MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Clinical Neurology and Neurosurgery' source. Tue, 07 Feb 2012 03:15:40 +0100 http://www.medworm.com/index.php?rid=5644790&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846712000546%2Fabstract%3Frss%3Dyes (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644790 Wed, 01 Feb 2012 04:34:18 +0100 5644790 http://www.medworm.com/index.php?rid=5534880&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002289%2Fabstract%3Frss%3Dyes Primary central nervous system lymphoma (PCNSL) is a rare malignant extranodal non-Hodgkin lymphoma (NHL) whose incidence has increased in both immunocompromised and immunocompetent patients. At present it receives a special attention in neuro-oncology and accounts for 4% of all intracranial tumors . Most of PCNSL are diffuse large B-cell lymphomas and have relative dismal survival results compared with extracerebral diffuse large B-cell lymphomas. Local relapse remains an important concern in PCNSL surveillance. Usually, the tumor is confined to the central nervous system (CNS), including the brain, leptomeninges and spinal cord. Other rare places include retina, vitreous humor, optic nerve, etc. Distal metastases are seldom encountered due to less than 1% of individuals with PCNSL had be... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534880 Fri, 23 Dec 2011 21:05:35 +0100 5534880 http://www.medworm.com/index.php?rid=5534877&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002198%2Fabstract%3Frss%3Dyes We described two epileptic male patients which experienced erectile dysfunction during Topiramate treatment. Serum sexual hormones were tested during treatment and at several time intervals following drug discontinuation. Topiramate did not seem to affect plasma levels of total, free and bioavailable testosterone and sex hormone-binding globulin. Since Topiramate erectile dysfunctions could not be related to changes in reproductive hormones levels, a vasogenic mechanism must be considered. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534877 Fri, 23 Dec 2011 21:05:35 +0100 5534877 http://www.medworm.com/index.php?rid=5534860&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711004124%2Fabstract%3Frss%3Dyes (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534860 Fri, 23 Dec 2011 21:05:34 +0100 5534860 http://www.medworm.com/index.php?rid=5644791&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003623%2Fabstract%3Frss%3Dyes Abstract: In multiple sclerosis, neuropathic pain is a frequent condition, negatively influencing the overall quality of life. Cranial neuralgias, including trigeminal, glossopharyngeal neuralgias, as well as occipital neuralgia, are typical expression of neuropathic pain. Neuralgias are characterised by paroxysmal painful attacks of electric shock-like sensation, occurring spontaneously or evoked by innocuous stimuli in specific trigger areas. In multiple sclerosis, demyelination in the centrally myelinated part of the cranial nerve roots plays an important role in the origin of neuralgic pain. These painful syndromes arising in multiple sclerosis are therefore considered “symptomatic”, in contrast to classic cranial neuralgias, in which no cause other than a neurovascular contact is ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644791 Wed, 30 Nov 2011 05:00:00 +0100 5644791 http://www.medworm.com/index.php?rid=5644807&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003143%2Fabstract%3Frss%3Dyes Reports on tumours originating from trigeminal nerve/Cavum Meckelii (CM) are scarce. Such neoplasms represent less than 0.5% of histologically proved intracranial tumours; among them approximately one-third are trigeminal schwannomas with the remainder consisting of meningiomas, lipomas, and epidermoid tumours . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644807 Mon, 21 Nov 2011 05:00:00 +0100 5644807 http://www.medworm.com/index.php?rid=5405090&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003283%2Fabstract%3Frss%3Dyes (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405090 Mon, 14 Nov 2011 19:25:33 +0100 5405090 http://www.medworm.com/index.php?rid=5644809&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003118%2Fabstract%3Frss%3Dyes Giant cell tumor (GCT) is uncommon bone tumor, and the skull involvement in this tumor is very rare . This tumor frequently shows locally aggressive behavior , and a relatively high recurrence rate . Resection is the preferred treatment for GCTs of the skull, and the outcome correlated the extent of resection . However, considering the limitation in surgical extent of skull base tumors, high recurrence rates, adjuvant treatments, and management for recurrence seem to be important issues in GCTs. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644809 Mon, 14 Nov 2011 05:00:00 +0100 5644809 http://www.medworm.com/index.php?rid=5644808&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100312X%2Fabstract%3Frss%3Dyes Central neurocytomas (CN) comprise only 0.25–0.5% of brain tumors. They mainly located in lateral ventricles. CN generally occur in young adults with a favorable prognosis and benign biologic behavior. Primary occurrence of CN in fourth ventricle has been reported very rarely. Only 5 case reports are available in the literature (). The WHO classification considers central neurocytomas as grade II tumors. The proliferative index is usually low, except for the rare “atypical” variants. “Atypical” histological features include high proliferative activity, vascular proliferation, and necrosis . We herein report an interesting case of atypical neurocytoma which was present in fourth ventricle with extensive hemorrhage occurred during surgery. (Source: Clinical Neurology and Neurosurge... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644808 Wed, 09 Nov 2011 05:00:00 +0100 5644808 http://www.medworm.com/index.php?rid=5644806&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003155%2Fabstract%3Frss%3Dyes The approach to a patient presenting with multiple cranial neuropathies is complex given the diverse number of causes including neoplastic, vascular, traumatic, infectious, autoimmune and inflammatory etiologies. In cases where imaging reveals thickened dura with enhancement around multiple cranial nerves and no primary cause can be found, the diagnosis of idiopathic hypertrophic pachymeningitis (IHP) is given . Here we present the case of a patient with multiple worsening cranial neuropathies who underwent extensive evaluation consistent with neurosarcoidosis, but whose dural biopsy revealed IHP. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644806 Wed, 09 Nov 2011 05:00:00 +0100 5644806 http://www.medworm.com/index.php?rid=5644810&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003167%2Fabstract%3Frss%3Dyes Conclusions: Our experience, with the largest reported single-surgeon series of patients harboring CIMs, favors early resection, especially in patients with neurologic deficit. Resection may also be a prudent first-line strategy for patients with larger thoracic masses (≥13mm) regardless of neurologic status. Neurologic deficits engendered by CIM usually improve after resection and the majority of patients in our series would have still elected to have an intrathecal pump for pain control knowing a CIM would have developed. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644810 Mon, 07 Nov 2011 05:00:00 +0100 5644810 http://www.medworm.com/index.php?rid=5644804&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003040%2Fabstract%3Frss%3Dyes Abstract: Tanycytic ependymoma is an uncommon but well-recognized variant of ependymoma. Here we report a case of tanycytic ependymoma occurring at the region of filum terminale in a 44-year male who presented with low backache, bilateral lower limb weakness and urinary incontinence. MR imaging in this patient showed a lesion that was composed of solid and cystic components and was suggestive of ependymoma. The filum terminale region is an extremely unusual location for the occurrence of tanycytic ependymoma. To the best of our knowledge this is the third case of tanycytic ependymoma occurring in the filum terminale region. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644804 Mon, 07 Nov 2011 05:00:00 +0100 5644804 http://www.medworm.com/index.php?rid=5644799&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003088%2Fabstract%3Frss%3Dyes The objective of this study was to retrospectively review the surgical results following gross total resection and partial resection with or without radiotherapy for craniopharyngiomas and analyze the related factors of surgical results.Methods: From 1994 to 2009, 214 patients underwent 219 procedures for craniopharyngiomas. We retrospectively reviewed the pre- and postoperative data of patients, reported the perioperative and long-term surgical results and analyzed the influencing factors and the relationship between hypothalamic involvement and postoperative quality of life.Results: Gross total resection was achieved in 154 procedures (70.3%). Perioperative mortality was 5%. Perioperative hyperpyrexia was the most significant risk factor for perioperative mortality. A total of 151 patien... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644799 Mon, 07 Nov 2011 05:00:00 +0100 5644799 http://www.medworm.com/index.php?rid=5534861&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003179%2Fabstract%3Frss%3Dyes Abstract: Brain metastasis is the most common intracranial tumor in adults. Currently, treatment of brain metastasis requires multidisciplinary approach tailored for each individual patient. Surgery has an indispensible role in relieving intracranial mass effect, improving neurological status and survival while providing or confirming neuropathological diagnosis with low mortality and morbidity rates. Besides the resection of a single brain metastasis in patients with accessible lesions, good functional status, and absent/controlled extracranial disease; surgery is proven to play a role in management of multiple metastases. Surgical technique has an impact on the outcome since piecemeal resection rather than en bloc resection and leaving infiltrative zone behind around resection cavity may... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534861 Wed, 02 Nov 2011 04:00:00 +0100 5534861 http://www.medworm.com/index.php?rid=5644811&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003106%2Fabstract%3Frss%3Dyes Shunt overdrainage leading to subdural hematoma (SDH) formation is known to be one of the major complications of ventriculoperitoneal (V-P) shunt implantation . Shunt overdrainage after mild head trauma is rare. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644811 Mon, 31 Oct 2011 04:00:00 +0100 5644811 http://www.medworm.com/index.php?rid=5644805&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003052%2Fabstract%3Frss%3Dyes Since McLean and Donahue discovered the Powassan virus in 1958, there have been approximately 34 cases of confirmed infection. This is the first case report to describe a serologically confirmed example of Powassan viral hemorrhagic encephalitis, which involved lesions of the bilateral thalami. MRI images of the patient's central nervous system (CNS) were unique, and when such images are encountered in the clinical setting, Powassan viral infection should be considered. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644805 Mon, 31 Oct 2011 04:00:00 +0100 5644805 http://www.medworm.com/index.php?rid=5644798&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100309X%2Fabstract%3Frss%3Dyes Conclusion: The modified Lund concept, directed at bedside real-time monitoring of brain biochemistry by CM showed better results compared to CPP-targeted therapy in the treatment of comatose patients sustaining SBI after aneurysmal SAH and severe TBI. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644798 Mon, 31 Oct 2011 04:00:00 +0100 5644798 http://www.medworm.com/index.php?rid=5644794&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003039%2Fabstract%3Frss%3Dyes Conclusions: C. pneumoniae antibody positivity was independently associated with ischemic stroke in elderly patients and its presence does not alter the stroke outcome. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644794 Wed, 26 Oct 2011 04:00:00 +0100 5644794 http://www.medworm.com/index.php?rid=5644803&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002952%2Fabstract%3Frss%3Dyes Over 90% of malignant melanomas of the spine are metastatic. Rarely, however, a primary malignant melanoma may originate from the spine. In this setting, an intramedullary location is common. The remaining malignant melanomas in this region originate from the spinal cord or leptomeninges, which surround the nerve roots. The diagnosis is confirmed immunohistologically, as it is difficult to distinguish a malignant melanoma from melanotic schwannoma and meningeal melanocytoma . Total excision of a spinal malignant melanoma can have a better course with adjuvant radiotherapy and chemotherapy . This case report presents a patient who underwent surgery in 2007 and the pathological diagnosis was a primary spinal malignant melanoma originating from a nerve root. Despite metastasis, the patient wa... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644803 Mon, 24 Oct 2011 04:00:00 +0100 5644803 http://www.medworm.com/index.php?rid=5644797&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003003%2Fabstract%3Frss%3Dyes Conclusion: We can conclude that brain MRI, fMRI and MRS studies performed in patients with externalised SCS can be safely executed. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644797 Mon, 24 Oct 2011 04:00:00 +0100 5644797 http://www.medworm.com/index.php?rid=5644796&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003015%2Fabstract%3Frss%3Dyes Conclusion: The three neuropsychological tests used in the Eu-iNPH are expedient, highly diagnostically discriminative, and well suited to evaluate changes following shunt treatment. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644796 Mon, 24 Oct 2011 04:00:00 +0100 5644796 http://www.medworm.com/index.php?rid=5644795&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711003027%2Fabstract%3Frss%3Dyes Conclusions: This study expanded the spectrum of the MPZ mutations and revealed two disparate mechanisms of MPZ mutations associated with a typical CMT1B phenotype. Other modifying genetic, epigenetic, or environmental factors on CMT1B may exist to explain the discrepancy between the cellular phenotypes. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644795 Mon, 24 Oct 2011 04:00:00 +0100 5644795 http://www.medworm.com/index.php?rid=5644793&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002939%2Fabstract%3Frss%3Dyes Conclusions: IC is rare (the present cases account for 0.23% of all retrieved cases). Its chief clinical manifestations include headache, nasal obstruction, polydipsia and polyuria, and visual disorder. Lesions include solid, cystic, and mixed cystic and solid types. It is very difficult to resect the whole diseased region because this disease invades the cranial base, nasal sinuses and nasopharynx. Individualized treatments should be used according to lesion characteristics and invasion range, for example, stereotaxic interstitial brachytherapy. Radical resection or partial resection plus external beam radiation therapy produces better prognosis in IC than intracranial craniopharyngioma. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644793 Mon, 24 Oct 2011 04:00:00 +0100 5644793 http://www.medworm.com/index.php?rid=5534881&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002290%2Fabstract%3Frss%3Dyes We report a case of acute intrathecal baclofen overdose occurring after refilling of the implanted pump. We also present the clinical and electroencephalographic features of such overdose and discuss the risk of iatrogenic overdose by manipulating implanted pumps. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534881 Wed, 19 Oct 2011 04:00:00 +0100 5534881 http://www.medworm.com/index.php?rid=5534864&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002216%2Fabstract%3Frss%3Dyes Conclusion: The results of this study are in line with previous observations, and imply that the presence of LESCL is associated with the presence of NMO-IgG and thus an indicator of NMO. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534864 Wed, 19 Oct 2011 04:00:00 +0100 5534864 http://www.medworm.com/index.php?rid=5644802&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002794%2Fabstract%3Frss%3Dyes Abstract: A 68-year-old right-handed woman with no history of brain damage or familial left-handedness was admitted to our hospital due to the acute onset of speech difficulty; her speech was nonfluent. Literal and phonological paraphasias, agrammatism and paragrammatism were observed. Brain MRI revealed an acute infarction in the right anterior cerebral artery territory, involving the right corpus callosum. Moreover, cerebral blood flow was decreased not only in the area of the right corpus callosum but also in the left fronto-temporal lobe, suggesting crossed diaschisis. This is a rare case of crossed aphasia following an infarction in the right corpus callosum. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644802 Mon, 17 Oct 2011 04:00:00 +0100 5644802 http://www.medworm.com/index.php?rid=5644792&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002940%2Fabstract%3Frss%3Dyes Abstract: Background: Carotid endarterectomy (CEA) is one of the most commonly performed and studied surgical procedures for extracranial ischemic disease.Objective: The authors reviewed the outcome of 39 consecutive carotid endarterectomy procedures performed by a single surgeon with emphasis on the safety of discharging patients the same day of the procedure.Methods: Retrospective analysis was performed over a two-year period on patients who were admitted as outpatients and underwent CEA. Following CEA, patients were observed for 4–6h in the recovery room and Duplex ultrasonography was completed to assess the endarterectomy repair. Determination was then made whether patients could be safely discharged home.Results: Over a two year period, CEA was performed 39 times in 37 outpatients. ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644792 Fri, 14 Oct 2011 04:00:00 +0100 5644792 http://www.medworm.com/index.php?rid=5534885&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002733%2Fabstract%3Frss%3Dyes We are very interested in Chi Kyung Kim and coworkers’ study addressing the findings of elevated leukocyte count independently associated with moderate-to-severe cerebral white matter lesions (WMLs) . However, Dr. Kim's study did not yield similar finding of high sensitivity C-reactive protein (hs-CRP) associated with WMLs as the Rotterdam Scan Study did in 2005 . Between these two studies mentioned above, in addition to difference in age as the author pointed out in the article, we are also concerned about the contrary findings in Dr. Kim's study. First, different criteria for assigning subjects to separate groups are used in these two studies. Dr. Kim chose to use visual Fazekas rate scale for WMLs classification, resulting in one moderate-to-severe group with early confluent foci (B) ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534885 Fri, 14 Oct 2011 04:00:00 +0100 5534885 http://www.medworm.com/index.php?rid=5534884&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002757%2Fabstract%3Frss%3Dyes Tumors of the orbital apex can present in a variety of ways based on the complexity of the neurovascular anatomy in this region. The differential diagnosis of lesions in this region range from benign, slow-growing lesions such as cavernous hemangioma, schwannoma, pseudotumor, and fibrous dysplasia to more aggressive, and fast-growing lesions such as lymphoma, sarcoma, and metastasis. Symptoms from optic nerve compression and a lack of clinical diagnosis prompt surgical management. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534884 Fri, 14 Oct 2011 04:00:00 +0100 5534884 http://www.medworm.com/index.php?rid=5644801&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002782%2Fabstract%3Frss%3Dyes We describe a patient who presented with a “polio-like” syndrome with brachial diplegia caused by neuroborreliosis. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644801 Thu, 13 Oct 2011 04:00:00 +0100 5644801 http://www.medworm.com/index.php?rid=5534883&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002769%2Fabstract%3Frss%3Dyes Proatlantal intersegmental artery is a persistent carotid–vertebral embryonic anastomosis. This artery is very rare, and 2 types have been described, proatlantal artery types I and II. Persistent primitive proatlantal intersegmental artery (proatlantal artery type I) arises from the internal carotid artery and transverses rostrally to enter the foramen magnum where it joins the vertebral artery. Persistent primitive first cervical intersegmental artery (proatlantal artery type II) arises from the external carotid artery, runs posteriorly to join the vertebral artery and then passes through the transverse foramen of the C1 vertebra segment. The purpose of this paper is to present a case with proatlantal artery type II without an ipsilateral vertebral artery. This anomaly was an incidental... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534883 Wed, 05 Oct 2011 04:00:00 +0100 5534883 http://www.medworm.com/index.php?rid=5534882&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002770%2Fabstract%3Frss%3Dyes We present two complicated cases, who presented SVS after CPS. Only a few cases with SVS after CPS have been reported . Through the eventful treatment course of the two cases, we want to discuss what may be the rational treatment choice for this syndrome. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534882 Wed, 05 Oct 2011 04:00:00 +0100 5534882 http://www.medworm.com/index.php?rid=5282588&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002174%2Fabstract%3Frss%3Dyes Conclusion: The establishment of neonatal screening should be a priority to avoid cases of mentally retardation. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282588 Tue, 04 Oct 2011 21:25:50 +0100 5282588 http://www.medworm.com/index.php?rid=5282587&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002162%2Fabstract%3Frss%3Dyes Abstract: Worldwide stroke incidence seems to decrease in high income countries but to largely increase in low and middle countries. The mean age of stroke onset also seems to be gradually increasing in many developed countries, which is consistent with the third epidemiological transition in the world, being characterized by a delay in age at onset of chronic disease. This review in neurological progress provides an overview of mean age at onset of stroke from worldwide stoke incidence studies and has noted that a lack of incidence studies presenting mean age of stroke onset over years from the developing world may result in a delay of prevention strategies for its people's well-being at the population level in the 21st century. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282587 Tue, 04 Oct 2011 21:25:50 +0100 5282587 http://www.medworm.com/index.php?rid=5282583&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002253%2Fabstract%3Frss%3Dyes Conclusion: CNS SFT is a rare lesion. Six percent of lesions are malignant. GTR is superior to STR although the degree of superiority is not clear. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282583 Tue, 04 Oct 2011 21:25:50 +0100 5282583 http://www.medworm.com/index.php?rid=5282582&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002824%2Fabstract%3Frss%3Dyes (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282582 Tue, 04 Oct 2011 21:25:50 +0100 5282582 http://www.medworm.com/index.php?rid=5534868&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100271X%2Fabstract%3Frss%3Dyes Abstract: The extent of resection in high grade glioma is increasingly been shown to positively effect survival. Nevertheless, heterogeneity and migratory behavior of glioma cells make gross total resection very challenging. Several techniques were used in order to improve the detection of residual tumor. Aim of this study was to analyze advantages and limitations of fluorescence and image guided resection. A multicentric prospective study was designed to evaluate the accuracy of each method. Furthermore, the role of 5-aminolevulinc acid and neuronavigation were reviewed.Twenty-three patients harboring suspected high grade glioma, amenable to complete resection, were enrolled. Fluorescence and image guides were used to perform surgery. Multiple samples were obtained from the resection cavi... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534868 Mon, 03 Oct 2011 04:00:00 +0100 5534868 http://www.medworm.com/index.php?rid=5534867&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002721%2Fabstract%3Frss%3Dyes Conclusion: Training reduces weight-bearing dissymmetry and improves movement selectivity. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534867 Mon, 03 Oct 2011 04:00:00 +0100 5534867 http://www.medworm.com/index.php?rid=5405091&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002745%2Fabstract%3Frss%3Dyes Conclusions: MIBG scintigraphy is an accurate test for PD detection and differential diagnosis between PD and MSA; this method shows high sensitivity and adequate specificity in this field. Nevertheless, possible causes of false negative and false positive findings should be considered when interpreting the scintigraphic results. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405091 Mon, 03 Oct 2011 04:00:00 +0100 5405091 http://www.medworm.com/index.php?rid=5644800&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002708%2Fabstract%3Frss%3Dyes We report a patient of parakinesia brachialis oscitans after acute infarction involving the right motor cortex and frontal subcortex. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5644800 Wed, 28 Sep 2011 04:00:00 +0100 5644800 http://www.medworm.com/index.php?rid=5534866&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002691%2Fabstract%3Frss%3Dyes Abstract: Objectives: Depression has been consistently reported in people with epilepsy. Several studies also suggest a higher burden of cardiovascular diseases. We therefore analysed psychosocial co-morbidity and cardiovascular risk factors in patients with a lifetime history of epilepsy in the PsyCoLaus study, a Swiss urban population-based assessment of mental health and cardiovascular risk factors in adults aged between 35 and 66 years.Patients and methods: Among 3719 participants in the PsyCoLaus study, we retrospectively identified those reporting at least 2 unprovoked seizures, defined as epilepsy. These subjects were compared to all others regarding psychiatric, social, and cardiovascular risk factors data using uni- and multivariable assessments.Results: A significant higher need ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534866 Wed, 28 Sep 2011 04:00:00 +0100 5534866 http://www.medworm.com/index.php?rid=5534865&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002460%2Fabstract%3Frss%3Dyes Conclusions: In order to improve stroke treatment it is necessary to harness the use of the 112 emergency line and include primary care in the stroke assistance chain. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534865 Mon, 26 Sep 2011 04:00:00 +0100 5534865 http://www.medworm.com/index.php?rid=5534875&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002150%2Fabstract%3Frss%3Dyes Abstract: Muslin wrapping is a commonly utilized alternative technique in the treatment of aneurysms that are not amenable to direct clipping. In this case report, we describe two patients from different institutions who both required aneurysm wrapping with gauze/muslin for aneurysm reinforcement. Both patients developed an inflammatory foreign body response to muslin visible on MRI that resulted in a vasculitic stenosis. The onset of TIAs was at 6 months and 1 month postoperatively, respectively. The stenoses rapidly progressed to near occlusion despite antiplatelet therapy, and in one case, an aggressive corticosteroid regimen. One patient eventually developed leptomeningeal collateral flow that allowed tolerance of the stenosis, while the other patient required microsurgical bypass. The... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534875 Thu, 22 Sep 2011 04:00:00 +0100 5534875 http://www.medworm.com/index.php?rid=5282610&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100268X%2Fabstract%3Frss%3Dyes Posterior reversible encephalopathy syndrome (PRES), is a clinical entity characterized by headache, nausea, vomiting, seizures, conscious disturbance, and visual disorder associated with neuroradiological findings, predominantly white matter abnormalities of the parieto-occipital lobes . It has been recognized in a wide range of conditions, including hypertensive encephalopathy, organ transplantation, uremia, preeclampsia/eclampsia, connective tissue diseases, systemic lupus erythematosus, thrombotic thrombocytopenic purpura, cerebral angiograms, hypertension-inducing treatments such as erythropoietin, blood transfusions, or immunosuppressive therapy particularly with cyclosporine A and tacrolimus, and immunoglobulin, as well as various chemotherapeutic agents such as cisplatin . (Source:... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282610 Mon, 19 Sep 2011 04:00:00 +0100 5282610 http://www.medworm.com/index.php?rid=5534878&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002228%2Fabstract%3Frss%3Dyes Abstract: Epithelioid solitary fibrous tumor (SFT) has recently been reported and is an extremely rare soft-tissue neoplasm. Herein we present an epithelioid SFT attached to the falx cerebri occurring in a Chinese woman. This patient underwent gross-total tumor resection at the age of 30 years and recurred 68 months following the initial total resection. Histologically, the initial lesion exhibited features of classic spindle cell SFT. In contrast, the recurrent tumor demonstrated exclusively epithelioid morphology with significant atypia. Both the original and recurrent lesions showed positivity for vimentin, CD34, Bcl-2, and CD99, whereas were negative for all the remaining antibodies. The epithelioid feature in SFT seems to be associated with a more aggressive clinical behavior in this ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534878 Mon, 12 Sep 2011 04:00:00 +0100 5534878 http://www.medworm.com/index.php?rid=5282609&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002629%2Fabstract%3Frss%3Dyes Spontaneous intracranial hypotension (SIH) is a clinical syndrome in which there is symptomatic absolute or relative hypovolemia of the cerebrospinal fluid (CSF) . This syndrome can present with various neurological symptoms, with some reports of unusual manifestation of tremor, chorea and coma . The pathophysiology of this neural dysfunction is explained by cerebral venous dilation and downward displacement of the brain, with distortions of the cranial nerves and traction of pain-sensitive structures . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282609 Mon, 12 Sep 2011 04:00:00 +0100 5282609 http://www.medworm.com/index.php?rid=5282608&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002630%2Fabstract%3Frss%3Dyes Saccular aneurysms are frequently associated with arteriovenous malformations (AVMs) probably due to hemodynamic stresses exerted on an arterial wall. The incidence of such an association has been reported between 5.5% and 12% . Most of these aneurysms are small or medium sized, giant aneurysms are very rare with only few cases published. Some of the associated aneurysms located on the arterial feeders of the AVM may decrease in size or even disappear completely after the AVM treatment . However, intranidal aneurysms usually venous in origin, require treatment and when treated microsurgically, they should be removed together with the AVM nidus. If the intranidal aneurysm is giant (≥25mm), the complete removal of the AVM becomes even more challenging. Microscope integrated near-infrared i... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282608 Mon, 12 Sep 2011 04:00:00 +0100 5282608 http://www.medworm.com/index.php?rid=5282599&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002332%2Fabstract%3Frss%3Dyes Reversible posterior leucoencephalopathy syndrome (RPLS) typically presents with global encephalopathy, seizures, headache and visual symptoms and is often triggered by a hypertensive emergency. Neuroimaging shows reversible vasogenic subcortical edema without infarction, preferentially of the posterior brain regions. In some patients, the RPLS lesions have a very asymmetrical and even unilateral distribution . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282599 Mon, 12 Sep 2011 04:00:00 +0100 5282599 http://www.medworm.com/index.php?rid=5282607&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002599%2Fabstract%3Frss%3Dyes A 22-year-old man presented to the emergency department with intermittent headaches after striking his head on a car door due to decreased peripheral vision. Upon questioning, he related a 6 month history of weakness as well as a decrease in libido and beard growth. There was no family history of pituitary or endocrine neoplasia. Physical findings included bitemporal hemianopsia, optic atrophy, galactorrhea, and testicular atrophy. MRI of the pituitary revealed a 5.8×3.7×3.0cm sellar/suprasellar mass extending into the cavernous sinus, the right lateral ventricle with associated lateral horn dilatation, and the left sphenoid and ethmoidal sinuses (A). Laboratory investigations revealed an extremely elevated prolactin level of 5474μg/L, hypogonadotrophic hypogonadism, low IGF-1 levels, l... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282607 Fri, 09 Sep 2011 04:00:00 +0100 5282607 http://www.medworm.com/index.php?rid=5282603&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002393%2Fabstract%3Frss%3Dyes Radiation necrosis is the most significant complication associated with Gamma Knife radiosurgery. It typically becomes manifest as a necrotic white matter lesion 3 or more months following treatment . Treatment volume and radiation dose are the two most important predictors of radiation necrosis. Once radiation necrosis has become clinically apparent treatment has historically been limited to corticosteroids. Antiplatelet agents, anticoagulants and hyperbaric oxygen have been studied but there is currently minimal high quality evidence to support their use in routine clinical practice . If the radiation necrosis fails to respond to steroid treatment therapeutic options are limited. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282603 Fri, 09 Sep 2011 04:00:00 +0100 5282603 http://www.medworm.com/index.php?rid=5282602&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100240X%2Fabstract%3Frss%3Dyes Werner syndrome (WS) is a rare autosomal recessive disorder, caused by a variety of functional mutations in the WRN gene located at 8p (8p11-12) . WS patients appear to grow and develop normally until adolescence, after which signs and symptoms begin to appear by their early 20s. These include premature graying and loss of hair; bilateral ocular cataracts; type 2 diabetes mellitus; osteoporosis; various forms of arteriosclerosis and hypogonadism. WS patients have a higher risk of certain cancers . Meningioma is the most frequent benign neoplasm in Werner syndrome . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282602 Fri, 09 Sep 2011 04:00:00 +0100 5282602 http://www.medworm.com/index.php?rid=5282600&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002447%2Fabstract%3Frss%3Dyes Conclusion: Phrenic neuropathy is a rare but important complication of diabetes mellitus. We report the first case of the beneficial use of intravenous immunoglobulin in diabetic phrenic neuropathy. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282600 Fri, 09 Sep 2011 04:00:00 +0100 5282600 http://www.medworm.com/index.php?rid=5282593&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002459%2Fabstract%3Frss%3Dyes Conclusions: SCA can receive a high dose of irradiation during radiosurgical treatment for CTN. This study does not confirm any vascular damage to the SCA after radiosurgery for CTN. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282593 Fri, 09 Sep 2011 04:00:00 +0100 5282593 http://www.medworm.com/index.php?rid=5282601&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002411%2Fabstract%3Frss%3Dyes Herpes simplex virus (HSV) is a common cause of encephalitis, but localized brainstem invasion is rare . The olfactory and trigeminal nerves are the suggested sites of viral entry. Some unaffected olfactory bulbs in cases of fatal HSV encephalitis and few cases of HSV brainstem encephalitis suggest the trigeminal route . The tropism of HSV in the temporal lobe after trigeminal inoculation in an experimental model has also suggested the same route. However, although axonal transmission has been shown in animals, there have not been any reported human cases of viral spreading via a neural connection. Herein, we report a case of HSV brainstem encephalitis with axonal propagation of the virus. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282601 Wed, 07 Sep 2011 04:00:00 +0100 5282601 http://www.medworm.com/index.php?rid=5282595&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002423%2Fabstract%3Frss%3Dyes Abstract: Objective: To determine the safety and efficacy of combined local mild hypothermia and IV rtPA in treating acute ischemic stroke (AIS) patients with MRI perfusion- and diffusion-weighted imaging (PWI/DWI) mismatch within a 6-h stroke window.Methods: AIS patients within 6h of a minimum 20% PWI/DWI MRI mismatch were randomly assigned to 3 groups: local mild hypothermia with IV rtPA (Group A); IV rtPA (Group B); or conventional anti-platelet aggregation (Group C). Mortality and National Institutes of Health Stroke Scale (NIHSS) and the modified Rankin Scale (mRS) score and Barthel Index (BI) were used in evaluation.Results: There were significant differences in NIHSS 24h after treatment among the three groups (P (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282595 Wed, 07 Sep 2011 04:00:00 +0100 5282595 http://www.medworm.com/index.php?rid=5282606&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002356%2Fabstract%3Frss%3Dyes We present the case of an 18-year-old boy, who was treated by risperidon (up to 8mg/day) and clonazepam (up to 4mg/day) combination because of schizophrenia since the age of 16. Due to an acute psychotic episode up to 5mg/day haloperidol was introduced as an add-on therapy to risperidon resulting in acute oculogyric symptoms in July, 2009. After a usage of 16 days, the haloperidol medication was completely stopped, whereas biperiden (2mg tid) was introduced. Subsequently, risperidon was also replaced by olanzapine (10mg/day). However, severe segmental dystonia developed with the combination of retrocollis, toricollis and oculofacial dyskinesia in September, 2009. Because brain MRI was negative and Wilson's disease, DYT-1 positive dystonia or acoruloplasminemia could not be diagnosed in the... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282606 Mon, 05 Sep 2011 04:00:00 +0100 5282606 http://www.medworm.com/index.php?rid=5282604&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002381%2Fabstract%3Frss%3Dyes Nodular fasciitis is a benign, usually self-limiting myofibroblastic proliferation arising from the fascia. It typically involves the upper extremities (48%) and trunk (20%), but may occur anywhere . Peripheral neuropathy induced by nodular fasciitis is unusual, and case reports requiring surgical treatment due to symptoms are also extremely rare. Here, we present a rare case of nodular fasciitis associated with cubital tunnel syndrome. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282604 Mon, 05 Sep 2011 04:00:00 +0100 5282604 http://www.medworm.com/index.php?rid=5282594&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002435%2Fabstract%3Frss%3Dyes In this study, 63 (31.5%) of patients were 55 years or younger. Both age groups had comparable RF profiles, but smoking emerged as an independent predictor for SVD at a younger age (OR 2.9; 95% CI 1.5–5.5; p=0.002). Younger patients had better functional (OR 1.8; 95% CI 1.3–2.5; p=0.0001) and cognitive (χ2 13.94; p=0.0009) status compared to older patients. However, two thirds of younger patients had some degree of cognitive deficit. Total score on ARWMC scale was lower in younger patients (mean 12.3 in younger versus 15.2 in older, OR 1.11; 95% CI 1.0–1.18; p=0.001). There was a strong correlation in both groups between functional score, cognitive status and ARWMC score (p (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282594 Mon, 05 Sep 2011 04:00:00 +0100 5282594 http://www.medworm.com/index.php?rid=5282589&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002265%2Fabstract%3Frss%3Dyes Conclusions: iMRI-guided transsphenoidal pituitary surgery provides the surgeon with immediate radiographic feedback during the procedure and aides in overcoming the limitations in direct visualization during such procedures. As a result of this it may enable surgeons to perform such procedures with fewer complications and increased rate of gross total resection. However, the impact of this technology on long-term tumor control still needs to be determined with further follow-up. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282589 Mon, 05 Sep 2011 04:00:00 +0100 5282589 http://www.medworm.com/index.php?rid=5534879&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002277%2Fabstract%3Frss%3Dyes Inflammatory myofibroblastic tumors (IMFTs) are a clinically and histologically heterogeneous group of inflammatory lesions of unknown aetiology, which are most commonly described in the lungs, but have been described in most organs including: ovary, pancreas, liver, stomach, kidney, bladder, thyroid, orbit, breast, and central nervous system . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534879 Fri, 02 Sep 2011 04:00:00 +0100 5534879 http://www.medworm.com/index.php?rid=5282611&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002368%2Fabstract%3Frss%3Dyes We read with interest the article “Hemorrhagic leukoencephalitis linked to Epstein-Barr virus in an adult patient” by P. Befort, N. Gaillard, C. Roubille, and A. Le Quellec AL, published in Clinical Neurology and Neurosurgery 112 (2010) 829–831. The authors reported a rare case of hemorrhagic leukoencephalitis linked to Epstein-Barr virus (EBV) in an adult patient, who was successfully treated with intravenous corticotherapy and acyclovir. We would like to comment on this rare and interesting case. We also previously reported a case of hemorrhagic leukoencephalitis accompanied by EBV in an adult patient . An initial brain magnetic resonance imaging (MRI) showed a focal lesion in the right temporal lobe. Viral encephalitis was suspected. Despite treatment with intravenous acyclovir, M... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282611 Fri, 02 Sep 2011 04:00:00 +0100 5282611 http://www.medworm.com/index.php?rid=5282605&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100237X%2Fabstract%3Frss%3Dyes Baclofen, a derivate of Gamma-amino butyric acid (GABA), is a muscle relaxant used for treatment of the spasticity in different neuromuscular disorders like multiple sclerosis, cerebral palsy and spinal cord injuries. This GABA agonist elicits amelioration of motor movement and thereby improves spastic symptoms. Intrathecal baclofen administration is an alternative to oral therapy, which is limited by relative higher side effects and less bioavailability as intrathecal therapy . In addition, the intrathecal therapy is more effective due to direct application of baclofen into the cerebrospinal fluid. Baclofen pump implantation for continuous intrathecal application is a well known treatment option. Baclofen overdose or withdrawal can be dangerous complications caused by either dysfunction o... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282605 Fri, 02 Sep 2011 04:00:00 +0100 5282605 http://www.medworm.com/index.php?rid=5282592&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002344%2Fabstract%3Frss%3Dyes Conclusion: In LGGs, extent of removal associated with tumor progression. The pathology of astrocytoma, especially gemistocytic astrocytoma, was an independent prognostic factor for recurrence and malignant transformation. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282592 Fri, 02 Sep 2011 04:00:00 +0100 5282592 http://www.medworm.com/index.php?rid=5282598&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002320%2Fabstract%3Frss%3Dyes We report a patient experiencing sudden onset isolated GA, providing unique insights into its clinical and neuroanatomical correlates. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282598 Thu, 01 Sep 2011 04:00:00 +0100 5282598 http://www.medworm.com/index.php?rid=5282597&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100223X%2Fabstract%3Frss%3Dyes A variant of Guillain–Barré syndrome (GBS) with acute exclusively motor neuropathy, early conduction block (CB), normal or brisk tendon reflexes and fast recovery has been recently described in China and also in Western countries . The term “acute motor axonal neuropathy” (AMAN) has been coined because some clinical, electrophysiological and laboratory findings matched the features of the multifocal motor neuropathy. AMAN is often associated with anti GM1 and anti-GD1a IgG antibodies and a preceding Campylobacter jejuni infection. Little is known about pathological changes in the central nervous system (CNS) in patients with GBS. We performed nerve conduction studies (NCS) and central motor conduction studies by means of transcranial magnetic stimulation (TMS) in a patient who was c... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282597 Thu, 01 Sep 2011 04:00:00 +0100 5282597 http://www.medworm.com/index.php?rid=5282596&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002241%2Fabstract%3Frss%3Dyes Conclusion: An overlap between the two forms of split cord malformation does exist. The role of meninx primitiva in the formation of median bony septum is debatable. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282596 Thu, 01 Sep 2011 04:00:00 +0100 5282596 http://www.medworm.com/index.php?rid=5174302&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001405%2Fabstract%3Frss%3Dyes Abstract: Objective: Both valproic acid and levetiracetam are anti-epileptic drugs, often used either alone or in combination. The present study compares valproate (VPA) with levetiracetam (LEV) as an intravenous (i.v.) anticonvulsant treatment in intensive care patients suffering from aneurysmal subarachnoid hemorrhage (aSAH) with a high risk of seizures.Patients and methods: A prospective, single-center patient registry of 35 intensive care unit (ICU) patients with onset seizure and/or high risk of seizures underwent an anticonvulsive, first-line single treatment regimen either with VPA or LEV. Plasma concentrations (pc), interactions between drugs in the ICU context, adverse effects and seizure occurrences were observed and recorded.Results: A significant decrease in the pc in patients ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174302 Tue, 30 Aug 2011 04:21:34 +0100 5174302 http://www.medworm.com/index.php?rid=5174296&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001338%2Fabstract%3Frss%3Dyes Abstract: Background: Clinical outcome of Chinese relapsing remitting multiple sclerosis (RRMS) patients is uncertain.Aim: To study the long-term clinical outcome of Chinese RRMS patients.Method: RRMS patients with duration of 10 years or longer followed up in our hospital is retrospectively studied.Results: 61 RRMS patients (75% female) were studied. Their mean symptom onset age was 25.9 years and mean duration was 20.6 years (range 10–33); 36% patients had received β-interferon and 30% azathioprine. Their mean EDSS scores were 3.3 (range 1–7) and 4.7 (range 1–8) at 10 years and latest follow-up (mean duration 20.6 years) respectively. At 10 years, 30% patients had EDSS score ≤2, 34% EDSS 2.5–3.5, 20% EDSS 4.0–5.5 and 16% ≥6; 18% developed SPMS. At latest follow-up, 15% pat... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174296 Tue, 30 Aug 2011 04:21:32 +0100 5174296 http://www.medworm.com/index.php?rid=5174293&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002496%2Fabstract%3Frss%3Dyes (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174293 Tue, 30 Aug 2011 04:21:32 +0100 5174293 http://www.medworm.com/index.php?rid=5534876&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002204%2Fabstract%3Frss%3Dyes We report two Japanese patients with lateral medullary infarction who presented with vertigo, vomiting, nystagmus, and unilateral loss of temperature sensation as the initial signs before MRI of the brain demonstrated hyperintensity in the lateral part of medulla oblongata. The unilateral disturbance of temperature sensation could be easily detected by a cotton swab soaked in alcoholic solution. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534876 Fri, 26 Aug 2011 04:00:00 +0100 5534876 http://www.medworm.com/index.php?rid=5534874&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002149%2Fabstract%3Frss%3Dyes We report a case of action dystonia, or task-specific dystonia, appearing in the leg only while going down stairs. Two similar cases of focal task-specific dystonia have been reported by Lo and Frucht . The dystonia in our case was highly responsive to a low dose of an anticonvulsant and positron emission tomography (PET) showed hypoactivity in a circuit of the basal ganglia in the patient. We discuss the nosological link between the dystonia in our case and paroxysmal kinesigenic dyskinesia (PKD) . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534874 Fri, 26 Aug 2011 04:00:00 +0100 5534874 http://www.medworm.com/index.php?rid=5534873&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002101%2Fabstract%3Frss%3Dyes We present a case to illustrate our use of the hydrogel dural sealant DuraSeal (Confluent Surgical, Waltham, MA) to anchor paddle leads during spinal cord stimulation revision surgery. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534873 Fri, 26 Aug 2011 04:00:00 +0100 5534873 http://www.medworm.com/index.php?rid=5534872&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001880%2Fabstract%3Frss%3Dyes Malformations of cortical development (MCD) form a group of disorders of the brain, which primarily affect development of the cerebral cortex. They commonly present with developmental delay, mental retardation, and epilepsy. Heterotopia are clusters of neurons and glia that form a nodule of gray matter in an inappropriate location . Polymicrogyria (PMG), on the other hand, is a cortical malformation characterized by numerous aberrant microgyri separated by shallow sulci with fusion of adjacent molecular layers, with excessive folding and abnormal cytoarchitecture. On brain imaging studies, PMG appears as thickened and irregular cortex with variably visible microgyri . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534872 Fri, 26 Aug 2011 04:00:00 +0100 5534872 http://www.medworm.com/index.php?rid=5534871&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001892%2Fabstract%3Frss%3Dyes Cerebellopontine angle (CPA) is a rare site for tumor metastasis, usually manifested with rapidly progressive neurological deficits involving cranial nerves V, VII, VIII and IX–XI, etc. . Although surgical intervention is beneficial to control the metastatic lesion and halt neurological deterioration, it poses significant risks in causing further neurological sequela. Therefore, early diagnosis as well as careful monitoring of the neurological functions is essential to manage the metastatic CPA lesions. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534871 Fri, 26 Aug 2011 04:00:00 +0100 5534871 http://www.medworm.com/index.php?rid=5534870&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001855%2Fabstract%3Frss%3Dyes Wilson's disease (WD) is an autosomal recessive disorder of copper metabolism due to the dysfunction of a copper transporting P-type ATPase (ATP7B), which leads to copper accumulation mainly in the liver, brain, cornea and kidney . MRI studies in Wilson's disease (WD) show frequent involvementof putamen, ventral thalamus, caudate head, globus pallidus, midbrain, pons, and cerebellum . The lesions generally appeared hyperintense on T2-weighted images and hypointense on T1-weighted images. These signal abnormalities were thought to reflect neuronal loss, gliosis, degeneration of fibers, and vacuolization associated with increased water content in the brain. Of the MRI abnormalities seen in patients with WD, the low signals in T2-weighted images and conventional gradient echo sequences (T2*-w... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534870 Fri, 26 Aug 2011 04:00:00 +0100 5534870 http://www.medworm.com/index.php?rid=5534869&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001867%2Fabstract%3Frss%3Dyes We present two young adult patients operated for this type of lesion who show no signs of recurrence 2 years after surgery. These tumours have a bimodal peak of presentation: most occur in young patients under 25 years, and the rest present in the elderly. Characteristically they show both Antoni A and Antoni B areas, intense inmunoreactivity to S-100 and Vimentin protein, and none to EMA or CD34. Electron microscopy is diagnostic when basal membrane is found around the cytoplasmatic processes. MRI spectroscopy depicts increased myoinositol, choline and lipids, and perfusion MR demonstrates high rCBV with a characteristic curve due to the total absence of blood brain barrier. An origin in the Schwann cells of the perivascular nervous plexus in the subarachnoid space is the most accepted th... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534869 Fri, 26 Aug 2011 04:00:00 +0100 5534869 http://www.medworm.com/index.php?rid=5534863&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002186%2Fabstract%3Frss%3Dyes Conclusions: Matrix coils were most likely to need retreatment. Retreatment rates were comparable for bare platinum and HydroCoils. Follow-up angiography demonstrated statistically significant attenuation of residual aneurysms for HydroCoils. Matrix group had the greatest and HydroCoils the least tendency to recanalize. Factors other than coil surface-coating may attenuate aneurysm recurrence. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534863 Fri, 26 Aug 2011 04:00:00 +0100 5534863 http://www.medworm.com/index.php?rid=5534862&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002125%2Fabstract%3Frss%3Dyes Conclusions: Although there currently is better understanding, diagnostic imaging and treatment of sciatica, a strong similarity in narrative type between the two stories was observed. Literary narratives can reflect every day practice, and probably can also be used to give better insight in dealing with diseases. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5534862 Fri, 26 Aug 2011 04:00:00 +0100 5534862 http://www.medworm.com/index.php?rid=5405117&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001909%2Fabstract%3Frss%3Dyes Cavernous hemangiomas (also known as cavernous malformations, cavernous angiomas, or cavernomas) account for 8–15% of intracranial vascular malformations . Histologically, they consist of sinusoidal vascular caverns lined by a single layer of endothelium and separated by fibrous stroma. There are no tight junctions. Mature vascular structures, smooth muscle (pericytes), elastin, and intervening brain tissue are absent while thrombus of varying ages is common . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405117 Fri, 26 Aug 2011 04:00:00 +0100 5405117 http://www.medworm.com/index.php?rid=5405116&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001818%2Fabstract%3Frss%3Dyes Periventricular heterotopia is a disorder in neuronal migration where newly born neurons fail to migrate from their birthplace along the lining of the lateral ventricles of the brain, resulting in the characteristic ectopically placed neuronal nodules . One of the most common presentations is seizure disorder. There are no uniform guidelines for the management of heterotopia-based seizure disorder. However, treatment generally follows standard guidelines involving focal epilepsies. Surgical resection can be offered for patients with intractable seizures. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405116 Fri, 26 Aug 2011 04:00:00 +0100 5405116 http://www.medworm.com/index.php?rid=5405115&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100182X%2Fabstract%3Frss%3Dyes Haemangiopericytoma is an uncommon neoplasm arising from Zimmerman pericytes around capillaries and postcapillary venules, usually located in the musculoskeletal system and the skin. Primary meningeal haemangiopericytoma is not common and constitutes less than 1% of all intracranial tumours. Although stereotactic radiosurgery is known as a useful treatment option for recurred or remnant intracranial haemangiopericytoma, due to its difficulty of diagnosis prior to tissue confirmation, there has been no report regarding radiosurgery as the primary treatment option for haemangiopericytoma. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405115 Fri, 26 Aug 2011 04:00:00 +0100 5405115 http://www.medworm.com/index.php?rid=5405114&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001831%2Fabstract%3Frss%3Dyes Acute cerebellitis is an inflammatory syndrome which can occur as either a primary infectious, para or post infectious disorder. Infectious pathogens that have been reported to be causal or associated with acute cerebellitis include varicella, measles, mumps, rubella, Epstein-Barr virus, cytomegalovirus, herpes simplex virus, influenza virus, parainfluenza virus, poliovirus, coxsackie virus, salmonella typhi, Borrelia burgdorferi, Coxiela burnetii, bordetella pertussis and mycoplasma pneumoniae . The incidence of acute cerebellitis is unknown and the literature has consisted primarily of a collection of case reports. Acute cerebellitis may also occur without evidence of preceding or concurrent infection . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405114 Fri, 26 Aug 2011 04:00:00 +0100 5405114 http://www.medworm.com/index.php?rid=5405113&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001788%2Fabstract%3Frss%3Dyes We report the case of a patient with an acute onset of aphasia and right-sided hemiparesis, in which a P-CT scan revealed regional hyperperfusion and further diagnostic supported an epileptic origin. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405113 Fri, 26 Aug 2011 04:00:00 +0100 5405113 http://www.medworm.com/index.php?rid=5405112&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001715%2Fabstract%3Frss%3Dyes Chemical salts of lithium are used for treatment of mood disorders, such as bipolar affective disorder. Neurotoxicity with lithium therapy is well recognised and reported as a potential risk for patients treated with the drug. Neuropathy and radiculopathy are rare presentations of lithium related neurotoxicity . It is important to recognise neuropathy early in patients treated with lithium, as it is potentially reversible when the drug is withdrawn. Furthermore, symptoms of neuropathy may herald further toxic effects. Acute systemic illnesses such as diarrhoea may precipitate changes in lithium metabolism that may trigger these events. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405112 Fri, 26 Aug 2011 04:00:00 +0100 5405112 http://www.medworm.com/index.php?rid=5405111&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001703%2Fabstract%3Frss%3Dyes Conclusions: Temporal lobe pleomorphic xanthoastrocytomas causing chronic intractable epilepsy occur in younger patients, and demonstrate excellent long-term results in seizure improvement and tumor control with surgery. We support the choice between simple lesionectomy and a tailored resection with amygdalohippocampectomy guided by preoperative findings, intraoperative electrocorticography, and the severity and chronicity of the patient's epilepsy. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405111 Fri, 26 Aug 2011 04:00:00 +0100 5405111 http://www.medworm.com/index.php?rid=5405110&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100165X%2Fabstract%3Frss%3Dyes We report our experience with expandable cylindrical cages in order to reconstruct and to stabilize cervical spine with metastasis. Between June 2004 and January 2006, a consecutive series of six patients underwent to resection of metastatic tumor in the cervical spine followed by expandable cylindrical cage reconstruction of the anterior vertebral column. All patients achieved immediate stability with neurological preservation. There were no significant complications related to the expandable cages in a mean follow up period of 10.5 months.Expandable cylindrical cages are effective resources for functional reconstruction after tumor resection in patients with cervical metastasis with advantages in the quality of life. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405110 Fri, 26 Aug 2011 04:00:00 +0100 5405110 http://www.medworm.com/index.php?rid=5405109&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001363%2Fabstract%3Frss%3Dyes We present a case report of a patient with a bilateral paramedian thalamic infarct in which a polysomnographic evaluation of sleep was performed four days and five months after stroke. In the acute phase, polysomnography showed an impairment of phase 2 NREM and absence of phase 3 and 4 NREM with absent sleep spindles. After the acute stroke phase, hypersomnolence improved and sleep spindles reappeared as well as phase 3 and 4 of NREM sleep.Our patient clear clinical and polysomnographic improvement makes us suppose that in this case the initial impairment could have been essentially due to a functional transitory impairment of the thalamocortical and corticothalamic connections.This case report is peculiar because it discloses a marked improvement of sleep architecture which to the best of... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405109 Fri, 26 Aug 2011 04:00:00 +0100 5405109 http://www.medworm.com/index.php?rid=5405108&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001375%2Fabstract%3Frss%3Dyes We present here the case of a 45-year-old HIV positive male who presented to our emergency room on two separate occasions with slurring of speech and difficulty walking. Neurological examination was significant for bilateral up going plantars, symmetrically brisk deep tendon reflexes, bilateral ankle and patellar clonus with a clear sensorium. These signs initiated a major work-up to rule out causes of bulbar and spinal cord dysfunction which were all non-contributory. On his second admission he admitted to sniffing and inhaling Maximum Impact (ethyl chloride). His neurological syndrome resolved rapidly after discontinuation of exposure. Our case highlights the fact that inhalant abuse is increasing and inhalants like ethyl chloride may present with a neurological syndrome comprising non-l... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405108 Fri, 26 Aug 2011 04:00:00 +0100 5405108 http://www.medworm.com/index.php?rid=5405107&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001387%2Fabstract%3Frss%3Dyes Auditory brainstem implantation (ABI) is indicated in case of bilateral neural deafness. The majority of the patients suffers from bilateral vestibular schwannomas related to neurofibromatosis type 2 . Common other indications for ABI are bilateral severe ossification of the cochlea due to otosclerosis, cochlear obliteration due to meningitis, cochlear aplasia and traumatic cochlear nerve avulsion . ABI can also be considered in case of bilateral vestibulocochlear neuropathy in patients with craniofacial hyperostotic disorders, such as Camurati-Engelmann disease, sclerosteosis, osteopetrosis and craniometaphyseal dysplasia. Hyperostosis Cranialis Interna (HCI) is such a hyperostotic hereditary disease characterised by endosteal hyperostosis and osteosclerosis of the cranium and the skull b... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405107 Fri, 26 Aug 2011 04:00:00 +0100 5405107 http://www.medworm.com/index.php?rid=5405106&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001429%2Fabstract%3Frss%3Dyes We report a patient with middle cerebral artery dissection who developed a large middle cerebral artery dissecting aneurysm mimicking a hemorrhagic stroke. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405106 Fri, 26 Aug 2011 04:00:00 +0100 5405106 http://www.medworm.com/index.php?rid=5405105&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001430%2Fabstract%3Frss%3Dyes Ballism is a relatively rare hyperkinetic movement disorder with a very low incidence at about 1 in 500,000 in the general population . It is characterised by irregular, wide amplitude, vigorous, poorly patterned movements of the limbs, primarily due to activity of the proximal limb and associated axial muscles . The movements are usually continuous but may be intermittent and can be voluntarily suppressed by the patient, although only for a few minutes. They are most prominent during periods of rest but are absent during sleep. In some patients, the movements are so severe that they lead to physical exhaustion or injury of the affected limb from striking bedrails and walls . Ballism can occur in association with other types of involuntary movements, such as dystonia, myoclonus, or orofaci... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405105 Fri, 26 Aug 2011 04:00:00 +0100 5405105 http://www.medworm.com/index.php?rid=5405104&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002095%2Fabstract%3Frss%3Dyes The objective of the study is to evaluate whether patients presenting with acute, spontaneous intracerebral hemorrhage (ICH) benefit from prescription of prophylactic antiepileptic drug (PAED).Method: All patients with a discharge diagnosis of acute, spontaneous ICH admitted to our institution in the calendar years 2004 and 2007 were included. We retrospectively reviewed the records for baseline characteristics, hospital course, PAED use, early seizures, length of stay, discharge disposition, and death.Results: 157 patients met our criteria for review. 46 (29%) patients were placed on a PAED. 12 (7.6%) had early seizures. 11% of patients placed on a PAED had an early seizure versus 6.3% who not placed on a PAED. Death or hospice discharge was less common in patients prescribed a PAED, whil... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405104 Fri, 26 Aug 2011 04:00:00 +0100 5405104 http://www.medworm.com/index.php?rid=5405103&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001776%2Fabstract%3Frss%3Dyes Conclusions: Virtual reality technology can accurately simulate the anatomical feature of the temporal bridging veins which facilitates the planning of individual operations in neurosurgery. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405103 Fri, 26 Aug 2011 04:00:00 +0100 5405103 http://www.medworm.com/index.php?rid=5405102&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001843%2Fabstract%3Frss%3Dyes Conclusions: The screening questionnaire for PD is a reliable and valid instrument. The predictive performance of the simplified questionnaire is as good as the original. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405102 Fri, 26 Aug 2011 04:00:00 +0100 5405102 http://www.medworm.com/index.php?rid=5405101&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100179X%2Fabstract%3Frss%3Dyes Conclusion: Previous studies have shown good patients’ acceptance for awake craniotomy, but only a few times using formal approaches. By utilizing a formal questionnaire we could verify good patient acceptance for awake craniotomy for the treatment of brain tumors in or close to eloquent areas. This is a novel approach that substantiates previously published experiences. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405101 Fri, 26 Aug 2011 04:00:00 +0100 5405101 http://www.medworm.com/index.php?rid=5405100&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001806%2Fabstract%3Frss%3Dyes Abstract: Objective: To obtain information on functional integrity of the facial nerve by transcranial electrical motor evoked potentials independent of nerve visualization and to improve prediction of postoperative function.Patients and methods: In a prospective clinical study, 68 patients with cerebello-pontine angle tumors and 5 patients with trigeminal neuralgia were investigated by facial motor evoked potentials (FMEP) elicited by multi-pulse transcranial electrical motor cortex stimulation. For recording the same electrode set-up was used as for continuous EMG monitoring of the orbicularis oculi and oris muscles. Pre-surgical FMEP amplitudes and latencies were correlated with tumor extensions. End to start amplitude ratios were compared to early and long-term facial nerve function by... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405100 Fri, 26 Aug 2011 04:00:00 +0100 5405100 http://www.medworm.com/index.php?rid=5405099&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001740%2Fabstract%3Frss%3Dyes Conclusions: Despite the symmetry found between the right and left sides, the values of the main anatomic parameters involved in the localization of the LCN presented a great degree of variability. Even so, dissection using the proposed anatomical triangle allows for the localization of the LCN in almost all cases. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405099 Fri, 26 Aug 2011 04:00:00 +0100 5405099 http://www.medworm.com/index.php?rid=5405098&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001752%2Fabstract%3Frss%3Dyes Abstract: Objective: To analyse postoperative pain due to osteoarthritis in patients with Parkinson's disease submitted to bilateral subthalamic nucleus stimulation.Methods: Fifty-three parkinsonian patients (mean age, 59.9±8.3 years; mean disease duration, 11.5±4.2 years) referred for subthalamic nucleus stimulation were enrolled. Patients were prospectively asked to refer and describe any pain due to osteoarthritis they experienced at any time during the preoperative period and within the 6 postoperative months. Pre-existing pain due to osteoarthritis, therapeutic changes, parkinsonian motor disability and weight gain were assessed as explanatory factors for occurrence pain due to osteoarthritis after surgery.Results: After surgery, thirty patients (57%) complained of pain due to osteo... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405098 Fri, 26 Aug 2011 04:00:00 +0100 5405098 http://www.medworm.com/index.php?rid=5405097&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001764%2Fabstract%3Frss%3Dyes Conclusion: In bilateral hyperostotic sphenoorbital meningiomas we propose staged surgery when clinical and radiological progression is observed. Subtotal tumor resection with the aim of optic nerve decompression and subsequent orbital reconstruction provides satisfactory results. The most affected eye should be treated first. In case of additional cavernous sinus infiltration, focal radiation therapy can be considered. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405097 Fri, 26 Aug 2011 04:00:00 +0100 5405097 http://www.medworm.com/index.php?rid=5405096&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001739%2Fabstract%3Frss%3Dyes Conclusion: Alfarol capsule can be used as an external skin marker. Our simple and inexpensive method is a useful addition to preoperative evaluation of superficial intracranial lesions. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405096 Fri, 26 Aug 2011 04:00:00 +0100 5405096 http://www.medworm.com/index.php?rid=5405095&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001727%2Fabstract%3Frss%3Dyes Conclusion: In the presence of alternative methods of therapy, microvascular decompression operations should be performed with low risk to the patient. There is a learning curve involved with this operation and the surgeon should remain always critical of his/her performance and aspire for a “perfect” result. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405095 Fri, 26 Aug 2011 04:00:00 +0100 5405095 http://www.medworm.com/index.php?rid=5405094&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001661%2Fabstract%3Frss%3Dyes Conclusions: Peripapillary RNFL measurements correlated with the clinical appearance of the optic discs, suggesting that OCT may assist in the follow up of IIH patients. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405094 Fri, 26 Aug 2011 04:00:00 +0100 5405094 http://www.medworm.com/index.php?rid=5405093&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001673%2Fabstract%3Frss%3Dyes Conclusion: The main advantages of this method are its simplicity and low cost. Using this method does not require any special equipment and the problem of postoperative ischemic complications due to vascular injury, kinking and vasospasms can be addressed. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405093 Fri, 26 Aug 2011 04:00:00 +0100 5405093 http://www.medworm.com/index.php?rid=5405092&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001478%2Fabstract%3Frss%3Dyes Highlights: ► We studied comorbid cerebrovascular disease (CVD) in idiopathic Parkinson's disease (IPD) ► We found radiological and clinical CVD to be significantly increased in IPD ► Significantly more IPD patients with radiological CVD had postural instability ► The association between CVD and IPD merits further studyAbstract: Comorbid cerebrovascular disease (CVD) can occur in idiopathic Parkinson's disease (IPD) but its reported prevalence varies considerably. CVD may alter the clinical presentation, course and prognosis in IPD. We aimed to determine the prevalence of radiological and clinical CVD in a neurology clinic IPD population. We undertook a retrospective case–control study of neurology clinic patients with IPD for whom cerebral imaging was available, and excluding pr... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5405092 Fri, 26 Aug 2011 04:00:00 +0100 5405092 http://www.medworm.com/index.php?rid=5282591&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002307%2Fabstract%3Frss%3Dyes Conclusions: Widening of the IAC by tumor growth may leads to obliteration of air cells in the PW and therefore can be protective concerning CSF-fistula. At the same time patients with small tumors and a visible pneumatization in the PW must be expected to have a higher risk of CSF-fistula. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282591 Fri, 26 Aug 2011 04:00:00 +0100 5282591 http://www.medworm.com/index.php?rid=5282590&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002319%2Fabstract%3Frss%3Dyes Conclusion: We demonstrate dementia is a considerable health problem in an urban Belgian population of community-dwelling elderly aged between 75 and 80 years old. In order to prepare health care and social security systems for the future management of dementia, proper epidemiological insight into the current and future magnitude of the burden of dementia, taking into account socio-economic differences, to which this study contributes, are required. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282590 Fri, 26 Aug 2011 04:00:00 +0100 5282590 http://www.medworm.com/index.php?rid=5282586&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002137%2Fabstract%3Frss%3Dyes Conclusion: The LPG cellu M6 keymodule is a mechanotransduction machine that stimulates the skin's surface in triggering cells to activate lipolysis and collagen production. It has never been used for treatment of lipoatrophy due to drug treatment or in specific diseases associated with lipoatrophy (diabetes, HIV). The prevention and management of lipoatrophy includes patient education, regular examination and manual palpation of all injection sites. LPG endermology can help patients to resolve this side effect and to continue immunomodulatory treatment. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282586 Fri, 26 Aug 2011 04:00:00 +0100 5282586 http://www.medworm.com/index.php?rid=5282585&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711002113%2Fabstract%3Frss%3Dyes Conclusion: In this study, a large proportion of persons who sustained a MTBI experienced persistent symptoms up to one year after trauma. MTBI might have significant and lasting impact on the quality of life, which is to be verified by further studies. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282585 Fri, 26 Aug 2011 04:00:00 +0100 5282585 http://www.medworm.com/index.php?rid=5282584&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001879%2Fabstract%3Frss%3Dyes Conclusions: In patients with cerebral SVD there is a positive association of increased plasma tHcy levels with clinical status and severity of WMC. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5282584 Fri, 26 Aug 2011 04:00:00 +0100 5282584 http://www.medworm.com/index.php?rid=5174319&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001260%2Fabstract%3Frss%3Dyes I read with great interest the article by Bailey et al. entitled ‘Phase-contrast cine MRI revealing en valve mechanism in spontaneous third ventriculostomy: report of a case and literature review’ . In this case report, the authors analyzed the usage of phase-contrast cine magnetic resonance imaging (PC-MRI) in the patients with spontaneous third ventriculostomy (STV). (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174319 Thu, 25 Aug 2011 23:00:00 +0100 5174319 http://www.medworm.com/index.php?rid=5174318&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000850%2Fabstract%3Frss%3Dyes Primary, non traumatic intracerebral hemorrhage results from the rupture of small vessels mostly damaged by chronic hypertension or amyloid angiopathy . Commonly, it occurs in the basal ganglia, thalamus, brain stem, cerebellum and the cerebral lobes. Secondary intracerebral hemorrhage is induced by vascular abnormalities or impaired coagulation. Chronic hypertension is the most important risk factor for spontaneous intracerebral hemorrhage . Recent studies speculate that acute hypertension may contribute to intracerebral hemorrhage . A few patients were reported to have suffered hemorrhagic stroke in association with the use of over-the-counter sympathomimetics like phenylpropanolamine, pseudoephedrine and epinephrine . Rarely, intracerebral hemorrhage occurred after intravenous administr... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174318 Thu, 25 Aug 2011 23:00:00 +0100 5174318 http://www.medworm.com/index.php?rid=5174317&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001296%2Fabstract%3Frss%3Dyes Not more than 40 cases of Creutzfeldt–Jakob disease (CJD) in which the methionine-to-arginine point mutation in codon 232 (M232R) was detected in the prion protein gene (PRNP) have been reported; of these, all have occurred in Japan , except for one case in China and one in Korea . The initial clinical features are gait disturbance, disorientation, memory disturbance, visual impairment, and finger tremors, and these symptoms progress to myoclonus and akinetic mutism. As far as can be established from previous reports, most cases with the M232R point mutation in PRNP exhibit the 14-3-3 protein on cerebrospinal fluid (CSF) immunoassay, as well as methionine/methionine homozygosity at codon 129 in PRNP . In the present report, we present the case of a patient in whom PRNP included valine/me... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174317 Thu, 25 Aug 2011 23:00:00 +0100 5174317 http://www.medworm.com/index.php?rid=5174316&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001314%2Fabstract%3Frss%3Dyes We describe a patient with chemotherapy-responsive, anti-Yo-autoantibody-associated paraneoplastic RT and summarize clinical information on five previous patients, paraneoplastic RT. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174316 Thu, 25 Aug 2011 23:00:00 +0100 5174316 http://www.medworm.com/index.php?rid=5174315&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001259%2Fabstract%3Frss%3Dyes We report a case of a 36-year-old woman who developed a headache, persistent nausea, and vomiting because of subarachnoid hemorrhage (SAH) that occurred after EBP. We suggest that EBP can result in SAH even if inadvertent puncture is avoided. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174315 Thu, 25 Aug 2011 23:00:00 +0100 5174315 http://www.medworm.com/index.php?rid=5174314&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001272%2Fabstract%3Frss%3Dyes Primary cerebral vasculitis is a rare disease. There are considerable difficulties in recognition and diagnosis in the absence of systemic involvement. Primary angiitis of the central nervous system causes focal and diffuse neurologic symptoms . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174314 Thu, 25 Aug 2011 23:00:00 +0100 5174314 http://www.medworm.com/index.php?rid=5174313&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001284%2Fabstract%3Frss%3Dyes Hypokalaemic periodic paralysis (HOKPP, OMIM 170400) is a rare dominantly inherited disorder, which in approximately 70% of cases results from mutation in the CACNA1S calcium channel gene. It presents clinically with attacks of flaccid limb muscle weakness . Multiple sclerosis (MS) is a more common inflammatory disease of the central nervous system characterized by episodic or progressive neurological disability. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174313 Thu, 25 Aug 2011 23:00:00 +0100 5174313 http://www.medworm.com/index.php?rid=5174312&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001119%2Fabstract%3Frss%3Dyes We report the first case of VIOM using cortical VEPs in a patient undergoing occipital arteriovenous malformation (OAVM) resection. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174312 Thu, 25 Aug 2011 23:00:00 +0100 5174312 http://www.medworm.com/index.php?rid=5174311&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001120%2Fabstract%3Frss%3Dyes Hashimoto encephalopathy (HE) is a rare disorder with an estimated prevalence of about 2.1/100000. HE is diagnosed in patients with otherwise unexplained neurological and/or psychiatric symptoms in whom antithyroid antibodies are positive regardless of their thyroid function. The core presenting feature of HE is a progressive or fluctuating encephalopathy with alterations of mental state and changes in behavior and personality. Other common features are seizures, myoclonus, tremor and stroke-like episodes. Mean age of onset is between 45 and 55 years of age, with a female predominance of 5:1. Only about 27 pediatric patients with HE are reported. Children present more with seizures, confusion, headache, hallucinations and ataxia. In contrast to adults, gender distribution is equal in child... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174311 Thu, 25 Aug 2011 23:00:00 +0100 5174311 http://www.medworm.com/index.php?rid=5174310&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001107%2Fabstract%3Frss%3Dyes Conclusion: This is the first report of a sellar/parasellar paraganglioma extending into the orbit through the superior orbital fissure. While an appropriate treatment paradigm has not been established, a review of all previously reported cases suggests that radiotherapy is an important consideration. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174310 Thu, 25 Aug 2011 23:00:00 +0100 5174310 http://www.medworm.com/index.php?rid=5174309&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001065%2Fabstract%3Frss%3Dyes We present a case of myasthenia gravis developed 3 years after known HIV infection and discuss the impacts of antiretroviral therapy. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174309 Thu, 25 Aug 2011 23:00:00 +0100 5174309 http://www.medworm.com/index.php?rid=5174308&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000813%2Fabstract%3Frss%3Dyes Stereotactic radiosurgery has become an effective and safe treatment for cerebral arteriovenous malformations (AVMs) during the last two decades. More than 900 patients with AVMs have undergone GKS in Taipei Veteran General Hospital until now. In our series published in 2000, Pan et al. reported 240 AVM patients treated by GKS , and overall 75% complete obliteration rate would be achieved after 40 months follow-up. Furthermore, the complete obliteration rates of small, medium, and large AVMs at 40-month follow up were 92%, 80%, and 50%, respectively. In 2009, the authors reported 105 pediatric and 458 adult AVM patients treated by GKS , and the complete obliteration rate at 48 months follow-up was 65% in adult group, compared to 47% in pediatric group. The pediatric AVMs seemed to respond ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174308 Thu, 25 Aug 2011 23:00:00 +0100 5174308 http://www.medworm.com/index.php?rid=5174307&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000837%2Fabstract%3Frss%3Dyes We present a case of a 35 year-old male with Blastomyces dermatitidis meningitis as the primary presentation of blastomycosis infection, without evidence of involvement outside the CNS at time of discharge. We focus on the magnetic resonance imaging findings, with histopathologic correlation. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174307 Thu, 25 Aug 2011 23:00:00 +0100 5174307 http://www.medworm.com/index.php?rid=5174306&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000709%2Fabstract%3Frss%3Dyes Abstract: Of the 15 cases of intradural extramedullary ependymomas in the literature, only 3 patients were male. The authors report the fourth case to be diagnosed in a male patient and discuss the pathogenesis, presentation, and treatment of this rare form of ependymoma. These cases most commonly show a similar clinical preoperative course to that of a benign meningioma. Although most instances have been reported in females, hormonal influence may not completely explain this neoplasm's pathogenesis. Close follow-up is warranted because of potential recurrence, metastasis, and anaplastic transformation. An ependymoma should be included in the differential diagnosis of intradural extramedullary tumors. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174306 Thu, 25 Aug 2011 23:00:00 +0100 5174306 http://www.medworm.com/index.php?rid=5174305&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001466%2Fabstract%3Frss%3Dyes Conclusion: A spinal cord syndrome was the most common initial presentation of our Chinese CIS group. After a mean follow-up of 38 months, the conversion rate to MS was approximately 25%. The 2005 revised McDonald MRI criteria for dissemination in space is a key prognostic factor for conversion to MS in CIS in Chinese patients. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174305 Thu, 25 Aug 2011 23:00:00 +0100 5174305 http://www.medworm.com/index.php?rid=5174304&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001442%2Fabstract%3Frss%3Dyes Conclusions: With respect to the patients aged (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174304 Thu, 25 Aug 2011 23:00:00 +0100 5174304 http://www.medworm.com/index.php?rid=5174303&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001399%2Fabstract%3Frss%3Dyes Abstract: Depression is found to be present in up to 44% of brain tumor patients during their illness process. Anxiety as a comorbid psychiatric disorder with depression has formerly been studied, but phobia or obsessive–compulsive symptoms among brain tumor patients have not yet been noticed.By using a clinical prospective database of primary brain tumor patients (n=77) we studied the level of depression, anxiety, obsessionality (traits and symptoms) and phobic anxiety symptoms. Psychiatric symptoms were assessed before tumor operation as well as at three months and at one year after operation. The presence of comorbid anxiety, obsessionality and phobic anxiety symptoms was assessed before operation and at follow-ups in depressed and non-depressed patients, separately.Before tumor opera... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174303 Thu, 25 Aug 2011 23:00:00 +0100 5174303 http://www.medworm.com/index.php?rid=5174301&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001417%2Fabstract%3Frss%3Dyes Conclusion: Burden of care is significantly more in PD patients of advanced age and stage of illness. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174301 Thu, 25 Aug 2011 23:00:00 +0100 5174301 http://www.medworm.com/index.php?rid=5174300&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001454%2Fabstract%3Frss%3Dyes Conclusion: Fundoscopy is an extremely useful non-invasive tool to assess changes in intracranial pressure in severe head injury. Reappearance of papilloedema in the postoperative period even in the absence of ventriculomegaly indicates raised ICP and should be treated aggressively. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174300 Thu, 25 Aug 2011 23:00:00 +0100 5174300 http://www.medworm.com/index.php?rid=5174299&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100134X%2Fabstract%3Frss%3Dyes This study was a case series including all referred patients with definite diagnosis of cubital tunnel syndrome, treated by anterior subcutaneous transposition. Treatment results were measured according to modified Bishop rating system, and were ranked into excellent, good, fair, and poor. Variables such as gender, age (less/more than 45 years), causation, and initial severity, determined by Dellon criteria preoperatively, were analyzed by Fisher's exact test.Results: This study was performed on 26 eligible cases including 29 elbows, 38% males and 62.1% females, with mean age of 44.5 years (ranging 23–72 years). In a 12 months follow-up post-operatively, 62% showed excellent, 20.7% good, and 17.3% fair, with no poor result. In a 1–12 months follow-up post-operatively, results showed im... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174299 Thu, 25 Aug 2011 23:00:00 +0100 5174299 http://www.medworm.com/index.php?rid=5174298&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001302%2Fabstract%3Frss%3Dyes Conclusion: The endonasal transsphenoidal technique is a safe, quick, and effective approach to pituitary adenomas. Our guidance frame allows the surgeon to open and close the wound rapidly, which avoids trajectory deviation and shortens the duration of the surgical procedure. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174298 Thu, 25 Aug 2011 23:00:00 +0100 5174298 http://www.medworm.com/index.php?rid=5174297&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001326%2Fabstract%3Frss%3Dyes Conclusion: The presence of moderate to severe depression significantly correlated with socioeconomic status, use of emergency room, and presence of headache/pain. Neurology clinics with predominantly underserved immigrant patients have a disproportionate amount of depression, which may be related to socioeconomic factors resulting in overutilization of scarce healthcare resources. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174297 Thu, 25 Aug 2011 23:00:00 +0100 5174297 http://www.medworm.com/index.php?rid=5174295&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001090%2Fabstract%3Frss%3Dyes Conclusions: This was the first MRA-based study to take into consideration the clinical, cognitive and functional outcomes in ischemic stroke patients with SLAD. Patients with SLAD had poorer cognitive and functional outcomes when compared to patients without SLAD. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174295 Thu, 25 Aug 2011 23:00:00 +0100 5174295 http://www.medworm.com/index.php?rid=5174294&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001053%2Fabstract%3Frss%3Dyes Conclusions: The present report describes the successful use of a monoshaft bipolar cautery and its application in a bimanual hemostatic device system. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5174294 Thu, 25 Aug 2011 23:00:00 +0100 5174294 http://www.medworm.com/index.php?rid=5049244&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000746%2Fabstract%3Frss%3Dyes It was with great sadness that I read the report of yet another fatal error involving the administration of vincristine via the intrathecal route . The article's focus is the management of vincristine-induced neurotoxicity, providing little insight into how the error occurred. Many questions need to be answered before we can understand the reasons behind this tragic mistake. However, the most import question is; how was the vincristine prepared for administration? Was it prepared in a syringe? (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049244 Fri, 22 Jul 2011 01:50:10 +0100 5049244 http://www.medworm.com/index.php?rid=5049243&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000734%2Fabstract%3Frss%3Dyes In the case report, by Reddy et al. , the authors ask a pertinent question, how can a patient be saved from inadvertent intrathecal vincristine? While the actions taken by the treating clinicians can be seen as a heroic failure, the pharmacokinetic characteristics of the medication itself essentially determined the outcome of this patient. Vincristine has been shown to bind to tubulin in less than 5min , so the discovery of the event 40min after it occurred was relatively rapid; likely resulted in a situation in which any intervention to change the outcome would have been futile. As the authors note, there have been only 6 cases in the literature where a patient has not died as a consequence of this medication error. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049243 Fri, 22 Jul 2011 01:50:10 +0100 5049243 http://www.medworm.com/index.php?rid=5049242&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000722%2Fabstract%3Frss%3Dyes We report a 41-year-old man that presented with cervical choreatiform dyskinesia. Neurological examination was normal except vertical gaze palsy and cognitive fluctuations in memory and visuoconstruction. He reported that he had a history of perinatal brain bleeding but a consecutive normal development. He was working as an administration employee. A few months before onset of the dyskinesia, he had developed headache and nausea. Cranial MRI showed a large right residual porencephalic cyst communicating with the ventricular systems and compromising the right hemisphere. Furthermore the MRI showed a hydrocephalus internus of the lateral ventricle of the left hemisphere and the third ventricle. A membranous formation in the cerebral aqueduct with surrounding blood was the suspected cause for... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049242 Fri, 22 Jul 2011 01:50:09 +0100 5049242 http://www.medworm.com/index.php?rid=5049241&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000692%2Fabstract%3Frss%3Dyes It has been proposed that VNS could be a worthy and effective alternative remedial technique in patients with cerebral palsy and seizures especially refractory seizures . The proposal is fundamentally based on the dual influence of VNS i.e. seizure-suppression and interictal discharges (IEDs)-reduction with the purpose of seeking improved prognostic outcome and quality of life (QOL). Continued research on VNS mechanisms has yielded fresh evidence that strengthens the above proposal of VNS implantation in such patients. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049241 Fri, 22 Jul 2011 01:50:08 +0100 5049241 http://www.medworm.com/index.php?rid=5049240&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000710%2Fabstract%3Frss%3Dyes The new Neuromethods series, now published by Springer Science+Business Media (previously Humana Press), focuses on methodologies or approaches either unique to the investigation of the nervous system or that require special consideration to be applied to the neurosciences. One of the more recent additions to this series is Animal Models of Pain, edited by Chao Ma and Jun-Ming Zhang. Chao Ma is assistant professor in the Department of Anesthesiology at Yale University School of Medicine, New Haven, CT. He studies the aetiology and treatment of chronic pain by focusing on antigen-specific immune mechanisms of chronic pain and the mechanisms of hyperexcitability in primary sensory neurons after injury or inflammation in the peripheral nervous system. Jun-Ming Zhang is associate professor in ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049240 Fri, 22 Jul 2011 01:50:07 +0100 5049240 http://www.medworm.com/index.php?rid=5049239&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000801%2Fabstract%3Frss%3Dyes We describe a case in which we utilized CT perfusion (CTP) to acutely measure cerebral blood flow (CBF) in an ICH patient following a precipitous fall in BP. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049239 Fri, 22 Jul 2011 01:50:07 +0100 5049239 http://www.medworm.com/index.php?rid=5049238&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000758%2Fabstract%3Frss%3Dyes We present a patient with CIDP associated with ITP and cutaneous T-cell lymphoma. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049238 Fri, 22 Jul 2011 01:50:06 +0100 5049238 http://www.medworm.com/index.php?rid=5049237&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000643%2Fabstract%3Frss%3Dyes Intracranial meningiomas are tumors arising from the arachnoidal cells. They are considered as being rarely invasive. The incidence averages 2.6 per 100,000 population. There is a broad diversity of histopathological variants of meningiomas , and the gold standard for curative treatment is radical surgical removal according to Simpson . Atypical meningiomas are more aggressive, tend to recur earlier and invade the surrounding structures of the skull and the brain . Despite their higher malignancy, extracranial metastases of atypical meningiomas are extremely rare with an estimated incidence of 1–5 out of 1000 cases . (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049237 Fri, 22 Jul 2011 01:50:06 +0100 5049237 http://www.medworm.com/index.php?rid=5049236&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000527%2Fabstract%3Frss%3Dyes We describe two cases having weakness in the limbs with involvement of bulbar nerve-innervated muscles and respiratory muscles. They were initially diagnosed as having Guillain–Barré syndrome (GBS). Subsequent clinical and imaging features supported the diagnosis of bilateral MMI. The clinical features and differential diagnosis of bilateral MMI will be discussed in this report. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049236 Fri, 22 Jul 2011 01:50:05 +0100 5049236 http://www.medworm.com/index.php?rid=5049235&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000485%2Fabstract%3Frss%3Dyes We report a case of a young woman presenting with recurrent ischemic strokes who was finally diagnosed with Fabry disease after impaired kidney function had been identified. Fabry disease should be considered in unexplained cases of first or recurrent strokes in young patients disregarding the gender of the patient, especially when chronic kidney disease and/or proteinuria are present. Renal function should be closely monitored in patients with strokes and followed up after the event. In this case, intravenous thrombolysis was performed after the second ischemic event. No other case of thrombolysis for ischemic stroke in Fabry disease has been described in the literature. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049235 Fri, 22 Jul 2011 01:50:05 +0100 5049235 http://www.medworm.com/index.php?rid=5049234&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000461%2Fabstract%3Frss%3Dyes Abstract: Cystic choroid plexus papilloma (CPP) of the third ventricle is rare. The authors have reported a case of cystic CPP resected successfully through neuroendoscopic approach. An 18-year-old young man was admitted to our hospital, presented with blurred vision and paroxysmal, intermittent, severe headache for 1 month as well as nausea and vomiting. The findings of neurological examination were normal except for a bilateral papilledema. Magnetic resonance and computerized tomography revealed a cystic lesion in the third ventricle, which did not furnish a definite diagnosis. The tumor was totally resected through neuroendoscopic approach and was found in histopathological examination to be a CPP. The patient retained free of symptoms at 2 year follow-up. To the best of the authors’ ... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049234 Fri, 22 Jul 2011 01:50:05 +0100 5049234 http://www.medworm.com/index.php?rid=5049233&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS030384671100045X%2Fabstract%3Frss%3Dyes Abstract: Penetration of the optic apparatus by an anterior communicating artery (ACoA) aneurysm is unique. A 43-year-old woman with a history of visual disturbance due to a previous aneurismal rupture underwent surgical neck clipping for a recurred ACoA aneurysm, which had previously been treated using detachable coils. The operation confirmed that the recurred aneurysm and the packed coils had penetrated the chiasm and the right optic nerve (ON), which was distorted and thinned. The aneurismal neck was clipped and the coils were left in place because damage to the optic apparatus by penetration is usually irreversible. As the patient was semicomatous at the former admission due to subarachnoid hemorrhage (SAH), she became aware of the visual disturbance 2 weeks after ictus when she had i... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049233 Fri, 22 Jul 2011 01:50:03 +0100 5049233 http://www.medworm.com/index.php?rid=5049232&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000424%2Fabstract%3Frss%3Dyes This study reports a case of thoracic spinal epidural hematoma following spinal manipulative therapy in the absence of predisposing factors. The effectiveness and safety of chiropractic treatment in chronic spinal pain and a literature review are also presented. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049232 Fri, 22 Jul 2011 01:50:03 +0100 5049232 http://www.medworm.com/index.php?rid=5049231&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001351%2Fabstract%3Frss%3Dyes Conclusion: Symptoms related to mastocytosis may be encountered by neurologists and mimic many common, often idiopathic syndromes including, syncopal spells, back pain, and headache. In our cohort, multiple sclerosis may be over-represented. Mastocytosis should be considered in patients with these presentations, especially when also accompanied by flushing, abdominal cramping or diarrhea. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049231 Fri, 22 Jul 2011 01:50:02 +0100 5049231 http://www.medworm.com/index.php?rid=5049230&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711001041%2Fabstract%3Frss%3Dyes Conclusion: The use of neuroimaging and functional navigation technologies may effectively lower the incidence of postoperative complications. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049230 Fri, 22 Jul 2011 01:50:02 +0100 5049230 http://www.medworm.com/index.php?rid=5049229&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000874%2Fabstract%3Frss%3Dyes Abstract: Sporadic inclusion body myositis (sIBM) usually occurs as an isolated condition, but it may occur in association with another autoimmune disorder such as Sjögren's syndrome. We reviewed sIBM cases with Sjögren's syndrome (sIBM/SS) from the Perth Inflammatory Myopathies Database to determine whether they are distinguishable from other sIBM cases. Six such cases were identified, representing 12% of all sIBM cases. Muscle biopsies confirmed the presence of an inflammatory myopathy with rimmed vacuoles and the characteristic muscle fibre inclusions of sIBM. Five of the six were females, contrasting with a 2:1 male preponderance in the rest of the sIBM cohort. The mean age-at-onset and the pattern of muscle weakness were similar in the two groups. Four out of five sIBM/SS patients t... Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049229 Fri, 22 Jul 2011 01:50:02 +0100 5049229 http://www.medworm.com/index.php?rid=5049228&cid=s_35403_153_f&fid=35403&url=http%3A%2F%2Fwww.clineu-journal.com%2Farticle%2FPIIS0303846711000862%2Fabstract%3Frss%3Dyes Conclusions: Our findings point to a positive effect of short duration rTMS in tinnitus treatment using the THI. However, no significant benefits were demonstrated for other subjective patient ratings. Although well tolerated and convenient, short duration rTMS may prove inadequate for modulating maladaptive plastic changes at the cortical level, and our results suggest the need for delivery of more stimuli. Future studies will utilize at least 2000 pulses/day, in line with previous experience in Western settings. (Source: Clinical Neurology and Neurosurgery) Clinical Neurology and Neurosurgery journals http://www.medworm.com/rss/comments.php?id=5049228 Fri, 22 Jul 2011 01:50:00 +0100 5049228