MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Clinical Neurophysiology' source. Mon, 15 Mar 2010 17:01:56 +0100 http://www.medworm.com/index.php?rid=3342493&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007937%2Fabstract%3Frss%3Dyes Introduction: In the development of children’s cognitive abilities making doll models plays an important role. Aim: Aim of this work was to develop children’s cognitive ability through visual art. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342493 Mon, 08 Mar 2010 18:13:11 +0100 3342493 http://www.medworm.com/index.php?rid=3342492&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007391%2Fabstract%3Frss%3Dyes Autism is severe developmental disorder with onset around age of three years. Main characteristics of autistic children are problems with social interaction, emotional correspondence and difficulty with verbal and nonverbal communication. One of the most intriguing questions is the possible reasons causing the expression of autism. Aim of this study was to evaluate the possible prenatal causes for clinical expression of autism. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342492 Mon, 08 Mar 2010 18:13:11 +0100 3342492 http://www.medworm.com/index.php?rid=3342491&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS138824570900738X%2Fabstract%3Frss%3Dyes The aim was to identify the frequency and level of anxiety in the patients with rheumatoid arthritis (RA). In 60 patients with RA, aged 49.87±7.56 yrs., we evaluated: disease activity by DAS28 score, functional ability by the HAQ, and anxiety by Spielberger test (state and trai anxiety). (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342491 Mon, 08 Mar 2010 18:13:11 +0100 3342491 http://www.medworm.com/index.php?rid=3342490&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007378%2Fabstract%3Frss%3Dyes The aim was to examine the impact of the pain on the cognitive abilities in the patients with rheumatoid arthritis (RA). Material and methods: we investigated 60 patients with RA and 30 healthy subjects. The intensity of pain was determined by VAS, cognitive abilities by the Wechsler memory scale, functional ability by HAQ questionnaire, and disease activity by DAS28 score. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342490 Mon, 08 Mar 2010 18:13:11 +0100 3342490 http://www.medworm.com/index.php?rid=3342489&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007366%2Fabstract%3Frss%3Dyes The object of this investigation are mental processes of expectation, attention, and learning, related to the level of physical activity. The experimental part of this work is carried out on 50 subjects, divided by amount of physical activity into 2 groups: sedentary and recreational. All subjects were included in electrophysiological testing with electroexpectogram (EXG) paradigm. EXG paradigm is dynamic extension of classical contingent negative variation (CNV) paradigm. The S1–S2 pair is applied until the CNV rises up to a certain threshold. After that, S2 is turned off, until the CNV falls below the threshold level. Sedentary group, consists of 25 subjects, mean age 20.57 years, mean duration of education 12.32±1.21 shows next EXG parameters: number of formed EXG cycles 2.27 ±1.42;... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342489 Mon, 08 Mar 2010 18:13:11 +0100 3342489 http://www.medworm.com/index.php?rid=3342488&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007354%2Fabstract%3Frss%3Dyes Background: Guillain–Barre‘ syndrome (GBS) and Miller–Fisher syndrome are variant forms of acute demyelinating polyradiculoneuropathy. Lack of multiple relapses have differentiated it from the chronic form. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342488 Mon, 08 Mar 2010 18:13:11 +0100 3342488 http://www.medworm.com/index.php?rid=3342487&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007342%2Fabstract%3Frss%3Dyes Purpose: Estimation of changes and value of somatosensory evoked potentials (SEPs) in patients with cervical disc herniation. Methods: We included 48 patients with NMR confirmed cervical disc herniation. Cervical spine cord compression was found in 21 pat., and a narrowing of spinal channel in the rest. SEPs were elicited by stimulation of tibial nerves and wave P40 parameters and central conduction time were analyzed. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342487 Mon, 08 Mar 2010 18:13:11 +0100 3342487 http://www.medworm.com/index.php?rid=3342486&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007330%2Fabstract%3Frss%3Dyes Introduction: Thoracic Outlet Syndrome (TOS) compromised circulation in the cervical region. The aim of the study was to evaluate the quality of sleeping in these patients. Methods: 90 patients (20 males and 70 females) aged 52.4 (28–76) filled a sleep questionnaire. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342486 Mon, 08 Mar 2010 18:13:11 +0100 3342486 http://www.medworm.com/index.php?rid=3342485&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007329%2Fabstract%3Frss%3Dyes We present a l6-year-old young man with four different types of RMDs. At the age of 2.5 years symptoms spontaneously appeared as repetitive, rhythmic, stereotypic, sleep-related rhythmic movements of forward and backward swaying of the trunk (body rocking). After four years of age the movements transformed to head banging against a pillow appearing in quiet wakefulness or superficial sleep. From the age of 7 years he had body rolling and head rolling as pre-sleep behavior. Head banging, body or leg rolling appeared in random succession, in different combinations or independently as isolated symptom on a particular night. Patient never hurt himself, claimed to be amnesic for the events with daily activities unaffected. PSG with sleep architecture, neurologic, psychiatric, cardiologic, ophth... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342485 Mon, 08 Mar 2010 18:13:09 +0100 3342485 http://www.medworm.com/index.php?rid=3342484&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007317%2Fabstract%3Frss%3Dyes Purpose: An ambulatory system that applies functional electrical stimulation (FES) for tremor attenuation relies on the information when the movement will start. Brain computer interface (BCI) is at disposal to drive the system. We propose the computing method for the evaluation of various arm movements in order to detect intention to move prior to the movement. Method relies on the fact that Bereitschaftspotential (BP) is a measure of activity in the brain that is related to the planning of movement. The database was created for the Tremor project (FP7) and contains signals from standard EEG recordings. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342484 Mon, 08 Mar 2010 18:13:09 +0100 3342484 http://www.medworm.com/index.php?rid=3342483&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007305%2Fabstract%3Frss%3Dyes We present 19 year-old boy who has been suffering from paroxysmal nocturnal attacks of painful dystonic postures involving one hand, neck and eyes, for several years. The consciousness is always preserved, standard day-time EEG examinations are normal. Initial therapeutical response to carbamazepine was effective. During the clinical course, and disease aggravation, ictal sleep EEG suggested epileptic frontal lobe discharges. Although PND and ADNFLE are very similar diseases, their electrophysiological differences suggest the most important role of EEG in establishing the final, correct diagnosis of some neurological diseases. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342483 Mon, 08 Mar 2010 18:13:09 +0100 3342483 http://www.medworm.com/index.php?rid=3342482&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007299%2Fabstract%3Frss%3Dyes We present a simple method in the time domain for evaluating episodes of freezing of gait (FOG) in Parkinson’s disease (PD) patients by using ground reaction forces. Methods: Three sources were applied to study gait: video, force sensitive resistors (FSR) attached to one foot, and accelerometers in pairs attached to the foot, shank and thigh. Task included walking through the corridor, doorway pass, U-turn and approaching the destination. We analyzed 24 FOG episodes from 9 PD patients in “on” state. In addition to common methods for time analysis based on video, ground reaction forces and accelerations, we computed Pearson’s correlation coefficient (Pcc) between a “regular/normal” step and the complete record from FSR. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342482 Mon, 08 Mar 2010 18:13:09 +0100 3342482 http://www.medworm.com/index.php?rid=3342481&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007287%2Fabstract%3Frss%3Dyes Purpose: Quantitative analysis of anxiety level in patient groups with generalized and focal, temporal or extratemporal epilepsy. Material and method: Ninety patients (30 with generalized epilepsy, 30 with temporal and 30 with extratemporal epilepsy), and age-matched healthy control subjects were investigated. Anxiety level in all subjects was assessed with Beck Anxiety Inventory. Sheehan Disability Scale was used to determine the functional disability level. Patients with comorbid major depression, schizophrenia or bipolar disorder, progressive neurological disease, alcoholism, and epilepsy associated with mental retardation were excluded. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342481 Mon, 08 Mar 2010 18:13:09 +0100 3342481 http://www.medworm.com/index.php?rid=3342480&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007275%2Fabstract%3Frss%3Dyes Purpose: Topiramate (TPM) is a new antiepileptic drug (AED) with proven efficacy and safety. We investigated long-term efficacy and tolerability of TPM as add-on therapy in patients with refractory epilepsy. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342480 Mon, 08 Mar 2010 18:13:09 +0100 3342480 http://www.medworm.com/index.php?rid=3342479&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007263%2Fabstract%3Frss%3Dyes Purpose: To present the clinical course and the crucial diagnostic video EEG record of a female infant subsequently diagnosed to have infantile masturbation. Method: Patient medical records and video-EEG analysis. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342479 Mon, 08 Mar 2010 18:13:09 +0100 3342479 http://www.medworm.com/index.php?rid=3342478&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007251%2Fabstract%3Frss%3Dyes Purpose: To present non-convulsive status epilepticus in elderly patients who also manifested acute confusional state, which was properly diagnosed only after a few days of different diagnostic explorations. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342478 Mon, 08 Mar 2010 18:13:09 +0100 3342478 http://www.medworm.com/index.php?rid=3342477&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS138824570900724X%2Fabstract%3Frss%3Dyes Purpose: To determine the frequency, type and location of interictal EEG abnormalities in patients with pharmacoresistant epilepsy (PRE). Method: From 80 randomly chosen patients with partial epilepsy, age 18–60 years, follow-up period at least 4 years, we formed two groups of 40 patients, one with PRE and one with controlled seizures (CE). (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342477 Mon, 08 Mar 2010 18:13:09 +0100 3342477 http://www.medworm.com/index.php?rid=3342476&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007238%2Fabstract%3Frss%3Dyes We present the results of testing of 48 patients (age 45–73) immediately after acute ischemic brain attack. A control group of healthy subjects of the same age was tested as well. The neurological examination as well as the brain computerized tomography was performed in all patients. According to these examinations, three groups of patients were formatted: ischemic attack in the anterior cerebral fossa, ischemic attack in the posterior fossa and diffuse lacunar ischemic changes of the brain. The testing was performed by means of the modified Brandt and coworkers SVV test. Static and dynamic SVV test was applied. The statistical analysis by means of Student’s test and Mann–Whitney test, showed much bigger inaccuracy in judging of verticality in the group of patients, compared to the g... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342476 Mon, 08 Mar 2010 18:13:08 +0100 3342476 http://www.medworm.com/index.php?rid=3342475&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007226%2Fabstract%3Frss%3Dyes The goal of this study was to investigate the usefulness of the vestibular stimulation in rehabilitation of patients after Spinal Cord Injury (SCI). The activation of vestibulospinal pathways can be achieved by galvanic stimulation applied to the mastoid. It causes hypotonia of the extensor muscles on the anodal side. In 9 chronic SCI patients (aged 21–41), a repeated galvanic stimulation was applied on the left, and after that, on the right mastoid. Two of the patients were grade A according to American Spinal Injury Association (ASIA) Impairment Scale (AIS), 5 grade B, and two grade C. The intensity of the stimulation was 3–5mA, the duration 1s. Each stimulus was repeated 10 times. The spasticity of lower limbs was tested previous and after galvanic stimulation. Two experienced physi... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342475 Mon, 08 Mar 2010 18:13:08 +0100 3342475 http://www.medworm.com/index.php?rid=3342474&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007214%2Fabstract%3Frss%3Dyes Neonatal hearing screening is a well established diagnostic method. In contrast, function of the vestibular apparatus and its central pathways is hardly being examined in newborns The aim of this research was to examine functioning of the vestibular apparatus and its pathways in newborns. In N=100 healthy full-term newborns from regular pregnancies, we performed the following clinical examinations: observation of ocular alignment in the awake state (OAA), testing of the vestibulo-ocular reflex (VOR) and testing of the Moro reflex (MOR). The results were scored, and recorded by means of a digital camera. In 87% of babies eyes were in the midline, whereas in 13% of babies one or both eyes were in exotropia or endotropia. VOR was absent in 5% of newborns, present to both sides in 38%. In rema... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342474 Mon, 08 Mar 2010 18:13:04 +0100 3342474 http://www.medworm.com/index.php?rid=3342473&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007202%2Fabstract%3Frss%3Dyes Otoacoustic emissions are acoustic signals generated by cochlea’s outer hair cells. They can be detected in the ear canal of a person with normal outer hair cell function. During the last decade, the detection of otoacoustic emissions has become a well established method of neonatal hearing screening. Besides that, they have become a inevitable tool in the hearing-impairment diagnostic procedure. In this presentation, the Transient Evoked Otoacoustic Emission (TEOAE) measurement is described. Three cases of hearing impairment are demonstrated in which the TEOAE measurement had a significant contribution to the diagnosis. A case with tinnitus and normal pure tone audiometry, a case with vestibular neurinoma suspicion, and a case with industrial noise hearing impairment are described. (Sou... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342473 Mon, 08 Mar 2010 18:13:04 +0100 3342473 http://www.medworm.com/index.php?rid=3342472&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007196%2Fabstract%3Frss%3Dyes Purpose: To assess neurophysiologic improvement in audiological performance and short-term auditory memory of profoundly deaf children following cochlear implantation. Material and methods: Experimental group consisted of 30 profoundly deaf children with cochlear implants, aged 3–12 years. Control group had 30 profoundly deaf children with hearing aids of the same age. Ling 6 Sounds Test and Test of immediate verbal memory were used. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342472 Mon, 08 Mar 2010 18:13:04 +0100 3342472 http://www.medworm.com/index.php?rid=3342471&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007184%2Fabstract%3Frss%3Dyes Objective of our study was to define the causes of BD of patients who were candidates for organ donation and to define the reasons why some of them did not become brain-death donors. This retrospective study included patients that were treated at the Emergency department of the Clinical center of Serbia in the period from january 2004 until october 2008. The clinical diagnosis of brain death was confirmed in 133 patients. Considering the aetiology of BD the majority of cases (69.9%) included spontaneous hemorrhages (subarahnoidal and/or intracranial ones), and head injuries (10.5%). The organ transplantation was performed only in 24 cases (18.0%). In 69.9% cases the transplantation was not performed because of the refusal by the family (in 2004, 80%; in 2005, 80%; in 2006, 73.1%; in 2007, ... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342471 Mon, 08 Mar 2010 18:13:04 +0100 3342471 http://www.medworm.com/index.php?rid=3342470&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007172%2Fabstract%3Frss%3Dyes We present 20 neonates identified with a severe hypoxic–ischemic encephalopathy (HIE), in a 10-year period (1999–2009), subjected to electroencephalography. They all had isoelectric EEG during first 24–48h of life. Thirteen of 20 neonates also had electroencephalographic or other evidence of clinical seizures in first 72h of life. Serial EEGs (every 24h) helped assess the severity of a neonatal encephalopathy, but also may correlate with chronic and acute neurologic insults. Although electroencephalographic activity reemerged in 16 of these infants, significant clinical improvement was seen in only 5 patients. Four children died in first 72h of life, had continuous isoelectric EEG. Eleven children survived with severe sequaelae, had isoelectric EEG during period of et least 72h of li... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342470 Mon, 08 Mar 2010 18:13:04 +0100 3342470 http://www.medworm.com/index.php?rid=3342469&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007160%2Fabstract%3Frss%3Dyes The electroencephalography is by far the most used confirmatory test in the brain-dead (BD) diagnosis. Isoelectric electroencephalogram in conformance with clinical findings is strongly suggestive of brain death. In clinical practice, isoelectric electroencephalogram (EEG) in not-brain-dead patients is rarely seen. In period from 1999 to 2009, 36 patients (aged 1–18 years) with Glasgow comma score (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342469 Mon, 08 Mar 2010 18:13:04 +0100 3342469 http://www.medworm.com/index.php?rid=3342468&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007159%2Fabstract%3Frss%3Dyes The cerebral circulatory arrest (CCA) is the final step that leads to the irreversible loss of all brain functions and ultimately to the brain death. In contrast to the cerebral angiography, Transcranial Doppler sonography (TCD) is a noninvasive method that can detect CCA and can be easily performed at the bedside. In patients who have received sedatives, those with metabolic derangements or who are hypothermic TCD is more reliable than electroencephalography. Waveform abnormalities documented by the TCD occur when intracranial pressure increases above the mean arterial pressure and are indicative of CCA. The TCD criteria for CCA include the presence one of the following patterns: (1) biphasic oscillating flow (“to and fro” movement), (2) systolic spikes of low velocity without a flow ... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342468 Mon, 08 Mar 2010 18:13:04 +0100 3342468 http://www.medworm.com/index.php?rid=3342467&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007147%2Fabstract%3Frss%3Dyes Brain death (BD) is defined as irreversible loss of critical functions in the entire brain, including the brainstem. It is claimed that without the brain functions, the body functions will disintegrate. BD exams must show complete absence of brain function and must include two isoelectric (flat-line) EEGs, 24h apart. Although in certain countries EEG is not considered BD confirmatory test, since it cannot test brainstem function, majority of neurologists would not diagnose BD until the EEG is isoelectric. Therefore, EEG is necessary for confirmation of brain death in most countries, including Serbia. The major problem in BD concept is in the fact that brain functions may continue in many brain-dead brains. In our study out of 133 BD patients, 20 had persistent 24h brain function in EEG, th... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342467 Mon, 08 Mar 2010 18:13:04 +0100 3342467 http://www.medworm.com/index.php?rid=3342466&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007135%2Fabstract%3Frss%3Dyes Brain death (BD) is defined as the absence of all brain functions with the complete cessation of brain function, profound coma of known cause, complete absence of brain stem reflexes, and positive apnea test. All evaluations are done by experienced neurologist or neurosurgeons. Before a patient can be certified brain dead, a certain set of preconditions must be met: (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342466 Mon, 08 Mar 2010 18:13:04 +0100 3342466 http://www.medworm.com/index.php?rid=3342465&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007123%2Fabstract%3Frss%3Dyes We present a l6-year-old young man with four different types of RMDs. At the age of 2.5 years symptoms spontaneously appeared as repetitive, rhythmic, stereotypic, sleep-related rhythmic movements of forward and backward swaying of the trunk (body rocking). After four years of age the movements transformed to head banging against a pillow appearing in quiet wakefulness or superficial sleep. From the age of 7 years he had body rolling and head rolling as pre-sleep behavior. Head banging, body or leg rolling appeared in random succession, in different combinations or independently as isolated symptom on a particular night. Patient never hurt himself, claimed to be amnesic for the events with daily activities unaffected. PSG with sleep architecture, neurologic, psychiatric, cardiologic, ophth... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342465 Mon, 08 Mar 2010 18:13:03 +0100 3342465 http://www.medworm.com/index.php?rid=3342464&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007111%2Fabstract%3Frss%3Dyes Purpose: To present importance of EEG in diagnosis of metabolic disease in children during neonatal and infantile period of life. Method: Serial video EEGs were performed in two cases with non-ketotic hyperglycinemia and two newborns with maple syrup urine disease (MSUD). Metabolic investigation of blood, urine and CSF, including genetic analyses were performed. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342464 Mon, 08 Mar 2010 18:13:03 +0100 3342464 http://www.medworm.com/index.php?rid=3342463&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS138824570900710X%2Fabstract%3Frss%3Dyes Purpose: To find some EEG indicators that could differ idiopathic generalized epilepsies (IGE) from partial ones and controls. Methods: The alpha attenuation test (AAT) was applied to the sample of 117 patients with at least one episode of loss of consciousness and 34 controls. All patients underwent EEG recording after one night sleep deprivation. AAT was performed before sleep onset. According to the later established diagnosis, three patients groups were established: 27 with IGE, 34 with partial epilepsy and 56 with unknown cause of loss of consciousness. A total of 36 logarithmic transformed variables underwent the parametric statistical analysis: six relative and six absolute alpha powers from each of the two channels (O2-A1 and O1-A2) after eyes-open (EO) and eyes-closed (EC) condit... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342463 Mon, 08 Mar 2010 18:13:03 +0100 3342463 http://www.medworm.com/index.php?rid=3342462&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007093%2Fabstract%3Frss%3Dyes Purpose: To define the electroencephalographic (EEG) features of symptomatic focal epilepsies caused by temporal lobe tumors. Method: We analyzed EEG features of 20 patients with symptomatic focal epilepsies caused by temporal lobe tumors. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342462 Mon, 08 Mar 2010 18:13:03 +0100 3342462 http://www.medworm.com/index.php?rid=3342461&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007081%2Fabstract%3Frss%3Dyes Malformations of cortical development (MCD) are often recognized as underlying etiology for intractable seizures in children. Prognosis of epilepsy in them is often difficult to predict. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342461 Mon, 08 Mar 2010 18:13:03 +0100 3342461 http://www.medworm.com/index.php?rid=3342460&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS138824570900707X%2Fabstract%3Frss%3Dyes Purpose: To investigate the hyperventilation (HV) effect on quantitative background EEG activity in subjects with mechanical brain injury. Methods: The study was performed on a sample of 69 patients with mechanical brain injury (31 female and 38 male, mean age 45,04 years), 36 of them with posttraumatic epileptic seizures (PTS). Control group consisted of 34 age-matched healthy subjects. Electrodes were positioned according to 10–20 system. Data were processed using program package PERSYST Insight II (Persyst Development Corporation, 1060 Sandreto Drive, Suite E-2, Prescott, AZ 86305). Multiple comparisons of HV effect between control and patient groups, as well as subgroups with and without PTS, were performed with spectral EEG analysis in Laplacian montage. (Source: Clinical Neurophys... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342460 Mon, 08 Mar 2010 18:13:03 +0100 3342460 http://www.medworm.com/index.php?rid=3342459&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007068%2Fabstract%3Frss%3Dyes Purpose: To check which of the two diagnostic tools give better results – Video or EEG? Methods: We used Video system Nicolet One Healthcare Viasys t® with the Sony® camcorder. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342459 Mon, 08 Mar 2010 18:13:03 +0100 3342459 http://www.medworm.com/index.php?rid=3342458&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007056%2Fabstract%3Frss%3Dyes Aim: To study the usefulness of PET and SPECT in clinical practice in dementias. Using numerous specific radiotracers (99mTc-HMPAO, 99mTc-ECD, 18F-FDG, 123J-FP-CIT, 123J-IBZM, 123J-MIBG, 11C-PIB) SPECT or PET can visualize various aspects of brain function in differential diagnosis of dementia: brain perfusion, glucose metabolism, presynaptic and postsynaptic level of dopaminergic system integrity, amyloidal plaque imaging. 18F-FDG PET (cerebral metabolism) and perfusion SPECT are commonly used in clinical practice. Images of Alzheimer’s disease (AD) demonstrate hypometabolism (PET) and hypoperfusion (SPECT) involving especially the posterior cingulate and bilateral parietal and temporal association cortices. Frontotemporal dementia-hypometabolism and hypoperfusion in frontal cortex and ... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342458 Mon, 08 Mar 2010 18:13:03 +0100 3342458 http://www.medworm.com/index.php?rid=3342457&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007044%2Fabstract%3Frss%3Dyes The role of nuclear medicine is functional brain imaging based on two strategies. A first approach is related to brain functional activity and energy metabolism and the second is related to the function of the chemically heterogeneous neurons. SPECT is nuclear medicine technique, presently widely used for imaging of neurovascular disorders, brain tumours, dementia, epilepsy, encephalitis, parkinsonism and various psychiatric diseases. Radiopharmaceuticals developed for SPECT can be categorized into a number of broad categories. Technetium-99m-labeled hexamethylpropyleneamineoxime (Tc-99m-HMPAO), and technetium-99m-labeled ethyl cysteinate dimer (Tc-99m-ECD) are widely used to visualize and to measure cerebral blood flow. 3-[(123)I]iodo-alpha-methyl-l-tyrosine ((I-123-IMT), Thallium-201 chl... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342457 Mon, 08 Mar 2010 18:13:03 +0100 3342457 http://www.medworm.com/index.php?rid=3342456&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007032%2Fabstract%3Frss%3Dyes Aim: To show results of neuroimaging ictal and interictal SPECT in our patients. Method: We performed brain SPECT in four patients with refractory temporal lobe epilepsy. For ictal studies patients had continuous video EEG monitoring. Radiotracer (stabilized 99mTcHMPAO, 740 MBq) injected in the first 30s after seizure onset. For interictal study radiotracer injected when patients have been without seizure. Study was performed 90min after radiotracer injected. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342456 Mon, 08 Mar 2010 18:13:03 +0100 3342456 http://www.medworm.com/index.php?rid=3342455&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007020%2Fabstract%3Frss%3Dyes The knowledge of parameters which describe oxygen and nutrients supply to tissues is essential from standpoint of diagnostics and follow-up of pathologies of brain. Due to their low spatial resolution MR angiographic techniques cannot visualize blood flow inside bulk tissue. In order to obtain the hemodynamic parameters which describe perfusion, MR perfusion imaging use drop in tissue signal during the first pass of contrast agent. Decrease in MR signal is proportional to intravascular concentration of contrast agent, which provides basis for calculation of regional cerebral volume (rCBV), regional cerebral flow (rCBF) and mean transition time (MTT) and corresponding maps of these parameters. Such maps can pinpoint to changes in perfusion of brain tissue which can be consequence or cause o... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342455 Mon, 08 Mar 2010 18:13:03 +0100 3342455 http://www.medworm.com/index.php?rid=3342454&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007019%2Fabstract%3Frss%3Dyes Purpose: The study was designed to evaluate effects of low-frequency rTMS conjugated with partial sleep deprivation in treatment of major depression. Methods: Eleven patients (45±4.6 yrs) with diagnosis of unipolar major depression, unsuccessfully treated, on stable pharmacotherapy were treated with 1Hz rTMS at threshold intensity, over right dorso-lateral prefrontal cortex, during two weeks; 5 trains (60 stimuli per session). Twice during the period of two weeks partial sleep deprivation was applied (4h). Study design comprises active and shamrTMS. Therapeutic effects were estimated by blind rater. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342454 Mon, 08 Mar 2010 18:13:03 +0100 3342454 http://www.medworm.com/index.php?rid=3342453&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007007%2Fabstract%3Frss%3Dyes Purpose: Hereditary motor and sensory neuropathy type 1 (CMT1) is most frequent hereditary neuropathy clinically, neurophysiologically and histopathologically described. Evaluation of parameters changes in all evoked potentials (EP) modalities, depending to CMT1 type. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342453 Mon, 08 Mar 2010 18:13:03 +0100 3342453 http://www.medworm.com/index.php?rid=3342452&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006993%2Fabstract%3Frss%3Dyes Introduction: Central motor conduction time (CMCTM) is recognized as highly reliable indicator in planning neurosurgical treatment. Methods: We have tested 12 patients (48.2±11.4 yrs) with clinical diagnosis of probable cervical myelopathy. For each patient, in addition to conventional neurophysiological tests (SSEP, MEP, EMG, nerve conduction studies), we have calculated root conduction time, with previous calculation of total peripheral conduction time, aiming to define motor conduction exclusively for central motor pathways (CVMPF). TMS was performed on conventional way, as well in position of maximal ante- and retroflexion. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342452 Mon, 08 Mar 2010 18:13:03 +0100 3342452 http://www.medworm.com/index.php?rid=3342451&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006981%2Fabstract%3Frss%3Dyes Introduction: Multimodal evoked potentials (MEP) nowadays often occurs as one of the most supreme neurophysiologic and forensic techniques in head injured patients, and predictional methods in brain function approach. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342451 Mon, 08 Mar 2010 18:13:03 +0100 3342451 http://www.medworm.com/index.php?rid=3342450&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS138824570900697X%2Fabstract%3Frss%3Dyes Transcranial neuromodulation techniques (TNT), repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), are promising treatment methods in neurology and psychiatry. Although, in contrast to DBS in movement disorders or ECT in depression, the efficacy of TNT to treat neurological or psychiatric disorders has not been undoubtedly demonstrated yet, the potential advantages are considerable. TNT techniques avoid surgical risks and provide theoretical advantages of potential specific neural circuit modulation. So far, the most encouraging results have been reported in neuropathic pain and depression. In addition, promising are the results obtained in treatment of epilepsy, parkinsonism, dyskinesia, dystonia, hallucination, and tinnitus. There are i... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342450 Mon, 08 Mar 2010 18:13:03 +0100 3342450 http://www.medworm.com/index.php?rid=3342449&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006968%2Fabstract%3Frss%3Dyes Non-invasive cortical stimulation comprises application of safe and comfortable methods of repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS). Common physiological principles for both methods are founded on prolonged post-interventional effects represented by cortical excitability changes. Patterns of stimulation (frequency, intensity, intervals between consequent trains) are determining direction of excitability changes. Current physiological models suggest predominant activation of cortical interneurons similar to mechanisms of synaptic plasticity, long-term potentiation and long-term depression. This hypothesis is supported by several studies performed on healthy volunteers with administration of CNS active agents with well known effec... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342449 Mon, 08 Mar 2010 18:13:02 +0100 3342449 http://www.medworm.com/index.php?rid=3342448&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006956%2Fabstract%3Frss%3Dyes Purpose: The aim of the present study was to determine the effects of l-NAME, inhibitor of NO synthase, on spike-and-wave discharges (SWD) appearance in homocysteine thiolactone (H)-induced seizures in rats. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342448 Mon, 08 Mar 2010 18:13:02 +0100 3342448 http://www.medworm.com/index.php?rid=3342447&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006944%2Fabstract%3Frss%3Dyes Purpose: The aim of the current study was to examine the influence of L-Arginine, precursor of NO synthase, on seizure susceptibility induced by subconvulsive dose of lindane in rats. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342447 Mon, 08 Mar 2010 18:13:02 +0100 3342447 http://www.medworm.com/index.php?rid=3342446&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006932%2Fabstract%3Frss%3Dyes Purpose: The aim of our study was to investigate the effects of valproate on D,L homocysteine-thiolactone induced seizures in rats. Methods: Adult male Wistar rats were divided into groups: (1) Saline-treated (C, n=10); (2) D,L homocysteine-thiolactone 8mM/kg, i.p. (H, n=7); (3) Valproate i.p. in doses: 50 (V50, n=8), 100 (V100, n=8) and 150mg/kg (V150, n=8) and (4) Valproate (V50,100,150) 30min prior to H (V50H, n=10; V100H, n=10; and V150H, n=8). Seizure behaviour was assessed by incidence, latency, number and intensity of seizure episodes. Seizure severity was determined by a descriptive scale with grades 0–4. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342446 Mon, 08 Mar 2010 18:13:02 +0100 3342446 http://www.medworm.com/index.php?rid=3342445&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006920%2Fabstract%3Frss%3Dyes Purpose: To introduce basic clinical and neurophysiological characteristics in patients with mutation c.94A>G, in Gap Junction Protein ß1 (GJB1), on a gene encoding Connexin32 (Cx32) located on chromosome Xq13.1. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342445 Mon, 08 Mar 2010 18:13:02 +0100 3342445 http://www.medworm.com/index.php?rid=3342444&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006919%2Fabstract%3Frss%3Dyes Electromyoneurography (EMNG) is the method of choice for examination of adult patients with neuromuscular diseases, besides invasive character of EMG muscles examination with needle electrodes. Needle EMG examination includes evaluation of muscles insertional and spontaneous activities (fibrillations, complex repetitive discharges, myotonic discharges etc.), motor unit action potentials recruitment and morphology (amplitude, duration, shape) and ENG evaluation based on motor and sensory conduction velocities values and characteristics of motor and neural potentials. Limitations for EMNG use in adult patients are relatively rare. In patients with acquired neuromuscular diseases with different etiological factors and traumatic injuries of neuromuscular system, EMNG examination is very import... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342444 Mon, 08 Mar 2010 18:13:02 +0100 3342444 http://www.medworm.com/index.php?rid=3342443&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006907%2Fabstract%3Frss%3Dyes The most frequent neuro-muscular (NM) disorders in children are dystrophinopathy, spinal muscular atrophy (SMA) and hereditary neuropathy (HN). Molecular genetic studies are available for most of them. In typical Duchenne-dystrophy and SMA we go directly to genetic diagnostic procedures. In typical HN, we still perform ENMG and then genetic study, because of heterogeneous genotypes with over 40 known genes. “Floppy infants” is syndrome diagnosis with variable etiologies. ENMG is necessary in differentiating the types of NM disorders and sometimes in separating congenital NM dysfunctions from central nervous system dysfunction. With some rare syndromes, like congenital myasthenic syndromes, channalopathies, ENMG test could be very useful before genetic studies. (Source: Clinical Neuroph... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342443 Mon, 08 Mar 2010 18:13:02 +0100 3342443 http://www.medworm.com/index.php?rid=3342442&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006890%2Fabstract%3Frss%3Dyes Although autonomic dysfunction associated with both interictal and ictal epileptogenic activity may have serious consequences, autonomic seizures and autonomic status epilepticus (Aut SE) is a relatively neglected topic. According to a recent definition of an international consortium, autonomic seizures are characterized by prominent alterations of autonomic function. Aut SE is a condition lasting at least 30min and characterized by epileptic activity causing altered autonomic function of any type at seizure onset or in which manifestations consistent with altered autonomic function are prominent (quantitatively dominant or clinically important) even if not present at seizure onset. Aut SE most frequently occurs in otherwise normal child aged 4 and 5 years with Panayiotopoulos syndrome, an... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342442 Mon, 08 Mar 2010 18:13:02 +0100 3342442 http://www.medworm.com/index.php?rid=3342441&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006889%2Fabstract%3Frss%3Dyes The manifestations of dysautonomia in PD and MSA are broad and include gastrointestinal, urogenital, cardiovascular, sudomotor and thermoregulatory symptoms. The aim of our study was to evaluate the degree of dysautonomia in PD and MSA, as well as the usefulness of cardiovascular tests in differentiating parkinsonian syndromes. We evaluated 72 patients with PD and 19 with MSA, as well as 35 age-matched controls. The patients were divided in four groups (de novo patients – group I, patients with controllable PD without therapy complications – group II, patients with complications of levodopa treatment – group III, and MSA patients – group IV). Only orthostatic hypotension test showed statistical significance (p (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342441 Mon, 08 Mar 2010 18:13:02 +0100 3342441 http://www.medworm.com/index.php?rid=3342440&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006877%2Fabstract%3Frss%3Dyes Purpose: To assess autonomic cardiac control in ALS patients and the impact of autonomic dysfunction on outcome. Methods: Fifty five patients with sporadic ALS (28 women, 27 men; average age 56,00±10,34) were compared to 30 healthy controls (17 women, 13 men; average age 42,87±11,91). Ewing‘s cardiovascular reflex tests, short-term power spectrum analysis of heart rate variability (HRV), real time beat-to-beat ECG monitoring with HRV analysis and baroreceptor function analysis (BRS) were performed at the beginning of the study. Cardiovascular responses to 5-min hyperventilation were also assessed. Time domain parameters of HRV were obtained from 24-h ECG monitoring. The follow-up period was 38 months. Kaplan–Meier method and Cox proportional hazard model were used to assess survival... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342440 Mon, 08 Mar 2010 18:13:02 +0100 3342440 http://www.medworm.com/index.php?rid=3342439&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006865%2Fabstract%3Frss%3Dyes According to new data from different studies about connection of heart rate variability and genetical factors is confirmed that there is clear genetical determination of autonomic nervous system status. Regarding to possible existence of constant sympathovagal balance in the basal stage, we made hypothesis that the matching of the drug and dose of every disease treatment depend of the type of sympathovagal balance. The goal of research was to use this methodology in the testing of patients with myocardial infarction, hypertension, syncopes and healthy persons. The patients were divided in two clear groups related to predominance of sympaticus or vagus with subgroups with moderate and strong activity. The groups were created according to normal values from tables. After the follow up of pat... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342439 Mon, 08 Mar 2010 18:13:02 +0100 3342439 http://www.medworm.com/index.php?rid=3342438&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006853%2Fabstract%3Frss%3Dyes The knowledge of parameters which describe oxygen and nutrients supply to tissues is essential from standpoint of diagnostics and follow-up of pathologies of brain. Due to their low spatial resolution MR angiographic techniques cannot visualize blood flow inside bulk tissue. MR perfusion imaging is technique which use drop in tissue signal during the first pass of contrast agent in order to obtain the haemodynamic parameters which describe perfusion. Calculation of those values requires determination of time course of change of agent concentration in both tissue and feeding artery. Decrease in MR signal is proportional to intravascular concentration of contrast agent, which provides basis for calculation of regional cerebral volume (rCBV), regional cerebral flow (rCBF) and mean transition ... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342438 Mon, 08 Mar 2010 18:13:02 +0100 3342438 http://www.medworm.com/index.php?rid=3342437&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006841%2Fabstract%3Frss%3Dyes The “Guidelines for diagnosis and treatment of chronic autoimmune neuropathies” was developed by the Medical Advisory Board of the Neuropathy Association as an aid to the management of patients with peripheral neuropathy. The chronic autoimmune neuropathies (CAN) are a diverse group of syndromes that result from immune-mediated damage to the peripheral nerves. For many of these disorders, there is a lack of definitive diagnostic tests, and a paucity of controlled therapeutic trials. Consequently, the diagnosis can be missed, and the patients remain untreated. The information presented in this paper is intended to help physicians recognize these disorders and provide the appropriate treatments. The guidelines include classification of the CAN, their clinical presentations, associated el... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342437 Mon, 08 Mar 2010 18:13:02 +0100 3342437 http://www.medworm.com/index.php?rid=3342436&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS138824570900683X%2Fabstract%3Frss%3Dyes The diagnosis of brain death (BD) relies on prerequisites (the cause of coma must be identified and be sufficient to produce BD), on the clinical evaluation (non-reactive coma, loss of brainstem reflexes, apnea), and on confirmatory tests, which can be subdivided into neurophysiological tests (electroencephalogram: EEG, evoked potentials: EPs) and assessment of brain circulation (four-vessel angiography, radioisotopic techniques, intracranial Doppler). Clinical neurophysiology has sometimes been reproached not to provide assessment of the whole brain. It should be mentioned that the same reproach can be heaped on all other diagnostic methods, including clinical examination and angiographic techniques. This argumentation underlines the flaws of a purely phenomenological approach of BD. We a... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342436 Mon, 08 Mar 2010 18:13:02 +0100 3342436 http://www.medworm.com/index.php?rid=3342435&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006828%2Fabstract%3Frss%3Dyes The aim of treatment of epilepsies is to control seizures without causing adverse effects by reaching the best possible quality of life. For this aim diagnostic and therapeutic monitoring became an increasingly clinically important tool because seizures are transient events difficult to observe. An assessment of the amount of knowledge gain by the different examination methods such as routine EEG, sleep EEG, ictal routine EEG, long-term video EEG. Evaluation of antiepileptic drugs can be performed with the aid of therapeutic intensive seizure analysis including neuropsychological testing. Computer supported seizure detection in emergency cases status epilepticus and for the quantification of frequency and severity of epileptic seizures in difficult to treat epilepsies. Here adequate method... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342435 Mon, 08 Mar 2010 18:13:02 +0100 3342435 http://www.medworm.com/index.php?rid=3342434&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006373%2Fabstract%3Frss%3Dyes We present a case of isolated median thenar branch palsy due to brachial neuritis. The patient presented with painless thumb weakness without sensory loss. Nerve conduction studies showed severe distal median nerve motor dysfunction with active and chronic denervation of abductor pollicis brevis and opponens pollicis on electromyography. The remainder of the study was normal. Motor and somatosensory evoked potentials ruled out a proximal lesion. Magnetic resonance imaging did not reveal a compressive aetiology. Clinical and electrophysiologic improvement occurred over the next year with no intervention. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342434 Mon, 08 Mar 2010 18:13:01 +0100 3342434 http://www.medworm.com/index.php?rid=3342433&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006361%2Fabstract%3Frss%3Dyes Objective: We used transcranial magnetic stimulation (TMS) to determine whether there are variations in cortical excitability associated with the menstrual cycle in women with new onset untreated epilepsy. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342433 Mon, 08 Mar 2010 18:13:01 +0100 3342433 http://www.medworm.com/index.php?rid=3342432&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS138824570900635X%2Fabstract%3Frss%3Dyes Objective: We used transcranial magnetic stimulation (TMS) to study the in vivo effect of recurrent seizures on cortical excitability during the evolution of chronic epilepsy. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342432 Mon, 08 Mar 2010 18:13:01 +0100 3342432 http://www.medworm.com/index.php?rid=3342431&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006348%2Fabstract%3Frss%3Dyes Background: It is not routine practice in Australia for comatose ICU patients to have continuous EEG monitoring. These patients are at significant risk of developing subclinical seizures including status epilepticus. The technical demands required for standard 10/20 EEG system severely limit its application for ICU monitoring. We undertook a pilot study to optimise the 2-channel EEG system in detecting seizures demonstrable on 10/20 system, as lead up to a prospective study of its utility in continuous ICU EEG monitoring. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342431 Mon, 08 Mar 2010 18:13:01 +0100 3342431 http://www.medworm.com/index.php?rid=3342430&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006336%2Fabstract%3Frss%3Dyes Objective: Nerve conduction studies are commonly requested for children with pes cavus, to exclude possible underlying neuropathy. We aimed to review our experience and identify predictive factors for abnormal neurophysiologic testing in these children. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342430 Mon, 08 Mar 2010 18:13:01 +0100 3342430 http://www.medworm.com/index.php?rid=3342429&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006324%2Fabstract%3Frss%3Dyes This study assessed the sensitivity of NCS and MRI in diagnosing UNE. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342429 Mon, 08 Mar 2010 18:13:01 +0100 3342429 http://www.medworm.com/index.php?rid=3342428&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006312%2Fabstract%3Frss%3Dyes Objective: To determine whether there is disruption of energy dependent processes and axonal depolarization during the development of stroke-like episodes in MELAS (Mitochondrial myopathy, Encephalopathy, Lactic Acidosis and Stroke-like episodes). (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342428 Mon, 08 Mar 2010 18:13:01 +0100 3342428 http://www.medworm.com/index.php?rid=3342427&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006300%2Fabstract%3Frss%3Dyes Introduction: Oxaliplatin, a platinum-based chemotherapy utilised in the treatment of colorectal cancer, produces prominent dose-limiting neurotoxicity. Acute neurotoxicity develops immediately following infusion and resolves within days, while chronic neuropathy develops with higher cumulative doses. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342427 Mon, 08 Mar 2010 18:13:01 +0100 3342427 http://www.medworm.com/index.php?rid=3342426&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006294%2Fabstract%3Frss%3Dyes HIV infection is associated with several forms of peripheral neuropathy, the most common being a distal sensory polyneuropathy, either from HIV viral infection or antiretroviral drug therapy. Mechanisms of disease remain incompletely understood with some evidence implicating envelope glycoprotein gp120 mediated neuronal apoptosis for the former, and mitochondrial toxicity±DNA polymerase gamma involvement in the latter. We studied 16 HIV positive patients, 14 of whom had neuropathy (10 HIV infection alone, 4 drug related). Clinically neuropathic patients were all symptomatic and had abnormalities in nerve conduction studies (13), and thermal quantitative sensory testing (11). Heart rate variability was abnormal in 4 patients in at least 1 of 3 parameters. Using the Qtrac Trond protocol, th... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342426 Mon, 08 Mar 2010 18:13:01 +0100 3342426 http://www.medworm.com/index.php?rid=3342425&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006282%2Fabstract%3Frss%3Dyes BPPV can sometimes prove resistant to conventional treatment. This may relate to physical limitations, multi canal pathology or cupulithiasis (otoconia which is stuck). In our clinic we now have the ability to treat these patients using the Epley Omniax Rotator. This device allows the patient to be rotated in any axis with no effort required for either subject or staff. Eye movements are recorded using an infrared camera. Computer analysis of the nystagmus assists with the accurate diagnosis of the BPPV type to facilitate effective treatment. Since December 2008 we have attended to 86 cases. Fifty of these had canalithiasis with seven affecting the lateral canal one in the anterior and 42 in the posterior. 15 of these cases had cupulolithiasis with 12 having it in the lateral canal, two in... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342425 Mon, 08 Mar 2010 18:13:01 +0100 3342425 http://www.medworm.com/index.php?rid=3342424&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006270%2Fabstract%3Frss%3Dyes The pathophysiology of Amyotrophic Lateral Sclerosis (ALS) is not entirely understood, although 5–10% of cases are familial with the remainder termed sporadic. While there have been case reports of ALS developing following electrical trauma, a recent systematic review suggested that there was no convincing evidence for a causal relationship. Herein, we describe a 25-year-old male patient who developed ALS with initial onset in the right upper limb, soon after sustaining a severe electrical injury to the same region, associated with the development of structural abnormalities involving the motor pathways evident on magnetic resonance imaging. Assessment of cortical excitability with transcranial magnetic stimulation demonstrated a relatively inexcitable motor cortex, with a significant in... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342424 Mon, 08 Mar 2010 18:13:01 +0100 3342424 http://www.medworm.com/index.php?rid=3342423&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006269%2Fabstract%3Frss%3Dyes Lambert–Eaton myasthenic syndrome (LEMS) is thought to be an extremely rare disorder of the neuromuscular junction, and it is thought that many cases succumb from underlying malignancy. There are a number of potential pitfalls in making the diagnosis, and LEMS is frequently missed, whereupon the patient is assumed to have a myopathy as the cause of proximal weakness, or a neuropathy if hyporeflexia and autonomic features are predominant. The post exercise CMAP test for this disorder is extremely easy, safe and quick, but it will only be positive if the test is actually done. Specific therapy with 3,4 diaminopyridine±pyridostigmine is very effective. An immune versus tumour effect is reasonably well substantiated – this means that survival is longer or long term, and also suggests that... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342423 Mon, 08 Mar 2010 18:13:01 +0100 3342423 http://www.medworm.com/index.php?rid=3342422&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007834%2Fabstract%3Frss%3Dyes Conclusions: Findings suggest that presence vs. absence of cerebellar signs (intention tremor) in ET results in differential affection of volitional preparatory motor cortical activity. The BP increase in ETPT may indicate compensatory activity, whereas the widespread centro-parietal BP reduction in ETIT suggests dysfunction of the cerebello-dentato-thalamo-cortical projection.Significance: Reduction of the late BP amplitude may serve as a surrogate marker for dysfunction of the cerebello-dentato-thalamo-cortical projection in ET. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342422 Mon, 08 Mar 2010 18:13:00 +0100 3342422 http://www.medworm.com/index.php?rid=3342421&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007809%2Fabstract%3Frss%3Dyes Conclusions: Data normalised to Mmax better reflect the motoneurone recruitment after SICI. To enhance reproducibility, MEP should be normalised to Mmax. This adjusts for some of the non-linear properties at the spinal, and possibly, at cortical levels.Significance: To reduce variability is important because TMS is becoming widely adopted and is being used in patients. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342421 Mon, 08 Mar 2010 18:13:00 +0100 3342421 http://www.medworm.com/index.php?rid=3342420&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007585%2Fabstract%3Frss%3Dyes Conclusions: Thirtyminutes of mobile phone exposure has no significant short-term effect on the inhibitory control of saccades.Significance: The cortical processing responsible for saccade inhibition is not affected by exposure to EMF emitted by a mobile phone. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342420 Mon, 08 Mar 2010 18:13:00 +0100 3342420 http://www.medworm.com/index.php?rid=3342419&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007780%2Fabstract%3Frss%3Dyes Conclusions: Low frequency stimulation increases intracortical inhibition and occludes LTP- and LTD-like plasticity in the human motor cortex.Significance: This finding supports the concept that metaplasticity in the human motor cortex follows similar rules as metaplasticity in in vitro experiments. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342419 Mon, 08 Mar 2010 18:13:00 +0100 3342419 http://www.medworm.com/index.php?rid=3342418&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007925%2Fabstract%3Frss%3Dyes Conclusions: The somatosensory evoked magnetic fields waveforms elicited by the two tactile stimuli (tactile-on and tactile-off stimuli) with a mechanical stimulator were strikingly similar. These mechanical stimuli elicited both contralateral SI and ipsilateral SII activities.Significance: Tactile stimulation with a mechanical stimulator provides new possibilities for experimental designs in studies of the human mechanoreceptor system. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342418 Mon, 08 Mar 2010 18:13:00 +0100 3342418 http://www.medworm.com/index.php?rid=3342417&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007810%2Fabstract%3Frss%3Dyes Conclusion: These findings show that P-ICA can be used to dissect effectively sensory ERPs into physiologically meaningful components, and indicate a new approach for exploring the effect of various experimental modulations of sensory ERPs.Significance: This approach offers a better understanding of the functional significance of sensory ERPs. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342417 Mon, 08 Mar 2010 18:13:00 +0100 3342417 http://www.medworm.com/index.php?rid=3342416&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007500%2Fabstract%3Frss%3Dyes Conclusions: The changes in the timing and magnitude of early-latency ERPs likely reflect brain maturational processes. The age-related changes to auditory stimuli generally occurred later than those to visual stimuli suggesting that visual processing matures faster than auditory processing.Significance: ERPs may be used to assess children’s cognitive development in rural areas of Africa. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342416 Mon, 08 Mar 2010 18:13:00 +0100 3342416 http://www.medworm.com/index.php?rid=3342415&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007433%2Fabstract%3Frss%3Dyes Conclusions: Using our normal data, the computed lower limits of the 95% prediction interval for the sural SNAP amplitude of an individual subject, depending on his age and height, were calculated.Significance: The individualized normal values provided by our equation are essential for the correct interpretation of sural nerve studies. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342415 Mon, 08 Mar 2010 18:13:00 +0100 3342415 http://www.medworm.com/index.php?rid=3342414&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007871%2Fabstract%3Frss%3Dyes Conclusions: By using ROC derived cutoff-points, DSST could accurately discriminate MG patients from control subjects. Quantitative results of our study are limited by small series of patients and can vary with larger series. However we think that the difference between the decremental response patterns of patients and controls is a valuable finding.Significance: DSST can be a sensitive, specific and non-invasive choice in the patients who have high suspicion for MG but normal conventional RNS. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342414 Mon, 08 Mar 2010 18:13:00 +0100 3342414 http://www.medworm.com/index.php?rid=3342413&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007482%2Fabstract%3Frss%3Dyes Conclusions: In JP, functional deficits and pathological oscillations appear coincidentally reduced following administration of low-dose zolpidem.Significance: GABA(A) alpha-1 sensitive desynchronisation of pathological oscillations may represent a biomarker and potential therapeutic target in brain injury. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342413 Mon, 08 Mar 2010 18:12:59 +0100 3342413 http://www.medworm.com/index.php?rid=3342412&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007792%2Fabstract%3Frss%3Dyes Conclusions: Greater intra and inter hemispheric fluctuations of ASSR gamma band phase synchronization in Sz add to previous studies suggesting timing deficiencies within neural populations, possibly caused by impairments of neural network parameters.Significance: This study provides experimental support that may aid in understanding the dynamics of neural phase synchrony caused by modifications of underlying neurotransmitter systems, as reflected in disease states such as schizophrenia. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342412 Mon, 08 Mar 2010 18:12:59 +0100 3342412 http://www.medworm.com/index.php?rid=3342411&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007883%2Fabstract%3Frss%3Dyes Conclusions: The underadditivity of the MMN responses suggests that vowel and pitch differences are processed by interacting neural networks.Significance: The results indicate that vowel and pitch are processed as integrated units, even at a pre-attentive level. Music-processing specificity thus rests on more complex dimensions of music and speech. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342411 Mon, 08 Mar 2010 18:12:59 +0100 3342411 http://www.medworm.com/index.php?rid=3342410&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007524%2Fabstract%3Frss%3Dyes Conclusions: The MMNm is followed by a sustained deviance response in the oddball paradigm. While some characteristics of the response coincide with the sustained field, its growth with tone duration differs. The response could possibly be related to automatic orienting of attention, but further studies are required to explore its functional role.Significance: The sustained deviance response is a separate component – distinct from the MMNm and P3 – that needs to be considered in the evaluation of data obtained with the auditory oddball paradigm. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342410 Mon, 08 Mar 2010 18:12:59 +0100 3342410 http://www.medworm.com/index.php?rid=3342409&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007512%2Fabstract%3Frss%3Dyes Conclusions: With this study, the viability of the paradigm was shown for healthy participants and will next be evaluated with individuals diagnosed with ALS or locked-in syndrome (LIS) after stroke.Significance: The here presented BCI offers communication with binary choices (yes/no) independent of vision. As it requires only little time per selection, it may constitute a reliable means of communication for patients who lost all motor function and have a short attention span. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342409 Mon, 08 Mar 2010 18:12:59 +0100 3342409 http://www.medworm.com/index.php?rid=3342408&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007469%2Fabstract%3Frss%3Dyes Conclusions: The dynamics of activities corresponding to the two conditions disclose a spread of activation from posterior lateral frontal in the “maintained condition” to anterior medial frontal in the “shifted condition”.Significance: These results are consistent with fMRI results concerning the major involvement of medial frontal cortex in tasks involving reasoning and choice making. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342408 Mon, 08 Mar 2010 18:12:59 +0100 3342408 http://www.medworm.com/index.php?rid=3342407&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007858%2Fabstract%3Frss%3Dyes Conclusions: Free copper appears to be a player in cognitive decline.Significance: This evidence suggests the need for a shift of focus from total to free copper levels in the study of mental decline and sustains the notion that free copper may be a risk factor in the development of impaired cognition. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342407 Mon, 08 Mar 2010 18:12:59 +0100 3342407 http://www.medworm.com/index.php?rid=3342406&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007421%2Fabstract%3Frss%3Dyes Conclusions: The present results support the view that MEP and Rolandic beta oscillation amplitudes are associated with motor cortical excitability. However, oscillations seen in EEG reflect the excitability of a large population of cortical neurons, and MEP amplitude is affected also by spinal excitability and action potential desynchronization. Thus, MEP and EEG oscillation amplitudes are not strongly correlated. In addition, even during rest, motor system excitability appears to be related to activity in occipital areas at frequency ranges associated with visuomotor processing.Significance: The ability of spontaneous oscillations and MEPs to inform us about cortical excitability is clarified. For example, it is suggested that oscillatory activity at non-motor sites might be related to m... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342406 Mon, 08 Mar 2010 18:12:59 +0100 3342406 http://www.medworm.com/index.php?rid=3342405&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007561%2Fabstract%3Frss%3Dyes Conclusions: These results confirmed that compared with non-athletes, elite athletes are characterized by a reduced cortical activation during simple voluntary movement.Significance: Cortical alpha rhythms are implicated in the “neural efficiency” of athletes’ motor systems. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342405 Mon, 08 Mar 2010 18:12:59 +0100 3342405 http://www.medworm.com/index.php?rid=3342404&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007743%2Fabstract%3Frss%3Dyes Conclusions: These results suggested that the hyperexcitability in the thalamocortical pathway were responsible for this condition. Hyperexcitability was presumably caused by the influence of the corticothalamic feedback and the neural interactions between the relay neurons and the reticular neurons. The clinically significant finding was that an increasing amplitude of N20 thus indicated the presence of a sub-clinical change.Significance: A brain tumour could increase the amplitude of N20 due to the hyperexcitability in the thalamocortical pathway. An increasing amplitude of N20 thus indicated the presence of a sub-clinical change in the thalamocortical pathway on the side of the tumour. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342404 Mon, 08 Mar 2010 18:12:58 +0100 3342404 http://www.medworm.com/index.php?rid=3342403&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006695%2Fabstract%3Frss%3Dyes Abstract: Repetitive transcranial magnetic stimulation (rTMS) of the human motor cortex can produce long-lasting changes in the excitability of the motor cortex to single pulse transcranial magnetic stimulation (TMS). rTMS may increase or decrease motor cortical excitability depending critically on the characteristics of the stimulation protocol. However, it is still poorly defined which mechanisms and central motor circuits contribute to these rTMS induced long-lasting excitability changes. We have had the opportunity to perform a series of direct recordings of the corticospinal volley evoked by single pulse TMS from the epidural space of conscious patients with chronically implanted spinal electrodes before and after several protocols of rTMS that increase or decrease brain excitability.... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342403 Mon, 08 Mar 2010 18:12:58 +0100 3342403 http://www.medworm.com/index.php?rid=3342402&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007779%2Fabstract%3Frss%3Dyes Within the past two decades a wide range of transcranial stimulation protocols have been introduced to induce plasticity in the human primary motor cortex (M1) (). Two stimulation techniques are currently available which have different mechanisms of action. Transcranial magnetic stimulation (TMS) induces a fast time-varying electrical current in M1. When the induced current exceeds threshold intensity, TMS can elicit action potentials in corticospinal neurons and produce a motor evoked potential (MEP) in the target muscle (). During transcranial direct current stimulation (TDCS), a weak DC current is continuously applied to the human cortex via electrodes attached to the scalp (). In contrast to TMS, the direct current passing through the cortex is too weak to elicit action potentials in c... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342402 Mon, 08 Mar 2010 18:12:58 +0100 3342402 http://www.medworm.com/index.php?rid=3342401&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007846%2Fabstract%3Frss%3Dyes The copper in the blood can be viewed as in two pools, one covalently bound to ceruloplasmin (Cp), which accounts for 85–95% of blood copper in normal humans, and the other more loosely bound to albumin and small molecules, which accounts for the remainder. The term “free copper” has been applied to this second pool. The amount of this nonceruloplasmin bound copper, or free copper, is calculated by subtracting the amount of copper in ceruloplasmin from the total serum copper. The amount of ceruloplasmin is determined either immunologically or enzymatically, and the amount of copper in the ceruloplasmin then calculated. While the “free copper” is loosely bound and not really free, it is more “freely” available to meet cellular needs, and also to cause potential toxicity if it ... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342401 Mon, 08 Mar 2010 18:12:58 +0100 3342401 http://www.medworm.com/index.php?rid=3342400&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245710000982%2Fabstract%3Frss%3Dyes (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342400 Mon, 08 Mar 2010 18:12:58 +0100 3342400 http://www.medworm.com/index.php?rid=3342399&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245710000970%2Fabstract%3Frss%3Dyes (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342399 Mon, 08 Mar 2010 18:12:58 +0100 3342399 http://www.medworm.com/index.php?rid=3342398&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245710000933%2Fabstract%3Frss%3Dyes (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342398 Mon, 08 Mar 2010 18:12:58 +0100 3342398 http://www.medworm.com/index.php?rid=3342397&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245710000921%2Fabstract%3Frss%3Dyes (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3342397 Mon, 08 Mar 2010 18:12:58 +0100 3342397 http://www.medworm.com/index.php?rid=3350885&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207581%26dopt%3DAbstract CONCLUSIONS: The MMN can be recorded even without the standard stimulus, as an accurate memory trace is constructed for the invariant features of the auditory input. SIGNIFICANCE: Omitting the standard stimuli results in almost 50% shorter recording time and the larger selection of deviant types with the newly introduced brightness, density, and noise-level changes provides even more information on the individual perceptual profiles than conventional multi-feature paradigms. PMID: 20207581 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3350885 Fri, 05 Mar 2010 00:00:00 +0100 3350885 http://www.medworm.com/index.php?rid=3350886&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207193%26dopt%3DAbstract Authors: Halmagyi GM, Carey JP PMID: 20207193 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3350886 Thu, 04 Mar 2010 00:00:00 +0100 3350886 http://www.medworm.com/index.php?rid=3338962&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20202896%26dopt%3DAbstract Authors: Todd NP PMID: 20202896 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3338962 Tue, 02 Mar 2010 00:00:00 +0100 3338962 http://www.medworm.com/index.php?rid=3338961&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20202897%26dopt%3DAbstract CONCLUSIONS: Abnormal VEMPs may be produced not only by peripheral vestibulopathy but also by brainstem lesions. VEMPs may be influenced by effects caused by lesions located above the level of the vestibular nuclei. SIGNIFICANCE: This study adds to the knowledge of anatomical brainstem representation of VEMP. PMID: 20202897 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3338961 Tue, 02 Mar 2010 00:00:00 +0100 3338961 http://www.medworm.com/index.php?rid=3338960&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20202898%26dopt%3DAbstract Authors: Wijnen VJ, van Boxtel GJ PMID: 20202898 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3338960 Tue, 02 Mar 2010 00:00:00 +0100 3338960 http://www.medworm.com/index.php?rid=3338959&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20202899%26dopt%3DAbstract CONCLUSIONS: Irrespective of their clinical assessment, a few patients are likely to process sound deviance (MMN) or novelty (nP3), mainly when their state is not due to anoxia. SIGNIFICANCE: Some PVS patients may be able to put certain awareness marker processes to work. The diagnostic criteria for PVS or MCS, currently based on mere behaviour, should also include functional brain investigations, such as ERPs, related to the aetiology. PMID: 20202899 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3338959 Tue, 02 Mar 2010 00:00:00 +0100 3338959 http://www.medworm.com/index.php?rid=3338958&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20202900%26dopt%3DAbstract CONCLUSIONS: This finding may represent that the operation of SI is extended to the post-movement period, perhaps as a compensatory mechanism for preventing unwanted movement in surrounding muscles. SIGNIFICANCE: While many types of impaired inhibition have been described previously in PKD, this is the first possible example of increased inhibition. PMID: 20202900 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3338958 Tue, 02 Mar 2010 00:00:00 +0100 3338958 http://www.medworm.com/index.php?rid=3338957&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20202901%26dopt%3DAbstract CONCLUSIONS: During an MD attack, dynamic utricular function in the affected ear as measured by the n10 of the oVEMP to 500Hz Fz BCV is enhanced, whereas dynamic saccular function in the affected ear as measured by the p13 of the cVEMP to 500Hz Fz BCV is not similarly affected. SIGNIFICANCE: The MD attack appears to affect different otolithic regions differentially. PMID: 20202901 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3338957 Tue, 02 Mar 2010 00:00:00 +0100 3338957 http://www.medworm.com/index.php?rid=3338963&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20199888%26dopt%3DAbstract Authors: Kuwabara S PMID: 20199888 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3338963 Mon, 01 Mar 2010 00:00:00 +0100 3338963 http://www.medworm.com/index.php?rid=3323394&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194049%26dopt%3DAbstract Authors: Finsterer J PMID: 20194049 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3323394 Sat, 27 Feb 2010 00:00:00 +0100 3323394 http://www.medworm.com/index.php?rid=3323397&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20188625%26dopt%3DAbstract CONCLUSIONS: The experience of phosphenes during tACS involving the visual cortex is influenced by volume conductions effects of the scalp. SIGNIFICANCE: Retinal effects should be taken into account when studying the cortical modulatory effects of tACS. PMID: 20188625 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3323397 Wed, 24 Feb 2010 00:00:00 +0100 3323397 http://www.medworm.com/index.php?rid=3323396&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20188626%26dopt%3DAbstract CONCLUSIONS: In PS all cerebral locations are able to spontaneously and independently generate and propagate interictal spikes, indicating that PS is a multifocal epileptic syndrome. SIGNIFICANCE: Confirmation of the multifocal character of PS improves clinical diagnosis and challenges our current taxonomic concepts by expanding the anatomical boundaries of a distinct focal epilepsy phenotype from lobar to system. PMID: 20188626 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3323396 Wed, 24 Feb 2010 00:00:00 +0100 3323396 http://www.medworm.com/index.php?rid=3323395&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20188627%26dopt%3DAbstract CONCLUSIONS: Motivation modulates the P300 amplitude in an ERP-BCI. SIGNIFICANCE: Motivation may contribute to variance in BCI performance and should be monitored in BCI settings. PMID: 20188627 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3323395 Wed, 24 Feb 2010 00:00:00 +0100 3323395 http://www.medworm.com/index.php?rid=3314855&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20185361%26dopt%3DAbstract CONCLUSIONS: The Hi-Ob-Db is a clinical scale which correlates with the neurophysiological impairment of the median nerve and with patient-oriented findings in patients with CTS. SIGNIFICANCE: The new scale may be useful in routine examination and for scientific purposes. PMID: 20185361 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314855 Tue, 23 Feb 2010 00:00:00 +0100 3314855 http://www.medworm.com/index.php?rid=3314854&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20185362%26dopt%3DAbstract CONCLUSION: Continuous pain in CRPS is associated with attenuated motor cortex reactivity. SIGNIFICANCE: Abnormal motor cortex reactivity may be linked with motor dysfunction of the affected hand in CRPS. PMID: 20185362 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314854 Tue, 23 Feb 2010 00:00:00 +0100 3314854 http://www.medworm.com/index.php?rid=3314853&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20185363%26dopt%3DAbstract CONCLUSION: Antidromic stimulation of the MPPDN at a distance of 8-10cm from the medial side of the first metatarsal head of the great toe yields in reliable SNAP responses. SIGNIFICANCE: This technique should be useful in the evaluation of the MPPDN involvement in Joplin's neuroma. PMID: 20185363 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314853 Tue, 23 Feb 2010 00:00:00 +0100 3314853 http://www.medworm.com/index.php?rid=3314852&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20185364%26dopt%3DAbstract CONCLUSION: Our results confirm that physiological tremor can be voluntarily reduced, and this reduction is bilateral. The modulation attempt did not however increase the frequency relationship between both sides. SIGNIFICANCE: A central command aiming at modulating tremor amplitude will not increase the synchronization between oscillators responsible for the central components of physiological tremor. PMID: 20185364 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314852 Tue, 23 Feb 2010 00:00:00 +0100 3314852 http://www.medworm.com/index.php?rid=3314851&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20185365%26dopt%3DAbstract Authors: Richardson M Brain scanning methods were first applied in patients with epilepsy more than 30years ago. A very substantial literature now exists in this field, which is exponentially increasing. Contemporary neuroimaging studies in epilepsy reflect new concepts in the epilepsies, as well as current methodological developments. In particular, this area is emphasising the role of networks in epileptogenicity, the existence of dynamic phenomena which can be captured by imaging, and is beginning to validate the implementation of neuroimaging in the clinic. Here, recent studies of the last 5years are reviewed, covering the full range of neuroimaging methods with SPECT, PET and MRI in epilepsy. PMID: 20185365 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314851 Tue, 23 Feb 2010 00:00:00 +0100 3314851 http://www.medworm.com/index.php?rid=3314864&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181513%26dopt%3DAbstract CONCLUSIONS: EEG activity in the theta band is increased in anatomically meaningful patterns in PE patients, which differs from the anatomical distribution of theta in healthy persons. SIGNIFICANCE: The findings contribute to our understanding of the sources of theta rhythms and the pathophysiology of PE. PMID: 20181513 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314864 Mon, 22 Feb 2010 00:00:00 +0100 3314864 http://www.medworm.com/index.php?rid=3314863&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181514%26dopt%3DAbstract Authors: Paulus W PMID: 20181514 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314863 Mon, 22 Feb 2010 00:00:00 +0100 3314863 http://www.medworm.com/index.php?rid=3314862&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181515%26dopt%3DAbstract CONCLUSIONS: Muscle membranes in the patients were chronically depolarized by hyperkalemia. Whereas dialysis transiently normalized muscle membrane potential, it was not adequate to normalize t-tubule function. SIGNIFICANCE: Chronic muscle membrane depolarization by hyperkalemia may account for some of the functional deficits in uremic myopathy. Consistent normalization of membrane potential by avoiding hyperkalemia may therefore reduce symptoms of 'uremic myopathy'. PMID: 20181515 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314862 Mon, 22 Feb 2010 00:00:00 +0100 3314862 http://www.medworm.com/index.php?rid=3314861&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181516%26dopt%3DAbstract Authors: Curthoys IS PMID: 20181516 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314861 Mon, 22 Feb 2010 00:00:00 +0100 3314861 http://www.medworm.com/index.php?rid=3314860&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181517%26dopt%3DAbstract CONCLUSIONS: The electrophysiologic findings associated with OPMD are similar to changes noted in other dystrophic diseases. These findings argue against an association between OPMD and peripheral neuropathy. SIGNIFICANCE: OPMD may not be associated with a peripheral neuropathy, as has been previously suggested. PMID: 20181517 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314860 Mon, 22 Feb 2010 00:00:00 +0100 3314860 http://www.medworm.com/index.php?rid=3314859&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181518%26dopt%3DAbstract CONCLUSIONS: We recommend the baseline-adjusted area under the curve for scoring the magnitude of the nociceptive blink reflex and the peak z score to define the nociceptive blink reflex threshold. SIGNIFICANCE: The here defined standardized criteria to score blink reflex magnitude and threshold improve the comparability and validity of blink reflex studies. PMID: 20181518 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314859 Mon, 22 Feb 2010 00:00:00 +0100 3314859 http://www.medworm.com/index.php?rid=3314858&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181519%26dopt%3DAbstract Authors: Krishnan AV PMID: 20181519 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314858 Mon, 22 Feb 2010 00:00:00 +0100 3314858 http://www.medworm.com/index.php?rid=3314857&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181520%26dopt%3DAbstract CONCLUSIONS: NC patients showed an increased sympathetic drive on heart rate (HR) in the supine condition that did not further increase during HUTT. SIGNIFICANCE: These results suggest the proper functioning of cardiovascular reflexes in NC but support an impairment of HR modulation at rest in favour of an enhanced sympathetic activity. PMID: 20181520 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314857 Mon, 22 Feb 2010 00:00:00 +0100 3314857 http://www.medworm.com/index.php?rid=3314856&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20181521%26dopt%3DAbstract CONCLUSIONS: EEG may be of prognostic value for spontaneous neurological improvement, early neurological deterioration and death in the acute setting of acute anterior circulation syndrome of presumed ischemic origin. SIGNIFICANCE: These findings may have an impact on stroke care. PMID: 20181521 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3314856 Mon, 22 Feb 2010 00:00:00 +0100 3314856 http://www.medworm.com/index.php?rid=3273339&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153686%26dopt%3DAbstract CONCLUSIONS: Our findings suggest that the epidural C2 triphasic wave is a potential arising from DCN. The low-frequency epidural SEP component is subtended by a 1200Hz HFO, probably generated by post-synaptic events. SIGNIFICANCE: The amplitude reduction of the DCN response during movement is possibly due to decreased excitability of the DCN neurons receiving the somatosensory ascending input. PMID: 20153686 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273339 Thu, 11 Feb 2010 00:00:00 +0100 3273339 http://www.medworm.com/index.php?rid=3273338&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153687%26dopt%3DAbstract Authors: Tankisi H, Terkelsen AJ, Fuglsang-Frederiksen A PMID: 20153687 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273338 Thu, 11 Feb 2010 00:00:00 +0100 3273338 http://www.medworm.com/index.php?rid=3273337&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153688%26dopt%3DAbstract CONCLUSIONS: This study of a large prospective sample provides evidence for the association of alpha-delta sleep with subjective sensation of light sleep and with sleep time underestimation. SIGNIFICANCE: Alpha-delta sleep may be a marker of the physiological disorder underlying light sleep and sleep state misperception. PMID: 20153688 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273337 Thu, 11 Feb 2010 00:00:00 +0100 3273337 http://www.medworm.com/index.php?rid=3273336&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153689%26dopt%3DAbstract CONCLUSIONS: EEG electrophysiological patterns and epileptogenic susceptibility differ in Z-RTT according to the level of performance (i.e. HIP or LP). SIGNIFICANCE: These results indicate that HIP and LP Z-RTT should be considered as distinct entities, not only on a clinical basis, but also as it concerns EEG features and epileptogenic susceptibility. These results could offer support in the practical management of patients and family counseling. PMID: 20153689 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273336 Thu, 11 Feb 2010 00:00:00 +0100 3273336 http://www.medworm.com/index.php?rid=3273335&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153690%26dopt%3DAbstract CONCLUSIONS: The results indicate that intramuscular administration of glutamate and capsaicin induces muscle pain which has the potential to perturb some normal jaw motor functions. SIGNIFICANCE: The present findings suggest that peripheral glutamate and capsaicin receptor mechanisms interact to affect some jaw motor as well as sensory (i.e. pain) functions and provide new insights into the complexity of orofacial pain. Management approaches that target the peripheral nervous system and receptor mechanisms may prevent such changes in jaw motor function. PMID: 20153690 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273335 Thu, 11 Feb 2010 00:00:00 +0100 3273335 http://www.medworm.com/index.php?rid=3273334&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153691%26dopt%3DAbstract CONCLUSIONS: Using SPR on EEG recordings it is possible to separate AD from controls. This separation can be increased by the use of scopolamine but the medication is not a prerequisite for classification. The results indicate that SPR is useful for predicting progress of MCI to AD. SIGNIFICANCE: EEG registration is a simple and noninvasive method. If these results are confirmed in other studies, this method could be more widely applied than the highly specialized methods used today in detection of early AD. PMID: 20153691 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273334 Thu, 11 Feb 2010 00:00:00 +0100 3273334 http://www.medworm.com/index.php?rid=3273333&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153692%26dopt%3DAbstract CONCLUSIONS: In contrast to electrical stimulation, both ES1 and ES2 appeared and saturated with painless magnetic stimuli. SIGNIFICANCE: The present results indicate that both ES1 and ES2 have a non-nociceptive origin. Painless magnetic stimuli will be an advantage in ES reflex examinations for various orofacial pain conditions. PMID: 20153692 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273333 Thu, 11 Feb 2010 00:00:00 +0100 3273333 http://www.medworm.com/index.php?rid=3273344&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153246%26dopt%3DAbstract CONCLUSIONS: The spinal, presumed group II, excitation from ankle dorsiflexors to knee extensors is particularly enhanced during post-stroke walking probably due to plastic adaptations in the descending control. SIGNIFICANCE: This adaptation may help to stabilize the knee in early stance when the patients have recover ankle dorsiflexor functions. PMID: 20153246 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273344 Wed, 10 Feb 2010 00:00:00 +0100 3273344 http://www.medworm.com/index.php?rid=3273343&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153247%26dopt%3DAbstract CONCLUSIONS: Anisotropy of muscle conductivity increases markedly after subacute denervation injury. SIGNIFICANCE: This alteration in anisotropy has direct relevance to the clinical application of electrical impedance myography. We also speculate that it may impact other forms of diagnostic testing, including needle electromyography and magnetic resonance imaging. PMID: 20153247 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273343 Wed, 10 Feb 2010 00:00:00 +0100 3273343 http://www.medworm.com/index.php?rid=3273342&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153248%26dopt%3DAbstract CONCLUSION: Anodal and cathodal tsDCS is a non-invasive and painless method that is able to induce lasting changes in the efficacy of the Ia fibre-motoneurone synapse. SIGNIFICANCE: Transcutaneous spinal DC stimulation might be a valuable new tool in modulating spinal motor pathways. PMID: 20153248 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273342 Wed, 10 Feb 2010 00:00:00 +0100 3273342 http://www.medworm.com/index.php?rid=3273341&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153249%26dopt%3DAbstract CONCLUSIONS: A dominant as well as a consistent interictal focus is concordant with the ictal onset zone in the majority of TSC patients. SIGNIFICANCE: Future studies of TSC patients addressing the value of interictal foci in the consideration of epilepsy surgery, in absence of clear ictal onset zone, are necessary. PMID: 20153249 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273341 Wed, 10 Feb 2010 00:00:00 +0100 3273341 http://www.medworm.com/index.php?rid=3273340&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20153250%26dopt%3DAbstract Authors: Sidhoumi D, Braha S, Bouaziz N, Brunelin J, Benadhira R, Januel D PMID: 20153250 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273340 Wed, 10 Feb 2010 00:00:00 +0100 3273340 http://www.medworm.com/index.php?rid=3273345&cid=s_38452_25_f&fid=35404&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20149725%26dopt%3DAbstract CONCLUSION: High-frequency TENS to the forearm muscle modulates excitability of the limited area of motor cortex but wider area of primary somatosensory cortex. SIGNIFICANCE: High-frequency TENS to the forearm muscle modulates excitability of the primary somatosensory cortex and motor cortex in a different manner. PMID: 20149725 [PubMed - as supplied by publisher] (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3273345 Tue, 09 Feb 2010 00:00:00 +0100 3273345 http://www.medworm.com/index.php?rid=3243518&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007755%2Fabstract%3Frss%3Dyes Rhythmic oscillatory activity within the theta frequency band (4–8Hz in humans; 4–12Hz in rodents) has long attracted attention, as it has been implicated in diverse brain functions. After Klimesch and colleagues reported experimental evidence showing that episodic memory processes are associated with activity within the theta band (), the existence of an association between theta rhythm and episodic memory in humans () and rodents () has become widely accepted. Episodic memory impairment is one of the most prevalent cognitive impairments in patients with Alzheimer’s disease (AD) (), and a subtle decline in episodic memory often occurs prior to the emergence of the full dementia syndrome in nondemented older adults who develop Alzheimer’s disease (). This pattern of episodic memory... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243518 Fri, 05 Feb 2010 17:07:57 +0100 3243518 http://www.medworm.com/index.php?rid=3243517&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006713%2Fabstract%3Frss%3Dyes Dystonia is a movement disorder characterized by sustained, repetitive muscle contractions of opposing muscles accompanied by twisting and abnormal posture. Recently, deep brain stimulation (DBS) of the Globus Pallidus internus (GPi) has been shown to be an effective treatment in reducing symptoms of primary dystonia () in children and adults () as well as in generalized, focal or segmental dystonia (). (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243517 Fri, 05 Feb 2010 17:07:57 +0100 3243517 http://www.medworm.com/index.php?rid=3243516&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007494%2Fabstract%3Frss%3Dyes Conclusions: These findings provide evidence that time of day does not significantly influence corticospinal and intracortical excitability in the primary motor cortex.Significance: These results provide no support for the hypothesis that synapses within the motor cortex undergo potentiation due to daytime use and behavioural experiences. Additionally, these findings provide evidence that measurement of motor cortical excitability is not systematically biased by time-of-day dependent variability and thus does not pose a confound in studies assessing corticospinal excitability longitudinally. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243516 Fri, 05 Feb 2010 17:07:57 +0100 3243516 http://www.medworm.com/index.php?rid=3243515&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007767%2Fabstract%3Frss%3Dyes Abstract: Objective: Ageing is accompanied by diminished practice-dependent plasticity. We investigated the effect of age on another plasticity inducing paradigm, repetitive transcranial magnetic stimulation (rTMS).Methods: Healthy young (n=15; 25±4years) and old (n=15; 67±5years) adults participated in two experiments. Motor evoked potentials (MEPs) were measured in the target muscle (first dorsal interosseus, FDI) and a remote muscle (abductor digiti minimi) during a set of single stimuli. Subjects then received real or sham inhibitory rTMS (intermittent subthreshold trains of 6Hz stimulation for 10min). MEPs were measured for 30min after rTMS.Results: In young adults, MEPs in the target FDI muscle were ∼15% smaller in the real rTMS experiment than in the sham rTMS experiment (P (Sou... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243515 Fri, 05 Feb 2010 17:07:57 +0100 3243515 http://www.medworm.com/index.php?rid=3243514&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007408%2Fabstract%3Frss%3Dyes Conclusions: Cerebrocortical activity becomes altered prior to arm movements requiring APAs for individuals with chronic LBP.Significance: These results support a theoretical model that altered central motor neurophysiology associates with LBP, thereby implying that rehabilitation strategies should address these neuromotor impairments. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243514 Fri, 05 Feb 2010 17:07:57 +0100 3243514 http://www.medworm.com/index.php?rid=3243513&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006804%2Fabstract%3Frss%3Dyes Conclusions: Breaks during conventional high-frequency rTMS are a crucial factor determining the direction of induced neuroplastic changes.Significance: These results contribute to the understanding of rTMS-induced neuroplasticity and are important for the design of rTMS protocols both for experimental and clinical studies. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243513 Fri, 05 Feb 2010 17:07:56 +0100 3243513 http://www.medworm.com/index.php?rid=3243512&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006762%2Fabstract%3Frss%3Dyes Conclusions: Movement observation is accompanied by changes in the beta oscillatory activity of the STN, similar to those observed in the EEG.Significance: These changes suggest that the basal ganglia might be engaged by the activity of the human mirror system. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243512 Fri, 05 Feb 2010 17:07:56 +0100 3243512 http://www.medworm.com/index.php?rid=3243511&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006737%2Fabstract%3Frss%3Dyes Conclusions: We contend that the anterior intraparietal area and the dorsal premotor cortex are both involved albeit at different phases during the mapping of arbitrary visual cues with goal directed grasp and transport movements.Significance: These data add to the current understanding of how human cortical areas work in concert during manual activities. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243511 Fri, 05 Feb 2010 17:07:56 +0100 3243511 http://www.medworm.com/index.php?rid=3243510&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006725%2Fabstract%3Frss%3Dyes Conclusions: Biomechanical properties of the object do not seem to be used by the CNS as a first line information to evaluate GF when handling an object or transferring information about the grasp to the opposite hemisphere.Significance: The predictive scaling of GF rather reflects an internal sense of effort than an internal representation of the mechanical object properties. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243510 Fri, 05 Feb 2010 17:07:56 +0100 3243510 http://www.medworm.com/index.php?rid=3243509&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006671%2Fabstract%3Frss%3Dyes Conclusions: Our method is a viable model-free measure of temporally varying causal interactions that is capable of distinguishing linear and nonlinear information flow. With respect to experimental application, there are both linear and nonlinear information flows in CM interaction from contralateral sensorimotor cortex to muscle, which may reflect the motor command from brain to muscle.Significance: This is the first study to show separate linear and nonlinear information flow in CM interaction. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243509 Fri, 05 Feb 2010 17:07:56 +0100 3243509 http://www.medworm.com/index.php?rid=3243508&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007573%2Fabstract%3Frss%3Dyes Conclusions: The difference in P1 amplitude between two conditions can be explained by the difference between conditions, one of which yielded depth perception while the other did not, since previous studies showed that P1 and N1 are modulated by perception of images in depth. The role of P2 and the mechanism responsible for the increase in P2 amplitude during condition II remain unknown.Significance: We recorded VEPs and identified electrophysiological correlates of depth perception with 3D images produced by concave/convex figures. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243508 Fri, 05 Feb 2010 17:07:56 +0100 3243508 http://www.medworm.com/index.php?rid=3243507&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709006658%2Fabstract%3Frss%3Dyes Abstract: Objective: To determine the impact of the regional retinal responses on cortical visually evoked responses, by evaluating the relationship between multifocal ERG (mfERG) and multifocal VEP (mfVEP), in the retinitis pigmentosa (RP) model.Methods: MfERGs and mfVEPs were recorded from 20 typical RP patients. Response amplitude density (RAD, nV/deg2) and implicit time (ms) of the mfERG 1st order binary kernel (N1-P1) and mfVEP 2nd order binary kernel (P1) components were measured. Ring analysis, matched for mfERG and mfVEP stimuli, was performed between fovea and mid-periphery (0–2.5, 2.5–5, 5–10, 10–15 and 15–20deg).Results: At central and pericentral retinal regions (four eccentricities between 0 and 15deg), mfERG N1 RADs were positively correlated (r⩾0.68, p (Source: C... Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243507 Fri, 05 Feb 2010 17:07:56 +0100 3243507 http://www.medworm.com/index.php?rid=3243506&cid=s_38452_168_f&fid=38452&url=http%3A%2F%2Fwww.clinph-journal.com%2Farticle%2FPIIS1388245709007548%2Fabstract%3Frss%3Dyes Conclusions: Although double pulses are more efficient compared to single pulses the advantage is rather small. Previous recommendations to apply double pulses in phosphene studies cannot be confirmed, at least for SOAs up to 20ms. The independence of fusion time to stimulus intensity indicates a non-linear relation between network activity and the percept of phosphene persistence.Significance: Phosphene threshold studies do not gain advantages by the application of double pulses. (Source: Clinical Neurophysiology) Clinical Neurophysiology journals http://www.medworm.com/rss/comments.php?id=3243506 Fri, 05 Feb 2010 17:07:56 +0100 3243506