG and RANKL levels did not show any di... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565455 Wed, 01 Jul 2009 06:23:33 +0100 2565455 http://www.medworm.com/index.php?rid=2565457&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F73m1857683g620j0%2F Abstract  Our case involves a 53 year old woman. Three years ago, she was investigated because of normal hemoglobin levels despite very a low erythrocyte count, which was revealed during the preoperative evaluation for ovarian cyst operation. The Direct Coombs test was found to be positive against complement and negative against IgG. Cold agglutinin titer was 1/448 (+). Due to the polyclonal IgM increase, secondary cold agglutinin disease (CAD) was considered but no factor could be found that would lead to cold agglutinin disease. During the post-operative follow-up, cold agglutinin titers increased with fluctuations in the patient. Twenty-four months after transabdominal hysterectomy and bilateral salpingooopherectomy operation, diagnosis of Hashimoto disease was made upon... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565457 Wed, 01 Jul 2009 06:23:32 +0100 2565457 http://www.medworm.com/index.php?rid=2565456&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp4v50222w7jqu781%2F Abstract  It is unusual to find a giant invasive basal cell carcinoma in the occipital region of the head. We are presenting a case of basal cell carcinoma invading and eroding occipital bone, managed with an unusual scalp reconstruction method. A 69-year-old female presented with a 16x19 cm diameter tumour in the occipital region. Preoperative biopsy revealed a basal cell carcinoma. A complete surgical excision of the tumour was performed in one-step surgery and tissue defect was reconstructed by a pedicle latissimus dorsi musculocutaneous flap. Our case shows that this distant pedicle flap is safe and reliable, and should be revised as the option for the occipital region reconstruction. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0069-7Authors... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565456 Wed, 01 Jul 2009 06:23:32 +0100 2565456 http://www.medworm.com/index.php?rid=2565459&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe1p46778421n140v%2F This study showed that the transabdominal ultrasound evaluation of the fatty liver is a quite good predictor, perhaps sufficient for most purposes, for the estimation of the severity of liver steatosis in the moderate to severe range. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0067-9Authors Ioan Sporea, University of Medicine and Pharmacy Timişoara Department of Gastroenterology and Hepatology 300736 Timişoara RomâniaRoxana Şirli, University of Medicine and Pharmacy Timişoara Department of Gastroenterology and Hepatology 300736 Timişoara RomâniaElena Başa, University of Medicine and Pharmacy Timişoara Department of Gastroenterology and Hepatology 300736 Timişoara RomâniaMaria Cornianu, University of Medicine and Pharmacy Timişoara Departm... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565459 Wed, 01 Jul 2009 06:23:31 +0100 2565459 http://www.medworm.com/index.php?rid=2565458&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnv6077301pj43282%2F Abstract  We compared the intensity of staining of interstitial cells (ICs) and neural tissue in the lower urinary tract of rabbits with diabetes with the intensity in normal subjects. Diabetes was induced by injecting alloxane (65mg/kg) in adult male rabbits. After 3 days, rabbits with a blood glucose level >300 mg/dL were considered to have diabetes. After 8 weeks, the rabbits were killed, and tissue specimens from the bladder, prostate and urethra were obtained. ICs were stained with anti-human CD117 (c-kit) rabbit polyclonal antibody, and neural tissue was stained with synaptophysin. The streptavidin-biotin method was used for immunohistochemical staining. The intensity of c-kit and synaptophysin staining were scored as negative (0), weak (+), moderate (++), and stro... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565458 Wed, 01 Jul 2009 06:23:31 +0100 2565458 http://www.medworm.com/index.php?rid=2565460&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy10l1211g11t2q1j%2F Abstract  The present study deals with the application of two major multivariate statistical approaches - Cluster Analysis (CA) and Principal Components Analysis (PCA) as an option for assessment of clinical data from diabetes mellitus type 2 patients. One hundred clinical cases of patients are considered as object of the statistical classification and modeling, each one of them characterized by 34 various clinical parameters. The goal of the study was to find patterns of similarity, both between the patients and the clinical tests. Each group of similarity is interpreted revealing at least five clusters of correlated parameters or five latent factors, which determine the data structure. Relevant explanation of the clustering is found based on the pattern of similarity like... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2565460 Tue, 30 Jun 2009 15:55:19 +0100 2565460 http://www.medworm.com/index.php?rid=2480195&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh7701x2m313g053n%2F We present a case of successfully treated gross pericardial effusion and tamponade in a 22-week pregnant woman with hypothyroidism. The patient was treated by pericardial drainage with further treatment of hypothyroidism with levothyroxine. During the follow-up pregnancy was uncomplicated without recurrence of pericardial effusion and successful delivery of full-term baby. We conclude that careful monitoring of thyroid functional tests and proper management should be performed in pregnant women with hypothyroidism to prevent cardiac complications of the disease, like pericardial effusion and tamponade. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0060-3Authors Talay Kudaiberdiev, National Center of Cardiology and Therapy Scientific Research Institute of ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2480195 Wed, 10 Jun 2009 11:36:39 +0100 2480195 http://www.medworm.com/index.php?rid=2480197&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F86873l1k97620p67%2F This study aimed to determine whether magnesium as a lightweight and biocompatible metal is suitable as a biomaterial for spinal implants based on its MRI artifacting behavior. To compare artifacting behaviors, we implanted into one porcine cadaveric spine different test spacers made of magnesium, titanium and CFRP. All test spacers were scanned using 2 T1-TSE MRI sequences. The artifact dimensions were traced on all scans and statistically analyzed. The total artifact volume and median artifact area of the titanium spacers were statistically significantly larger than magnesium spacers (p < 0.001), while magnesium and CFRP spacers produced almost identical artifacting behaviors (p > 0.05). Our results suggest that spinal implants made with magnesium alloys will behave more like... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2480197 Wed, 10 Jun 2009 11:36:37 +0100 2480197 http://www.medworm.com/index.php?rid=2480196&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg7vw170x25771222%2F Abstract  A 13-year-old boy with atrial septal defect and tricuspid valve abnormality was reported. He had crepitan ralles and signs of heart failure. He was treated with digital, diuretic and antimicrobial therapies. After clinical improvement he underwent surgery. The atrial septal defect was closed, and ringplasty was applied to the tricuspid valve. After the operation, he could not be extubated because of respiratory failure. On the seventh day following the surgery, he developed pneumothorax and hyportension and died. Postmortem examination showed bilateral diffuse pulmonary tuberculosis. The aim of this report is to emphasise the association of tuberculosis and congenital heart disease. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0061-2Aut... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2480196 Wed, 10 Jun 2009 11:36:37 +0100 2480196 http://www.medworm.com/index.php?rid=2434573&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8015287058w47466%2F Abstract  Incisional hernias and abdominal-wall defects consume large amounts of healthcare resources. Use of mesh is effective in treatment of these disorders and can decrease the rate of recurrence. This experimental study focused on the safety of mesh use in the setting of malnutrition, a condition that impairs wound healing. Rats were divided into two groups: normally fed and food-restricted. An abdominal-wall defect, 2 by 2 cm, was covered with polypropylene mesh, 2.5 by 2.5 cm. After sacrifice of the rats at the 21st and 60th days, tissue samples were sent for tensiometric and histopathological studies. No significant difference in infectious complications was observed between the two groups. Tensiometry revealed no significant differences between the groups. On histo... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2434573 Sun, 24 May 2009 05:59:48 +0100 2434573 http://www.medworm.com/index.php?rid=2434575&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx30211753k450875%2F Abstract  Gastric volvulus (GV) is a rare pathological entity, which is difficult to diagnose, may rapidly progress to infarction and necrosis of the stomach, and can be fatal. A 68-year-old woman presented to the surgical outpatient clinic of Istanbul University, Istanbul Faculty of Medicine, in August, 2006, with a 3-month history of nausea, vomiting, and recurrent abdominal pain. Physical examination revealed epigastric tenderness, but otherwise within normal limits. An urgent abdominal computed tomographic examination revealed only a paraesophageal hernia. A mesenteroaxial gastric volvulus with a large paraesophageal hernia was found on laparoscopy. The surgical procedure involved derotation of the stomach and closure of the paraesophageal hernia with a dual V-shaped gra... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2434575 Sun, 24 May 2009 05:59:46 +0100 2434575 http://www.medworm.com/index.php?rid=2434574&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff561wr2165k25356%2F We report a patient who had HHT with severe heart failure (New York Heart Association [NYHA] class III-IV) and pulmonary hypertension caused by an hepatic arteriovenous fistula. After successful transarterial embolisation of the right branch of the hepatic artery with polyvinyl alcohol (PVA) particles and coils, 4 to 7 mm in size, the patient was discharged with functional class II (NYHA) heart failure. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0028-3Authors Sadık Kadri Açikgöz, Gazi University Faculty of Medicine Cardiology Department 06500 Ankara TurkeyGülten Taçoy, Gazi University Faculty of Medicine Cardiology Department 06500 Ankara TurkeyBaran Önal, Gazi University Faculty of Medicine Radiology Department 06500 Ankara TurkeyBeytullah Yıldı... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2434574 Sun, 24 May 2009 05:59:46 +0100 2434574 http://www.medworm.com/index.php?rid=2434576&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe3538213433v7668%2F In conclusion, elevated serum cTnT levels after epirubicin-containing adjuvant chemotherapy for stage 2 and stage 3 breast cancer, predict future cardiac dysfunction with moderate sensitivity and poor specificity. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-008-0093-zAuthors Refik Erdim, Florence Nightingale Hospital 34119 Istanbul TurkeyAydin Celiker, Marmara University Hospital 34633 Istanbul TurkeyGökmen Gemici, Namik Kemal University Hospital 59030 Tekirdag TurkeySena Tokay, Marmara University Hospital 34633 Istanbul TurkeyGözde Ülfer, Marmara University Hospital 34633 Istanbul TurkeyFuat Dede, Marmara University Hospital 34633 Istanbul TurkeySerdar Turhal, Marmara University Hospital 34633 Istanbul TurkeyAhmet Oktay, Marmara University Hospital 34... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2434576 Sun, 24 May 2009 05:59:45 +0100 2434576 http://www.medworm.com/index.php?rid=2429886&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk25776xt23896m11%2F We report the case of a 52-year-old woman who presented with a several-year history of palpitation (exacerbated by emotional stress and physical activity) and recent development of atypical chest pain. An investigation was undertaken to diagnose the patient’s problem and to recommend the best possible therapy. Transthoracic echocardiography and a computerized axial tomography scan showed evidence of complete absence of the pericardium, which is a rare congenital heart defect. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0018-5Authors Arezou Zoroufian, Tehran University of Medical Sciences Echocardiography department, Tehran Heart Center 1411713138 Tehran IranShapour Shirani, Tehran University of Medical Sciences Radiology department, Tehran Heart Center ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2429886 Wed, 20 May 2009 05:55:09 +0100 2429886 http://www.medworm.com/index.php?rid=2429887&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F33ql06m626536524%2F Abstract  Parkinson’s disease (PD) belongs to group of neurodegenerative diseases. PD diagnosis is clinical, based on these signs: tremor, rigidity, bradykinesia, akinesia or hypokinesia. The aim of the work was to determine the frequency of separate clinical forms of Parkinson’s disease and difficulties at this disease diagnosis. After examining 267 patients, foreseen clinical criterion of Parkinson’s disease correspond 202 (44.0% persons) − 115 women and 87 men and for 65 patients diagnosis of PD was not confirmed, because they did not correspond with accepted criteria of Parkinson’s disease. While analyzing clinical peculiarities of disease we ascertained that rigidity-tremor form of disease prevailed for 152 (75.2%, 86 women and 66 men) patients. The rigidity ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2429887 Wed, 20 May 2009 05:55:06 +0100 2429887 http://www.medworm.com/index.php?rid=2419608&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu842552210115505%2F We report a 71-year-old Turkish woman with erythematous lesions, which included widespread, erythematous macules of various sizes on the chest, abdomen, and back on both sides of her body. Fine white scales covered some of the lesions. Hepatomegaly and bilateral hilar lymphadenopathy were also observed. Biopsy specimens of the skin showed dermal, noncaseating, epitheloid granulomas. The diagnosis, based on correlation of the clinical presentation and histopathological findings, was ichthyosiform sarcoidosis with systemic involvement. The difference between our case and other cases of ichthyosiform sarcoidosis described in the literature is that ours involved only the trunk and not the extremities. We are presenting this case because it is an interesting and rare variant of ichthyosi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419608 Sun, 17 May 2009 06:48:03 +0100 2419608 http://www.medworm.com/index.php?rid=2419609&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F148224g073688689%2F We report two cases of aplastic anaemia having a different aetiology. The diagnostic work-up and the therapeutic management for each case are described below. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0024-7Authors Maria Scalzone, Catholic University of Rome Division of Paediatric Oncology 00168 Rome ItalyPaola Coccia, Catholic University of Rome Division of Paediatric Oncology 00168 Rome ItalyPalma Maurizi, Catholic University of Rome Division of Paediatric Oncology 00168 Rome ItalyGiorgio Attinà, Catholic University of Rome Division of Paediatric Oncology 00168 Rome ItalyLucia Liotti, Catholic University of Rome Division of Paediatric Oncology 00168 Rome ItalyMaria Giuseppina Cefalo, Catholic University of Rome Division of Paediatric Oncology 0016... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419609 Fri, 15 May 2009 06:02:54 +0100 2419609 http://www.medworm.com/index.php?rid=2419610&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F851323j34628jr57%2F Abstract  Severe and composite defects of the nose due to trauma or excision of neoplasms can cause significant functional and aesthetic problems. It has been known that nasal stents have been used to maintain the nasal patency and nostril shape for a long time. Recently, nasal prosthesis was introduced as a method to solve aesthetic problems of the patients who had an amputated nose. In the present study, nasal prosthesis combined with nazal stents was used to camouflage the nasal disfigurement and to maintain the nasal patency in two adult female patients. Functional and aesthetic results was accepted as satisfactory by both the patients and the physicians. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0034-5Authors Yumuşhan Günay, Haydarpa�... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419610 Fri, 15 May 2009 06:02:53 +0100 2419610 http://www.medworm.com/index.php?rid=2419611&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy8742045j429r326%2F Abstract  The aim of this study was to evaluate vitamin B12 and folate levels, thyroid functions, sex hormones and bone mineral density in idiopathic epileptic patients taking oxcarbazepine as monotherapy. Newly diagnosed pediatric patients with idiopathic partial epilepsy taking oxcarbazepine (OXC) as monotherapy were enrolled in this study. The pre-treatment and 6 months post-treatment values of vitamin B12, folate, thyroid functions, sex hormones, and bone mineral density (BMD) were obtained from all patients. A total of 32 patients (22 (68.8%) males and 10 (31.2%) females) were included in this study. The mean age was 7.4 ± 3.2 years (range: 2–14 years). There were no significant differences between the pre-treatment and 6 months post-treatment values of vitamin B12,... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419611 Fri, 15 May 2009 06:02:52 +0100 2419611 http://www.medworm.com/index.php?rid=2419613&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn16830807728264n%2F Abstract  To determine if delaying the primary precutaneous coronary intervention (PCI) for >6 hours for acute coronary syndrome with preserved ST elevation (STE-ACS) affects the PCI angiography effectiveness and clinical prognosis. The PCI was performed: for 71% of patients <6h (group 1), for 29% of patients >6h from the beginning of pain (group 2). For 1% of patients from group 1 and 3.4% of patients from group 2, no passage has been opened in the artery after STE-ACS. In spite of opening the passage mechanically, the phenomenon of lack of tissue reflow occurred in 2.7% of patients from group 1 and 12% of patients from group 2. Dangerous ventricular arrhythmias occurred more frequently in patients from group 2, including VF, asystole, haemodynamic complications c... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419613 Fri, 15 May 2009 06:02:51 +0100 2419613 http://www.medworm.com/index.php?rid=2419612&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7855844080k51u55%2F In this study, we aimed to determine the seizure relapse rates and the associated risk factors for seizure relapse in childhood epilepsy. Two-hundred sixty-six epileptic patients who discontinued the antiepileptic drug therapy after a seizure-free period of at least two years, were enrolled into the study. The data of the patients regarding sex, febrile convulsion history, family history, age at onset, type of epilepsy, total number of seizures and antiepileptic drugs, seizures during treatment, mental status, first and last electroencephalography, brain imaging findings, etiological factors and seizure relapse in the first two years after antiepileptic drug withdrawal were obtained from the patients’ files. Univariate logistic regression analysis was performed for each variable. T... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419612 Fri, 15 May 2009 06:02:51 +0100 2419612 http://www.medworm.com/index.php?rid=2419614&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe18874548h1128x5%2F Abstract  Transfusion after cardiac surgery is very common. This rate varies between institutions and has remained high despite established transfusion guidelines. We analyzed our database of patients who underwent isolated CABG (Coronary Artery Bypass Graft) to determine the predictive factors of homologous transfusion and associated postoperative morbidity, mortality and resource utilization. All 14,152 patients who underwent first-time isolated CABG, with or without cardiopulmonary bypass (CPB) who had postoperative homologous transfusion between February 2002 and March 2008 in Tehran Heart Center, were evaluated retrospectively. Overall, 16.5% of patients received transfusion. Transfused patients demonstrated a significantly higher incidence of postoperative complicatio... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419614 Fri, 15 May 2009 06:02:50 +0100 2419614 http://www.medworm.com/index.php?rid=2419616&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd36871417v135807%2F This study demonstrated that there was a significant difference in salivary gland function between patients with allergic rhinitis and healthy controls, which can easily be evaluated by [99mTc] pertechnetate salivary gland scintigraphy. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0041-6Authors Ozgur Yoruk, Ataturk University Department of Otorhinolaryngology, School of Medicine 25240 Erzurum TurkeyBedri Seven, Ataturk University Department of Nuclear Medicine, School of Medicine 25240 Erzurum TurkeyErhan Varoglu, Ataturk University Department of Nuclear Medicine, School of Medicine 25240 Erzurum TurkeyHarun Ucuncu, Ataturk University Department of Otorhinolaryngology, School of Medicine 25240 Erzurum TurkeyAli Sahin, Ataturk University Department of Nu... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419616 Fri, 15 May 2009 06:02:49 +0100 2419616 http://www.medworm.com/index.php?rid=2419615&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw5326473745172m3%2F We describe the utilization of computer-assisted lateral UKA placement for lateral knee osteoarthritis with a valgus malalignment of 10°. Navigation allows for a dynamic intraoperative visualisation of the mechanical axis, as well as for accurate component positioning and overall postoperative limb alignment. The systems allow the knee position to be captured with appropriate tension in extension and flexion prior to making definite cuts. Postoperatively, no instabilities occurred with a precise component placement. Navigation can be used in rare cases for lateral UKA. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0051-4Authors Daniel Kendoff, Hospital for Special Surgery Orthopaedic Department 10021 New York USAPaolo Di Benedetto, Università degli... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419615 Fri, 15 May 2009 06:02:49 +0100 2419615 http://www.medworm.com/index.php?rid=2419617&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv12g401u63gj2302%2F Abstract  The association of elevated serum uric acid (hyperuricemia, gout) with the presence of classical coronary risk factors and coronary artery disease (CAD) or myocardial infarction (MI) has been analysed in many epidemiological studies. Numerous studies have revealed that hypertension, high body mass index (BMI), lipid disorders (especially raised triglyceride (TG) levels and low high dense lipoprotein cholesterol (HDL-C) level), and increased creatinine or insulin levels have caused hyperuricemia. Gout has often occurred with typical disorders for the metabolic syndrome X. Significant correlation of the serum uric level and the CAD presence and severity of coronary atherosclerosis confirmed by coronary angiography has been observed in women. Hyperuricemia has also i... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419617 Fri, 15 May 2009 06:02:48 +0100 2419617 http://www.medworm.com/index.php?rid=2419619&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F73k3166710422h30%2F Abstract  Palliative care aims at improving the patient’s quality of life. The assessment of this quality of life (QoL) is crucial for the evaluation of palliative care outcome. Many patients require hospital admissions for symptom control during their cancer journey and most of them die in hospitals, although they would like to stay at home until the end of their lives. In 1986, the European Organization for Research and Treatment (EORTC) initiated a research programme to develop an integrated, modular approach for evaluating the quality of life of patients participating in international clinical trials. This questionnaire measures cancer patients’ physical, psychological and social functions and was used in a wide range of clinical cancer trials with large numbers of ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419619 Thu, 14 May 2009 07:04:49 +0100 2419619 http://www.medworm.com/index.php?rid=2419618&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp457851x575u1n08%2F Abstract  The report by Gumaste et al. [Gastroenterology 1991;101:1361–1366] that the lipase/amylase ratio (Lip/Amy) could be a new index distinguishing acute episodes of alcoholic (Lip/Amy >2) from nonalcoholic pancreatitis (Lip/Amy <2), with the critical value being Lip/Amy =2, has been followed by some debate between supporters and opponents. By comparing the Lip/Amy in a group of 16 carefully selected patients with mild acute gallstone-related (biliary) pancreatitis with that in a reference group of 44 controls, this study examines whether or not this ratio could be a useful index for diagnosing biliary pancreatitis. Considering that both pancreatic and hepatobiliary systems are blocked by stones, hepatic biochemical parameters such as serum levels of aspartate ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419618 Thu, 14 May 2009 07:04:49 +0100 2419618 http://www.medworm.com/index.php?rid=2419621&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn72586270xn3h826%2F In conclusions, rectus abdominis myocutaneous flap reconstruction seems to be an ideal option for the large defects resulting from exenteration operations in patients with previous perineal radiation. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-008-0080-4Authors Ates Karateke, Zeynep Kamil Teaching Hospital Department of Obstetrics and Gynecology 34590 Istanbul TurkeyCetin Cam, Zeynep Kamil Teaching Hospital Department of Obstetrics and Gynecology 34590 Istanbul TurkeyCem Celik, Zeynep Kamil Teaching Hospital Department of Obstetrics and Gynecology 34590 Istanbul TurkeyBahar Baykal, Zeynep Kamil Teaching Hospital Department of Obstetrics and Gynecology 34590 Istanbul TurkeyOzgur Aydin Tosun, Zeynep Kamil Teaching Hospital Department of Obstetrics and Gynecolog... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419621 Thu, 14 May 2009 07:04:48 +0100 2419621 http://www.medworm.com/index.php?rid=2419620&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxv615j833443tx67%2F This study has goals of examining whether pre-eclampsia may lead to an increase of elastic tissue fibers in blood vessel walls of placental stem villi or whether there are differences in the thickness of blood vessel walls within these villi when compared to normotensive pregnant women. Non-infarcted placental tissue samples from 28 participants with uncomplicated pregnancies and 26 patients with pre-eclampsia were obtained. After routine histological procedures, the sections were processed either for conventional Verhoeff staining for the demonstration of elastic fiber system. Paraffine sections from placenta biopsies prepared for light microscopic examination were gathered. In uncomplicated pregnancies, terminal villi blood vessels were observed with no stained elastic tissue fiber... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419620 Thu, 14 May 2009 07:04:48 +0100 2419620 http://www.medworm.com/index.php?rid=2419622&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F66911230727w7107%2F Abstract   Alcaligenes xylosoxidans is non-fermenting gram-negative bacilli found in soil and water. It is an aerobic bacterium in the genus Achromobacter. This bacterium is motile, oxidase positive, and catalase positive, which is isolated uncommonly from clinical specimens. In the present paper, we report a case of meningitis associated with A. xylosoxidans in a 38-year-old male patient post neurosurgery. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0031-8Authors Burcin Ozer, Mustafa Kemal University School of Medicine, Department of Microbiology and Clinical Microbiology 31100 Hatay TurkeyYurdal Serarslan, Mustafa Kemal University School of Medicine, Department of Neurosurgery 31100 Hatay TurkeyNizami Duran, Mustafa Kemal University School of ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419622 Thu, 14 May 2009 07:04:46 +0100 2419622 http://www.medworm.com/index.php?rid=2419624&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl10421h54t50m785%2F Abstract  Colorectal cancer ranks third as the most common malignancy in the United States and represents the second leading cause of cancer-related mortality. The appendix is thought to have a productive effect against colorectal carcinoma by the immune function based on its association with substantial lymphatic tissue. But, an appendectomy is still the most commonly performed emergency surgical procedure. It is aimed to assess the association between colorectal cancer and appendicectomy. The medical records of 455 patients who received medical and/or surgical treatment with the diagnosis of colorectal carcinoma in two medical centers in a-five-year period were reviewed. The patients were divided into subgroups according to the colonic localization of the tumor, appendect... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419624 Thu, 14 May 2009 07:04:45 +0100 2419624 http://www.medworm.com/index.php?rid=2419623&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv655868685275r18%2F Abstract  Brain abscesses represent organized foci of suppuration within the parenchyma. In this paper, we describe the case of a 3-month old girl with a large, complicated cerebral abscess. In addition, the course of treatment is presented. The patient’s recovery was excellent. The follow-up MRI showed only subtle porencephalic changes as the only parenchymal sequels, which may have been due to central nervous system (CNS) plasticity in infants. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0038-1Authors Afsoun Seddighi, Shahid Rajaie Hospital Department of Neurosurgery 1445744454 Qazvin IranAmir Saied Seddighi, Shohada Hospital Department of Neurosurgery 1445744454 Tehran Iran Journal Central European Journal of MedicineOnline ISSN 1644... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419623 Thu, 14 May 2009 07:04:45 +0100 2419623 http://www.medworm.com/index.php?rid=2419627&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F31xtm811u4mx80h5%2F We report a case of Type I dual left anterior descending coronary artery (LAD) giving rise to a pulmonary artery fistula via a short LAD branch, causing symptoms of typical angina. This rare coronary artery anomaly is importance to classify; it shows features of both intrinsic coronary artery anatomy anomaly and coronary drainage anomaly. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0052-3Authors Turgay Celik, Gulhane Military Medical Academy School of Medicine, Department of Cardiology 06018 Etlik-Ankara TurkeyM. Tarik Agac, Gulhane Military Medical Academy School of Medicine, Department of Cardiology 06018 Etlik-Ankara Turkey Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of M... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419627 Thu, 14 May 2009 07:04:43 +0100 2419627 http://www.medworm.com/index.php?rid=2419626&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb68500855wh6j42n%2F We report a case of a 36-year-old obese man who presented with newly onset diabetes mellitus type 2 and hypertension. The estimated value of glomerular filtration rate — 203.7 ml/min was associated with the patient being at high risk of developing progressive renal disease. In this case, in order to prevent nephropathy, the preferred therapy was a gradual bodyweight reduction. A low-calorie diet providing an 800 kcal/day deficit was recommended to the patient, as well as an increase in physical activity. After a total weight reduction of 50 kg (33% of initial bodyweight), the patient’s glomerular filtration, body mass index, and blood pressure normalized without any drug therapy. Glucose, blood pressure and lipid target levels can only be simultaneously achieved through body-weig... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419626 Thu, 14 May 2009 07:04:43 +0100 2419626 http://www.medworm.com/index.php?rid=2419625&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu345m5115p70kg56%2F Abstract  Adenocarcinomas of Ileal Duplication Cysts are an extremely rare occurrence, this is a case report and review of current literature as to the best management of this condition. Content Type Journal ArticleCategory Review ArticleDOI 10.2478/s11536-009-0046-1Authors Khalid Habib, Doncaster Royal Infirmary Department of Gastrointestinal Surgery Doncaster South Yorkshire DN2 5LT UKMansoor Khan, Doncaster Royal Infirmary Department of Gastrointestinal Surgery Doncaster South Yorkshire DN2 5LT UKA. Loraine Sheehan, Doncaster Royal Infirmary Department of Histopathology Doncaster South Yorkshire DN2 5LT UKOlujimi Coker, Doncaster Royal Infirmary Department of Gastrointestinal Surgery Doncaster South Yorkshire DN2 5LT UK Journal Central European Journal of Medicine... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2419625 Thu, 14 May 2009 07:04:43 +0100 2419625 http://www.medworm.com/index.php?rid=2252294&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnv56116131r22864%2F Abstract  A 3-year-old boy with a Nicolau Syndrome (NS) on the left side of the body and the limbs after benzathine penicilline injection is reported. To the authors’ best knowledge, this is the first report of hyperbaric oxygen used in the late treatment of NS preventing the progress of the necrosis and therefore limiting the amputation level. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-009-0022-9Authors Cemil Yildiz, Gülhane Military Medical Academy Department of Orthopedic and Traumatology 06018 Ankara TurkeyHüseyin Özkan, Gülhane Military Medical Academy Department of Orthopedic and Traumatology 06018 Ankara TurkeyHakan Ay, Gülhane Military Medical Academy Department of Undersea and Hyperbaric Medicine 06018 Ankara TurkeyYuksel Yurttaş, G... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2252294 Sun, 08 Mar 2009 09:49:08 +0100 2252294 http://www.medworm.com/index.php?rid=2252295&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe52m0lx33h042081%2F In conclusion, the present study indicates a significant role for reactive oxygen species (ROS) and their relation to liver and kidney dysfunction, and points to the therapeutic potential of LC in CDDP-induced liver and kidney toxicity. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0021-xAuthors Kerim Cayir, University of Atatürk Department of Internal Medicine, Faculty of Medicine 25700 Erzurum TurkeyAli Karadeniz, University of Atatürk Department of Physiology, Faculty of Veterinary Medicine 25700 Erzurum TurkeyAbdulkadir Yildirim, University of Atatürk Department of Biochemistry, Faculty of Medicine 25700 Erzurum TurkeyYildiray Kalkan, University of Atatürk Department of Histology and Embryology, Faculty of Medicine 25700 Erzurum TurkeyAkar Karak... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2252295 Sun, 08 Mar 2009 09:49:07 +0100 2252295 http://www.medworm.com/index.php?rid=2186873&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft11660v3583k5270%2F Abstract  High-residual platelet activity despite the dual antiplatelet treatment with aspirin and clopidogrel is associated with major adverse cardiac events, including stent thrombosis. Acute and subacute stent thrombosis is rare, but presents itself with serious complications including high mortality and morbidity rates. Light transmittance aggregometry with specific agonists — arachidonic acid and 5-adenosin diphosphate — is still considered a standard for the assessment of platelet reactivity, besides novel methods like vasodilator-stimulated phosphoprotein phosphorylation. In our case study, we report the coincidence of high-residual platelet activity with subacute stent thrombosis despite the recommended doses of antiplatelet agents — aspirin and clopidogrel. S... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186873 Thu, 12 Feb 2009 07:28:21 +0100 2186873 http://www.medworm.com/index.php?rid=2186872&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F39534253p8266207%2F We present a case of a woman who had caecal cancer with large contralateral inguinal lymphadenopathy. She underwent right hemicolectomy with excision of the inguinal lymph node. Histology confirmed adenocarcinoma of caecum metastasising to contralateral inguinal lymph nodes. Content Type Journal ArticleCategory Case ReportDOI 10.2478/s11536-008-0094-yAuthors Abdul Hakeem, Doncaster Royal Infirmary Senior House Officer DN2 5LT Doncaster UKMansoor Khan, Doncaster Royal Infirmary Specialist Registrar DN2 5LT Doncaster UKNeelam Dugar, Doncaster Royal Infirmary Consultant Radiologist DN2 5LT Doncaster UKMahariz Muzaffar, Doncaster Royal Infirmary Consultant Histopathologist DN2 5LT Doncaster UKJoy Robinson, Doncaster Royal Infirmary Consultant General and Colorectal Surgeon DN2 5LT Donca... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186872 Thu, 12 Feb 2009 07:28:21 +0100 2186872 http://www.medworm.com/index.php?rid=2186871&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb412246pt9353583%2F Abstract  The aim of this study was to analyse perinatal complications in woman with increased BMI at pregnancy term. Study included 23190 women who gave singleton birth during a 10-year period in our institution. Maternal databases were reviewed for pregnancy, labor and delivery complications and early maternal postpartum morbidity. Women with increased BMI at pregnancy term had a significantly higer incidence of postterm pregnancy, gestational diabetes, pregnancy-induced hypertension and third trimester hemorrhage, compared to normal weight women (p 0.000). Women with increased BMI had significantly more labor induction with prostaglandins (p 0.001 and 0.000) and elective caesarean (p 0.025 and 0.000). Also, overweight and obese women had higher incidence of operative del... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186871 Thu, 12 Feb 2009 07:28:21 +0100 2186871 http://www.medworm.com/index.php?rid=2186874&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa467n1u7w4217274%2F In conclusion, in this study characteristics positively associated with development of BCRL included occupation, infection, and increased BMI. Immediate reconstruction of the breast was not found as a risk factor for BCRL. However larger studies are needed, to further evaluate the effect of breast reconstruction on BCRL. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0010-0Authors Akif Serhat Gur, Medical Center Pittsburgh Magee-Womens Hospital of the University of Pittsburgh Pittsburgh PA 15213 USABulent Unal, Medical Center Pittsburgh Magee-Womens Hospital of the University of Pittsburgh Pittsburgh PA 15213 USAGretchen Ahrendt, Medical Center Pittsburgh Magee-Womens Hospital of the University of Pittsburgh Pittsburgh PA 15213 USAMichael L. Gimbel, Medi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186874 Thu, 12 Feb 2009 07:28:20 +0100 2186874 http://www.medworm.com/index.php?rid=2186875&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr1712026v8726060%2F Abstract  The aim of the present study is to evaluate the measurement of midnight salivary cortisol as a method of screening for Cushing’s syndrome (CS). Here we tested the performance of a highly sensitive electrochemiluminescence immunoassay (ECLIA) for midnight salivary cortisol measurement in an extensive clinical study (n=104). Three groups were investigated: 30 patients with CS, 34 with obesity and 40 healthy normal weight controls. All of them collected saliva samples at 24:00 h and urine samples over the same day (24 hour period). An electrochemiluminescence immunoassay was used to measure salivary cortisol. Mean midnight salivary cortisol in healthy volunteers, obese patients and patients with CS was 8.33 ± 3.62, 8.13 ± 4.47 and 33.11 ± 21.68 nmol/l, respectiv... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186875 Thu, 12 Feb 2009 07:28:19 +0100 2186875 http://www.medworm.com/index.php?rid=2186876&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F94p54646rg774362%2F In conclusion, teat tablets with sodium ibuprofen of the highest sorbitol content (79%) demonstrated the expected physicochemical parameters and high pharmaceutical availability. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-008-0087-xAuthors Aneta Berner-Strzelczyk, Medical University of Lodz Department of Applied Pharmacy 90-151 Lodz PolandJustyna Kołodziejska, Medical University of Lodz Department of Applied Pharmacy 90-151 Lodz PolandMagdalena Piechota-Urbañska, Medical University of Lodz Department of Applied Pharmacy 90-151 Lodz PolandMariusz Piechota, Boleslaw Szarecki University Hospital No. 5 in Lodz, Medical University of Lodz Department of Anaesthesiology and Intensive Care Unit 90-647 Lodz PolandMarian Mikołaj Zgoda, Medical University of Lodz... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186876 Thu, 12 Feb 2009 07:28:17 +0100 2186876 http://www.medworm.com/index.php?rid=2186877&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg16085563402u6l5%2F This study is aimed to examine the maintenance and utilisation of hearing aids given to clients attending government hospitals in Tshwane and to probe factors that impacted on the hearing aid fitting process, in order to contribute to the formation of service delivery guidelines. As most participants were embarrassed to wear their devices, results showed that there was a general consensus about the self-image and wearing of hearing aids. Furthermore, it was found that most government fitted hearing aids and accessories were poorly cared for and maintained. One of the factors which negatively influenced the utilisation and maintenance of hearing aids was finance. Participants could not afford to properly maintain and service their hearing instruments. Multilingualism also presented an... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186877 Thu, 12 Feb 2009 07:28:16 +0100 2186877 http://www.medworm.com/index.php?rid=2186879&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy611t417258320t3%2F In conclusion, rectal bleeding in the presence of constipation or diarrhea is the main sign for diagnosis of SRUS. This syndrome is usually misdiagnosed; it is frequently confused with inflammatory bowel disease (IBD) because the rectal macroscopic and microscopic lesions and true polyps of rectum are similar. We suggest that most of patients who are treating for IBD and true polyps without any response are suffering from SRUS. Regarding misdiagnosis between SRUS and IBD or rectal polyp, the exact prevalence of SRUS has been mistakenly underestimated. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0006-9Authors Saeed Derakhshani, Baharan Coloproctology Surgical Clinic 1516633115 Tehran IranMohsen Pakzad, Tehran University of Medical Sciences Faculty of... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186879 Thu, 12 Feb 2009 07:28:15 +0100 2186879 http://www.medworm.com/index.php?rid=2186878&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F05n033657k18p480%2F We describe the first case of uterine leiomyoma with lymphoid infiltration observed in a patient after chemotherapy for sigmoid cancer. We performed immunohistochemical analysis with a panel of antibodies to several markers. Detection of CD20, CD3, Ki67, CD68 and Epstein-Barr virus nuclear antigen assisted in the differential diagnosis and partial elucidation of the pathogenesis. In addition, we examined the lysosome-associated membrane proteins LAMP-1 and LAMP-2 for the first time in this lesion. Their expression was elevated, indicating enhanced autophagy, an indirect sign of degenerative changes in this benign tumor characterized by massive lymphoid infiltration. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0016-7Authors Veselin T. Belovejdov, Me... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186878 Thu, 12 Feb 2009 07:28:15 +0100 2186878 http://www.medworm.com/index.php?rid=2186880&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff665220744763524%2F Abstract  In the current study, we evaluated the dynamics of oxidative stress markers in patients with acute myocardial infarction (AMI) treated by primary percutaneous coronary intervention (PCI). Thirty consecutive patients with AMI with ST elevation were included. Plasma lipid peroxidation end product malondialdehyde (MDA) and total antioxidant capacity (TAC) in blood plasma were evaluated. Peripheral venous blood samples were obtained prior to reperfusion and at five time points after reperfusion. The control group consisted of 20 ischemic patients without acute coronary syndrome. TAC in the AMI group at admission was lower than in control patients (1.26 + 0.32 vs. 1.52 + 0.24 mmol/l). Within 1 h after reperfusion, in most cases, values significantly declined (1 min, 1.... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186880 Thu, 12 Feb 2009 07:28:14 +0100 2186880 http://www.medworm.com/index.php?rid=2186882&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe9331061w8q1x50r%2F In conclusion: 1) Aging decreases reactivity to respiratory alkalosis in elderly normotensives; 2) hyperventilation induces significant pressor changes frequently in essential hypertension, but rarely in secondary hypertension; 3) the significant pressor responses to hyperventilation reflect the daytime pressor profiles predicting the highest daily fluctuations of BP values. Content Type Journal ArticleCategory Research ArticleDOI 10.2478/s11536-009-0002-0Authors Fiorella Fontana, Università di Bologna Dipartimento di Medicina Interna, dell’Invecchiamento e delle Malattie Nefrologiche Ospedale S. Orsola 40138 Bologna ItalyPasquale Bernardi, Università di Bologna Dipartimento di Medicina Interna, dell’Invecchiamento e delle Malattie Nefrologiche Ospedale S. Orsola 40138 Bologn... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186882 Thu, 12 Feb 2009 07:28:12 +0100 2186882 http://www.medworm.com/index.php?rid=2186881&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe71459245w83231t%2F Abstract  Neurofibromatosis type I (NF1) is a hereditary multisystem disease involving the skin and nervous system. It is the most common form of autosomal dominant phakomatoses with 100% penetrance but wide phenotypic variability. The NF1 gene is located on chromosome 17q11.2 and encodes for a tumour suppressor protein. Because affected individuals have an increased risk of tumor formation, this disorder is classified as inherited cancer syndrome. The risk of malignancies in NF1 affected patients is estimated to be 5–15% higher than in the general population. We reviewed clinical aspects and genetic mechanisms of tumorigenesis in NF1 affected patients. Content Type Journal ArticleCategory Review ArticleDOI 10.2478/s11536-009-0013-xAuthors Maria Scalzone, Catholic Uni... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186881 Thu, 12 Feb 2009 07:28:12 +0100 2186881 http://www.medworm.com/index.php?rid=2186883&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmn0l6787776k751g%2F Abstract  Microarray, a miniaturized glass slide or membrane with immobilized DNA probes, is a powerful tool for the analysis of mutations, gene expression and sequencing. This technique requires chip (glass slide or membrane) fabrication, preparation of probes and labelled targets, hybridization and data analysis. Microarrays give the possibility to evaluate a wide spectrum of candidate genes, to simultaneously observe interaction of genes, to detect polymorphisms within genes and identify therapeutic targets. Coronary artery disease being a major cause of death, is a disorder influenced by either genetic or environmental factors. Microarray analysis of gene expression can be used to identify genes involved in disease progression and in disease reduction. Chips also allow ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186883 Thu, 12 Feb 2009 07:28:11 +0100 2186883 http://www.medworm.com/index.php?rid=2186884&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd24j2805515241k8%2F Content Type Journal ArticleCategory Letter to EditorDOI 10.2478/s11536-008-0089-8Authors Roberto Iacovelli, “Sapienza” University of Rome Department of Experimental Medicine, Oncology Unit B. 00161 Rome Italy Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 Journal Volume Volume 4 Journal Issue Volume 4, Number 1 / March, 2009 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=2186884 Thu, 12 Feb 2009 07:28:10 +0100 2186884