MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Circulation' source. Wed, 08 Feb 2012 09:32:33 +0100 http://www.medworm.com/index.php?rid=5661093&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22302838%26dopt%3DAbstract CONCLUSIONS: The endothelium plays important roles in obesity- and age-related disorders through intracellular NF-κB signaling, thereby, ultimately, impacting lifespan. Endothelial NF-κB signaling is a potential target for treating the metabolic syndrome as well as for anti-aging strategies. PMID: 22302838 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661093 Wed, 01 Feb 2012 05:00:00 +0100 5661093 http://www.medworm.com/index.php?rid=5661089&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22302839%26dopt%3DAbstract Authors: Kim JK Abstract Insulin resistance is a major characteristic of type 2 diabetes and develops in multiple organs including skeletal muscle, liver, adipose tissue, and heart(1). Insulin resistance is caused by obesity and therefore establishes an important causal relationship between obesity and type 2 diabetes(2). Insulin resistance also develops in aging, but this process is less well understood. Obesity is a complex physiological state with alterations in lipid metabolism, dysregulated production of hormones, ectopic accumulation of fat, mitochondrial dysfunction, and chronic low-grade inflammation(3,4). All of these abnormalities may independently cause insulin resistance and affect glucose homeostasis, which make insulin resistance as equally complex as obesity itself. ... Circulation journals http://www.medworm.com/rss/comments.php?id=5661089 Wed, 01 Feb 2012 05:00:00 +0100 5661089 http://www.medworm.com/index.php?rid=5661088&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22302840%26dopt%3DAbstract CONCLUSIONS: Current treatment with EES is associated with lower risk of VLST compared with early generation DES. PMID: 22302840 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661088 Wed, 01 Feb 2012 05:00:00 +0100 5661088 http://www.medworm.com/index.php?rid=5661087&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22302841%26dopt%3DAbstract Authors: Cutlip DE Abstract Drug-eluting stents (DES) were introduced to the coronary artery disease treatment market in 2003 with much exuberance and fanfare. With over 70% reduction in restenosis and no apparent safety concerns in one year reports from large randomized clinical trials,(1,2) the opportunity for expansion of the technology seemed limitless. Interventional cardiologists responded with confidence and quickly expanded use to a wide array of "off-label" indications, limited only by initial inventory constraints.(3,4) Some even considered DES as a potential therapy for vulnerable lesions or regions that were not yet hemodynamically significant, and there were concerns by hospitals and others that widespread use of these devices for treatment of traditional surgical dise... Circulation journals http://www.medworm.com/rss/comments.php?id=5661087 Wed, 01 Feb 2012 05:00:00 +0100 5661087 http://www.medworm.com/index.php?rid=5661131&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294621%26dopt%3DAbstract CONCLUSIONS: Inactivation of Rheb protects CMs during ED through activation of autophagy. Rheb and mTORC1 may represent therapeutic targets to reduce myocardial damage during ischemia, particularly in obese patients. PMID: 22294621 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661131 Tue, 31 Jan 2012 05:00:00 +0100 5661131 http://www.medworm.com/index.php?rid=5661130&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294706%26dopt%3DAbstract Authors: Frey P, Connors A, Resnic FS PMID: 22294706 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661130 Tue, 31 Jan 2012 05:00:00 +0100 5661130 http://www.medworm.com/index.php?rid=5661129&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294707%26dopt%3DAbstract Authors: Deo R, Albert CM PMID: 22294707 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661129 Tue, 31 Jan 2012 05:00:00 +0100 5661129 http://www.medworm.com/index.php?rid=5661128&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294708%26dopt%3DAbstract Authors: Loscalzo J PMID: 22294708 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661128 Tue, 31 Jan 2012 05:00:00 +0100 5661128 http://www.medworm.com/index.php?rid=5661127&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294709%26dopt%3DAbstract Authors: Strapazzon G, Beikircher W, Procter E, Brugger H PMID: 22294709 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661127 Tue, 31 Jan 2012 05:00:00 +0100 5661127 http://www.medworm.com/index.php?rid=5661115&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294710%26dopt%3DAbstract Authors: Narayan GS, Sivasubramonian S PMID: 22294710 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661115 Tue, 31 Jan 2012 05:00:00 +0100 5661115 http://www.medworm.com/index.php?rid=5661100&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294711%26dopt%3DAbstract Authors: Abstract The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read manuscripts published on the topic of biomarkers in 2010 and 2011. PMID: 22294711 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661100 Tue, 31 Jan 2012 05:00:00 +0100 5661100 http://www.medworm.com/index.php?rid=5661099&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294712%26dopt%3DAbstract Letter by lecoultre and tam regarding article, "increased adipose tissue oxygen tension in obese compared with lean men is accompanied by insulin resistance, impaired adipose tissue capillarization, and inflammation". Circulation. 2012 Jan 31;125(4):e315 Authors: Lecoultre V, Tam CS PMID: 22294712 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661099 Tue, 31 Jan 2012 05:00:00 +0100 5661099 http://www.medworm.com/index.php?rid=5661098&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294713%26dopt%3DAbstract Letter by karam and marijon regarding article, "atrial fibrillation: outpatient presentation and management". Circulation. 2012 Jan 31;125(4):e317 Authors: Karam N, Marijon E PMID: 22294713 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661098 Tue, 31 Jan 2012 05:00:00 +0100 5661098 http://www.medworm.com/index.php?rid=5661095&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294714%26dopt%3DAbstract Letter by montone et Al regarding article, "atrial fibrillation: outpatient presentation and management". Circulation. 2012 Jan 31;125(4):e318 Authors: Montone RA, Mollo R, Nerla R PMID: 22294714 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661095 Tue, 31 Jan 2012 05:00:00 +0100 5661095 http://www.medworm.com/index.php?rid=5661094&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22294715%26dopt%3DAbstract Letter by Madias Regarding the Article, "Repolarization Alternans Reveals Vulnerability to Human Atrial fibrillation". Circulation. 2012 Jan 31;125(4):e320 Authors: Madias JE PMID: 22294715 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661094 Tue, 31 Jan 2012 05:00:00 +0100 5661094 http://www.medworm.com/index.php?rid=5661135&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22291125%26dopt%3DAbstract Authors: Appel LJ Abstract Recently, the American Heart Association (AHA) adopted a new and ambitious strategic goal - "by 2020, to improve the cardiovascular health of all Americans by 20% while reducing deaths from cardiovascular disease by 20%"(1). In the process, it defined a new concept, cardiovascular health, which is comprised of 7 components: 4 ideal health behaviors (nonsmoking, body mass index < 25 kg/m(2), physical activity at goal levels, and a diet consistent with current recommendations) together with 3 ideal health factors (untreated total cholesterol < 200mg/dL, untreated blood pressure <120/<80 mm Hg, and fasting blood glucose<100 mg/dL). This new approach emphasizes prevention with a focus on achieving and sustaining desirable behaviors. At the time... Circulation journals http://www.medworm.com/rss/comments.php?id=5661135 Mon, 30 Jan 2012 05:00:00 +0100 5661135 http://www.medworm.com/index.php?rid=5661134&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22291126%26dopt%3DAbstract CONCLUSIONS: The number of ideal cardiovascular health metrics is a strong predictor of mortality from all-causes and diseases of the circulatory system. PMID: 22291126 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661134 Mon, 30 Jan 2012 05:00:00 +0100 5661134 http://www.medworm.com/index.php?rid=5661133&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22291127%26dopt%3DAbstract CONCLUSIONS: Maintaining a healthy lifestyle throughout young adulthood is strongly associated with low CVD risk profile in middle age. Public health and individual efforts are needed to improve adoption and maintenance of healthy lifestyles in young adults. PMID: 22291127 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661133 Mon, 30 Jan 2012 05:00:00 +0100 5661133 http://www.medworm.com/index.php?rid=5661132&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22291128%26dopt%3DAbstract Authors: Arena R, Williams M, Forman DE, Cahalin LP, Coke L, Myers J, Hamm L, Kris-Etherton P, Humphrey R, Bittner V, Lavie CJ, PMID: 22291128 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661132 Mon, 30 Jan 2012 05:00:00 +0100 5661132 http://www.medworm.com/index.php?rid=5661136&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22287589%26dopt%3DAbstract CONCLUSIONS: In the GWTG-HF quality improvement program, a significant increase in ICD therapy use was observed over time in all sex and race groups. The previously described racial disparities in ICD use were no longer present by the end of the study period; however, sex differences persisted. PMID: 22287589 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5661136 Fri, 27 Jan 2012 05:00:00 +0100 5661136 http://www.medworm.com/index.php?rid=5643065&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22282327%26dopt%3DAbstract CONCLUSIONS: PCI can be performed in patients with severe symptomatic AS and CAD without an increased risk of short term mortality compared to propensity matched patients without AS. Patients with EF ≤30% and STS score ≥10% are at a highest risk of 30-day mortality after PCI. This finding has significant implications in the management of severe CAD in high risk severe symptomatic AS patients being considered for TAVR. PMID: 22282327 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643065 Thu, 26 Jan 2012 05:00:00 +0100 5643065 http://www.medworm.com/index.php?rid=5643064&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22282328%26dopt%3DAbstract Authors: Kodali SK, Moses JW Abstract Significant coronary artery disease (CAD) is present in up to 50% of patients with symptomatic aortic stenosis (AS). The standard treatment has been coronary artery bypass grafting at the time of surgical aortic valve replacement (AVR). While numerous databases have shown that the addition of bypass grafting to an AVR nearly doubles the mortality, surgical series have shown that leaving significant coronary stenosis untreated increases AVR mortality(1-4). Thus the standard of care for this population has been concomitant coronary artery bypass grafting along with surgical aortic valve replacement. (SELECT FULL TEXT TO CONTINUE). PMID: 22282328 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643064 Thu, 26 Jan 2012 05:00:00 +0100 5643064 http://www.medworm.com/index.php?rid=5643063&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22282329%26dopt%3DAbstract CONCLUSIONS: In older adults, higher circulating total long-chain n-3 PUFA and DHA levels were associated with lower risk of incident AF. These results highlight the need to evaluate whether increased dietary intake of these fatty acids could be effective for primary prevention of AF. PMID: 22282329 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643063 Thu, 26 Jan 2012 05:00:00 +0100 5643063 http://www.medworm.com/index.php?rid=5643080&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271847%26dopt%3DAbstract Authors: Merchant FM, Armoundas AA PMID: 22271847 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643080 Tue, 24 Jan 2012 05:00:00 +0100 5643080 http://www.medworm.com/index.php?rid=5643079&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271848%26dopt%3DAbstract Authors: Barbash IM, Waksman R PMID: 22271848 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643079 Tue, 24 Jan 2012 05:00:00 +0100 5643079 http://www.medworm.com/index.php?rid=5643078&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271849%26dopt%3DAbstract Authors: Furukawa K, Ikeda S, Okamura N, Tashiro M, Tomita N, Furumoto S, Iwata R, Yanai K, Kudo Y, Arai H PMID: 22271849 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643078 Tue, 24 Jan 2012 05:00:00 +0100 5643078 http://www.medworm.com/index.php?rid=5643077&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271850%26dopt%3DAbstract Authors: Blankstein R PMID: 22271850 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643077 Tue, 24 Jan 2012 05:00:00 +0100 5643077 http://www.medworm.com/index.php?rid=5643076&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271851%26dopt%3DAbstract Authors: Atashband A, Ramasubbu K PMID: 22271851 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643076 Tue, 24 Jan 2012 05:00:00 +0100 5643076 http://www.medworm.com/index.php?rid=5643075&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271852%26dopt%3DAbstract Authors: Abstract The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read of those performed in an animal model. PMID: 22271852 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643075 Tue, 24 Jan 2012 05:00:00 +0100 5643075 http://www.medworm.com/index.php?rid=5643074&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271853%26dopt%3DAbstract Letter by cornet et Al regarding article, "relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest". Circulation. 2012 Jan 24;125(3):e287 Authors: Cornet AD, Peters MJ, Kooter AJ PMID: 22271853 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643074 Tue, 24 Jan 2012 05:00:00 +0100 5643074 http://www.medworm.com/index.php?rid=5643073&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271854%26dopt%3DAbstract Letter by bellomo et Al regarding article, "relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest". Circulation. 2012 Jan 24;125(3):e288 Authors: Bellomo R, Bailey M, Nichol A PMID: 22271854 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643073 Tue, 24 Jan 2012 05:00:00 +0100 5643073 http://www.medworm.com/index.php?rid=5643072&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271855%26dopt%3DAbstract Reply to letters regarding article, "relationship between supranormal oxygen tension and outcome after resuscitation from cardiac arrest". Circulation. 2012 Jan 24;125(3):e289 Authors: Kilgannon JH, Trzeciak S, Parrillo JE, Dellinger RP, Milcarek B, Hunter K, Jones AE, Shapiro NI PMID: 22271855 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643072 Tue, 24 Jan 2012 05:00:00 +0100 5643072 http://www.medworm.com/index.php?rid=5643071&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271856%26dopt%3DAbstract Letter by Govindarajan and Salgado Regarding Article, "Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation: An Analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) Trial". Circulation. 2012 Jan 24;125(3):e290 Authors: Govindarajan R, Salgado E PMID: 22271856 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643071 Tue, 24 Jan 2012 05:00:00 +0100 5643071 http://www.medworm.com/index.php?rid=5643070&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271857%26dopt%3DAbstract Letter by Reynolds et al Regarding Article, "Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation: An Analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) Trial". Circulation. 2012 Jan 24;125(3):e291 Authors: Reynolds S, Parra D, Rosenstein RS PMID: 22271857 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643070 Tue, 24 Jan 2012 05:00:00 +0100 5643070 http://www.medworm.com/index.php?rid=5643069&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271858%26dopt%3DAbstract Letter by Reiffel Regarding Article, "Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation: An Analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) Trial". Circulation. 2012 Jan 24;125(3):e292 Authors: Reiffel JA PMID: 22271858 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643069 Tue, 24 Jan 2012 05:00:00 +0100 5643069 http://www.medworm.com/index.php?rid=5643068&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271859%26dopt%3DAbstract Reply to Letters Regarding Article, "Risk of Bleeding With 2 Doses of Dabigatran Compared With Warfarin in Older and Younger Patients With Atrial Fibrillation: An Analysis of the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) Trial". Circulation. 2012 Jan 24;125(3):e293-4 Authors: Eikelboom JW, Connolly SJ, Healey JS, Yang S, Yusuf S, Wallentin L, Oldgren J, Ezekowitz M, Alings M, Kaatz S, Hohnloser SH, Diener HC, Franzosi MG, Huber K, Reilly P, Varrone J PMID: 22271859 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643068 Tue, 24 Jan 2012 05:00:00 +0100 5643068 http://www.medworm.com/index.php?rid=5643067&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22275500%26dopt%3DAbstract Authors: Cooke JP Abstract At the level of the capillaries, the systemic circulation loses about 2-4 liters of fluid and about 100g of protein into the interstitium daily. This ultrafiltrate of the systemic capillaries is returned to the circulatory system by the lymphatics. The lymphatic vasculature is highly specialized to perform this service, beginning with the blind-ended lymphatic capillaries. These vessels are highly permeable to protein, fluid and even cells, due to fenestrations in their basement membrane, and discontinuous button-like junctions rather than tight intercellular junctions as observed in the systemic capillaries(1). The lymphatic capillaries merge into collectors and larger lymphatic conduits that are invested with vascular smooth muscle (capable of contracti... Circulation journals http://www.medworm.com/rss/comments.php?id=5643067 Tue, 24 Jan 2012 05:00:00 +0100 5643067 http://www.medworm.com/index.php?rid=5643066&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22275501%26dopt%3DAbstract CONCLUSIONS: These in vitro and animal studies demonstrate that 9-cisRA potently activates lymphangiogenesis and promotes lymphatic regeneration in an experimental lymphedema model, presenting it as a promising novel therapeutic agent to treat human lymphedema patients. PMID: 22275501 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5643066 Tue, 24 Jan 2012 05:00:00 +0100 5643066 http://www.medworm.com/index.php?rid=5643081&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22271754%26dopt%3DAbstract Evaluating Parents and Adult Caregivers as "Agents of Change" for Treating Obese Children: Evidence for Parent Behavior Change Strategies and Research Gaps: A Scientific Statement From the American Heart Association. Circulation. 2012 Jan 23; Authors: Faith MS, Van Horn L, Appel LJ, Burke LE, Carson JA, Franch HA, Jakicic JM, Kral TV, Odoms-Young A, Wansink B, Wylie-Rosett J, Abstract This scientific statement addresses parents and adult caregivers (PACs) as "agents of change" for obese children, evaluating the strength of evidence that particular parenting strategies can leverage behavior change and reduce positive energy balance in obese youth. The statement has 3 specific aims. The first is to review core behavior change strategies for PACs as used in family-based treat... Circulation journals http://www.medworm.com/rss/comments.php?id=5643081 Mon, 23 Jan 2012 05:00:00 +0100 5643081 http://www.medworm.com/index.php?rid=5625452&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22265908%26dopt%3DAbstract CONCLUSIONS: This study identifies CHOP-10 as an important transcription factor modulating vessel formation and maturation. PMID: 22265908 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625452 Fri, 20 Jan 2012 05:00:00 +0100 5625452 http://www.medworm.com/index.php?rid=5625451&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22265909%26dopt%3DAbstract CONCLUSIONS: Increased PLC-δ1 activity enhances coronary vasomotility such as seen in patients with CSA. PMID: 22265909 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625451 Fri, 20 Jan 2012 05:00:00 +0100 5625451 http://www.medworm.com/index.php?rid=5625450&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22267844%26dopt%3DAbstract Authors: Levine GN, Steinke EE, Bakaeen FG, Bozkurt B, Cheitlin MD, Conti JB, Foster E, Jaarsma T, Kloner RA, Lange RA, Lindau ST, Maron BJ, Moser DK, Ohman EM, Seftel AD, Stewart WJ, PMID: 22267844 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625450 Thu, 19 Jan 2012 05:00:00 +0100 5625450 http://www.medworm.com/index.php?rid=5625461&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261192%26dopt%3DAbstract CONCLUSIONS: In women with suspected preeclampsia presenting at <34 weeks, circulating sFlt1/PlGF ratio predicts adverse outcomes occurring within two weeks. The accuracy of this test is substantially better than current approaches and may be useful in risk stratification and management. Additional studies are warranted to validate these findings. PMID: 22261192 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625461 Wed, 18 Jan 2012 05:00:00 +0100 5625461 http://www.medworm.com/index.php?rid=5625460&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261193%26dopt%3DAbstract Authors: Deleon KY, de Castro Brás L, Lange RA, Lindsey ML Abstract Prolonged myocardial ischemia leads to myocytenecrosis, which initiates a localized inflammatory response that catabolizes the cellular debris and initiates deposition of extracellular matrix (ECM) proteins.(1) In addition to providing a vital structural framework for the three-dimensional organization of cells, the ECM determines the physical properties of biological tissues and acts as a dynamic microenvironment for cellular signaling. A number of cardiac diseases, including myocardial ischemia and reperfusion (I/R), are associated with qualitative and quantitative alterations in ECM proteins.(2) Understanding ECM changes is important for identifying factors that tip the balance between favorable reparative remo... Circulation journals http://www.medworm.com/rss/comments.php?id=5625460 Wed, 18 Jan 2012 05:00:00 +0100 5625460 http://www.medworm.com/index.php?rid=5625459&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261194%26dopt%3DAbstract CONCLUSIONS: Our findings reveal a bio-signature of early and late stage ECM remodeling after myocardial ischemia-reperfusion injury, which may have clinical utility as prognostic markers and modifiable targets for drug discovery. PMID: 22261194 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625459 Wed, 18 Jan 2012 05:00:00 +0100 5625459 http://www.medworm.com/index.php?rid=5625458&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261195%26dopt%3DAbstract CONCLUSIONS: Altogether, our results show a direct relationship between PCSK9 and atherosclerosis. PCSK9 overexpression is pro-atherogenic, while its absence is protective. PMID: 22261195 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625458 Wed, 18 Jan 2012 05:00:00 +0100 5625458 http://www.medworm.com/index.php?rid=5625457&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261196%26dopt%3DAbstract CONCLUSIONS: Collectively, this is the first study demonstrating that hESC-CMs and iPSC-CMs exhibit BRV andpower law behavior as in humans, thus supporting the potential capability of these cell sources to serve as biological pacemakers.Our ability to generate sinoatrial-compatible spontaneous cardiomyocytes from the patient's own hair (via keratinocytes-derived iPSC), thus eliminating the critical need for immunosuppression, renders these myocytes an attractive cell source as biological pacemakers. PMID: 22261196 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625457 Wed, 18 Jan 2012 05:00:00 +0100 5625457 http://www.medworm.com/index.php?rid=5625456&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261197%26dopt%3DAbstract Authors: Ripplinger CM, Bers DM Abstract In healthy individuals, the sinoatrial node (SAN) is responsible for initiating excitation over 100,000 times per day. As with all cardiac pacemaking cells in the specialized conduction system, SAN automaticity is driven by diastolic depolarization via several redundant pathways to ensure that the heart beats. Key cellular mechanisms include the hyperpolarization-activated inward current I(f) and the "Ca Clock" (inward Na/Ca exchange current activated by sarcoplasmic reticulum Ca(2+) release).(1) However, molecular, histological, electrophysiological, and in silico studies have revealed that the SAN is extremely complex and the redundant systems not only provide safety of pacemaking, but also allows for precise modulation of heart rate to ac... Circulation journals http://www.medworm.com/rss/comments.php?id=5625456 Wed, 18 Jan 2012 05:00:00 +0100 5625456 http://www.medworm.com/index.php?rid=5625455&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261198%26dopt%3DAbstract CONCLUSIONS: In patients with normal baseline LV ejection fraction, worsening of diastolic function is an independent predictor of mortality. PMID: 22261198 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625455 Wed, 18 Jan 2012 05:00:00 +0100 5625455 http://www.medworm.com/index.php?rid=5625454&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261199%26dopt%3DAbstract Authors: Kitzman DW, Little WC Abstract To provide for tissue perfusion without pulmonary congestion, the left ventricle (LV) must eject an adequate stroke volume at arterial pressure (systolic function) and fill without requiring an abnormally increased left atrial pressure (diastolic function). Systolic and diastolic function must be adequate to meet the needs of the body both at rest and during stress (reserve capacity). (SELECT FULL TEXT TO CONTINUE). PMID: 22261199 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625454 Wed, 18 Jan 2012 05:00:00 +0100 5625454 http://www.medworm.com/index.php?rid=5625453&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22261200%26dopt%3DAbstract CONCLUSIONS: The use of a PPI was independently associated with a higher rate of CV events in ACS patients receiving clopidogrel. However, a similar association was observed between CV events and PPI use during ticagrelor treatment and with other non-PPI GI treatment. Therefore, in the PLATO trial, the association between PPI use and adverse events may be due to confounding, with PPI use more of a marker for, than a cause of, higher rates of CV events. CLINICAL TRIAL REGISTRATION INFORMATION: http://www.clinicatrials.gov; NCT00391872. PMID: 22261200 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625453 Wed, 18 Jan 2012 05:00:00 +0100 5625453 http://www.medworm.com/index.php?rid=5625467&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249527%26dopt%3DAbstract Authors: Moukarbel GV, Bhatt DL PMID: 22249527 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625467 Tue, 17 Jan 2012 05:00:00 +0100 5625467 http://www.medworm.com/index.php?rid=5625466&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249528%26dopt%3DAbstract Authors: Zimetbaum P PMID: 22249528 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625466 Tue, 17 Jan 2012 05:00:00 +0100 5625466 http://www.medworm.com/index.php?rid=5625465&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249529%26dopt%3DAbstract Authors: Del Trigo M, Jimenez-Quevedo P, Fernandez-Golfin C, Vaño E, Delgado-Bolton R, Alfonso F, Gonzalo N, Kallmeyer A, Montes L, Escribano N, Hernandez-Antolin R, Macaya C PMID: 22249529 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625465 Tue, 17 Jan 2012 05:00:00 +0100 5625465 http://www.medworm.com/index.php?rid=5625464&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249530%26dopt%3DAbstract Authors: Karakulak UN, Kose IC, Evranos B, Okutucu S, Hazirolan T, Aytemir K, Oto A PMID: 22249530 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625464 Tue, 17 Jan 2012 05:00:00 +0100 5625464 http://www.medworm.com/index.php?rid=5625463&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249531%26dopt%3DAbstract Authors: Shah AM, Solomon SD PMID: 22249531 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625463 Tue, 17 Jan 2012 05:00:00 +0100 5625463 http://www.medworm.com/index.php?rid=5625462&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249532%26dopt%3DAbstract Authors: Abstract The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read manuscripts published on the topic of atherosclerosis in 2010 and 2011. PMID: 22249532 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625462 Tue, 17 Jan 2012 05:00:00 +0100 5625462 http://www.medworm.com/index.php?rid=5625468&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22247494%26dopt%3DAbstract CONCLUSIONS: These findings demonstrate a central role for increased gremlin in hypoxia-induced pulmonary vascular remodeling and the increased pulmonary vascular resistance in hypoxic pulmonary hypertension. High levels of basal gremlin expression in the lung may account for the unique vulnerability of the pulmonary circulation to heterozygous mutations of BMPR2 in pulmonary arterial hypertension. PMID: 22247494 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625468 Fri, 13 Jan 2012 05:00:00 +0100 5625468 http://www.medworm.com/index.php?rid=5625470&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22247492%26dopt%3DAbstract CONCLUSIONS: The co-existence of low birth weight, small head circumference and parental history of overweight or obesity may be useful for detection of children at risk of developing MetS in adolescence. PMID: 22247492 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625470 Thu, 12 Jan 2012 05:00:00 +0100 5625470 http://www.medworm.com/index.php?rid=5625469&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22247493%26dopt%3DAbstract CONCLUSIONS: Primary repair in neonates and young infants potentially provides successful WM development in CHD patients. Cardiac surgery during this susceptible period should avoid ischemia-reperfusion injury and minimize inflammation to prevent long-term WM-related neurological impairment. PMID: 22247493 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625469 Thu, 12 Jan 2012 05:00:00 +0100 5625469 http://www.medworm.com/index.php?rid=5625472&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22238227%26dopt%3DAbstract CONCLUSIONS: VGF is common after CABG surgery and is associated with repeat revascularization, but not with death and/or MI. Further investigations are needed to evaluate therapies and strategies for decreasing VGF to improve outcomes in patients undergoing CABG surgery. PMID: 22238227 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625472 Wed, 11 Jan 2012 05:00:00 +0100 5625472 http://www.medworm.com/index.php?rid=5625471&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22238228%26dopt%3DAbstract CONCLUSIONS: In this long-term observational, propensity score matched study, percutaneous PFO closure was more effective than medical treatment for secondary prevention of recurrent cerebrovascular events among patients with PFO related TIA or stroke. PMID: 22238228 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5625471 Wed, 11 Jan 2012 05:00:00 +0100 5625471 http://www.medworm.com/index.php?rid=5579483&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22230481%26dopt%3DAbstract CONCLUSIONS: Grief over the death of a significant person was associated with an acutely increased risk of MI in the subsequent days. The impact may be greatest among individuals at high cardiovascular risk. PMID: 22230481 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5579483 Mon, 09 Jan 2012 05:00:00 +0100 5579483 http://www.medworm.com/index.php?rid=5579482&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22230482%26dopt%3DAbstract Authors: Lerner EB, Rea TD, Bobrow BJ, Acker JE, Berg RA, Brooks SC, Cone DC, Gay M, Gent LM, Mears G, Nadkarni VM, O'Connor RE, Potts J, Sayre MR, Swor RA, Travers AH, PMID: 22230482 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5579482 Mon, 09 Jan 2012 05:00:00 +0100 5579482 http://www.medworm.com/index.php?rid=5579481&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22230483%26dopt%3DAbstract CONCLUSIONS: sPLA(2) mass independently predicts death during a 16 week period following ACS. High dose atorvastatin significantly reduces sPLA(2) and Lp-PLA(2) mass and activity after ACS and mitigates the risk of death associated with sPLA(2) mass. Atorvastatin may exert anti-inflammatory effects on phospholipases that contribute to its therapeutic benefit after ACS. PMID: 22230483 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5579481 Mon, 09 Jan 2012 05:00:00 +0100 5579481 http://www.medworm.com/index.php?rid=5579480&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22230484%26dopt%3DAbstract CONCLUSIONS: The overall 5-years arterial complication rate was of 44%. Biological inflammation increased the likelihood of complications after revascularization in patients with TA. PMID: 22230484 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5579480 Mon, 09 Jan 2012 05:00:00 +0100 5579480 http://www.medworm.com/index.php?rid=5579485&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22223428%26dopt%3DAbstract CONCLUSIONS: These results indicate that administration of SDF1-GPVI may be a promising strategy to treat MI to promote myocardial repair and to preserve cardiac function. PMID: 22223428 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5579485 Thu, 05 Jan 2012 05:00:00 +0100 5579485 http://www.medworm.com/index.php?rid=5579484&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22223429%26dopt%3DAbstract CONCLUSIONS: Both lower and higher serum sodium levels are independently associated with higher mortality in patients with non-dialysis dependent CKD, irrespective of the presence of absence of congestive heart failure. PMID: 22223429 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5579484 Thu, 05 Jan 2012 05:00:00 +0100 5579484 http://www.medworm.com/index.php?rid=5563538&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215856%26dopt%3DAbstract CONCLUSIONS: There was a non-significant increase in MI with dabigatran compared to warfarin, but other myocardial ischemic events were not increased. Treatment effects of dabigatran are consistent in patients at higher and lower risk of myocardial ischemic events. CLINICAL TRIAL REGISTRATION INFORMATION: ClinicalTrials.gov; NCT 00262600. PMID: 22215856 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563538 Tue, 03 Jan 2012 05:00:00 +0100 5563538 http://www.medworm.com/index.php?rid=5563537&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215857%26dopt%3DAbstract CONCLUSIONS: TMEM16A CaCC is a negative regulator of cell proliferation. Downregulation of CaCC may play an important role in hypertension-induced cerebrovascular remodeling, suggesting modification of the activity of CaCC may be a novel therapeutic strategy for hypertension-associated cardiovascular diseases, such as stroke. PMID: 22215857 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563537 Tue, 03 Jan 2012 05:00:00 +0100 5563537 http://www.medworm.com/index.php?rid=5563536&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215858%26dopt%3DAbstract Authors: Obeyesekere M, Gula LJ, Skanes AC, Leong-Sit P, Klein GJ Abstract In 1930, Dr. Louis Wolff, Sir John Parkinson and Paul Dudley White described a case series of 11 patients with a syndrome that now bears their name(1). The first patient with a short PR interval, ventricular pre-excitation and supraventricular tachycardia (SVT) was described by Cohn and Fraser in 1913(1). Wood et al postulated the accessory pathway (AP) as its anatomical substrate in 1942 and a large population series reported the prevalence of pre-excitation to be 0.15% in 1962(2). Reports in 1971 and 1979 described sudden cardiac death (SCD) in WPW patients related to atrial fibrillation (AF) conducting rapidly over the AP with a short refractory period that deteriorated into ventricular fibrillation (VF)(... Circulation journals http://www.medworm.com/rss/comments.php?id=5563536 Tue, 03 Jan 2012 05:00:00 +0100 5563536 http://www.medworm.com/index.php?rid=5563535&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215859%26dopt%3DAbstract CONCLUSIONS: Symptomatic patients with WPW syndrome generally have a good outcome and predictors of malignant arrhythmias are similar to those reported for asymptomatic patients with ventricular preexcitation. PMID: 22215859 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563535 Tue, 03 Jan 2012 05:00:00 +0100 5563535 http://www.medworm.com/index.php?rid=5563534&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215889%26dopt%3DAbstract Authors: PMID: 22215889 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563534 Tue, 03 Jan 2012 05:00:00 +0100 5563534 http://www.medworm.com/index.php?rid=5563533&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215890%26dopt%3DAbstract Authors: Granger CB, Armaganijan LV PMID: 22215890 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563533 Tue, 03 Jan 2012 05:00:00 +0100 5563533 http://www.medworm.com/index.php?rid=5563532&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215891%26dopt%3DAbstract Authors: Ansell J PMID: 22215891 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563532 Tue, 03 Jan 2012 05:00:00 +0100 5563532 http://www.medworm.com/index.php?rid=5563531&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215892%26dopt%3DAbstract Authors: Stuart-Shor EM, Berra KA, Kamau MW, Kumanyika SK PMID: 22215892 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563531 Tue, 03 Jan 2012 05:00:00 +0100 5563531 http://www.medworm.com/index.php?rid=5563530&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215893%26dopt%3DAbstract Authors: Gerber BL, Pasquet A, El Khoury G, Verhelst R, Vanoverschelde JL, Watremez C, Vancraeynest D PMID: 22215893 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563530 Tue, 03 Jan 2012 05:00:00 +0100 5563530 http://www.medworm.com/index.php?rid=5563529&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215894%26dopt%3DAbstract Authors: , Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB, , PMID: 22215894 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563529 Tue, 03 Jan 2012 05:00:00 +0100 5563529 http://www.medworm.com/index.php?rid=5563528&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215895%26dopt%3DAbstract Authors: Butera G, Salvia J, Carminati M PMID: 22215895 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563528 Tue, 03 Jan 2012 05:00:00 +0100 5563528 http://www.medworm.com/index.php?rid=5563527&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215896%26dopt%3DAbstract Authors: Abstract The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read manuscripts published on the topic of aortic disease in 2010 and 2011. PMID: 22215896 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563527 Tue, 03 Jan 2012 05:00:00 +0100 5563527 http://www.medworm.com/index.php?rid=5563526&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215897%26dopt%3DAbstract Letter by Van Laecke and Vanholder Regarding Article, "Risk of Recurrent Cardiac Events After Onset of Menopause in Women With Congenital Long-QT Syndrome Types 1 and 2". Circulation. 2012 Jan 3;125(1):e236 Authors: Van Laecke S, Vanholder R PMID: 22215897 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563526 Tue, 03 Jan 2012 05:00:00 +0100 5563526 http://www.medworm.com/index.php?rid=5563525&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215898%26dopt%3DAbstract Letter to the editor by kohrmann and schellinger regarding article, "current status of endovascular stroke treatment". Circulation. 2012 Jan 3;125(1):e237 Authors: Köhrmann M, Schellinger PD PMID: 22215898 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563525 Tue, 03 Jan 2012 05:00:00 +0100 5563525 http://www.medworm.com/index.php?rid=5563524&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215899%26dopt%3DAbstract Letter by Ravensbergen et al Regarding Article, "Long-Term Recording of Cardiac Arrhythmias With an Implantable Cardiac Monitor in Patients With Reduced Ejection Fraction After Acute Myocardial Infarction: The Cardiac Arrhythmias and Risk Stratification After Acute Myocardial Infarction (CARISMA) Study". Circulation. 2012 Jan 3;125(1):e239 Authors: Ravensbergen NJ, Verhagen HJ, De Melis M PMID: 22215899 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563524 Tue, 03 Jan 2012 05:00:00 +0100 5563524 http://www.medworm.com/index.php?rid=5563539&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22207715%26dopt%3DAbstract CONCLUSIONS: Substituting CNI with SRL as primary immunosuppressant attenuates long term CAV progression and may improve long-term allograft survival due to favorable coronary remodeling. Because of the lack of randomization, and retrospective nature of our analysis, the differences in outcome should be interpreted cautiously and prospective clinical trials would be required. PMID: 22207715 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5563539 Thu, 29 Dec 2011 05:00:00 +0100 5563539 http://www.medworm.com/index.php?rid=5551748&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22203692%26dopt%3DAbstract CONCLUSIONS: The postnatal murine aorta contains rare multipotent HPCs/HSCs and is selectively enriched with Sca-1(+) monocyte/macrophage precursors. These populations may represent novel, local vascular sources of inflammatory cells. PMID: 22203692 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5551748 Tue, 27 Dec 2011 05:00:00 +0100 5551748 http://www.medworm.com/index.php?rid=5551747&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22203693%26dopt%3DAbstract Authors: Yoder MC Abstract The stem cell theory of hematopoiesis predicts that all mature blood cell lineages circulating in the bloodstream or resident in tissues, arise via a hierarchy of hematopoietic progenitor cell (HPC) intermediates that are ultimately derived from hematopoietic stem cells (HSC). In the adult human subject, bone marrow resident HSC and HPC generate billions of circulating blood cells daily, ranging from the short-lived neutrophils and platelets to long-lived B and T lymphocytes and monocyte-macrophages. Recent interest in the roles of macrophages as modulators of angiogenesis(1) and as participants in atheroma formation(2) highlight the need to better understand the mechanisms of recruitment and retention of macrophages and their progenitor precursors within... Circulation journals http://www.medworm.com/rss/comments.php?id=5551747 Tue, 27 Dec 2011 05:00:00 +0100 5551747 http://www.medworm.com/index.php?rid=5551746&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22203694%26dopt%3DAbstract CONCLUSIONS: Late adverse events such as very late ST and late TLR are the continuous hazard lasting at least up to 5 years after implantation of the first generation drug-eluting stents (SES), which should be the targets in developing improved coronary stents. PMID: 22203694 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5551746 Tue, 27 Dec 2011 05:00:00 +0100 5551746 http://www.medworm.com/index.php?rid=5551745&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22203695%26dopt%3DAbstract Authors: Faxon DP Abstract Randomized trials and registries have clearly demonstrated that drug-eluting stents (DES) are effective in reducing restenosis(1,2). Following their introduction and an initial period of unbridled enthusiasm, it was recognized that there was a significant increase in very late stent thrombosis (VLST) when compared to bare metal stents (BMS) and this late complication has been the subject of continued concern and intensive investigation. Very late ST is fortunately infrequent but it is associated with very high rates of death and myocardial infarction. Understanding the frequency, duration and potential mechanisms of VSLT have been hampered by the lack of large studies where low frequency events can be more accurately determined and evaluated. Randomized t... Circulation journals http://www.medworm.com/rss/comments.php?id=5551745 Tue, 27 Dec 2011 05:00:00 +0100 5551745 http://www.medworm.com/index.php?rid=5551744&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22203696%26dopt%3DAbstract CONCLUSIONS: Patients with type II DM undergoing bioprosthetic valve implantation are at high risk of early and long-term mortality as well as of SVD. PMID: 22203696 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5551744 Tue, 27 Dec 2011 05:00:00 +0100 5551744 http://www.medworm.com/index.php?rid=5537073&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fcmd%3DSearch%26db%3Dpubmed%26term%3D%28%2520%28%2522Circulation%2522%255Bta%255D%29%2520AND%2520%25222011%252F11%252F19%252015.54%2522%255BEDAT%255D%253A%25222011%252F12%252F24%252016.24%2522%255BEDAT%255D%29 101 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "Circulation"[ta] These pubmed results were generated on 2011/12/24PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources. (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5537073 Sat, 24 Dec 2011 21:24:02 +0100 5537073 http://www.medworm.com/index.php?rid=5424689&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22095826%26dopt%3DAbstract CONCLUSIONS: -These prevalence estimates of CV health represent a starting point from which effectiveness of efforts to promote CV health and prevent CV disease can be monitored and compared in U.S. adult populations. PMID: 22095826 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424689 Thu, 17 Nov 2011 05:00:00 +0100 5424689 http://www.medworm.com/index.php?rid=5424688&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22095827%26dopt%3DAbstract CONCLUSIONS: -Niacin activates HO-1 in vivo and in vitro. Induction of HO-1 may be partly responsible for the vascular protective properties of niacin. PMID: 22095827 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424688 Thu, 17 Nov 2011 05:00:00 +0100 5424688 http://www.medworm.com/index.php?rid=5424687&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22095828%26dopt%3DAbstract CONCLUSIONS: -Physicians who implant more ICDs have lower rates of procedural complications and in-hospital mortality, independent of hospital procedure volume, physician specialty, and ICD type. PMID: 22095828 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424687 Thu, 17 Nov 2011 05:00:00 +0100 5424687 http://www.medworm.com/index.php?rid=5424686&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22095829%26dopt%3DAbstract CONCLUSIONS: -Derivation of vasculogenic and multipotent pericytes from hPSC can be used for the development of vasculogenic models using multiple vasculogenic cell types for basic research and drug screening and can contribute to angiogenic regenerative medicine. PMID: 22095829 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424686 Thu, 17 Nov 2011 05:00:00 +0100 5424686 http://www.medworm.com/index.php?rid=5424685&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22095830%26dopt%3DAbstract Authors: Péault B Abstract In this issue of Circulation, Dar and collaborators report the healing of ischemic limbs in athymic mice bymultipotent progenitors derived from human embryonic stem cells orreprogrammed adult cells. So far, nothing really original; the excitement comes from the demonstration that these ES- and iPS-cell derived regenerative units exhibit the features of vascular pericytes(1). These observations are timely and remarkable inasmuch as the blood vessel, far away from a mere conduit, has lately gained nobility in the eyes of stem cell biologists for its recognized contribution to diverse cell lineages. On the one hand, it is now well accepted that, from fish to humans, specialized "blood-forming" endothelial cells in thedorsal aortaand, most certainly, other o... Circulation journals http://www.medworm.com/rss/comments.php?id=5424685 Thu, 17 Nov 2011 05:00:00 +0100 5424685 http://www.medworm.com/index.php?rid=5424695&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090163%26dopt%3DAbstract CONCLUSIONS: -Positron emission tomography is a novel, feasible and repeatable approach to thee valuation of valvular calcification and inflammation in patients with aortic stenosis. The frequency and magnitude of increased tracer activity correlates with disease severity, and is strongest for 18F-NaF. Clinical Trial Registration Information-ClinicalTrials.gov; Reference Number: NCT01358513. PMID: 22090163 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424695 Wed, 16 Nov 2011 05:00:00 +0100 5424695 http://www.medworm.com/index.php?rid=5424694&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090164%26dopt%3DAbstract Authors: Aikawa E, Otto CM Abstract Outcome measures in patients with aortic stenosisClinical trials of medical therapy to prevent progression in calcific aortic valve disease (CAVD) are hampered by the lack of sensitive measures of disease activity in the valve leaflets. Although the long-term goal of therapy is to prevent adverse cardiovascular outcomes, including mortality and aortic valve replacement, these endpoints have several limitations. First, the "hard" endpoint of mortality is frequently impacted by comorbid conditions. Patients with CAVD typically are elderly with a high prevalence of coronary and noncardiac disease so that isolating the effect of valve obstruction on survival is problematic. Second, the endpoint of valve replacement for symptom onset reflects consider... Circulation journals http://www.medworm.com/rss/comments.php?id=5424694 Wed, 16 Nov 2011 05:00:00 +0100 5424694 http://www.medworm.com/index.php?rid=5424693&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090165%26dopt%3DAbstract Authors: Chockalingam P, Wilde AA Abstract The role of channelopathies in the pathogenesis of sudden cardiac death (SCD) in patients with structurally normal hearts is a rapidly evolving story.(1) Many ion channels are involved, including loss-of-function sodium channelopathies of which the phenotypic spectrum ranges from lethal arrhythmias to asymptomatic carriers and includes Brugada Syndrome (BrS), cardiac conduction disease, sick sinus syndrome, atrial fibrillation and dilated cardiomyopathy. BrS, characterized by right precordial ST elevation on the electrocardiogram, is frequently associated with conduction delay, potentially lethal arrhythmias, and a positive family history of sudden premature death. BrS is estimated to be responsible for approximately 4% of all sudden death... Circulation journals http://www.medworm.com/rss/comments.php?id=5424693 Wed, 16 Nov 2011 05:00:00 +0100 5424693 http://www.medworm.com/index.php?rid=5424692&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090166%26dopt%3DAbstract CONCLUSIONS: -Infants having rapid ventricular tachycardia and conduction abnormalities in the absence of structural or metabolic abnormalities are likely to have disease-causing mutations in cardiac depolarizing channels. PMID: 22090166 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424692 Wed, 16 Nov 2011 05:00:00 +0100 5424692 http://www.medworm.com/index.php?rid=5424691&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090167%26dopt%3DAbstract CONCLUSIONS: . Unique identifier: NCT00128427. PMID: 22090167 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424691 Wed, 16 Nov 2011 05:00:00 +0100 5424691 http://www.medworm.com/index.php?rid=5424690&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090168%26dopt%3DAbstract CONCLUSIONS: . Unique identifier: NCT00132743. PMID: 22090168 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424690 Wed, 16 Nov 2011 05:00:00 +0100 5424690 http://www.medworm.com/index.php?rid=5424712&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083145%26dopt%3DAbstract Authors: Schwartz PJ, Crotti L PMID: 22083145 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424712 Tue, 15 Nov 2011 05:00:00 +0100 5424712 http://www.medworm.com/index.php?rid=5424711&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083146%26dopt%3DAbstract Authors: Derval N, Shah A, Jaïs P PMID: 22083146 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424711 Tue, 15 Nov 2011 05:00:00 +0100 5424711 http://www.medworm.com/index.php?rid=5424710&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083147%26dopt%3DAbstract Authors: Kremastinos DT, Farmakis D PMID: 22083147 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424710 Tue, 15 Nov 2011 05:00:00 +0100 5424710 http://www.medworm.com/index.php?rid=5424709&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083148%26dopt%3DAbstract This article reviews the basic pathophysiology of AF over a broad range of levels, touching on the tissue mechanisms that maintain the arrhythmia, the relationship between clinical presentation and basic mechanisms, ion channel and transporter abnormalities that lead to ectopic impulse formation, basic models and tissue determinants of reentry, ion channel determinants of reentry, the nature and roles of electric and structural remodeling, autonomic neural components, anatomic factors, interactions between atrial and ventricular functional consequences of AF, and the basic determinants of atrial thromboembolism. We then review the potential implications of the basic pathophysiology of the arrhythmia for its management. We first discuss consequences for improved rhythm control pharmacothera... Circulation journals http://www.medworm.com/rss/comments.php?id=5424709 Tue, 15 Nov 2011 05:00:00 +0100 5424709 http://www.medworm.com/index.php?rid=5424708&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083149%26dopt%3DAbstract Authors: Padalino MA, Vida VL, Bhattarai A, Reffo E, Milanesi O, Thiene G, Stellin G, Basso C PMID: 22083149 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424708 Tue, 15 Nov 2011 05:00:00 +0100 5424708 http://www.medworm.com/index.php?rid=5424707&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083150%26dopt%3DAbstract Authors: Magnoni M, Turri C, Roghi A, Merlanti B, Maseri A PMID: 22083150 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424707 Tue, 15 Nov 2011 05:00:00 +0100 5424707 http://www.medworm.com/index.php?rid=5424706&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083151%26dopt%3DAbstract Authors: Cheng S, Vasan RS PMID: 22083151 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424706 Tue, 15 Nov 2011 05:00:00 +0100 5424706 http://www.medworm.com/index.php?rid=5424705&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083152%26dopt%3DAbstract Authors: Abstract The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read manuscripts published on the topic of epidemiology and prevention in 2009 and 2010. PMID: 22083152 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424705 Tue, 15 Nov 2011 05:00:00 +0100 5424705 http://www.medworm.com/index.php?rid=5424704&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083153%26dopt%3DAbstract Letter by falk regarding article, "an unusual heart failure: cardiac amyloidosis due to light chain myeloma". Circulation. 2011 Nov 15;124(20):e534 Authors: Falk RH PMID: 22083153 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424704 Tue, 15 Nov 2011 05:00:00 +0100 5424704 http://www.medworm.com/index.php?rid=5424703&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22083154%26dopt%3DAbstract Letter by anyfanti et Al regarding article, "effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study". Circulation. 2011 Nov 15;124(20):e536 Authors: Anyfanti P, Gkaliagkousi E, Douma S PMID: 22083154 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424703 Tue, 15 Nov 2011 05:00:00 +0100 5424703 http://www.medworm.com/index.php?rid=5424702&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22086875%26dopt%3DAbstract CONCLUSIONS: -These data showed that ANGPTL4 might constitute a relevant target for therapeutic vasculoprotection aimed at counteracting the effects of VEGF, thus being crucial for preventing no-reflow and conferring secondary cardioprotection during AMI. PMID: 22086875 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424702 Tue, 15 Nov 2011 05:00:00 +0100 5424702 http://www.medworm.com/index.php?rid=5424701&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22086876%26dopt%3DAbstract CONCLUSIONS: -GSK-3α confers resistance to ischemic injury at least in part via limiting apoptosis. Loss of GSK-3α promotes ischemic injury, increases risk of cardiac rupture, accentuates post-MI remodeling and LV dysfunction, and increases the progression to heart failure. These findings are in striking contrast to multiple prior reports in which deletion or inhibition of GSK-3β is protective. PMID: 22086876 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424701 Tue, 15 Nov 2011 05:00:00 +0100 5424701 http://www.medworm.com/index.php?rid=5424700&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22086877%26dopt%3DAbstract Conclusions-The repair of thoracoabdominal pathologies by means of hybrid procedures in patients who are poor surgical candidates is still associated with significant morbidity and mortality rates. Future studies may substantiate whether the technique is amenable to amelioration and improvement. PMID: 22086877 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424700 Tue, 15 Nov 2011 05:00:00 +0100 5424700 http://www.medworm.com/index.php?rid=5424699&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22086878%26dopt%3DAbstract CONCLUSIONS: -Allogeneic CDC transplantation without immunosuppression is safe, promotes cardiac regeneration and improves heart function in a rat myocardial infarction model, mainly through stimulation of endogenous repair mechanisms. This indirect mechanism of action rationalizes the persistence of benefit despite the evanescence of transplanted cell survival. This work motivates the testing of allogeneic human CDCs as a potential off-the-shelf product for cellular cardiomyoplasty. PMID: 22086878 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424699 Tue, 15 Nov 2011 05:00:00 +0100 5424699 http://www.medworm.com/index.php?rid=5424698&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22086879%26dopt%3DAbstract CONCLUSIONS: -This study suggests that, in elderly patients with SUO and positive ATP tests, active dual-chamber pacing reduces syncope recurrence risk by 75% (95% CI 44% to 88%).Clinical Trial Registration Information-http://www.controlled-trials.com/ISRCTN00029383; Unique Identifier: ISRCTN00029383. PMID: 22086879 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424698 Tue, 15 Nov 2011 05:00:00 +0100 5424698 http://www.medworm.com/index.php?rid=5424697&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22086880%26dopt%3DAbstract CONCLUSIONS: -In a rat model of CPR, a shorter duration of mild hypothermia induced rapidly and early following ROSC improved post-resuscitation microcirculation, myocardial and cerebral functions and survival equally or better than prolonged duration of hypothermia following resuscitation. PMID: 22086880 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424697 Tue, 15 Nov 2011 05:00:00 +0100 5424697 http://www.medworm.com/index.php?rid=5424696&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22086881%26dopt%3DAbstract CONCLUSIONS: -Utilizing the REVEAL Registry, we identified key predictors of survival in childhood PAH. Refining these prognostic parameters should help clinicians improve outcomes.Clinical Trial Registration Information-ClinicalTrials.gov; Identifier: NCT00370214. PMID: 22086881 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424696 Tue, 15 Nov 2011 05:00:00 +0100 5424696 http://www.medworm.com/index.php?rid=5424722&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082672%26dopt%3DAbstract Authors: Kowey PR, Crijns HJ, Aliot EM, Capucci A, Kulakowski P, Radzik D, Roy D, Connolly SJ, Hohnloser SH, Abstract BACKGROUND: . Unique identifier: NCT00993382. PMID: 22082672 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424722 Mon, 14 Nov 2011 05:00:00 +0100 5424722 http://www.medworm.com/index.php?rid=5424721&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082673%26dopt%3DAbstract CONCLUSIONS: . Unique identifier: NCT00662701. PMID: 22082673 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424721 Mon, 14 Nov 2011 05:00:00 +0100 5424721 http://www.medworm.com/index.php?rid=5424720&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082674%26dopt%3DAbstract Conclusions-These results, for the first time, establish Pak1 as a novel antihypertrophic regulator and suggest that it may be a potential therapeutic target for the treatment of cardiac hypertrophy and heart failure. PMID: 22082674 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424720 Mon, 14 Nov 2011 05:00:00 +0100 5424720 http://www.medworm.com/index.php?rid=5424719&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082675%26dopt%3DAbstract Conclusions-These data show that ARC, previously unlinked to pulmonary hypertension, is a critical determinant of vascular remodeling in this syndrome. PMID: 22082675 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424719 Mon, 14 Nov 2011 05:00:00 +0100 5424719 http://www.medworm.com/index.php?rid=5424718&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082676%26dopt%3DAbstract Authors: Balady GJ, Ades PA, Bittner VA, Franklin BA, Gordon NF, Thomas RJ, Tomaselli GF, Yancy CW PMID: 22082676 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424718 Mon, 14 Nov 2011 05:00:00 +0100 5424718 http://www.medworm.com/index.php?rid=5424717&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082677%26dopt%3DAbstract Conclusions-Heparin likely increases the maternal sFlt-1 through shedding of the extracellular domain of Flt-1 receptor. Our results imply that upregulation of circulating sFlt-1 immunoreactivity in pregnancy is not always associated with adverse outcomes, and that heparin's protective effects, if any, cannot be explained by promotion of angiogenesis. PMID: 22082677 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424717 Mon, 14 Nov 2011 05:00:00 +0100 5424717 http://www.medworm.com/index.php?rid=5424716&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082678%26dopt%3DAbstract Conclusions-ADMA profoundly impairs nitric oxide synthesis of PMNs, resulting in increased PMN adhesion to endothelial cells, superoxide generation, and release of MPO. In addition, MPO impairs DDAH1 activity. Our data reveal an ADMA-induced cycle of PMN activation, enhanced MPO release, and subsequent impairment of DDAH1 activity. These findings not only highlight so far unrecognized cytokine-like properties of ADMA but also identify MPO as a regulatory switch for ADMA bioavailability under inflammatory conditions. PMID: 22082678 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424716 Mon, 14 Nov 2011 05:00:00 +0100 5424716 http://www.medworm.com/index.php?rid=5424715&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082679%26dopt%3DAbstract Conclusions-Our results demonstrate an important role of SOCS3 regulation on cardiac gp130 signaling in the pathogenesis of contractile dysfunction and ventricular arrhythmias. PMID: 22082679 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424715 Mon, 14 Nov 2011 05:00:00 +0100 5424715 http://www.medworm.com/index.php?rid=5424714&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082680%26dopt%3DAbstract Conclusions-These data highlight a crucial role for MMP2 and neutral sphingomyelinase-2 in vasculopathy triggered by a humoral immune response and open new perspectives for preventing transplant vasculopathy with the use of MMP and neutral sphingomyelinase inhibitors, in addition to conventional immunosuppression. PMID: 22082680 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424714 Mon, 14 Nov 2011 05:00:00 +0100 5424714 http://www.medworm.com/index.php?rid=5424713&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22082681%26dopt%3DAbstract Conclusions-The hsTnT assay and the sPESI improve risk stratification of acute PE. Combination of both modalities may yield additive prognostic information and particularly identify possible candidates for out-of-hospital treatment. PMID: 22082681 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424713 Mon, 14 Nov 2011 05:00:00 +0100 5424713 http://www.medworm.com/index.php?rid=5424733&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064955%26dopt%3DAbstract Authors: Redline S, Foody J PMID: 22064955 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424733 Tue, 08 Nov 2011 05:00:00 +0100 5424733 http://www.medworm.com/index.php?rid=5424732&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064956%26dopt%3DAbstract Authors: Spinale FG PMID: 22064956 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424732 Tue, 08 Nov 2011 05:00:00 +0100 5424732 http://www.medworm.com/index.php?rid=5424731&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064957%26dopt%3DAbstract Authors: Engelberger RP, Kucher N PMID: 22064957 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424731 Tue, 08 Nov 2011 05:00:00 +0100 5424731 http://www.medworm.com/index.php?rid=5424730&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064958%26dopt%3DAbstract Authors: Mosca L, Barrett-Connor E, Kass Wenger N PMID: 22064958 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424730 Tue, 08 Nov 2011 05:00:00 +0100 5424730 http://www.medworm.com/index.php?rid=5424729&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064959%26dopt%3DAbstract Authors: Fukui D, Kai H, Takeuchi T, Gondo T, Oba T, Mawatari K, Tonai T, Matsuo Y, Ueda S, Niiyama H, Ueno T, Imaizumi T PMID: 22064959 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424729 Tue, 08 Nov 2011 05:00:00 +0100 5424729 http://www.medworm.com/index.php?rid=5424728&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064960%26dopt%3DAbstract Authors: Ehl NF, Sündermann S, Geyer R, Thies S, Epp C, Weilenmann D, Falk V, Joerg L, Rickli H, Maeder MT PMID: 22064960 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424728 Tue, 08 Nov 2011 05:00:00 +0100 5424728 http://www.medworm.com/index.php?rid=5424727&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064961%26dopt%3DAbstract Authors: Kinlay S PMID: 22064961 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424727 Tue, 08 Nov 2011 05:00:00 +0100 5424727 http://www.medworm.com/index.php?rid=5424726&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064962%26dopt%3DAbstract Authors: Abstract The following articles are being highlighted as part of Circulation's Topic Review series. This series will summarize the most important manuscripts, as selected by the editors, published in Circulation and the Circulation subspecialty journals. The studies included in this article represent the most read manuscripts published on the topic of epidemiology and prevention in 2009 and 2010. PMID: 22064962 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424726 Tue, 08 Nov 2011 05:00:00 +0100 5424726 http://www.medworm.com/index.php?rid=5424725&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064963%26dopt%3DAbstract Letter by vorpahl and kelm regarding article, "stent thrombogenicity early in high-risk interventional settings is driven by stent design and deployment and protected by polymer-drug coatings". Circulation. 2011 Nov 8;124(19):e511 Authors: Vorpahl M, Kelm M PMID: 22064963 [PubMed - in process] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424725 Tue, 08 Nov 2011 05:00:00 +0100 5424725 http://www.medworm.com/index.php?rid=5424724&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22068434%26dopt%3DAbstract Authors: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW PMID: 22068434 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424724 Tue, 08 Nov 2011 05:00:00 +0100 5424724 http://www.medworm.com/index.php?rid=5424723&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22068435%26dopt%3DAbstract Authors: Gersh BJ, Maron BJ, Bonow RO, Dearani JA, Fifer MA, Link MS, Naidu SS, Nishimura RA, Ommen SR, Rakowski H, Seidman CE, Towbin JA, Udelson JE, Yancy CW PMID: 22068435 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424723 Tue, 08 Nov 2011 05:00:00 +0100 5424723 http://www.medworm.com/index.php?rid=5424744&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064591%26dopt%3DAbstract CONCLUSIONS: . Unique identifier: NCT00095238. PMID: 22064591 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424744 Mon, 07 Nov 2011 05:00:00 +0100 5424744 http://www.medworm.com/index.php?rid=5424743&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064592%26dopt%3DAbstract Conclusion-PCI-related delays are extensive among patients transferred for X-PCI and are associated with poorer outcomes. No differential excess in mortality was seen with X-PCI compared with O-FT even with long PCI-related delays, but as XDB door-to-needle time times increase, the mortality advantage for X-PCI over O-FT declines. PMID: 22064592 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424743 Mon, 07 Nov 2011 05:00:00 +0100 5424743 http://www.medworm.com/index.php?rid=5424742&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064593%26dopt%3DAbstract Authors: Ekerstad N, Swahn E, Janzon M, Alfredsson J, Löfmark R, Lindenberger M, Carlsson P Abstract BACKGROUND: . Unique identifier: NCT01049997. PMID: 22064593 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424742 Mon, 07 Nov 2011 05:00:00 +0100 5424742 http://www.medworm.com/index.php?rid=5424741&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064594%26dopt%3DAbstract Conclusions-Mild hypertensive retinopathy is a risk factor for cardiovascular mortality independently of cardiovascular risk factors among men and women with and without hypertension. PMID: 22064594 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424741 Mon, 07 Nov 2011 05:00:00 +0100 5424741 http://www.medworm.com/index.php?rid=5424740&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064595%26dopt%3DAbstract Conclusions-Despite robust clinical trial evidence, a substantial number of patients with obstructive CAD remain untreated with statins. A small proportion were treated with nonstatin therapy, and 1 in 6 patients was simply untreated; half of the untreated patients had low-density lipoprotein cholesterol values <100 mg/dL. These findings illustrate important opportunities to improve lipid management in outpatients with obstructive CAD. PMID: 22064595 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424740 Mon, 07 Nov 2011 05:00:00 +0100 5424740 http://www.medworm.com/index.php?rid=5424739&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064596%26dopt%3DAbstract Conclusions-Our data show that ApoBDS-1 is a previously unrecognized peptide with robust proinflammatory activity, contributing to the disease-promoting effects of low-density lipoprotein in the pathogenesis of atherosclerosis. PMID: 22064596 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424739 Mon, 07 Nov 2011 05:00:00 +0100 5424739 http://www.medworm.com/index.php?rid=5424738&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064597%26dopt%3DAbstract Conclusions-Subtype-selective induction of m-calpain in aortic ECs during atherosclerotic progression is associated with proteolytic disorganization of VE-cadherin and proatherogenic hyperpermeability in cells. Thus, a strategy to selectively inhibit m-calpain may be useful for the therapeutic treatment of patients with atherosclerosis. PMID: 22064597 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424738 Mon, 07 Nov 2011 05:00:00 +0100 5424738 http://www.medworm.com/index.php?rid=5424737&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064598%26dopt%3DAbstract Authors: Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH PMID: 22064598 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424737 Mon, 07 Nov 2011 05:00:00 +0100 5424737 http://www.medworm.com/index.php?rid=5424736&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064599%26dopt%3DAbstract Authors: Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, Disesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD PMID: 22064599 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424736 Mon, 07 Nov 2011 05:00:00 +0100 5424736 http://www.medworm.com/index.php?rid=5424735&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064600%26dopt%3DAbstract Authors: Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, Cigarroa JE, Disesa VJ, Hiratzka LF, Hutter AM, Jessen ME, Keeley EC, Lahey SJ, Lange RA, London MJ, Mack MJ, Patel MR, Puskas JD, Sabik JF, Selnes O, Shahian DM, Trost JC, Winniford MD PMID: 22064600 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424735 Mon, 07 Nov 2011 05:00:00 +0100 5424735 http://www.medworm.com/index.php?rid=5424734&cid=s_36174_7_f&fid=36174&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22064601%26dopt%3DAbstract Authors: Levine GN, Bates ER, Blankenship JC, Bailey SR, Bittl JA, Cercek B, Chambers CE, Ellis SG, Guyton RA, Hollenberg SM, Khot UN, Lange RA, Mauri L, Mehran R, Moussa ID, Mukherjee D, Nallamothu BK, Ting HH PMID: 22064601 [PubMed - as supplied by publisher] (Source: Circulation) Circulation journals http://www.medworm.com/rss/comments.php?id=5424734 Mon, 07 Nov 2011 05:00:00 +0100 5424734