MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Clinical Microbiology Newsletter' source. Thu, 09 Feb 2012 21:34:56 +0100 http://www.medworm.com/index.php?rid=5664686&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439912000062%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5664686 Tue, 07 Feb 2012 02:10:40 +0100 5664686 http://www.medworm.com/index.php?rid=5664685&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439912000050%2Fabstract%3Frss%3Dyes We describe a case of cutaneous infection caused by Scytalidium hyalinum in a 32-year-old patient who was born and raised in Sierra Leone but resided in Spain for the last 10 years. He sought medical attention in our dermatology department for the evaluation of skin lesions that were initially thought to be a contact dermatitis caused by exposure to a chemical irritant. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5664685 Tue, 07 Feb 2012 02:10:40 +0100 5664685 http://www.medworm.com/index.php?rid=5664684&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439912000049%2Fabstract%3Frss%3Dyes This article provides an update of the major CF pathogens and offers a practical laboratory guide that addresses some of the issues encountered with these cultures. Part I of this two-part article reviews the new and most current information gathered from the literature since 2006 with respect to Pseudomonas aeruginosa, Burkholderia cepacia complex, and other glucose non-fermenting gram-negative rods. Part II of this article will complete the review of the key organisms associated with CF infections, including Staphylococcus aureus, nontuberculous mycobacteria, and fungi. Issues regarding susceptibility testing will also be addressed. Finally, a practical laboratory guide will be provided to address some of the confounding issues associated with CF microbiology. (Source: Clinical Microbiol... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5664684 Tue, 07 Feb 2012 02:10:40 +0100 5664684 http://www.medworm.com/index.php?rid=5617586&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439912000037%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5617586 Sun, 22 Jan 2012 02:22:47 +0100 5617586 http://www.medworm.com/index.php?rid=5617585&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439912000025%2Fabstract%3Frss%3Dyes Abstract: Patients undergoing thoracic organ transplantation procedures involving the heart or lung are at increased risk for developing a wide variety of infections due to their underlying immunosuppression and/or other factors. Lung transplant recipients are at high risk for developing infections caused by bacteria, viruses, and opportunistic fungi, whereas heart transplant recipients are at risk for developing infections caused by these same microorganisms, as well as parasitic infections, including toxoplasmosis and New World trypanosomiasis. This review will highlight the various infections that thoracic organ transplant recipients may develop following their procedures. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5617585 Sun, 22 Jan 2012 02:22:47 +0100 5617585 http://www.medworm.com/index.php?rid=5474000&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000547%2Fabstract%3Frss%3Dyes Adiaspiromycosis, 17:131-134 case reports of, 17:132 (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5474000 Mon, 05 Dec 2011 15:39:48 +0100 5474000 http://www.medworm.com/index.php?rid=5473999&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000535%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5473999 Mon, 05 Dec 2011 15:39:48 +0100 5473999 http://www.medworm.com/index.php?rid=5473998&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000523%2Fabstract%3Frss%3Dyes This article reviews the epidemiology, clinical presentation, diagnosis, and treatment of infections caused by this now endemic yeast in the Pacific Northwest. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5473998 Mon, 05 Dec 2011 15:39:48 +0100 5473998 http://www.medworm.com/index.php?rid=5428661&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000511%2Fabstract%3Frss%3Dyes In June 2010, the Clinical and Laboratory Standards Institute (CLSI) published new antimicrobial susceptibility testing interpretive criteria for Enterobacteriaceae and three carbapenems (), lowering the susceptible (S), intermediate (I), and resistant (R) values for imipenem, meropenem, and ertapenem. Ertapenem's S/I/R breakpoints were reduced from 2/4/8 mg/ml to 0.25/0.5/1 mg/ml, respectively. Clinical data from patients infected with Enterobacteriaceae strains with MICs of 0.5 and 1 mg of ertapenem/ml were lacking, resulting in changes that were driven primarily by pharmacokinetic/pharmacodynamic analyses and the desire to ensure that carbapenemase-producing isolates would be categorized as non-susceptible. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5428661 Sun, 20 Nov 2011 14:58:01 +0100 5428661 http://www.medworm.com/index.php?rid=5428660&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991100050X%2Fabstract%3Frss%3Dyes This article presents some considerations for navigating the world of quantitative laboratory-developed assays and proposes a paradigm for developing a quality system for these assays. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5428660 Sun, 20 Nov 2011 14:58:01 +0100 5428660 http://www.medworm.com/index.php?rid=5376658&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000493%2Fabstract%3Frss%3Dyes Abstract: Sepsis is a complex clinical syndrome associated with infection and is a leading cause of death worldwide. Despite the availability of critical care, sepsis continues to challenge health care providers and is becoming increasingly prevalent. While bacterial infections account for the vast majority of cases, identification and resistance profiling of the infecting agent are frequently unavailable at the time of disease onset, which can sometimes confound diagnosis. Pathogenesis is intimately associated with the “cytokine storm,” an uncontrolled response of the immune system, which can lead to hemodynamic instability and organ failure. Clinical signs alone are often insufficient for an early and accurate diagnosis, reducing an already limited window for effective intervent... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5376658 Sat, 05 Nov 2011 03:39:59 +0100 5376658 http://www.medworm.com/index.php?rid=5356066&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991100047X%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5356066 Fri, 28 Oct 2011 07:36:12 +0100 5356066 http://www.medworm.com/index.php?rid=5356065&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000468%2Fabstract%3Frss%3Dyes Abstract: Ceftaroline is a cephalosporin antibiotic with broad-spectrum activity against gram-positive and gram-negative bacteria, including contemporary resistant gram-positive phenotypes, such as methicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant Streptococcus pneumoniae, and penicillin-resistant S. pneumoniae. Ceftaroline is administered as the prodrug ceftaroline fosamil, which is rapidly converted via plasma phosphatases to its bioactive metabolite, ceftaroline. Ceftaroline fosamil was approved in October 2010 by the U.S. Food and Drug Administration (FDA) and launched in March 2011 for the treatment of acute bacterial skin and skin structure infections and for the treatment of community-acquired bacterial pneumonia caused by designated susceptible isolates. ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5356065 Fri, 28 Oct 2011 07:36:12 +0100 5356065 http://www.medworm.com/index.php?rid=5282122&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000456%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5282122 Tue, 04 Oct 2011 15:55:00 +0100 5282122 http://www.medworm.com/index.php?rid=5282121&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000444%2Fabstract%3Frss%3Dyes We present a case of meningitis caused by an MDR strain of Pseudomonas aeruginosa, which exemplifies the risk of treatment failure because of the marked limits in treatment options. Over the last 5 years at our institution, the incidence of resistance has increased from 1.9% in 2005 to 2006 to 7.9% in 2009 to 2010, with a peak incidence of 10.3% in 2007 to 2008. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5282121 Tue, 04 Oct 2011 15:55:00 +0100 5282121 http://www.medworm.com/index.php?rid=5282120&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000432%2Fabstract%3Frss%3Dyes Abstract: Human adenovirus serotype 14 (HAdV-14; agent de Wit), a subspecies B2 member, was first identified in The Netherlands in 1955 in a military training camp and last reported in Eurasia in 1963. This virus has been conspicuous by its absence in global serosurveys and surveillance in subsequent decades. In early 2006, HAdV-14 was described at five military training centers in the United States and was subsequently associated with civilian cases of severe respiratory disease and fatalities in New York and California. In 2007, 140 cases of HAdV-14 were identified in outbreak clusters across the U.S. (Oregon, Washington, and Texas), with 37% requiring hospitalization, 17% admittance to intensive care units, and a 5% mortality rate. Genetic characterization of this emerging HAdV-14 ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5282120 Tue, 04 Oct 2011 15:55:00 +0100 5282120 http://www.medworm.com/index.php?rid=5234345&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000420%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5234345 Tue, 20 Sep 2011 05:24:09 +0100 5234345 http://www.medworm.com/index.php?rid=5234344&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000419%2Fabstract%3Frss%3Dyes Propionibacterium avidum is traditionally considered an organism of low pathogenicity and is seldom associated with human infection. Rare reports of breast abscess caused by P. avidum have been almost exclusively associated with immunosuppression or prior surgical intervention. There are a small number of reports of this organism causing splenic abscess, septic arthritis, sacroiliitis, and osteomyelitis, as well as one report of perianal abscess (). All these infections occurred in immunocompromised patients, patients with pre-existing medical conditions, or following a medical intervention (). The organism has also been associated rarely with breast abscess (), with only one such case being reported in a previously healthy individual who had no history of prior surgical intervention (). (... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5234344 Tue, 20 Sep 2011 05:24:09 +0100 5234344 http://www.medworm.com/index.php?rid=5234343&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000407%2Fabstract%3Frss%3Dyes Abstract: Human adenovirus serotype 14 (HAdV-14; agent de Wit), a subspecies B2 member, was first identified in The Netherlands in 1955 in a military training camp and last reported in Eurasia in 1963. This virus has been conspicuous by its absence in global serosurveys and surveillance in subsequent decades. In early 2006, HAdV-14 was described at five military training centers in the United States and was subsequently associated with civilian cases of severe respiratory disease and fatalities in New York and California. In 2007, 140 cases of HAdV-14 were identified in outbreak clusters across the U.S. (Oregon, Washington, and Texas), with 37% requiring hospitalization, 17% admittance to intensive care units, and a 5% mortality rate. Genetic characterization of this emerging HAdV-14 ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5234343 Tue, 20 Sep 2011 05:24:09 +0100 5234343 http://www.medworm.com/index.php?rid=5191695&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000390%2Fabstract%3Frss%3Dyes This article describes the taxonomic status of the family Pasteurellaceae, especially the members of the genera Pasteurella and Actinobacillus. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5191695 Sun, 04 Sep 2011 04:29:21 +0100 5191695 http://www.medworm.com/index.php?rid=5156691&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000389%2Fabstract%3Frss%3Dyes Adiaspiromycosis is a common fungal infection in mammalian species, especially small rodents, caused by Emmonsia crescens (formerly Chrysosporium parvum var. crescens) () and Emmonsia parva (). Its occurrence in humans is regarded as a rare, self-limiting infection resulting from the inhalation of dust containing spores (aleuriospores) from the ubiquitous temperate zone saprophytic, soil-dwelling, filamentous E. crescens and E. parva (). Upon inhalation into the human or rodent lung, the spores dramatically enlarge without budding and induce a granulomatous response (). Symptomatology in individuals correlates with the size of the spore inoculum inhaled (). Most documented human infections are caused by E. crescens and are confined to the lungs with occasional dissemination within the lung... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5156691 Thu, 25 Aug 2011 10:22:19 +0100 5156691 http://www.medworm.com/index.php?rid=5156690&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000377%2Fabstract%3Frss%3Dyes Abstract: The science of pharmacokinetics-pharmacodynamics (PK-PD) has become critical to clinical decision making and drug development, especially with regard to dose and administration schedule selection and susceptibility breakpoint determination. It is a rapidly growing science, with its roots firmly embedded in laboratory science and branches reaching through regulatory bodies to the patient's bedside. As these concepts form the scientific basis for antimicrobial chemotherapeutics, this brief review will begin by focusing on fundamental PK-PD principles and finish by discussing the application of these concepts for determination of susceptibility testing interpretive criteria. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5156690 Thu, 25 Aug 2011 10:22:18 +0100 5156690 http://www.medworm.com/index.php?rid=5094750&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000365%2Fabstract%3Frss%3Dyes Abstract: Bordetella pertussis is the causative agent of pertussis, also called whooping cough or the cough of 100 days. Infection can result in significant morbidity and mortality, particularly in young infants. Prior to the availability of effective vaccines, pertussis was a major cause of childhood disease. With the advent of such vaccines, the incidence of disease declined dramatically into the 1970s. However, pertussis is still present, with peaks occurring every 3 to 5 years, and the number of cases has been increasing in the United States since the 1980s. With recent reports of numerous outbreaks of pertussis, there is heightened interest in the control and diagnosis of the disease. Efforts to increase immunity through vaccination and also to improve the clinical and laboratory... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5094750 Thu, 04 Aug 2011 19:08:35 +0100 5094750 http://www.medworm.com/index.php?rid=5048942&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000353%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5048942 Fri, 22 Jul 2011 00:44:34 +0100 5048942 http://www.medworm.com/index.php?rid=5048941&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000341%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5048941 Fri, 22 Jul 2011 00:44:34 +0100 5048941 http://www.medworm.com/index.php?rid=5048940&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991100033X%2Fabstract%3Frss%3Dyes We describe a 70-year-old patient with spondylodiscitis of the lumbar spine caused by Fusobacterium nucleatum. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5048940 Fri, 22 Jul 2011 00:44:34 +0100 5048940 http://www.medworm.com/index.php?rid=5048939&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000328%2Fabstract%3Frss%3Dyes Abstract: Bordetella pertussis is the causative agent of pertussis, also called whooping cough or the cough of 100 days. Infection can result in significant morbidity and mortality, particularly in young infants. Prior to the availability of effective vaccines, pertussis was a major cause of childhood disease. With the advent of such vaccines, the incidence of disease declined dramatically into the 1970s. However, pertussis is still present, with peaks occurring every 3 to 5 years, and the number of cases has been increasing in the United States since the 1980s. With recent reports of numerous outbreaks of pertussis, there is heightened interest in the control and diagnosis of the disease. Efforts to increase immunity through vaccination and also to improve the clinical and laboratory... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5048939 Fri, 22 Jul 2011 00:44:34 +0100 5048939 http://www.medworm.com/index.php?rid=5007102&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000316%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5007102 Fri, 08 Jul 2011 14:26:18 +0100 5007102 http://www.medworm.com/index.php?rid=5007101&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000304%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5007101 Fri, 08 Jul 2011 14:26:17 +0100 5007101 http://www.medworm.com/index.php?rid=5007100&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000298%2Fabstract%3Frss%3Dyes Abstract: Photorhabdus asymbiotica is a gram-negative bacillus of the family Enterobacteriaceae. The bacterium displays the curious property of bioluminescence – the production of light without heat. It is recognized as a human pathogen in the United States and Australia, where it causes both locally invasive soft tissue infection and disseminated disease. In Australia, P. asymbiotica is vectored by the soil nematode Heterorhabditis gerrardi. The vector in the U.S. has not yet been identified, but it is likely to also be a Heterorhabditid nematode. Although it grows readily on conventional culture media, clinical microbiology laboratories may misidentify this pathogenic bacterium because of an over-reliance on commercial rapid identification systems. (Source: Clinical Microbiology N... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=5007100 Fri, 08 Jul 2011 14:26:17 +0100 5007100 http://www.medworm.com/index.php?rid=4951743&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000286%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4951743 Tue, 21 Jun 2011 18:01:12 +0100 4951743 http://www.medworm.com/index.php?rid=4951742&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000274%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4951742 Tue, 21 Jun 2011 18:01:12 +0100 4951742 http://www.medworm.com/index.php?rid=4951741&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000262%2Fabstract%3Frss%3Dyes Abstract: Diagnosis of fungal infections demands skilled work with direct examination, fungal culture, and interpretation of macroscopic and microscopic features of the fungus as keystones of the diagnosis. We believe that medical mycology is often being treated in a stepmotherly fashion in the clinical microbiology laboratory. Drawing conclusions based on the fact that some diseases are considered never to occur in certain regions can be very dangerous. Migration, travel, possible modification of environmental circumstances and geo-ecological changes may all interfere with our endemic medical landscape. Lack of knowledge of “exotic” or “poverty-associated” diseases may lead to a significant delay in diagnosis. Nevertheless, fungal infections are emerging diseases, and lack of... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4951741 Tue, 21 Jun 2011 18:01:12 +0100 4951741 http://www.medworm.com/index.php?rid=4901724&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000250%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4901724 Mon, 06 Jun 2011 19:38:09 +0100 4901724 http://www.medworm.com/index.php?rid=4901723&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000249%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4901723 Mon, 06 Jun 2011 19:38:09 +0100 4901723 http://www.medworm.com/index.php?rid=4901722&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000237%2Fabstract%3Frss%3Dyes This article reviews the principles of MADLI-TOF MS and the recent literature evaluating its performance in the clinical laboratory. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4901722 Mon, 06 Jun 2011 19:38:09 +0100 4901722 http://www.medworm.com/index.php?rid=4788511&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000201%2Fabstract%3Frss%3Dyes We describe an additional case of pulmonary infection caused by M. triplex, which occurred in an immunocompetent host. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4788511 Fri, 06 May 2011 05:40:54 +0100 4788511 http://www.medworm.com/index.php?rid=4788510&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000195%2Fabstract%3Frss%3Dyes Abstract: Over the past 20 years, the number of bona fide or reputed bacterial species involved in diarrheal syndromes has increased by logarithmic proportions. Such increases have presented the clinical laboratory and microbiologist with numerous challenges in establishing an etiologic diagnosis. These challenges include the cost-effectiveness of stool cultures, searching for appropriate etiologic agents based upon medical histories and exposures, and selection of media and testing formats. Part I of this two-part review updates current issues, concepts, and approaches to establishing a laboratory diagnosis of bacterial gastroenteritis. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4788510 Fri, 06 May 2011 05:40:54 +0100 4788510 http://www.medworm.com/index.php?rid=4733149&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000183%2Fabstract%3Frss%3Dyes Abstract: Prosthetic joint infection (PJI), although a rare complication of primary or revision arthroplasty, is reported more frequently as the number patients undergoing arthroplasty increases. Accurate diagnosis of PJI is essential for adequate management and outcome. Although multiple tests have been applied, in some cases, differentiation of PJI from aseptic loosening of the prosthesis remains a challenge. Here, we review the current diagnostic laboratory modalities used for the diagnosis PJI. In Part I of this two-part article, components of the preoperative evaluation of the patient and the histology of the intraoperative evaluation were discussed. Part II of the article discusses the remaining components of the intraoperative evaluation, including periprosthetic tissue and son... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4733149 Thu, 21 Apr 2011 14:42:48 +0100 4733149 http://www.medworm.com/index.php?rid=4669796&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000171%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4669796 Sun, 03 Apr 2011 14:48:26 +0100 4669796 http://www.medworm.com/index.php?rid=4669795&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991100016X%2Fabstract%3Frss%3Dyes Listeria monocytogenes is a gram-positive, non-spore-forming, aerobic bacillus isolated from a variety of environmental sources and contaminated food products. Most cases of listeriosis appear to be foodborne. Populations at increased risk for severe or disseminated disease include neonates, the elderly, and the immunocompromised. Immune-competent people tend to experience nonspecific or gastrointestinal illness, while immune-impaired individuals often develop bacteremia, sepsis, and/or meningoencephalitis. Localized infections due to hematogenous seeding are less common (). L. monocytogenes has been recognized as an infrequently encountered agent of septic arthritis, particularly in prosthetic joint infections. This atypical presentation of an otherwise well-known pathogen highlights the ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4669795 Sun, 03 Apr 2011 14:48:26 +0100 4669795 http://www.medworm.com/index.php?rid=4669794&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000158%2Fabstract%3Frss%3Dyes Abstract: Prosthetic joint infection (PJI), although a rare complication of primary or revision arthroplasty, is reported more frequently as the number patients undergoing arthroplasty increases. Accurate diagnosis of PJI is essential for adequate management and outcome. Although multiple tests have been applied, in some cases, differentiation of PJI from aseptic loosening of the prosthesis remains a challenge. Here, we review the current diagnostic laboratory modalities used for the diagnosis PJI. In Part I of this two-part article, components of the preoperative evaluation of the patient and the histology of the intraoperative evaluation is discussed. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4669794 Sun, 03 Apr 2011 14:48:25 +0100 4669794 http://www.medworm.com/index.php?rid=4642002&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000146%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4642002 Mon, 28 Mar 2011 17:41:31 +0100 4642002 http://www.medworm.com/index.php?rid=4642001&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000134%2Fabstract%3Frss%3Dyes We present the case of a patient with pyrexia of unknown origin in whom D. maris was isolated from bone marrow. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4642001 Mon, 28 Mar 2011 17:41:31 +0100 4642001 http://www.medworm.com/index.php?rid=4642000&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000122%2Fabstract%3Frss%3Dyes This article reviews the history of malaria and its eradication in the U.S. and discusses methods for laboratory diagnosis. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4642000 Mon, 28 Mar 2011 17:41:31 +0100 4642000 http://www.medworm.com/index.php?rid=4591042&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000110%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4591042 Tue, 15 Mar 2011 00:00:00 +0100 4591042 http://www.medworm.com/index.php?rid=4591041&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000109%2Fabstract%3Frss%3Dyes Malassezia species are part of the normal human cutaneous flora, occurring mainly on the trunk and head, with the highest densities in post-pubertal adolescents (). Except for Malassezia pachydermatis, the remaining six species require an exogenous source of lipid for growth, because they are unable to synthesize C14 to C16 fatty acids (). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4591041 Tue, 15 Mar 2011 00:00:00 +0100 4591041 http://www.medworm.com/index.php?rid=4591040&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000092%2Fabstract%3Frss%3Dyes This article highlights the more common causes of food-borne illness, symptoms, diagnosis, and prevention. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4591040 Tue, 15 Mar 2011 00:00:00 +0100 4591040 http://www.medworm.com/index.php?rid=4470000&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000055%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4470000 Sun, 13 Feb 2011 01:04:22 +0100 4470000 http://www.medworm.com/index.php?rid=4469999&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000043%2Fabstract%3Frss%3Dyes Abstract: Public health laboratories perform testing to identify and characterize cases and clusters of acute gastroenteritis (AGE). Viral pathogens, in particular norovirus, are reportedly the most common cause of AGE outbreaks. CaliciNet, a centralized database at the Centers for Disease Control and Prevention, collects and compares viral sequences for surveillance and outbreak tracking purposes. At the state level, viral agent testing supports epidemiologic investigations of AGE outbreaks. The resulting data are used to educate the public health and medical communities and to track mutations that may impact testing methods. A retrospective analysis of norovirus data generated by the Virginia State Laboratory between 2001 and 2009 assessed statewide trends compared to national data.... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4469999 Sun, 13 Feb 2011 01:04:22 +0100 4469999 http://www.medworm.com/index.php?rid=4370735&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439911000031%2Fabstract%3Frss%3Dyes Echinococcosis is a parasitic tapeworm infestation caused by cestodes in the genus Echinococcus that affects both humans and other mammals, such as sheep, cattle, horses, and canines. Humans can be infected and serve as accidental intermediate hosts following the ingestion of Echinococcus eggs in food or water contaminated by feces from these infected animals (). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4370735 Wed, 19 Jan 2011 23:48:25 +0100 4370735 http://www.medworm.com/index.php?rid=4370734&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991100002X%2Fabstract%3Frss%3Dyes Abstract: Ticks require vertebrate hosts for survival and reproduction and can acquire pathogens when they ingest blood. Reservoir competency, however, varies greatly. Some rodents, such as white-footed mice (Peromyscus leucopus), are efficient reservoirs for Borrelia burgdorferi infections and infect attached larval and nymphal Ixodes scapularis ticks. Although white-tailed deer (Odocoileus virginianus) probably do not efficiently pass Lyme disease spirochetes to ticks when these ectoparasites feed, they are reservoirs for Ehrlichia chaffeensis (the agent for human monocytic ehrlichiosis). Deer are important hosts for I. scapularis and Amblyomma americanum adults, and as the number of deer has increased over the past four decades, there has been a corresponding sharp rise in abundanc... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4370734 Wed, 19 Jan 2011 23:48:25 +0100 4370734 http://www.medworm.com/index.php?rid=4293525&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000577%2Fabstract%3Frss%3Dyes Abstract: Despite the suggestions of both the Clinical and Laboratory Standards Institute (CLSI) and the American Society for Microbiology (ASM) Manual of Clinical Microbiology that hospitals should test individual patient isolates to assist in their care, periodically establish patterns of resistance for certain anaerobes, and include these data in the hospital antibiogram, anaerobic susceptibility studies are performed in only a minority of clinical laboratories and their patterns of susceptibility are obtainable mostly from published surveys conducted by a small number of research centers scattered worldwide. The Bacteroides fragilis group species, the most frequently studied anaerobes, have been reported to vary in their frequencies of resistance to all antimicrobial agents worldw... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4293525 Wed, 29 Dec 2010 04:31:09 +0100 4293525 http://www.medworm.com/index.php?rid=4219209&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000565%2Fabstract%3Frss%3Dyes (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4219209 Thu, 02 Dec 2010 07:50:20 +0100 4219209 http://www.medworm.com/index.php?rid=4219208&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000553%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4219208 Thu, 02 Dec 2010 07:50:20 +0100 4219208 http://www.medworm.com/index.php?rid=4219207&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000541%2Fabstract%3Frss%3Dyes Abstract: Parachlamydia acanthamoebae has been implicated as an emerging agent of pneumonia in humans. Recently, it has been linked to miscarriage and neonatal infections. In contrast, its role in atherosclerosis remains controversial. In animals, there is strong evidence for Parachlamydia as a new abortigenic in cattle, and further data on this agent in other animal species is accumulating. New diagnostic methods, such as specific real-time PCR and immunohistochemistry with specific anti-Parachlamydia antibodies to detect the organism within lesions, are now available to facilitate the diagnosis of parachlamydial infections in humans and animals. This review discusses parachlamydial infections in clinical settings in humans and animals, as well as their zoonotic potential and possibl... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4219207 Thu, 02 Dec 2010 07:50:19 +0100 4219207 http://www.medworm.com/index.php?rid=4167270&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991000053X%2Fabstract%3Frss%3Dyes This article reviews these newly described microorganisms and the evidence for their roles in human infections and disease. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4167270 Mon, 15 Nov 2010 23:56:50 +0100 4167270 http://www.medworm.com/index.php?rid=4124581&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000528%2Fabstract%3Frss%3Dyes The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4124581 Tue, 02 Nov 2010 00:50:07 +0100 4124581 http://www.medworm.com/index.php?rid=4124580&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000516%2Fabstract%3Frss%3Dyes This article examines the uncertainty of measurement of urine cultures and how it affects the final patient result. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4124580 Tue, 02 Nov 2010 00:50:07 +0100 4124580 http://www.medworm.com/index.php?rid=4096640&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000498%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4096640 Sun, 24 Oct 2010 12:11:13 +0100 4096640 http://www.medworm.com/index.php?rid=4096639&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000486%2Fabstract%3Frss%3Dyes Abstract: Daptomycin has been available as a gram-positive antimicrobial agent in the United States for over 6 years, and during this time there have been developments in daptomycin susceptibility testing. Daptomycin has a unique requirement for calcium; consequently, a standard calcium concentration is needed when performing in vitro testing. The calcium levels in broth and agar are presented, and with the exception of calcium-adjusted Mueller-Hinton broth, demonstrate variation between types and manufacturers. The reference methodology for daptomycin MIC testing is broth microdilution utilizing Mueller-Hinton broth with 50 μg/ml of calcium. Daptomycin is available in several commercial testing systems, which have been shown to be comparable to the reference method. Specific MICs fr... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4096639 Sun, 24 Oct 2010 12:11:13 +0100 4096639 http://www.medworm.com/index.php?rid=4030793&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000474%2Fabstract%3Frss%3Dyes The members of the genus Cryptococcus are encapsulated basidiomycetes found in soil and in the droppings of some birds, particularly pigeons (). Cryptococcosis is frequently caused by Cryptococcus neoformans and Cryptococcus gattii and, more rarely, by other Cryptococcus species, such as Cryptococcus laurentii and Cryptococcus albidus (). Although uncommon, cryptococcosis is a potentially fatal systemic fungal infection that affects humans, cats, dogs, horses, and other animals (). It is chiefly detected in animals exposed to prolonged antibiotic and anti-inflammatory therapies (). Recently, cryptococcosis dissemination has been widely reported in large, immunosuppressed dogs and those with additional incapacitating diseases (). In dogs, the central nervous system is involved in 50 to 80% ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4030793 Tue, 05 Oct 2010 14:11:50 +0100 4030793 http://www.medworm.com/index.php?rid=4030792&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000462%2Fabstract%3Frss%3Dyes Abstract: Improved methodologies, availability of genome sequences, automated technology, and commercial database systems have assisted in the transition to using molecular techniques for routine diagnostic purposes. As such, molecular species identification of bacteria by sequencing genes encoding 16S rRNA or other housekeeping functions is rapidly becoming a commonplace tool used in the clinical microbiology laboratory. These non-traditional methods are used as complementary procedures to provide definitive identification of isolates of a slow-growing or fastidious nature or those with ambiguous biochemical profiles. DNA sequencing of conserved genes and mass spectrometry applications offer great potential to assist in rapid bacterial identification and enhance our ability to discov... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=4030792 Tue, 05 Oct 2010 14:11:50 +0100 4030792 http://www.medworm.com/index.php?rid=3986565&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000450%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3986565 Tue, 21 Sep 2010 10:29:19 +0100 3986565 http://www.medworm.com/index.php?rid=3986564&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000449%2Fabstract%3Frss%3Dyes In 2008, the World Health Organization () reported that one-third of the world's population, or over 2 billion people, are infected with Mycobacterium tuberculosis. Most individuals infected with M. tuberculosis have asymptomatic disease, but an estimated 9 million people develop active tuberculosis infections each year resulting in over 2 million deaths. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3986564 Tue, 21 Sep 2010 10:29:19 +0100 3986564 http://www.medworm.com/index.php?rid=3986563&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000437%2Fabstract%3Frss%3Dyes Abstract: Hemopoietic stem cell transplantation, also known as bone marrow transplantation, is a newly developed medical procedure that is now used to treat patients who were diagnosed with diseases once thought incurable such as hematologic malignancies; immune deficiencies; solid tumors such as breast and ovarian cancers; sickle cell disease; and genetic defect disorders. To minimize the risk of donor stem cell transplant rejection, recipient patients undergo severe immunosuppression therapy as part of their care. As a consequence of the patient's profound immunosuppression, opportunistic infections emerge as common causes of disease. Part II of this article reviews some of the more common opportunistic parasitic, bacterial, and viral infections that can occur in these immunocomprom... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3986563 Tue, 21 Sep 2010 10:29:19 +0100 3986563 http://www.medworm.com/index.php?rid=3924455&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000425%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3924455 Thu, 02 Sep 2010 09:20:33 +0100 3924455 http://www.medworm.com/index.php?rid=3924454&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000413%2Fabstract%3Frss%3Dyes Abstract: Hemopoietic stem cell transplantation, often called bone marrow transplantation, is a relatively new medical procedure that is now used to treat patients who were diagnosed with diseases once thought incurable, such as hematologic malignancies, immune deficiencies, solid tumors such as breast and ovarian cancers, sickle cell disease, and genetic-defect disorders. Patients who receive bone marrow transplantation also receive severe immunosuppression therapy as part of their care to minimize the risk of donor stem cell rejection. As a consequence of the patient's profound immunosuppression, opportunistic infections emerge as common causes of disease. Part I of this article will review some of the more common opportunistic fungal infections that can occur in these immunocomprom... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3924454 Thu, 02 Sep 2010 09:20:33 +0100 3924454 http://www.medworm.com/index.php?rid=3895443&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000401%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3895443 Tue, 24 Aug 2010 09:19:56 +0100 3895443 http://www.medworm.com/index.php?rid=3895442&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000395%2Fabstract%3Frss%3Dyes Abstract: Plasmodium vivax and Plasmodium falciparum are responsible for 95% of malaria infections. P. vivax has the widest distribution and is thought to be responsible for 80% of the infections throughout the tropics, subtropics, and temperate zones. As early as 2004, a fifth malaria species had been implicated in human disease. Plasmodium knowlesi, a malaria parasite of long-tailed macaque monkeys, has been confirmed in a number of human cases from Malaysian Borneo, Thailand, Myanmar, and the Philippines. It is now well established that P. knowlesi is emerging as an important zoonotic human pathogen. Malaria is considered to be immediately life-threatening, and a patient with the diagnosis of P. falciparum or P. knowlesi malaria should be considered a medical emergency because the ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3895442 Tue, 24 Aug 2010 09:19:56 +0100 3895442 http://www.medworm.com/index.php?rid=3861642&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000358%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3861642 Sat, 31 Jul 2010 23:00:00 +0100 3861642 http://www.medworm.com/index.php?rid=3861641&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000346%2Fabstract%3Frss%3Dyes Bites from pet hamsters have been described as causing a wide variety of infections. Here, we report a case of hamster bite wound infection caused by a recently discovered species of the genus Streptococcus, Streptococcus merionis. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3861641 Sat, 31 Jul 2010 23:00:00 +0100 3861641 http://www.medworm.com/index.php?rid=3861640&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000334%2Fabstract%3Frss%3Dyes Abstract: Vaginitis is one of the most common diseases that affect women's health, with over 50% of women experiencing at least one episode of vaginal infection in their lifetime. Vaginal disease can be infectious, non-infectious, or chronic in nature. However, most cases of vaginitis are the result of infection that accounts for over 10 million physician office visits in the United States each year. Infectious vaginitis is most commonly grouped into three major categories of disease based upon microbial etiology: bacterial vaginosis, vaginal candidiasis, and vaginal trichomoniasis. Occasionally, the vulva is infected by these microorganisms, as well, and the disease is then called vulvovaginitis. Because these three infectious syndromes are caused by different groups of microorganism... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3861640 Sat, 31 Jul 2010 23:00:00 +0100 3861640 http://www.medworm.com/index.php?rid=3614067&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000279%2Fabstract%3Frss%3Dyes Abstract: Infections caused by Streptococcus suis are an important economic problem in the swine industry. Moreover, S. suis (especially serotype 2) is an agent of zoonosis that has the potential to afflict those who are in close contact with infected pigs or pork-derived products. Although sporadic cases of S. suis infections in humans have been reported during the last 40 years, a large outbreak in China emerged in 2005. The severity of the infection in humans during the outbreak, such as clinical signs of streptococcal toxic shock syndrome, attracted much attention from the scientific community and the public press. This two-part review will focus on this organism and the infections it causes, highlighting the differences between Asian and Western countries, particularly with respe... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3614067 Mon, 31 May 2010 15:11:27 +0100 3614067 http://www.medworm.com/index.php?rid=3581351&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000267%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3581351 Thu, 20 May 2010 15:14:07 +0100 3581351 http://www.medworm.com/index.php?rid=3581350&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000255%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3581350 Thu, 20 May 2010 15:14:07 +0100 3581350 http://www.medworm.com/index.php?rid=3581349&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000243%2Fabstract%3Frss%3Dyes We report a case of nosocomial bacteremia caused by S. schleiferi in a patient with cardiac insufficiency. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3581349 Thu, 20 May 2010 15:14:06 +0100 3581349 http://www.medworm.com/index.php?rid=3581348&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000231%2Fabstract%3Frss%3Dyes This report describes perhaps the first documentation of a hypermucoviscous phenotype of a UPEC strain isolated from the urine of a 54-year-old patient with chronic emphysematous pyelonephritis leading to nephrectomy of his right kidney. Culture of the patient's urine grew highly viscous colonies which rendered a “stringing” phenomenon when an inoculating needle was passed through the colonies analogous to that produced by liver-invasive strains of Klebsiella pneumoniae. Stained preparations of colony teasings emulsified in India ink and examined microscopically (×1,000) revealed two distinct halos enveloping the bacillary form. The inner halo was indicative of a capsule, while the second viscous halo enveloped the entire complex. While mucoid E. coli strains have been isolated from v... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3581348 Thu, 20 May 2010 15:14:06 +0100 3581348 http://www.medworm.com/index.php?rid=3533566&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991000022X%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3533566 Wed, 05 May 2010 15:19:32 +0100 3533566 http://www.medworm.com/index.php?rid=3533565&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000218%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3533565 Wed, 05 May 2010 15:19:32 +0100 3533565 http://www.medworm.com/index.php?rid=3533564&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000206%2Fabstract%3Frss%3Dyes We report a case of Serratia marcescens isolated from a surgical-wound infection in an immunocompromised patient with head and neck squamous-cell carcinoma. The S. marcescens isolate produced an SME-2 carbapenemase, which, despite resistance to carbapenems, remained highly susceptible to the extended-spectrum cephalosporins in vitro. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3533564 Wed, 05 May 2010 15:19:32 +0100 3533564 http://www.medworm.com/index.php?rid=3533563&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991000019X%2Fabstract%3Frss%3Dyes Abstract: Tampons have been used both to absorb blood during menstruation and as a contraceptive. In the 1980s, following deaths from toxic shock syndrome, the Food and Drug Administration (FDA) began regulating tampons as a medical device. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3533563 Wed, 05 May 2010 15:19:32 +0100 3533563 http://www.medworm.com/index.php?rid=3490242&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000188%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3490242 Wed, 21 Apr 2010 15:48:25 +0100 3490242 http://www.medworm.com/index.php?rid=3490241&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000176%2Fabstract%3Frss%3Dyes Abstract: The second edition of M35-A2 Abbreviated identification of Bacteria and Yeast contains many more identifications than the first edition, including14 species from 11 genera. Biothreat agents and agents that can be highly infectious to laboratory personnel have been added to improve rapid detection of these agents and minimize exposure of personnel to them. User-friendly tables have been included, and safety precautions are presented in detail. A summary of these improvements, as well as a review of the details for identification of the newly added species, is presented. Use of the document will allow laboratories to rapidly identify greater than 90% of the clinically important species isolated from clinical specimens without performing expensive multi-test systems or using ov... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3490241 Wed, 21 Apr 2010 15:48:25 +0100 3490241 http://www.medworm.com/index.php?rid=3432559&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000164%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3432559 Fri, 02 Apr 2010 15:30:13 +0100 3432559 http://www.medworm.com/index.php?rid=3432558&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000152%2Fabstract%3Frss%3Dyes This article discusses the current state of laboratory diagnostics and the challenges faced in using serologic assays for the diagnosis of syphilis. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3432558 Fri, 02 Apr 2010 15:30:13 +0100 3432558 http://www.medworm.com/index.php?rid=3373837&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000140%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3373837 Wed, 17 Mar 2010 16:46:17 +0100 3373837 http://www.medworm.com/index.php?rid=3373836&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000139%2Fabstract%3Frss%3Dyes (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3373836 Wed, 17 Mar 2010 16:46:17 +0100 3373836 http://www.medworm.com/index.php?rid=3373835&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000127%2Fabstract%3Frss%3Dyes Abstract: Clinical microbiologists have a new and unique opportunity to increase our value to health care by broadening how we think about disease processes and asking ourselves what we can do to help resolve a disease, assist in tracking a cause, or even predict an outbreak before it occurs. Human health, animal health (both wildlife and domestic animals), and environmental health are forever bound together. The convergence of people, animals, and the environment defines the parameters of One Health and directs attention to the impact this overlap has on public health, disease detection, and control. One Health (sometimes referred to as One Medicine) is a concept that promotes, improves, and defends the health and well-being of all species through the integration of the sciences of h... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3373835 Wed, 17 Mar 2010 16:46:17 +0100 3373835 http://www.medworm.com/index.php?rid=3349925&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000115%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3349925 Wed, 10 Mar 2010 18:03:37 +0100 3349925 http://www.medworm.com/index.php?rid=3349924&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000103%2Fabstract%3Frss%3Dyes Abstract: Bloodstream infections and sepsis are among the top causes of mortality in the United States, killing nearly 600 people per day. Many septic patients are treated in emergency medicine departments or critical care units, settings in which rapid administration of targeted antibiotic therapy drastically reduces mortality. Unfortunately, current microbiology laboratory methods are too slow to support rapid interventions, typically requiring >24 hours to detect the presence of bloodstream pathogens (hematopathogens) and at least 3 to 5 days to confirm the selection of appropriate antimicrobial therapy. Moreover, cultures from septic patients are often falsely negative due to pre-emptive therapy, the presence of fastidious organisms, or microbes that are present in low density. As... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3349924 Wed, 10 Mar 2010 18:03:37 +0100 3349924 http://www.medworm.com/index.php?rid=3279664&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000097%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3279664 Wed, 17 Feb 2010 16:40:45 +0100 3279664 http://www.medworm.com/index.php?rid=3279663&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000085%2Fabstract%3Frss%3Dyes The following describes our experience in developing an improved medium for the detection of Salmonella and Shigella species in clinical specimens. Initially, we attempted to build on past improvements of enteric plating agars containing the surfactant Niaproof 4, formerly known as Tergitol 4. However, despite their broad application for detection of Salmonella species in food safety and veterinary medical diagnostics (), Niaproof 4-supplemented (NS) enteric plating agars are limited for use on human clinical specimens because they do not adequately support the growth of Shigella species. Our goal was to develop an NS-type agar that would be sensitive for detecting Shigella as well as Salmonella species and thus be appropriate for the diagnosis of two major human bacterial enteropathogens.... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3279663 Wed, 17 Feb 2010 16:40:45 +0100 3279663 http://www.medworm.com/index.php?rid=3279662&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000073%2Fabstract%3Frss%3Dyes Abstract: Bloodstream infections are among the top causes of death in the United States, and substantial mortality is attributed to testing delays in determinating the microbial cause(s) and selection of the appropriate antibiotic. In this review, we summarize the human and financial impact of sepsis, as well as the predisposing factors, symptoms, and common modes of bacterial pathogenesis. We also detail important clinical and laboratory criteria for the diagnosis of sepsis and key aspects of the Surviving Sepsis Campaign Guidelines as they relate to diagnosis, therapy, and resuscitation from the septic event. Clinical laboratories must expand their understanding of the complexities related to diagnosing and treating sepsis in order to expand their role as productive members of inter... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3279662 Wed, 17 Feb 2010 16:40:45 +0100 3279662 http://www.medworm.com/index.php?rid=3243326&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000061%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3243326 Fri, 05 Feb 2010 16:49:22 +0100 3243326 http://www.medworm.com/index.php?rid=3243325&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643991000005X%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3243325 Fri, 05 Feb 2010 16:49:22 +0100 3243325 http://www.medworm.com/index.php?rid=3243324&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000048%2Fabstract%3Frss%3Dyes Abstract: Encephalitis is characterized by both its pleomorphic clinical presentation and its diagnostic challenges. Fever, headache, and alteration of consciousness are classically present, however, the diversity of neurological symptoms can make it difficult to distinguish encephalitis from other infectious and non-infectious central nervous system conditions. Identification of a specific pathogen has important therapeutic and prognostic implications for an individual patient and has broader public health significance in potentially identifying a need for prophylaxis of contacts or environmental control of arthropod vectors. In Part I of this article, the basic features of encephalitis and aspects of diagnostic testing for encephalitis caused by herpes simplex virus, the non-simplex... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3243324 Fri, 05 Feb 2010 16:49:22 +0100 3243324 http://www.medworm.com/index.php?rid=3193356&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000036%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3193356 Thu, 21 Jan 2010 16:28:54 +0100 3193356 http://www.medworm.com/index.php?rid=3193355&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439910000024%2Fabstract%3Frss%3Dyes Abstract: Encephalitis is characterized by both its pleomorphic clinical presentation and its diagnostic challenges. Fever, headache, and alteration of consciousness are classically present; however, the diversity of neurological symptoms can make it difficult to distinguish encephalitis from other infectious and non-infectious central nervous system conditions. Identification of a specific pathogen has important therapeutic and prognostic implications for an individual patient and has broader public health significance in potentially identifying a need for prophylaxis of contacts or environmental control of arthropod vectors. Despite the availability of nucleic acid amplification-based tests, a specific pathogen is identified in less than 50% of cases. This two-part review will focus... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3193355 Thu, 21 Jan 2010 16:28:53 +0100 3193355 http://www.medworm.com/index.php?rid=3133358&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000634%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3133358 Thu, 31 Dec 2009 16:02:48 +0100 3133358 http://www.medworm.com/index.php?rid=3133357&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000622%2Fabstract%3Frss%3Dyes Abstract: Human cytomegalovirus (CMV), a ubiquitous member of the herpesvirus family, is an important human pathogen. Infections are usually asymptomatic but can be associated with a wide spectrum of diseases, particularly in immunocompromised persons. Primary infection during pregnancy may result in congenital infection, leading to severe damage to the fetus. Intrauterine primary infections are second only to Down's syndrome as a known cause of mental retardation. CMV infection in transplant recipients may cause different clinical syndromes in different groups of patients, and the severity of the infection parallels the degree of immunosuppression. As infections are either asymptomatic or accompanied by symptoms that are not specific to CMV (such as fever and leukopenia), laborat... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3133357 Thu, 31 Dec 2009 16:02:48 +0100 3133357 http://www.medworm.com/index.php?rid=3110877&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000610%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3110877 Tue, 22 Dec 2009 16:08:02 +0100 3110877 http://www.medworm.com/index.php?rid=3110876&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000609%2Fabstract%3Frss%3Dyes In this report, we describe a patient who, after receiving a tattoo, developed M. lacunata endocarditis with cardiovascular complications, resulting in valve replacement surgery. This is the first report in Latin America of M. lacunata-induced endocarditis confirmed by sequencing of the 16s rRNA gene directly from heart valve tissue. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3110876 Tue, 22 Dec 2009 16:08:02 +0100 3110876 http://www.medworm.com/index.php?rid=3110875&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000592%2Fabstract%3Frss%3Dyes Abstract: Human cytomegalovirus (CMV), a ubiquitous member of the herpesvirus family, is an important human pathogen. Infections are usually asymptomatic but can be associated with a wide spectrum of diseases, particularly in immunocompromised persons. Primary infection during pregnancy may result in congenital infection leading to severe damage of the fetus. Intrauterine primary infections are second only to Down's syndrome as a known cause of mental retardation. CMV infection in transplant recipients may cause different clinical syndromes in different groups of patients, and the severity of the infection parallels the degree of immunosuppression. As infections are either asymptomatic or accompanied by symptoms that are not specific to CMV (such as fever and leukopenia), laborato... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3110875 Tue, 22 Dec 2009 16:08:02 +0100 3110875 http://www.medworm.com/index.php?rid=3056229&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000580%2Fabstract%3Frss%3Dyes (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3056229 Fri, 04 Dec 2009 15:59:26 +0100 3056229 http://www.medworm.com/index.php?rid=3056228&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000579%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3056228 Fri, 04 Dec 2009 15:59:26 +0100 3056228 http://www.medworm.com/index.php?rid=3056227&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000567%2Fabstract%3Frss%3Dyes This article describes the process of assay development and validation of real-time PCR and nucleic acid sequencing assays; included are descriptions of important considerations, such as the PCR workflow, inhibition testing, proper use of controls, and multiplexing. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3056227 Fri, 04 Dec 2009 15:59:26 +0100 3056227 http://www.medworm.com/index.php?rid=3029468&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000555%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3029468 Thu, 26 Nov 2009 16:22:24 +0100 3029468 http://www.medworm.com/index.php?rid=3029467&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000543%2Fabstract%3Frss%3Dyes A 60-year-old female patient who had undergone a live-donor-related, right-renal transplant 4 months previously was hospitalized with severe right-flank and leg pain of 3 months duration, accompanied by fever. Her immunosuppressive regimen included mycophenolate mofetil, tacrolimus, and prednisone. Computed tomography (CT) imaging demonstrated expansion of the right psoas muscle with central low attenuation (). Aspiration of the psoas abscess was performed for aerobic and anaerobic cultures and a Gram-stained smear (). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3029467 Thu, 26 Nov 2009 16:22:24 +0100 3029467 http://www.medworm.com/index.php?rid=3029466&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000531%2Fabstract%3Frss%3Dyes Abstract: Ljungan virus (LV), a picornavirus, was discovered in the Swedish vole population after six clustered deaths from myocarditis were noted in orienteers between 1989 and 1992. Four of five sera from the orienteer patients had detectable antibodies against one of the LV isolates. Researchers tracked data about the population density of Swedish voles carrying LV and compared them to various disease incidences in humans in northern Sweden. Both animal and human data support the possibility that LV causes or contributes to diabetes, fetal death, fetal malformations, and sudden infant death syndrome. Current research has raised the question of the importance of this newly recognized zoonotic pathogen within rodent vectors. Evidence indicates that it would be prudent to consider LV ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=3029466 Thu, 26 Nov 2009 16:22:24 +0100 3029466 http://www.medworm.com/index.php?rid=2950419&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643990900052X%2Fabstract%3Frss%3Dyes (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2950419 Mon, 02 Nov 2009 16:27:21 +0100 2950419 http://www.medworm.com/index.php?rid=2950418&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000518%2Fabstract%3Frss%3Dyes (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2950418 Mon, 02 Nov 2009 16:27:21 +0100 2950418 http://www.medworm.com/index.php?rid=2950417&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000506%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2950417 Mon, 02 Nov 2009 16:27:21 +0100 2950417 http://www.medworm.com/index.php?rid=2950416&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643990900049X%2Fabstract%3Frss%3Dyes Staphylococcus aureus is an important pathogen, and a frequent cause of community-acquired, as well as hospital-acquired, infections. The most common infections caused by S. aureus are those involving the skin and soft tissues (furuncles, cellulitis, and impetigo) and, less commonly, infections at deeper sites (bones, joints, and heart valves). Frequently, S. aureus produces toxin-mediated diseases, such as toxic shock syndrome, caused by the elaboration of toxic shock syndrome toxin 1, and food poisoning, caused by staphylococcal enterotoxins (). Another important toxin is Panton-Valentine leukocidin (PVL), which kills neutrophils. PVL production has been linked epidemiologically to specific infections, such as primary skin and soft tissue disease, severe necrotizing pneumonia, and severe... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2950416 Mon, 02 Nov 2009 16:27:20 +0100 2950416 http://www.medworm.com/index.php?rid=2950415&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000488%2Fabstract%3Frss%3Dyes This article examines seven illnesses — tuberculosis, influenza, infectious diarrhea, syphilis, bacterial pneumonia, bacterial sepsis, and malaria, and the individuals throughout history who contracted and died from them. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2950415 Mon, 02 Nov 2009 16:27:20 +0100 2950415 http://www.medworm.com/index.php?rid=2904558&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000476%2Fabstract%3Frss%3Dyes Abstract: Leisure travel by sea has existed since antiquity. Today's cruise ships serve as a gathering place for people in every age group from different countries and cultures. The closed environment aboard cruise ships, close contact among passengers and crew, and common sources of food and water provide ample opportunity for exposure to and transmission of infectious diseases. Of these, gastrointestinal and respiratory infections pose the greatest risk of outbreaks. Outbreaks on cruise ships present a public health concern, since infection is often easily spread, is difficult to control, and has the potential to disseminate pathogens. A collaborative effort between the CDC's Vessel Sanitation Program and the cruise line industry has significantly reduced the incidence of passenger ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2904558 Mon, 19 Oct 2009 15:12:31 +0100 2904558 http://www.medworm.com/index.php?rid=2803717&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000452%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2803717 Thu, 17 Sep 2009 17:59:40 +0100 2803717 http://www.medworm.com/index.php?rid=2803716&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000440%2Fabstract%3Frss%3Dyes A 26-year-old man presented with fever, malaise, scrotal skin lesions, and inguinal lymphadenopathy. An excisional biopsy specimen from an inguinal lymph node demonstrated a florid vascular proliferation. A Warthin-Starry stain, an immunoperoxidase stain, and PCR studies confirmed the presence of Bartonella henselae. The diagnosis of bacillary angiomatosis secondary to B. henselae infection was established. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2803716 Thu, 17 Sep 2009 17:59:39 +0100 2803716 http://www.medworm.com/index.php?rid=2803715&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000439%2Fabstract%3Frss%3Dyes This article reviews the performance of molecular assays for the diagnosis of common sexually transmitted infections associated with child abuse. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2803715 Thu, 17 Sep 2009 17:59:39 +0100 2803715 http://www.medworm.com/index.php?rid=2757305&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000427%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2757305 Wed, 02 Sep 2009 18:03:47 +0100 2757305 http://www.medworm.com/index.php?rid=2757304&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000415%2Fabstract%3Frss%3Dyes Abstract: Nanotechnology-based pathogen detection is an emerging technology that is poised to have a major impact on health care and medicine, food and agriculture, the environment, and biodefense. The technology bridges a variety of sciences, including biology, chemistry, physics, and statistics to create a new cadre of tools and capabilities that can be applied to basic and translational research, diagnostics, and commercialization. This burgeoning field has created an unprecedented array of technologies that have advanced detection, diagnosis, and imaging of chemical and biological agents and that offers the potential to facilitate detection of biomarkers of disease pathogenesis. This review provides a summary of the more prominent areas of nanotechnology-based pathogen detection. ... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2757304 Wed, 02 Sep 2009 18:03:47 +0100 2757304 http://www.medworm.com/index.php?rid=2719386&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000403%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2719386 Fri, 21 Aug 2009 11:41:55 +0100 2719386 http://www.medworm.com/index.php?rid=2719385&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000397%2Fabstract%3Frss%3Dyes Abstract: The Clinical Laboratory Improvement Advisory Committee (CLIAC) was mandated by the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and established in 1992 to provide advice to the Department of Health and Human Services on regulation of laboratory testing and improving laboratory quality. Since then, CLIAC has met regularly and recommended regulatory changes to CLIA, provided input on good laboratory practices, and discussed critical issues related to clinical and public health testing, the laboratory workforce, and laboratory systems research. The Committee has been effective in driving changes to microbiology quality control, which have led to a decreased burden and lower laboratory costs without sacrificing quality. The issues CLIAC addresses are complex and som... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2719385 Fri, 21 Aug 2009 11:41:55 +0100 2719385 http://www.medworm.com/index.php?rid=2674023&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000385%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2674023 Thu, 06 Aug 2009 12:24:51 +0100 2674023 http://www.medworm.com/index.php?rid=2674022&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000373%2Fabstract%3Frss%3Dyes Abstract: Mycobacterium ulcerans infection is an emerging disease that causes indolent, necrotizing skin lesions known as Buruli ulcer (BU). Approximately 10% of patients develop reactive osteitis or osteomyelitis beneath skin lesions or metastatic osteomyelitis from lymphohematogenous spread of M. ulcerans. The most plausible mode of transmission is by skin trauma at sites contaminated by M. ulcerans. Pathogenesis is mediated by a necrotizing, immunosuppressive toxin produced by M. ulcerans called mycolactone. The incidence of BU is highest in children up to 15 years old and is a public health problem in countries of endemicity due to disabling scarring and bone destruction. Today, most BU occurs in West Africa, but the disease has been reported in over 30 countries. Treatment option... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2674022 Thu, 06 Aug 2009 12:24:51 +0100 2674022 http://www.medworm.com/index.php?rid=2625578&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000361%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2625578 Wed, 22 Jul 2009 12:18:38 +0100 2625578 http://www.medworm.com/index.php?rid=2625577&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643990900035X%2Fabstract%3Frss%3Dyes Babesiosis is a well-recognized disease of veterinary importance, causing infections primarily in cattle, horses, and dogs (). The first definitive case of human babesiosis, caused by the cattle parasite Babesia divergeus, was documented in a Yugoslavian farmer in 1957 (). Even though more than 100 species of Babesia have been described, only three distinct species are recognized as important causes of human disease. In Europe, most human infections are caused by B. divergeus (), whereas in the United States, Babesia microti accounts for most infections in the Northeast () and upper Midwest (). Another Babesia sp., characterized as the WA1-type babesial parasite, is responsible for most infections on the west coast (). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2625577 Wed, 22 Jul 2009 12:18:38 +0100 2625577 http://www.medworm.com/index.php?rid=2625576&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000348%2Fabstract%3Frss%3Dyes Abstract: The genus Klebsiella (family Enterobacteriaceae), of which K. pneumoniae and K. oxytoca are the two most commonly isolated members, consists of gram-negative, non-motile, encapsulated rods. As opportunistic pathogens, Klebsiella spp. can cause a variety of illnesses including pneumonia, urinary tract infections, septicemia, soft tissue, intravenous, meningitis, liver abscess, and gastrointestinal disease, in the immunocompromised or those with underlying conditions. Current studies strongly suggest that klebsiellae, and in particular K. oxytoca, may also be associated with a variety of gastrointestinal syndromes that include antibiotic-associated hemorrhagic colitis. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2625576 Wed, 22 Jul 2009 12:18:38 +0100 2625576 http://www.medworm.com/index.php?rid=2576193&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000336%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2576193 Tue, 07 Jul 2009 12:09:58 +0100 2576193 http://www.medworm.com/index.php?rid=2576192&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000324%2Fabstract%3Frss%3Dyes We present the case of a previously healthy, 28-year-old male with listerial rhomboencephalitis (brainstem meningoencephalitis). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2576192 Tue, 07 Jul 2009 12:09:58 +0100 2576192 http://www.medworm.com/index.php?rid=2576191&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000312%2Fabstract%3Frss%3Dyes Abstract: After reading the popular novel, “The Cobra Event,” then U.S. President Bill Clinton, concerned with the prospect of use of a biologic agent against the United States, issued Presidential Directive 39. This executive act resulted in the formation of the Laboratory Response Network (LRN), a structured consortium of clinical, governmental, and public health laboratories. The LRN became operational in August 1999, and though few in the laboratory field noticed its birth, by the fall of 2001 and the anthrax letter events, the alliance of clinical and public health laboratories was becoming a reality. The LRN provided the framework for much closer cooperation between clinical (sentinel) laboratories and their public health counterparts and set the stage for a cooperative appr... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2576191 Tue, 07 Jul 2009 12:09:58 +0100 2576191 http://www.medworm.com/index.php?rid=2505872&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000300%2Fabstract%3Frss%3Dyes The genus Dysgonomonas was recently created by Hofstad et al. () to accommodate a group of fastidious gram-negative, facultative anaerobic, coccobacillus-shaped organisms. This genus constitutes a phylogenetic cluster within the Bacteroides-Prevotella-Porphyromonas group. Three species are included in the genus. Dysgonomonas gadei was first isolated from an infected human gall bladder (). Dysgonomonas capnocytophagoides has been recovered from stool samples, primarily in immunocompromised patients or those with severe underlying diseases (), and from blood and wound and abscess specimens (). This species includes organisms formerly designated CDC group DF-3 (). Dysgonomonas mossii has been described recently by Lawson et al. (). It was isolated from abdominal drainage from a 68-year-old wo... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2505872 Thu, 25 Jun 2009 08:55:48 +0100 2505872 http://www.medworm.com/index.php?rid=2505871&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000294%2Fabstract%3Frss%3Dyes Abstract: The Clinical and Laboratory Standards Institute (CLSI) is a global, nonprofit, membership-driven organization dedicated to developing standards and guidelines for the health care and medical testing community. CLSI's mission is to develop best practices in clinical and laboratory testing and to promote their use throughout the world, using a consensus-driven process that balances the viewpoints of industry, government, and the health care professions. CLSI recognizes that health is the most important foreign policy issue of our time. In response to the call for laboratory capacity building, and on behalf of the U.S. President's Emergency Plan for AIDS Relief, CLSI has developed the Global Health Partnerships (GHP) program. Working collaboratively, the GHP program is improvin... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2505871 Thu, 25 Jun 2009 08:55:48 +0100 2505871 http://www.medworm.com/index.php?rid=2456787&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000282%2Fabstract%3Frss%3Dyes The editors of Clinical Microbiology Newsletter extend an invitation to authors who may wish to contribute an article or editorial for publication in CMN. Of special interest are timely topics of interest to clinical microbiologists and infectious disease physicians. Persons with suggestions for articles or editorials should contact the Editor listed to the right to discuss the details of their potential submission. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2456787 Sat, 06 Jun 2009 01:49:37 +0100 2456787 http://www.medworm.com/index.php?rid=2456786&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000270%2Fabstract%3Frss%3Dyes Streptococcus pneumoniae is a well-recognized human pathogen, particularly in patients in the pediatric age group. Most pediatric pneumococcal infections are localized in the respiratory tract; however, more serious, but less common, disseminated infections are well documented (). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2456786 Sat, 06 Jun 2009 01:49:36 +0100 2456786 http://www.medworm.com/index.php?rid=2456785&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000269%2Fabstract%3Frss%3Dyes Abstract: Bacteria of the genus Bacillus are widely distributed in nature, useful in agriculture and industry, and occasionally directly harmful to humans. The uniqueness of Bacillus relates to its ability to produce spores that can survive desiccation, heat, and cold and can germinate readily. The toxins that cause anthrax and food poisoning are encoded by plasmid-borne genes, allowing different species to have strikingly similar chromosomal DNA despite radically different phenotypes. Bacillus infections are uncommon and often associated with trauma or foreign bodies. Food poisoning caused by Bacillus spp. is much less common than other forms of bacterial food poisoning and almost always brief and self-limited. Treatment of Bacillus infections is usually straightforward once the spec... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2456785 Sat, 06 Jun 2009 01:49:33 +0100 2456785 http://www.medworm.com/index.php?rid=2423181&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000257%2Fabstract%3Frss%3Dyes An 80-year-old man visited his primary care physician with the complaint of an intermittent cough for 2 to 3 years, which had become worse in the past few months. The patient was producing clear mucus with no blood. The cough was thought to be due to gastroesophageal reflux disease. The patient had a history of smoking but had quit 25 years previously and also reported a history of exposure to asbestos when he served as an electrician in the British Navy. Born and raised in England, the patient lived for 30 years in northern California and in the San Jose area. He then moved to Salem, Oregon, where he has lived for the past 19 years. He is an avid gardener with 5 acres of land on which he grows ornamental trees, such as oak and Japanese maples. The patient had no family history of pulmonar... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2423181 Wed, 20 May 2009 06:04:23 +0100 2423181 http://www.medworm.com/index.php?rid=2423180&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000245%2Fabstract%3Frss%3Dyes This article explores the ways that ASM helps clinical microbiologists. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2423180 Wed, 20 May 2009 06:04:13 +0100 2423180 http://www.medworm.com/index.php?rid=2387501&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000233%2Fabstract%3Frss%3Dyes This article examines these and new emerging infections. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2387501 Mon, 04 May 2009 20:56:55 +0100 2387501 http://www.medworm.com/index.php?rid=2346892&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000221%2Fabstract%3Frss%3Dyes If your laboratory has isolated an uncommon organism, a common organism from an unusual patient, or an organism that presented a particular diagnostic challenge, why not share the information with your colleagues through the Clinical Microbiology Newsletter. The editors would like to receive interesting case reports from our readers for possible publication in the Newsletter. Submitted case reports should contain (i) a brief clinical history summarizing the symptoms and course of the illness, (ii) a description of how the organism(s) was cultured and differentiated from closely associated organisms, and (iii) the results of susceptibility tests for the isolate(s). (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2346892 Mon, 20 Apr 2009 22:52:26 +0100 2346892 http://www.medworm.com/index.php?rid=2346891&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS019643990900021X%2Fabstract%3Frss%3Dyes Wayne, Pennsylvania, USA, June 2008 — The enormous global problem of tuberculosis (with roughly one-third of the world's population infected with Mycobacterium tuberculosis), coupled with an increasing incidence of infections caused by nontuberculous mycobacteria, presents unique challenges for the laboratory diagnosis of mycobacterial infections. The diagnosis of M. tuberculosis needs to be optimized and expedited for good patient management, and appropriate control measures need to be implemented to prevent transmission of tuberculosis. There are similar demands for accurate identification of the ever-increasing numbers of species of nontuberculous mycobacteria. (Source: Clinical Microbiology Newsletter) Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2346891 Mon, 20 Apr 2009 22:52:24 +0100 2346891 http://www.medworm.com/index.php?rid=2346890&cid=s_38450_77_f&fid=38450&url=http%3A%2F%2Fwww.cmnewsletter.com%2Farticle%2FPIIS0196439909000208%2Fabstract%3Frss%3Dyes Abstract: Numerous cases of donor-derived infections (DDI) after solid-organ transplantation have been reported in recent times. While some are expected (often due to cytomegalovirus or Epstein-Barr virus), others have been clinically unexpected. Pre-transplant screening is quite helpful in abrogating the risks of DDI but could be optimized further to increase patient safety, reduce risk, augment the number of organs transplanted, and save more lives. Testing thus far has largely been serologic; advances in testing technology have allowed the use of nucleic acid testing, as well as other new testing modalities. The optimal use of such testing in the solid organ transplant setting remains to be determined. Increased awareness of DDI has augmented and will continue to augment our abilit... Clinical Microbiology Newsletter news http://www.medworm.com/rss/comments.php?id=2346890 Mon, 20 Apr 2009 22:52:22 +0100 2346890