MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Climacteric' source. Wed, 08 Feb 2012 16:54:22 +0100 http://www.medworm.com/index.php?rid=5580189&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22224864%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 22224864 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5580189 Fri, 13 Jan 2012 04:54:13 +0100 5580189 http://www.medworm.com/index.php?rid=5552859&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22201242%26dopt%3DAbstract Authors: Pines A PMID: 22201242 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5552859 Sat, 31 Dec 2011 11:13:33 +0100 5552859 http://www.medworm.com/index.php?rid=5552857&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22206414%26dopt%3DAbstract Conclusion Women in the climacteric stage require more information about their physical, psychological and social needs, as well as the potential impact on their health during old age. Empowerment during the climacteric can contribute to improving the perception about this stage as well as the importance of self-care. PMID: 22206414 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5552857 Thu, 29 Dec 2011 05:00:00 +0100 5552857 http://www.medworm.com/index.php?rid=5552858&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22201554%26dopt%3DAbstract Conclusions Stem cells in different compartments share properties such as pluripotency, self-renewal, and diminished regenerative potential in old age. Our model of ovarian stem cell aging suggests that menopause is driven by an age-related decline in ovarian stem cell function rather than depletion of a non-renewable follicular reserve. Understanding how ovarian stem cells interact with their surrounding environment moves us a step closer to controlling the female biological clock when it might be clinically desirable. PMID: 22201554 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5552858 Wed, 28 Dec 2011 05:00:00 +0100 5552858 http://www.medworm.com/index.php?rid=5552860&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22200104%26dopt%3DAbstract Conclusion German gynecologists generally have a positive attitude towards HRT, but find it important to focus on the evaluation of the risk-benefit ratio. The major barriers to prescription are multiple concerns of the patients resulting from non-objective media. PMID: 22200104 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5552860 Tue, 27 Dec 2011 05:00:00 +0100 5552860 http://www.medworm.com/index.php?rid=5538533&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22191384%26dopt%3DAbstract Conclusion Diet, physical exercise and a daily oral intake of soy isoflavones exerted a beneficial effect on the homeostatic model in postmenopausal women which was not related to significant changes in plasma leptin levels, despite a decrease in TNF-α, fat mass and Kupperman values. PMID: 22191384 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538533 Fri, 23 Dec 2011 05:00:00 +0100 5538533 http://www.medworm.com/index.php?rid=5538532&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22191426%26dopt%3DAbstract Conclusion We conclude that smoking reduces serum estrogens at both trough and after 2 h in postmenopausal women on estrogen treatment. The effect of smoking on estrogen concentrations is fully expressed in women smoking ten or less cigarettes daily. These findings indicate that the influence of smoking upon the metabolism of estrogen therapy is constant and without dose-response for standard smoking intensities. PMID: 22191426 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538532 Fri, 23 Dec 2011 05:00:00 +0100 5538532 http://www.medworm.com/index.php?rid=5538531&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22191462%26dopt%3DAbstract Conclusions Because bothersome symptoms and side-effects are a major reason for discontinuation and non-adherence to treatment, symptoms should be monitored and addressed by oncologists so that the breast cancer patient can maintain her quality of life and remain adherent to the treatment schedule. PMID: 22191462 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538531 Fri, 23 Dec 2011 05:00:00 +0100 5538531 http://www.medworm.com/index.php?rid=5538530&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22192068%26dopt%3DAbstract Conclusions Myo-inositol might be considered one of the insulin-sensitizing substances in the treatment of metabolic syndrome. PMID: 22192068 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538530 Fri, 23 Dec 2011 05:00:00 +0100 5538530 http://www.medworm.com/index.php?rid=5538535&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22185471%26dopt%3DAbstract Conclusion The present study provides strong evidence for melatonin supplementation therapy to be more potent and effective in comparison to estrogen replacement therapy due to its single-handed ability to revert all the ovariectomy-induced changes. No reported side-effect or long-term effect of melatonin, against the known effects of estrogen replacement therapy, make it more attractive as a candidate to treat postmenopausal symptoms. PMID: 22185471 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538535 Tue, 20 Dec 2011 05:00:00 +0100 5538535 http://www.medworm.com/index.php?rid=5538534&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22185516%26dopt%3DAbstract Conclusion Serum magnesium level appears to be associated with xerostomia in menopause. PMID: 22185516 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538534 Tue, 20 Dec 2011 05:00:00 +0100 5538534 http://www.medworm.com/index.php?rid=5538536&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175297%26dopt%3DAbstract Conclusion Uncalibrated measures of thoracic spine vBMD obtained from CT scans of the heart may provide clinically relevant information about bone health and osteoporosis/osteopenia risk in recently menopausal women. PMID: 22175297 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538536 Sat, 17 Dec 2011 05:00:00 +0100 5538536 http://www.medworm.com/index.php?rid=5538537&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22168244%26dopt%3DAbstract Conclusion Postmenopausal women have a low understanding of vaginal atrophy. Medical practitioners should proactively raise this topic, help patients to understand that vaginal atrophy is a chronic condition, and discuss treatment options. Country-specific approaches may be required. PMID: 22168244 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538537 Wed, 14 Dec 2011 05:00:00 +0100 5538537 http://www.medworm.com/index.php?rid=5538538&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22148909%26dopt%3DAbstract Conclusions There are safe non-hormonal conventional treatments for menopausal VMS, although they are less efficacious than estrogens. The indication of phytochemicals is for women who make this choice on personal beliefs; long-term studies of larger groups of patients are needed to assess safety. PMID: 22148909 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5538538 Thu, 08 Dec 2011 05:00:00 +0100 5538538 http://www.medworm.com/index.php?rid=5479327&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22141325%26dopt%3DAbstract Conclusions Menopausal symptoms evaluated by a validated climacteric scale are associated with a worsening of biochemical risk factors for atherosclerosis and cardiovascular disease. PMID: 22141325 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479327 Mon, 05 Dec 2011 05:00:00 +0100 5479327 http://www.medworm.com/index.php?rid=5479326&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22141363%26dopt%3DAbstract Conclusions ER gene PvuII and XbaI polymorphisms have no major influence on bone mineral density in our group of postmenopausal women. PMID: 22141363 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479326 Mon, 05 Dec 2011 05:00:00 +0100 5479326 http://www.medworm.com/index.php?rid=5479325&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22142402%26dopt%3DAbstract This article attempts to reduce the anxiety-inducing barrage of these reports by orienting physicians to better understand the validity of reported breast cancer risk factors. We hope to provide this understanding by: explaining the difference between relative and absolute risk, encouraging application of the 95% confidence interval to better evaluate the statistical validity of any given risk factor; placing the reported risk factors in the context of an accepted risk factor like cigarette smoking and lung cancer; and communicating the limits of statistical validity in the absence of reproducibility. This review will, to a small degree, provide a balance to the reports currently dominating the literature. PMID: 22142402 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479325 Mon, 05 Dec 2011 05:00:00 +0100 5479325 http://www.medworm.com/index.php?rid=5479331&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136260%26dopt%3DAbstract Conclusions Although prior cosmetic breast surgery was reported by few women, breast cancer was diagnosed in two women during the procedure. Surgeons performing elective breast surgery need to understand and apply consistent, reliable breast cancer screening practices. PMID: 22136260 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479331 Sat, 03 Dec 2011 05:00:00 +0100 5479331 http://www.medworm.com/index.php?rid=5479338&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132704%26dopt%3DAbstract Authors: Gambacciani M Abstract A new study by Karim and colleagues has highlighted the intriguing issue of the consequences of cessation of long-term postmenopausal hormone use. While potential reductions in breast cancer risk and in the incidence of newly diagnosed breast cancer in the era after the Women's Health Initiative study have been heavily debated, the implications of withdrawal from hormone therapy for bone health and fracture risk have remained outside the main scope. This new study has now demonstrated that there is a very clear downside in skeletal outcome that should be considered while evaluating the pros and cons of discontinuing hormone therapy. During 532 686 person-years of observation and a follow-up period of 6.5 years, a 55% increased risk for hip fracture w... Climacteric journals http://www.medworm.com/rss/comments.php?id=5479338 Thu, 01 Dec 2011 05:00:00 +0100 5479338 http://www.medworm.com/index.php?rid=5479337&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132727%26dopt%3DAbstract Conclusions There is no clear evidence that the menopause transition alone increases the risk of clinically significant affective disorders, except in women with risk factors such as psychosocial stressors, severe and prolonged vasomotor symptoms and a previous history of affective disorders. Nevertheless, anxiety and depression are common in women and clinicians should be alert to the symptoms of these conditions at all encounters. PMID: 22132727 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479337 Thu, 01 Dec 2011 05:00:00 +0100 5479337 http://www.medworm.com/index.php?rid=5479336&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132748%26dopt%3DAbstract Conclusions Carotid IMT, a surrogate marker of subclinical atherosclerosis and cardiovascular risk, was found to be increased in women with vasomotor symptoms as compared to asymptomatic women. This association was independent of cardiovascular risk factors or endogenous hormone levels. It remains to be elucidated whether the presence of menopausal symptoms is an additional cardiovascular risk factor requiring preventive intervention. PMID: 22132748 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479336 Thu, 01 Dec 2011 05:00:00 +0100 5479336 http://www.medworm.com/index.php?rid=5479335&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132771%26dopt%3DAbstract Conclusions This information should be used to develop interventions and health awareness materials about HRT in clinical postmenopausal women. PMID: 22132771 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479335 Thu, 01 Dec 2011 05:00:00 +0100 5479335 http://www.medworm.com/index.php?rid=5479334&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132797%26dopt%3DAbstract Conclusion We conclude that certain breast cancer risk factors may vary by molecular subtypes. According to our results, HRT use may have a greater influence on HR (+) and HER2(-) breast cancers and the risk of HER2-defined breast cancer may differ with respect to the regimen of HRT. PMID: 22132797 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479334 Thu, 01 Dec 2011 05:00:00 +0100 5479334 http://www.medworm.com/index.php?rid=5479333&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132829%26dopt%3DAbstract Authors: Koloszar S, Pal Z, Kereszturi A, Vajda G, Pal A, Daru J Abstract The aromatase inhibitor anastrazole proved effective in the treatment of endometrial hyperplasia and postmenopausal bleeding in an obese 65-year-old woman with high operative risk. During anastrazole administration for 12 months, the endometrial thickness decreased from 9.8 mm to 2.4 mm and the control endometrial histology showed an atrophic endometrium. Uterine bleeding did not occur in the post-treatment, 3-year follow-up period. The endometrial thicknesses measured yearly by ultrasonography were 2.9, 3.5 and 3.3 mm. The plasma estradiol levels increased from < 73 pmol/l post-treatment to 112, 98 and 103 pmol/l. This case demonstrates that long-term aromatase inhibitor treatment can result in a refracto... Climacteric journals http://www.medworm.com/rss/comments.php?id=5479333 Thu, 01 Dec 2011 05:00:00 +0100 5479333 http://www.medworm.com/index.php?rid=5479332&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22132862%26dopt%3DAbstract Conclusion While information needs regarding breast cancer appear well met in younger women, unmet information needs regarding menopause after breast cancer persist. Further education and support are required for these women to optimize health screening and prevention behaviors and to ensure informed decision-making regarding menopause treatment options. PMID: 22132862 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479332 Thu, 01 Dec 2011 05:00:00 +0100 5479332 http://www.medworm.com/index.php?rid=5479330&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22074007%26dopt%3DAbstract Authors: Panay N PMID: 22074007 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479330 Thu, 01 Dec 2011 05:00:00 +0100 5479330 http://www.medworm.com/index.php?rid=5479329&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22074008%26dopt%3DAbstract Authors: Panay N Abstract ABSTRACT An integrated approach can be employed when counselling women about menopausal management options, where lifestyle, complementary therapies and hormone replacement therapy (HRT) are discussed. Women might opt to use an alternative approach to HRT for a variety of reasons, e.g. fear of side-effects and risks or contraindications to HRT. There are many choices of dietary and herbal approaches for menopausal symptoms, which essentially divide into food supplements and herbal medicines. The choice can often be overwhelming and confusing for the woman. Of concern, the evidence for efficacy and safety of some of these complementary therapies can be extremely limited or non-existent. In order to enable women to make a fully informed choice, it is impor... Climacteric journals http://www.medworm.com/rss/comments.php?id=5479329 Thu, 01 Dec 2011 05:00:00 +0100 5479329 http://www.medworm.com/index.php?rid=5479328&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22074009%26dopt%3DAbstract This report includes insights into how women feel about their menopause management, in particular their need to make an informed decision about their menopause management. This will ensure that they are committed to the option selected. Non-drug options should be viewed as a different approach to HRT, not as a substitute, and they should be recommended specifically to ensure that quality is assured. A guide is included as to how to select non-drug options, in particular for the phytoestrogen supplement products. Our role as physicians is to offer our patients the best possible choices to manage their health, and this should now include non-drug options that have been well-researched in terms of efficacy and safety. PMID: 22074009 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5479328 Thu, 01 Dec 2011 05:00:00 +0100 5479328 http://www.medworm.com/index.php?rid=5427944&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085236%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 22085236 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427944 Sun, 20 Nov 2011 08:48:46 +0100 5427944 http://www.medworm.com/index.php?rid=5427943&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085237%26dopt%3DAbstract Authors: Pines A PMID: 22085237 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427943 Sun, 20 Nov 2011 08:48:37 +0100 5427943 http://www.medworm.com/index.php?rid=5427942&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085238%26dopt%3DAbstract Womenopause: Stop pausing and start living Lovera Wolf Miller and David C. Miller Published in 2010 by O-Books , UK ISBN 978 1 84694 321 8 429 pages, paperback; ?12.99 , US $24.95. Climacteric. 2011 Dec;14(6):696 Authors: Fenton A PMID: 22085238 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427942 Sun, 20 Nov 2011 08:48:28 +0100 5427942 http://www.medworm.com/index.php?rid=5427941&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085239%26dopt%3DAbstract Authors: Maclennan AH, Morris D Abstract This educational and entertaining quiz on menopausal management issues involves delegate interaction and debate and was designed for The Australasian Menopause Society Annual Congress in 2011. Multidisciplinary groups of delegates discussed each question and, after 2 minutes, their team captain electronically voted for the team's consensus as to the best answer. The quiz is called an ?Ambrose OSCE?. ?Ambrose? comes from the golf competition where the team's ?best shot? is chosen and ?OSCE? is from Oral Structured Clinical Exams. The distributions of the teams? answers were displayed to the audience and the panel member who set each question explained why they allocated marks between 22 and +2 to these answers, e.g. 22 for an out-of-bounds an... Climacteric journals http://www.medworm.com/rss/comments.php?id=5427941 Sun, 20 Nov 2011 08:48:19 +0100 5427941 http://www.medworm.com/index.php?rid=5427940&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085240%26dopt%3DAbstract Authors: PMID: 22085240 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427940 Sun, 20 Nov 2011 08:48:11 +0100 5427940 http://www.medworm.com/index.php?rid=5427950&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066752%26dopt%3DAbstract Conclusion Isoflavones extracted from Glycine max soy bean, in vitro, presented antiatherogenic effects, reducing the expression of adhesion molecules and acting as preventive agents as well as therapeutic agents. PMID: 22066752 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427950 Tue, 08 Nov 2011 05:00:00 +0100 5427950 http://www.medworm.com/index.php?rid=5427949&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066790%26dopt%3DAbstract Conclusions Desvenlafaxine did not separate from placebo in reducing the number of moderate to severe hot flushes at week 12, although it did allow women to achieve 50% reduction sooner than placebo. Tibolone did separate from placebo, but with smaller than expected effect. The placebo effect was high (57%). Adverse drug reactions were consistent with the known safety profile of desvenlafaxine, and significantly more women who received tibolone experienced episodes of bleeding compared with women who received desvenlafaxine or placebo. PMID: 22066790 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427949 Tue, 08 Nov 2011 05:00:00 +0100 5427949 http://www.medworm.com/index.php?rid=5427948&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066827%26dopt%3DAbstract Conclusion PPE is a possible option as an adjunctive oral supplement in the case of HRT-resistant, long-lasting knee pain. PMID: 22066827 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427948 Tue, 08 Nov 2011 05:00:00 +0100 5427948 http://www.medworm.com/index.php?rid=5427947&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066863%26dopt%3DAbstract Conclusion This study confirms lower DXR-BMD in Indian subjects with fragility fractures. This may have a potential role in fracture prediction when used with clinical risk factors in the Indian population. PMID: 22066863 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427947 Tue, 08 Nov 2011 05:00:00 +0100 5427947 http://www.medworm.com/index.php?rid=5427946&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066898%26dopt%3DAbstract Conclusion Based on this study, there were similar positive results for treatment with the vaginal cone and pelvic floor muscle training for urinary leakage, pelvic floor muscle pressure and quality of life for postmenopausal women with stress urinary incontinence after 6 weeks. PMID: 22066898 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427946 Tue, 08 Nov 2011 05:00:00 +0100 5427946 http://www.medworm.com/index.php?rid=5427945&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22066937%26dopt%3DAbstract Conclusion Our findings may in part reflect the molecular processes contributing to the safe profile of hormone therapy, tibolone and raloxifene in cervical carcinogenesis. PMID: 22066937 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5427945 Tue, 08 Nov 2011 05:00:00 +0100 5427945 http://www.medworm.com/index.php?rid=5363512&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22023082%26dopt%3DAbstract Conclusions The results of the present study suggest that the RANK and RANKL are two candidate genes for AAM in Chinese women. PMID: 22023082 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363512 Mon, 24 Oct 2011 04:00:00 +0100 5363512 http://www.medworm.com/index.php?rid=5363518&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017273%26dopt%3DAbstract Conclusions LNG-IUS counters endometrial proliferation and causes regression of and prevents endometrial hyperplasia in selected groups of women. There is, however, insufficient evidence to recommend LNG-IUS as the treatment of choice for hyperplasia and no evidence to adequately support its use as chemoprevention in women with hereditary non-polyposis colorectal cancer syndrome or obesity. PMID: 22017273 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363518 Sun, 23 Oct 2011 04:00:00 +0100 5363518 http://www.medworm.com/index.php?rid=5363517&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017297%26dopt%3DAbstract Conclusions Strong predictors of the worse quality of life established in the research make it possible to single out a group of women who need special attention in the process of undertaking preventive or curative steps. PMID: 22017297 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363517 Sun, 23 Oct 2011 04:00:00 +0100 5363517 http://www.medworm.com/index.php?rid=5363516&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017318%26dopt%3DAbstract Conclusion The TM group exhibited improved subjective data considering the changes in symptoms according to the ISI and the MENQOL and a decrease in symptoms according to the BDI. PMID: 22017318 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363516 Sun, 23 Oct 2011 04:00:00 +0100 5363516 http://www.medworm.com/index.php?rid=5363515&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017345%26dopt%3DAbstract Conclusion Levels of ER-α and VIP expression in the posterior vaginal wall were higher in premenopausal than in menopausal women, but VIP expression was not associated with estrogen status. Age was an independent predictor of VIP staining in vaginal wall biopsies. PMID: 22017345 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363515 Sun, 23 Oct 2011 04:00:00 +0100 5363515 http://www.medworm.com/index.php?rid=5363514&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017369%26dopt%3DAbstract Conclusions These preliminary data indicate that nitric oxide appears not to be a factor in hot flushes and might not be related to their etiology. Since a fasting plasma NOx measurement may not reflect what happens at the time of the hot flush episode, in future studies there should be an attempt to assess nitric oxide release during a concomitant hot flush. PMID: 22017369 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363514 Sun, 23 Oct 2011 04:00:00 +0100 5363514 http://www.medworm.com/index.php?rid=5363513&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22017387%26dopt%3DAbstract Conclusions Treatment with the complex remedy for 12 or 24 weeks did not result in clinically significant improvement of menopausal symptoms. PMID: 22017387 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363513 Sun, 23 Oct 2011 04:00:00 +0100 5363513 http://www.medworm.com/index.php?rid=5363525&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21995678%26dopt%3DAbstract Conclusion This research emphasizes that severity measurement of symptoms should account for both frequency and intensity. Moreover, it contributes a fully validated 12-dimenson inventory for menopausal symptoms, the Menopause Symptoms' Severity Inventory-38. Regarding differences between peri- and postmenopausal women, the increment in symptoms only happens in physical symptoms, although the severity levels are not exacerbated. PMID: 21995678 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363525 Thu, 13 Oct 2011 04:00:00 +0100 5363525 http://www.medworm.com/index.php?rid=5363526&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985779%26dopt%3DAbstract Conclusion Short-term oral hormone treatment has no impact on the cellular immune response but, concerning the humoral immune response, immunoglobulin G decreased and the levels of IL-10 were significantly higher. PMID: 21985779 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363526 Mon, 10 Oct 2011 04:00:00 +0100 5363526 http://www.medworm.com/index.php?rid=5363524&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22016891%26dopt%3DAbstract Authors: Davis S PMID: 22016891 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363524 Sat, 01 Oct 2011 04:00:00 +0100 5363524 http://www.medworm.com/index.php?rid=5363523&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22016892%26dopt%3DAbstract Authors: Yankelevich D PMID: 22016892 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363523 Sat, 01 Oct 2011 04:00:00 +0100 5363523 http://www.medworm.com/index.php?rid=5363522&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22016893%26dopt%3DAbstract Authors: Studd J PMID: 22016893 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363522 Sat, 01 Oct 2011 04:00:00 +0100 5363522 http://www.medworm.com/index.php?rid=5363521&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22016894%26dopt%3DAbstract Authors: de Villiers TJ PMID: 22016894 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363521 Sat, 01 Oct 2011 04:00:00 +0100 5363521 http://www.medworm.com/index.php?rid=5363520&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22016895%26dopt%3DAbstract Authors: Kendler D PMID: 22016895 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363520 Sat, 01 Oct 2011 04:00:00 +0100 5363520 http://www.medworm.com/index.php?rid=5363519&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22016896%26dopt%3DAbstract Authors: Pérez-López FR, Chedraui P PMID: 22016896 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5363519 Sat, 01 Oct 2011 04:00:00 +0100 5363519 http://www.medworm.com/index.php?rid=5221570&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21910669%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 21910669 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5221570 Thu, 15 Sep 2011 23:48:41 +0100 5221570 http://www.medworm.com/index.php?rid=5221569&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21910670%26dopt%3DAbstract Authors: Muin DA, Metka MM, Huber JC PMID: 21910670 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5221569 Thu, 15 Sep 2011 23:48:31 +0100 5221569 http://www.medworm.com/index.php?rid=5221568&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21910671%26dopt%3DAbstract Authors: Kerber IJ, Turner RJ PMID: 21910671 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5221568 Thu, 15 Sep 2011 23:48:20 +0100 5221568 http://www.medworm.com/index.php?rid=5221567&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21910672%26dopt%3DAbstract Authors: Pines A PMID: 21910672 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5221567 Thu, 15 Sep 2011 23:48:11 +0100 5221567 http://www.medworm.com/index.php?rid=5180350&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21878053%26dopt%3DAbstract Authors: Studd JW Abstract ABSTRACT Premenstrual depression, postnatal depression and climacteric depression are related to changes in ovarian hormone levels and can be effectively treated by hormones. It is unfortunate that psychiatrists have not accepted this form of treatment and this paper is an attempt to simplify this treatment, which should include transdermal estrogens, possibly testosterone and, if the woman has a uterus, also progestogen. A balance is often necessary between these three hormones. Transdermal estrogens in the appropriate dose will suppress ovulation and suppress the cyclical hormonal changes that produce premenstrual depression. Estrogens also have a mood-enhancing effect in postnatal depression and the depression in the transitional phase of the menopause... Climacteric journals http://www.medworm.com/rss/comments.php?id=5180350 Tue, 30 Aug 2011 23:00:00 +0100 5180350 http://www.medworm.com/index.php?rid=5180349&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21878054%26dopt%3DAbstract Conclusion The majority of Serbian women attending health-care centers have abdominal obesity and metabolic syndrome which significantly increase in prevalence in the perimenopausal years. This indicates that preventive measures should be focused on diabetes and cardiovascular disease in the perimenopause. PMID: 21878054 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5180349 Tue, 30 Aug 2011 23:00:00 +0100 5180349 http://www.medworm.com/index.php?rid=5160348&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21861771%26dopt%3DAbstract Conclusions Sertraline was more effective than placebo in the management of the somatic and psychological complaints of the climacteric syndrome. PMID: 21861771 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5160348 Tue, 23 Aug 2011 23:00:00 +0100 5160348 http://www.medworm.com/index.php?rid=5160347&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21864135%26dopt%3DAbstract Authors: Stevenson JC, Hodis HN, Pickar JH, Lobo RA Abstract ABSTRACT A new analysis from the Women's Health Initiative included data on breast cancer incidence over a 11-year period from the randomized trial of conjugated equine estrogens (CEE) plus medroxyprogesterone acetate (MPA) and a subsequent observational follow-up. The conclusions were that CEE/MPA use was associated with an increase in both breast cancer incidence and mortality. We have concerns over the validity of their statistical analyses, as adjustments for baseline characteristics or for multiple comparisons demonstrate no significant differences in incidence between those allocated to CEE/MPA or placebo. We suspect that the apparent increase in mortality is the result of surveillance and detection bias rather than... Climacteric journals http://www.medworm.com/rss/comments.php?id=5160347 Tue, 23 Aug 2011 23:00:00 +0100 5160347 http://www.medworm.com/index.php?rid=5160346&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21864136%26dopt%3DAbstract Conclusions Despite low follicle numbers, the aging macaque ovary retains the necessary proteins for androgenesis within residual stromal cells and contributes to peripheral androgen concentrations. PMID: 21864136 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5160346 Tue, 23 Aug 2011 23:00:00 +0100 5160346 http://www.medworm.com/index.php?rid=5160345&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21864137%26dopt%3DAbstract Conclusion While phytoestrogens combined with mixed exercise were not sufficient to improve menopausal symptoms, it seemed to be a better strategy than exercise alone to improve the general quality of life in postmenopausal women. PMID: 21864137 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5160345 Tue, 23 Aug 2011 23:00:00 +0100 5160345 http://www.medworm.com/index.php?rid=5160349&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854296%26dopt%3DAbstract Conclusion Depression, anxiety, body image, sexual dysfunction and self-confidence are compromised for women across different groups of premature menopause. Understanding these differences is important to the development of individual management plans based on the needs of women. PMID: 21854296 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5160349 Sat, 20 Aug 2011 23:00:00 +0100 5160349 http://www.medworm.com/index.php?rid=5142754&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21848495%26dopt%3DAbstract Conclusions Vasomotor symptoms are experienced by women of all ethnic groups. They are caused by changes in the central nervous system associated with estrogen withdrawal and are best treated with estrogen replacement therapy. Objective monitoring of hot flushes indicates that placebo has little to no effect on their improvement. Subjective assessments of hot flushes in clinical trials may be inaccurate based on objective measurement of the frequency of hot flushes. Based on preliminary reports, women experiencing hot flushes have an increased risk of cardiovascular disease and a reduced incidence of breast cancer. PMID: 21848495 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5142754 Wed, 17 Aug 2011 23:00:00 +0100 5142754 http://www.medworm.com/index.php?rid=5142753&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21848496%26dopt%3DAbstract Authors: Pines A Abstract ABSTRACT Although the exact etiology of hot flushes and night sweats has not been fully clarified, the intriguing question whether vasomotor symptoms (VMS) are markers of coronary artery disease risk has been evaluated in several studies. Surrogate metabolic and hemodynamic parameters point at adverse alterations in flushers, but the results related to clinical endpoints are not unidirectional. Recent relevant data come from the Women's Health Initiative (WHI) observational study (60 000 women, mean age 63 years, mean follow-up period 10 years). Women with VMS only at onset of menopause but not at enrollment to the WHI study had a modest, yet significant decreased risk of stroke, total cardiovascular disease events, and all-cause mortality, compared with w... Climacteric journals http://www.medworm.com/rss/comments.php?id=5142753 Wed, 17 Aug 2011 23:00:00 +0100 5142753 http://www.medworm.com/index.php?rid=5142752&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21848497%26dopt%3DAbstract Conclusions Low-dose maintenance therapy that was half the standard dose of transdermal E2 gel (0.9 g/day) applied to women who had achieved marked improvement in the number of hot flushes at the standard dose (1.8 g/day) was demonstrated to be effective (inhibition of recurrence) and safe for the treatment of climacteric disorder and estrogen deficiency symptoms. PMID: 21848497 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5142752 Wed, 17 Aug 2011 23:00:00 +0100 5142752 http://www.medworm.com/index.php?rid=5069322&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21762005%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 21762005 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5069322 Wed, 27 Jul 2011 20:46:40 +0100 5069322 http://www.medworm.com/index.php?rid=5069321&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21762006%26dopt%3DAbstract Conclusions This study examined women's perceptions of premature ovarian failure, its impact and the services they received. The results can be used to inform service reconfiguration and improvement. PMID: 21762006 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5069321 Wed, 27 Jul 2011 20:46:20 +0100 5069321 http://www.medworm.com/index.php?rid=5069320&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21762007%26dopt%3DAbstract Authors: PMID: 21762007 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5069320 Wed, 27 Jul 2011 20:45:15 +0100 5069320 http://www.medworm.com/index.php?rid=5019367&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721171%26dopt%3DAbstract Authors: Unni J PMID: 21721171 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5019367 Tue, 31 May 2011 23:00:00 +0100 5019367 http://www.medworm.com/index.php?rid=5019366&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721172%26dopt%3DAbstract Authors: Fisher L PMID: 21721172 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5019366 Tue, 31 May 2011 23:00:00 +0100 5019366 http://www.medworm.com/index.php?rid=5019365&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721173%26dopt%3DAbstract Authors: Pines A PMID: 21721173 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5019365 Tue, 31 May 2011 23:00:00 +0100 5019365 http://www.medworm.com/index.php?rid=5019364&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721174%26dopt%3DAbstract Authors: Chedraui P PMID: 21721174 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5019364 Tue, 31 May 2011 23:00:00 +0100 5019364 http://www.medworm.com/index.php?rid=5019363&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21721175%26dopt%3DAbstract Authors: Archer DF PMID: 21721175 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=5019363 Tue, 31 May 2011 23:00:00 +0100 5019363 http://www.medworm.com/index.php?rid=4971632&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21682008%26dopt%3DAbstract Authors: PMID: 21682008 [PubMed - indexed for MEDLINE] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4971632 Tue, 31 May 2011 23:00:00 +0100 4971632 http://www.medworm.com/index.php?rid=4824313&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21563995%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 21563995 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824313 Mon, 16 May 2011 00:30:21 +0100 4824313 http://www.medworm.com/index.php?rid=4824312&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21563996%26dopt%3DAbstract Authors: Sturdee DW, Pines A PMID: 21563996 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824312 Mon, 16 May 2011 00:30:17 +0100 4824312 http://www.medworm.com/index.php?rid=4824311&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21563997%26dopt%3DAbstract Authors: PMID: 21563997 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824311 Mon, 16 May 2011 00:30:12 +0100 4824311 http://www.medworm.com/index.php?rid=4824310&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21563998%26dopt%3DAbstract Authors: PMID: 21563998 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824310 Mon, 16 May 2011 00:30:07 +0100 4824310 http://www.medworm.com/index.php?rid=4824316&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21545271%26dopt%3DAbstract Conclusion Although many arguments support the hypothesis that the drop in breast cancer incidence can be partly explained by the decrease in HRT use, we were unable to find a strong association between the two in Belgium. PMID: 21545271 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824316 Wed, 04 May 2011 23:00:00 +0100 4824316 http://www.medworm.com/index.php?rid=4824315&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21545272%26dopt%3DAbstract Conclusions Bilateral ovariectomy seems to cause dyslipidemia and serious loss of bone mineral density within only 1 year, and patients who lose ovarian function may require careful medical care. PMID: 21545272 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824315 Wed, 04 May 2011 23:00:00 +0100 4824315 http://www.medworm.com/index.php?rid=4824314&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21545273%26dopt%3DAbstract Conclusion This pilot study showed pumpkin seed oil had some benefits for postmenopausal women and provided strong evidence to support further studies. PMID: 21545273 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824314 Wed, 04 May 2011 23:00:00 +0100 4824314 http://www.medworm.com/index.php?rid=4824318&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21469973%26dopt%3DAbstract Conclusions Daily treatment of postmenopausal Chinese women with DRSP/E2 for 16 weeks significantly reduced the incidence of hot flushes and demonstrated advantages vs. placebo for other climacteric symptoms. These results indicate that DRSP/E2 is effective, safe and well tolerated in postmenopausal Chinese women. PMID: 21469973 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824318 Tue, 05 Apr 2011 23:00:00 +0100 4824318 http://www.medworm.com/index.php?rid=4824317&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21469974%26dopt%3DAbstract Conclusion A 24-week course of drospirenone with 17β-estradiol resulted in low proliferation and was shown to lead to atrophic endometrium. The novel progestogen drospirenone seems to have favorable effects on the endometrium of postmenopausal women due to its pro-apoptotic action in glandular epithelium. PMID: 21469974 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4824317 Tue, 05 Apr 2011 23:00:00 +0100 4824317 http://www.medworm.com/index.php?rid=4607449&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21410312%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 21410312 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607449 Fri, 18 Mar 2011 18:45:16 +0100 4607449 http://www.medworm.com/index.php?rid=4607448&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21410313%26dopt%3DAbstract Authors: PMID: 21410313 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607448 Fri, 18 Mar 2011 18:45:12 +0100 4607448 http://www.medworm.com/index.php?rid=4607447&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21410314%26dopt%3DAbstract Authors: PMID: 21410314 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607447 Fri, 18 Mar 2011 18:45:07 +0100 4607447 http://www.medworm.com/index.php?rid=4607451&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21401440%26dopt%3DAbstract Conclusions Menopausal symptoms among young breast cancer patients who experience menopausal transition due to adjuvant treatment are associated with a number of sociodemographic, lifestyle and treatment-related factors. Carefully designed interventions to prevent or alleviate these symptoms should take these factors into account. PMID: 21401440 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607451 Tue, 15 Mar 2011 00:00:00 +0100 4607451 http://www.medworm.com/index.php?rid=4607450&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21401441%26dopt%3DAbstract Conclusion Lifestyle factors and medical history have significant influence on BMD in older postmenopausal Chinese women. The influence of gynecological and obstetric history was relatively small. PMID: 21401441 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607450 Tue, 15 Mar 2011 00:00:00 +0100 4607450 http://www.medworm.com/index.php?rid=4607455&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21395451%26dopt%3DAbstract Authors: Tan DA Recently published data demonstrate major demographic changes and disease trends evolving in the Asia-Pacific. These portentous developments will have far-reaching social and economic implications in terms of income security, social welfare and medical services. The region is now home to more than half of the world's population and includes some of the richest and most developed countries alongside some of the poorest and least developed ones. In the coming decades, the number of older persons (aged 60 years or over) and the number of the oldest-old (aged ≥80 years) in the region will increase rapidly. The Asia-Pacific is first in rank in terms of the number of urban dwellers. Despite persisting levels of underweight in some countries in the Asia-Pacific, overweight a... Climacteric journals http://www.medworm.com/rss/comments.php?id=4607455 Sun, 13 Mar 2011 00:00:00 +0100 4607455 http://www.medworm.com/index.php?rid=4607454&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21395452%26dopt%3DAbstract Conclusions Although having good social support in general, some respondents felt less supported about the menopause and felt that improved support networks would diminish some of the confusion about symptoms experienced and management strategies available. In spite of the negative publicity surrounding HRT in recent years, a number of women perceived their family doctor as too restrictive when prescribing HRT. PMID: 21395452 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607454 Sun, 13 Mar 2011 00:00:00 +0100 4607454 http://www.medworm.com/index.php?rid=4607453&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21395454%26dopt%3DAbstract Conclusion Our data suggest that the CYP17 polymorphism did not influence the action of estrogen on menopause symptoms during the 1-year treatment. The extra production of estrogen and androgen may have been countered by the elevation of SHBG levels. PMID: 21395454 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607453 Sun, 13 Mar 2011 00:00:00 +0100 4607453 http://www.medworm.com/index.php?rid=4607452&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21395455%26dopt%3DAbstract Authors: Shah D PMID: 21395455 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607452 Sun, 13 Mar 2011 00:00:00 +0100 4607452 http://www.medworm.com/index.php?rid=4607457&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21375453%26dopt%3DAbstract Conclusions The results demonstrate that various progestogens have different effects on growth of breast tumor cells, especially with the combined usage of E(2). Progestogen-induced apoptosis may be partly inhibited with the presence of E(2), but less severe with lower E(2) concentrations. Therefore, the choice of progestogens, as well as the doses of E(2) and/or progestogen, may influence breast cancer risk. PMID: 21375453 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607457 Sat, 05 Mar 2011 00:00:00 +0100 4607457 http://www.medworm.com/index.php?rid=4607456&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21375454%26dopt%3DAbstract Authors: Pines A Apart from the well-established associations between smoking and increased risk for cardio- and cerebrovascular diseases, chronic obstructive lung disease and smoking-related cancers, it appears that cigarette smoking is also associated with dementia, deficiencies in executive functions, cognitive flexibility, general intellectual abilities, learning and/or memory processing speed, and working memory. These smoking-related neurological disturbances appear in both men and women to a similar extent and in all races. PMID: 21375454 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4607456 Sat, 05 Mar 2011 00:00:00 +0100 4607456 http://www.medworm.com/index.php?rid=4545287&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21355685%26dopt%3DAbstract Authors: Maclennan AH Many traditional contraindications to hormone replacement therapy (HRT) are based on the theoretical potential for these hormones to worsen a disease process and are rarely based on supporting data. This review addresses the available data and lack of data that make the prescription of HRT difficult in a variety of common morbidities. In each circumstance, it is assumed that conservative evidence-based therapies have been tried and that menopausal symptoms remain debilitating and are reducing quality of life. Tailoring of the product, dose, route and regimen may avoid some of the theoretical risks of HRT in particular women or conditions and guidelines are given for each co-morbidity. Specifically, it is discussed that tailored HRT may be used without strong evide... Climacteric journals http://www.medworm.com/rss/comments.php?id=4545287 Mon, 28 Feb 2011 00:00:00 +0100 4545287 http://www.medworm.com/index.php?rid=4490119&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21294673%26dopt%3DAbstract Conclusions?Our analysis revealed some differences from the previously published literature, which might reflect underlying demographic changes. Comprehensive medical care in HRT users without pre-existing breast abnormalities probably reduces the incidence of new breast cancer cases in Slovenia. PMID: 21294673 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490119 Mon, 07 Feb 2011 00:00:00 +0100 4490119 http://www.medworm.com/index.php?rid=4490126&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21235419%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 21235419 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490126 Tue, 01 Feb 2011 00:00:00 +0100 4490126 http://www.medworm.com/index.php?rid=4490125&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21235420%26dopt%3DAbstract Authors: Sturdee DW, de Villiers TJ PMID: 21235420 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490125 Tue, 01 Feb 2011 00:00:00 +0100 4490125 http://www.medworm.com/index.php?rid=4490120&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21281244%26dopt%3DAbstract Conclusions Oral daily treatment with drospirenone 2 mg + estradiol 1 mg reduces the risks for ocular diseases and nasal obstruction in postmenopausal women. PMID: 21281244 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490120 Tue, 01 Feb 2011 00:00:00 +0100 4490120 http://www.medworm.com/index.php?rid=4490121&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21271939%26dopt%3DAbstract Conclusion The impairment of carbohydrate metabolism due to an abrupt decrease in natural estrogen levels should be considered before removing the ovaries during hysterectomy in premenopausal patients. PMID: 21271939 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490121 Fri, 28 Jan 2011 00:00:00 +0100 4490121 http://www.medworm.com/index.php?rid=4490122&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21265610%26dopt%3DAbstract Conclusions Clinically significant CAC and spine vBMD are quantifiable from the same scans within the first 3 years of menopause. Additional work is needed to determine how these measurements change with increasing age or with estrogenic treatments. PMID: 21265610 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490122 Tue, 25 Jan 2011 00:00:00 +0100 4490122 http://www.medworm.com/index.php?rid=4490123&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21254911%26dopt%3DAbstract Conclusions Treatment of postmenopausal women with osteoporosis with RLX and ALN, alone and in combination, significantly increased the BMD of the lumbar spine, femoral neck and total hip and reduced markers of bone turnover. However, the effects of combined therapy were more pronounced than those of either monotherapy. On the other hand, RLX had some beneficial effects on lipid metabolism. Both medications, alone or in combination, had similar tolerability and safety profiles. PMID: 21254911 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490123 Sun, 23 Jan 2011 00:00:00 +0100 4490123 http://www.medworm.com/index.php?rid=4490124&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21244215%26dopt%3DAbstract Conclusions Intravaginal DHEA, through local estrogen and androgen formation, causes a rapid and highly efficient effect on pain at sexual activity without systemic exposure of the other tissues, thus avoiding the recently reported systemic effects of estrogens. PMID: 21244215 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4490124 Tue, 18 Jan 2011 00:00:00 +0100 4490124 http://www.medworm.com/index.php?rid=4173352&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21073406%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 21073406 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4173352 Wed, 17 Nov 2010 11:10:21 +0100 4173352 http://www.medworm.com/index.php?rid=4173351&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21073407%26dopt%3DAbstract Authors: Turner RJ, Kerber IJ PMID: 21073407 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4173351 Wed, 17 Nov 2010 11:10:18 +0100 4173351 http://www.medworm.com/index.php?rid=4173350&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21073408%26dopt%3DAbstract Authors: It is essential for the practicing physician to keep up-to-date with knowledge and reading medical journals is an important component in achieving this. Menopause Live, an e-service for IMS members prepared by IMS members, is issued weekly, bringing a short abstract of a recently published study or review followed by a brief personal commentary. The opinions expressed in these commentaries are those of the commentary authors and are not necessarily supported by the IMS. The articles chosen for Menopause Live are selected by a search of the world literature on issues related to menopause medicine. In order to allow all readers of Climacteric to experience this service, some issues of Menopause Live will be included in the Journal in this new section. Amos Pines, Section Editor... Climacteric journals http://www.medworm.com/rss/comments.php?id=4173350 Wed, 17 Nov 2010 11:10:14 +0100 4173350 http://www.medworm.com/index.php?rid=4173349&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21073409%26dopt%3DAbstract Authors: PMID: 21073409 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4173349 Wed, 17 Nov 2010 11:10:11 +0100 4173349 http://www.medworm.com/index.php?rid=4173348&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21073410%26dopt%3DAbstract Authors: PMID: 21073410 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4173348 Wed, 17 Nov 2010 11:10:08 +0100 4173348 http://www.medworm.com/index.php?rid=4173353&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21073356%26dopt%3DAbstract Conclusions A positive family history of thrombosis is a sensitive indicator for selected genetic testing in high-risk women before starting HRT. PMID: 21073356 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4173353 Sat, 13 Nov 2010 00:00:00 +0100 4173353 http://www.medworm.com/index.php?rid=4159096&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21067421%26dopt%3DAbstract Conclusions This research suggests that platinum-based chemotherapy directly induces vascular endothelial dysfunction and may be a risk factor for the development of atherosclerosis. Therefore, gynecologic cancer survivors should be educated about these potential risks, and informed regarding lifestyle modifications that may benefit their general health. PMID: 21067421 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4159096 Thu, 11 Nov 2010 00:00:00 +0100 4159096 http://www.medworm.com/index.php?rid=4159095&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21067422%26dopt%3DAbstract Authors: Pines A The incidence of meningiomas is two to three times higher in women than in men, yet it is a rare event (around one case per 10 000 woman-years). Preclinical and clinical studies point at potential effects of female sex hormones on brain tumors. Results from several prospective, large-scale studies indicate that postmenopausal hormone therapy may increase the risk for diagnosing meningioma by 30-80%, but there is no effect in regard to glioma. However, because of the very low incidence of meningioma in the general population of women, the absolute excess risk attributed to hormone therapy has no clinical impact. PMID: 21067422 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4159095 Thu, 11 Nov 2010 00:00:00 +0100 4159095 http://www.medworm.com/index.php?rid=4110509&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20979461%26dopt%3DAbstract Conclusion In postmenopausal women, E2+DRSP administration improves vasomotor symptoms and general aspects of quality of life and may positively influence cardiovascular risk factors. PMID: 20979461 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4110509 Tue, 26 Oct 2010 23:00:00 +0100 4110509 http://www.medworm.com/index.php?rid=4110508&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20979462%26dopt%3DAbstract Conclusions Non-compliance with HT cessation before screening mammogram was associated with younger age, lower BMI, symptom severity and use of unopposed estrogen. Alternatives for menopause symptom management are needed to assist women with HT cessation. PMID: 20979462 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4110508 Tue, 26 Oct 2010 23:00:00 +0100 4110508 http://www.medworm.com/index.php?rid=4098867&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20964548%26dopt%3DAbstract Conclusion This study revealed that approximately half of the patients treated with raloxifene in regular clinical practice stay on therapy for the first 2 years. Furthermore, the patients do not adhere sufficiently to the recommended dosage, and reduced clinical efficacy in clinical practice is presumable. The reasons for non-adherence comprise tolerability and motivational factors but further investigation is needed. PMID: 20964548 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4098867 Wed, 20 Oct 2010 23:00:00 +0100 4098867 http://www.medworm.com/index.php?rid=4098866&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20964549%26dopt%3DAbstract Authors: Mason RS Vitamin D is principally obtained from skin through the action of ultraviolet B irradiation on 7-dehydrocholesterol. It is further metabolized to 25-hydroxyvitamin D, the major circulating vitamin D compound, and then to 1,25-dihydroxyvitamin D, the hormonal form. The major function of vitamin D compounds is to enhance active absorption of calcium (and phosphate) from the gut, ensuring that bone does not need to be resorbed to maintain blood calcium concentrations despite obligatory urinary losses. Vitamin D compounds have direct effects to enhance bone and muscle function. Based on good evidence, target levels for 25-hydroxyvitamin D in blood are at least 50 nmol/l and there may be a case for higher targets of 75-80 nmol/l. Adequate calcium intakes help to reduce vit... Climacteric journals http://www.medworm.com/rss/comments.php?id=4098866 Wed, 20 Oct 2010 23:00:00 +0100 4098866 http://www.medworm.com/index.php?rid=4098865&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20964550%26dopt%3DAbstract Conclusion TVU is a moderately accurate test in asymptomatic postmenopausal women. Due to its high false-positive rate, its positive results cannot be interpreted. PMID: 20964550 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4098865 Wed, 20 Oct 2010 23:00:00 +0100 4098865 http://www.medworm.com/index.php?rid=4098864&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20964551%26dopt%3DAbstract Conclusion Depression among postmenopausal women is an important public health problem that requires attention; furthermore, women are at risk in terms of depression after entering into menopause. PMID: 20964551 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=4098864 Wed, 20 Oct 2010 23:00:00 +0100 4098864 http://www.medworm.com/index.php?rid=4082570&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20950213%26dopt%3DAbstract Authors: Pines A The latest recommendations on postmenopausal hormone therapy (HT) stress the need first to evaluate the individual benefits and risks and to prescribe the well-informed patient only when the balance is most favorable. As a result of recent studies on the association of lung cancer with HT, this common malignancy was added to the list of potential serious adverse effects of HT. However, data show that estrogen alone does not carry a risk, whereas a combined estrogen + progestin (E + P) regimen may be associated with higher mortality in lung cancer patients. Women usually take HT in the early postmenopausal period and for several years only. No increase in risk was found in E + P users aged 50-59 years, nor for those who used HT for less than 5 years. The abs... Climacteric journals http://www.medworm.com/rss/comments.php?id=4082570 Sun, 17 Oct 2010 23:00:00 +0100 4082570 http://www.medworm.com/index.php?rid=3958853&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20815098%26dopt%3DAbstract Authors: Pines A PMID: 20815098 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3958853 Sat, 11 Sep 2010 22:48:25 +0100 3958853 http://www.medworm.com/index.php?rid=3958852&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20815099%26dopt%3DAbstract Authors: Pickar JH PMID: 20815099 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3958852 Sat, 11 Sep 2010 22:48:21 +0100 3958852 http://www.medworm.com/index.php?rid=3958851&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20815100%26dopt%3DAbstract Authors: Lobo R PMID: 20815100 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3958851 Sat, 11 Sep 2010 22:48:17 +0100 3958851 http://www.medworm.com/index.php?rid=3958850&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20815101%26dopt%3DAbstract Authors: Erel T PMID: 20815101 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3958850 Sat, 11 Sep 2010 22:48:13 +0100 3958850 http://www.medworm.com/index.php?rid=3958849&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20815102%26dopt%3DAbstract Authors: Sturdee D PMID: 20815102 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3958849 Sat, 11 Sep 2010 22:48:10 +0100 3958849 http://www.medworm.com/index.php?rid=3958848&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20815103%26dopt%3DAbstract Authors: Pines A PMID: 20815103 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3958848 Sat, 11 Sep 2010 22:48:06 +0100 3958848 http://www.medworm.com/index.php?rid=3921444&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20738236%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 20738236 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3921444 Wed, 01 Sep 2010 16:45:12 +0100 3921444 http://www.medworm.com/index.php?rid=3921443&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20738237%26dopt%3DAbstract Authors: PMID: 20738237 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3921443 Wed, 01 Sep 2010 16:45:09 +0100 3921443 http://www.medworm.com/index.php?rid=3903971&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20726814%26dopt%3DAbstract Conclusions The CTX-II profile of changes over 3 years may reflect efficacy of strontium ranelate against cartilage degradation, with an enhanced beneficial effect in subjects with early or mild clinical osteoarthritis, probably exerting its putative chondroprotective influence in early stages of the disease. Carefully controlled studies in targeted populations with early osteoarthritis are warranted to assess the role of strontium ranelate halting osteoarthritis progression. PMID: 20726814 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3903971 Sat, 21 Aug 2010 23:00:00 +0100 3903971 http://www.medworm.com/index.php?rid=3858690&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20690864%26dopt%3DAbstract Conclusions There are differences in GAGs in the parametrium, paraurethral tissue and vaginal apex between women in premenopause and those in the postmenopause period. Therefore, 30-day estrogen therapy produces significant differences in levels of hyaluronic acid, dermatan sulfate and chondroitin sulfate. PMID: 20690864 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3858690 Fri, 06 Aug 2010 23:00:00 +0100 3858690 http://www.medworm.com/index.php?rid=3858689&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20690865%26dopt%3DAbstract Conclusions Although tibolone has both gestagenic and androgenic properties together with estrogenic properties, no negative effect on hearing after 6 months of treatment was observed. On the contrary, there was significant improvement in audiometry results at low frequencies after 6 months' treatment. Although statistically not significant, there was some improvement at high frequencies. PMID: 20690865 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3858689 Fri, 06 Aug 2010 23:00:00 +0100 3858689 http://www.medworm.com/index.php?rid=3858688&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20690866%26dopt%3DAbstract Conclusions The majority of the studies suggested a relationship between osteoporosis and periodontitis. Further well-controlled studies are needed to better elucidate the inter-relationship between systemic and oral bone loss and to clarify whether dentists could usefully give an early warning for osteoporosis risk. PMID: 20690866 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3858688 Fri, 06 Aug 2010 23:00:00 +0100 3858688 http://www.medworm.com/index.php?rid=3858687&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20690867%26dopt%3DAbstract Authors: Ceausu I The recent results of the Global Longitudinal Study of Osteoporosis in Women on the lack of self-perceived risk of fracture are just one set of a series of publications that will contribute to the enhancement of osteoporosis assessment and perception and will help to develop new and specific interventions for fracture prevention and ultimately decrease mortality secondary to fractures. The failure of women to appreciate their own risk of fracture is a barrier to receiving appropriate care and safe and effective treatments. The study demonstrates that increased efforts must be made to educate medical professionals and the public including women of any age about the risks of fracture. The importance of osteopenia, osteoporosis and their impact on fractures should be wel... Climacteric journals http://www.medworm.com/rss/comments.php?id=3858687 Fri, 06 Aug 2010 23:00:00 +0100 3858687 http://www.medworm.com/index.php?rid=3858686&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20690868%26dopt%3DAbstract Conclusion There are wide geographical differences in the prevalence of menopausal symptomatology and some differences in the age of onset of menopause. Both in Asia and Latin America, women of poorer socioeconomic status have significantly earlier onset of menopause. Within a geographical region, there are ethnic differences in menopause symptoms. Given differences in study methodologies, firm conclusions are not possible. However, regional differences in age at menopause and in climacteric symptoms are important to acknowledge and lay the foundation for an informed approach to the management of menopause and an understanding of its impact on women's health in the different regions of the world. PMID: 20690868 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3858686 Fri, 06 Aug 2010 23:00:00 +0100 3858686 http://www.medworm.com/index.php?rid=3663658&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20540590%26dopt%3DAbstract Authors: MacLennan A, Sturdee D, Fenton A, Panay N PMID: 20540590 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3663658 Wed, 16 Jun 2010 12:42:12 +0100 3663658 http://www.medworm.com/index.php?rid=3663657&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20540591%26dopt%3DAbstract Authors: Langer RD The dramatic change in opinion on postmenopausal hormone therapy (HT) following initial reports from the Women's Health Initiative (WHI) came about as the 'baby boom' generation of women created the largest population of newly menopausal women in history. That trial of conjugated equine estrogen (CEE) plus medroxyprogesterone acetate (MPA) focused on outcomes in women starting HT a decade or more after menopause. Yet clinical practice has focused on initiation near menopause. Recent findings in the limited numbers of younger menopausal women in the WHI CEE + MPA trial, and findings in the CEE-only trial, suggest that age at initiating HT strongly influences outcomes, and that benefits greatly exceed risk for most women who start within 10 years of menopause. Findings... Climacteric journals http://www.medworm.com/rss/comments.php?id=3663657 Wed, 16 Jun 2010 12:42:08 +0100 3663657 http://www.medworm.com/index.php?rid=3663656&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20540592%26dopt%3DAbstract Authors: Genazzani AR, Pluchino N The marked age-related decline in serum dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) has suggested that a deficiency of these steroids may be causally related to the development of a series of diseases that are generally associated with aging. Postulated consequences of low DHEA levels include insulin resistance, obesity, cardiovascular disease, cancer, reduction of the immune defence system as well as psychosocial problems such as depression and a general deterioration in the sensation of well-being and cognitive function. Clinically, the spectrum of women that would benefit from DHEA therapy is not clearly defined and nor is the dosage of hormone treatment. Whether DHEA therapy could be prescribed as a general anti-aging t... Climacteric journals http://www.medworm.com/rss/comments.php?id=3663656 Wed, 16 Jun 2010 12:42:05 +0100 3663656 http://www.medworm.com/index.php?rid=3516198&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20423241%26dopt%3DAbstract Authors: Panay N, Fenton A PMID: 20423241 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3516198 Fri, 30 Apr 2010 10:24:14 +0100 3516198 http://www.medworm.com/index.php?rid=3516197&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20423242%26dopt%3DAbstract CONCLUSIONS: During 12 weeks' administration, 10 microg vaginal tablets resulted in at least 50% lower mean estradiol concentrations than with the 25 microg dose within 24 h after dosing. Administering the 25 microg dose, mean E2 levels during the first 2 weeks exceeded the published reference range for postmenopausal women using the GCMS method, while, with the 10 microg dose, mean E2 levels remained in that range from the beginning, indicating minimized estradiol absorption. PMID: 20423242 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3516197 Fri, 30 Apr 2010 10:24:11 +0100 3516197 http://www.medworm.com/index.php?rid=3516196&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20423243%26dopt%3DAbstract CONCLUSIONS: After 12 months of treatment with the 10 microg estradiol vaginal tablet, there was no suggestion of endometrial stimulation and no cases of endometrial hyperplasia or cancer reported. This study provides reassuring data on the endometrial safety of treatment with the 10 microg estradiol vaginal tablet for 1 year in a large group of postmenopausal, non-hysterectomized women with vaginal atrophy. PMID: 20423243 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3516196 Fri, 30 Apr 2010 10:24:08 +0100 3516196 http://www.medworm.com/index.php?rid=3516195&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20423244%26dopt%3DAbstract Authors: Cox J PMID: 20423244 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3516195 Fri, 30 Apr 2010 10:24:05 +0100 3516195 http://www.medworm.com/index.php?rid=3460773&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20380569%26dopt%3DAbstract Conclusions As no case of hyperplasia was diagnosed among the 301 interpretable biopsies at 1 year and there was only one case of simple hyperplasia in the 197 post-baseline biopsies at 3 years, the endometrial safety of this extract has been demonstrated. Furthermore, as demonstrated by the lack of change in endometrial thickness associated with the histologic results, we suggest that this extract does not exert a mitogenic effect on the endometrium. These results suggest that daily administration of 70 mg of a specific, standardized isoflavone extract for 3 years could be a safe treatment for both endometrium and breast. PMID: 20380569 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3460773 Fri, 09 Apr 2010 23:00:00 +0100 3460773 http://www.medworm.com/index.php?rid=3292222&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20166858%26dopt%3DAbstract Authors: Fenton A, Panay N PMID: 20166858 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3292222 Mon, 22 Feb 2010 00:12:18 +0100 3292222 http://www.medworm.com/index.php?rid=3292221&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20166859%26dopt%3DAbstract Conclusions TTP was effective in treating HSDD and improving sexual function in this study of naturally menopausal women with and without concurrent hormone therapy. PMID: 20166859 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3292221 Mon, 22 Feb 2010 00:12:13 +0100 3292221 http://www.medworm.com/index.php?rid=3292220&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20166860%26dopt%3DAbstract Authors: PMID: 20166860 [PubMed - in process] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3292220 Mon, 22 Feb 2010 00:12:06 +0100 3292220 http://www.medworm.com/index.php?rid=3280693&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20151791%26dopt%3DAbstract Conclusion The health education program changed the cognitive actions of climacteric women, which resulted in continuously improved menopausal symptoms, quality of life and autonomic nervous system activity. PMID: 20151791 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3280693 Fri, 12 Feb 2010 00:00:00 +0100 3280693 http://www.medworm.com/index.php?rid=3280692&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20151792%26dopt%3DAbstract Conclusion Discontinuation of HT by reducing the daily dose of estrogen for a period of 2 or 4 months did not differ in its effect from that of abrupt cessation with regard to vasomotor symptoms. PMID: 20151792 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3280692 Fri, 12 Feb 2010 00:00:00 +0100 3280692 http://www.medworm.com/index.php?rid=3270357&cid=s_28396_18_f&fid=28396&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148729%26dopt%3DAbstract Conclusion The age of onset of menopause in Nigerian women with type 2 diabetes mellitus is comparable to the age that is commonly reported and the metabolic syndrome is highly prevalent in this group of women. PMID: 20148729 [PubMed - as supplied by publisher] (Source: Climacteric) Climacteric journals http://www.medworm.com/rss/comments.php?id=3270357 Fri, 12 Feb 2010 00:00:00 +0100 3270357