MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Central European Journal of Medicine' source. Wed, 08 Feb 2012 18:50:18 +0100 http://www.medworm.com/index.php?rid=5660732&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F89168357k5639256%2F Conclusion: Cavernous hemangiomas are rare lesions of the external auditory canal. In the morphological diagnosis, computed tomography of the temporal bones is the leading diagnostic procedure, along with otoendoscopy and endocranial magnetic resonance imaging which are important in evaluation of the spread of the lesion. Biopsy of vascular lesions is not recommended. Complete surgical excision of hemangioma of the external auditory canal is the therapy of choice with a minor risk of hearing impairment. Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.2478/s11536-011-0144-8Authors Ljiljana Vlaški, Clinical center of Vojvodina, University ENT Clinic, Hajduk Veljkova 1, Novi Sad, 21000 SerbiaDragan Dankuc, Clinical center of Vojvodina, University ENT Clinic, Hajduk... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5660732 Fri, 03 Feb 2012 07:21:52 +0100 5660732 http://www.medworm.com/index.php?rid=5610695&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh09538640x8k8371%2F Abstract  The paper presents a comparative study of selected recognition methods for the medical decision problem -acute abdominal pain diagnosis. We consider if it is worth using expert knowledge and learning set at the same time. The article shows two groups of decision tree approaches to the problem under consideration. The first does not use expert knowledge and generates classifier only on the basis of learning set. The second approach utilizes expert knowledge for specifying the decision tree structure and learning set for determining mode of decision making in each node based on Bayes decision theory. All classifiers are evaluated on the basis of computer experiments. Content Type Journal ArticleCategory Research ArticlePages 1-11DOI 10.2478/s11536-011-0142-xAuth... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5610695 Tue, 17 Jan 2012 07:07:14 +0100 5610695 http://www.medworm.com/index.php?rid=5610694&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frjq71911p43w8845%2F Conclusion  Atropine added to ET in patients who cannot achieve their 85% age-related HR is safe and well-tolerated, and improves the prognostic accuracy in patients with recent uncomplicated STEMI. The combination with atropine increases the utility and the cost-effectiveness of ET. Content Type Journal ArticleCategory Research ArticlePages 1-7DOI 10.2478/s11536-012-0001-4Authors Filippo M. Sarullo, Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, ItalyLuigi Americo, Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, ItalySalvatore Milia, Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo, ItalyIgnazio Brusca, Division of Cardiology, Buccheri La Ferla Fatebenefratelli Hospital, Palermo... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5610694 Tue, 17 Jan 2012 07:07:14 +0100 5610694 http://www.medworm.com/index.php?rid=5610697&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg640v3n4j3574510%2F Abstract  Children with malignancy present an important alteration of the immune system functionality caused by the illness itself and by the therapy they undergo. Therefore, they are at high risk of contracting vaccine-preventable diseases and of developing important complications. Vaccinations represent valid devices against these infections but this condition involves two main problems: are vaccines safe in these patients? Are vaccines effective in these patients? The aim of this review is to discuss the principles of vaccination management in children with cancer. Content Type Journal ArticleCategory Mini ReviewPages 1-5DOI 10.2478/s11536-011-0143-9Authors Andrea Battista, Pediatric Oncology Division, Catholic University, “A. Gemelli” Hospital, 00168 Rome, Ital... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5610697 Tue, 17 Jan 2012 07:07:12 +0100 5610697 http://www.medworm.com/index.php?rid=5610696&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq100x7k82152k182%2F Abstract  The purpose of this study was to investigate the relationship between weight status and recreational drug use in Korean adolescents. A total of 72,399 adolescent students (38,152 boys and 34,247 girls) from the middle first to high third grade participated in the 5th Korea Youth Risk Behaviour Web-based Survey (KYRBWS-V) project in 2009. They were assessed for body mass index (BMI) and recreational drug abuse. The associations between BMI and recreational drug use were examined using multivariable logistic regression analysis after adjusting for the covariate variables of age, smoking frequency and cigarette consumption, frequency of alcohol consumption and severe alcohol intoxication, amount of alcohol consumed, parents’ education level, economic status, sedent... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5610696 Tue, 17 Jan 2012 07:07:12 +0100 5610696 http://www.medworm.com/index.php?rid=5610698&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0g37783540657607%2F Abstract  The aim of the research was to evaluate the results of NDT-Bobath method in gait re-education of adult patients after ischemic stroke using normalized parameters of gait. The investigation group consisted of 60 patients, all sufferers of an ischemic stroke, and participated in a rehabilitation program: 10 sessions of NDT-Bobath therapy through 2 weeks (ten days of the therapy). Normalized parameters of gait were calculated based on anthropometric measures of patients and their gait parameters (gait velocity, cadence and stride length) measured in every patient on admission (before the therapy) and after the last session of the therapy to assess rehabilitation effects. Results among patients involved in the research were as follows: •  in normal... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5610698 Tue, 17 Jan 2012 07:07:11 +0100 5610698 http://www.medworm.com/index.php?rid=5583855&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F51q541l7l346q1h3%2F Conclusion  Authors recommend using mechanical cleaning in cases of mildly eroded ossicles. In cases of badly eroded ossicles authors recommend to either apply a combination of mechanical and autoclaving treatment. The study proved that 4 minutes of autoclaving at 134°C after mechanical cleaning provides safe bone autografts. Content Type Journal ArticleCategory Research ArticlePages 1-4DOI 10.2478/s11536-011-0140-zAuthors Lukas Skoloudik, Department of Otorhinolaryngology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove 1, 500 38 Prague, Czech RepublicJan Vokurka, Department of Otorhinolaryngology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove 1, 500 38 Prague, Czech RepublicEva Simakova, Department of... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5583855 Wed, 11 Jan 2012 17:53:19 +0100 5583855 http://www.medworm.com/index.php?rid=5583856&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl770045315837802%2F Conclusion  cesarean delivery increases infants’ respiratory distress syndrome in late preterm and term infants Content Type Journal ArticleCategory Research ArticlePages 1-5DOI 10.2478/s11536-011-0139-5Authors Małgorzata Baumert, Department of Neonatology Silesian Medical University, ul. Medyków 14, 40-752 Katowice, PolandMałgorzata Fiala, Department of Neonatology Silesian Medical University, ul. Medyków 14, 40-752 Katowice, PolandZofia Walencka, Department of Neonatology Silesian Medical University, ul. Medyków 14, 40-752 Katowice, PolandMagdalena Paprotny, Department of Neonatology Silesian Medical University, ul. Medyków 14, 40-752 Katowice, PolandKinga Sypniewska, Department of Neonatology Silesian Medical University, ul. Medyków 14, 40-752 Katowice, Polan... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5583856 Wed, 11 Jan 2012 17:53:16 +0100 5583856 http://www.medworm.com/index.php?rid=5583857&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk2l772447024g175%2F Conclusion  Contemporary medical science could show improved outcomes not only by fragmenting into smaller specialized pieces, but also associating into bigger units, especially in the case of psychiatry. However, more exhaustive research should be provided to confirm such necessity Content Type Journal ArticleCategory Case ReportPages 1-6DOI 10.2478/s11536-011-0141-yAuthors Rytis Leonavičius, Department of Psychiatry of Medical Academy, Lithuanian University of Health Sciences, Eiveniu st. 2, Kaunas, LT-50009 Republic of LithuaniaVirginija Adomaitienė, Department of Psychiatry of Medical Academy, Lithuanian University of Health Sciences, Eiveniu st. 2, Kaunas, LT-50009 Republic of Lithuania Journal Central European Journal of MedicineOnline ISSN 1644-3640Pr... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5583857 Wed, 11 Jan 2012 06:57:45 +0100 5583857 http://www.medworm.com/index.php?rid=5583858&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn40r6227j8153566%2F Abstract  The implementation of new markers of bacterial infection into clinical practice is hindered by their costs. We assessed the potential use of the neutrophil to lymphocyte count ratio (NLCR) to discriminate between bacterial and viral infections. NLCR was evaluated in 45 patients with bacterial infections: 24 patients with viral infections and 18 healthy adults. The medians of NLCR were 11.73 in bacterial infections, 2.86 in viral infections and 1.86 in controls. The NLCR cut-off value of 6.2 exhibited a sensitivity value of 0.91 and a specificity value of 0.96 for bacterial infection. These results suggest a diagnostic potential for NLCR. Content Type Journal ArticleCategory Research ArticlePages 1-4DOI 10.2478/s11536-012-0002-3Authors Michal Holub, Departmen... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5583858 Sat, 07 Jan 2012 16:53:38 +0100 5583858 http://www.medworm.com/index.php?rid=5583860&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F55763r734x0x8117%2F Abstract  The aim of this study was to describe the musculoskeletal manifestations of mucopolysaccharidosis VI and to assess the effectiveness of enzyme replacement therapy (ERT) with recombinant human arylsulfatase B on the bone and joint involvement in a patient with a severe phenotype of the disease. Before the initiation of ERT, the patient presented with significant range of motion (ROM) limitations at multiple joints. Flexion contractures were noticeable in all joints. After 48 weeks of ERT, improvement in active and passive shoulder flexion, as well as passive elbow and wrist flexion, was noticed. ROM improvements were reflected in patient’s enhanced self-care. Content Type Journal ArticleCategory Case ReportPages 1-9DOI 10.2478/s11536-012-0003-2Authors Jolan... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5583860 Sat, 07 Jan 2012 16:53:35 +0100 5583860 http://www.medworm.com/index.php?rid=5583859&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm80tn22857k181r6%2F Abstract  Verrucous carcinoma is a slow growing, well demarcated, exophytic variant of squamosus cell carcinoma with a characteristic verrucous presentation. It is a rare tumour and in 75% of cases it is localised in the oral cavity, and sporadically within the tongue. HPV infection is identified in 40% of patients. Good prognosis is characteristic for this tumour, since the 5-year survival is 93%. The authors describe a case of verrucous carcinoma localised in the tongue of a 62-year old patient. The clinical course, diagnostics and proposed treatment was described and discussed with the existing literature data. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.2478/s11536-011-0137-7Authors Jadwiga Waskowska, Department of Oral Surgery in Bytom, Medical... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5583859 Sat, 07 Jan 2012 16:53:35 +0100 5583859 http://www.medworm.com/index.php?rid=5572952&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq005v7467516q367%2F Conclusions  Dehiscence risk coefficient measurement six weeks after delivery allows for precise quantitative description of the CS scar. Urgent CS has a higher risk for a severe scar defect. Content Type Journal ArticleCategory Research ArticlePages 1-6DOI 10.2478/s11536-011-0134-xAuthors Erik Dosedla, Slovak Medical University, Faculty of Medicine, Bratislava, III. Department of Gynecology and Obstetrics, 1st Private Hospital Košice-Šaca Inc., Košice-Šaca, Slovak RepublicTomáš Kvasnička, First Faculty of Medicine and General Teaching Hospital, Thrombosis Centre of Institute of Clinical Biochemistry and Laboratory Diagnostics, Charles University, Prague, U Nemocnice 2, 128 08 Praha 2, Czech RepublicPavel Calda, First Faculty of Medicine and General Teaching Ho... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5572952 Thu, 05 Jan 2012 06:52:36 +0100 5572952 http://www.medworm.com/index.php?rid=5572951&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F921246vx1324720t%2F Abstract  The authors present the case of a girl with Frasier syndrome that was diagnosed at the age of 4 years. At 3.5 years, she was diagnosed a steroid-resistant nephrotic syndrome associated with focal segmental glomerulosclerosis. The girl presented with female phenotype and male genotype (46XY) as well with gonadal dysgenesis. Genetic analysis confirmed the +2T>C mutation in the intron 9 of the WT1 gene. She developed end-stage renal disease at 14 years, culminating in renal transplantation. The liver biopsy revealed a post-transplantation lymph-proliferative disease. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.2478/s11536-011-0135-9Authors Biljana Miloševic, Department of Nephrology, Institute for Child and Youth Health Care of Vojvodina,... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5572951 Thu, 05 Jan 2012 06:52:36 +0100 5572951 http://www.medworm.com/index.php?rid=5561651&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F34n02041j37x7182%2F Abstract  Informed consent in today’s medical practice has become a cornerstone and a routine ethical component playing a major role in forming a therapeutic alliance with the patient. The present study sought to analyse the effectiveness of the consent forms and the consenting process in Otorhinolaryngology. This three month questionnaire-based study covered varying operations which ranged from tonsillectomies, grommet insertions to pharyngeal pouch stapling. Twenty-nine percent of consent forms were signed on the day of the operation. Of the patients who received leaflets (51%) during the process of informed consent, a majority (88%) found it useful. The respondents were satisfied with the explanation of the procedure, benefits and complications (70–74%). Majority kep... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5561651 Fri, 30 Dec 2011 07:07:47 +0100 5561651 http://www.medworm.com/index.php?rid=5561652&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftwpp518tv06350t3%2F Conclusions  Captopril and mercaptoethanol are potent free radical scavengers, reacting rapidly with ·OH, whereas cysteamine acts preferentially as a chelator of iron and in this way prevents the formation of ·OH. Content Type Journal ArticleCategory Research ArticlePages 1-5DOI 10.2478/s11536-011-0132-zAuthors Lubomir Petrov, Institute of Neurobiology, Bulgarian Academy of Sciences, 23, Acad. G. Bonchev str, 1113 Sofia, BulgariaMila Atanassova, Institute of Neurobiology, Bulgarian Academy of Sciences, 23, Acad. G. Bonchev str, 1113 Sofia, BulgariaAlbena Alexandrova, Institute of Neurobiology, Bulgarian Academy of Sciences, 23, Acad. G. Bonchev str, 1113 Sofia, Bulgaria Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Sou... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5561652 Fri, 30 Dec 2011 07:07:46 +0100 5561652 http://www.medworm.com/index.php?rid=5561653&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj368163jk2x15367%2F We present a rare case of acute abdomen due to rupture of ovarian metastatic malignant melanoma seven years after removal of a primary cutaneous malignant melanoma lesion, followed by reexcision of the cicatrix and axillary dissection (Clark III, Breslow IV), one year after osteoplastic parietal craniotomy for removal of recidiv metastatic lesions, and excision of the cutaneous malignant melanoma lesion on the upper leg were performed. During laparotomy because of acute abdomen, 4 L of free liquid (blood and ascites) were evacuated. The right adnexal mass was loose tumor, size 110x75 mm, with rupture on the posterior wall and hemorrhage. Unilateral adnexectomy was performed. Pathohystologic evaluation revealed tumor cells with eosinophilic, clear cytoplasm, intracytoplasmatic melanot... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5561653 Fri, 30 Dec 2011 07:07:45 +0100 5561653 http://www.medworm.com/index.php?rid=5516198&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx31137k361835644%2F We present a 42-year-old female admitted for a 4 month history of increasing pelvic discomfort and pain. Clinical examination revealed a large tumor obstructing the vagina. Tumor markers (CA 125, CEA, AFP and CA 19-9), white blood cells and biochemical tests were all within the normal limits. Pelvic ultrasound and magnetic resonance imaging scan confirmed the presence of a large retroperitoneal/pelvic mass. The tumor was surgically excised and pathohistologically diagnosed as a well differentiated leiomyosarcoma, staged IB. Six years after surgery the patient is well and disease free. Content Type Journal ArticleCategory Case reportPages 1-4DOI 10.2478/s11536-011-0128-8Authors Milan Terzic, Department of Gynaecology and Obstetrics, School of Medicine, University of Belgrade, Vis... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5516198 Fri, 16 Dec 2011 16:56:14 +0100 5516198 http://www.medworm.com/index.php?rid=5516199&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe231101526pm6180%2F Abstract  Non-invasive measurement of intracranial pressure (ICP) reduces the complications and cost for both patient and health care systems. Improvement of non-invasive methods has led to development of systems for reproducing continuous, real-time non-invasive ICP signals. So far, non-invasive methods have been tailored for the patients with head trauma. We have used Schmidt’s auto-adaptive method to assess the accuracy of this method for patients after surgery for supratentorial brain tumors. Data from forty patients with the diagnosis of brain tumor operated from 2008 to 2010 were used to estimate the accuracy of Schmidt’s method in our patients. We obtained the model parameters from 30 recordings. We determined the ICP wave form for the remaining patients by both ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5516199 Fri, 16 Dec 2011 16:56:13 +0100 5516199 http://www.medworm.com/index.php?rid=5495752&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2q83880252381018%2F Abstract  The aim of this study was to develop and validate a linguistically and culturally appropriate version of the Edinburgh Postnatal Depression Scale (EPDS) for use with women attending antenatal care in Romania. We translated and tested a Romanian version of the EPDS (EPDS-R) in four hospitals in three Romanian cities: Cluj-Napoca, Satu Mare, and Sighetu-Marmatiei. The study population included third-trimester women attending antenatal clinics (n=418); 364 subjects were included in the analytic sample. We used the Center for Epidemiologic Studies Depression Scale (CES-D) as a “gold standard”. We assessed reliability, validity, and conducted sensitivity analysis to establish an EPDS-R cutpoint. We found that reliability was robust (α=0.89) and there was a signifi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5495752 Sat, 10 Dec 2011 06:42:17 +0100 5495752 http://www.medworm.com/index.php?rid=5495754&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh2t807354634h29x%2F Abstract  The purpose of this study was to evaluate self-rated musculoskeletal complaints and their association with computer use time in the adolescent population in Lithuania. The cross-sectional study done in 2008–2009 in Lithuania. 1806 students aged 13–18 years from randomly selected schools were questioned (response rate 95.8%). Logistic regression analysis results show that musculoskeletal complaints in adolescence are associated with duration of computer use as related to age and gender. Compared with adolescents using computer <2 hours daily, a statistically significant probability of experiencing back pain was determined for younger boys and girls groups (13–15 years) who reported working on a computer >4 hours (OR=2.36 and OR=2.50, respectively) in ol... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5495754 Sat, 10 Dec 2011 06:42:16 +0100 5495754 http://www.medworm.com/index.php?rid=5495753&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr1m3x86402l7k916%2F Abstract  Oral health-related quality of life (OHRQoL) is multifaceted and involves many factors. One of them is the use of dental implants. It was the aim of our study to assess whether implant therapy might improve OHRQoL. We consulted patients with at least one Astra Tech implant. Each patient completed oral health questionnaires, which were then statistically evaluated using the Wilcoxon signed-ranks test and Analysis of Covariance from a functional and aesthetic point of view. Differential response on individual scales was assessed using multivariate approach. All twelve marginal Wilcoxon tests showed an overall improvement in OHQoL (α = 0.05). On the aesthetic scale, OHRQoL was found to be associated with marital status, aesthetic reasons for undergoing surgery and n... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5495753 Sat, 10 Dec 2011 06:42:16 +0100 5495753 http://www.medworm.com/index.php?rid=5488228&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvgu3962047401850%2F Abstract  Erysipelas is a bacterial cellulitis usually associated with Streptococcal infection. It may appear as a complication following mastectomy and radiotherapy for breast cancer. The study involved 17 cases of erysipelas of the upper limbs with a median age of 62 years. Here we described the clinical, therapeutic and evolutionary aspects of erysipelas. Our results indicated that the erysipelas appeared with an average of 9 years after mastectomy and was recurrent in three patients (17.64%). It is associated with obesity in 42% and arterial hypertension in 52.9% of patients with breast cancer after radical mastectomy. Breast cancer patients in advance stages of disease at presentation (T2+ T3) are significantly more subject to erysipelas in comparison to those patients... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5488228 Tue, 06 Dec 2011 17:00:41 +0100 5488228 http://www.medworm.com/index.php?rid=5432689&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd431058uu86l3u65%2F Conclusions  Patients with tuberculosis demonstrated good knowledge of their disease. Patients with higher socioeconomic status and education level were more knowledgeable about their disease. Content Type Journal ArticleCategory Research ArticlePages 1-9DOI 10.2478/s11536-011-0124-zAuthors Miroslav Ilic, Policlinic department, Institut for pulmonary diseases of Vojvodina, Institutski put, 421204 Sremska Kamenica, SerbiaVesna Kuruc, Policlinic department, Institut for pulmonary diseases of Vojvodina, Institutski put, 421204 Sremska Kamenica, SerbiaSlobodan Pavlovic, Clinic for tuberculosis, Institut for pulmonary diseases of Vojvodina, Institutski put, 421204 Sremska Kamenica, SerbiaIvan Kopitovic, Urgent Pulmonology Clinic, Institut for pulmonary diseases of Vojvodin... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5432689 Fri, 18 Nov 2011 06:57:57 +0100 5432689 http://www.medworm.com/index.php?rid=5432690&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc2n70h0002x36177%2F Abstract  Patients suffer differential prescribing behavior as a function of their socioeconomic status. The current study was conducted in a qualitative and two observational phases in Lahore metropolitan area to investigate physician’s perspectives of patients’ socioeconomic status and the important indicators influencing prescribing behavior. Semi-structured interviews were conducted with physicians (N=20) from 2 hospitals, 2 diabetes care centers and 2 private clinics and scripts were analyzed for socioeconomic indicators. In the second phase, the opinions of a panel of prescribers (N=43) on the influence socioeconomic indicators on prescribing behavior were elicited. In the third phase a bipolar 5-point Likert rating scale was used to elicit the importance of indica... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5432690 Fri, 18 Nov 2011 06:57:56 +0100 5432690 http://www.medworm.com/index.php?rid=5432692&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb47k6310734m131v%2F Abstract  The principle of symmetry-asymmetry is widely presented in the structural and functional organization of the nonliving and living nature. One of the most complex manifestations of this principle is the left-right asymmetry of the human brain. The present review summarizes previous and contemporary literary data regarding the role of brain asymmetry in neuroimmunomodulation. Some handedness-related peculiarities are outlined additionally. Brain asymmetry is considered to be imprinted in the formation and regulation of the individual’s responses and relationships at an immunological level with the external and internal environment. The assumptions that the hemispheres modulate immune response in an asymmetric manner have been confirmed in experiments on animals. S... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5432692 Fri, 18 Nov 2011 06:57:55 +0100 5432692 http://www.medworm.com/index.php?rid=5432691&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu749417122654706%2F Abstract  The study involved 27 lateral cervical schwannomas surgically treated in the last 40 years utilizing either partial or total resection. The study aims to compare the results of total and partial resection of spinal lateral schwannoma and to assess the values of partial resection of large lateral cervical schwannomas. We performed a retrospective analysis of 27 patients operated for lateral cervical schwannomas in the period 1971–2010, out of which 11 had partial resection. The average follow-up of the patients was 136.4 months, comparing pre- and postoperative clinical picture, time to relapse, dynamics of yearly growth of schwannomas, and the need for re-resection. The average period of preoperative complaint in lateral cervical schwannomas was 19.6 months. Uni... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5432691 Fri, 18 Nov 2011 06:57:55 +0100 5432691 http://www.medworm.com/index.php?rid=5423462&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm5638x50682h186l%2F In conclusion, our results suggest that patterns of WCST activation and deactivation vary between patients with schizophrenia. Among the network of involved brain structures, right temporal cortex and thalami appear to play the major role. Content Type Journal ArticleCategory Research ArticlePages 1-8DOI 10.2478/s11536-011-0117-yAuthors Anna Nocuń, Department of Nuclear Medicine, Medical University of Lublin, 20-954 Lublin, PolandJustyna Pawęzka, Department of Psychiatry, Medical University of Lublin, 20-954 Lublin, PolandBeata Chrapko, Department of Nuclear Medicine, Medical University of Lublin, 20-954 Lublin, PolandKinga Szymona, Department of Psychiatry, Medical University of Lublin, 20-954 Lublin, PolandAgata Smoleń, Department of Mathematics and Biostatistics, Medical Uni... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5423462 Wed, 16 Nov 2011 06:47:34 +0100 5423462 http://www.medworm.com/index.php?rid=5423464&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl8r8872630920702%2F Abstract  In this paper a pattern recognition approach to classifying quantitative structure-property relationships (QSPR) of the CYP2C19 isoform is presented. QSPR is a correlative computer modelling of the properties of chemical molecules and is widely used in cheminformatics and the pharmaceutical industry. Predicting whether or not a particular chemical will be metabolized by 2C19 is of primary importance to the pharmaceutical industry. This task poses certain challenges. First of all analyzed data are characterized by a significant biological noise. Additionally the training set is unbalanced, with objects from negative class outnumbering the positives four times. Presented solution deals with those problems, additionally incorporating a throughout feature selection fo... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5423464 Wed, 16 Nov 2011 06:47:33 +0100 5423464 http://www.medworm.com/index.php?rid=5423463&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv8h73p541552m085%2F Conclusions. A few but significant differential predictors were found distinguishing Panic-agoraphobic patients, social phobics and those suffering from GAD from one another. There are only few specific predictive risk factors evident as essentially differing within anxiety syndromes. Content Type Journal ArticleCategory Research ArticlePages 1-6DOI 10.2478/s11536-011-0119-9Authors Elek Dinya, Department of Medical Informatics and Education, Semmelweis University, H-1086 Budapest VIII, Üllői út 78/b, HungaryJanos Csorba, Bárczi Gusztáv Faculty of Special Needs Education, Department of Special Needs Pathology, Eötvös Lóránd University of Sciences, Budapest, H-1097 Ecseri út 3., HungaryZsófia Grósz, Fodor József Department of National Public Health, Semmelweis Universit... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5423463 Wed, 16 Nov 2011 06:47:33 +0100 5423463 http://www.medworm.com/index.php?rid=5423465&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkw5270842178418v%2F We present a case of a 24-yearold woman with a subperiosteal diaphyseal angiosarcoma originating from the femoral bone and metastatic to the lung at the time of diagnosis. The clinical, histological and radiological features of this extremely rare lesion are presented. Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.2478/s11536-011-0118-xAuthors Evi Vassalou, Department of Medical Imaging, University Hospital, Heraklion, 711 10 GreeceEvangelos Perdikakis, Department of Medical Imaging, University Hospital, Heraklion, 711 10 GreeceElpida Giannikaki, Department of Pathology, University Hospital, Heraklion, 711 10 GreeceDimitris Mavroudis, Department of Medical Oncology, University Hospital, Heraklion, 711 10 GreecePavlos Katonis, Department of Othopaedics, University... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5423465 Wed, 16 Nov 2011 06:47:32 +0100 5423465 http://www.medworm.com/index.php?rid=5389409&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa560j5k80137871v%2F Abstract  The prevalence of insomnia is greater in end-stage renal disease. The aim of our study was to determine the frequency of insomnia and subclinical insomnia in patients with various dialysis therapy and kidney transplant recipients, in order to assess the severity of insomnia and examine whether there is a difference in severity among groups. In cross-sectional study, we evaluated 120 patients with terminal renal failure. Based on therapy, patients were divided into four groups: hemodiafiltration, standard bicarbonate dialysis, peritoneal dialysis and kidney transplant recipients. The severity of insomnia was evaluated through the use of the Insomnia Severity Index (ISI). Most patients who reported any kind of insomnia problems with ISI were on conventional dialysis... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5389409 Sat, 05 Nov 2011 17:11:06 +0100 5389409 http://www.medworm.com/index.php?rid=5389410&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj07u3k5336663677%2F Conclusions  The non-severe degenerative AS-population had higher 10 years risk of cardiovascular death based on SCORE system than severe AS-patients, what was probably resulted from arterial hypertension. Content Type Journal ArticleCategory Research ArticlePages 1-5DOI 10.2478/s11536-011-0114-1Authors Bogdan Jegier, Department of Cardiac Surgery, Chair of Cardiology and Cardiac Surgery, Medical University of Lodz, 91-425 Lodz, PolandRyszard Jaszewski, Department of Cardiac Surgery, Chair of Cardiology and Cardiac Surgery, Medical University of Lodz, 91-425 Lodz, PolandMalgorzata Lelonek, Department of Cardiology, Chair of Cardiology and Cardiac Surgery, Medical University of Lodz, 91-425 Lodz, Poland Journal Central European Journal of MedicineOnline ISSN 164... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5389410 Thu, 03 Nov 2011 16:53:55 +0100 5389410 http://www.medworm.com/index.php?rid=5389411&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj1293310u61432v6%2F Abstract Material and methods  Analysis covered a retrospective group of 334 neonates (194 male neonates and 140 female neonates), reported to the Polish Registry of Congenital Malformations (PRCM), between 2001–2005. Results  The frequency of the occurrence of the urinary tract anomalies was 1.7/1000 in live newborns. No significant differences have been found between the boys and girls, regarding the duration of the pregnancy, birth weight and the occurrence of the individual urinary tract anomalies. The anomalies of the renal pelvis and ureter (0.74/1000 in live newborns) were most frequent. It has been found that 9% of their families were diagnosed with urinary tract anomalies; occurring more often in girls’ families. We also observed other organs... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5389411 Wed, 02 Nov 2011 16:59:44 +0100 5389411 http://www.medworm.com/index.php?rid=5363231&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa716236m5080w507%2F Abstract  The aim of this study was to determine influence of selected lifestyle factors on kidney cancer. The study brings data from two centres of international multicentric hospital-based analytical observational case-control studies. Data were obtained from a group of 300 patients newly diagnosed with kidney cancer (ICD-O-2 code C64) and 335 controls from two centres in the Czech Republic. Results showed that smoking increased OR to 1.09 (95% CI 0.77–1.55) and 1.06 (95% CI 0.73–1.52), but the results were not statistically significant. Obesity (BMI⩾30) created adjusted OR 1.71 (95% CI 1.11–2.66) and 1.44 (95% CI 0.91–2.28), showing a minor, statistically insignificant, effect of obesity on the development of kidney cancer. For hypertension, adjusted OR was 1.7... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5363231 Fri, 28 Oct 2011 17:22:23 +0100 5363231 http://www.medworm.com/index.php?rid=5363232&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2823167113017g62%2F We present herein a patient with the double simultaneous arterial thromboses as the manifestation of thrombophilia (heterozygous for methylenetetrahydrofolate-reductase (MTHFR) C677T gene mutation). There was no patent foramen ovale suspected upon the patient’s admittance to hospital. To the best of our knowledge there have been no similar cases presented to date. Content Type Journal ArticleCategory Case reportPages 1-4DOI 10.2478/s11536-011-0110-5Authors Mirjana Krotin, Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000 Belgrade, SerbiaMarija Zdravkovic, Department of Cardiology, University Clinical Hospital Center Bezanijska Kosa, 11000 Belgrade, SerbiaDanica Popovic-Lisulov, Department of Cardiology, University Clinical Hospital Center Beza... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5363232 Fri, 28 Oct 2011 17:22:22 +0100 5363232 http://www.medworm.com/index.php?rid=5363233&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn632511086r47831%2F We present three different cases of patients with papilledema: one case with a primary tumour of the optic nerve, and two cases with secondary involvement of the optic nerve (breast carcinoma and non-Hodgkin lymphoma). The visual acuity varies from sudden, painless, decrease of vision, to blurred vision and proptosis on the affected eye. A characteristic ophthalmoscopic examination shows a swollen optic disc and promonence with tortuosity of blood vessels. A fluorescein angiography shows dilated capillaries of the optic disc with leakage in the early phase and diffuse hyperfluorescence during the late phase. A ultrasonography B-scan of the affected eye shows prominent optic nerves with widened optic nerve sheath. An exhaustive history and complete ophthalmological examination are ess... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5363233 Fri, 28 Oct 2011 06:06:13 +0100 5363233 http://www.medworm.com/index.php?rid=5363234&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm264x2m2305lt581%2F Abstract  Quality assurance becomes an increasingly important part of clinical medicine and of the field of endoscopy. Endoscopic sphincterotomy is associated with a fairly high complication rate. We aimed to assess our quality of sphincterotomy for benchmarking by using a prospective electronic database registry, and to identify potential risk factors for post-interventional complications. Over 2 years, 471 sphincterotomies were performed in a single tertiary referral centre. Patient- and procedure-related variables were prospectively recorded with the support of a multi-centre international sphincterotomy registry. Multivariate analysis was performed. The overall post-interventional complication rate was 9.3%. Pancreatitis happened in 5.5%, bleeding in 2.1%, perforation i... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5363234 Fri, 28 Oct 2011 06:06:11 +0100 5363234 http://www.medworm.com/index.php?rid=5337687&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc650481426t129uq%2F We present our experiences with 4 pediatric cases of allergic contact dermatitis induced by henna tattooing and give a brief review of the literature. The agent responsible for contact allergy was proven to be PPD in 3 patients, and in one patch testing revealed positive reactions to PPD and benzocaine, as well as to wool alcohols, nickel sulphate and potassium dichromate, to previously used hair dye—all being of clinical relevance. Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.2478/s11536-011-0106-1Authors Sonja Prcic, Pediatric Clinic, Institute of Child and Youth Health Care of Vojvodina, Hajduk Veljkova 10, 21000 Novi Sad, SerbiaAleksandra Matic, Pediatric Clinic, Institute of Child and Youth Health Care of Vojvodina, Hajduk Veljkova 10, 21000 Novi Sad, Se... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5337687 Wed, 19 Oct 2011 05:55:59 +0100 5337687 http://www.medworm.com/index.php?rid=5337688&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F41j0793j6w64753t%2F Abstract  Only a few studies reveal immunological changes in breast milk after the intake of probiotic and none focus on secretory IgA (sIgA). The aim our report was to investigate the levels of sIgA in human breast milk and stools before and after 4 weeks of probiotic intake in a patient with ulcerative colitis (UC) and a control. The study included 2 lactating women: 1 with UC and 1 control. Both received daily 3.75 billion viable Lactobacillus bulgaricus for 28 days. SIgA was measured in breast milk and stools before and after the probiotic intake. The concentration of sIgA in breast milk before the probiotic intake in UC was 408.5 vs 137.4 µg/ml in contol. Fecal sIgA in UC was 420 vs 274 µg/ml in control. After 28 days of probiotic intake there was a decrease in breast... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5337688 Wed, 19 Oct 2011 05:55:58 +0100 5337688 http://www.medworm.com/index.php?rid=5324852&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff517025713n166u5%2F Conclusion  We found that the PACT device did not have a sufficient antimicrobial effect in vitro. In contrast, the disinfection agents containing chlorhexidini digluconas were effective and may be a safe, non-specific alternative to antibiotic treatments. Promising results from some clinical studies can have different mechanism of action as disinfection. Content Type Journal ArticleCategory Research articlePages 1-6DOI 10.2478/s11536-011-0107-0Authors Zbyněk Matějka, Clinic of Child Surgery Clinical Centre, 18000 Nis, SerbiaVáclava Adámková, Clinic of Child Surgery Clinical Centre, 18000 Nis, SerbiaRoman Šmucler, University School of Medicine, 18000 Nis, SerbiaJana Svobodová, Clinic of Child Surgery Clinical Centre, 18000 Nis, SerbiaHana Hubálková, Universi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5324852 Sat, 15 Oct 2011 05:52:18 +0100 5324852 http://www.medworm.com/index.php?rid=5324851&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy7v1154556v57286%2F We present a case of hiccups associated with intra-articular Diprospan (Betamethasone Sodium Phosphate) administration. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.2478/s11536-011-0105-2Authors Boris Solun, Hasharon Hospital, Rabin Medical Center, Petah Tikva, 49100 IsraelYakov Ori, Sackler Faculty of Medicine, Tel-Aviv University, Ramat Aviv, 69978 Israel Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5324851 Sat, 15 Oct 2011 05:52:18 +0100 5324851 http://www.medworm.com/index.php?rid=5324854&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn62117q165494452%2F Abstract  The patient presented is a 44-year-old female treated for cavitary changes in the lung apexes. Due to suspected tuberculosis, treatment began with anti-tuberculosis (AT) drugs, despite negative sputum smears for acid-fast bacilli. During hospitalization, the patient was febrile (up to 38°C), hypotensive, extremely cachectic (32 kg), had a dry cough, increased nitrogen products, hypokalemia and anemia. Because of poor response to the applied AT therapy, bronchoscopic tests were repeated and spores of aspergillus fungus were discovered in the pathohistological findings of transbronchial lung biopsy. The appropriate treatment with amphotericin B and voriconazole was initiated. A psychiatric opinion was requested because we suspected that the patient suffered from th... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5324854 Sat, 15 Oct 2011 05:52:17 +0100 5324854 http://www.medworm.com/index.php?rid=5324853&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F742tk6425gk12526%2F We describe improved nonoperative treatment of patient with posttraumatic pancreatic pseudocyst with somatostatin analogue. A 9-year-old girl was admitted to our hospital after blunt abdominal trauma with handlebar. Three weeks after abdominal trauma, pancreatic pseudocyst developed. Nonoperative treatment of posttraumatic pancreatic pseudocyst (the largest dimensions 70 × 55 × 65 mm) with somatostatin analogue, octreotide acetate, was applied for the next 52 days. The patient was followed up for 24 months after the discontinuation of octreotide and there were no recurrence of pancreatic pseudocyst. Somatostatin analogue could be usefull in the nonoperative treatment of posttraumatic pancreatic pseudocysts in children. Content Type Journal ArticleCategory Case reportPages 1-4D... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5324853 Sat, 15 Oct 2011 05:52:17 +0100 5324853 http://www.medworm.com/index.php?rid=5316686&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmg3169vl85575428%2F Abstract  Intussusception in adults is a very rare entity that occurs in only 5% of all intestinal obstructions. Most often, in 66% of cases, intussusception is localized to the small intestine, while jejunogastric intussusception is very rare and occurs in 0,1%. Since the first case of jejunogastric intussusception after gastrojejunostomy was described by Bozzi in 1914, fewer than 200 isolated cases of postoperative intussusception after gastric surgery have been reported. Here we present a case of anterograde jejunogastric intussusception, 15 years after radical subtotal gastrectomy with Billroth II anastomosis in a 71-year-old man. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.2478/s11536-011-0103-4Authors Dragan S. Canovic, Department of Ge... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5316686 Sat, 08 Oct 2011 05:52:25 +0100 5316686 http://www.medworm.com/index.php?rid=5316687&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv3lp02l503183676%2F We present a case involving a patient with normal liver function tests from whom we removed a giant common bile duct stone measuring 7.5 centimeters × 4.0 centimeters × 4.0 centimeters. Postoperatively recurrent common bile duct stones were observed and removed with an endoscopic maneuver in the three-year follow-up period. Recurrent bile duct stones are frequently reported in the case of large size of stones or multiple stones. Surgical treatment may then be considered as a first-line treatment in cases of recurrent common bile duct stones. When an endoscopic or surgical approach is used for the treatment of giant common bile duct stones, careful observation is of the utmost importance and treatment innovations may be necessary. Content Type Journal ArticleCategory Case Report... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5316687 Sat, 08 Oct 2011 05:52:23 +0100 5316687 http://www.medworm.com/index.php?rid=5251807&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp51hm3j179217752%2F Conclusion: Postmenopausal women who are at high risk for cardiovascular diseases have a lower BMD than those who are not at high risk for cardiovascular diseases. Content Type Journal ArticleCategory Research ArticlePages 1-9DOI 10.2478/s11536-011-0101-6Authors Marina Rašić Popovic, Health Center Vranje, J. J. Lunge 1, 17500 Vranje, SerbiaIvan Tasić, Institute for Treatment & Rehabilitation, Niška Banja, SerbiaAleksandar Dimić, Institute for Treatment & Rehabilitation, Niška Banja, SerbiaSonja Stojanović, Institute for Treatment & Rehabilitation, Niška Banja, SerbiaBojana Stamenković, Institute for Treatment & Rehabilitation, Niška Banja, SerbiaSvetlana Kostić, Institute for Treatment & Rehabilitation, Niška Banja, SerbiaDejan Popović, Health Center Vranje, J. J. Lung... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5251807 Fri, 23 Sep 2011 15:51:28 +0100 5251807 http://www.medworm.com/index.php?rid=5227724&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg717756m8l31783n%2F Conclusion  there was a positive but non significant correlation between symptom score in patients with delayed GE compared to patients with normal GE, except correlation between early satiety and delayed GE. Content Type Journal ArticleCategory Research ArticlePages 1-5DOI 10.2478/s11536-011-0099-9Authors Simona Grad, 2nd Department of Internal Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj Napoca, 400431 Cluj Napoca, RomaniaLaura Poanta, 2nd Department of Internal Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj Napoca, 400431 Cluj Napoca, RomaniaDan Lucian Dumitrascu, 2nd Department of Internal Medicine, University of Medicine and Pharmacy “Iuliu Hatieganu” Cluj Napoca, 400431 Cluj Napoca, RomaniaMircea Dragotea... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227724 Thu, 15 Sep 2011 15:50:03 +0100 5227724 http://www.medworm.com/index.php?rid=5227725&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0514354n6h0p8681%2F Abstract  We are reporting the case of severe methemoglobinemia resulting from Almagel which was given for treatment of gastrointestinal ulcers after pancreatoduodenal resection. A 64 year old man was treated with Almagel A postoperatively. One day after treatment began, the patient reported what appeared to be cyanotic discolorations of his lips and fingers. (SpO2 80%, normal pO2). Two days later, the patient was diagnosed with methemoglobinemia via co-oximetry and treated with methylene blue. The causes of methemoglobinemia remained unclear, and Almagel A was reinitiated until the second episode of methemoglobinemia, was diagnosed and treated promptly. The dose of benzocaine in Almagel A (100 mg/5 ml) was sufficient enough to cause methemoglobinemia, confirmed using multiw... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227725 Thu, 15 Sep 2011 15:50:02 +0100 5227725 http://www.medworm.com/index.php?rid=5227726&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpk2u432v039u3ut7%2F We present a case of chronic Q-fever, complicated by myocarditis/pericarditis, where patient’s initial signs, symptoms and laboratory findings (i.e., protracted fever, oligoarthritis, erythema nodosum, positive antineutrophil cytoplasmic antibodies, monoclonal gammopathy) seemed to suggest an autoimmune disease. We also review the literature for autoimmune phenomena associated with Q-fever. Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.2478/s11536-011-0097-yAuthors Maria N. Gamaletsou, Department of Pathophysiology, Laikon General Hospital and Medical School, National and Kapodistrian University of Athens, Athens, 11527 GreeceAchilleas Gikas, Laboratory of Clinical Bacteriology, Parasitology, Zoonoses and Geographic Medicine, WHO Collaborating Center for Medit... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227726 Thu, 15 Sep 2011 15:49:53 +0100 5227726 http://www.medworm.com/index.php?rid=5227728&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn85314x6wl07337l%2F Conclusions: Reducing weight among overweight and maintaining stable weight among normal-weight men lower the risk of MetS. High LTPA level may additionally decrease the metabolic risk regardless of BMI. Content Type Journal ArticleCategory Research ArticlePages 1-7DOI 10.2478/s11536-011-0093-2Authors Magdalena Kwaśniewska, Department of Social and Preventive Medicine, Medical University of Lodz, Lodz, 90-647 PolandDorota Kaleta, Department of Social and Preventive Medicine, Medical University of Lodz, Lodz, 90-647 PolandAnna Jegier, Department of Sports Medicine, Medical University of Lodz, Lodz, 90-647 PolandTomasz Kostka, Department of Geriatrics, Medical University of Lodz, Lodz, 90-647 PolandElżbieta Dziankowska-Zaborszczyk, Department of Social and Preventive Medicine, Medi... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227728 Mon, 12 Sep 2011 15:51:31 +0100 5227728 http://www.medworm.com/index.php?rid=5227727&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx7134568843m1641%2F Conclusion  The authors wish to demonstrate the importance of multidisciplinary approach in the diagnostic process when symptoms of somatoform disorder are present. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.2478/s11536-011-0096-zAuthors Gabriella Inczedy-Farkas, Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083 Budapest, HungaryViktoria Remenyi, Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083 Budapest, HungaryAgnes Meszaros, Department of Clinical Psychology, Semmelweis University, 1083 Budapest, HungaryAniko Gal, Clinical and Research Center for Molecular Neurology, Department of Neurology, Semmelweis University, 1083 Budapest, Hun... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227727 Mon, 12 Sep 2011 15:51:31 +0100 5227727 http://www.medworm.com/index.php?rid=5227729&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6872181h61k8336n%2F Abstract  This documented case of mono-microbial Klebsiella pneumonia liver abscess with pulmonary metastasis in an adult in metropolitan Australian evokes important epidemiological, clinical and microbiological issues. These include the increasing incidence of this disease in western society, predisposing conditions, variability of presentation and the virulence of Klebsiella pneumonia. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.2478/s11536-011-0094-1Authors Dharmenaan Palamuthusingam, Princess Alexandra Hospital, Ipswich road, Woollongabba, Queensland 4102, AustraliaBrian Dwyer, Princess Alexandra Hospital, Ipswich road, Woollongabba, Queensland 4102, Australia Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227729 Mon, 12 Sep 2011 15:51:30 +0100 5227729 http://www.medworm.com/index.php?rid=5227730&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm168x55hq1486582%2F Conclusions  Improvement of NYHA functional class in patients with severe left ventricular dysfunction was statistically significant in patients submitted to CABG comparing to pharmacological treatment (p=0.00256). Improvement of QOL in particular groups was not statistically significant. Content Type Journal ArticleCategory Research ArticlePages 1-6DOI 10.2478/s11536-011-0095-0Authors Damian Kawecki, 2nd Department of Cardiology, Medical University of Silesia, 10, Marie Curie-Skłodowska Street, 41-800 Zabrze, PolandGrzegorz Kubiak, 2nd Department of Cardiology, Medical University of Silesia, 10, Marie Curie-Skłodowska Street, 41-800 Zabrze, PolandKatarzyna Orszulik, 2nd Department of Cardiology, Medical University of Silesia, 10, Marie Curie-Skłodowska Street, 41... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227730 Mon, 12 Sep 2011 15:51:28 +0100 5227730 http://www.medworm.com/index.php?rid=5227732&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl1651m13g773r326%2F We report a patient presenting in a coma with a metabolic acidosis on admission of pH 6.89, an increased anion gap of 29 mmol/L, and acute renal failure after the ingestion of an unknown quantity of EG. Intravenous bicarbonate and fluids and other supportive measures such as intubation, mechanical ventilation and vasopressors were started immediately. EG poisoning was confirmed by the finding of EG in the urine by gas chromatography. Intravenous ethanol and renal replacement therapy were started. The duration of ethanol infusion was guided by the serum pH and anion gap. After a long in-hospital stay, the patient survived with complete neurological recovery but mild renal dysfunction, confirming that, despite the late start of agressive intensive treatments, survival, and even nearly ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227732 Mon, 12 Sep 2011 15:51:26 +0100 5227732 http://www.medworm.com/index.php?rid=5227731&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvu515023588n4224%2F Abstract  A 62-year-old man presented to the Emergency Department with a 2-day history of right testicular pain. The initial diagnosis was orchiepididymitis (later found to be mistaken), and intravenous antibiotic treatment was started. Twenty-four hours later, the patient had mild pain in the right inguinal area and right infra-abdominal area. We performed an inguinal ultrasound that showed an incarcerated mass of mixed echogenicity in the right inguinal area. Surgery was performed because we thought the patient had an inguinal incarcerated hernia. Two days after the surgical procedure, the patient began to have fever and erythema and pain in the back. Abdominal computed tomography (CT) showed an acute pancreatitis with a peripancreatic collection from the pancreas to righ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227731 Mon, 12 Sep 2011 15:51:26 +0100 5227731 http://www.medworm.com/index.php?rid=5227733&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F317324658x23822t%2F Abstract  An episiotomy is a surgical incision through the perineum made to provide sufficient area for the delivery of the infant. About 10 to 95% of women who deliver will have episiotomy depending on which part of the world they are having delivery. Too early episiotomy causes extensive bleeding and too late episiotomy causes the excessive stretching of a pelvic floor and lacerations could not be prevented. According to widely accepted arguments, there are many benefits of episiotomy for the neonate: prevention of injuries, shoulder dystocia and mental retardation of the infant. Benefits for the mother are: reduction of severe lacerations, prevention of sexual dysfunction, prevention of urinary and fecal incontinence. But those things could also be complication... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5227733 Mon, 12 Sep 2011 15:51:25 +0100 5227733 http://www.medworm.com/index.php?rid=5210679&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa87m1r8307r05167%2F This study sought to explore the following issues 1) health-related quality of life (HRQoL) in Fabry patients relative to the general population 2) the quality of life (QoL) level in heterozygous females as compared to hemizygous males and the general population. A prospective, cross-sectional study was performed in patients diagnosed with Fabry disease in Poland (n=33). HRQoL was assessed with two generic questionnaires: the Medical Outcomes Study Short Form-36 (SF-36) and EuroQol questionnaire (EQ-5D), which includes the EQ-5D descriptive system and the EQ-visual analogue scale (EQ VAS), as well as a disease-specific author’s questionnaire. When measured with EQ-VAS, the subjective perception of health status was significantly lower in Fabry patients than that of the general popu... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5210679 Fri, 09 Sep 2011 06:05:16 +0100 5210679 http://www.medworm.com/index.php?rid=5210678&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2227l602207220m3%2F Abstract  Primary adrenal lymphoma (PAL) is an exceedingly rare disease. Because of its rareness, uncertain etiology, variable duration of survival, unremarkable clinical presentations and unsatisfied therapeutic strategies, its treatment has always been unsatisfactory. Here we report a 50-year-old male patient with primary bilateral adrenal diffuse large B-cell lymphoma. He was treated with surgery followed by combined chemotherapy using R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone). He achieved complete remission after 3 cycles of chemotherapy. At present, he is considered free of tumor at 3 years after chemotherapy. Our case report demonstrates that patients with primary bilateral adrenal diffuse large B-cell lymphoma may achieve a good ou... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5210678 Fri, 09 Sep 2011 06:05:16 +0100 5210678 http://www.medworm.com/index.php?rid=5210680&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh718753p2w5h2418%2F Abstract  Currarino syndrome was first described as a triad by Guido Currarino, an American radiologist in 1981. It is an autosomal dominant hereditary disease known by the triad of anorectal stenosis, anterior sacral defect, and a presacral mass that is most often an anterior sacral meningocele. We represent a 3 year boy with refractory constipation from birth, which had been wrongly diagnosed and treated as Hirschsprung’s disease since early childhood. The patient underwent urgent colostomy because of water intoxication due to bowel irrigation, and following investigations (CT, MRI) revealed anorectal anomaly and presacral mass compatible with Curarrino’s syndrome. Definitive operation was done with perineal approach, posterior sagittal anorectoplasty, with ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5210680 Fri, 09 Sep 2011 06:05:15 +0100 5210680 http://www.medworm.com/index.php?rid=5210682&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg46753055772mg56%2F Abstract  Fragile X syndrome is caused by dynamic mutation of FMR1 gene CpG island CGG repeats. The underlying mutational mechanism is not fully understood. Different microsatellite markers and SNP have previously been reported as markers associated with FMR1 CGG repeat instability. The aim of the present study was to identify specific haplotypes among Latvian FXS patients and the control group with respect to allelic stability. Eleven male FXS patients and 122 control male patients participated in the study. In total, 27 different DXS548-FRAXAC1-ATL1-FRAXAC2 haplotypes were found. The prevalent haplotype in the control group was 7-4-A-5+ (rel. frequency 0.327). The prevalent haplotype associated with the FXS group was 2-2-G-4 (rel. frequency 0.818; p < 0.0001). Grey zone... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5210682 Fri, 09 Sep 2011 06:05:13 +0100 5210682 http://www.medworm.com/index.php?rid=5210681&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1565482l49v50094%2F Abstract  The aim of this study was to determine the mean serum and follicular fluid LH and estradiol values in patients treated by IVF/ET (ICSI) after completed ovarian stimulation and to determine the range of values for these hormones with higher chances of conceiving pregnancies. All patients underwent stimulation in long agonistic protocol. Collected samples of body fluids (serum n = 31, follicular fluid n = 93) were centrifuged and supernatant was separated, aliquoted, frozen and stored at − 20°C. LH and E2 were measured in serum and follicular fluids. Cutoff value of E2 determined using follicular LH and follicular E2 correlation was 2100 nmol/L. If the E2 value was lower than 2100 nmol/L the ratio of results related to pregnancy was 29,4% (15/51). If the follicul... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5210681 Fri, 09 Sep 2011 06:05:13 +0100 5210681 http://www.medworm.com/index.php?rid=5192945&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmw2857236v1wk3g8%2F We report a case of orbital non-Hodgkin lymphoma initially diagnosed as Graves’ disease. A 65-year-old woman was admitted to the Department of Endocrinology with a diagnosis of a left eye tumor. On admission, apart from the tumor, exophthalmos and the upper eyelid proptosis were present. The lesion had been observed for two years before hospitalization. Due to the muscle infiltration, as detected on computed tomography scanning and magnetic resonance imaging, Graves’ disease was suggested. The thyroid function was normal. Further diagnosis performed during hospitalization revealed lymphoplasmacytic lymphoma. Lymphoma may manifest as a localized orbital tumor without extraorbital or constitutive symptoms. Rare orbital diseases, among others lymphoproliferations, should be taken in... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5192945 Thu, 01 Sep 2011 06:13:41 +0100 5192945 http://www.medworm.com/index.php?rid=5176346&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff2260p6n8325684g%2F Abstract  Although the significance of osteoporosis is well known worldwide, the number of patients undergoing therapy for this disease corresponds to a fraction only of the optimal proportion. In many countries, patients at a high risk of fracture — including those who have in fact sustained a typical fracture — do not receive therapy at all. Unawareness of the population, difficulties in accessing specialist care, as well as insufficient communications all contribute to the fact that a substantial percentage of patients discontinue drug therapy prematurely. Using information from a survey conducted in a club of osteoporotic patients, this paper discusses the achievements and substantiates the existence of patient associations, as well as emphasizes the need for establ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5176346 Sat, 27 Aug 2011 15:47:08 +0100 5176346 http://www.medworm.com/index.php?rid=5176345&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F85851734wwk6wm6v%2F Abstract  Ten years ago, a 73 year-old patient presented at our unit with a right nephritic colic and elevated serum creatinine (2.1 mg/dl). This was the first time that the patient had consulted for a urology workup. An abdominal X-ray was performed in which we observed a severe bilateral nephrocalcinosis with right ureteral lithiasis. One of the causes of nephrocalcinosis is distal renal tubular acidosis (dRTA), in that sense the patient presented metabolic acidosis (pH 7.25) together with normopotassaemia (4.4 meq/L) and normochlorine (105 mEq/L). A 24-hour urine test detected citrate (55 mg/dl), calcium (12 mg/dl) and pH of 6.5. A diuretic renogram showed the right relative renal function as 91.2% and left relative renal function as 8.8%. A test with bicarbonate and ace... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5176345 Sat, 27 Aug 2011 15:47:08 +0100 5176345 http://www.medworm.com/index.php?rid=5176349&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe20373v320582ug1%2F In conclusion, we found that a dietary pattern of high consumption of antioxidants (vitamin C, vitamin E, niacin), iron and potassium and low consumption of foods that are sources of sodium, decreased risk for gastric cancer. Our results require confirmation in future studies. Content Type Journal ArticleCategory Research ArticlePages 1-5DOI 10.2478/s11536-011-0079-0Authors Konstansa Lazarević, Public Health Institute Nis, Bulevar Dr Zorana Đinđića 50, 18000 Nis, SerbiaAleksandar Nagorni, Gastroenterology and Hepatology Clinic, Clinical Center Nis, Bulevar Dr Zorana Đinđića 48, 18000 Nis, SerbiaDragan Bogdanović, Public Health Institute Nis, Bulevar Dr Zorana Đinđića 50, 18000 Nis, SerbiaNataša Rančić, Public Health Institute Nis, Bulevar Dr Zorana Đinđića 50, 1... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5176349 Sat, 27 Aug 2011 15:47:07 +0100 5176349 http://www.medworm.com/index.php?rid=5176348&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fwu62471410428806%2F We present a 15,9-year old girl with pseudocyesis as a cause of abdomen enlargement, who comes from an ordinary family with a negative history of psychiatric illness. The organic etiology of her condition was excluded, and therefore she was treated with antidepressants which contributed to the resolution of her case. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.2478/s11536-011-0086-1Authors Veselin Škrabić, Department of Pediatrics, Split University Hospital Centre, 21000 Split, CroatiaŽeljka Vlastelica, Department of Pediatrics, Split University Hospital Centre, 21000 Split, CroatiaZoran Vučinović, Department of Endocrinology, Split University Hospital Centre, 21000 Split, Croatia Journal Central European Journal of MedicineOnline ISSN 1644-3640Pri... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5176348 Sat, 27 Aug 2011 15:47:07 +0100 5176348 http://www.medworm.com/index.php?rid=5176347&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F78044m6777826580%2F Conclusions  Attitude improvement towards modern contraception and promotion of knowledge of correct use of contraceptives among women with reproductive ages may lead to the prevention of recurrent abortion more effectively. EC: emergency contraceptive pill; NS: not significant Content Type Journal ArticleCategory Research ArticlePages 1-9DOI 10.2478/s11536-011-0080-7Authors Zoltan Kozinszky, Department of Obstetrics and Gynaecology, University Hospital of Northern Norway, Tromsø, Sykehusveien 10, N-9038 NorwayIván Devosa, Institute of Behaviour Science, Section of Behaviour Science, Faculty of General Medicine, University of Szeged, Szentháromság u. 5., H-6720 Szeged, HungaryJános Sikovanyecz, Department of Obstetrics and Gynaecology, Faculty of General Medicin... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5176347 Sat, 27 Aug 2011 15:47:07 +0100 5176347 http://www.medworm.com/index.php?rid=5176350&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm1233jv12gr7418m%2F Abstract  A rare case is presented concerning retroperitoneal hemorrhage in a 28-year-old patient after a cold knife conization and cervical suture reconstruction. Arteriovenous cervicoisthmic malformation is a risk factor that was identified in a hysterectomy sample. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.2478/s11536-011-0082-5Authors Dubravko Habek, University Department of Gynecology and Obstetrics University Hospital “Sveti Duh”, 10000 Zagreb, YugoslaviaTatjana Pavelić Turudić, University Department of Gynecology and Obstetrics University Hospital “Sveti Duh”, 10000 Zagreb, Yugoslavia Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5176350 Sat, 27 Aug 2011 15:47:06 +0100 5176350 http://www.medworm.com/index.php?rid=5171087&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6x4pq51667233773%2F Abstract  The present study was designed to delineate the effect of Giardia duodenalis in malnourished and renourished BALB/c mice. Control and renourished mice were fed with a standard pellet diet while malnourished mice were fed with a low protein (4.3 %) diet both before and after being challenged orally with actively growing G. duodenalis trophozoites. It was observed that malnourished mice had a greater severity and longer duration of Giardia infection compared with renourished mice. These malnourished mice also had less body mass but higher cyst and trophozoite counts. Malnourished mice infected with Giardia had significantly decreased level of total serum proteins, albumin, globulins, hemoglobin, leukocyte, and differential leukocyte counts compared with renourished mic... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5171087 Thu, 25 Aug 2011 05:44:52 +0100 5171087 http://www.medworm.com/index.php?rid=5171088&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F545163u40242l350%2F Conclusion  High school students in this region do not have enough knowledge on AIDS. They need education especially on ways of protection and spread of AIDS. Content Type Journal ArticleCategory Research ArticlePages 1-9DOI 10.2478/s11536-011-0077-2Authors Yusuf Onlen, Faculty of Medicine, Department of Infectious diseases and Clinical Microbiology, Mustafa Kemal University, 31000 Hatay, TurkeyNazan Savas, Faculty of Medicine, Department of Public Health, Mustafa Kemal University, 31000 Hatay, TurkeyCahit Ozer, Faculty of Medicine, Department of Family Medicine, Mustafa Kemal University, 31000 Hatay, TurkeyLütfü Savas, Faculty of Medicine, Department of Infectious diseases and Clinical Microbiology, Mustafa Kemal University, 31000 Hatay, TurkeyFaruk Incecik, Facult... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5171088 Thu, 25 Aug 2011 05:44:51 +0100 5171088 http://www.medworm.com/index.php?rid=5098966&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg818307n5mvk4745%2F Abstract  Increased aggregation of platelets during preeclampsia was shown in several studies, yet several others reported no change. The aim of our study was to investigate platelet aggregation in a group of patients suffering from preeclampsia. In a cross-sectional study blood samples were taken from 89 hospitalized patients in the third trimester of pregnancy: 38 were suffering from mild to moderate preeclampsia and 51 patients were without preeclampsia. From the blood samples platelet aggregation, secretion of adenine nucleotides from platelets, concentration of energy-rich adenine compounds and levels of cyclic adenosine-mono-phosphate and cyclic guanosine mono-phosphate in platelets were measured. In the patients with preeclampsia, the adenosine diphosphate threshold ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5098966 Wed, 03 Aug 2011 05:44:14 +0100 5098966 http://www.medworm.com/index.php?rid=5089439&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F85450400w6640251%2F Abstract  The skin of persons with atopic dermatitis (AD) is very susceptible to cutaneous infection, and some yeast species may also aggravate AD. The total yeast population of an AD patient’s skin and its relation with individual age and body part remains poorly characterized. The aim of this study was to clarify the differences in cutaneous yeast flora by age and body parts of AD patients. By swabbing affected body parts (hands, legs, face, neck or trunk), 241 samples were collected from patients with AD (132 children and 109 adults), and as controls, 40 samples were taken from healthy individuals (20 children, 20 adults). In all, 89 (36.9%) of samples were positive; the yeast isolated belonged to three genera: Candida (27.4%), Malassezia (6.6%), and Rhodotor... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5089439 Fri, 29 Jul 2011 16:06:21 +0100 5089439 http://www.medworm.com/index.php?rid=5081187&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff26313304n8821mn%2F Abstract  Paclitaxel is isolated from the Pacific yew. It can be obtained from the European yew, but only after chemical modification of the isolated compound by a semi-synthesis procedure. The procedure for total synthesis of paclitaxel is very complicated, involving multiple steps, and the yields of paclitaxel are meagre. This substance is also a metabolite of certain kinds of fungus. The microbiological pathway for producing paclitaxel compared with isolation from plant material involves shorter procuction times but a small yield. Cyclodextrins are usually used for improving the solubility of paclitaxel in aqueous media, with polymeric and other substances added. Paclitaxel has anticancer activity and use for preparing the formulations intravenously administrated to pati... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5081187 Tue, 26 Jul 2011 15:49:49 +0100 5081187 http://www.medworm.com/index.php?rid=5081188&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn2366q872r8h5155%2F Abstract  Due to the increasing number of infections related to injecting drug use, both the pattern of hepatitis C virus (HCV) transmission, and the circulating genotypes in Europe have changed. As there are little available data in this respect for Romania, the aim of our study was a preliminary analysis of the distribution of HCV genotypes circulating among injecting drug users (IDUs). Of the 45 IDUs evaluated (86.7% men, mean age − 27.6 ± 3.7 years, mean age at first drug use − 17.5 ± 3.9 years), 88.9% presented anti-HCV antibodies, with higher rates in those with an injecting history of more than 10 years; 57.8% of the subjects had detectable HCV viral load. Only 6.7% had markers of chronic hepatitis B infection, and none had anti-HIV antibodies. While HCV subtyp... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5081188 Tue, 26 Jul 2011 15:49:48 +0100 5081188 http://www.medworm.com/index.php?rid=5081189&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F66u61165k708w725%2F Abstract  We conducted a 10-cM genome-wide linkage scan in two extended pedigrees, ascertained from two diverse Dagestan genetic isolates with high aggregation of major depressive disorder (MDD) and suicides. Using genome wide multipoint parametric linkage analyses with short tandem repeat markers, we found two previously undetected genomic regions with significant linkage in isolate #6007 with LODs=3.1–3.4 at 2p13.2–p11.2 (and some signal in same region for #6008) and in 14q31.12–q32.13. We also obtained suggestive evidence for linkage with MDD at 9q33.3–q34.2 (#6008), 13q31.1–q31.2(#6007), 11p15(#6008), 17q25.3(#6007) and 19q13.31–q13.33 (#6008). Five regions (1p36.1–p35.2, 2p13.2–p11.2, 17q25.3, 18q22 and 22q12.3) demonstrated at least nominal linkage in b... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5081189 Tue, 26 Jul 2011 15:49:46 +0100 5081189 http://www.medworm.com/index.php?rid=5064678&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F303x54476t0572n5%2F Conclusions  According our study results, laparoscopic Heller myotomy was more effective than endoscopic pneumatic dilatation in achalasia treatment. Heartburn is a common complaint after these two procedures. Content Type Journal ArticlePages 1-5DOI 10.2478/s11536-011-0072-7Authors Mindaugas Kiudelis, Clinic of Surgery of Kaunas Medical University, Eiveniu 2, Kaunas, 50009 LithuaniaAntanas Mickevicius, Clinic of Surgery of Kaunas Medical University, Eiveniu 2, Kaunas, 50009 LithuaniaAlmantas Maleckas, Clinic of Surgery of Kaunas Medical University, Eiveniu 2, Kaunas, 50009 LithuaniaZilvinas Endzinas, Clinic of Surgery of Kaunas Medical University, Eiveniu 2, Kaunas, 50009 LithuaniaGediminas Kiudelis, Clinic of Gastroenterology of Kaunas Medical University, Eiveniu 2,... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5064678 Thu, 21 Jul 2011 18:15:34 +0100 5064678 http://www.medworm.com/index.php?rid=5041379&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft080h33308235t1k%2F Abstract  The aim of the study was to analyze changes of systolic and diastolic blood pressure values over five and ten years separately boys and girls and to estimate correlation between them. Three age groups from 8 centers in Serbia were evaluated: Group 1: 10 year old patients, Group 2: 15 year old and Group 3: 20 year old. Group with normal blood pressure values, prehypertensive and hypertensive group were analyzed. Regarding the period of follow-up we analyzed: 10/15 years period-children between 10 and 15 years, 15/20 years period-children between 15 and 20 years, and 10/20 years period-children between 10 and 20 years. Significant increase of diastolic blood pressure was noticed for both genders in 10/15 years period of prehypertensive population, while in hypertens... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5041379 Fri, 15 Jul 2011 05:53:50 +0100 5041379 http://www.medworm.com/index.php?rid=5031626&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyj80g8tq46657824%2F We report a 71-year-old male with microscopic polyangiitis (MPA) who developed sudden-onset, progressive, bilateral visual loss associated with a relapse of MPA symptoms. The patient was referred to our hospital, and treated with intravenous pulse steroid therapy and high-dose oral prednisolone. Although the right eye remained vision deficient, visual acuity in the left eye recovered. Ocular manifestations of MPA are quite uncommon. This case emphasizes the necessity of early detection and initiation of prompt therapy where ocular manifestations of MPA occur. Content Type Journal ArticlePages 1-3DOI 10.2478/s11536-011-0069-2Authors Yoshiro Horai, Department of Internal Medicine and Rheumatology, Clinical Research Center, National Hospital Organization, Kyushu Medical Center, 1-8... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5031626 Wed, 13 Jul 2011 06:14:43 +0100 5031626 http://www.medworm.com/index.php?rid=5022178&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftjh72r771690w817%2F Abstract  To evaluate the possibilities of physical activity in developing inmates’ healthy lifestyle and social skills. The research, which was conducted in 2009 in Pravieniskes First and Second Correction Houses, was local and cross-sectional using a written questionnaire. The questionnaire consisted of four groups of questions/statements: I — demographic questions; II — questions/statements about inmates’ physical (sports) activities (was created for this study) and III — assessment of inmates’ social skills. And IV — assessment of inmates’ self esteem. Sufficiently physically active inmates (n=185) comprised 57.8 percent of the total number of respondents. Inmates’ physical activity statistically significantly (p<0.05) correlates with their younger a... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022178 Sun, 10 Jul 2011 05:50:58 +0100 5022178 http://www.medworm.com/index.php?rid=5022180&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhk7762234n7006g1%2F Abstract  Organophosphate pesticides are known to induce oxidative stress and cause oxidative tissue damage, as has been reported in studies concerning acute and chronic intoxication with these compounds. Our objective was to investigate the activities of brain antioxidant enzymes and malonyldialdehyde, as well as the level of carbonyl groups, in rats sub-chronically intoxicated with chlorpyrifos at doses of 0.2, 2 and 5 mg per kg of body weight per day. It was found that chlorpyrifos induces change in brain antioxidant enzymes, such as superoxide dismutase, catalase and glutathione peroxidise, but to a different degree in comparison to proper control values; however, the elevated antioxidant enzymes activities failed to check lipid and protein peroxidation in the brain... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022180 Sat, 09 Jul 2011 05:59:28 +0100 5022180 http://www.medworm.com/index.php?rid=5022179&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frgx20518n321l884%2F Conclusions. MS patients diagnosed with depression significantly more often than non-depressed indicate that MS disturbs their family life; recommend to assign more attention to MS in general and to include more medications into reimbursement list. Content Type Journal ArticlePages 1-10DOI 10.2478/s11536-011-0059-4Authors Rytis Leonavičius, Department of Psychiatry of Medical Academy of Lithuanian University of Health Sciences, LT-50009 Kaunas, Republic of LithuaniaVirginija Adomaitienė, Department of Psychiatry of Medical Academy of Lithuanian University of Health Sciences, LT-50009 Kaunas, Republic of LithuaniaDarius Leskauskas, Department of Psychiatry of Medical Academy of Lithuanian University of Health Sciences, LT-50009 Kaunas, Republic of Lithuania Journal Central... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022179 Sat, 09 Jul 2011 05:59:28 +0100 5022179 http://www.medworm.com/index.php?rid=5022181&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F13m36950471n00r2%2F Abstract  Lung cancer is mainly a lifestyle-associated disease with poor prognosis and the lowest five year survival rate of all types of cancer. Lung cancers are divided into two main groups: small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC). Surgical treatment is generally indicated in cases of early stage NSCLC, and those patients treated with radical and aggressive surgery have a somewhat better survival rate. The main problems with lung cancer treatment are due to late diagnosis, rapidly developing drug resistance and side effects of the treatment that are experienced by almost all patients. The next step for distinguishing histologically complicated lung cancers and determining optimal treatment strategies is gene expression analysis. Supported by g... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022181 Sat, 09 Jul 2011 05:59:27 +0100 5022181 http://www.medworm.com/index.php?rid=5022182&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0624465h08178161%2F Abstract  A 76 year old patient underwent a laparoscopic rectal resection performed under thoracic epidural anaesthesia and general anaesthesia. He was inadvertently given 1 g of paracetamol epidural and reported a position-independent holocephalic headache one day later. A severe nausea and vomiting lead to a gastrointestinal bleeding. The last neurological examination after 3 months revealed no nausea, no headaches and no sensory disturbances. Content Type Journal ArticlePages 1-3DOI 10.2478/s11536-011-0066-5Authors Marius Gregor Dehne, Department for Anaesthesiology, Intensive Care Medicine, Emergency Medicine and Pain Therapy, Verbundkrankenhaus Bernkastel/Wittlich Koblenzer Str. 91, 54516 Wittlich, Germany Journal Central European Journal of MedicineOnline I... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022182 Sat, 09 Jul 2011 05:58:52 +0100 5022182 http://www.medworm.com/index.php?rid=5022183&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7728506v4386w357%2F We describe the case of a patient with a history of pulmonary sarcoidosis referred to our hospital for a screening mammography. Mammographic findings raised the suspicion for a breast mass. An additional breast ultrasound and fine -needle aspiration biopsy were performed. Finally, patient underwent a excisional biopsy of the left breast and the histopathological report revealed sarcoidosis. Content Type Journal ArticlePages 1-4DOI 10.2478/s11536-011-0068-3Authors Thomai Stavrogianni, Department of Radiology, Theagenion Anticancer Hospital of Thessaloniki, Thessaloniki, GreeceElisavet Psoma, Department of Radiology, Theagenion Anticancer Hospital of Thessaloniki, Thessaloniki, GreeceOlga Nikolaidou, Department of Radiology, Theagenion Anticancer Hospital of Thessaloniki, Thessalon... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022183 Sat, 09 Jul 2011 05:58:51 +0100 5022183 http://www.medworm.com/index.php?rid=5022184&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe48842044264435l%2F Conclusions  CSII provides significant improvement of blood glucose control with lower risk for hypoglycemia. Content Type Journal ArticlePages 1-7DOI 10.2478/s11536-011-0064-7Authors Saša P. Radenković, Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center Niš, Bulevar Dr Zorana Djindjica 48, 18000 Niš, SerbiaMilica M. Pešić, Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center Niš, Bulevar Dr Zorana Djindjica 48, 18000 Niš, SerbiaMilena D. Velojić Golubović, Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center Niš, Bulevar Dr Zorana Djindjica 48, 18000 Niš, SerbiaDragan N. Dimić, Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Clinical Center Niš, Bulevar Dr Zorana... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022184 Sat, 09 Jul 2011 05:58:46 +0100 5022184 http://www.medworm.com/index.php?rid=5022185&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw157957112126026%2F Conclusions  Abdominal Castleman’s disease lacks specific clinical manifestations. Definitive diagnosis requires histologic examination and excisional surgery is the method of choice for treatment. Content Type Journal ArticlePages 1-4DOI 10.2478/s11536-011-0067-4Authors Shu-Fang Si, Division of Ultrasound, Liaocheng People’s Hospital and Liaocheng Clinical School of Taishan Medical University, Liaocheng, Shandong, 252000 P. R. ChinaZong-Hui Wu, Shandong Provincial Medical Imaging Research Institute, Jinan, Shandong, 250012 P. R. ChinaLe-Xin Wang, School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, NSW 2678, Australia Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022185 Sat, 09 Jul 2011 05:58:44 +0100 5022185 http://www.medworm.com/index.php?rid=5022186&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd00388k32v45k297%2F Abstract  The aim of the prospective, multicenter project was to evaluate the effect of standardized information on the decision of woman when selecting application routes for combined hormonal contraceptives (CC). Selection the route of CC’s administration before and after consultation with the physician was evaluated on the group of 1326 women in 125 centres in the Czech Republic using a questionnaire. Analysis of the difference between the intended (4,1%) and selected (33,9%, CI 95% 31%–38%, 451 women) contraception shows that the vaginal ring preference increased by 29,8% (CI 97,5% 26,9%–32,8%, p < 0,0001). The difference for the weekly patch after (5,7%) and prior (4,2%) to the counseling of 1,4% was borderline statistically significant (CI 97,5%–0,002%–3,... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5022186 Sat, 09 Jul 2011 05:58:41 +0100 5022186 http://www.medworm.com/index.php?rid=5010913&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F00211j3x4g457j20%2F In conclusion almost half of the young healthy males participating in the study were detected to have vitamin D deficiency in winter. Low vitamin D concentrations are associated with a worse emotional state. Content Type Journal ArticlePages 1-9DOI 10.2478/s11536-011-0061-xAuthors Lina Lašaite, Institute of Endocrinology, Medical Academy of Lithuanian University of Health Sciences, Kaunas, LT-50009 LithuaniaIeva Gailyte, Institute of Endocrinology, Medical Academy of Lithuanian University of Health Sciences, Kaunas, LT-50009 LithuaniaPaulius Puzinas, Medical Academy of Lithuanian University of Health Sciences, LT-50009 Kaunas, LithuaniaRomualdas Tomas Preikša, Institute of Endocrinology, Medical Academy of Lithuanian University of Health Sciences, Kaunas, LT-50009 LithuaniaGint... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5010913 Wed, 06 Jul 2011 06:36:28 +0100 5010913 http://www.medworm.com/index.php?rid=5010914&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx485366513173hp1%2F Conclusions  Prostate cancer patients in Lithuania had greater survival rates than patients in Belarus. Observed differences in survival of prostate cancer patients needs to be explained in the future research. Content Type Journal ArticlePages 1-5DOI 10.2478/s11536-011-0058-5Authors Giedre Smailyte, Lithuanian Cancer Registry, Institute of Oncology, Vilnius University, LT-08660 Vilnius, LithuaniaYury Averkin, N.N. Alexandrov National Cancer Center of Belarus, 223040 Minsk, BelarusIlya Veyalkin, N.N. Alexandrov National Cancer Center of Belarus, 223040 Minsk, BelarusSergey Krasny, N.N. Alexandrov National Cancer Center of Belarus, 223040 Minsk, BelarusKarolis Ulinskas, Lithuanian Cancer Registry, Institute of Oncology, Vilnius University, LT-08660 Vilnius, Lithuania ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=5010914 Wed, 06 Jul 2011 06:36:27 +0100 5010914 http://www.medworm.com/index.php?rid=4994475&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5w3r544258702546%2F Abstract  The aim of the study is to investigate the most frequent cause of superficial mycoses in patients from the territory of city Niš Southeast Serbia in the period from 1998 to 2010. A total of 3223 samples from 2887 patients with suspected dermatomycoses were examined. Superficial mycoses were diagnosed using standard microbiology techniques (conventional microscopy and cultivation). Dermatophytes were determined on the basis of their macroscopic and microscopic morphological and morphometric characteristics. Morphometric characteristics were obtained by Laboratory Universal Computer Image Analysis system (Lucia M, 1996). Species of genus Candida were identified using the test of production of germ tube in sera, by growth on comertial chromatogen medium (Chromotogen... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4994475 Fri, 01 Jul 2011 17:43:01 +0100 4994475 http://www.medworm.com/index.php?rid=4994476&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F41hn237g5pp26070%2F Abstract  The melanocortin system plays a pivotal role in the regulation of appetite and energy balance. It was recognized to play an important role in the development of cancer-related cachexia, a debilitating condition characterized by progressive body wasting associated with anorexia, increased resting energy expediture and loss of fat as well as lean body mass that cannot be simply prevented or treated by adequate nutritional support. The recent advances in understanding of mechanisms underlying cancer-related cachexia led to consequent recognition of the melanocortin system as an important potential therapeutic target. Several molecules have been made available for animal experiments, including those with oral bioavailability, that act at various checkpoints of the... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4994476 Fri, 01 Jul 2011 17:42:59 +0100 4994476 http://www.medworm.com/index.php?rid=4994477&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkq31wjv7ul476225%2F We present the case of a 20-year-old man referred to the clinical geneticist because of mental retardation and dysmorphic features because of concerns about hereditability when his older, healthy brother was expecting a child. Deletion of proximal 3q arm was found with standard G-banding, and array comparative genomic hybridisation (array-CGH) was used to further locate the breakpoints. A unique interstitial deletion del 3q13.11q13.33 was confirmed. The first clinical symptoms in the 20-year-old were described at the age of 4 months when the pediatrician reported muscle hypertonia of the lower limbs, which later evolved into hypotonia. Later clinical observations revealed that the patient’s psychomotor development was delayed: he exhibited craniofacial abnormalities, cryptorchidism... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4994477 Thu, 30 Jun 2011 17:47:59 +0100 4994477 http://www.medworm.com/index.php?rid=4994478&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft422427m342k4h18%2F Abstract  Withdrawal-emergent adverse effects of antipsychotics are an infrequently identified condition which can appear during antipsychotic dose reduction and medication change. In this paper, we present the case of severe extrapyramidal symptoms after a dose reduction of risperidone is presented. A patient, 23 years of age, was admitted to a health care facility due to an unexpected change in his behavior, with paranoid delusions, incoherent thinking, and significant anxiety. An initial risperidone treatment was soon changed to zuclopenhixol. Subsequently, severe extrapyramidal symptoms appeared, after which the medication was switched back to resperidone. Following this treatment, the patient left the health care facility and stopped the medication of his own volition.... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4994478 Thu, 30 Jun 2011 17:47:58 +0100 4994478 http://www.medworm.com/index.php?rid=4994479&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj18n446ww4132655%2F Abstract  The aim of this study was to present the properties of insulin sensitivity indices formulas to justify selection of formulas to evaluate of insulin sensitivity for calculation from an oral glucose tolerance test (OGTT) data. Twelve of the most applicable formulae for ISI calculation were analyzed in the view of two sets of results: 1) point contrasts, calculated as the ratio of average ISI values in lean and obese groups of patients; and 2) interval contrasts, calculated as ratios of T from the two-sided t-test, evaluated as dimensionless, mutually comparable contrasts within a continuous scale. Statistical significance of individual ISIs in terms of their contrasts was evaluated by two-sided t-tests. P<0.001 was a considered statistically significance between ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4994479 Thu, 30 Jun 2011 17:47:57 +0100 4994479 http://www.medworm.com/index.php?rid=4994480&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr456705217206647%2F We examined the frequency of the alleles encoding methionine and valine at codon 129 in DNA isolated from 100 skeletal remains of individuals who lived between 10th and 13th century. Our results confirmed significant alteration in previously studied alleles frequency between the populations of medieval Polish Lands and contemporaries. The calculated frequency of the alleles in medieval Poland (51% as compared to contemporary 65% for 129Met, and appropriately 49% vs. 35% for 129Val) implies a selection process that shaped 129 Met-Val distribution profiles in the Middle Ages. We suggest that the study of the genetic relationship between past and present-day populations could be a useful tool to follow allelic composition of particular genes (here: of the PRNP) over a span of time which ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4994480 Thu, 30 Jun 2011 17:47:54 +0100 4994480 http://www.medworm.com/index.php?rid=4971451&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa3342532hjn03410%2F Conclusions  Intra-articular neostigmine provided similar pain control at motion as morphine during the trial, but it was better than placebo on the 2nd postoperative day. Similar pain control at rest, adjunct consumption and patient satisfaction recorded throughout the whole observation period in all groups. Content Type Journal ArticlePages 1-7DOI 10.2478/s11536-011-0049-6Authors Saule Svediene, Clinic of Anesthesiology and Intensive Care, Vilnius University, Vilnius, LithuaniaAudrius Andrijauskas, Clinic of Anesthesiology and Intensive Care, Vilnius University, Vilnius, LithuaniaJuozas Ivaskevicius, Clinic of Anesthesiology and Intensive Care, Vilnius University, Vilnius, Lithuania Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4971451 Thu, 23 Jun 2011 16:27:21 +0100 4971451 http://www.medworm.com/index.php?rid=4971452&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr78q5j3331844702%2F Abstract  Apparent hematological symptoms rarely dominate the clinical picture of an underlying non-hematological malignancy. Malignancy-associated eosinophilia can result from clonal or non-clonal proliferation of eosinophils. Here, we report the case of a 59-year-old man with metastatic adenocarcinoma of the lung with an unknown primary tumor site, which presented as hypereosinophilia, anemia, lymphadenopathy, weight loss, and malaise. Bone marrow biopsy disclosed metastatic adenocarcinoma positive in immunohistochemistry for cytokeratin 7. Further assessment of specimens obtained from the bronchoalveolar lavage and biopsy of the mediastinal lymph nodes confirmed the diagnosis of the metastatic lung cancer, although the primary tumor site remained undiscovered. This case ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4971452 Thu, 23 Jun 2011 16:27:19 +0100 4971452 http://www.medworm.com/index.php?rid=4896598&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3900r21820579622%2F In this study, we examined the relationship between the dimensions of the ductus arteriosus (diameter, length, capacity) and sex. We analyzed a total of 223 fetuses, 108 males and 115 females, ranging in age from four to eight months of intrauterinal life. All fetuses of normal karyotype were obtained from spontaneous abortions. None of the analyzed specimens demonstrated any visible malformations. The increase in the length and diameters of the ductus is linearly related to gestational age. The volumetric growth of this vessel was dependent on fetal age, according to the exponential function. The large number of analyzed specimens allows reliable determination of the ductus arteriosus dimensions in consecutive months of fetal life. The data obtained could be of prognostic value duri... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4896598 Wed, 25 May 2011 16:01:36 +0100 4896598 http://www.medworm.com/index.php?rid=4855263&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F78134w736523m031%2F Abstract  The aim of this study was to assess the associations of the body mass index (BMI), waist circumference (WC), and waist-to-height ratio (WHtR) with ischemic heart disease (IHD) and risk factors of IHD in the Lithuanian population aged 25 to 70 years. The cross-sectional health survey was carried out in Kaunas, which is the second largest city in Lithuania, and in five regions randomly selected from the northern, southern, eastern, western and central parts of Lithuania. Data from 2048 subjects (936 men and 1112 women) were analyzed. In both sexes, the odds ratios for reduced high density lipoprotein cholesterol, elevated triglycerides, high fasting blood glucose, and hypertension rose with an increasing quartile of BMI, WC, and WHtR. The likelihood of having IHD wa... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855263 Wed, 18 May 2011 18:21:04 +0100 4855263 http://www.medworm.com/index.php?rid=4855264&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmq5882768j841720%2F In conclusion, clinically diagnosed recurrent genital herpes during the third trimester of pregnancy associated with high risk for preterm birth. Content Type Journal ArticlePages 1-7DOI 10.2478/s11536-011-0044-yAuthors Ferenc Bánhidy, Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, Üllői út 78/A, H-1082 Budapest, HungaryIstván Dudás, Foundation for the Community Control of Hereditary Diseases, Bolgárkerék utca 3, H-1148 Budapest, HungaryAndrew E. Czeizel, Foundation for the Community Control of Hereditary Diseases, Bolgárkerék utca 3, H-1148 Budapest, Hungary Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855264 Wed, 18 May 2011 18:21:03 +0100 4855264 http://www.medworm.com/index.php?rid=4855265&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd651n52575451483%2F Abstract  Fourteen Sprague-Dawley male rats were randomly divided into 2 groups which were given CdCl2 at the doses of 0 and 1.5 mg /kg for 12 weeks. Before sacrifice, microCT scanning were performed on the proximal tibia and urine were collected for cadmium and N-acetyl-beta-D-glucosaminidase assay, then all of rats were sacrificed and blood was collected for biomarkers measurement; bone tissues were collected for bone mass, histology and biomechanical analysis. The cadmium in blood, urine, bone and kidney of rats treated with cadmium was significantly higher than those in the control group. The bone mineral density, and bone mineral ability of rats treated with cadmium were obviously decreased by 20%–50% compared to controls. Bone microstructure index and trabecular sep... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855265 Wed, 18 May 2011 18:21:02 +0100 4855265 http://www.medworm.com/index.php?rid=4855266&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq72u514714440273%2F We report a case of an apparently well-documented indapamide-induced hyponatremia. The initial diagnosis was made on the basis of dechallenge and rechallenge performed on two occasions. Further course of the disease, which proved inconsistent with our expectations, prompted us to look for another aetiology leading to the final diagnosis of the syndrome of inappropriate antidiuretic hormone secretion (SIADH) complicated by indapamide treatment. Content Type Journal ArticlePages 1-4DOI 10.2478/s11536-011-0027-zAuthors Jerzy Romaszko, NZOZ Pantamed Sp z o.o. w Olsztynie, ul. Pana Tadeusza 6, 10-461 Olsztyn, PolandRyszard Targonski, Medical Department, University of Warmia and Mazury in Olsztyn, ul. Żołnierska 14C, 10-900 Olsztyn, PolandLeszek Cichowski, Cardiology and Internal Dis... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855266 Wed, 18 May 2011 06:12:25 +0100 4855266 http://www.medworm.com/index.php?rid=4855267&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg3872630v6180377%2F This study was performed to identify the T-cell receptor Vβ repertoire and HLA-Cw genotype in twenty Mexicans of two different ethnicities with severe chronic plaque-type psoriasis. HLA-Cw typing was performed to detect the allele pattern by SSP-PCR. In parallel, RT-PCR and Western blot were used for the identification of the TCR Vβ expression in peripheral blood cells. We identified a variety of HLA-Cw alleles in this group of patients distinct from the widely known HLA-Cw 0602 Caucasian allele. Moreover, TCR Vβ-2 and Vβ-7 clone-type frequencies were different and statistically significant (P = 0.0280). We speculate that because of diverse genetic backgrounds, the susceptibility to disease and activation of T-cells for a proper immune response could be specific; therefore, the f... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855267 Wed, 18 May 2011 06:12:24 +0100 4855267 http://www.medworm.com/index.php?rid=4855269&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff441886j0p2u20x4%2F We report on two cases of spontaneous pneumomediastinum and pneumopericardium, in one case associated with pneumorrhachis, occurring in two children suffering from the novel influenza H1N1 virus infection. At the admission both children presented with fever, violent dry cough, dyspnea and tachypnea. Radiological studies showed sizeable pneumomediastinum and pneumopericardium in both patients. One of the patients also a pneumorrachis. Children were initially treated by intravenous broad-spectrum antibiotics, antipyretics and a cough sedative. Oral Oseltamivir (60 mg twice daily for 5 days) was administered after the diagnosis of influenza A (H1N1) virus infection. Patients’ clinical condition quickly improved and children were discharged with a partial resolution of their radiologic... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855269 Wed, 18 May 2011 06:12:23 +0100 4855269 http://www.medworm.com/index.php?rid=4855268&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyj6232163186l4n8%2F Abstract  Genetic variations of the antioxidant enzymes may influence the susceptibility to oxidative stress and consequently the development and progression of diabetic complications. The aim of the current study was to test the association between the −262C/T polymorphism in the catalase gene promoter and carotid atherosclerosis in Slovenian patients with type 2 diabetes. Two-hundred and eighty six diabetics and 150 healthy controls were enrolled in the study. Carotid atherosclerosis was quantified ultrasonographiocally by carotid intima-media thickness (CITM), plaque score and plaque type. Genotypes were determined using the real-time PCR. Fibrinogen concentration showed a borderline statistically significant difference due to catalase genotypes (p=0,05). No difference ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855268 Wed, 18 May 2011 06:12:23 +0100 4855268 http://www.medworm.com/index.php?rid=4855270&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F771131g5nqhn8508%2F Abstract  We aim to define the prevalence of nephrolithiasis, the impact of anatomic and metabolic factors to stone formation and prognosis of patients with autosomal dominant polycystic kidney disease in Albania. We included 200 patients with autosomal dominant polycystic kidney from 2002 to 2009. The patients underwent X-ray, renal ultrasonography. We performed the metabolic evaluation of blood and urine. Survival times were calculated as the time to dialysis, transplantation, or death. Kaplan-Meier product-limit survival curves were constructed. Log rank test was used to compare the survival curves. Nephrolithiasis was present in 116 of our patients with autosomal dominant polycystic kidney disease (58%), with a mean age 46.4±5.7 years. Sixty five patients with kidney s... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855270 Wed, 18 May 2011 06:12:22 +0100 4855270 http://www.medworm.com/index.php?rid=4855272&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6m2064878h855746%2F Abstract  The aim was to identify and quantify the association between the use of particular medications during the first trimester of pregnancy and selected congenital abnormalities (CAs) of newborns. Data were from the Czech National Registry of CAs. We used a case-control design, and collected total of 7285 cases and 9143 controls. Thiethylperazine and iron compounds had no effect on development of CAs. Lower odds ratio and potentially protective associations were found between CAs and bioflavonoids, folic acid, progesterone, levothyroxine, and iodine therapy. Since the protective effect of bioflavonoids was not described before, analysis of interaction with other drugs was performed. However, their protective effect was not confirmed and the strongest significant protec... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855272 Wed, 18 May 2011 06:12:21 +0100 4855272 http://www.medworm.com/index.php?rid=4855271&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe87532l3572r2288%2F We describe a case of nosocomial encephalitis and concurrent cerebellitis associated with Enterococcus faecium in a man, with extranodal natural killer/T-cell lymphoma, nasal type, who underwent high-dose chemotherapy and autologous peripheral blood stem cell transplantation. Brain magnetic resonance images showed lesions in the bihemispheral cerebellar cortex with swelling and several small lesions in both cerebral hemispheres. The blood and cerebrospinal fluid cultures were positive for vancomycin-resistant E. faecium. Vancomycin-resistant E. faecium can cause encephalitis and concurrent cerebellitis in an immunocompromised patient who underwent autologous peripheral blood stem cell transplantation. Content Type Journal ArticlePages 1-5DOI 10.2478/s11536-011-0041-1Authors Kyu... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855271 Wed, 18 May 2011 06:12:21 +0100 4855271 http://www.medworm.com/index.php?rid=4855273&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd0w02mm018732747%2F Abstract  Metastatic tumors of the pituitary are uncommon and usually asymptomatic. They are often incidental findings from imaging workups for other medical issues or from the assessment of primary tumors in other locations. Diabetes insipidus is the most common symptom resulting from pituitary tumors, including pituitary metastases. A 56-year-old woman with primary lung adenocarcinoma underwent video-assisted thoracic bilobectomy. Regular follow-up was unremarkable until 15 months after surgery, when she presented with polyuria and polydipsia suggestive of diabetes insipidus. A pituitary mass was found on brain magnetic resonance imaging; the diagnosis of lung adenocarcinoma metastasized to the pituitary was confirmed by trans-sphenoidal surgery and biopsy of the pituitar... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855273 Wed, 18 May 2011 06:12:19 +0100 4855273 http://www.medworm.com/index.php?rid=4855274&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv2284633k6r53047%2F Abstract  Subcutaneous sarcoidosis (SS) is an unusual and specific subtype of nodular sarcoidosis 1. The presence of SS with no elements of systemic manifestations is a rare condition: it is reported only in 1.4% to 6% of patients with systemic sarcoidosis, with the trunk being the most predilected area. Such cases with rare presentation are challenging for physicians because it can mimic several chronic infections, amyloidosis, hypothyroidism, lysosomal storage diseases and other conditions. Typical imaging (specially bilateral hilar adenopathies), histological exam and laboratory findings are the baseline to establish the diagnosis of sarcoidosis. In our case, the presence of subcutaneous manifestations avoided the performance of invasive procedures to get confirmation fr... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855274 Wed, 18 May 2011 06:12:18 +0100 4855274 http://www.medworm.com/index.php?rid=4855275&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk23x541524672078%2F Abstract  To determine the prevalence of high-risk HPV infection before first vaginal intercourse and after initiation of sexual activity in 14-22 years old girls, to find which HPV types occur most commonly. During the gynecologic exam cervical swabs were collected. Specimens were tested using Hybrid Capture 2 DNA test. In positive samples digene HPV genotyping test was performed. Subjects included 264 women, of whom 169 (64.0%) reported previous sexual activity and 95 (36.0%) had not yet had vaginal intercourse. There were 43 cases (16.3%) of high risk HPV, with 39 cases in those reporting sexual activity and 4 in virgins. Single strain HPV infection was detected in 62.8%, two strains in 23.2%, and three strains in 14.0% of subjects. HPV-16 was the most common type (20.9%... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4855275 Wed, 18 May 2011 06:12:17 +0100 4855275 http://www.medworm.com/index.php?rid=4833154&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fat3881q31w7k857g%2F Abstract  Some decades ago being a medical doctor was characterized unambiguously as a profession that offers help and serves the patients’ needs during medical treatment. In today’s society, this image of the medical profession has been substantially changed. The present paper aims to examine medical career choice motivations and preferences of choosing speciality, in the light of current social and economic changes in Hungary. The study was carried out by using a voluntary, self-administrated, questionnaire among first-year medical students and resident doctors in four medical faculties in Hungary. The career choice motivations of the first-year medical students and resident doctors are similar and match to the traditional health profession career choice motivations. ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4833154 Sat, 14 May 2011 15:51:28 +0100 4833154 http://www.medworm.com/index.php?rid=4807240&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn213k82683v61003%2F Abstract  The purpose was to determinate possible factors associated with psychosocial health through self-perceived health and psychological well-being among Serbian schoolchildren and adolescents. A cross-sectional study. The study is based on the 2006 National Health Survey of the population of Serbia. A total of 2,721 schoolchildren and adolescents were included. Face-to-face questionnaire and self-administered questionnaire were used for collection of data. For the assessment of psychosocial health we created two indicators (varibles): Self perceived health (using the categorical principal components), and Psychological well-being (using reliability analisys). Data were analyzed using descriptive statistics, Pearson’s correlation coeficient and categorical regression... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4807240 Wed, 04 May 2011 14:52:57 +0100 4807240 http://www.medworm.com/index.php?rid=4791061&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6473718k004131m6%2F Abstract  Gastrointestinal autonomic nerve tumors form an uncommon subcategory of stromal tumors of the intestinal tract although their histologic appearance is similar to other gastrointestinal stromal tumors. Our aim was to evaluate our experience in the diagnosis and therapy of these kinds of tumors. Two patients were admitted to the Pediatric Surgery Clinic in Niš with abdominal pain and a palpable mass in the abdomen. After excision, the tumor tissue was sampled, sent for histopathological diagnosis, and examined by light microscopy, immunohistochemistry, and electron microscopy. Postoperatively, both patients recovered without complications. The patient with the tumor bulk in the mesentery of the small bowel had no evidence of tumor progression 6 years after surgery.... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4791061 Wed, 04 May 2011 14:52:57 +0100 4791061 http://www.medworm.com/index.php?rid=4807241&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv8057353k4p51068%2F Abstract  Metabolic syndrome is a clinical term encompassing risk factors (obesity, insulin resistance, dyslipidemia and hypertension), which yield an increased risk for the development of diabetes mellitus type 2 and cardiovascular disorders in adolescence. Two sets of criteria for diagnosing metabolic syndrome were applied, the criteria for adults, specifically adapted for children, and the criteria defined by the International Diabetes Federation (IDF). A reliability analysis was conducted; sensitivity (SE), specificity (SP), positive predictive value (PPV) and negative predictive value (NPV) of applying certain criteria of both definitions of metabolic syndrome. Metabolic syndrome in adolescents was diagnosed much more frequently using the specific criteria (41%) in com... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4807241 Wed, 04 May 2011 14:52:56 +0100 4807241 http://www.medworm.com/index.php?rid=4783769&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn68m7wwr70lq6722%2F Abstract  Hip fracture in elderly people is associated with high morbidity and mortality. Therefore, it is important to identify risk factors that potentially influence outcomes after hip surgery. The main purpose of this study was to evaluate the relationship of anemia at admission and short-term outcomes after hip fracture. We studied 343 community-dwelling patients who underwent surgery for hip fracture from March 2009 to March 2010. Functional mobility at discharge, postoperative complications, hospital length of stay and in-hospital mortality were analyzed in respect to presence and severity of anemia at admission. Anemia (defined as hemoglobin levels < 13.0 g/dl for men and < 12.0g/dl for women) was present in 185 (53.9%) patients, of whom 54 (29.2%) were severe... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4783769 Mon, 02 May 2011 05:44:16 +0100 4783769 http://www.medworm.com/index.php?rid=4783770&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw6362j27w6628wpk%2F Abstract  Apelin (AP) and leptin (LEP) are adipokines with vasomotor actions. Taking into account the published data on the role of obesity in the development of pulmonary hypertension, we studied the implications of apelin on leptin relaxing effects on isolated rat pulmonary arteries. LEP had vasodilatatory effects on phenylephrine-precontracted rat pulmonary arteries from normal and ovalbumin-sensitized rats, but not on rats with monocrotaline-induced pulmonary hypertension. AP13 pretreatment increased LEP effects by one-half. Our studies revealed the existence of synergistic favorable effects of these adipokines on pulmonary vessels. Content Type Journal ArticlePages 1-7DOI 10.2478/s11536-011-0033-1Authors Irina L. Dumitriu, Department of Functional Sciences, Facul... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4783770 Mon, 02 May 2011 05:44:14 +0100 4783770 http://www.medworm.com/index.php?rid=4727178&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1842m6258v244273%2F Abstract  Ascariasis is a helminthic infection of global distribution, and intestinal obstruction is its most common gastrointestinal complication. This is a case of a 7-year-old boy admitted to Pediatric Surgery because of intestinal obstruction caused by ascariasis. On admission, the patient presented with colicky abdominal pain, bile-stained vomiting and meteorism. On physical examination, the patient was thin, pale, and dehydrated. An abdominal examination showed distention and diffuse tenderness. After admission, the patient had fecal vomiting and expulsion of worms through the mouth. Laboratory-test results showed leucocytosis, eosinophilia, hypoalbuminaemia, and hypochloremia. Abdominal radiographs and ultrasound studies were indicative of small-bowel obstruction due... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4727178 Thu, 14 Apr 2011 17:00:11 +0100 4727178 http://www.medworm.com/index.php?rid=4659894&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy86j6881r408x116%2F Abstract  The aim of this study was to investigate the prevalence and predictors of alcohol consumption among adolescents in one town in Central Serbia. A questionnaire was used to obtain data from 191 Serbian students aged 18 years regarding personal experience with alcohol consumption and cigarette smoking, along with sociodemographics data. Alcohol consumption was reported by 97.4% subjects, with 34.9% having the first experience with alcohol at the age of 14 years or less. Binge drinking (the intake of five or more drinks at one sitting) was reported by 37.8% subjects. Significantly higher consumption of beer (p<0.0001) and spirits (p=0.03) was observed in boys. The most common reason for both initiation and continuation of drinking, regardless of gender, were celebr... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4659894 Tue, 29 Mar 2011 17:30:12 +0100 4659894 http://www.medworm.com/index.php?rid=4632992&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2918754421302542%2F Conclusion  Large Morgagni hydatid is an extremely rare cause of tubal torsion that is usually detected at surgery. Surgical treatment should not be delayed, although a majority of adolescent females loose function of the twisted oviduct at the time of surgery. Content Type Journal ArticlePages 1-4DOI 10.2478/s11536-011-0023-3Authors Milan M. Terzic, School of Medicine, University of Belgrade, 11000 Belgrade, SerbiaNebojsa N. Arsenovic, Lincoln County Hospital, Cellular Pathology Department, PathLinks Pathology Services, Greetwell Road, Lincoln, LN2 5QY UKSanja B. Maricic, General Health Center “Savski Venac”, 11000 Belgrade, SerbiaIvana R. Babovic, Institute for Gynecology and Obstetrics, Clinical Center of Serbia, 11000 Belgrade, SerbiaIgor Z. Pilic, Institute f... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4632992 Tue, 22 Mar 2011 18:09:13 +0100 4632992 http://www.medworm.com/index.php?rid=4628204&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft8m26r2127177421%2F Abstract  Presented, is the case of a newborn with left-sided lung agenesis associated with total anomalous pulmonary venous return, atrial septal defect, polysplenia and hypospadias was described. Throughout the entire hospitalization period the newborn was in poor general condition, and dependent on mechanical ventilation with high oxygen concentrations. On day 20, the newborn died. According to the available literature, this case is unique in regard to the type and number of malformations. Content Type Journal ArticlePages 1-3DOI 10.2478/s11536-011-0024-2Authors Pavlović Vesna, Institute for Child and Youth Health Care of Vojvodina, Intensive Unit Care, Hajduk Veljkova 10, 21000 Novi Sad, SerbiaStojanović Vesna, Institute for Child and Youth Health Care of Vojvodin... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4628204 Mon, 21 Mar 2011 19:00:04 +0100 4628204 http://www.medworm.com/index.php?rid=4628205&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa681v5864w1u87u5%2F Conclusion  OP mostly manifested with mild-to-moderate respiratory symptoms and single or multiple lung infiltrates. OP varied in clinical and radiological forms. OP associated mostly with infection and/or neoplasm in our patients. Other reasons and cryptogenic origins of the disorder were rare. Content Type Journal ArticlePages 1-7DOI 10.2478/s11536-011-0025-1Authors Edvardas Danila, Clinic of Chest Diseases, Allergology and Radiology of Vilnius University, Santariškių g. 2, Vilnius LT, 08661 LithuaniaRolandas Zablockis, Clinic of Chest Diseases, Allergology and Radiology of Vilnius University, Santariškių g. 2, Vilnius LT, 08661 LithuaniaJolita Norkūnienė, Department of Mathematical Statistics of Vilnius Gediminas Technical University, Saulėtekio g. 11, Viln... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4628205 Mon, 21 Mar 2011 19:00:03 +0100 4628205 http://www.medworm.com/index.php?rid=4617605&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fevm47j861586w372%2F This study investigates the incidence of temporary and permanent recurrent laryngeal nerve palsy (RLNP) and possible risk factors for patients with different types of thyroid gland diseases. 1224 consecutive patients who underwent thyroidectomy for treatment of various thyroid diseases between the years 2001–2005. The rates of RLNP were evaluated. The surgeon and type of thyroid gland disorder were recognised as possible risk factors for RLNP. The incidence of temporary/permanent RLNP for the whole group was 4.5/0.8%. The rates of temporary RLNP for groups, classified as multinodular goitre, Graves’ disease, thyroid cancer or Hashimoto’s disease were 4.3%, 4.3%, 5.2% and 5.7%, respectively. The rates of permanent RLNP for the same groups were 0.4%, 0.9%, 1.6% and 1.9%, respecti... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617605 Sat, 19 Mar 2011 06:34:25 +0100 4617605 http://www.medworm.com/index.php?rid=4617606&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw21t302121767620%2F Abstract  Rapid prototyping (RP) is a technology used to produce physical models. The RP application is applied in the medical field to build anatomy models from high resolution multiplanar data such as Computed tomography (CT). CT of a female patient diagnosed with hip dysplasia was obtained prior to surgery. Specific software was used to prepare the physical model of the patient and was produced using fused deposition machine. Pre fused deposition models (FDM) were given to the orthopaedic surgeon to plan for the dysplastic hip dysplasia. The patient was scanned again using CT after surgery and a post model was produced. The outcome of the surgery was seen clearly by viewing the post model. Orthopaedic surgeon commented on his experience of using the models for the hip dy... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617606 Sat, 19 Mar 2011 06:34:24 +0100 4617606 http://www.medworm.com/index.php?rid=4617607&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd8k308p675664t22%2F Abstract  Mucoceles are common pathological lesions of the oral cavity, usually measuring up to 10 mm. The authors describe a case of deeply located buccal mucocele measuring 35 mm in diameter. The lesion was caused by facial injury in a 54-year old man. The lesion persisted for approximately 2.5 years and was difficult to diagnose because of its unusual size and atypical clinical symptoms. Preoperative ultrasonography excluded a tumor, and this was confirmed by histopathological examination. However, oncological alertness was considered necessary on account of ulcerated mucosa next to the lesion. The mucocele was removed through surgical excision, using a scalpel and tissue scissors. No recurrence was observed in 2.5 postoperative years. It is stressed that histopathologic... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617607 Sat, 19 Mar 2011 06:34:23 +0100 4617607 http://www.medworm.com/index.php?rid=4617608&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv34m71gk53257320%2F In conclusion, cerebral microbleeds may imply more advanced target organ damage than underlying LAD and ischemic subtypes of SAD. Content Type Journal ArticlePages 1-11DOI 10.2478/s11536-011-0019-zAuthors Kyusik Kang, Department of Neurology, Eulji General Hospital, 280-1 Hagye 1-dong, Nowon-gu, Seoul, 139-711 Republic of KoreaSeung-Hoon Lee, Department of Neurology, Seoul National University Hospital, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-744 Republic of KoreaBeom Joon Kim, Department of Neurology, Seoul National University Hospital, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-744 Republic of KoreaJae-Sung Lim, Department of Neurology, Seoul National University Hospital, 28 Yeongeon-dong, Jongno-gu, Seoul, 110-744 Republic of KoreaByung-Woo Yoon, Department of Neurology, Seoul Natio... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617608 Sat, 19 Mar 2011 06:34:22 +0100 4617608 http://www.medworm.com/index.php?rid=4617609&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu745086307138543%2F Abstract  The work of physicians in primary health care is essential in prevention and early detection of health risk factors. To determine the incidence of depression among patients in family medicine clinics, as well as the correlation between depression, risk factors and NCDs, and to determine correlation between depression (PHQ-9 score) and the level of physical activity. The pilot study was conducted from January to March 2010 on 100 patients using the Patient Health Questionnaire (PHQ-9) and the International Physical Activity Questionnaire (IPAQ). The family doctor randomly interviewed and measured patients’ weight, height, blood pressure, fasting blood glucose and cholesterol and noted the presence of earlier diagnosed non-communicable diseases. The data for 92 pa... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617609 Sat, 19 Mar 2011 06:34:21 +0100 4617609 http://www.medworm.com/index.php?rid=4617610&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk0nl741u173wxk23%2F We reported a case of bilateral lipoma arborescens in a male patient with associated marked patellofemoral osteoarthritis and described the MR imaging findings. Content Type Journal ArticlePages 1-3DOI 10.2478/s11536-011-0013-5Authors Evangelos Perdikakis, Department of Radiology, University of Crete, Stavrakia, 711 10 Heraklion, Crete, GreeceApostolos Karantanas, Department of Radiology, University of Crete, Stavrakia, 711 10 Heraklion, Crete, Greece Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617610 Sat, 19 Mar 2011 06:34:20 +0100 4617610 http://www.medworm.com/index.php?rid=4617612&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa68757234517t62x%2F Abstract  Generally, it is assumed that heart-rhythm disorders during hypoxia result from the interplay between the autonomic nervous system (ANS) and the direct effect of hypoxia on cardiorespiratory structures of the central nervous system and on the myocardium. Circadian variability in the ANS may substantially influence the electrical stability of the myocardium, and thus it is associated with the preconditioning protective mechanism. We designed our study using anaesthetized Wistar rats (ketamine/xylazine 100 mg/15 mg/kg, i.m., open chest experiments) to evaluate the effect of preconditioning (PC) induced by 1 to 3 cycles (1 PC–3 PC) of asphyxia (5 min. of artificial hypoventilation, VT = 0.5 ml/100 g of b.w., 20 breaths/min.) and reoxygenation (5 min. of artificial ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617612 Sat, 19 Mar 2011 06:34:19 +0100 4617612 http://www.medworm.com/index.php?rid=4617611&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft3j4807747x3331u%2F We report an association of LVHT with genetically confirmed hemochromatosis and polyneuropathy in a 54-year old Caucasian female. Content Type Journal ArticlePages 1-3DOI 10.2478/s11536-011-0015-3Authors Claudia Stöllberger, 2nd Medical Department, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030 Wien, ÖsterreichJosef Finsterer, Krankenanstalt Rudolfstiftung, Juchgasse 25, 1030 Wien, Österreich Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4617611 Sat, 19 Mar 2011 06:34:19 +0100 4617611 http://www.medworm.com/index.php?rid=4607294&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw2107hv01w45l766%2F We report the diagnostic evaluation, management, and intermediate-term outcomes of a rare variant of bladder cancer and concomitant Abdominal Aortic Aneurysm. A 62 year old male with gross haematuria and Abdominal Aortic Aneurysm was admitted to our hospital. Cystoscopy revealed a large bulky mass occupying the posterior bladder wall. The tumor was transurethrally resected and its histology showed a Sarcomatoid Carcinoma of the urinary bladder. Due to the aggressive behavior of the tumor and the risk of aneurysm rupture, concomitant endovascular exclusion of Aneurysm, total cystectomy with urinary diversion was performed. 12 months after radical surgery the patient was alive without any local recurrence, distant metastasis, and thrombosis of iliac axis. To our knowledge this study is... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4607294 Tue, 15 Mar 2011 17:20:49 +0100 4607294 http://www.medworm.com/index.php?rid=4607295&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F53h44073j4802532%2F Abstract  Epicardial adipose tissue (EAT) is metabolically active tissue that accumulates around the coronary arteries. Epicardial fat is a rich source of free fatty acids and may contribute to local inflammatory load by increased synthesis of inflammatory cytokines. Direct passage of bioactive molecules into the coronary arteries due to close contact with the vascular wall and the lack of fascia may contribute to the pathogenesis of coronary artery disease. Direct correlation between visceral fat and EAT defines the latter as an indirect marker of intra-abdominal visceral adiposity. EAT is related to anthropometric and clinical features of the metabolic syndrome (MS) and to hepatic transaminases as markers of steatohepatitis. An increase in EAT thickness is related to an i... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4607295 Tue, 15 Mar 2011 17:20:48 +0100 4607295 http://www.medworm.com/index.php?rid=4607296&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv3rx5422266h25x8%2F Abstract  In addition to its known classical roles, the renin angiotensin system (RAS) has more subtle functions which include the regulation of emotional responses. Previous studies regarding the anxiety related behavior of RAS have showed controversial results. There is also evidence that oxidative stress accompanies angiotensin II infusion, but the role of AT1/AT2 specific receptors is not clear. The aim of this study was to evaluate the effects of central angiotensin II receptor blockers on anxiety state and oxidative stress. Behavioral testing included elevated plus maze, while oxidative stress status was measured though the extent of a lipid peroxidation product (malondialdehyde-MDA) and the specific activity of some defense antioxidant enzymes (superoxide dismutase-S... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4607296 Tue, 15 Mar 2011 17:20:47 +0100 4607296 http://www.medworm.com/index.php?rid=4607297&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft8t68847276q65m1%2F In conclusion, ear CAs had a low diagnostic validity; thus it was necessary to reassess the data and to reclassify several cases. Content Type Journal ArticlePages 1-8DOI 10.2478/s11536-011-0014-4Authors László Paput, Department of Oto-Rhino-Laryngologic and Head/Neck Surgical Department, National Center for Healthcare Audit and Improvement, H-1062 Budapest, HungaryFerenc Bánhidy, Second Department of Obstetrics and Gynecology, Semmelweis University, School of Medicine, H-1082 Budapest, HungaryAndrew E. Czeizel, Foundation for the Community Control of Hereditary Diseases, H-1148 Budapest, Hungary Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4607297 Tue, 15 Mar 2011 17:20:31 +0100 4607297 http://www.medworm.com/index.php?rid=4607298&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj407752076166912%2F Abstract  To assess the impact of micrometastases in sentinel and non-sentinel lymph nodes on long-term survival rates of patients treated for colorectal cancer (CRC). Data of 57 patients diagnosed with CRC and treated in the Department of Surgical Oncology in Gdansk in the years 2002–2006 were retrospectively analyzed. Clinico-histopathological data were analyzed using chi-square tests. The effect on long-time survival rates was analyzed using Kaplan-Meier survival probability estimates. Identification of the SLN was performed using the blue dye staining method. All regional lymph nodes were subject to standard histopathological examination. Additionally in 32(56.14%) patients whose nodes were found negative for metastases on standard staining further immunohistochemical... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4607298 Tue, 15 Mar 2011 17:20:30 +0100 4607298 http://www.medworm.com/index.php?rid=4578762&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1q3n0105u193922h%2F We present a case of a woman who coughed up small amounts of fresh blood during 6 months and showed signs of cardiac failure. Several years previously, the patient underwent surgical removal of cystic lymphangiomas from the left ovary, both fallopian tubes and small intestine. A chest radiograph showed an 8-cm round shadow located in the middle lobe. A computerized tomography (CT) scan of the chest with contrast verified the existence of a cyst in the anterior mediastinum. The radiologist suggested that the cyst could have originated in the pericardium. One small cyst also appeared in the projection of the left cardiophrenic sinus. A CT scan with contrast of the patient’s abdomen showed multiple cystic formations in the liver, spleen, kidneys, and left parapelvic region. A fine-nee... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4578762 Thu, 10 Mar 2011 07:00:01 +0100 4578762 http://www.medworm.com/index.php?rid=4562427&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhk2233281572365u%2F Abstract  A 64-year-old man with a history of gallstones, common bile duct stones, chronic hepatitis B virus infection, and hepatic cirrhosis with a Child-Pugh score B was satisfactorily treated for hepatocellular carcinoma with radiofrequency ablation and transarterial chemoembolization. His course, however, was complicated by gallbladder actinomycosis 14 months after treatment, resulting in acute cholecystitis. Such a chain of events suggests that gallbladder actinomycosis may develop after radiofrequency ablation and transarterial chemoembolization in patients who are known to have gallstones and that asymptomatic gallstones should be treated before the application of nonsurgical, but invasive procedures for hepatocellular carcinoma. Content Type Journal ArticlePages... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4562427 Fri, 04 Mar 2011 10:53:53 +0100 4562427 http://www.medworm.com/index.php?rid=4485142&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnuu8j747m3262042%2F Abstract  The purpose of this study was to conduct a clinical and pathologic review of endometrial cancers diagnosed and surgically treated in our institution to evaluate results of treatment in relation to current international recommendations. We retrospectively evaluated the clinical history, treatment and follow-up of patients with histologically confirmed endometrial cancer treated in Faculty Hospital Nitra, Slovakia from 1990 to 2005. Data were abstracted regarding tumor histology, grade, age, parity, stage, diabetes, use of oral contraceptives, BMI, survival and treatment modalities including surgery, radiation therapy, chemotherapy, hormonal therapy, and combinations thereof. One hundred and thirty nine patients received surgical treatment for endometrial cancer: st... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4485142 Fri, 11 Feb 2011 11:53:24 +0100 4485142 http://www.medworm.com/index.php?rid=4485143&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw01p64612v341956%2F We describe a 52-year old lady who presented with progressive abdominal distension and computerized tomogram scan of the abdomen showing two pathologies; uterine and right renal tumour. It was initially thought to be two distinct tumours (double pathology). Radical nephrectomy and total abdominal hysterectomy with bilateral salpingo-oophorectomy was performed concurrently. Histopathological evaluation of the uterine and right renal tumour however surprised us with a rare form of metastasis from a renal tumour to the uterus. The method of differentiating primary renal cell carcinoma with uterine metastasis, from primary uterine carcinoma with renal metastasis, via immunohistochemistry, is described. Content Type Journal ArticlePages 1-3DOI 10.2478/s11536-011-0008-2Authors Christ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4485143 Fri, 11 Feb 2011 11:53:22 +0100 4485143 http://www.medworm.com/index.php?rid=4443066&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1h130n15514h6577%2F Abstract  Hyoscine and drotaverine effectiveness was compared for the purposes of achieving optimum distension following insufflation in CT colonography. The in vitro effects of hyoscine and drotaverine on tone and contractility of SM preparations isolated from different areas of human colon were studied by isometric registration of contractile activity. Both medications have a relaxing effect on SM preparations and inhibit their spontaneous contractions. The drotaverine-induced effects were reliably more marked than the hyoscine-induced ones. CT colonography was performed in 70 patients who were injected with equal doses of either hyoscine (n=32) or drotaverine (n=38). The degree of drug-induced distension in both groups was determined by measuring the lumen of the colon o... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4443066 Fri, 04 Feb 2011 09:25:02 +0100 4443066 http://www.medworm.com/index.php?rid=4443067&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn3787468310546n3%2F Abstract  Dyslipidemia, is a major risk factor for premature coronary artery disease. Our aim was to estimate the prevalence of dyslipidemia (blood lipid abnormalities) and other risk factors associated with coronary artery diseases among an adult population in northeastern China. Throughout the months of September and October of 2007, a population-based cross-sectional study was conducted and a total of 3,815 individuals were included. Total cholesterol (TC), high-density cholesterol (HDL-C), low-density cholesterol (LDL-C), and triglycerides (TG) were measured. A binary logistic regression analysis was conducted to determine risk factors associated with dyslipidemia. The prevalence of hypercholesterolemia, high LDL-C, low HDL-C, and hypertriglyceridemia were 17.3%, 27.8%,... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4443067 Thu, 03 Feb 2011 07:06:56 +0100 4443067 http://www.medworm.com/index.php?rid=4443068&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn68r5472066nj81q%2F Abstract  Cervical cancer morbidity and mortality in Lithuania is one of the biggest in the European Union. The main risk factor of cervical cancer is human papillomavirus (HPV). The deletion of the HPV E2 gene influences HPV DNA integration into the cell genome, as well as a rapid progression of cervical lesions. The purpose of this study is to determine HPV, its types, and HPV 16 integration in different grades of cervical intraepithelial neoplasias (CIN). 253 women with cytological lesions were involved in the study. After a histology, 31 women were diagnosed with CIN I, 35 with CIN II, and 51 with CIN III. The biggest prevalence of HPV infection was detected in women younger than 25 years old (69.7%) and in women with CIN II (90.9%). HPV 16 was detected in 67.8% of all ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4443068 Thu, 03 Feb 2011 07:06:55 +0100 4443068 http://www.medworm.com/index.php?rid=4412639&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr689pu67640vj306%2F Abstract  RNA interference is a technique that has become popular in the past few years. This is a biological method to detect the activity of a specific gene within a cell. RNAi is the introduction of homologous double stranded RNA to specifically target a gene’s product resulting in null or hypomorphic phenotypes. This technique involves the degradation of specific mRNA by using small interfering RNA. Both microRNA (miRNA) and small interfering RNA (siRNA) are directly related to RNA interference. RNAi mechanism is being explored as a new technique for suppressing gene expression. It is an important issue in the treatment of various diseases. This review considers different aspects of RNAi technique including its history of discovery, molecular mechanism, gene expressio... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4412639 Tue, 25 Jan 2011 23:35:39 +0100 4412639 http://www.medworm.com/index.php?rid=4412642&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg273521442j17237%2F Abstract  In search of biological marker in multiple sclerosis (MS), total-tau and phospho-tau (Thr181) concentrations were established in CSF and serum of 78 patients with MS, using commercially available kits. Serum and CSF concentrations of IgG, IgM, and albumin were assayed simultaneously to calculate quotients and indices of intrathecal synthesis. Serum t-tau detection was strikingly low (23.1%); therefore, this factor was excluded from further analysis. Serum p-tau levels did not correlate with any of indices or quotients. Unexpectedly, CSF t-tau and p-tau showed an inverse relation with MSSS and EDSS, which has not been published elsewhere. Our results do not support utility of serum t-tau and p-tau as surrogate markers for MS. Content Type Journal ArticlePages 1... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4412642 Tue, 25 Jan 2011 23:35:38 +0100 4412642 http://www.medworm.com/index.php?rid=4412641&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq47872jl852t2543%2F Abstract  Early diagnosis of osteoporosis and estimation of subjects that are at high risk for fracture, is neccesary for osteoporosis treatment. Dual-energy X-ray absorptometry (DXA) is a modern method for bone mineral density (BMD) evaluation. However, along BMD, clinical risk factors may significantly influence fracture development. Therefore, FRAX algorithm was designed for the assessment of a ten-year risk for serious osteoporotic fractures (SOF), as well as hip fractures. In the current study, we tried to evaluate the possible lumbal spine and hip BMD influence on ten year risk for SOF and hip fractures and potential role of FRAX in predicting the therapy in postmenopausal women with osteopenia. We performed the study on 385 postmenopausal women. According to the DXA ... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4412641 Tue, 25 Jan 2011 23:35:38 +0100 4412641 http://www.medworm.com/index.php?rid=4412640&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F17012k2867u51723%2F Abstract  Posterior ankle impingement syndrome represents an important cause of chronic ankle pain and has been extensively described in the orthopaedic and radiology literature. A rare case of this painful hindfoot disorder that resulted from two concurrent developmental anomalies is presented herein. Content Type Journal ArticlePages 1-3DOI 10.2478/s11536-011-0001-9Authors Evangelos Perdikakis, Department of Radiology, University of Crete, Stavrakia, 711 10 Heraklion, Crete, GreeceApostolos Karantanas, Department of Radiology, University of Crete, Stavrakia, 711 10 Heraklion, Crete, Greece Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4412640 Tue, 25 Jan 2011 23:35:38 +0100 4412640 http://www.medworm.com/index.php?rid=4374043&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F672437w2420771g8%2F Content Type Journal Article Journal Central European Journal of MedicineOnline ISSN 1644-3640Print ISSN 1895-1058 (Source: Central European Journal of Medicine) Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4374043 Thu, 20 Jan 2011 16:59:09 +0100 4374043 http://www.medworm.com/index.php?rid=4364331&cid=s_33446_22_f&fid=33446&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F556w74xlh0x87140%2F We present a case of molar tissue within a uterine myoma, the first such entity reported in the literature. In May 2006, a thirty-eight year old infertility patient was admitted for myomectomy. She had anamnesis for chronic pelvic inflammatory disease and surgeries performed for tubal pregnancies. After the sixth intracytoplasmal spermatozoa injection procedure performed in January 2006, she conceived, but curettage was performed in March 2006 for a missed abortion. Following the routine preoperative evaluation in May 2006, four months after the last artificial reproductive technology procedure, myomectomy was performed as uneventful operation, but the histological report appeared unusual, showing degenerated chorionic villi within the uterine myoma. Molar tissue within uterine myoma... Central European Journal of Medicine journals http://www.medworm.com/rss/comments.php?id=4364331 Sat, 15 Jan 2011 01:06:26 +0100 4364331