MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Climacteric' source. Sun, 21 Mar 2010 15:09:40 +0100 http://www.medworm.com/index.php?rid=3292222&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20166858%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 20166858 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3292222 Mon, 22 Feb 2010 00:12:18 +0100 3292222 http://www.medworm.com/index.php?rid=3292221&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20166859%26dopt%3DAbstract Conclusions TTP was effective in treating HSDD and improving sexual function in this study of naturally menopausal women with and without concurrent hormone therapy. PMID: 20166859 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3292221 Mon, 22 Feb 2010 00:12:13 +0100 3292221 http://www.medworm.com/index.php?rid=3292220&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20166860%26dopt%3DAbstract Authors: PMID: 20166860 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3292220 Mon, 22 Feb 2010 00:12:06 +0100 3292220 http://www.medworm.com/index.php?rid=3280693&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20151791%26dopt%3DAbstract Conclusion The health education program changed the cognitive actions of climacteric women, which resulted in continuously improved menopausal symptoms, quality of life and autonomic nervous system activity. PMID: 20151791 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3280693 Fri, 12 Feb 2010 00:00:00 +0100 3280693 http://www.medworm.com/index.php?rid=3280692&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20151792%26dopt%3DAbstract Conclusion Discontinuation of HT by reducing the daily dose of estrogen for a period of 2 or 4 months did not differ in its effect from that of abrupt cessation with regard to vasomotor symptoms. PMID: 20151792 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3280692 Fri, 12 Feb 2010 00:00:00 +0100 3280692 http://www.medworm.com/index.php?rid=3270357&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148729%26dopt%3DAbstract Conclusion The age of onset of menopause in Nigerian women with type 2 diabetes mellitus is comparable to the age that is commonly reported and the metabolic syndrome is highly prevalent in this group of women. PMID: 20148729 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3270357 Fri, 12 Feb 2010 00:00:00 +0100 3270357 http://www.medworm.com/index.php?rid=3265641&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20146574%26dopt%3DAbstract Conclusions This study shows that, in menopausal Italian women attending menopause clinics, sexual function is associated with the quality of sexual life in reproductive age, partner's health status, current quality of life, HT and occurrence of pain during and symptoms after sexual intercourse. PMID: 20146574 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3265641 Wed, 10 Feb 2010 00:00:00 +0100 3265641 http://www.medworm.com/index.php?rid=3259388&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20136410%26dopt%3DAbstract Conclusion This study shows that extended medical consultation promotes better compliance by lowering patient fears, while trusted authorities seem to be more convincing to patients on the benefits of HRT and therefore more effective, even if they do not take more time to talk to patients. PMID: 20136410 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3259388 Fri, 05 Feb 2010 00:00:00 +0100 3259388 http://www.medworm.com/index.php?rid=3259387&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20136411%26dopt%3DAbstract Conclusion Symptoms associated with menopause among Hispanic women differed by country of origin but not acculturation. Central American women appear to be at greatest risk for both vasomotor symptoms and vaginal dryness. PMID: 20136411 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3259387 Fri, 05 Feb 2010 00:00:00 +0100 3259387 http://www.medworm.com/index.php?rid=3247419&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20128664%26dopt%3DAbstract Conclusions Internal iliac artery ligation in the treatment of obstetric hemorrhage leads to dilation of the ovarian arteries and reversed flow in the ovarian branches of the uterine arteries. These change the blood supply to the ovaries and impair ovarian reserve. PMID: 20128664 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3247419 Wed, 03 Feb 2010 00:00:00 +0100 3247419 http://www.medworm.com/index.php?rid=3174740&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20067429%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 20067429 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3174740 Fri, 15 Jan 2010 15:48:13 +0100 3174740 http://www.medworm.com/index.php?rid=3174739&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20067430%26dopt%3DAbstract Authors: Kontos M, Agbaje OF, Rymer J, Fentiman IS Breast cancer survivors frequently experience severe hot flushes as a result of their treatment. This can adversely affect their quality of life, compliance with treatment and overall survival. To relieve vasomotor symptoms, a variety of drugs have been used including clonidine, gabapentin, selective serotonin reuptake inhibitors and selective norepinephrine reuptake inhibitors. Stellate ganglion block (SGB) has recently emerged as a new technique against hot flushes and preliminary studies report encouraging efficacy with minimal complications. Other approaches include various alternative treatments and, in a few cases, hormone replacement therapy (HRT). All randomized, controlled studies of drugs, hormone treatments and alternative t... Climacteric journals http://www.medworm.com/rss/comments.php?id=3174739 Fri, 15 Jan 2010 15:48:11 +0100 3174739 http://www.medworm.com/index.php?rid=3174738&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20067431%26dopt%3DAbstract Authors: PMID: 20067431 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3174738 Fri, 15 Jan 2010 15:48:08 +0100 3174738 http://www.medworm.com/index.php?rid=3174737&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20067432%26dopt%3DAbstract Authors: PMID: 20067432 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3174737 Fri, 15 Jan 2010 15:48:06 +0100 3174737 http://www.medworm.com/index.php?rid=3133945&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20039787%26dopt%3DAbstract Conclusion Postmenopausal women suffering severe vasomotor symptoms used more dietary supplements than the general population. They also had poorer self-reported health, but their medication use was similar to that of the general population. Acupuncture did not influence use of dietary supplements in the randomized intervention. PMID: 20039787 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3133945 Tue, 29 Dec 2009 00:00:00 +0100 3133945 http://www.medworm.com/index.php?rid=3101408&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20001563%26dopt%3DAbstract Conclusion The treatments had neutral effects on metabolic parameters in the study population. Excellent tolerability of both ultra-low doses resulted in high completion rates. PMID: 20001563 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3101408 Fri, 11 Dec 2009 00:00:00 +0100 3101408 http://www.medworm.com/index.php?rid=3101407&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20001564%26dopt%3DAbstract Conclusion The present findings suggest that gynecological status is associated with subjective sleep quality and objective sleep parameters in women with sleep complaints. PMID: 20001564 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3101407 Fri, 11 Dec 2009 00:00:00 +0100 3101407 http://www.medworm.com/index.php?rid=3101406&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20001565%26dopt%3DAbstract Authors: Haines CJ, Farrell E Hormone replacement therapy (HRT) remains the gold standard for the management of menopausal symptoms; however, HRT use has declined due to concerns over possible adverse side-effects. Approaches to menopause management are continually being revised and these extend beyond the control of recognized menopausal symptoms to encompass wider aspects of menopausal women's health. Hypertension and associated cardiovascular risk are particularly important unmet needs in postmenopausal women, especially in the Asia-Pacific region which has a rapidly aging population and bears around half of the global burden of cardiovascular disease, two-thirds of which has been attributed to elevated blood pressure. As first point of contact for women with menopausal symptoms, gy... Climacteric journals http://www.medworm.com/rss/comments.php?id=3101406 Fri, 11 Dec 2009 00:00:00 +0100 3101406 http://www.medworm.com/index.php?rid=3101405&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20001566%26dopt%3DAbstract Conclusion The data suggest that MTU stiffness is not related to either the administration of HT in postmenopausal women or to the nature of menopause. PMID: 20001566 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3101405 Fri, 11 Dec 2009 00:00:00 +0100 3101405 http://www.medworm.com/index.php?rid=3060053&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19958161%26dopt%3DAbstract Conclusions Menopause and its transition represent significant risk factors for the development of sexual dysfunction. FSD impacts greatly on a patient's quality of life. Consequently, it is receiving more attention thanks to the development of effective treatments. Non-pharmacological approaches should be used first, focusing on lifestyle and psychosexual therapy. If required, proven effective hormonal and non-hormonal therapeutic options are available. PMID: 19958161 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3060053 Thu, 03 Dec 2009 00:00:00 +0100 3060053 http://www.medworm.com/index.php?rid=3060052&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19958163%26dopt%3DAbstract Conclusions The use of and knowledge about HRT among women of Sarawak were found to be low in our study. The main sources of information about HRT are from friends/relatives and the mass media. Health-care providers should play an important role in promoting, counseling and health education regarding HRT needs to rectify these problems. PMID: 19958163 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3060052 Thu, 03 Dec 2009 00:00:00 +0100 3060052 http://www.medworm.com/index.php?rid=3052922&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19951084%26dopt%3DAbstract Conclusions Only two in ten patients effectively comply with CaVitD treatment after 1 year or more of its prescription. PMID: 19951084 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3052922 Tue, 01 Dec 2009 00:00:00 +0100 3052922 http://www.medworm.com/index.php?rid=2993082&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905898%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 19905898 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993082 Sun, 15 Nov 2009 11:30:34 +0100 2993082 http://www.medworm.com/index.php?rid=2993081&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905899%26dopt%3DAbstract This article reviews publications dating back more than a century describing investigations of the endometrium, including those examining the relationship between endometrial hyperplasia and carcinoma, the influence of estrogens on the endometrium, and strategies for protecting the endometrium from unopposed estrogen stimulation. Endometrial hyperplasia and carcinoma studies date from before 1900. The influence of endogenous estrogens on the endometrium became evident with observations of endometrial hyperplasia and/or carcinoma in women with estrogen-secreting tumors or polycystic ovarian disease. Later, observational studies and randomized, controlled trials suggested a relationship between unopposed estrogens and endometrial cancer and hyperplasia. The first, and to date only, effective... Climacteric journals http://www.medworm.com/rss/comments.php?id=2993081 Sun, 15 Nov 2009 11:30:31 +0100 2993081 http://www.medworm.com/index.php?rid=2993080&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905900%26dopt%3DAbstract Conclusion A patient's decision to accept or decline participation in the Stockholm trial was influenced by her objective risk of breast cancer recurrence and reflected her attitude to risk, uncertainty and preference to be active in treatment decisions. PMID: 19905900 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993080 Sun, 15 Nov 2009 11:30:28 +0100 2993080 http://www.medworm.com/index.php?rid=2993079&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905901%26dopt%3DAbstract Conclusions Our data suggested that the polymorphism XbaI may be strongly related to mammographic density. PMID: 19905901 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993079 Sun, 15 Nov 2009 11:30:25 +0100 2993079 http://www.medworm.com/index.php?rid=2993078&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905902%26dopt%3DAbstract CONCLUSION: ASAH1 is an estrogen-dependent member of the sphingolipid metabolism, which might provide further prognostic information in ER-positive breast cancers. PMID: 19905902 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993078 Sun, 15 Nov 2009 11:30:22 +0100 2993078 http://www.medworm.com/index.php?rid=2993077&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905903%26dopt%3DAbstract CONCLUSION: This study provides evidence that the risk of developing gynecological cancers with E/D use of several months to a few years is similar to the risks of developing gynecological cancer without HRT or use of other HRT. PMID: 19905903 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993077 Sun, 15 Nov 2009 11:30:20 +0100 2993077 http://www.medworm.com/index.php?rid=2993076&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905904%26dopt%3DAbstract CONCLUSION: Nearly three out of four women who had undergone bilateral oophorectomy were at risk of suffering HSDD; this risk was increased when less than 5 years since surgical menopause had elapsed. The use of hormone replacement therapy was associated with lower HSDD risk. PMID: 19905904 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993076 Sun, 15 Nov 2009 11:30:17 +0100 2993076 http://www.medworm.com/index.php?rid=2993075&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905905%26dopt%3DAbstract CONCLUSIONS: These data suggest that women experience significant vaginal dryness and low sexual desire and report a significant distress in the relationship with their partner after surgical menopause. Sexual counseling is mandatory in order to discuss potential therapeutic strategies, including testosterone use. PMID: 19905905 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993075 Sun, 15 Nov 2009 11:30:14 +0100 2993075 http://www.medworm.com/index.php?rid=2993074&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905906%26dopt%3DAbstract CONCLUSIONS: Women of climacteric age in Taiwan utilized TCM more often than other age groups. To deal with multiple symptoms and/or diseases among climacteric women, new prescription patterns of combining two or more herbal formulae have evolved. Studies on safety issues and drug-herb interactions are warranted for future research. PMID: 19905906 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993074 Sun, 15 Nov 2009 11:30:11 +0100 2993074 http://www.medworm.com/index.php?rid=2993073&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905907%26dopt%3DAbstract CONCLUSIONS: The menopausal symptoms in this study correspond to those in other studies on Asian women but the prevalence of typical and classical menopausal symptoms was lower compared to studies on Caucasian women. The perimenopausal women had the most significant decrease in quality of life, followed by postmenopausal women and premenopausal women. Vasomotor symptoms had a predominant influence on the quality of life. PMID: 19905907 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993073 Sun, 15 Nov 2009 11:30:08 +0100 2993073 http://www.medworm.com/index.php?rid=2993072&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19905991%26dopt%3DAbstract Conclusion Activity fostered by Wii Fit showed an immediate effect on balance and strength that needs confirmation by statistically powered studies. PMID: 19905991 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2993072 Thu, 12 Nov 2009 00:00:00 +0100 2993072 http://www.medworm.com/index.php?rid=2970822&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19886814%26dopt%3DAbstract Conclusions Insomnia in Japanese peri- and postmenopausal women correlates more strongly with depressed mood than with vasomotor symptoms. Cessation of smoking may improve the women's sleep quality, and hormone therapy and nightly hypnotics are both effective treatments. PMID: 19886814 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2970822 Tue, 03 Nov 2009 00:00:00 +0100 2970822 http://www.medworm.com/index.php?rid=2970821&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19886815%26dopt%3DAbstract Conclusion These results suggest that 8-week exercise training induces a decrease in visceral fat, and this reduction without weight loss does not change serum adiponectin levels and insulin sensitivity in ovariectomized rats. PMID: 19886815 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2970821 Tue, 03 Nov 2009 00:00:00 +0100 2970821 http://www.medworm.com/index.php?rid=2970820&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19886816%26dopt%3DAbstract Conclusion 'Early start' of estrogen-only hormone therapy was associated with reduced risk of global cognitive decline, and 'early start' estrogen-only and estrogen/progestogen hormone therapies showed increased risks of general memory decline. Even though this study did not have the power to discriminate between minor and mixed effects, it suggests that cognitive effects of hormone therapies may be mixed, depending on cognitive domain and timing of use/type of preparation. PMID: 19886816 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2970820 Tue, 03 Nov 2009 00:00:00 +0100 2970820 http://www.medworm.com/index.php?rid=2925190&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19848555%26dopt%3DAbstract Conclusions The effect of tibolone on body composition is favorable and therefore tibolone may be regarded as an alternative to continuous combined hormone therapy in postmenopausal women. PMID: 19848555 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2925190 Thu, 22 Oct 2009 00:00:00 +0100 2925190 http://www.medworm.com/index.php?rid=2903020&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19831723%26dopt%3DAbstract Authors: Canonico M, Scarabin PY Venous thromboembolism, either deep vein thrombosis or pulmonary embolism, is a serious side-effect of postmenopausal hormone therapy. Current use of oral estrogens increases the risk of venous thromboembolism, especially during the first year of treatment, but past users of hormone therapy have a similar risk as never-users. Among women at high risk for venous thromboembolism (for example, thrombogenic mutations, obesity), oral estrogens use further enhances the thrombotic risk. Recent studies have shown that transdermal estrogens might be safe with respect to thrombotic risk. The difference in thrombotic risk between oral and transdermal estrogens may be partially explained by changes in hemostasis. Few data are currently available regarding the impac... Climacteric journals http://www.medworm.com/rss/comments.php?id=2903020 Sun, 18 Oct 2009 17:12:03 +0100 2903020 http://www.medworm.com/index.php?rid=2899478&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811231%26dopt%3DAbstract Authors: Sturdee DW PMID: 19811231 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2899478 Fri, 16 Oct 2009 20:54:03 +0100 2899478 http://www.medworm.com/index.php?rid=2899477&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811232%26dopt%3DAbstract Authors: van der Schouw YT World-wide, cardiovascular disease is mainly seen as a male problem, whereas breast cancer is considered to be the most important chronic disease in women. However, cardiovascular disease is the largest single cause of death also in women, accounting for approximately one-third of the mortality, while breast cancer is responsible for less than 5% of the mortality. Physicians and women are equally unaware of these numbers. From a public health viewpoint, morbidity might be even more important, given the fact that therapeutic strategies have improved in the last decades, and disease fatality has been decreasing. In this contribution, the mortality and disability-adjusted life-years of cardiovascular disease world-wide will be summarized, and the relevance for p... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899477 Fri, 16 Oct 2009 20:54:03 +0100 2899477 http://www.medworm.com/index.php?rid=2899476&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811233%26dopt%3DAbstract Authors: Simoncini T Estrogen exerts pleiotropic functions on the cardiovascular system through binding to estrogen receptors (ERs). Traditionally, ERs have been recognized as transcription factors regulating the expression of target genes. In the past decades, however, numerous studies have revealed rapid actions of estrogen in different systems, especially in non-reproductive tissues such as the cardiovascular system. At this level, estrogen triggers rapid vasodilatation, exerts anti-inflammatory effects, regulates vascular cell growth and migration, and confers protection to cardiomyocytes. These so-called 'extranuclear actions' do not require gene expression or protein synthesis and are independent of the nuclear localization of ERs. Indeed, some of these actions are elicited by ER... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899476 Fri, 16 Oct 2009 20:54:03 +0100 2899476 http://www.medworm.com/index.php?rid=2899475&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811234%26dopt%3DAbstract Authors: Arnal JF, Laurell H, Fontaine C, Billon A, Calippe B, Lenfant F, Gourdy P Whereas hormonal therapy (HT) may increase the risk of coronary heart disease (CHD) and stroke in menopausal women, epidemiological studies (protection in premenopausal women) suggest and experimental studies (prevention of fatty streak development in animals) demonstrate a major atheroprotective action of estradiol (E2). The understanding of the deleterious and beneficial effects of estrogens is thus required at both a cellular and molecular level. Both the endothelium and the immuno-inflammatory system play a key role in the development of fatty streak deposit as well as in the rupture of the atherosclerotic plaque. Whereas E2 favors an anti-inflammatory effect in vitro (cultured cells), it rather elic... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899475 Fri, 16 Oct 2009 20:54:03 +0100 2899475 http://www.medworm.com/index.php?rid=2899474&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811235%26dopt%3DAbstract Authors: Mendelsohn ME This brief review summarizes the current state of the field for estrogen receptor actions in the cardiovascular system and the cardiovascular effects of hormone replacement therapy (HRT). It is organized into three parts: a short Introduction and overview of the current view of how estrogen works on blood vessels; a summary of the current status of clinical information regarding HRT and cardiovascular effects; and an update on state-of-the-art mouse models of estrogen action using estrogen receptor knockout mice. PMID: 19811235 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2899474 Fri, 16 Oct 2009 20:54:03 +0100 2899474 http://www.medworm.com/index.php?rid=2899473&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811236%26dopt%3DAbstract Authors: Carmina E Young women with polycystic ovary syndrome (PCOS) present a high risk for cardiovascular disease because of the presence of abdominal obesity, insulin resistance and androgen excess. In addition, they present with endothelial dysfunction and early signs of atherosclerosis (increased carotid intima-media thickness and increased coronary calcium). However, the evidence of increased cardiovascular events during the postmenopausal age is relatively small, although some recent studies have indicated a slight increase in the severity of cardiovascular disease in women who had PCOS during their fertile age. The discrepancy between cardiovascular risk in young age and postmenopausal cardiovascular events may depend on changes in the risk that happen during the late fertile a... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899473 Fri, 16 Oct 2009 20:54:03 +0100 2899473 http://www.medworm.com/index.php?rid=2899472&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811237%26dopt%3DAbstract Authors: Archer DF Premature menopause and bilateral oophorectomy in young women are associated with an increased incidence of cardiovascular disease, myocardial infarction and overall mortality. Observational studies suggest an interval of 5-10 years between loss of ovarian function and the increased risk of cardiovascular disease. This finding is consonant with a published autopsy study of women who had undergone bilateral oophorectomy. The progression of atherosclerosis is retarded with the use of estrogen replacement therapy in non-human primates and women. Hormone therapy reduced the incidence of cardiovascular disease in women following bilateral oophorectomy. These findings support the use of hormone therapy in young women who have lost ovarian function. PMID: 19811237 [PubM... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899472 Fri, 16 Oct 2009 20:54:03 +0100 2899472 http://www.medworm.com/index.php?rid=2899471&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811238%26dopt%3DAbstract Authors: Gambacciani M, Pepe A Climacteric complaints are the main indication for hormone replacement therapy (HRT) in the clinical practice. Observational studies demonstrating a protective effect of HRT on cardiovascular disease (CVD) were conducted in early menopausal, young, symptomatic women. Vasomotor symptoms correlate with lower level of plasma antioxidant activity, an increased cardiovascular reactivity to stressful situations, elevated cholesterol, higher sympathetic nerve activity, impaired flow-mediated dilation, hypertension and a higher risk of aortic calcification. All the available findings indicate that hot flushes can be seen as a marker for underlying vascular changes among mid-life, otherwise healthy, climacteric women. Thus, young, healthy symptomatic postmenopausa... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899471 Fri, 16 Oct 2009 20:54:03 +0100 2899471 http://www.medworm.com/index.php?rid=2899470&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811239%26dopt%3DAbstract Authors: Taddei S Together with the aging process, hypertension is the main risk factor contributing to the increase in cardiovascular morbidity and mortality in postmenopausal women, with a prevalence of around 60% in women older than 65 years. Considering that hypertension is a modifiable risk factor, the understanding of its epidemiology and pathophysiology and the development of appropriate therapeutic strategies are conceivably crucial in reducing cardiovascular risk. The high prevalence of hypertension in older women is largely due to the progressive stiffening of the arterial structure which accompanies the aging process in both sexes. However, the abrupt fall in circulating estrogen levels might independently contribute to the rise in blood pressure, through partly unknown mech... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899470 Fri, 16 Oct 2009 20:54:03 +0100 2899470 http://www.medworm.com/index.php?rid=2899469&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811240%26dopt%3DAbstract Authors: Rosano GM, Vitale C, Fini M Cardiovascular disease is the leading cause of death in postmenopausal women in Western countries. Despite preventive strategies, in the past decades, the incidence of cardiovascular events has shown a decline in men but a rise in women, matching the growth of the population of postmenopausal women. Several epidemiological findings suggest the causative role of ovarian hormone deficiency in the development of cardiovascular disease in women. Observational and randomized studies have suggested that initiation of hormone replacement therapy in early postmenopause could be beneficial from a cardiovascular point of view. Conversely, aging, time since menopause and presence of cardiovascular risk factors or cardiovascular disease may decrease its efficac... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899469 Fri, 16 Oct 2009 20:54:03 +0100 2899469 http://www.medworm.com/index.php?rid=2899468&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811241%26dopt%3DAbstract Authors: Bucciarelli P, Mannucci PM The process of aging is accompanied by several modifications in the hemostatic system at different levels (blood coagulation, fibrinolysis, platelet activity, vascular endothelium). These changes may explain the higher incidence of arterial and venous thrombosis in the elderly compared to young people. Genetic and environmental factors modulate in different combinations the expression of proteins involved in the hemostatic process. Among the latter, diet and smoking habits play an important role, as well as physical exercise and, for women, hormonal status. A gradual and progressive development of a low-grade inflammatory state (clearly demonstrated in the elderly) is also an important factor that influences hemostasis during aging. In spite of the f... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899468 Fri, 16 Oct 2009 20:54:03 +0100 2899468 http://www.medworm.com/index.php?rid=2899467&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811242%26dopt%3DAbstract Authors: Birkhäuser MH Quality of life may decrease after menopause. Hormone replacement therapy remains the first-line and most effective treatment for menopausal symptoms and improvement of low quality of life due to estrogen deficiency. The decrease of health-related quality of life in women suffering from cardiovascular disease may be superimposed on the decrease of quality of life induced by menopause itself. Postmenopausal women with acute cardiovascular disease have a significantly higher probability of death than men of the same age. Quality of life predicts long-term mortality. A myocardial infarction does not automatically interdict sexual activity. The Princeton guidelines classify patients suffering from cardiovascular diseases in three categories. Most patients belong... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899467 Fri, 16 Oct 2009 20:54:03 +0100 2899467 http://www.medworm.com/index.php?rid=2899466&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811243%26dopt%3DAbstract Authors: Mikkola TS The gynecologist is often the only physician a woman consults on a regular basis and therefore gynecologists play a crucial role in the primary prevention of cardiovascular disease. Cardiovascular risk factors in women entering the menopausal transition are poorly managed, partly due to the fact that primary-care physicians, gynecologists and cardiovascular physicians often fail to identify cardiovascular risk factors and also undertreat women at increased cardiovascular risk. Furthermore, most women are not well informed about their cardiovascular risk profile. Gynecologists and cardiologists should work together as a team in identifying and managing cardiovascular risk factors. European cardiologists and gynecologists have written a Consensus statement and a short... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899466 Fri, 16 Oct 2009 20:54:03 +0100 2899466 http://www.medworm.com/index.php?rid=2899465&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811244%26dopt%3DAbstract Authors: Pines A Diet and nutritional habits have a pivotal role in maintaining human health. Unhealthy eating, obesity and nutritional deficiencies may lead to various diseases. However, a most important component of lifestyle relates to physical activity. Sedentary people fare less well than those who exercise regularly. The benefits of exercise can be demonstrated in many bodily organs. The most frequently studied effect of exercise is reduction in cardiovascular morbidity and mortality, but positive effects on the musculoskeletal system, breast cancer risk, mood and cognition, and quality of life have been recorded as well. In many cases, a dose-response was evident, and even a mild to moderate degree of activity, performed only a few times weekly, may carry significant merits. The... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899465 Fri, 16 Oct 2009 20:54:03 +0100 2899465 http://www.medworm.com/index.php?rid=2899464&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811245%26dopt%3DAbstract Authors: Preston RA Menopause is commonly characterized by an increase in blood pressure. Higher blood pressure may partially explain the elevated risk for cardiovascular events observed in postmenopausal women. There is a graded relationship between blood pressure and cardiovascular risk which extends to levels of blood pressure well below 140/90 mmHg, the classical established blood pressure limit for the diagnosis of hypertension. Despite this knowledge and the wide availability of consensus treatment guidelines for hypertension, high blood pressure remains untreated or poorly treated in many postmenopausal patients. It is clear that novel and innovative population strategies for lowering blood pressure in postmenopausal women are warranted. Clinical trials suggest that oral estroge... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899464 Fri, 16 Oct 2009 20:54:03 +0100 2899464 http://www.medworm.com/index.php?rid=2899463&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811246%26dopt%3DAbstract Authors: Hodis HN, Mack WJ The discordance in coronary heart disease (CHD) outcome between randomized, controlled trials and observational studies of hormone replacement therapy (HRT) is likely the result of the dissimilar cohorts studied. This observation led to the formation of the timing hypothesis that benefits and risks of HRT depend upon age of HRT initiation and/or time of HRT initiation in relation to menopause. This hypothesis has been supported with data from large, randomized, controlled trials that have studied HRT and selective estrogen receptor modulators (SERMs) in the prevention of CHD. Initiation of HRT in women <60 years of age and/or within 10 years of menopause reduces both CHD and total mortality; SERMs have been shown to reduce CHD in women <60 years. What h... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899463 Fri, 16 Oct 2009 20:54:03 +0100 2899463 http://www.medworm.com/index.php?rid=2899462&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811247%26dopt%3DAbstract Authors: Canonico M, Scarabin PY Venous thromboembolism, either deep vein thrombosis or pulmonary embolism, is a serious side-effect of postmenopausal hormone therapy. Current use of oral estrogens increases the risk of venous thromboembolism, especially during the first year of treatment, but past users of hormone therapy have a similar risk as never-users. Among women at high risk for venous thromboembolism (for example, thrombogenic mutations, obesity), oral estrogens use further enhances the thrombotic risk. Recent studies have shown that transdermal estrogens might be safe with respect to thrombotic risk. The difference in thrombotic risk between oral and transdermal estrogens may be partially explained by changes in hemostasis. Few data are currently available regarding the impac... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899462 Fri, 16 Oct 2009 20:54:03 +0100 2899462 http://www.medworm.com/index.php?rid=2899461&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811248%26dopt%3DAbstract Authors: Lobo RA Stroke affects one in five women and is the third leading cause of death in the United States. The incidence increases with age, and the number of females experiencing a stroke is similar to the number of men, unlike in coronary disease, where the number of females suffering from the disease is lower before menopause and then slowly becomes equal to the number of men. There are multiple risk factors for stroke, but the most significant ones influencing the relationship between hormones and stroke are obesity, hypertension and smoking. There have been multiple studies looking at the relationship between hormones and stroke. Among observational studies, 21 have shown no effect, while six have shown a decreased risk and four studies, an increased risk. It is clear that th... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899461 Fri, 16 Oct 2009 20:54:03 +0100 2899461 http://www.medworm.com/index.php?rid=2899460&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811249%26dopt%3DAbstract Authors: Stevenson JC Hormone replacement therapy (HRT) can be administered orally and non-orally. Providing equivalent doses are given, all forms of HRT can equally relieve menopausal symptoms and prevent bone loss and osteoporosis. Different routes of administration will have differing metabolic effects, with oral HRT producing a hepatic first-pass effect not seen with non-oral HRT. The first-pass effect can produce benefits including larger reductions in low density lipoprotein cholesterol, lipoprotein(a) and insulin resistance, and larger increases in high density lipoprotein cholesterol. Unwanted effects are seen in increases in triglycerides and in coagulation activation. Cardiovascular effects of oral and transdermal HRT appear to be fairly similar, with improvements in vascular... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899460 Fri, 16 Oct 2009 20:54:03 +0100 2899460 http://www.medworm.com/index.php?rid=2899459&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811250%26dopt%3DAbstract Authors: Panay N One of the main concerns from the large secondary and primary prevention cardiovascular trials such as the Heart and Estrogen/progestin Replacement Study and the Women's Health Initiative (WHI) study was that there appeared to be an increased risk of coronary events in the first years of usage. These findings were initially surprising bearing in mind that observational trials had previously shown benefit. Subsequent analyses have confirmed that the risks were primarily in the over-seventies age group. In the younger age groups (50-59 years), there was a trend towards reduction of risk and a significant reduction in all-cause mortality. Why did this occur? There are a number of possible reasons but, in the opinion of the author, the dose of estrogen was the overriding f... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899459 Fri, 16 Oct 2009 20:54:03 +0100 2899459 http://www.medworm.com/index.php?rid=2899458&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811251%26dopt%3DAbstract Authors: Nath A, Sitruk-Ware R Following the publication of the Women's Health Initiative study, the controversy was raised regarding the role of progestins in hormonal replacement therapy (HRT). Some of the most prescribed molecules, with partial androgenic or glucocorticoid activity, have been shown to oppose partially the beneficial effect of estrogens on surrogate markers of cardiovascular disease risk. Unfortunately, this concern has been directed towards progestins as a class effect, although striking differences exist among the types of molecules used. The synthetic progestins used in HRT have varying pharmacologic properties depending on the molecules from which they are derived, either testosterone or progesterone. Very small structural changes in these molecules may induce co... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899458 Fri, 16 Oct 2009 20:54:03 +0100 2899458 http://www.medworm.com/index.php?rid=2899457&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811252%26dopt%3DAbstract Authors: Genazzani AR, Pluchino N Androgens play a primary role in female physiopathology. The age-related decline in the production of ovarian and adrenal androgens may significantly affect women's health. Scanty studies have been designed to establish whether androgen deficiency might directly affect cardiovascular biology and whether it might be a risk factor for cardiovascular disease in women during reproductive aging. The present short review examines the effect of androgen on the cardiovascular system, with particular regard to dehydroepiandrosterone and testosterone replacement in postmenopausal women. PMID: 19811252 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2899457 Fri, 16 Oct 2009 20:54:03 +0100 2899457 http://www.medworm.com/index.php?rid=2899456&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811253%26dopt%3DAbstract Authors: de Villiers TJ Selective estrogen receptor modulators (SERMs) have offered the promise of reducing the burden of coronary artery disease (CAD) in postmenopausal women, based on the positive effects recorded on intermediate markers (blood lipids and markers of inflammation). The effects of raloxifene, bazedoxifene and lasofoxifene on cardiovascular endpoint markers are presented as reported in recent, randomized, controlled trials. Raloxifene failed to significantly lower the risk of CAD in postmenopausal osteoporotic women, without any effect on stroke or early harm, but doubling the risk of venous thromboembolism. The risk of CAD was lowered in a subgroup of patients at risk of CAD. In a large randomized, controlled trial with CAD as the primary endpoint in patients at risk o... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899456 Fri, 16 Oct 2009 20:54:03 +0100 2899456 http://www.medworm.com/index.php?rid=2899455&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811254%26dopt%3DAbstract Authors: Nappi RE, Albani F, Chiovato L, Polatti F Urogenital aging and female sexual dysfunction (FSD) are significant problems following menopause. Estrogen decline is one of the key factors contributing to sexual functioning because of its crucial role for genital arousal (vasocongestion and lubrication) and other domains of the sexual response. Several common medical conditions, including cardiovascular disease (CVD), may interfere with women's sexual response across the aging process. FSD is one of the most common CVD-related quality-of-life complications with a major impact on patients' and their sexual partners' life. There is no evidence that FSD may represent an early indication of cardiovascular risk in postmenopausal women. In spite of the high prevalence, FSD remains largel... Climacteric journals http://www.medworm.com/rss/comments.php?id=2899455 Fri, 16 Oct 2009 20:54:03 +0100 2899455 http://www.medworm.com/index.php?rid=2880218&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811228%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 19811228 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2880218 Wed, 30 Sep 2009 23:00:00 +0100 2880218 http://www.medworm.com/index.php?rid=2880217&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811229%26dopt%3DAbstract Authors: PMID: 19811229 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2880217 Wed, 30 Sep 2009 23:00:00 +0100 2880217 http://www.medworm.com/index.php?rid=2880216&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19811230%26dopt%3DAbstract Authors: PMID: 19811230 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2880216 Wed, 30 Sep 2009 23:00:00 +0100 2880216 http://www.medworm.com/index.php?rid=2769163&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19731118%26dopt%3DAbstract Authors: Gharaibeh M, Al-Obeisat S, Hattab J Introduction Menopause is a transitional period that every woman goes through if she lives beyond the age of 52 years. The health care of women during this stage requires special attention to the identification of their health needs in order to provide competent care. The aim of the study was to assess severity of symptoms related to the menopausal period and to describe the differences in severity of menopausal symptoms according to menopausal status. Methods and design A descriptive cross-sectional design was used. Data were collected from 350 Jordanian women using a self-administered questionnaire consisting of a sociodemographic, medical and obstetrical history form and the Greene Climacteric Scale. Results Results on the severity of men... Climacteric journals http://www.medworm.com/rss/comments.php?id=2769163 Wed, 02 Sep 2009 23:00:00 +0100 2769163 http://www.medworm.com/index.php?rid=2769160&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19731121%26dopt%3DAbstract Conclusion Nearly three out of four women who had undergone bilateral oophorectomy were at risk of suffering HSDD; this risk was increased when less than 5 years since surgical menopause had elapsed. The use of hormone replacement therapy was associated with lower HSDD risk. PMID: 19731121 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2769160 Tue, 01 Sep 2009 23:00:00 +0100 2769160 http://www.medworm.com/index.php?rid=2769162&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19731119%26dopt%3DAbstract Conclusion Tibolone may be an alternative to conventional hormone replacement therapy in the treatment of climacteric symptoms and sexual dysfunction in postmenopausal women. PMID: 19731119 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2769162 Mon, 31 Aug 2009 23:00:00 +0100 2769162 http://www.medworm.com/index.php?rid=2769161&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19731120%26dopt%3DAbstract Conclusion This study provides evidence that the risk of developing gynecological cancers with E/D use of several months to a few years is similar to the risks of developing gynecological cancer without HRT or use of other HRT. PMID: 19731120 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2769161 Mon, 31 Aug 2009 23:00:00 +0100 2769161 http://www.medworm.com/index.php?rid=2769159&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19731122%26dopt%3DAbstract Conclusions In postmenopausal females, the cumulative exposure to endogenous estrogens, measured as years of menstruation, seems to be a significant protective factor against the development of postmenopausal osteoporosis. Age at menopause between 40 and 45 years, but not age at menarche, correlated with low bone mineral density in postmenopausal females. PMID: 19731122 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2769159 Mon, 31 Aug 2009 23:00:00 +0100 2769159 http://www.medworm.com/index.php?rid=2753172&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19722117%26dopt%3DAbstract Conclusions Our data do not support the existence of a single menopausal syndrome. There appears to be dialectic between culture and biology. It can be argued that symptoms experienced during the menopausal transition arise through a complexity of factors, not simply declining levels of estrogen or ethnicity; geographic location, local culture and temporality are factors that also need to be taken into account. PMID: 19722117 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2753172 Sun, 30 Aug 2009 23:00:00 +0100 2753172 http://www.medworm.com/index.php?rid=2753171&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19722118%26dopt%3DAbstract Conclusion A link has been demonstrated between the subjective and objective aspects of cognitive function in association with the menopausal transition. It is suggested that greater recognition be given to cognitive symptoms as forming part of the constellation of menopause-related symptoms. PMID: 19722118 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2753171 Sun, 30 Aug 2009 23:00:00 +0100 2753171 http://www.medworm.com/index.php?rid=2753173&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19718558%26dopt%3DAbstract Conclusions Women of climacteric age in Taiwan utilized TCM more often than other age groups. To deal with multiple symptoms and/or diseases among climacteric women, new prescription patterns of combining two or more herbal formulae have evolved. Studies on safety issues and drug-herb interactions are warranted for future research. PMID: 19718558 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2753173 Tue, 25 Aug 2009 23:00:00 +0100 2753173 http://www.medworm.com/index.php?rid=2700514&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19672733%26dopt%3DAbstract Conclusion Data obtained in this study suggest that HRT is not only effective for treating menopausal complaints but also increases cardiovascular performance by improving especially diastolic functions in early postmenopausal women. PMID: 19672733 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2700514 Mon, 10 Aug 2009 23:00:00 +0100 2700514 http://www.medworm.com/index.php?rid=2679149&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657786%26dopt%3DAbstract Conclusions These data suggest that women experience significant vaginal dryness and low sexual desire and report a significant distress in the relationship with their partner after surgical menopause. Sexual counseling is mandatory in order to discuss potential therapeutic strategies, including testosterone use. PMID: 19657786 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2679149 Mon, 03 Aug 2009 23:00:00 +0100 2679149 http://www.medworm.com/index.php?rid=2679145&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657790%26dopt%3DAbstract Conclusion There is no protective effect of a previous exercise-training state on ovariectomy-induced liver and adipocyte fat accumulation if rats remain sedentary after ovariectomy. However, training conducted concurrently with estrogen withdrawal has protective effects, especially on liver fat accumulation, whether or not rats were previously trained. PMID: 19657790 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2679145 Sun, 02 Aug 2009 23:00:00 +0100 2679145 http://www.medworm.com/index.php?rid=2679143&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657792%26dopt%3DAbstract Conclusions There were no changes in liver function after a 9-month treatment with transdermal estradiol plus norethisterone in symptomatic postmenopausal patients with hepatitis C. PMID: 19657792 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2679143 Sun, 02 Aug 2009 23:00:00 +0100 2679143 http://www.medworm.com/index.php?rid=2679148&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657787%26dopt%3DAbstract We report a case of coagulation activation, fluid retention and transient autoimmune hepatitis most likely triggered by the use of black cohosh. Diagnostic procedures aimed to explain lower leg edema are not uncommon in the age group of women suffering from climacteric and menopausal symptoms. Therefore, black cohosh-induced fluid retention and coagulation activation should be considered in differential diagnosis, especially if thrombosis has been excluded. PMID: 19657787 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2679148 Thu, 30 Jul 2009 23:00:00 +0100 2679148 http://www.medworm.com/index.php?rid=2679147&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657788%26dopt%3DAbstract Conclusions RHI varies widely in healthy women within the first 3 years of menopause. RHI was not associated with standard risk assessment algorithms, CAC or CIMT. RHI may indicate an additional, independent component and non-invasive tool to further stratify cardiovascular risk in recently menopausal women. As KEEPS continues, data on RHI will provide information regarding hormonal therapy, endovascular biology and atherosclerotic risk. PMID: 19657788 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2679147 Thu, 30 Jul 2009 23:00:00 +0100 2679147 http://www.medworm.com/index.php?rid=2679146&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657789%26dopt%3DAbstract Conclusion ASAH1 is an estrogen-dependent member of the sphingolipid metabolism, which might provide further prognostic information in ER-positive breast cancers. PMID: 19657789 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2679146 Thu, 30 Jul 2009 23:00:00 +0100 2679146 http://www.medworm.com/index.php?rid=2679144&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657791%26dopt%3DAbstract Conclusions Our data suggested that the polymorphism XbaI may be strongly related to mammographic density. PMID: 19657791 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2679144 Thu, 30 Jul 2009 23:00:00 +0100 2679144 http://www.medworm.com/index.php?rid=2679142&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657793%26dopt%3DAbstract This article reviews publications dating back more than a century describing investigations of the endometrium, including those examining the relationship between endometrial hyperplasia and carcinoma, the influence of estrogens on the endometrium, and strategies for protecting the endometrium from unopposed estrogen stimulation. Endometrial hyperplasia and carcinoma studies date from before 1900. The influence of endogenous estrogens on the endometrium became evident with observations of endometrial hyperplasia and/or carcinoma in women with estrogen-secreting tumors or polycystic ovarian disease. Later, observational studies and randomized, controlled trials suggested a relationship between unopposed estrogens and endometrial cancer and hyperplasia. The first, and to date only, effective... Climacteric journals http://www.medworm.com/rss/comments.php?id=2679142 Thu, 30 Jul 2009 23:00:00 +0100 2679142 http://www.medworm.com/index.php?rid=2654816&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19639481%26dopt%3DAbstract Conclusions In postmenopausal women, breast arterial calcification may represent a higher likelihood of cardiovascular disease. PMID: 19639481 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2654816 Mon, 27 Jul 2009 23:00:00 +0100 2654816 http://www.medworm.com/index.php?rid=2649362&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19637056%26dopt%3DAbstract Conclusion These data are reassuring that, even in women exposed to very high doses of estrogen for a prolonged period of time, hyperprolactinemia is unlikely to occur. PMID: 19637056 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2649362 Mon, 20 Jul 2009 23:00:00 +0100 2649362 http://www.medworm.com/index.php?rid=2638316&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19626495%26dopt%3DAbstract Conclusions The menopausal symptoms in this study correspond to those in other studies on Asian women but the prevalence of typical and classical menopausal symptoms was lower compared to studies on Caucasian women. The perimenopausal women had the most significant decrease in quality of life, followed by postmenopausal women and premenopausal women. Vasomotor symptoms had a predominant influence on the quality of life. PMID: 19626495 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2638316 Wed, 15 Jul 2009 23:00:00 +0100 2638316 http://www.medworm.com/index.php?rid=2593377&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19591006%26dopt%3DAbstract Conclusion The prevalence of premalignant and malignant endometrial polyps is very low. Advanced age, menopause, obesity and diabetes increase the risk of endometrial polyp malignancy. PMID: 19591006 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2593377 Tue, 07 Jul 2009 23:00:00 +0100 2593377 http://www.medworm.com/index.php?rid=2593376&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19591007%26dopt%3DAbstract Conclusion Transdermal estrogen treatment has a protective effect against the risk factors of metabolic syndrome (homocysteine, ADMA, HDL cholesterol) in surgically menopausal patients who have undergone surgery in the early premenopausal period. PMID: 19591007 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2593376 Tue, 07 Jul 2009 23:00:00 +0100 2593376 http://www.medworm.com/index.php?rid=2593375&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19591008%26dopt%3DAbstract Authors: Holroyd CR, Edwards CJ Autoimmune diseases are generally more common in women than men; however, there is no simple explanation for this. Sex hormones, especially estrogen (but also prolactin and testosterone), play important roles in these diseases. Estrogens are generally considered to enhance autoimmunity and have multiple effects on the immune system through various cell types and molecular pathways. There is much evidence supporting the role of estrogen in the pathogenesis of systemic lupus erythematosus (SLE): the disease occurs much more frequently in women, especially during the years of child-bearing potential, and commonly flares during pregnancy. The relationship between estrogen and the development of SLE is complex, however. Exogenous estrogens have been historica... Climacteric journals http://www.medworm.com/rss/comments.php?id=2593375 Mon, 06 Jul 2009 23:00:00 +0100 2593375 http://www.medworm.com/index.php?rid=2593374&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19591009%26dopt%3DAbstract Conclusion A patient's decision to accept or decline participation in the Stockholm trial was influenced by her objective risk of breast cancer recurrence and reflected her attitude to risk, uncertainty and preference to be active in treatment decisions. PMID: 19591009 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2593374 Mon, 06 Jul 2009 23:00:00 +0100 2593374 http://www.medworm.com/index.php?rid=2593373&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19591010%26dopt%3DAbstract Conclusion This study showed that E(2), at both 1.0 mg and 0.5 mg doses, was effective in increasing bone mineral density with an acceptable safety and tolerability profile in Japanese postmenopausal women with osteoporosis but that the bone mineral density response was higher with the 1.0 mg dose. PMID: 19591010 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2593373 Mon, 06 Jul 2009 23:00:00 +0100 2593373 http://www.medworm.com/index.php?rid=2561750&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19565370%26dopt%3DAbstract Conclusion The study provides evidence that estradiol/dydrogesterone use of several months to a few years is not associated with a higher risk of cardiovascular events than use of other HRT. PMID: 19565370 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2561750 Thu, 25 Jun 2009 23:00:00 +0100 2561750 http://www.medworm.com/index.php?rid=2533563&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19387881%26dopt%3DAbstract CONCLUSIONS: Although hormone therapy appears to suspend breast involution, it does not increase breast density in the majority of treated women. Progestins differing in pharmacological properties may have a variable impact on breast density. PMID: 19387881 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533563 Sun, 31 May 2009 23:00:00 +0100 2533563 http://www.medworm.com/index.php?rid=2533562&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19387882%26dopt%3DAbstract CONCLUSIONS: Increased numbers of subpopulations of EPCs in normal postmenopausal women might contribute to the gender-specific difference of CAD in middle age. Lack of difference in EPCs between women and men with CAD suggests that stem cells become unable to play a protective role when the disease is clinically evident. PMID: 19387882 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533562 Sun, 31 May 2009 23:00:00 +0100 2533562 http://www.medworm.com/index.php?rid=2533561&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19387883%26dopt%3DAbstract Authors: Nath A, Sitruk-Ware R Compounds that can be described as selective estrogen receptor modulators (SERMs) have expanded dramatically over the past two decades. The ability of SERMs to act as estrogens in certain tissues while remaining inert or acting as an anti-estrogen in other tissues has opened up opportunities for treating specific estrogen-modulated diseases without accepting the risk of systemic estrogen activity. SERM development has resulted in significant therapeutic advances for breast cancer, osteoporosis and potentially other diseases associated with the menopause. After the publication of the Women's Health Initiative, interest in compound selectivity that reduces menopausal symptoms while protecting bone, breast, uterus and the heart has increased. Future SERMs ma... Climacteric journals http://www.medworm.com/rss/comments.php?id=2533561 Sun, 31 May 2009 23:00:00 +0100 2533561 http://www.medworm.com/index.php?rid=2533560&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19387884%26dopt%3DAbstract CONCLUSION: Our study suggests that the effect of E2/NETA regimens on mammographic density could be at least as detrimental to the breast tissue as several other estrogen + progestin regimens. Our results suggest that both low- and high-dose E2/NETA influence mammographic density, but there were some indications in our analyses that the effect of low-dose E2/NETA could be slightly lower than that of the older high-dose regimen. PMID: 19387884 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533560 Sun, 31 May 2009 23:00:00 +0100 2533560 http://www.medworm.com/index.php?rid=2533550&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19437195%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 19437195 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533550 Sun, 31 May 2009 23:00:00 +0100 2533550 http://www.medworm.com/index.php?rid=2533549&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19437196%26dopt%3DAbstract Authors: Studd J A case is made for estrogens to be the first-choice therapy for the prevention and treatment of osteoporosis in women below the age of 60 years. Estrogens produce a dose-related increase in bone density and also, by their effect on collagen, have a beneficial effect not only on the bone matrix but the intravertebral disc. Bisphosphonates do not have that effect upon the disc. Estrogens are also associated with other beneficial effects upon mood, vasomotor symptoms, pelvic atrophy, sexuality and quality of life. The data from the Women's Health Initiative (WHI) study are used as a justification for not using estrogens but the neglect of estrogen therapy by physicians antedated this and other studies by many years. Subsequent publications from the WHI study show that hor... Climacteric journals http://www.medworm.com/rss/comments.php?id=2533549 Sun, 31 May 2009 23:00:00 +0100 2533549 http://www.medworm.com/index.php?rid=2533548&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19437197%26dopt%3DAbstract Authors: de Villiers TJ PMID: 19437197 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533548 Sun, 31 May 2009 23:00:00 +0100 2533548 http://www.medworm.com/index.php?rid=2533547&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19437198%26dopt%3DAbstract CONCLUSIONS: We found that it is not only women with high pain intensity and disability who experience reduced well-being, but also those with low levels of pain and disability. Longitudinal investigation is needed to investigate the predictive nature of both low and high levels of pain and disability in determining poor well-being in community-based women. PMID: 19437198 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533547 Sun, 31 May 2009 23:00:00 +0100 2533547 http://www.medworm.com/index.php?rid=2533546&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19479488%26dopt%3DAbstract Conclusions Risk-reducing bilateral salpingo-oophorectomy as compared to natural menopause is associated with more severe climacteric symptoms. However, the procedure does not interfere with the overall perceived quality of life and improves the perception of cancer risk. PMID: 19479488 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533546 Sun, 24 May 2009 23:00:00 +0100 2533546 http://www.medworm.com/index.php?rid=2533545&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19479489%26dopt%3DAbstract Conclusions In Asian women, micro-dose estradiol was significantly superior to placebo in improving vasomotor symptoms. The bleeding profile was comparable with that of placebo. Micro-dose estradiol was safe and well tolerated in Asian women. PMID: 19479489 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533545 Sun, 24 May 2009 23:00:00 +0100 2533545 http://www.medworm.com/index.php?rid=2533553&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19437194%26dopt%3DAbstract Conclusions Substantial declines in HT user prevalence as well as changes in HT use patterns to lower-dose estrogen preparations and non-oral routes of administration are likely to reflect effects of the publication of the WHI results. Consulting a gynecologist appeared to be relevant for a woman's decision to continue HT. PMID: 19437194 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533553 Sun, 10 May 2009 23:00:00 +0100 2533553 http://www.medworm.com/index.php?rid=2533554&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19421917%26dopt%3DAbstract Conclusions Our study suggests that the scale is appropriate for use for Hispanic and White non-Hispanic women and is capable of detecting differences among women with different menopause-related symptoms. Menopause-related symptoms measured by the scale were correlated with global quality of life. PMID: 19421917 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533554 Tue, 05 May 2009 23:00:00 +0100 2533554 http://www.medworm.com/index.php?rid=2533559&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19415539%26dopt%3DAbstract Conclusion Metabolic syndrome was highly prevalent among Brazilian postmenopausal women seeking gynecologic health care. Abdominal obesity, diabetes, hypertension and high CRP were strong MetS predictors and hormone therapy appeared to play a protective role for this condition. PMID: 19415539 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533559 Fri, 01 May 2009 23:00:00 +0100 2533559 http://www.medworm.com/index.php?rid=2533558&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19415540%26dopt%3DAbstract Conclusion Gabapentin appears to be effective for the treatment of hot flushes with a favorable effect on quality of sleep. Vitamin E has only marginal effect on vasomotor symptoms. PMID: 19415540 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533558 Fri, 01 May 2009 23:00:00 +0100 2533558 http://www.medworm.com/index.php?rid=2533557&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19415541%26dopt%3DAbstract Conclusion These findings suggest that initiation of ET around the time of menopause may modulate age-related differences in regional gray matter concentration. The functional significance of our findings remains unknown. PMID: 19415541 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533557 Fri, 01 May 2009 23:00:00 +0100 2533557 http://www.medworm.com/index.php?rid=2533556&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19415542%26dopt%3DAbstract Conclusions In this cohort, both prevalence of use and reasons for initiating MHT have varied between 2001 and 2003, while the modalities of use remained essentially the same. PMID: 19415542 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533556 Fri, 01 May 2009 23:00:00 +0100 2533556 http://www.medworm.com/index.php?rid=2533555&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19415543%26dopt%3DAbstract Conclusion The control of bone formation offers new clinical potential. Stimulation of bone formation by PTH has translated into fracture protection. The action of strontium ranelate has been claimed to be mediated by some level of bone formation, but this hypothesis still needs clarification. PMID: 19415543 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533555 Fri, 01 May 2009 23:00:00 +0100 2533555 http://www.medworm.com/index.php?rid=2533565&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19387879%26dopt%3DAbstract Conclusion In this specific climacteric population, depressive symptoms were very prevalent and were associated with the severity of menopausal symptoms (somatic and psychological) and partner's problems. PMID: 19387879 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2533565 Tue, 21 Apr 2009 23:00:00 +0100 2533565 http://www.medworm.com/index.php?rid=2533564&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19387880%26dopt%3DAbstract Authors: Calleja-Agius J, Brincat MP The major cause of urogenital atrophy in menopausal women is estrogen loss. The symptoms are usually progressive in nature and deteriorate with time from the menopausal transition. The most prevalent urogenital symptoms are vaginal dryness, vaginal irritation and itching. The classical changes in an atrophic vulva include loss of labial and vulvar fullness, with narrowing of the introitus and inflamed mucosal surfaces. Dyspareunia and vaginal bleeding from fragile atrophic skin are common problems. Other urogenital complaints include frequency, nocturia, urgency, incontinence and urinary tract infections. Atrophic changes of the vulva, vagina and lower urinary tract can have a large impact on the quality of life of the menopausal woman. However, hor... Climacteric journals http://www.medworm.com/rss/comments.php?id=2533564 Tue, 21 Apr 2009 23:00:00 +0100 2533564 http://www.medworm.com/index.php?rid=2309293&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19340614%26dopt%3DAbstract Conclusion PGRMC1 is expressed in breast cancer tissue and mediates an RU-486-independent proliferative signal. It might also contribute to VEGF-induced neovascularization in tumor tissue. Thus, screening for PGRMC1 expression might be of interest to identify women with a higher expression of PGRMC1 and who might thus be susceptible for breast cancer development under hormone replacement therapy. H. Neubauer and G. Adam contributed equally to this manuscript. PMID: 19340614 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2309293 Wed, 01 Apr 2009 04:00:00 +0100 2309293 http://www.medworm.com/index.php?rid=2237838&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19259852%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 19259852 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2237838 Fri, 06 Mar 2009 13:29:45 +0100 2237838 http://www.medworm.com/index.php?rid=2237837&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19259853%26dopt%3DAbstract Authors: Quinn SD, Domoney C It has been established that the lower urinary tract is sensitive to the effects of estrogen, sharing a common embryological origin with the female genital tract, the urogenital sinus. Urge urinary incontinence is more prevalent after the menopause, and the peak prevalence of stress incontinence occurs around the time of the menopause. Many studies, however, indicate that the prevalence of stress incontinence falls after the menopause. Until recently, estrogen, usually as part of a hormone replacement therapy (HRT) regimen, was used for treatment of urinary incontinence in postmenopausal women. Although its use in the treatment of vaginal atrophy is well established, the effect of HRT on urinary continence is controversial. A number of randomized, placebo-c... Climacteric journals http://www.medworm.com/rss/comments.php?id=2237837 Fri, 06 Mar 2009 13:29:34 +0100 2237837 http://www.medworm.com/index.php?rid=2237836&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19259854%26dopt%3DAbstract Conclusions There has been a continuing decline in both the overall prevalence and length of use of conventional HT from 2003, probably in association with negative media about HT. Of medical concern is that about one-quarter of women using HT around menopause now chooses unregistered hormonal mixtures that are untested for long-term safety and efficacy. PMID: 19259854 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2237836 Fri, 06 Mar 2009 13:29:15 +0100 2237836 http://www.medworm.com/index.php?rid=2070464&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19116802%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 19116802 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2070464 Fri, 02 Jan 2009 05:25:29 +0100 2070464 http://www.medworm.com/index.php?rid=2070463&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19116803%26dopt%3DAbstract Conclusion Sham-controlled RCTs fail to show specific effects of acupuncture for control of menopausal hot flushes. More rigorous research seems warranted. PMID: 19116803 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2070463 Fri, 02 Jan 2009 05:25:25 +0100 2070463 http://www.medworm.com/index.php?rid=2070462&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19116804%26dopt%3DAbstract Authors: PMID: 19116804 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2070462 Fri, 02 Jan 2009 05:25:22 +0100 2070462 http://www.medworm.com/index.php?rid=2064225&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19105055%26dopt%3DAbstract Conclusion Our results suggest that menopause-related insulin resistance, obesity and ethanol ingestion as well as menopause may contribute to an increase in level of serum urate in postmenopausal Japanese women. PMID: 19105055 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2064225 Mon, 22 Dec 2008 05:00:00 +0100 2064225 http://www.medworm.com/index.php?rid=2044630&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19085562%26dopt%3DAbstract Conclusions Our results demonstrated a significant association between the psychosocial work environment and women's cardiovascular health at menopause. Job strain was a significant contributor to an atherogenic lipid profile, whereas work control predicted a favorable profile. Hence, the argument is now compelling that psychosocial factors should be included in the risk profiles for cardiovascular disease in women. PMID: 19085562 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2044630 Thu, 11 Dec 2008 05:00:00 +0100 2044630 http://www.medworm.com/index.php?rid=2024733&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19065308%26dopt%3DAbstract Conclusions These results challenge assumptions about migrated Asian populations living in western cultures and the qualitative data provides information that might increase understanding of the experience and meanings of menopause amongst migrated Asian communities. PMID: 19065308 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2024733 Mon, 08 Dec 2008 05:00:00 +0100 2024733 http://www.medworm.com/index.php?rid=2024732&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19065309%26dopt%3DAbstract Conclusions Efforts should be made to provide education about the menopause to all women in their respective communities, especially to those who are approaching their fifth decade and who have no formal education, to better prepare them for this change of life. PMID: 19065309 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2024732 Mon, 08 Dec 2008 05:00:00 +0100 2024732 http://www.medworm.com/index.php?rid=2024734&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19061056%26dopt%3DAbstract Authors: Andrikoula M, Prelevic G Vasomotor symptoms are generally recognized as one of the most common symptoms, or signs, of the menopause, together with menstrual cycle changes. The etiology of hot flushes is unknown, although several mechanisms have been implicated. The reduction in hot flushes with estrogen replacement therapy suggests a hormonal etiology. However, the levels of estrogens do not appear to correlate with hot flushes. It seems more likely that the rate of change of plasma estrogen concentrations influences the thermoregulatory system via the hypothalamus. During the past few decades, remedies for the treatment of hot flushes have advanced from simple sedatives and purgatives to the use of ovarian extracts and, finally, to pharmacological estrogen preparations. In vi... Climacteric journals http://www.medworm.com/rss/comments.php?id=2024734 Fri, 05 Dec 2008 05:00:00 +0100 2024734 http://www.medworm.com/index.php?rid=2015330&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19058059%26dopt%3DAbstract Conclusions These results indicate that cigarette smoking may reduce the efficacy of nasal estradiol to increase bone mass in early postmenopausal women. In addition, smoking may increase spontaneous bone loss in untreated women. PMID: 19058059 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2015330 Thu, 04 Dec 2008 05:00:00 +0100 2015330 http://www.medworm.com/index.php?rid=2015329&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19058060%26dopt%3DAbstract Conclusion These results provide evidence that this physiotherapist-designed program preserves/reverses the balance decline associated with age and leads to adoption of a more active lifestyle. PMID: 19058060 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2015329 Thu, 04 Dec 2008 05:00:00 +0100 2015329 http://www.medworm.com/index.php?rid=2012767&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19051075%26dopt%3DAbstract Conclusion These results suggest that, with declines in endogenous estrogen at menopause, numbers of procoagulant microparticles increase and thus may provide a means to explore mechanisms for cardiovascular risk development in newly menopausal women. PMID: 19051075 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2012767 Tue, 02 Dec 2008 05:00:00 +0100 2012767 http://www.medworm.com/index.php?rid=2012766&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19051101%26dopt%3DAbstract Conclusion The knowledge of Bahraini women about menopause and HT is average. Lack of knowledge was greatest in areas related to heart disease. Better education about menopause needs to be achieved regarding the long-term risk associated with menopause and the pros and cons of HT. PMID: 19051101 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=2012766 Tue, 02 Dec 2008 05:00:00 +0100 2012766 http://www.medworm.com/index.php?rid=1978726&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19021018%26dopt%3DAbstract Conclusion These results indicate that a resistance training program could be useful in preventing body weight as well as adipose tissue and liver fat regain in Ovx rats, following diet-induced weight loss. It is suggested that changing from a food restriction regimen to a resistance training program can be an interesting strategy to promote successful long-term weight reduction in postmenopausal women. PMID: 19021018 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1978726 Wed, 19 Nov 2008 05:00:00 +0100 1978726 http://www.medworm.com/index.php?rid=1954310&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991072%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 18991072 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1954310 Thu, 13 Nov 2008 08:29:09 +0100 1954310 http://www.medworm.com/index.php?rid=1950282&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991072%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 18991072 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950282 Wed, 12 Nov 2008 08:58:18 +0100 1950282 http://www.medworm.com/index.php?rid=1950281&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991073%26dopt%3DAbstract Authors: Pines A PMID: 18991073 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950281 Wed, 12 Nov 2008 08:58:18 +0100 1950281 http://www.medworm.com/index.php?rid=1950280&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991074%26dopt%3DAbstract Conclusions Sociodemographic features may contribute to MS. Hence, prevention of MS should encompass sociodemographic features. PMID: 18991074 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950280 Wed, 12 Nov 2008 08:58:18 +0100 1950280 http://www.medworm.com/index.php?rid=1950279&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991075%26dopt%3DAbstract Conclusion Raloxifene administered to castrated female rats for 30 days increased the distal urethral epithelial thickness and did not alter the weight of the urethra. PMID: 18991075 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950279 Wed, 12 Nov 2008 08:58:18 +0100 1950279 http://www.medworm.com/index.php?rid=1950278&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991076%26dopt%3DAbstract Conclusions CEE/MPA and tibolone have comparable effects on most metabolic risk factors investigated. The effect of tibolone on fibrinolysis and triglycerides suggests that tibolone has a favorable pharmacological profile on these risk factors when compared to CEE/MPA. PMID: 18991076 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950278 Wed, 12 Nov 2008 08:58:18 +0100 1950278 http://www.medworm.com/index.php?rid=1950277&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991077%26dopt%3DAbstract Conclusions The oral low dose of unopposed estradiol therapy had a favorable effect on glycoinsulinemic metabolism in healthy postmenopausal women; however, the standard dose caused a slight but significant deterioration in insulin sensitivity. PMID: 18991077 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950277 Wed, 12 Nov 2008 08:58:18 +0100 1950277 http://www.medworm.com/index.php?rid=1950276&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991078%26dopt%3DAbstract Conclusions An increment in the androgenic milieu that correlates with abdominal fat, insulin resistance and atherogenic lipoproteins becomes evident after the menopausal transition and suggests that evaluation of cardiovascular disease risk in these women should include androgens, considering that abdominal obesity is one of the main determinants of the relationship between androgenic parameters and cardiovascular risk factors. PMID: 18991078 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950276 Wed, 12 Nov 2008 08:58:18 +0100 1950276 http://www.medworm.com/index.php?rid=1950275&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991079%26dopt%3DAbstract Conclusion A large proportion of women complaining of vasomotor complaints took self-care actions and the choice of self-care actions depended on the area of residence and educational level. The use of modern remedies and less of the traditional remedies was more common amongst the more affluent and educated women than women in rural areas who either did nothing or resorted to the more simple type of self-care actions. Contrary to our expectations, the use of traditional remedies was low. PMID: 18991079 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950275 Wed, 12 Nov 2008 08:58:18 +0100 1950275 http://www.medworm.com/index.php?rid=1950274&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991080%26dopt%3DAbstract Conclusions These three cases of postmenopausal endometriosis support the celomic metaplasia theory for the genesis of this disease. PMID: 18991080 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950274 Wed, 12 Nov 2008 08:58:18 +0100 1950274 http://www.medworm.com/index.php?rid=1950273&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18991081%26dopt%3DAbstract Authors: PMID: 18991081 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1950273 Wed, 12 Nov 2008 08:58:18 +0100 1950273 http://www.medworm.com/index.php?rid=1932482&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18979300%26dopt%3DAbstract Conclusions The new progestogen drospirenone seems to have favorable effects on the cardiovascular system due to its antimineralocorticoid property. Clinical studies must prove the results of this in vitro experiment. PMID: 18979300 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1932482 Fri, 31 Oct 2008 04:00:00 +0100 1932482 http://www.medworm.com/index.php?rid=1805073&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18795466%26dopt%3DAbstract Can we analyze the data more clearly by employing a different approach to estimate hot flushes? Climacteric. 2008 Oct;11(5):439-40 Authors: Kim KH, Lee MS, Choi SM PMID: 18795466 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1805073 Fri, 19 Sep 2008 07:58:46 +0100 1805073 http://www.medworm.com/index.php?rid=1796717&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781478%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 18781478 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796717 Wed, 17 Sep 2008 08:01:06 +0100 1796717 http://www.medworm.com/index.php?rid=1796716&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781479%26dopt%3DAbstract CONCLUSIONS: It is likely that the WHI studies were biased and that they overestimated the overall and time- and duration-specific risks of VTE, myocardial infarction and stroke. Particularly for myocardial infarction, a protective effect, perhaps strongest among the youngest women, but present at all ages, may correctly have been identified in earlier observational studies, and have been missed in the WHI studies. This paper was presented by Professor Shapiro as a Plenary Lecture at the 12th World Congress on Menopause, Madrid, May 2008. PMID: 18781479 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796716 Wed, 17 Sep 2008 08:01:02 +0100 1796716 http://www.medworm.com/index.php?rid=1796715&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781480%26dopt%3DAbstract CONCLUSION: These data show that circulating CGRP levels are influenced by menopausal status and suggest additional mechanisms through which increased risk of hyperinsulinemia and cardiovascular disease may arise in postmenopausal women. PMID: 18781480 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796715 Wed, 17 Sep 2008 08:00:59 +0100 1796715 http://www.medworm.com/index.php?rid=1796714&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781481%26dopt%3DAbstract CONCLUSIONS: The combination of coffee consumption and HRT could lower insulin resistance in postmenopausal women. In overweight women, greater insulin sensitivity is associated with intake of espresso coffee and not with HRT; in normal weight women, only HRT is associated with lower insulin resistance. PMID: 18781481 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796714 Wed, 17 Sep 2008 08:00:56 +0100 1796714 http://www.medworm.com/index.php?rid=1796713&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781482%26dopt%3DAbstract CONCLUSIONS: Present results show that, in healthy postmenopausal women, endothelium-dependent vasodilatation is related to BMI, arteries of slender women dilating less than those of their heavier counterparts. A low BMI does not appear to be beneficial for artery vasodilatation in healthy postmenopausal women. PMID: 18781482 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796713 Wed, 17 Sep 2008 08:00:53 +0100 1796713 http://www.medworm.com/index.php?rid=1796712&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781483%26dopt%3DAbstract CONCLUSIONS: Conjugated equine estrogen and raloxifene do not seem to affect arterial stiffness of healthy normotensive women less than 10 years since menopause. Reduction in arterial stiffness seems related to its basal level. PMID: 18781483 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796712 Wed, 17 Sep 2008 08:00:50 +0100 1796712 http://www.medworm.com/index.php?rid=1796711&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781484%26dopt%3DAbstract CONCLUSIONS: In this study, there was no consistent pattern of MHPG increase or decrease in the women experiencing hot flushes. PMID: 18781484 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796711 Wed, 17 Sep 2008 08:00:48 +0100 1796711 http://www.medworm.com/index.php?rid=1796710&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781485%26dopt%3DAbstract CONCLUSION: The results of this study suggest that the CYP17 MspAI polymorphism was not significantly associated with an increased risk of reporting hot flushes. PMID: 18781485 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796710 Wed, 17 Sep 2008 08:00:44 +0100 1796710 http://www.medworm.com/index.php?rid=1796709&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781486%26dopt%3DAbstract CONCLUSIONS: Soy modified the concentrations of estrone, testosterone and some endothelial markers. Equol production enforced these effects. Soy supplementation may be clinically significant in tibolone users. PMID: 18781486 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796709 Wed, 17 Sep 2008 08:00:41 +0100 1796709 http://www.medworm.com/index.php?rid=1796708&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18781487%26dopt%3DAbstract CONCLUSIONS: Characterization of the anatomical changes and relationships of external genitalia in postmenopausal women is important for functional and perioperative evaluation. In addition to reconstructive surgical procedures, determination of the objective measurements of anatomical landmarks in postmenopausal external genitalia might also be useful for assessing the results of treatment of 'atrophic' changes in women. PMID: 18781487 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=1796708 Wed, 17 Sep 2008 08:00:36 +0100 1796708