MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Chronobiology International' source. Thu, 09 Feb 2012 14:32:02 +0100 http://www.medworm.com/index.php?rid=5576892&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217095%26dopt%3DAbstract Authors: Randler C, Vollmer C PMID: 22217095 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576892 Tue, 10 Jan 2012 07:02:02 +0100 5576892 http://www.medworm.com/index.php?rid=5576891&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217096%26dopt%3DAbstract Authors: Rakshit K, Krishnan N, Guzik EM, Pyza E, Giebultowicz JM Abstract Circadian clocks maintain temporal homeostasis by generating daily output rhythms in molecular, cellular, and physiological functions. Output rhythms, such as sleep/wake cycles and hormonal fluctuations, tend to deteriorate during aging in humans, rodents, and fruit flies. However, it is not clear whether this decay is caused by defects in the core transcriptional clock, or weakening of the clock-output pathways, or both. The authors monitored age-related changes in behavioral and molecular rhythms in Drosophila melanogaster. Aging was associated with disrupted rest/activity patterns and lengthening of the free-running period of the circadian locomotor activity rhythm. The expression of core clock genes was ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576891 Tue, 10 Jan 2012 07:01:53 +0100 5576891 http://www.medworm.com/index.php?rid=5576890&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217097%26dopt%3DAbstract This study investigated the functional linkage between food availability and activity behavior in the Palaearctic Indian night migratory blackheaded bunting (Emberiza melanocephala) subjected to artificial light-dark (LD) cycles. Two experiments were performed on photosensitive birds. In the first one, birds were exposed to short days (LD 10/14; Experiment 1A), long days (LD 13/11; Experiment 1B), or increasing daylengths (8 to 13 h light/d; Experiment 1C) and presented with food either for the whole or a restricted duration of the light period. In Experiments 1A and 1B, illumination of the light and dark periods or of the dark period, alone, was changed to assess the influence of the light environment on direct and circadian responses to food cycles. In the second experiment, birds were... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576890 Tue, 10 Jan 2012 07:01:43 +0100 5576890 http://www.medworm.com/index.php?rid=5576889&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217098%26dopt%3DAbstract Authors: Fonken LK, Haim A, Nelson RJ Abstract With the widespread adoption of electrical lighting during the 20th century, human and nonhuman animals became exposed to high levels of light at night for the first time in evolutionary history. This divergence from the natural environment may have significant implications for certain ecological niches because of the important influence light exerts on the circadian system. For example, circadian disruption and nighttime light exposure are linked to changes in immune function. The majority of studies investigating the effects of light exposure and circadian disruption on the immune system use nocturnal rodents. In diurnal species, many hormones and immune parameters vary with secretion patterns 180° out of phase to those of nocturnal... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576889 Tue, 10 Jan 2012 07:01:34 +0100 5576889 http://www.medworm.com/index.php?rid=5576888&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217099%26dopt%3DAbstract Authors: Conroy DA, Hairston IS, Arnedt JT, Hoffmann RF, Armitage R, Brower KJ Abstract Sleep disturbances in alcohol-dependent (AD) individuals may persist despite abstinence from alcohol and can influence the course of the disorder. Although the mechanisms of sleep disturbances of AD are not well understood and some evidence suggests dysregulation of circadian rhythms, dim light melatonin onset (DLMO) has not previously been assessed in AD versus healthy control (HC) individuals in a sample that varied by sex and race. The authors assessed 52 AD participants (mean ± SD age: 36.0 ± 11.0 yrs of age, 10 women) who were 3-12 wks since their last drink (abstinence: 57.9 ± 19.3 d) and 19 age- and sex-matched HCs (34.4 ± 10.6 yrs, 5 women). Following a 23:00-06:00 ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576888 Tue, 10 Jan 2012 07:01:25 +0100 5576888 http://www.medworm.com/index.php?rid=5576887&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217100%26dopt%3DAbstract Authors: Killgore WD, Grugle NL, Balkin TJ Abstract Recent evidence suggests that sleep deprivation leads to suboptimal decision-making on the Iowa Gambling Task (IGT), a pattern that appears to be unaffected by moderate doses of caffeine. It is not known whether impaired decision-making could be reversed by higher doses of caffeine or by other stimulant countermeasures, such as dextroamphetamine or modafinil. Fifty-four diurnally active healthy subjects completed alternate versions of the IGT at rested baseline, at 23 and 46 h awake, and following a night of recovery sleep. After 44 h awake, participants received a double-blind dose of caffeine (600 mg), dextroamphetamine (20 mg), modafinil (400 mg), or placebo. At baseline, participants showed a normal pattern of advant... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576887 Tue, 10 Jan 2012 07:01:16 +0100 5576887 http://www.medworm.com/index.php?rid=5576886&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217101%26dopt%3DAbstract This study assessed the influence of sleep loss and circadian rhythm on executive inhibitory control (i.e., the ability to inhibit conflicting response tendencies due to irrelevant information). Twelve ordinarily diurnally active, healthy young male participants performed the Stroop and the Simon task every 3 h in a 40-h constant routine protocol that comprised constant wakefulness under controlled behavioral and environmental conditions. In both tasks, overall performance showed clear circadian rhythm and sleep-loss effects. However, both Stroop and Simon interference remained unchanged across the 40 h of wakefulness, suggesting that neither cumulative sleep loss nor the circadian clock affects executive inhibitory control. The present findings challenge the widely held view that exec... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576886 Tue, 10 Jan 2012 07:01:07 +0100 5576886 http://www.medworm.com/index.php?rid=5576885&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217102%26dopt%3DAbstract Authors: Sasaki M, Ando H, Fujimura A Abstract To prevent recurrence of cerebrovascular disease (CVD), adequate control of blood pressure (BP) is extremely important for the treatment of hypertensive CVD patients. As absence of the nocturnal fall of BP by the expected 10-20% from daytime levels is reported to exaggerate target organ injury, 24-h ambulatory blood pressure monitoring (ABPM) was conducted, especially to obtain data during nighttime sleep. Forty-eight elderly bedridden chronic phase CVD hypertensive patients (assessed 1-3 mo after CVD accident) participated. As a group, nocturnal BP was higher than diurnal BP, whereas nocturnal pulse rate was lower than diurnal pulse rate. The nocturnal BP fall was blunted in most (∼90%) of the patients. These results suggest that to... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576885 Tue, 10 Jan 2012 07:00:58 +0100 5576885 http://www.medworm.com/index.php?rid=5576884&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217103%26dopt%3DAbstract Authors: Komoto S, Kondo H, Fukuta O, Togari A Abstract Most living organisms exhibit circadian rhythms that are generated by endogenous circadian clocks, the master one being present in the suprachiasmatic nuclei (SCN). Output signals from the SCN are believed to transmit standard circadian time to peripheral tissue through sympathetic nervous system and humoral routes. Therefore, the authors examined the expression of clock genes following treatment with the β-adrenergic receptor agonist, isoprenaline, or the synthetic glucocorticoid, dexamethasone, in cultured human osteoblast SaM-1 cells. Cells were treated with 10(-6) M isoprenaline or 10(-7) M dexamethasone for 2 h and gene expressions were determined using real-time polymerase chain reaction (PCR) analysis. Treatment with... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576884 Tue, 10 Jan 2012 07:00:48 +0100 5576884 http://www.medworm.com/index.php?rid=5576883&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217104%26dopt%3DAbstract This study investigates developmental and behavioral correlates between larval ethanol exposure and the adult circadian clock in Drosophila melanogaster, a well-established model for studying circadian rhythms and effects of ethanol exposure. We reared Drosophila larvae on 0%, 10%, or 20% ethanol-supplemented food and assessed effects upon eclosion and the free-running period of the circadian rhythm of locomotor activity. We observed a dose-dependent effect of ethanol on period, with higher doses resulting in shorter periods. We also identified the third larval instar stage as a critical time for the developmental effects of 10% ethanol on circadian period. These results demonstrate that developmental ethanol exposure causes sustainable shortening of the adult free-running period in Drosop... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576883 Tue, 10 Jan 2012 07:00:39 +0100 5576883 http://www.medworm.com/index.php?rid=5576882&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217105%26dopt%3DAbstract Authors: Bastianini S, Silvani A, Berteotti C, Martire VL, Zoccoli G Abstract A daily rhythm of blood pressure (BP), with maximum values in the activity period, carries important prognostic information. The extent to which this rhythm depends on behavioral factors remains debated. Mice are the species of choice for functional genomics. In mice, episodes of wakefulness and sleep are not restricted to particular daily periods, allowing BP in each wake-sleep state to be measured at each time of day. The aim of this study was to investigate whether a circadian rhythm of BP is manifest in each wake-sleep state in mice. Mice with B6 genetic background (n = 26) were implanted with a telemetric BP transducer and electrodes to discriminate wake-sleep states and recorded while housed und... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576882 Tue, 10 Jan 2012 07:00:29 +0100 5576882 http://www.medworm.com/index.php?rid=5576881&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217106%26dopt%3DAbstract Authors: Kyba CC, Hölker F PMID: 22217106 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576881 Tue, 10 Jan 2012 07:00:20 +0100 5576881 http://www.medworm.com/index.php?rid=5576880&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22217107%26dopt%3DAbstract Authors: Rea MS, Brons JA, Figueiro MG PMID: 22217107 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576880 Tue, 10 Jan 2012 07:00:11 +0100 5576880 http://www.medworm.com/index.php?rid=5576893&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22214237%26dopt%3DAbstract Authors: Vollmer C, Michel U, Randler C Abstract External zeitgebers synchronize the human circadian rhythm of sleep and wakefulness. Humans adapt their chronotype to the day-night cycle, the strongest external zeitgeber. The human circadian rhythm shifts to evening-type orientation when daylight is prolonged into the evening and night hours by artificial light sources. Data from a survey of 1507 German adolescents covering questions about chronotype and electronic screen media use combined with nocturnal satellite image data suggest a relationship between chronotype and artificial nocturnal light. Adolescents living in brightly illuminated urban districts had a stronger evening-type orientation than adolescents living in darker and more rural municipalities. This result persisted ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5576893 Tue, 03 Jan 2012 05:00:00 +0100 5576893 http://www.medworm.com/index.php?rid=5415193&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080729%26dopt%3DAbstract In conclusion, abnormal expression levels of core clock genes in CRC tissue may be related to the process of tumorigenesis and exert an influence on host/tumor interactions. (Author correspondence: g.mazzoccoli@tin.it ). PMID: 22080729 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415193 Thu, 17 Nov 2011 16:21:00 +0100 5415193 http://www.medworm.com/index.php?rid=5415192&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080730%26dopt%3DAbstract Authors: Zhu Y, Stevens RG, Hoffman AE, Tjonneland A, Vogel UB, Zheng T, Hansen J Abstract Epigenetic association studies have demonstrated differential promoter methylation in the core circadian genes in breast cancer cases relative to cancer-free controls. The current pilot study aims to investigate whether epigenetic changes affecting breast cancer risk could be caused by circadian disruption through exposure to light at night. Archived DNA samples extracted from whole blood of 117 female subjects from a prospective cohort conducted in Denmark were included in this study. A polymerase chain reaction (PCR)-based method was used for detection of gene-promoter methylation, whereas genome-wide methylation analysis was performed using the Illumina Infinium Methylation Chip. Long-term... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415192 Thu, 17 Nov 2011 16:20:52 +0100 5415192 http://www.medworm.com/index.php?rid=5415191&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080731%26dopt%3DAbstract Authors: Lone SR, Sharma VK Abstract In ant colonies a large proportion of individuals remain inside nests for most of their lives and come out only when necessary. It is not clear how, in a nest of several thousand individuals, information about local time is communicated among members of the colony. Central to this seem to be circadian clocks, which have an intrinsic ability to keep track of local time by entraining to environmental light-dark, temperature, and social cycles. Here, the authors report the results of their study aimed at understanding the role of cyclic social interactions in circadian timekeeping of a day-active species of carpenter ant Camponotus paria. The authors found that daily social interactions with visitors (worker ants) was able to synchronize the circad... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415191 Thu, 17 Nov 2011 16:20:43 +0100 5415191 http://www.medworm.com/index.php?rid=5415190&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080732%26dopt%3DAbstract Authors: Sch Ttner K, Simonneaux VR, Vuillez P, Steinlechner S, P Vet P, Weinert D Abstract Djungarian hamsters (Phodopus sungorus) bred at the Institute of Halle reveal three different circadian phenotypes. The wild type (WT) shows normal locomotor activity patterns, whereas in hamsters of the DAO (delayed activity onset) type, the activity onset is continuously delayed. Since the activity offset in those hamsters remains coupled to ?light-on,? the activity time becomes compressed. Hamsters of the AR (arrhythmic) type are episodically active throughout the 24?h. Previous studies showed that a disturbed interaction of the circadian system with the light-dark (LD) cycle contributes to the phenomenon observed in DAO hamsters. To gain better insight into the underlying mechanisms, the... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415190 Thu, 17 Nov 2011 16:20:34 +0100 5415190 http://www.medworm.com/index.php?rid=5415189&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080733%26dopt%3DAbstract Authors: Peres I, Vetter CL, Blautzik J, Reiser M, P Ppel E, Meindl T, Roenneberg T, Gutyrchik E Abstract Neuroimaging is increasingly used to study the motor system in vivo. Despite many reports of time-of-day influences on motor function at the behavioral level, little is known about these influences on neural motor networks and their activations recorded in neuroimaging. Using functional magnetic resonance imaging (fMRI), the authors studied 15 healthy subjects (9 females; mean???SD age: 23???3 yrs) performing a self-paced finger-tapping task at different times of day (morning, midday, afternoon, and evening). Blood-oxygenation-level-dependent signal showed systematic differences across the day in task-related motor areas of the brain, specifically in the supplementary motor are... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415189 Thu, 17 Nov 2011 16:20:26 +0100 5415189 http://www.medworm.com/index.php?rid=5415188&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080734%26dopt%3DAbstract Authors: Wu T, Sun L, Zhuge F, Guo X, Zhao Z, Tang R, Chen Q, Chen L, Kato H, Fu Z Abstract The timing of meals has been suggested to play an important role in circadian regulation and metabolic health. Three meals a day is a well-established human feeding habit, which in today's lifestyle may or may not be followed. The aim of this study was to test whether the absence of breakfast or supper significantly affects the circadian system and physiological function. The authors developed a rat model for their daily three meals study, whereby animals were divided into three groups (three meals, TM; no first meal, NF; no last meal, NL) all fed with the same amount of food every day. Rats in the NF group displayed significantly decreased levels of plasma triglyceride (TG), total cholester... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415188 Thu, 17 Nov 2011 16:20:17 +0100 5415188 http://www.medworm.com/index.php?rid=5415187&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080735%26dopt%3DAbstract Authors: Zimmermann LK Abstract Social synchronizers of morningness-eveningness, or chronotype, begin to change during the developmental transition from adolescence to college life. The current study examined how these changes related to the sleep/wake patterns of 220 undergraduates (93 males/122 females) ranging in age from 18 to 29 yrs at a private university. Coping strategies students used to deal with early morning commitments and familial conflict over sleep patterns were also examined. Results revealed that evening chronotypes were more likely to report conflict with parents in junior high school and high school over going to bed and waking, followed by a shift to a later sleep/wake pattern in college. They also reported adjusting their schedules and using more coping strate... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415187 Thu, 17 Nov 2011 16:20:08 +0100 5415187 http://www.medworm.com/index.php?rid=5415186&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080736%26dopt%3DAbstract In conclusion, light exposure interpretation requires adjustments for sleep timing among adolescents with DSPD. Pre- and post-sleep light exposures do not appear to contribute directly to phase delays. Sensitivity to morning light may be reduced among adolescents with DSPD. (Author correspondence: auger.raymond1@mayo.edu ). PMID: 22080736 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415186 Thu, 17 Nov 2011 16:19:59 +0100 5415186 http://www.medworm.com/index.php?rid=5415185&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080737%26dopt%3DAbstract Authors: Borisenkov MF Abstract Recently, it was shown that the sleep-wake rhythm of the inhabitants of the temperate zone is entrained to sun time. In the North, significant seasonal changes in the photoperiod may interfere with entrainment of the circadian system to sunlight. This investigation assessed the influence of photoperiod characteristics on the sleep length and sleep-wake rhythm of residents of high latitude. The study was conducted in four towns and six villages located between 59.5?N and 67.6?N latitude between the months of October and May from 2009 through 2011 and included 2822 subjects aged 10 to 97 yrs, 1621 of whom were females and 1201 males. The chronotype and sleep length of the subjects were assessed using the Munich Chronotype Questionnaire. The instruction... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415185 Thu, 17 Nov 2011 16:19:50 +0100 5415185 http://www.medworm.com/index.php?rid=5415184&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080738%26dopt%3DAbstract Authors: Arnulf I, Brion AS, Pottier M, Golmard JL Abstract Cloistered monks and nuns adhere to a 10-century-old strict schedule with a common zeitgeber of a night split by a 2- to 3-h-long Office (Matins). The authors evaluated how the circadian core body temperature rhythm and sleep adapt in cloistered monks and nuns in two monasteries. Five monks and five nuns following the split-sleep night schedule for 5 to 46 yrs without interruption and 10 controls underwent interviews, sleep scales, and physical examination and produced a week-long sleep diary and actigraphy, plus 48-h recordings of core body temperature. The circadian rhythm of temperature was described by partial Fourier time-series analysis (with 12- and 24-h harmonics). The temperature peak and trough values and clock t... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415184 Thu, 17 Nov 2011 16:19:40 +0100 5415184 http://www.medworm.com/index.php?rid=5415183&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080739%26dopt%3DAbstract This study aimed to examine the seasonal variability of retinal detachment (RD) in Taiwan by using an 11-yr nationwide population database. This study also investigated the association of weather conditions, i.e., ambient temperature, relative humidity, rainfall, monthly hours of sunshine, and atmospheric pressure, with RD. Data were retrospectively collected from the Taiwan National Health Insurance Research Database. The study sample included 23 718 RD hospitalizations between January 1999 and December 2009. The incidence rate of RD/100 000 people over the 132 months was computed according to sex and age groupings of <20, 20?39, 40?59, and ?60 yrs. Then, the association between climatic factors and the monthly RD incidence rate was examined. The ARIMA (autoregressive integrated moving... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415183 Thu, 17 Nov 2011 16:19:31 +0100 5415183 http://www.medworm.com/index.php?rid=5415182&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080740%26dopt%3DAbstract Authors: M Ller H, Biermann T, Renk S, Reulbach U, Str Bel A, Kornhuber J, Sperling W Abstract Suicide rate follows a seasonal pattern that is related to rising air temperature and global radiation. These findings are reproducible within different climatic regions. Numerous studies have attempted to explain this peak in relation to weather. However, many of these studies did not use meteorological data representative of the site of the suicide or attempted suicide, resulting in limitations of the findings. Previous studies also suffered from limitations in the methods of data analysis. The current study examined the relationship between weather, i.e., solar radiation, air temperature, and the rate of suicides and suicidality in the area of Mittelfranken, Germany, using regional met... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415182 Thu, 17 Nov 2011 16:19:22 +0100 5415182 http://www.medworm.com/index.php?rid=5415181&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080741%26dopt%3DAbstract In conclusion, the present study confirms diurnal variation of Hcy, selected biological markers of cellular damage, and antioxidant status in young football players. Also, the higher performances and muscle fatigue showed in the evening during RSA exercise might be due to higher levels of biological markers of muscle injury and lower antioxidant status at this TOD. (Author correspondence: n_souissi@yahoo.fr ). PMID: 22080741 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415181 Thu, 17 Nov 2011 16:19:14 +0100 5415181 http://www.medworm.com/index.php?rid=5415180&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080742%26dopt%3DAbstract Authors: Motosugi Y, Ando H, Ushijima K, Maekawa T, Ishikawa E, Kumazaki M, Fujimura A Abstract Recent studies have demonstrated that circadian clocks are impaired in liver and adipose tissue of both leptin-deficient ob/ob and leptin-resistant KK-A(y) mice. Because impairment of peripheral clocks precedes metabolic abnormalities in ob/ob mice, leptin signaling might be important for modulating peripheral clocks. To assess this hypothesis, the authors determined daily mRNA expression profiles of clock genes Clock, Arntl, Per1, Per2, Cry1, Dbp, and Nr1d1 in several tissues of leptin-receptor-deficient Zucker diabetic fatty (ZDF) rats. Transcript levels of some of these genes around the respective peak times decreased significantly in the liver, but not in the suprachiasmatic nucleus,... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415180 Thu, 17 Nov 2011 16:19:05 +0100 5415180 http://www.medworm.com/index.php?rid=5415179&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080784%26dopt%3DAbstract Authors: Bode B, Rossner MJ, Oster H Abstract Many behavioral and physiological processes display diurnal (24-h) rhythms controlled by an internal timekeeping system?the circadian clock. In mammals, a circadian pacemaker is located in the suprachiasmatic nucleus (SCN) of the hypothalamus and synchronizes peripheral oscillators found in most other tissues with the external light-dark (LD) cycle. At the molecular level, circadian clocks are regulated by transcriptional translational feedback loops (TTLs) involving a set of clock genes. The mammalian core TTL includes the transcriptional modulators PER?(1?3) and CRY?(1/2) that inhibit their own expression by interaction with CLOCK/NPAS2 and BMAL1 (ARNTL). The basic helix-loop-helix transcription factors DEC1 (BHLHE40) and DEC2 (BHLHE4... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415179 Tue, 01 Nov 2011 04:00:00 +0100 5415179 http://www.medworm.com/index.php?rid=5415178&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080785%26dopt%3DAbstract Authors: Gomes AA, Tavares J, de Azevedo MH Abstract The present study examined the associations of sleep patterns with multiple measures of academic achievement of undergraduate university students and tested whether sleep variables emerged as significant predictors of subsequent academic performance when other potential predictors, such as class attendance, time devoted to study, and substance use are considered. A sample of 1654 (55% female) full-time undergraduates 17 to 25 yrs of age responded to a self-response questionnaire on sleep, academics, lifestyle, and well-being that was administered at the middle of the semester. In addition to self-reported measures of academic performance, a final grade for each student was collected at the end of the semester. Univariate analyses... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415178 Tue, 01 Nov 2011 04:00:00 +0100 5415178 http://www.medworm.com/index.php?rid=5415177&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080786%26dopt%3DAbstract In conclusion, in daytime workers, a morning-type orientation and more stable sleep timing are associated with better subjective sleep quality. (Author correspondence: asoehner@berkeley.edu ). PMID: 22080786 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415177 Tue, 01 Nov 2011 04:00:00 +0100 5415177 http://www.medworm.com/index.php?rid=5415176&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080787%26dopt%3DAbstract In conclusion, for the day-shift workers, a higher cortisol response was observed on workdays compared to off days. Although no direct comparisons could be made between groups for work days, on off days the irregular-shift workers had higher cortisol levels compared to day-shift workers, suggesting a prolonged stress response in the irregular-shift group. In addition, cortisol levels were correlated with stressors and metabolic parameters. Future studies are warranted to investigate further stress responses in the context of irregular work hours. (Author correspondence: crmoreno@usp.br ). PMID: 22080787 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415176 Tue, 01 Nov 2011 04:00:00 +0100 5415176 http://www.medworm.com/index.php?rid=5415175&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080788%26dopt%3DAbstract Authors: Basta NO, James PW, Craft AW, McNally RJ Abstract Infection with human papillomavirus is an established risk factor for cervical carcinoma. However, the role of other environmental factors is less well established. To further investigate whether other agents may be involved, the authors have analyzed seasonal variation in cervical cancer with respect to month of birth and separately month of diagnosis. All 85 cases diagnosed in 15?24-yr-olds during the period 1968?2005 were extracted from the specialist population-based Northern Region Young Persons' Malignant Disease Registry. The chi-square heterogeneity test was used to assess overall nonuniform variation in month of birth and separately month of diagnosis. Poisson regression analysis was used to fit sinusoidal (harmoni... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415175 Tue, 01 Nov 2011 04:00:00 +0100 5415175 http://www.medworm.com/index.php?rid=5415174&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22080789%26dopt%3DAbstract In conclusion, these data suggest that CLOCK does not play a major role in the pathophysiology of mood disorders. (Author correspondence: tarok@fujita-hu.ac.jp ). PMID: 22080789 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5415174 Tue, 01 Nov 2011 04:00:00 +0100 5415174 http://www.medworm.com/index.php?rid=5241954&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21929297%26dopt%3DAbstract Authors: Stevens RG PMID: 21929297 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5241954 Thu, 22 Sep 2011 21:29:13 +0100 5241954 http://www.medworm.com/index.php?rid=5241953&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21929298%26dopt%3DAbstract Authors: Brager AJ, Prosser RA, Glass JD Abstract The PER2 clock gene modulates ethanol consumption, such that mutant mice not expressing functional mPer2 have altered circadian behavior that promotes higher ethanol intake and preference. Experiments were undertaken to characterize circadian-related behavioral effects of mPer2 deletion on ethanol intake and to explore how acamprosate (used to reduce alcohol dependence) alters diurnal patterns of ethanol intake. Male mPer2 mutant and WT (wild-type) mice were entrained to a 12:12 h light-dark (12L:12D) photocycle, and their locomotor and drinking activities were recorded. Circadian locomotor measurements confirmed that mPer2 mutants had an advanced onset of nocturnal activity of about 2 h relative to WTs, and an increased duratio... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5241953 Thu, 22 Sep 2011 21:29:03 +0100 5241953 http://www.medworm.com/index.php?rid=5241952&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21929299%26dopt%3DAbstract In conclusion, changes in melatonin level and CBT were intact in older poor sleepers in that evening melatonin increased and CBT decreased. However, poor sleepers showed a weaker evening increase in melatonin level, and their DLMO was delayed compared with good sleepers, suggesting that it is not primarily the absolute level of endogenous melatonin, but rather the timing of the circadian rhythm in evening melatonin secretion that might be related to disturbances in the sleep-wake cycle in older people. (Author correspondence: mdittmar@zoologie.uni-kiel.de ). PMID: 21929299 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5241952 Thu, 22 Sep 2011 21:28:53 +0100 5241952 http://www.medworm.com/index.php?rid=5241951&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21929300%26dopt%3DAbstract Authors: Riedel M, Berrez S, Pelisse D, Brousse E, Forget C, Marlot M, Smolensky MH, Touitou Y, Reinberg A Abstract The first aim of the study was to assess clock-time patterning of work-related injuries (WRIs) of firemen (FM) of Saône et Loire-71 (France) during the 4-yr span of 1 January 2004 to 31 December 2007. FM of this service are legally required to log every WRI and seek its evaluation by the medical service, whether the WRI was the result of worksite duties or exercise/sport activities at the station. WRI was defined specifically as a (nonexercise, nonsport, and nonemotional/stress) work-associated trauma, verified both by log book and medical records. For the corresponding years, the 24-h pattern of emergency calls (Calls) plus road traffic (Traffic) on the main roads o... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5241951 Thu, 22 Sep 2011 21:28:42 +0100 5241951 http://www.medworm.com/index.php?rid=5241950&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21929301%26dopt%3DAbstract Authors: Portaluppi F, Fabbian F, Manfredini F, Manfredini R PMID: 21929301 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5241950 Thu, 22 Sep 2011 21:28:32 +0100 5241950 http://www.medworm.com/index.php?rid=5241949&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21929302%26dopt%3DAbstract Authors: Rowland T PMID: 21929302 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5241949 Thu, 22 Sep 2011 21:28:21 +0100 5241949 http://www.medworm.com/index.php?rid=5241948&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21929303%26dopt%3DAbstract LAN and Breast Cancer Risk: Can We See a Forest Through the Trees?-Response to "Measurements of Light at Night (LAN) for a Sample of Female School Teachers" by M. S. Rea, J. A. Brons, and M. G. Figueiro. Chronobiol Int. 2011 Oct.;28(8):734-736 Authors: Haim A, Portnov BA PMID: 21929303 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5241948 Thu, 22 Sep 2011 21:28:11 +0100 5241948 http://www.medworm.com/index.php?rid=5225911&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21919721%26dopt%3DAbstract Authors: Osland TM, Bjorvatn B, Steen VM, Pallesen S Abstract Circadian rhythms are endogenously generated cycles involving physiological parameters, such as core body temperature, hormone levels, blood pressure, sleep, and metabolism, with a period length of around 24 h. The circadian clock in mammals is regulated by a set of clock genes that are functionally linked together, and polymorphisms in clock genes could be associated with differences in circadian rhythms. A variable-number tandem repeat (VNTR) in the human clock gene PERIOD3 (PER3) has been suggested to correlate with a morning (lark) versus evening (owl) chronotype as well as with the circadian rhythm sleep disorder "delayed sleep phase disorder" (DSPD). The authors examined 432 healthy Norwegian university students ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5225911 Thu, 15 Sep 2011 04:00:00 +0100 5225911 http://www.medworm.com/index.php?rid=5216189&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895489%26dopt%3DAbstract Authors: Levandovski R, Dantas G, Fernandes LC, Caumo W, Torres I, Roenneberg T, Hidalgo MP, Allebrandt KV Abstract In public health, mood disorders are among the most important mental impairments. Patients with depressive episodes exhibit daily mood variations, abnormal patterns in sleep-wake behavior, and in the daily rhythms of several endocrine-metabolic parameters. Although the relationship between the sleep/circadian processes and mood disorders is poorly understood, clock-related therapies, such as light therapy, sleep deprivation, and rigid sleep schedules, have been shown to be effective treatments. Several studies investigated the relationship between circadian phenotype (chronotype) and depression. These focused mainly on urban populations and assessed diurnal preference... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5216189 Tue, 06 Sep 2011 04:00:00 +0100 5216189 http://www.medworm.com/index.php?rid=5216188&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21895490%26dopt%3DAbstract Authors: Vera LM, Al-Khamees S, Hervé M Abstract The effect of stocking density on the locomotor activity of African catfish C. gariepinus under different light regimes was investigated. C. gariepinus were stocked under different densities (1, 5, or 10 fish/tank), and their locomotor activity recorded under light-dark (LD), constant light (LL), constant darkness (DD), and LD-reversed (DL) regimens. Under the LD cycle, catfish showed a crepuscular activity pattern, irrespective of stocking density, with most of the daily activity concentrated around the light-onset and light-offset times. When fish were subjected to DD, all 4 tanks with medium (5 fish) and high (10 fish) stocking densities showed circadian rhythmicity, with an average period (τ) of 23.3 ± 0.5 and 24.6 ± ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5216188 Tue, 06 Sep 2011 04:00:00 +0100 5216188 http://www.medworm.com/index.php?rid=5191068&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21877941%26dopt%3DAbstract This study investigated whether changes in illumination modify perception of day and night conditions in a diurnal species, the Indian weaver bird. Birds were initially subjected to a 12-h light:12-h dark regime (12L:12D; L = 20 lux, D = 0.5 lux). After every 2 wks, the combinations of light illumination in L and D phases were changed as follows: 20:2 lux, 20:5 lux, 20:10 lux, 20:20 lux, 20:100 lux, and 20:200 lux. Finally, birds were released into dim constant light (0.5 lux) for 2 wks to determine the phase and period of the circadian activity rhythm. They were also laparotomized at periodic intervals to examine the effects of the light regimes on the seasonal testicular cycle. All individuals showed a consistently similar response. As evident by the activity pattern under these li... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5191068 Mon, 29 Aug 2011 23:00:00 +0100 5191068 http://www.medworm.com/index.php?rid=5171982&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21867367%26dopt%3DAbstract Authors: Rea MS, Brons JA, Figueiro MG Abstract Epidemiological studies have shown an association between rotating shiftwork and breast cancer (BC) risk. Recently, light at night (LAN) measured by satellite photometry and by self-reports of bedroom brightness has been shown to be associated with BC risk, irrespective of shiftwork history. Importance has been placed on these associations because retinal light exposures at night can suppress the hormone melatonin and/or disrupt circadian entrainment to the local 24-h light-dark cycle. The present study examined whether it was valid to use satellite photometry and self-reports of brightness to characterize light, as it might stimulate the circadian system and thereby affect BC incidence. Calibrated photometric measurements were made a... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5171982 Wed, 24 Aug 2011 23:00:00 +0100 5171982 http://www.medworm.com/index.php?rid=5171981&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21867369%26dopt%3DAbstract In conclusion, the time-in-bed reduction in the period analyzed cannot be considered to be a mediating factor to modifications in overweight anthropometric indicators. (Author correspondence: michelleb_fisio@yahoo.com.br ). PMID: 21867369 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5171981 Wed, 24 Aug 2011 23:00:00 +0100 5171981 http://www.medworm.com/index.php?rid=5140049&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21834641%26dopt%3DAbstract Authors: Koletar MM, Cheng HY, Penninger JM, Ralph MR Abstract Loss of Dexras1 in gene-targeted mice impairs circadian entrainment to light cycles and produces complex changes to phase-dependent resetting responses (phase shifts) to light. The authors now describe greatly enhanced and phase-specific nonphotic responses induced by arousal in dexras1(-/-) mice. In constant conditions, mutant mice exhibited significant arousal-induced phase shifts throughout the subjective day. Unusual phase advances in the late subjective night were also produced when arousal has little effect in mice. Bilateral lesions of the intergeniculate leaflet (IGL) completely eliminated both the nonphotic as well as the light-induced phase shifts of circadian locomotor rhythms during the subjective day, but ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5140049 Wed, 10 Aug 2011 23:00:00 +0100 5140049 http://www.medworm.com/index.php?rid=5140054&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21819347%26dopt%3DAbstract Authors: Harada T, Kobayashi R, Wada K, Nishihara R, Kondo A, Akimitsu O, Noji T, Taniwaki N, Nakade M, Krejci M, Takeuchi H Abstract Several studies suggest that season of birth differentially affects the physiological characteristics of humans. Those living at relatively high latitude, such as Canada, Spain, and Italy (44°N-45°N), and born in the fall tended to be "morning-type" persons in comparison to those born in other seasons. There are relatively little data on the affect of season of birth on people residing at low latitude. Here the authors show that at low latitude, Kochi, Japan (33°N), the effect of season of birth on the morningness chronotype is confined to young children aged 1-12 yrs, disappearing in elderly persons. Only female participants aged 2-12 yrs born in... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5140054 Sun, 07 Aug 2011 23:00:00 +0100 5140054 http://www.medworm.com/index.php?rid=5140053&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21823816%26dopt%3DAbstract Authors: Darwent D, Zhou X, Heuvel CV, Sargent C, Roach GD Abstract The human core body temperature (CBT) rhythm is tightly coupled to an endogenous circadian pacemaker located in the suprachiasmatic nucleus of the anterior hypothalamus. The standard method for assessing the status of this pacemaker is by continuous sampling of CBT using rectal thermometry. This research sought to validate the use of ingestible, temperature-sensitive capsules to measure CBT as an alternative to rectal thermometry. Participants were 11 young adult males who had volunteered to complete a laboratory protocol that extended across 12 consecutive days. A total of 87 functional capsules were ingested and eliminated by participants during the laboratory internment. Core body temperature samples were collec... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5140053 Sun, 07 Aug 2011 23:00:00 +0100 5140053 http://www.medworm.com/index.php?rid=5140052&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21823817%26dopt%3DAbstract Authors: Molina TA, Burgess HJ Abstract The dim light melatonin onset (DLMO) is the most reliable circadian phase marker in humans, but the cost of assaying samples is relatively high. Therefore, the authors examined differences between DLMOs calculated from hourly versus half-hourly sampling and differences between DLMOs calculated with two recommended thresholds (a fixed threshold of 3 pg/mL and a variable "3k" threshold equal to the mean plus two standard deviations of the first three low daytime points). The authors calculated these DLMOs from salivary dim light melatonin profiles collected from 122 individuals (64 women) at baseline. DLMOs derived from hourly sampling occurred on average only 6-8 min earlier than the DLMOs derived from half-hourly saliva sampling, and they w... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5140052 Sun, 07 Aug 2011 23:00:00 +0100 5140052 http://www.medworm.com/index.php?rid=5140051&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21823818%26dopt%3DAbstract Authors: Shackelford J PMID: 21823818 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5140051 Sun, 07 Aug 2011 23:00:00 +0100 5140051 http://www.medworm.com/index.php?rid=5140050&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21823969%26dopt%3DAbstract Authors: Hermida RC, Ayala DE, Mojón A, Fontao MJ, Fernández JR Abstract Administration of angiotensin receptor blockers at bedtime results in greater reduction of nighttime blood pressure than dosing upon awakening, independent of the terminal half-life of each individual medication. To obtain blood pressure (BP) target goals most patients require treatment with more than one hypertension medication. However, the potential differing effects on BP regulation of combination therapy depending on the time-of-day of administration have scarcely been investigated. Accordingly, the authors prospectively evaluated the administration-time-dependent BP-lowering efficacy of valsartan/hydrochlorothiazide (HCTZ) combination therapy. The authors conducted a randomized, open-label, blinded-end... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5140050 Sun, 07 Aug 2011 23:00:00 +0100 5140050 http://www.medworm.com/index.php?rid=5092923&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21793668%26dopt%3DAbstract Authors: Natale V, Milia LD The present study explored the possible role of the photoperiod at birth on morningness by collecting data in the northern (Italy) and southern (Australia) hemispheres. To assess circadian typology, the Composite Scale of Morningness (CS) was administered to a sample of 1734 university students (977 Italian and 757 Australian; 1099 females and 635 males; age 24.79 ± 7.45 yrs [mean ± SD]). Consistent with the literature, females reported higher CS scores (morningness) than males, and Australian participants reported higher CS scores than Italian participants. Allowing for the fact the seasons are reversed between the hemispheres, the results are in line with previous studies. The authors found more evening types were born during the seasons associat... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092923 Tue, 26 Jul 2011 23:00:00 +0100 5092923 http://www.medworm.com/index.php?rid=5092919&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21793691%26dopt%3DAbstract Authors: Muro A, Gomà-I-Freixanet M, Adan A, Cladellas R Research on personality and circadian typology indicates evening-type women are more impulsive and novelty seeking, neither types are more anxious, and morning types tend to be more active, conscientious, and persistent. The purpose of this study is to examine the differences between circadian typologies in the light of the Zuckerman's Alternative Five-Factor Model (AFFM) of personality, which has a strong biological basis, in an adult sample of 412 women 18 to 55 yrs of age. The authors found morning-type women had significant higher scores than evening-type and neither-type women on Activity, and its subscales General Activity and Work Activity. In contrast, evening-type women scored significantly higher than morning-type wome... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092919 Tue, 26 Jul 2011 23:00:00 +0100 5092919 http://www.medworm.com/index.php?rid=5092915&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21793693%26dopt%3DAbstract Authors: Martinez-Nicolas A, Ortiz-Tudela E, Madrid JA, Rol MA Daily exposure to environmental light is the most important zeitgeber in humans, and all studied characteristics of light pattern (timing, intensity, rate of change, duration, and spectrum) influence the circadian system. However, and due to lack of current studies on environmental light exposure and its influence on the circadian system, the aim of this work is to determine the characteristics of a naturalistic regimen of light exposure and its relationship with the functioning of the human circadian system. Eighty-eight undergraduate students (18-23 yrs) were recruited in Murcia, Spain (latitude 38°01'N) to record wrist temperature (WT), light exposure, and sleep for 1 wk under free-living conditions. Light-exposure timi... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092915 Tue, 26 Jul 2011 23:00:00 +0100 5092915 http://www.medworm.com/index.php?rid=5092911&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21793694%26dopt%3DAbstract Authors: Chtourou H, Zarrouk N, Chaouachi A, Dogui M, Behm DG, Chamari K, Hug F, Souissi N The present study was designed to evaluate time-of-day effects on electromyographic (EMG) activity changes during a short-term intense cycling exercise. In a randomized order, 22 male subjects were asked to perform a 30-s Wingate test against a constant braking load of 0.087 kg·kg(-1) body mass during two experimental sessions, which were set up either at 07:00 or 17:00 h. During the test, peak power (P(peak)), mean power (P(mean)), fatigue index (FI; % of decrease in power output throughout the 30 s), and evolution of power output (5-s span) throughout the exercise were analyzed. Surface EMG activity was recorded in both the vastus lateralis and vastus medialis muscles throughout the test a... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092911 Tue, 26 Jul 2011 23:00:00 +0100 5092911 http://www.medworm.com/index.php?rid=5092907&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21793695%26dopt%3DAbstract Authors: Pendergast JS, Yamazaki S Masking is an acute effect of an external signal on an overt rhythm and is distinct from the process of entrainment. In the current study, we investigated the phase dependence and molecular mechanisms regulating masking effects of light pulses on spontaneous locomotor activity in mice. The circadian genes, Period1 (Per1) and Per2, are necessary components of the timekeeping machinery and entrainment by light appears to involve the induction of the expression of Per1 and Per2 mRNAs in the suprachiasmatic nuclei (SCN). We assessed the roles of the Per genes in regulating masking by assessing the effects of light pulses on nocturnal locomotor activity in C57BL/6J Per mutant mice. We found that Per1(-/-) and Per2(-/-) mice had robust negative masking resp... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092907 Tue, 26 Jul 2011 23:00:00 +0100 5092907 http://www.medworm.com/index.php?rid=5092930&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21790327%26dopt%3DAbstract Authors: van der Veen DR, Saaltink DJ, Gerkema MP Light is the main entraining signal of the central circadian clock, which drives circadian organization of activity. When food is made available during only certain parts of the day, it can entrain the clock in the liver without changing the phase of the central circadian clock. Although a hallmark of food entrainment is a behavioral anticipation of food availability, the extent of behavioral alterations in response to food availability has not been fully characterized. The authors have investigated interactions between light and temporal food availability in the timing of activity in the common vole. Temporally restricted food availability enhanced or attenuated re-entrainment to a phase advance in light entrainment when it was shifted... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092930 Mon, 25 Jul 2011 23:00:00 +0100 5092930 http://www.medworm.com/index.php?rid=5092926&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21790328%26dopt%3DAbstract This study was designed to examine time-of-day effects on markers of cardiac functional capacity during a standard progressive cycle exercise test. Fourteen healthy, untrained young males (mean ± SD: 17.9 ± 0.7 yrs of age) performed identical maximal cycle tests in the morning (08:00-11:00 h) and late afternoon (16:00-19:00 h) in random order. Cardiac variables were measured at rest, submaximal exercise, and maximal exercise by standard echocardiographic techniques. No differences in morning and afternoon testing values at rest or during exercise were observed for oxygen uptake, heart rate, cardiac output, or markers of systolic and diastolic myocardial function. Values at peak exercise for Vo(2) at morning and afternoon testing were 3.20 ± 0.49 and 3.24 ± 0.55 L ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092926 Mon, 25 Jul 2011 23:00:00 +0100 5092926 http://www.medworm.com/index.php?rid=5092938&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21777116%26dopt%3DAbstract This study also provides indications, though arguably not conclusive evidence, that in either case the neuronal mechanisms follow a signal-transduction pathway in which Ca(2+) and cAMP may act as the intracellular messengers. It also appears that proteasomal proteolysis is a conserved event in the regulation of AANAT activity in vertebrates. (Author correspondence: dgp_skmaitra@yahoo.co.in ). PMID: 21777116 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092938 Wed, 20 Jul 2011 23:00:00 +0100 5092938 http://www.medworm.com/index.php?rid=5092934&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21777120%26dopt%3DAbstract In conclusion, we did not find significant association between MOB and risk of lung cancer in our total sample (although results alluded to a weak association between MOB and risk of lung cancer development among males). The possible associations between MOB and the risk of lung cancer development (or smoking) would require confirmation (or refutation) in large studies from other populations. (Author correspondence: dome_peter@yahoo.co.uk ). PMID: 21777120 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092934 Wed, 20 Jul 2011 23:00:00 +0100 5092934 http://www.medworm.com/index.php?rid=5092901&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797776%26dopt%3DAbstract Authors: Chu G, Yoshida K, Narahara S, Uchikawa M, Kawamura M, Yamauchi N, Xi Y, Shigeyoshi Y, Hashimoto S, Hattori MA Ovarian development is related to cell proliferation, differentiation, and apoptosis of granulosa cells and luteal cells under the control of various modulators, including follicle-stimulating hormone (FSH), luteinizing hormone (LH), and growth factors. In the present study, the expression of clock genes and the related regulation mechanism were analyzed in different ovarian cell types during differentiation and apoptosis. The authors focused on the circadian expression of Per2 as a core clock gene for the maintenance of circadian rhythms. By using a real-time monitoring system of the Per2 promoter activity, the circadian oscillation was analyzed in the granulosa and l... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092901 Thu, 30 Jun 2011 23:00:00 +0100 5092901 http://www.medworm.com/index.php?rid=5092896&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797777%26dopt%3DAbstract Authors: Evans JA, Elliott JA, Gorman MR The endogenous circadian pacemaker of mammals is synchronized to the environmental day by the ambient cycle of relative light and dark. The present studies assessed the actions of light in a novel circadian entrainment paradigm where activity rhythms are bifurcated following exposure to a 24-h light:dark:light:dark (LDLD) cycle. Bifurcated entrainment under LDLD reflects the temporal dissociation of component oscillators that comprise the circadian system and is facilitated when daily scotophases are dimly lit rather than completely dark. Although bifurcation can be stably maintained in LDLD, it is quickly reversed under constant conditions. Here the authors examine whether dim scotophase illumination acts to maintain bifurcated entrainment unde... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092896 Thu, 30 Jun 2011 23:00:00 +0100 5092896 http://www.medworm.com/index.php?rid=5092893&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797778%26dopt%3DAbstract Authors: Lone SR, Sadanandappa MK, Sharma VK Circadian clocks use a wide range of environmental cues, including cycles of light, temperature, food, and social interactions, to fine-tune rhythms in behavior and physiology. Although social cues have been shown to influence circadian clocks of a variety of organisms including the fruit fly Drosophila melanogaster, their mechanism of action is still unclear. Here, the authors report the results of their study aimed at investigating if daily cycles of presence and absence (PA) of conspecific male visitors are able to entrain the circadian locomotor activity rhythm of male hosts living under constant darkness (DD). The results suggest that PA cycles may not be able to entrain circadian locomotor activity rhythms of Drosophila. The outcome do... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092893 Thu, 30 Jun 2011 23:00:00 +0100 5092893 http://www.medworm.com/index.php?rid=5092890&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797779%26dopt%3DAbstract Authors: Hermida RC, Chayán L, Ayala DE, Mojón A, Fontao MJ, Fernández JR There is a strong association between metabolic syndrome (MS) and increased cardiovascular risk. Moreover, elevated nighttime blood pressure (BP) and non-dipping (subjects with <10% decline in the asleep relative to the awake BP mean) have been also linked to increased cardiovascular morbidity and mortality. We investigated the relation between MS, circadian time of hypertension treatment, and impaired nighttime BP decline in a cross-sectional study on 3352 (1576 men/1776 women) non-diabetic hypertensive subjects, 53.7 ± 13.1 (mean ± SD) yrs of age. Among them, 2056 were ingesting all their prescribed hypertension medication upon awakening, and 1296 were ingesting at least one of their BP medicati... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092890 Thu, 30 Jun 2011 23:00:00 +0100 5092890 http://www.medworm.com/index.php?rid=5092885&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797780%26dopt%3DAbstract Authors: Taillard J, Philip P, Claustrat B, Capelli A, Coste O, Chaumet G, Sagaspe P The aim of the study was to evaluate the influence of chronotype (morning-type versus evening-type) living in a fixed sleep-wake schedule different from one's preferred sleep schedules on the time course of neurobehavioral performance during controlled extended wakefulness. The authors studied 9 morning-type and 9 evening-type healthy male subjects (21.4 ± 1.9 yrs). Before the experiment, all participants underwent a fixed sleep-wake schedule mimicking a regular working day (bedtime: 23:30 h; wake time: 07:30 h). Then, following two nights in the laboratory, both chronotypes underwent a 36-h constant routine, performing a cognitive test of sustained attention every hour. Core body temperature,... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092885 Thu, 30 Jun 2011 23:00:00 +0100 5092885 http://www.medworm.com/index.php?rid=5092882&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797781%26dopt%3DAbstract Authors: Puttonen S, Viitasalo K, Härmä M Shiftwork is associated with an increased risk of cardiovascular diseases, but the possible role of inflammation in this relationship is not well known. We tested the hypothesis that shiftwork would be associated with higher levels of C-reactive protein (CRP) and increased leukocyte count. We analyzed the cross-sectional associations between work arrangements and low-grade inflammation in 1877 airline-company employees separately for men (n = 1037) and women (n = 840). The participants were classified into five categories according to their work schedule: day workers who have not worked in shifts (referent group), former shiftworkers, 2-shift workers, 3-shift workers, and in-flight workers. In models adjusted for age and recent infect... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092882 Thu, 30 Jun 2011 23:00:00 +0100 5092882 http://www.medworm.com/index.php?rid=5092850&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797782%26dopt%3DAbstract Authors: Tonetti L, Fabbri M, Martoni M, Natale V The aim of the present study was to explore the relationship between season of birth and sleep-timing preferences in adolescence. To this end, the Morningness-Eveningness Questionnaire for Children and Adolescents (MEQ-CA) was administered to 1912 adolescents (1058 females and 854 males), ranging in age between 10 and 17 yrs. To assess preferred sleep habits, the authors considered the answers to the open-ended questions of the MEQ-CA (items 1 and 2), regarding the preferred arising time and the preferred going to bed time. Combining the answers to these two questions, the authors also indirectly computed the preferred sleep duration and preferred midpoint of sleep. Season of birth did not significantly modulate the overall MEQ-CA score... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092850 Thu, 30 Jun 2011 23:00:00 +0100 5092850 http://www.medworm.com/index.php?rid=5092840&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797783%26dopt%3DAbstract Authors: Taylor DJ, Clay KC, Bramoweth AD, Sethi K, Roane BM The current study offers a comprehensive assessment of psychosocial functioning and academic performance in relation to circadian phase preference in a US sample of undergraduate college students (N = 838), aged 17-26 (M = 19.78, SD = 1.89). Women had greater morning preference than men, and seniors had greater morning preference than freshmen. Circadian phase preference, fatigue, perceived stress, depression, anxiety, and substance use were assessed cross-sectionally and grade point average (GPA) was assessed prospectively. Evening phase preference was related to higher levels of fatigue, alcohol and caffeine use, and worse academic performance than morning or intermediate phase preferences. (Author correspondenc... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092840 Thu, 30 Jun 2011 23:00:00 +0100 5092840 http://www.medworm.com/index.php?rid=5092823&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797784%26dopt%3DAbstract CORRIGENDUM. Chronobiol Int. 2011 Jul.;28(6):548-550 Authors: PMID: 21797784 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092823 Thu, 30 Jun 2011 23:00:00 +0100 5092823 http://www.medworm.com/index.php?rid=5092792&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797785%26dopt%3DAbstract Authors: PMID: 21797785 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=5092792 Thu, 30 Jun 2011 23:00:00 +0100 5092792 http://www.medworm.com/index.php?rid=4998020&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721853%26dopt%3DAbstract Authors: Patiño MA, Rodríguez-Illamola A, Conde-Sieira M, Soengas JL, Míguez JM Living organisms show daily rhythms in physiology, behavior, and gene expression, which are due to the presence of endogenous clocks that synchronize biological processes to the 24-h light/dark cycle. In metazoans, generation of circadian rhythmicity is a consequence of specialized tissues known as "master clocks," having different locations among species. A few studies have described clock-gene expression in fish neural tissues, but none of them assessed clock-gene expression in different discrete regions. The present study was designed to explore the presence/absence of circadian clock-gene expression in the rainbow trout (Oncorhynchus mykiss) retina and hypothalamus. Juvenile fish were acclimated to a... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998020 Sat, 30 Apr 2011 23:00:00 +0100 4998020 http://www.medworm.com/index.php?rid=4998019&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721854%26dopt%3DAbstract Authors: Thakurdas P, Sharma S, Singh B, Vanlalhriatpuia K, Joshi D Photic entrainment of animals in the field is basically attributed to their exposure to the dimly lit nights flanked by the dawn and dusk twilight transitions. This implicates the functional significance of the dimly lit nights as that of the twilight transitions. Recently, the authors have demonstrated that the dimly lit night at 0.0006 lux altered the attributes of the circadian rhythm of locomotor activity of Drosophila jambulina. The present study examined whether the durations of such dimly lit nights affect the entrainment and free-running rhythmicity of D. jambulina. Flies were subjected for 10 days to two types of 24-h lighting regimes in which the photophase (L) was at 10 lux for all flies but the scotophase, ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998019 Sat, 30 Apr 2011 23:00:00 +0100 4998019 http://www.medworm.com/index.php?rid=4998018&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721855%26dopt%3DAbstract This study provides valuable new insights in our understanding of the circadian modulation of alcohol-induced behaviors that ultimately could facilitate preventative measures in combating alcohol abuse and alcoholism. (Author correspondence: lyons@bio.fsu.edu ). PMID: 21721855 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998018 Sat, 30 Apr 2011 23:00:00 +0100 4998018 http://www.medworm.com/index.php?rid=4998017&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721856%26dopt%3DAbstract This study investigates the possibility of an endogenous circadian rhythm in retinal cone function in humans. A full-field cone electroretinogram (ERG) was performed every 2 h for 24 h under continuous rod-saturating ambient white light (53 ± 30 lux; pupils dilated) in nine healthy subjects. Distinct circadian variations were superimposed upon a gradual decrease in cone responsiveness to light, demonstrated most reliably in the implicit times of b-wave and oscillatory potentials, and to a lesser extent in amplitude and a-wave implicit times. After mathematical correction of the linear trend, the cone response was found to be greatest around 20:00 h and least around 06:00 h. The phase of the ERG circadian rhythm was not synchronized with the phase of the salivary melatonin rhythm... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998017 Sat, 30 Apr 2011 23:00:00 +0100 4998017 http://www.medworm.com/index.php?rid=4998016&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721857%26dopt%3DAbstract Authors: Parry BL, Meliska CJ, Sorenson DL, Martínez LF, López AM, Elliott JA, Hauger RL The authors previously observed blunted phase-shift responses to morning bright light in women with premenstrual dysphoric disorder (PMDD). The aim of this study was to determine if these findings could be replicated using a higher-intensity, shorter-duration light pulse and to compare these results with the effects of an evening bright-light pulse. In 17 PMDD patients and 14 normal control (NC) subjects, the authors measured plasma melatonin at 30-min intervals from 18:00 to 10:00 h in dim (<30 lux) or dark conditions the night before (Night 1) and after (Night 3) a bright-light pulse (administered on Night 2) in both follicular and luteal menstrual cycle phases. The bright light (either 30... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998016 Sat, 30 Apr 2011 23:00:00 +0100 4998016 http://www.medworm.com/index.php?rid=4998015&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721858%26dopt%3DAbstract Authors: Corbalán-Tutau MD, Madrid JA, Ordovás JM, Smith CE, Nicolás F, Garaulet M The circadian rhythm of core body temperature is associated with widespread physiological effects. However, studies with other more practical temperature measures, such as wrist (WT) and proximal temperatures, are still scarce. The aim of this study was to investigate whether obesity is associated with differences in mean WT values or in its daily rhythmicity patterns. Daily patterns of cortisol, melatonin, and different metabolic syndrome (MetS) features were also analyzed in an attempt to clarify the potential association between chronodisruption and MetS. The study was conducted on 20 normal-weight women (age: 38 ± 11 yrs and BMI: 22 ± 2.6 kg/m(2)) and 50 obese women (age: 42 ± 10 ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998015 Sat, 30 Apr 2011 23:00:00 +0100 4998015 http://www.medworm.com/index.php?rid=4998014&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721859%26dopt%3DAbstract This study shows that an 8.5-h exposure to mild hypoxia is able to alter very quickly the 24-h pattern of iron and ferritin. These alterations seem to depend, at least in part, on the clinical tolerance to hypoxia and may help explain the interindividual differences observed in the tolerance to hypoxia. (Author correspondence: yvan.touitou@chronobiology.fr ). PMID: 21721859 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998014 Sat, 30 Apr 2011 23:00:00 +0100 4998014 http://www.medworm.com/index.php?rid=4998013&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721860%26dopt%3DAbstract This study examined the effects of long- and short-term shiftwork on the cortisol awakening response among officers (n = 68) in the Buffalo Cardio-Metabolic Occupational Police Stress (BCOPS) pilot study (2001-2003). The time each officer spent on day (start time: 04:00-11:59 h), afternoon (12:00-19:59 h), or night (20:00-03:59 h) shifts was summarized from 1994 to examination date to characterize long-term (mean: 14 ± 9 yrs) and short-term (3, 5, 7, or 14 days prior to participation) shiftwork exposures. The cortisol awakening response was characterized by summarizing the area under the curve (AUC) for samples collected on first awakening, and at 15-, 30-, and 45-min intervals after waking. Data were collected on a scheduled training or off day. The cortisol AUC with respect to gro... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998013 Sat, 30 Apr 2011 23:00:00 +0100 4998013 http://www.medworm.com/index.php?rid=4998012&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721861%26dopt%3DAbstract This study shows that the circadian timing system represents an important toxicity target of irinotecan in female mice, where circadian disruption persists after wrongly timed treatment. As a result, the mechanisms underling cancer chronotherapeutics are expectedly more susceptible to disruption in females as compared to males. Thus, the optimal circadian timing of chemotherapy requires precise determination according to sex, and should involve the noninvasive monitoring of circadian biomarkers. (Author correspondence: francis.levi@inserm.fr ). PMID: 21721861 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998012 Sat, 30 Apr 2011 23:00:00 +0100 4998012 http://www.medworm.com/index.php?rid=4998011&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721862%26dopt%3DAbstract Authors: Erren TC, Groß JV, Meyer-Rochow VB PMID: 21721862 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998011 Sat, 30 Apr 2011 23:00:00 +0100 4998011 http://www.medworm.com/index.php?rid=4998010&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721863%26dopt%3DAbstract Authors: Borisenkov MF PMID: 21721863 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998010 Sat, 30 Apr 2011 23:00:00 +0100 4998010 http://www.medworm.com/index.php?rid=4998009&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721864%26dopt%3DAbstract Authors: Kawada T PMID: 21721864 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998009 Sat, 30 Apr 2011 23:00:00 +0100 4998009 http://www.medworm.com/index.php?rid=4998008&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721865%26dopt%3DAbstract Authors: Driesen K, Jansen NW, Kant I, Mohren DC, van Amelsvoort LG PMID: 21721865 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4998008 Sat, 30 Apr 2011 23:00:00 +0100 4998008 http://www.medworm.com/index.php?rid=4798616&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539420%26dopt%3DAbstract Authors: Putilov AA Sleep-wake regulation involves reciprocal interactions between sleep- and wake-promoting processes that inhibit one another. To uncover the signatures of the opponent processes underlying ultradian sleep cycles, principal component analysis was performed on the sets of 16 single-Hz log-transformed electroencephalographic (EEG) power densities (1-16 Hz frequency range). Data were collected during unrestricted night sleep followed by 9 20-min naps (14 women aged 17-55 yrs) and during 12 20-min naps after either restriction or deprivation of sleep (9 males and 9 males, respectively, aged 18-22 yrs). It was found that any subset of power spectra could be reduced to the invariant four-principal component structure. The time courses of scores on these four components mi... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798616 Sat, 30 Apr 2011 23:00:00 +0100 4798616 http://www.medworm.com/index.php?rid=4798615&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539421%26dopt%3DAbstract Authors: Blanco-Vives B, Aliaga-Guerrero M, Cañavate JP, Muñoz-Cueto JA, Sánchez-Vázquez FJ Light plays a key role in the development of biological rhythms in fish. Previous research on Senegal sole has revealed that both spawning rhythms and larval development are strongly influenced by lighting conditions. However, hatching rhythms and the effect of light during incubation are as yet unexplored. Therefore, the aim of this study was to investigate the impact of the light spectrum and photoperiod on Solea senegalensis eggs and larvae until day 7 post hatching (dph). To this end, eggs were collected immediately after spawning during the night and exposed to continuous light (LL), continuous darkness (DD), or light-dark (LD) 12L:12D cycles of white light (LD(W)), blue light (LD(B); �... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798615 Sat, 30 Apr 2011 23:00:00 +0100 4798615 http://www.medworm.com/index.php?rid=4798614&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539422%26dopt%3DAbstract Authors: Tran D, Nadau A, Durrieu G, Ciret P, Parisot JP, Massabuau JC The present study reports new insights into the complexity of environmental drivers in aquatic animals. The focus of this study was to determine the main forces that drive mollusc bivalve behavior in situ. To answer this question, the authors continuously studied the valve movements of permanently immersed oysters, Crassostrea gigas, during a 1-year-long in situ study. Valve behavior was monitored with a specially build valvometer, which allows continuously recording of up to 16 bivalves at high frequency (10 Hz). The results highlight a strong relationship between the rhythms of valve behavior and the complex association of the sun-earth-moon orbital positions. Permanently immersed C. gigas follows a robust and s... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798614 Sat, 30 Apr 2011 23:00:00 +0100 4798614 http://www.medworm.com/index.php?rid=4798613&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539423%26dopt%3DAbstract This study evaluates the administration time-of-day effects on propofol pharmacokinetics and sedative response in rabbits. Nine rabbits were sedated with 5 mg/kg propofol at three local clock times: 10:00, 16:00, and 22:00 h. Each rabbit served as its own control by being given a single infusion at the three different times of day on three separate occasions. Ten arterial blood samples were collected during each clock-time experiment for propofol assay. A two-compartment model was used to describe propofol pharmacokinetics, and the pedal withdrawal reflex was used as the sedation pharmacodynamic response. The categorical data comprising the presence or absence of pedal withdrawal reflex was described by a logistic model. The typical volume of the central compartment equaled 7.67 L an... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798613 Sat, 30 Apr 2011 23:00:00 +0100 4798613 http://www.medworm.com/index.php?rid=4798612&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539424%26dopt%3DAbstract Authors: Zornoza-Moreno M, Fuentes-Hernández S, Sánchez-Solis M, Rol MÁ, Larqué E, Madrid AJ The authors developed a method useful for home measurement of temperature, activity, and sleep rhythms in infants under normal-living conditions during their first 6 mos of life. In addition, parametric and nonparametric tests for assessing circadian system maturation in these infants were compared. Anthropometric parameters plus ankle skin temperature and activity were evaluated in 10 infants by means of two data loggers, Termochron iButton (DS1291H, Maxim Integrated Products, Sunnyvale, CA) for temperature and HOBO Pendant G (Hobo Pendant G Acceleration, UA-004-64, Onset Computer Corporation, Bourne, MA) for motor activity, located in special baby socks specifically designed for the study... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798612 Sat, 30 Apr 2011 23:00:00 +0100 4798612 http://www.medworm.com/index.php?rid=4798611&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539425%26dopt%3DAbstract This study is the first to assess QOL in normative, healthy adolescents and to demonstrate strong associations between morning-evening preference and QOL. These findings enhance the need to identify young individuals with an evening preference, and to be aware of the characteristics and manifestations of the evening chronotype on daytime and nighttime behaviors in adolescence. (Author correspondence: Orna@yvc.ac.il ). PMID: 21539425 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798611 Sat, 30 Apr 2011 23:00:00 +0100 4798611 http://www.medworm.com/index.php?rid=4798610&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539426%26dopt%3DAbstract Authors: Armstrong RG, Kenny GP, Green G, Seely AJ As heart-rate variability (HRV) is under evaluation in clinical applications, the authors sought to better define the interdependent impact of age, maximal exercise, and diurnal variation under physiologic conditions. The authors evaluated the diurnal changes in HRV 24-h pre- and post-maximal aerobic exercise testing to exhaustion in young (19-25 yrs, n = 12) and middle-aged (40-55 yrs, n = 12) adults. Subjects wore a portable 5-lead electrocardiogram holter for 48 h (24 h prior to and following a maximal aerobic capacity test). Time-, frequency-, time-frequency-, and scale-invariant-domain measures of HRV were computed from RR-interval data analyzed using a 5-min window size and a 2.5-min step size, resulting in a differen... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798610 Sat, 30 Apr 2011 23:00:00 +0100 4798610 http://www.medworm.com/index.php?rid=4798609&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539427%26dopt%3DAbstract Authors: Kershenbaum A, Kershenbaum A, Tarabeia J, Stein N, Lavi I, Rennert G It has been shown that the population average blood glucose level of diabetes patients shows seasonal variation, with higher levels in the winter than summer. However, seasonality in the population averages could be due to a tendency in the individual to seasonal variation, or alternatively due to occasional high winter readings (spiking), with different individuals showing this increase in different winters. A method was developed to rule out spiking as the dominant pattern underlying the seasonal variation in the population averages. Three years of data from three community-serving laboratories in Israel were retrieved. Diabetes patients (N = 3243) with a blood glucose result every winter and summer ove... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798609 Sat, 30 Apr 2011 23:00:00 +0100 4798609 http://www.medworm.com/index.php?rid=4798608&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539428%26dopt%3DAbstract Authors: Wirtz A, Nachreiner F, Rolfes K Several attributes of the work schedule can increase the risk of occupational injuries and accidents, health impairments, and reduced social participation. Although previous studies mainly focused on the effects of shiftwork and long working hours on employee health and safety, there is little evidence of a potential negative impact of working Sundays on the incidence of occupational accidents, health impairments, and work-life balance. A representative sample of employed workers in 31 member and associated states of the European Union (n = 23,934) served as the database for a cross-sectional analysis. The sample was collected via face-to-face interviews in the year 2005. The association of the risks of occupational accidents, health impairm... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798608 Sat, 30 Apr 2011 23:00:00 +0100 4798608 http://www.medworm.com/index.php?rid=4798607&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539429%26dopt%3DAbstract Authors: Selvi Y, Smolensky MH, Boysan M, Aydin A, Besiroglu L, Atli A, Gumrukcuoglu HA Population-based studies indicate the risk of acute myocardial infarction (AMI) is greatest in the morning, during the initial hours of diurnal activity. The aim of this pilot study was to determine whether chronotype, i.e., morningness and eveningness, impacts AMI onset time. The sample comprised 63 morning- and 40 evening-type patients who were classified by the Horne-Östberg Morningness-Eveningness Questionnaire (MEQ) in the hospital after experiencing the AMI. The average wake-up and bed times of morning types were ∼2 h earlier than evening types. Although the lag in time between waking up from nighttime sleep and AMI onset during the day did not differ between the two chronotypes, the actu... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798607 Sat, 30 Apr 2011 23:00:00 +0100 4798607 http://www.medworm.com/index.php?rid=4798606&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539430%26dopt%3DAbstract Authors: Schernhammer ES, Stone KL PMID: 21539430 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798606 Sat, 30 Apr 2011 23:00:00 +0100 4798606 http://www.medworm.com/index.php?rid=4798605&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21539431%26dopt%3DAbstract Authors: Haim A, Kloog I, Rennert HS, Portnov BA PMID: 21539431 [PubMed - in process] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4798605 Sat, 30 Apr 2011 23:00:00 +0100 4798605 http://www.medworm.com/index.php?rid=4694289&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452914%26dopt%3DAbstract In this study, the authors analyzed the diel expression of per1, clock, and aanat2 in unfertilized rainbow trout oocytes and embryos maintained under either a 12:12-h light:dark (LD) cycle or continuous illumination (LL) from fertilization. 24-h profiles in expression were measured at fertilization as well as 8, 21 42, and 57 days postfertilization (dpf). Both per1 and clock were expressed in unfertilized oocytes and all embryonic stages, whereas aanat2 expression was only measureable from 8 dpf. A reduction in both per1 and clock mean expression levels between unfertilized oocytes/0-1 dpf embryos and 8-9 dpf embryos was suggestive of a transition from maternal RNA to endogenous mRNA expression. Although aanat2 expression was not clearly associated with photic conditions, photoperiod treat... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694289 Thu, 31 Mar 2011 23:00:00 +0100 4694289 http://www.medworm.com/index.php?rid=4694286&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452915%26dopt%3DAbstract Authors: Durgan DJ, Tsai JY, Grenett MH, Pat BM, Ratcliffe WF, Villegas-Montoya C, Garvey ME, Nagendran J, Dyck JR, Bray MS, Gamble KL, Gimble JM, Young ME Circadian dyssynchrony of an organism (at the whole-body level) with its environment, either through light-dark (LD) cycle or genetic manipulation of clock genes, augments various cardiometabolic diseases. The cardiomyocyte circadian clock has recently been shown to influence multiple myocardial processes, ranging from transcriptional regulation and energy metabolism to contractile function. The authors, therefore, reasoned that chronic dyssychrony of the cardiomyocyte circadian clock with its environment would precipitate myocardial maladaptation to a circadian challenge (simulated shiftwork; SSW). To test this hypothesis, 2- and 2... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694286 Thu, 31 Mar 2011 23:00:00 +0100 4694286 http://www.medworm.com/index.php?rid=4694285&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452916%26dopt%3DAbstract Authors: Polidarová L, Sládek M, Soták M, Pácha J, Sumová A Physiological functions of the gastrointestinal tract (GIT) are temporally controlled such that they exhibit circadian rhythms. The circadian rhythms are synchronized with the environmental light-dark cycle via signaling from the central circadian clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus, and by food intake. The aim of the study was to determine the extent to which disturbance in the SCN signaling via prolonged exposure to constant light affects circadian rhythms in the liver, duodenum, and colon, as well as to determine whether and to what extent food intake can restore rhythmicity in individual parts of the GIT. Adult male rats were maintained in constant light (LL) for 30 days and fed ad l... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694285 Thu, 31 Mar 2011 23:00:00 +0100 4694285 http://www.medworm.com/index.php?rid=4694284&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452917%26dopt%3DAbstract Authors: Hariri N, Thibault L The eating pattern is altered by high-fat diet-induced obesity. To clarify whether this is dependent on the fatty acid profile of the diet, the authors conducted two studies on adult female Sprague-Dawley rats fed normal-fat chow or high-fat diets with varying fatty acid composition. Eating pattern and body weight were assessed in rats fed canola-based (low in saturated fatty acids) or lard-based (moderate in saturated fatty acids) diets for 7 days, and in animals fed chow or canola- or butter-based diets (rich in saturated fatty acids) for 43 days. These parameters were also determined when restricted amounts of low-fat canola- or butter-based diets were consumed for 25 days. Early exposure to canola or lard high-fat feeding or prolonged access to canola-... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694284 Thu, 31 Mar 2011 23:00:00 +0100 4694284 http://www.medworm.com/index.php?rid=4694283&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452918%26dopt%3DAbstract This study presents the Circadian Energy Scale (CIRENS), a very short and simple chronotype measurement tool based on energy. The CIRENS consists of two introspective questions about the usual energy level (very low, low, moderate, high, or very high, scored 1 to 5) in the morning and in the evening. The difference between energy level scores (-4 to 4) felt by respondents in the evening and morning defines the chronotype score and classification. A concurrent validity analysis of the CIRENS with the widely used Horne and Östberg Morningness-Eveningness Questionnaire (MEQ) was conducted using a sample of 225 college students, and with MSFsc, a sleep-based chronotype assessment tool based on the Munich Chronotype Questionnaire (MCTQ), using a sample of 34,530 subjects (18-83 yrs, 27% males)... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694283 Thu, 31 Mar 2011 23:00:00 +0100 4694283 http://www.medworm.com/index.php?rid=4694282&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452919%26dopt%3DAbstract Authors: Urbán R, Magyaródi T, Rigó A The impact of diurnal preferences on health-related behaviors is acknowledged but relatively understudied. The aim of this study was threefold: (1) testing the measurement model of the Hungarian version of the reduced Horne-Östberg Morningness-Eveningness Questionnaire (Hungarian Version of the rMEQ); (2) estimating chronotypes and their prevalence; and (3) analyzing the relationship between morningness-eveningness/chronotypes and health-impairing behaviors, including smoking, alcohol use, and physical inactivity in adolescents. Self-reported data on the Hungarian version of the rMEQ, smoking, alcohol use, and physical inactivity obtained from Hungarian high-school students (ninth grade, N = 2565) were analyzed with confirmatory factor anal... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694282 Thu, 31 Mar 2011 23:00:00 +0100 4694282 http://www.medworm.com/index.php?rid=4694281&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452920%26dopt%3DAbstract This study analyzes the influence of circadian typology on several types of drug consumption (habitual or sporadic), hangover symptoms (past 12 mos), and, more specifically, hazardous alcohol consumption of young adults. Five hundred seventeen university students (173 males), between 17 and 30 yrs of age, answered the Composite Scale of Morningness (CSM), the Alcohol Use Disorders Identification Test (AUDIT), and a self-referred questionnaire on drug consumption during the previous month and on the prevalence of different hangover symptoms during the previous year. Our results confirm a higher prevalence of consumption of addictive substances, both legal (nicotine and cola drinks) and illegal (cannabis and ecstasy), in evening- compared to morning- and neither-type subjects (p < .00... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694281 Thu, 31 Mar 2011 23:00:00 +0100 4694281 http://www.medworm.com/index.php?rid=4694280&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452921%26dopt%3DAbstract The objective goal of this study was to examine the association between disrupted RARs and risk of CVD events in older men. A total of 2968 men aged 67 yrs and older wore wrist actigraphs for 115 ± 18 consecutive hours. RAR parameters were computed from wrist actigraphy data and expressed as quartiles (Q). CVD events consisted of a composite outcome of coronary heart disease (CHD), stroke, and peripheral vascular disease (PVD) events. Secondary analyses examined associations between RARs and individual components of the composite outcome (CHD, stroke, and PVD). There were 490 CVD events over an average of 4.0 ± 1.2 yrs. Overall, reduced amplitude (HR = 1.31, 95% confidence interval [CI] 1.01-1.71 for Q2 vs. Q4) and greater minimum (HR = 1.33, 95% CI 1.01-1.73 for Q4 vs. Q... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694280 Thu, 31 Mar 2011 23:00:00 +0100 4694280 http://www.medworm.com/index.php?rid=4694279&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452922%26dopt%3DAbstract Authors: To H, Yoshimatsu H, Tomonari M, Ida H, Tsurumoto T, Tsuji Y, Sonemoto E, Shimasaki N, Koyanagi S, Sasaki H, Ieiri I, Higuchi S, Kawakami A, Ueki Y, Eguchi K Methotrexate (MTX) is the most important drug for treating rheumatoid arthritis (RA). It has been stated that cytokines play an important role in the pathogenesis of RA, and that cytokine levels increase and show 24-h rhythms in RA patients. Previously, we found that arthritis was relieved after the administration of MTX at specific times in synchronization with the 24-h rhythm of tumor necrosis factor (TNF)-α in collagen-induced arthritis (CIA) animals. Based on our findings in an earlier study of the dosing time-dependent effects of MTX in MRL/lpr mice, which develop autoimmune disorders that share similarities with hum... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694279 Thu, 31 Mar 2011 23:00:00 +0100 4694279 http://www.medworm.com/index.php?rid=4694278&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452923%26dopt%3DAbstract Authors: Brousse E, Forget C, Riedel M, Marlot M, Mechkouri M, Smolensky MH, Touitou Y, Reinberg A The aim of the study was to assess the group 24-h pattern of lag time (LT) in response by regular and volunteer firemen (RFM and VFM) to calls for medical help (CFMH), specifically calls for out-of-hospital cardiac arrest (OHCA). LT, duration in min between a CFMH and departure of service vehicle equipped with a semiautomated defibrillator and generally staffed with four well-trained and ready-to-go FM, represents the integrated duration of several processes, each with separate reaction and decision-making times. The exact time of each CFHM (in min, h, day, month, yr) was recorded electronically, and the exact departure time from the station of the responding FM vehicle was recorded by an... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694278 Thu, 31 Mar 2011 23:00:00 +0100 4694278 http://www.medworm.com/index.php?rid=4694277&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452924%26dopt%3DAbstract This study investigates the effect of mild physical activity before bedtime on the sleep pattern and heart rate during the night. Nine healthy subjects underwent a habituation night, a reference night, and a physical induction night. The physical induction night did not alter the sleep pattern. Physical activity before bedtime resulted in higher heart rate variance during slow-wave sleep. The low-frequency/high-frequency component (LF/HF) ratio during slow-wave sleep in the physical induction night was significantly higher than during the reference night. Increased mean heart rate and higher LF/HF ratio are related to decreased parasympathetic dominance. Exercise up to 1 h before bedtime thus seems to modify the quality of sleep. (Author correspondence: Daniel.Berckmans@biw.kuleuven.be )... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694277 Thu, 31 Mar 2011 23:00:00 +0100 4694277 http://www.medworm.com/index.php?rid=4694276&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21452925%26dopt%3DAbstract Authors: PMID: 21452925 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4694276 Thu, 31 Mar 2011 23:00:00 +0100 4694276 http://www.medworm.com/index.php?rid=4395650&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231870%26dopt%3DAbstract Authors: de Lima LH, Dos Santos KP, de Lauro Castrucci AM The avian circadian system is composed of the retina, the mammalian homolog region of the suprachiasmatic nucleus (SNC), and the pineal gland. The retina, itself, displays many rhythmic physiological events, such as movements of photoreceptor cells, opsin expression, retinal reisomerization, and melatonin and dopamine production and secretion. Altogether, these rhythmic events are coordinated to predict environmental changes in light conditions during the day, optimizing retina function. The authors investigated the expression pattern of the melanopsin genes Opn4x and Opn4m, the clock genes Clock and Per2, and the genes for the key enzymes N-Acetyltransferase and Tyrosine Hidroxylase in chicken embryo dispersed retinal cells. Pr... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395650 Tue, 25 Jan 2011 22:03:39 +0100 4395650 http://www.medworm.com/index.php?rid=4395649&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231871%26dopt%3DAbstract Authors: Fonken LK, Morris JS, Nelson RJ Environmental experiences during development provide animals with important information about future conditions. Siberian hamsters are photoperiodic rodents that dramatically adjust their physiology and behavior to adapt to seasonal changes. For example, during short winter-like days, hamsters enhance some components of immune function putatively to cope with increasing environmental challenges. Furthermore, early life stress alters the developmental course of the immune system. Overall, immune function is typically suppressed in response to chronic stress, but responses vary depending on the type of stress and components of immune function assessed. This led us to hypothesize that delayed-type hypersensitivity (DTH), an antigen-specific, cell-m... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395649 Tue, 25 Jan 2011 22:03:10 +0100 4395649 http://www.medworm.com/index.php?rid=4395648&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231872%26dopt%3DAbstract In conclusion, these results revealed that the toxicity and effectiveness of both anesthetic substances is highest during daytime, the active phase of fish, thus suggesting a link between the daily rhythms of behavior and toxicity. (Author correspondence: javisan@um.es ). PMID: 21231872 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395648 Tue, 25 Jan 2011 22:02:44 +0100 4395648 http://www.medworm.com/index.php?rid=4395647&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231873%26dopt%3DAbstract This study explores whether different class times affect students' achievement and examines the performance of students on final exams administered at 09:30 h for differences according to chronotype. A total of 1471 university students between 18 and 25 yrs of age responded to a morningness-eveningness questionnaire (MEQ), and data on their cumulative grade point averages (CGPA) were also collected from their transcripts. Some of the students in the sample attended classes during the first teaching period, which started at 08:00 h and ended at 14:50 h, and the remaining students followed the second schedule, which started at 15:00 h and ended at 21:50 h. MEQ scores were found to differ by sex. MEQ scores partially predicted academic success and that students' academic achievement... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395647 Tue, 25 Jan 2011 22:02:24 +0100 4395647 http://www.medworm.com/index.php?rid=4395646&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231874%26dopt%3DAbstract Authors: Braeckman L, Verpraet R, Van Risseghem M, Pevernagie D, De Bacquer D Sleepiness and sleep complaints are common among professional drivers. Sleepiness is a considerable problem not only because it affects the drivers' well-being, but also because of the consequences for performance and safety. Assessment of the (self-reported) prevalence and research into the risk factors are thus an important health issue and are also indispensable to prevent productivity loss and work-related accidents and injuries. Therefore, the aim of this study was to describe sleeping, driving, and health characteristics of Belgian truck drivers and to determine occupational and individual factors associated with poor sleep quality and daytime sleepiness. Cross-sectional data were collected using a self... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395646 Tue, 25 Jan 2011 22:02:09 +0100 4395646 http://www.medworm.com/index.php?rid=4395645&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231875%26dopt%3DAbstract In conclusion, although there is a marked reduction in MCAv in the morning, there is an absence of diurnal variation in the onset of and associated physiological responses associated with IOH and DOH. These responses, at least in this population, are unlikely contributors to the diurnal variation in orthostatic tolerance. (Author correspondence: N.C.Lewis@2004.ljmu.ac.uk ). PMID: 21231875 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395645 Tue, 25 Jan 2011 22:01:52 +0100 4395645 http://www.medworm.com/index.php?rid=4395644&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231876%26dopt%3DAbstract Authors: Thijssen DH, Eijsvogels TM, Hesse M, Ballak DB, Atkinson G, Hopman MT Individuals with a spinal cord injury (SCI) have compromised afferent and efferent information below the lesion. Intact afferent information regarding skin temperature and the ability to regulate skin blood flow lead to an altered heat balance, which may impact the circadian variation in core body temperature (Tcore) and sleep-wake cycle. The authors assessed the circadian variation of Tcore in SCI individuals and able-bodied controls matched for the timing of the sleep-wake cycle. The authors examined subjects who had a high (cervical) or a low (thoracic) lesion. Intestinal Tcore (telemetry system) and physical activity (ambulatory activity monitor) levels were measured continuously and simultaneously in 8 ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395644 Tue, 25 Jan 2011 22:01:24 +0100 4395644 http://www.medworm.com/index.php?rid=4395643&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231877%26dopt%3DAbstract Authors: Borisenkov MF According to the hypothesis of circadian disruption, external factors that disturb the function of the circadian system can raise the risk of malignant neoplasm and reduce life span. Recent work has shown that the functionality of the circadian system is dependent not only on latitude of residence but also on the region's position in the time zone. The purpose of the present research was to examine the influence of latitude and time zone on cancer incidence, cancer mortality, and life expectancy at birth. A stepwise multiple regression analysis was carried out on residents of 59 regions of the European part of the Russian Federation (EPRF) using age-standardized parameters (per 100,000) of cancer incidence (CI), cancer mortality (CM), and life expectancy at birth... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395643 Tue, 25 Jan 2011 22:01:04 +0100 4395643 http://www.medworm.com/index.php?rid=4395642&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231878%26dopt%3DAbstract Authors: Lone SR, Ilangovan V, Murugan M, Sharma VK We assessed the effect of different day/night lengths on the pre-adult developmental time of two species of Camponotus ants that normally develop in dark underground nests. We assayed larval (egg-to-pupal formation), pupal (pupal formation-to-adult emergence), and pre-adult (egg-to-adult emergence) durations in these ants under three different light/dark (LD) cycles of 12:12 h, 10:14 h, and 14:10 h. We observed that the pre-adult development time of ants under these day lengths was significantly different. Although both species developed fastest under 12:12 h LD, when asymmetric LD cycles were compared, night-active species (Camponotus compressus) developed faster under short days (10:14 h) and day-active species (C. paria) ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395642 Tue, 25 Jan 2011 22:00:53 +0100 4395642 http://www.medworm.com/index.php?rid=4395641&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231879%26dopt%3DAbstract Authors: Selvi Y, Aydin A, Atli A, Boysan M, Selvi F, Besiroglu L Morning- and evening-type individuals differ on a number of psychological and biological variables. There has been increasing interest in the relationship between chronotype and personality traits. The aim of this study was to investigate the relationship between impulsivity and chronotype in suicide attempters. Eighty-nine suicide attempters were included in the study, and systematic information on suicide attempts was recorded. The Morningness-Eveningness Questionnaire was applied to determine chronotype, and attempter impulsivity was measured by the total score of the Barratt Impulsiveness Scale. Significant differences between chronotype and impulsivity scores were found. Evening-type subjects reported significantly ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395641 Tue, 25 Jan 2011 22:00:47 +0100 4395641 http://www.medworm.com/index.php?rid=4395640&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21231880%26dopt%3DAbstract Authors: PMID: 21231880 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4395640 Tue, 25 Jan 2011 22:00:40 +0100 4395640 http://www.medworm.com/index.php?rid=4321546&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182399%26dopt%3DAbstract Authors: Uchikawa M, Kawamura M, Yamauchi N, Hattori MA Circadian rhythms are modulated in a variety of peripheral tissues, including in the uterus where endometrial stromal cells (UESCs) undergo proliferation and differentiation (decidualization) during gestation. Here the authors focused on circadian rhythms in UESCs during implantation and decidualization in rodents. As revealed by analyses of cultured UESCs from pregnant Per2 promoter-dLuc transgenic rats, Per2 oscillation of ∼24 h was observed in response to dexamethasone. Per2 oscillation was enhanced in UESCs during implantation, whereas they were attenuated during decidualization. In vivo studies showed that PER2 protein in the uteri displayed a peak at zeitberger time 4 (ZT 4) (day 4.50 of gestation) and a trough at ZT 12 ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321546 Fri, 07 Jan 2011 23:47:41 +0100 4321546 http://www.medworm.com/index.php?rid=4321545&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182400%26dopt%3DAbstract Authors: Tischkau SA, Howell RE, Hickok JR, Krager SL, Bahr JM The molecular circadian clock mechanism is highly conserved between mammalian and avian species. Avian circadian timing is regulated at multiple oscillatory sites, including the retina, pineal, and hypothalamic suprachiasmatic nucleus (SCN). Based on the authors' previous studies on the rat ovary, it was hypothesized that ovarian clock timing is regulated by the luteinizing hormone (LH) surge. The authors used the chicken as a model to test this hypothesis, because the timing of the endogenous LH surge is accurately predicted from the time of oviposition. Therefore, tissues can be removed before and after the LH surge, allowing one to determine the effect of LH on specific clock genes. The authors first examined the 24-h ex... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321545 Fri, 07 Jan 2011 23:47:37 +0100 4321545 http://www.medworm.com/index.php?rid=4321544&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182401%26dopt%3DAbstract Authors: Peliciari-Garcia RA, Zanquetta MM, Andrade-Silva J, Gomes DA, Barreto-Chaves ML, Cipolla-Neto J Melatonin, the pineal gland hormone, provides entrainment of many circadian rhythms to the ambient light/dark cycle. Recently, cardiovascular studies have demostrated melatonin interactions with many physiological processes and diseases, such as hypertension and cardiopathologies. Although membrane melatonin receptors (MT1, MT2) and the transcriptional factor RORα have been reported to be expressed in the heart, there is no evidence of the cell-type expressing receptors as well as the possible role of melatonin on the expression of the circadian clock of cardiomyocytes, which play an important role in cardiac metabolism and function. Therefore, the aim of this study was to evaluate... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321544 Fri, 07 Jan 2011 23:47:34 +0100 4321544 http://www.medworm.com/index.php?rid=4321543&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182402%26dopt%3DAbstract In conclusion, melatonin and ramelteon showed identical periods of circadian sensitivity at CT10 (advance) and CT2 (delay) to shift the onset of circadian activity rhythms in vivo and the peak of SCN neuronal firing rhythms in vitro. (Author correspondence: mdubo@buffalo.edu). PMID: 21182402 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321543 Fri, 07 Jan 2011 23:47:30 +0100 4321543 http://www.medworm.com/index.php?rid=4321542&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182403%26dopt%3DAbstract Authors: Del Pozo A, Sánchez-Férez JA, Sánchez-Vázquez FJ To investigate daily feeding rhythms in zebrafish, the authors have developed a new self-feeding system with an infrared photocell acting as a food-demand sensor, which lets small-size fish such as zebrafish trigger a self-feeder. In this paper, the authors used eight groups of 20 fish. Locomotor activity rhythms were also investigated by means of infrared sensors. Under a 12 h:12 h light (L)-dark (D) cycle, zebrafish showed a clear nocturnal feeding pattern (88.0% of the total daily food-demands occurring in the dark phase), concentrated during the last 4 h of the dark phase. In contrast, locomotor activity was mostly diurnal (88.2% of total daily activity occurring in the light phase). Moreover, both feeding and loco... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321542 Fri, 07 Jan 2011 23:47:26 +0100 4321542 http://www.medworm.com/index.php?rid=4321541&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182404%26dopt%3DAbstract In conclusion, individual endogenous rhythms predict social integration. (Author correspondence: sophie.lumineau@univ-rennes1.fr). PMID: 21182404 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321541 Fri, 07 Jan 2011 23:47:22 +0100 4321541 http://www.medworm.com/index.php?rid=4321540&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182405%26dopt%3DAbstract Authors: Schöttner K, Limbach A, Weinert D Djungarian hamsters bred at the authors' institute reveal two distinct circadian phenotypes, the wild-type (WT) and DAO type. The latter is characterized by a delayed activity-onset, probably due to a deficient mechanism for photic entrainment. Experiments with zeitgeber shifts have been performed to gain further insight into the mechanisms underlying this phenomenon. Advancing and delaying phase shifts were produced by a single lengthening or shortening of the dark (D) or light (L) time by 6 h. Motor activity was recorded by passive infrared motion detectors. All WT hamsters re-entrained following various zeitgeber shifts and nearly always in the same direction as the zeitgeber shift. On the other hand, a considerable proportion of the DAO... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321540 Fri, 07 Jan 2011 23:47:18 +0100 4321540 http://www.medworm.com/index.php?rid=4321539&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182406%26dopt%3DAbstract Authors: Rotics S, Dayan T, Levy O, Kronfeld-Schor N Light masking has been studied almost exclusively in the laboratory. The authors populated four field enclosures with locally coexisting nocturnal Acomys cahirinus and diurnal A. russatus, and monitored their body temperatures (T(b)) using implanted temperature-sensitive radio transmitters. A 3-h light pulse was initiated at the beginning of two consecutive nights; preceding nights were controls. A. cahirinus T(b) and calculated activity levels decreased significantly during the light pulse, demonstrating a negative light masking response (light effect on T(b): -0.32°C ± 0.15°C; average calculated activity records during the light pulse: 7 ± 1.53, control: 9.8 ± 1.62). Diurnal A. russatus did not respond to the light... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321539 Fri, 07 Jan 2011 23:47:15 +0100 4321539 http://www.medworm.com/index.php?rid=4321538&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182407%26dopt%3DAbstract Authors: Kloog I, Portnov BA, Rennert HS, Haim A Due to its disruptive effects on circadian rhythms and sleep deprivation at night, shiftworking is currently recognized as a risk factor for breast cancer (BC). As revealed by the present analysis based on a comparative case-control study of 1679 women, exposure to light-at-night (LAN) in the "sleeping habitat" is significantly associated with BC risk (odds ratio [OR] = 1.220, 95% confidence interval [CI] = 1.118-1.311; p < .001), controlling for education, ethnicity, fertility, and alcohol consumption. The novelty of the present research is that, to the best of the authors' knowledge, it is the first study to have identified an unequivocal positive association between bedroom-light intensity and BC risk. Thus, according t... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321538 Fri, 07 Jan 2011 23:47:11 +0100 4321538 http://www.medworm.com/index.php?rid=4321537&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21182408%26dopt%3DAbstract Authors: Di Milia L, Folkard S, Hill J, Walker C The Circadian Amplitude and Phase Scale (CAPS) is a new self-report tool that aims to assess amplitude and phase. The CAPS consists of three factors made up of 38 items. Amplitude is posited to be assessed via two of these factors: time awareness (TA) and/or strength of preference (SOP). The remaining factor, phase, is assessed via the existing Preferences Scale (PS). Given there is no published research using this measure, the authors undertook two studies to examine its psychometric properties and construct validity. In a sample of 351 North American students, the authors identified a three-factor 34-item model using principal components analysis. The components explained 39% of the variance, and scale reliability ranged from 0.73 (SOP... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4321537 Fri, 07 Jan 2011 23:47:07 +0100 4321537 http://www.medworm.com/index.php?rid=4107302&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969517%26dopt%3DAbstract CIRCADIAN PROFILES IN THE EMBRYONIC CHICK HEART: L-TYPE VOLTAGE-GATED CALCIUM CHANNELS AND SIGNALING PATHWAYS. Chronobiol Int. 2010 Oct.;27(9-10):1673-1696 Authors: Ko ML, Shi L, Grushin K, Nigussie F, Ko GY Circadian clocks exist in the heart tissue and modulate multiple physiological events, from cardiac metabolism to contractile function and expression of circadian oscillator and metabolic-related genes. Ample evidence has demonstrated that there are endogenous circadian oscillators in adult mammalian cardiomyocytes. However, mammalian embryos cannot be entrained independently to light-dark (LD) cycles in vivo without any maternal influence, but circadian genes are well expressed and able to oscillate in embryonic stages. The authors took advantage of using chick embryos tha... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107302 Thu, 30 Sep 2010 23:00:00 +0100 4107302 http://www.medworm.com/index.php?rid=4107301&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969518%26dopt%3DAbstract DIURNAL EXPRESSION OF CLOCK GENES IN PINEAL GLAND AND BRAIN AND PLASMA LEVELS OF MELATONIN AND CORTISOL IN ATLANTIC SALMON PARR AND SMOLTS. Chronobiol Int. 2010 Oct.;27(9-10):1697-1714 Authors: Huang TS, Ruoff P, Fjelldal PG In Atlantic salmon, the preadaptation to a marine life, i.e., parr-smolt transformation, and melatonin production in the pineal gland are regulated by the photoperiod. However, the clock genes have never been studied in the pineal gland of this species. The aim of the present study was to describe the diurnal expression of clock genes (Per1-like, Cry2, and Clock) in the pineal gland and brain of Atlantic salmon parr and smolts in freshwater, as well as plasma levels of melatonin and cortisol. By employing an out-of-season smolt production model, the parr-sm... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107301 Thu, 30 Sep 2010 23:00:00 +0100 4107301 http://www.medworm.com/index.php?rid=4107300&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969519%26dopt%3DAbstract EFFECT OF CONTINUOUS LIGHT ON DAILY LEVELS OF PLASMA MELATONIN AND CORTISOL AND EXPRESSION OF CLOCK GENES IN PINEAL GLAND, BRAIN, AND LIVER IN ATLANTIC SALMON POSTSMOLTS. Chronobiol Int. 2010 Oct.;27(9-10):1715-1734 Authors: Huang TS, Ruoff P, Fjelldal PG Continuous light is a common practice in salmon farming, where it is used to enhance growth, induce smoltification, and regulate puberty. However, knowledge about how different tissues receive information about daylength is limited. The aim of the present study was to evaluate the daily expression of clock (Per1-like, Cry2, and Clock), the nuclear transcription factor (peroxisome proliferator-activated receptor, PPAR; CCAAT/enhancer binding protein, C/EBP), and the endoplasmic reticulum (ER) stress (protein disulfide isomerase... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107300 Thu, 30 Sep 2010 23:00:00 +0100 4107300 http://www.medworm.com/index.php?rid=4107299&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969520%26dopt%3DAbstract PROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-α MEDIATES HIGH-FAT, DIET-ENHANCED DAILY OSCILLATION OF PLASMINOGEN ACTIVATOR INHIBITOR-1 ACTIVITY IN MICE. Chronobiol Int. 2010 Oct.;27(9-10):1735-1753 Authors: Hayashida S, Kuramoto Y, Koyanagi S, Oishi K, Fujiki J, Matsunaga N, Ikeda E, Ohdo S, Shimeno H, Soeda S Acute thrombotic events frequently occur in the early morning among hyperlipidemic patients. The activity of plasminogen activator inhibitor-1 (PAI-1), a potent inhibitor of the fibrinolytic system, oscillates daily, and this is considered one mechanism that underlies the morning onset of acute thrombotic events in hyperlipidemia. Although several studies have reported the expression of the PAI-1 gene is under the control of the circadian clock system, the molecular mechani... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107299 Thu, 30 Sep 2010 23:00:00 +0100 4107299 http://www.medworm.com/index.php?rid=4107298&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969521%26dopt%3DAbstract Authors: Detanico BC, de Souza A, Medeiros LF, Rozisky JR, Caumo W, Hidalgo MP, Battastini AM, Torres IL Circadian rhythms represent an important mechanism to prepare the organism for environmental variations. ATP, ADP, AMP, and adenosine can act as extracellular messengers in a range of biological processes and are metabolized by a number of enzymes, including NTPDases and 5'-nucleotidase. In the present study the authors report that ATPase and ADPase activities present 24-h temporal variations that peak during dark (activity) span. These findings suggest that this enzymatic temporal pattern in blood serum might be important for the normal physiology and function of the organism through the maintenance of extracellular nucleotides at physiological levels. (Author correspondence: iraci... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107298 Thu, 30 Sep 2010 23:00:00 +0100 4107298 http://www.medworm.com/index.php?rid=4107297&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969522%26dopt%3DAbstract PREDICTING HUMAN NOCTURNAL NONVISUAL RESPONSES TO MONOCHROMATIC AND POLYCHROMATIC LIGHT WITH A MELANOPSIN PHOTOSENSITIVITY FUNCTION. Chronobiol Int. 2010 Oct.;27(9-10):1762-1777 Authors: Revell VL, Barrett DC, Schlangen LJ, Skene DJ The short-wavelength (blue) light sensitivity of human circadian, neurobehavioral, neuroendocrine, and neurophysiological responses is attributed to melanopsin. Whether melanopsin is the sole factor in determining the efficacy of a polychromatic light source in driving nonvisual responses, however, remains to be established. Monochromatic (λ(max) 437, 479, and 532 nm administered singly and in combination with 479 nm light) and polychromatic (color temperature: 4000 K and 17000 K) light stimuli were photon matched for their predicted ability to... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107297 Thu, 30 Sep 2010 23:00:00 +0100 4107297 http://www.medworm.com/index.php?rid=4107296&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969523%26dopt%3DAbstract PHASE RELATIONSHIP BETWEEN SKIN TEMPERATURE AND SLEEP-WAKE RHYTHMS IN WOMEN WITH VASCULAR DYSREGULATION AND CONTROLS UNDER REAL-LIFE CONDITIONS. Chronobiol Int. 2010 Oct.;27(9-10):1778-1796 Authors: Gompper B, Bromundt V, Orgül S, Flammer J, Kräuchi K The aim of the study was to investigate whether women with primary vascular dysregulation (VD; main symptoms of thermal discomfort with cold extremities) and difficulties initiating sleep (DIS) exhibit a disturbed phase of entrainment (Ψ) under everyday life conditions. The authors predicted a phase delay of the distal-proximal skin temperature gradient and salivary melatonin rhythms with respect to the sleep-wake cycle in women with VD and DIS (WVD) compared to controls (CON), similar to that found in their previous constant-r... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107296 Thu, 30 Sep 2010 23:00:00 +0100 4107296 http://www.medworm.com/index.php?rid=4107295&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969524%26dopt%3DAbstract The objective of this study is to investigate associations in Japanese adult subjects between evening preference and incidence of depressive states, adjusting for various sleep parameters related to depressive states. The Morningness-Eveningness Questionnaire (MEQ), the Pittsburgh Sleep Quality Index (PSQI), and the Center for Epidemiologic Studies Depression Scale (CES-D) were administered to 1170 individuals (493 males/677 females; mean and range 38.5 and 20-59 yrs) to assess their diurnal preferences, sleeping states, and presence of depression symptoms. Subjects were classified into five chronotypes based on MEQ scores. Evening preference was associated with delayed sleep timing, shortened sleep duration, deteriorated subjective sleep quality, and worsened daytime sleepiness. Logistic ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107295 Thu, 30 Sep 2010 23:00:00 +0100 4107295 http://www.medworm.com/index.php?rid=4107294&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969525%26dopt%3DAbstract ASSOCIATIONS BETWEEN CHRONOTYPE, SLEEP QUALITY, SUICIDALITY, AND DEPRESSIVE SYMPTOMS IN PATIENTS WITH MAJOR DEPRESSION AND HEALTHY CONTROLS. Chronobiol Int. 2010 Oct.;27(9-10):1813-1828 Authors: Selvi Y, Aydin A, Boysan M, Atli A, Agargun MY, Besiroglu L Research interest concerning associations between sleep characteristics and suicidality in psychopathology has been growing. However, possible linkages of suicidality to sleep characteristics in terms of sleep quality and chronotypes among depressive patients have not been well documented. In the current study, the authors investigated the possible effects of sleep quality and chronotype on the severity of depressive symptoms and suicide risk in patients with depressive disorder and healthy controls. The study was conducted on ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107294 Thu, 30 Sep 2010 23:00:00 +0100 4107294 http://www.medworm.com/index.php?rid=4107293&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969526%26dopt%3DAbstract MORNINGNESS PROPENSITY IN YOUNG ADULTS BORN PREMATURELY: THE HELSINKI STUDY OF VERY LOW BIRTH WEIGHT ADULTS. Chronobiol Int. 2010 Oct.;27(9-10):1829-1842 Authors: Strang-Karlsson S, Kajantie E, Pesonen AK, Räikkönen K, Hovi P, Lahti J, Heinonen K, Järvenpää AL, Eriksson JG, Andersson S, Paavonen EJ The authors explored morningness-eveningness propensity in adults born prematurely at very low birth weight (VLBW;  < 1500g) and in controls born at term. At age 21 to 29 yrs, 184 participants completed the Morningness-Eveningness Questionnaire (MEQ). Compared with controls, VLBW adults scored higher in morningness propensity (group difference: 2.8 scores, 95% confidence interval: 0.1 to 5.5; p = .042). This finding was confined to those VLBW adults whose birth weight... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107293 Thu, 30 Sep 2010 23:00:00 +0100 4107293 http://www.medworm.com/index.php?rid=4107292&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969527%26dopt%3DAbstract CHRONOPHARMACOLOGY OF ROFLUMILAST: A COMPARATIVE PHARMACOKINETIC STUDY OF MORNING VERSUS EVENING ADMINISTRATION IN HEALTHY ADULTS. Chronobiol Int. 2010 Oct.;27(9-10):1843-1853 Authors: Bethke TD, Huennemeyer A, Lahu G, Lemmer B The human circadian system is known to affect the pharmacokinetics and pharmacodynamics of several classes of respiratory disease medications. The current study involving 16 healthy adults investigated if the time-of-day of dosing of roflumilast, a novel phosphodiesterase-4 inhibitor, affects its pharmacokinetics. The rate of drug absorption (t(max): 1.50 versus 2.00 h) and peak concentration at t(max) (C(max): 3.79 versus 3.06 µg/L) was slightly greater with morning than evening administration, but without clinical significance. The extent of drug ab... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107292 Thu, 30 Sep 2010 23:00:00 +0100 4107292 http://www.medworm.com/index.php?rid=4107291&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969528%26dopt%3DAbstract SEASONAL VARIATION OF NEONATAL TRANSIENT HYPERTHYROTROPINEMIA IN TEHRAN PROVINCE, 1998-2005. Chronobiol Int. 2010 Oct.;27(9-10):1854-1869 Authors: Ordookhani A, Padyab M, Goldasteh A, Mirmiran P, Richter J, Azizi F Seasonal aggregation and the monthly rate of neonatal transient hyperthyrotropinemia (THT) were assessed. From November 1998 to April 2005, neonates of gestational age ≥37 wks, birth weight 2500-4000 g, birth length 45-55 cm, and 1st min Apgar score >3, who had thyrotropin (TSH) ≥20 mU/L in their cord dried-blood specimen, but without congenital hypothyroidism, were enrolled in the study. The recall rate equals the rate of THT occurrence in this study. Of 47,945 neonates, 555 had THT (recall rate: 1.2%). The aggregated seasonal recall rate (recall for furt... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107291 Thu, 30 Sep 2010 23:00:00 +0100 4107291 http://www.medworm.com/index.php?rid=4107290&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969529%26dopt%3DAbstract This study examined: (1) whether cognitive performance in school-aged children is affected by time-of-day; (2) which functional domains are particularly vulnerable to time-of-day effects; and (3) whether the effects are more pronounced for cognitively more demanding tasks or task conditions. Children, aged 10-12 yrs, were randomly assigned to a test session starting either at 08:30 (n = 802), 10:00 (n = 713), or 13:00 h (n = 652). Speed and accuracy of information processing were evaluated by tasks that assess input-related cognitive processes (e.g., stimulus encoding), central cognitive processes (e.g., working memory, sustained attention), and output-related processes (e.g., response organization) using the Amsterdam Neuropsychological Tasks program. Time-of-day effects in ... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107290 Thu, 30 Sep 2010 23:00:00 +0100 4107290 http://www.medworm.com/index.php?rid=4107289&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969530%26dopt%3DAbstract ESTIMATION OF THE BENCHMARK DURATION OF SHIFTWORK ASSOCIATED WITH WEIGHT GAIN IN MALE JAPANESE WORKERS. Chronobiol Int. 2010 Oct.;27(9-10):1895-1910 Authors: Tanaka K, Sakata K, Oishi M, Morimoto H, Nakada S, Uetani M, Nogawa K, Suwazono Y The authors estimated the benchmark durations (BMDs) and their 95% lower confidence limit (BMDL) for the reference duration of shiftwork for weight gain. A 14-yr prospective cohort study was conducted in male workers at a Japanese steel company (n = 7254) who had received annual health check-ups between 1991 and 2005. The endpoints in the study were either a 5%, 7.5%, or 10% increase in body mass index (BMI) during the period of observation, compared to the BMI at entry. The association between the duration of shiftwork and weight gain wa... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107289 Thu, 30 Sep 2010 23:00:00 +0100 4107289 http://www.medworm.com/index.php?rid=4107288&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969531%26dopt%3DAbstract This article updates the ethical standards and methods for the conduct of high-quality animal and human biological rhythm research, which should be especially useful for new investigators of the rhythms of life. The editors of Chronobiology International adhere to and endorse the Code of Conduct and Best Practice Guidelines of the Committee On Publication Ethics (COPE), which encourages communication of such updates at regular intervals in the journal. The journal accepts papers representing original work, no part of which was previously submitted for publication elsewhere, except as brief abstracts, as well as in-depth reviews. The majority of research papers published in Chronobiology International entails animal and human investigations. The editors and readers of the journal expect aut... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107288 Thu, 30 Sep 2010 23:00:00 +0100 4107288 http://www.medworm.com/index.php?rid=4107287&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969532%26dopt%3DAbstract HABITUAL MODERATE ALCOHOL CONSUMPTION DESYNCHRONIZES CIRCADIAN PHYSIOLOGIC RHYTHMS AND AFFECTS REACTION-TIME PERFORMANCE. Chronobiol Int. 2010 Oct.;27(9-10):1930-1942 Authors: Reinberg A, Touitou Y, Lewy H, Mechkouri M The authors studied longitudinally four healthy young adults to explore if habitual evening intake of a "moderate" amount of wine alters parameters, including period (τ) of circadian rhythms. Subjects, synchronized by diurnal activity from 07.30 h ± 60 min to 23.00 h ± 90 min and nocturnal rest, were studied during a continuous 22-day span: 11 days without alcohol (control) and 11 days with a glass (200 mL) of wine nightly at supper (alcohol). The amount of alcohol ingested with dinner ranged from 0.28 to 0.42 g/kg/24 h/participant and th... Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107287 Thu, 30 Sep 2010 23:00:00 +0100 4107287 http://www.medworm.com/index.php?rid=4107286&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969533%26dopt%3DAbstract Authors: West DW, Burd NA, Phillips SM PMID: 20969533 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107286 Thu, 30 Sep 2010 23:00:00 +0100 4107286 http://www.medworm.com/index.php?rid=4107285&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969534%26dopt%3DAbstract AUTHORS' REPLY. Chronobiol Int. 2010 Oct.;27(9-10):1945-1946 Authors: Hayes LD, Bickerstaff GF, Baker JS PMID: 20969534 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107285 Thu, 30 Sep 2010 23:00:00 +0100 4107285 http://www.medworm.com/index.php?rid=4107284&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20969535%26dopt%3DAbstract Authors: PMID: 20969535 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=4107284 Thu, 30 Sep 2010 23:00:00 +0100 4107284 http://www.medworm.com/index.php?rid=3998429&cid=s_31970_62_f&fid=31970&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20854132%26dopt%3DAbstract This study, in the genetically accessible zebrafish model, lays the foundation for further research regarding the involvement and specific roles of PAR and E4BP4 transcription factors in the vertebrate circadian clock mechanism. (Author correspondence: yoavg@tauex.tau.ac.il ). PMID: 20854132 [PubMed - as supplied by publisher] (Source: Chronobiology International) Chronobiology International journals http://www.medworm.com/rss/comments.php?id=3998429 Tue, 31 Aug 2010 23:00:00 +0100 3998429