MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Clinical Nutrition' source. Wed, 08 Feb 2012 22:31:35 +0100 http://www.medworm.com/index.php?rid=5630786&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561412000143%2Fabstract%3Frss%3Dyes (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630786 Fri, 27 Jan 2012 03:31:19 +0100 5630786 http://www.medworm.com/index.php?rid=5630785&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141200009X%2Fabstract%3Frss%3Dyes (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630785 Fri, 27 Jan 2012 03:31:19 +0100 5630785 http://www.medworm.com/index.php?rid=5630812&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411002147%2Fabstract%3Frss%3Dyes We thank Dr. Klevay’s for her reflection on the potential role that copper may play in explaining an inverse association between chocolate consumption and prevalent coronary artery disease (CAD) in the National Heart, Lung, and Blood Institute Family Heart Study. Unfortunately, we were not able to explore possible mediation of the chocolate-CAD relation by copper concentration, mainly due to the cross-sectional design of our study and the lack of data on individual food contribution to total copper. For example, having data on the proportion of total copper provided by chocolate would have allowed us to see if its adjustment led to an attenuation of the odds ratio for CAD. There is a need to further evaluate individual nutrients in chocolate/cocoa (i.e., flavonoids, potassium, magnesium,... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630812 Wed, 23 Nov 2011 05:00:00 +0100 5630812 http://www.medworm.com/index.php?rid=5630811&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411002159%2Fabstract%3Frss%3Dyes Djousse et al., described an inverse epidemiologic association between chocolate consumption and coronary heart disease prevalence. They suggested that dark chocolate contains potentially beneficial ingredients such as flavonoids, potassium and magnesium. Chocolate also is high in copper, an antioxidant nutrient for cardiovascular health. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630811 Thu, 17 Nov 2011 05:00:00 +0100 5630811 http://www.medworm.com/index.php?rid=5630805&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001750%2Fabstract%3Frss%3Dyes Conclusions: Malnutrition as diagnosed with the MNA at admission failed to predict long-term mortality in older inpatients, likely due to the overriding impact of co-morbidities and acute disease. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630805 Wed, 28 Sep 2011 04:00:00 +0100 5630805 http://www.medworm.com/index.php?rid=5630790&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001749%2Fabstract%3Frss%3Dyes Conclusion: CVAD complications, in particular line infection are still a major source of potentially avoidable HPN morbidity and mortality with a high cost to the healthcare system. The predominance of enteric organisms in our series raises the possibility of bacterial translocation as a significant component of the pathogenesis of line sepsis in HPN patients. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630790 Mon, 26 Sep 2011 04:00:00 +0100 5630790 http://www.medworm.com/index.php?rid=5630806&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001725%2Fabstract%3Frss%3Dyes Summary: Background & aims: Impaired growth and nutritional status in CF may be related to progressive insulin deficiency before CF-Related Diabetes has established. Aim of this study was to analyse the association of circulating insulin with nutritional status and lung function in CF patients with normal glucose tolerance (NGT).Methods: We performed OGTT in 152 consecutive CF patients aged 8–20 years: 115 of them had NGT and were included in the study. Areas under the curves (AUC) of glucose, insulin and c-peptide after 120 min were calculated. Quartiles (Q) of increasing fasting insulin (fINS-Q) and c-peptide (fCP-Q) levels were calculated in CF patients. Respiratory function parameters (FEV1, FVC), Standard Deviation Scores (SDS) of height, weight and BMI were compared between Q1 and... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630806 Fri, 23 Sep 2011 04:00:00 +0100 5630806 http://www.medworm.com/index.php?rid=5630813&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001580%2Fabstract%3Frss%3Dyes The recent article by Kwok et al. has contributed to the mounting evidence that has failed to find a link between homocysteine reduction and cognition. This frustrating absence of positive results is not entirely unsurprising, however. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630813 Mon, 19 Sep 2011 04:00:00 +0100 5630813 http://www.medworm.com/index.php?rid=5630803&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001592%2Fabstract%3Frss%3Dyes Summary: Background & aims: One of the most prevalent complications of pregnancy is asthma which is associated with an increased incidence of intrauterine growth restriction. The mechanisms that affect fetal development in pregnancies complicated by asthma are not clearly defined. Antioxidants are particularly important during pregnancy due to their protective role against a state of high oxidative stress as gestation progresses. The current study was designed to characterise the circulating profile of tocopherols and carotenoids in pregnant women with asthma to determine whether asthma severity and dietary intake were associated with an altered antioxidant profile.Methods: Maternal dietary intake and plasma and erythrocyte concentrations of tocopherols and carotenoids were examined in wom... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630803 Mon, 19 Sep 2011 04:00:00 +0100 5630803 http://www.medworm.com/index.php?rid=5630793&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001555%2Fabstract%3Frss%3Dyes Conclusion: There was no difference in the durability and the complication between Groshong Catheter and PI Catheter. (UMIN Clinical Trial Registry UMIN000005451). (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630793 Mon, 19 Sep 2011 04:00:00 +0100 5630793 http://www.medworm.com/index.php?rid=5630787&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001579%2Fabstract%3Frss%3Dyes Conclusion: There is insufficient evidence to recommend routine probiotics. However, there is encouraging data (2b LoE) which justifies the further investigation regarding the efficacy and safety of specific probiotics in circumstances of high local incidence of severe NEC. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630787 Mon, 19 Sep 2011 04:00:00 +0100 5630787 http://www.medworm.com/index.php?rid=5630795&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001567%2Fabstract%3Frss%3Dyes Conclusion: These data support previous findings of increased colonocyte DNA damage with greater red and white meat intake and also the protective effect of dietary fibre. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630795 Thu, 15 Sep 2011 04:00:00 +0100 5630795 http://www.medworm.com/index.php?rid=5630788&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001543%2Fabstract%3Frss%3Dyes Summary: Patients with phenylketonuria (PKU) must follow a strict low-phenylalanine (Phe) diet in order to minimise the potentially disabling neuropsychological sequelae of the disorder. Research in this area has unsurprisingly focussed largely on managing blood Phe concentrations to protect the brain. Protein requirements in dietary management of PKU are met mostly from Phe-free protein substitutes with the intake of natural protein restricted to patient tolerance. Several reports have suggested that growth in early childhood in PKU is sub-optimal, relative to non-PKU control groups or reference populations. We reviewed the literature searching for evidence regarding PKU and growth as well as possible links between dietary management of PKU and growth. The search retrieved only limited ev... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630788 Thu, 15 Sep 2011 04:00:00 +0100 5630788 http://www.medworm.com/index.php?rid=5630799&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001531%2Fabstract%3Frss%3Dyes Conclusion: Hydration status was not affected by salt intake in this sample of healthy children and adolescents in a western life style, due to a compensatory increase in beverage consumption. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630799 Wed, 07 Sep 2011 04:00:00 +0100 5630799 http://www.medworm.com/index.php?rid=5443331&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141100152X%2Fabstract%3Frss%3Dyes Conclusion: This meta-analysis is consistent with a lack of n-3 PUFA effects on IS. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443331 Wed, 07 Sep 2011 04:00:00 +0100 5443331 http://www.medworm.com/index.php?rid=5630789&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001518%2Fabstract%3Frss%3Dyes Conclusion: The results indicate that probiotics lower the genotoxic potential of faecal water in AD patients. The faecal C. perfringens cluster I–II levels remained unaffected suggesting either a change in their activity, or the fact that other bacterial species are responsible for the reduced genotoxic activity of faecal water. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630789 Thu, 01 Sep 2011 04:00:00 +0100 5630789 http://www.medworm.com/index.php?rid=5630794&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141100149X%2Fabstract%3Frss%3Dyes We describe an observational study in critically ill medical patients showing the association between serum Vitamin B12 levels measured on or near admission and the outcome in these patients.Methods: We used the database of patients admitted to the Medical Intensive Care Unit (MICU) at the Hadassah-Hebrew University Medical Center in Jerusalem, Israel, to analyze associations between patient demographics, background, diagnoses and serum Vitamin B12 levels with hospital and 90 day outcomes.Results: Higher mean Vitamin B12 levels were found in patients who did not survive their hospital stay (1719 pg/ml vs 1003 pg/ml, p  (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630794 Mon, 29 Aug 2011 04:00:00 +0100 5630794 http://www.medworm.com/index.php?rid=5630791&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001506%2Fabstract%3Frss%3Dyes Conclusions: One quarter of these hospitalized children were overweight or obese. NRSs identified a group of children at increased risk of nutritional deterioration who subsequently had longer hospital stays. Use of NRSs at admission can identify children requiring focused nutritional assessment. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630791 Mon, 29 Aug 2011 04:00:00 +0100 5630791 http://www.medworm.com/index.php?rid=5630798&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001476%2Fabstract%3Frss%3Dyes Summary: Background & aims: Patients with sarcopenia [reduced fat free mass (FFM)] have a higher incidence of chemotherapy-related toxicity and decreased survival. As there are no such data in patients with oesophagogastric cancer (OGC), this study investigated changes in body composition in OGC patients receiving neoadjuvant chemotherapy (NAC).Methods: OGC patients who had CT scans before and after NAC were studied. CT images at the L3 vertebral level were analysed using SliceOmatic® software to derive estimates of FFM and fat mass (FM). Comparisons were made between pre- and post-NAC CT images. Data are reported as mean ± SD.Results: Forty-seven patients (34 male) aged 63 ± 12 years were studied and 79% completed their course of NAC. The interval between CT scans was 107 ± 27 d... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630798 Mon, 22 Aug 2011 04:00:00 +0100 5630798 http://www.medworm.com/index.php?rid=5630797&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001464%2Fabstract%3Frss%3Dyes Summary: Background & aims: Elderly subjects are at risk for undernutrition. Restrictive diets may increase this risk. The aim was to evaluate the impact of restrictive diets on undernutrition and its risk in free-living elderly.Methods: Ambulatory patients over age 75 and under a restrictive diet (low salt, low cholesterol, diabetic) were included prospectively, along with age- and gender-matched controls. Weight and height were measured, and the short-form of the Mini Nutritional Assessment was scored. Groups were compared to determine variables associated with a low MNA-SF®.Results: 95 patients in the diet group (62 F, 33 M, 80 ± 4 y) and 95 controls (57 F, 38 M, 82 ± 5 y) were included. Restrictive diets (low salt n = 33, diabetic n = 19, low cholesterol n = 15, comb... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630797 Mon, 22 Aug 2011 04:00:00 +0100 5630797 http://www.medworm.com/index.php?rid=5630796&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001488%2Fabstract%3Frss%3Dyes Conclusions: The extra costs related to malnutrition are a considerable burden for the nursing home sector and urge for preventive measures. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630796 Mon, 22 Aug 2011 04:00:00 +0100 5630796 http://www.medworm.com/index.php?rid=5630810&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001452%2Fabstract%3Frss%3Dyes Conclusions: Our results confirm the importance of defining reference values of total body impedance vector for each country in view of the considerable ethnic diversity among different geographical areas. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630810 Tue, 16 Aug 2011 04:00:00 +0100 5630810 http://www.medworm.com/index.php?rid=5630809&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001427%2Fabstract%3Frss%3Dyes Conclusions: The majority of children exposed to an initially disliked bar increase acceptance after nine exposures to the same level as an initially liked bar. Children repeatedly exposed to a liked bar show stable acceptance. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630809 Thu, 11 Aug 2011 04:00:00 +0100 5630809 http://www.medworm.com/index.php?rid=5630802&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001440%2Fabstract%3Frss%3Dyes Conclusion: Our results suggest that intake of antioxidant vitamins might modify the association between genetic polymorphisms of NOS3 and breast cancer risk. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630802 Thu, 11 Aug 2011 04:00:00 +0100 5630802 http://www.medworm.com/index.php?rid=5443330&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001439%2Fabstract%3Frss%3Dyes This report summarizes updated key conclusions of the workshop with regards to micronutrients’ intake and physiological role related to mother, placenta and fetus, as well as relevance for adverse pregnancy and long-term outcomes. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443330 Thu, 11 Aug 2011 04:00:00 +0100 5443330 http://www.medworm.com/index.php?rid=5630801&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001403%2Fabstract%3Frss%3Dyes We examined the association between breakfast cereal consumption and the risk of hypertension.Methods: We prospectively analyzed data from 13,368 male participants of the Physicians’ Health Study I. Consumption of breakfast cereals was estimated using an abbreviated food frequency questionnaire and incident hypertension was ascertained through yearly follow-up questionnaires.Results: The average age of study participants was 52.4 ± 8.9 years (range 39.7–85.9) during the initial assessment of cereal intake (1981–1983). During a mean follow up of 16.3 years, 7267 cases of hypertension occurred. The crude incidence rates of hypertension were 36.7, 34.0, 31.7, and 29.6 cases/1000 person-years for people reporting breakfast cereal intake of 0, ≤1, 2–6, and ≥7 servings/week, respe... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630801 Mon, 08 Aug 2011 04:00:00 +0100 5630801 http://www.medworm.com/index.php?rid=5630792&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001415%2Fabstract%3Frss%3Dyes Summary: Background & aims: One aim of the Australasian Nutrition Care Day Survey was to determine the nutritional status and dietary intake of acute care hospital patients.Methods: Dietitians from 56 hospitals in Australia and New Zealand completed a 24-h survey of nutritional status and dietary intake of adult hospitalised patients. Nutritional risk was evaluated using the Malnutrition Screening Tool. Participants ‘at risk’ underwent nutritional assessment using Subjective Global Assessment. Based on the International Classification of Diseases (Australian modification), participants were also deemed malnourished if their body mass index was (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630792 Mon, 08 Aug 2011 04:00:00 +0100 5630792 http://www.medworm.com/index.php?rid=5630800&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001397%2Fabstract%3Frss%3Dyes Conclusion: IL-6 may not best represent the clinical correlates of CC in ACP. Additional cytokines should be considered in the definition of this condition. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630800 Mon, 01 Aug 2011 04:00:00 +0100 5630800 http://www.medworm.com/index.php?rid=5072210&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001257%2Fabstract%3Frss%3Dyes Unfortunately, when this article was originally published there was a spelling error in the title; the correct title is printed above. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072210 Fri, 29 Jul 2011 16:09:17 +0100 5072210 http://www.medworm.com/index.php?rid=5630808&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001373%2Fabstract%3Frss%3Dyes Summary: Background & aims: There is growing awareness that vitamin D sufficiency is required for overall optimal health. Most experts agree that 25-hydroxyvitamin D levels of at least 75 nmol/L, as sufficient vitamin D status. Our aim was to investigate the serum 25-hydroxyvitamin D concentration required in mid-October to ensure vitamin D sufficiency in early February, and to assess the rate of vitamin D insufficiency in both seasons.Methods: We measured serum 25-hydroxyvitamin D, parathormone, and other related biochemical parameters, in a sample of 28 professional football players homogeneous in factors influencing serum 25-hydroxyvitamin D concentration in a sunny area of southern Spain.Results: The serum 25-hydroxyvitamin D concentration of 122.7 nmol/L was required; 14.3% reached ... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630808 Thu, 28 Jul 2011 04:00:00 +0100 5630808 http://www.medworm.com/index.php?rid=5630804&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001385%2Fabstract%3Frss%3Dyes This study aimed to evaluate influence of protein composition on rate of gastric emptying and study the relation between gastric emptying and postprandial gastrointestinal symptoms.Methods: 15 children with cerebral palsy, using gastrostomy, received four liquid test meals on separate days in random order. The meals contained a standard carbohydrate and fat base plus one of four protein modules (100% casein (A), hydrolysed whey (B), amino acids (C) and 40% casein/60% whey (D)) with a total energy of 1 kcal/ml. The 13C octanoic acid breath test was applied to assess gastric emptying.Results: When comparing half emptying time (T1/2) of the fast emptying meals (meal B, C and D) with the slowest emptying meal (meal A), more rapid emptying was demonstrated for meal D (p  (Source: Clinical Nut... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630804 Thu, 28 Jul 2011 04:00:00 +0100 5630804 http://www.medworm.com/index.php?rid=5443332&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001361%2Fabstract%3Frss%3Dyes Conclusions: Results demonstrated that postoperative nutritional intervention generates comparable results regardless of the route and formula used and that preoperative intervention is of the utmost importance.The study was registered in the Clinical Trials Database – number: NCT 00558155. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443332 Mon, 25 Jul 2011 04:00:00 +0100 5443332 http://www.medworm.com/index.php?rid=5306273&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001336%2Fabstract%3Frss%3Dyes “Medical nutrition” is a novel concept born with the recognition of the importance of malnutrition as a consequence, complication and cause of perpetuation and aggravation of several illnesses. Recent advances and progresses in the non-nutritional management and treatment of different disease states associated with malnutrition highlighted the need for a truly scientific appraisal of nutrition therapy. Indeed, several outcome variables worsened in case of concomitant malnutrition, even when the underlying disease was managed according to the best standards of non-nutritional care. An appropriate nutritional therapy is likely able to improve outcome via the correction or prevention of malnutrition-related complications. However, the lack of standardization for the prescription of nutrit... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306273 Wed, 20 Jul 2011 04:00:00 +0100 5306273 http://www.medworm.com/index.php?rid=5443354&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001130%2Fabstract%3Frss%3Dyes Conclusions: TRF has anti-fibrogenic effects on HIF, decreasing ECM production and increasing its degradation. This effect is mediated, at least in part, by inhibition of TGF-β1. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443354 Mon, 18 Jul 2011 04:00:00 +0100 5443354 http://www.medworm.com/index.php?rid=5443335&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001026%2Fabstract%3Frss%3Dyes The objective of this study was to develop a nutrition screening tool that could be used to identify cancer patients at risk for malnutrition.Methods: Of 3010 cancer patients admitted to the National Cancer Center of Korea between April 1 and June 2, 2008, the nutritional status of 1057 patients was assessed by the Scored Patient-Generated Subjective Global Assessment (PG-SGA). Variables used in current nutrition screening tools were analyzed to select indices for a developing malnutrition screening tool for cancer patients (MSTC). The equation for the MSTC was established using receiver operating characteristics curves. Sensitivities and specificities of the MSTC were calculated using the PG-SGA as gold standard.Results: The MSTC was calculated as follows: [MSTC = −0.116 + (1.777 �... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443335 Mon, 18 Jul 2011 04:00:00 +0100 5443335 http://www.medworm.com/index.php?rid=5630807&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001312%2Fabstract%3Frss%3Dyes Summary: Background & aims: The growth of very low birth weight infants does not match intrauterine trajectories, likely due to inappropriate caloric intake. We therefore investigated whether modification of the standard nutritional schedule can impact postnatal growth.Methods: We introduced a set of evidence-based strategies in a study group of infants (n = 123): 1) higher maximum intake of intravenous amino acids and lipids; 2) prioritisation of earlier enteral feeding; 3) faster attainment of full enteral feeds; 4) daily adjustment of enteral feeds according to growth trajectory; and 5) utilisation of an electronic pre-structured prescription ordering system that tracks individual growth and energy intake. These infants were compared with a control group (n = 115) in a pre/post ret... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5630807 Fri, 15 Jul 2011 04:00:00 +0100 5630807 http://www.medworm.com/index.php?rid=5443339&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001324%2Fabstract%3Frss%3Dyes Summary: Background & aims: Many studies have suggested that obese patients with chronic heart failure have a better prognosis than leaner patients. The main purpose of this study was to assess the prognostic value of body mass index in patients with chronic heart failure, independently of other poor prognosis parameters.Methods: This retrospective study included 405 heart failure patients. Anthropometric, body composition, clinical, biochemical, and echocardiographic data were collected from all patients. Patients were classified as: underweight ( (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443339 Fri, 15 Jul 2011 04:00:00 +0100 5443339 http://www.medworm.com/index.php?rid=5443337&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001300%2Fabstract%3Frss%3Dyes Conclusions: The addition of serum albumin marker may not have much advantage to predict pressure ulcer healing although its level can be associated with ulcer healing, depending on patient condition and wound depth. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443337 Fri, 15 Jul 2011 04:00:00 +0100 5443337 http://www.medworm.com/index.php?rid=5443333&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001129%2Fabstract%3Frss%3Dyes Summary: The use of nutritional support in cancer patients has evolved since its introduction in the clinical practice 40 years ago. Both parenteral and enteral nutrition are now increasingly integrated within the main oncologic strategy with the aim of making surgery, chemotherapy and radiation therapy more safe and effective. This requires a better awareness of the inherent risk of starvation and undernutrition by the surgeons, medical oncologists and radiologists, the ability to implement a policy of nutritional screening of cancer patients and to propose them the nutritional support in a single bundle together with the oncologic drugs. Four different areas of nutritional intervention are now recognized which parallel the evolutionary trajectory of patients with tumour: the perioperativ... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443333 Mon, 11 Jul 2011 04:00:00 +0100 5443333 http://www.medworm.com/index.php?rid=5443349&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001117%2Fabstract%3Frss%3Dyes Conclusions: Loss of lean mass over a period of six months after a first assessment is associated with worse prognosis in alcoholics, irrespective of whether they stop drinking during this period or not. Continued drinking is associated with greater loss of lean mass, but not with changes in fat mass. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443349 Fri, 08 Jul 2011 04:00:00 +0100 5443349 http://www.medworm.com/index.php?rid=5443341&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001099%2Fabstract%3Frss%3Dyes Summary: Background & aims: Progress in management of cerebral palsy (CP) patients has helped to increase life expectancy, but has also revealed nutritional consequences of this disability. The aims of this study were to determine the prevalence of malnutrition in long-term-institutionalized adult patients with CP and to propose specific malnutrition screening tool.Methods: Practitioners at 15 specialized institutions hosting CP patients assessed their nutritional status and completed a binary questionnaire containing thirteen questions related to factors suspected of increasing malnutrition. Moderate malnutrition was defined as the following: loss of weight (%) ≥5 to (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443341 Mon, 04 Jul 2011 04:00:00 +0100 5443341 http://www.medworm.com/index.php?rid=5443334&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001105%2Fabstract%3Frss%3Dyes Conclusions: A history of WCy appears related to body weight excess and abdominal fat accumulation. These findings support the importance of designing adequate weight loss programs to achieve long-term weight maintenance and to prevent undesirable and unhealthy weight accumulation. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443334 Mon, 04 Jul 2011 04:00:00 +0100 5443334 http://www.medworm.com/index.php?rid=5443351&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001087%2Fabstract%3Frss%3Dyes This study aimed to extend observations surrounding fatty acid taste, specifically the types of foods consumed and dietary behaviours that may be associated with fatty acid taste sensitivity.Methods: 51 subjects (41 female; BMI, 21.4 ± 0.46 kg/m2, age, 20 ± 0.52 yrs, 10 male; BMI, 23.6 ± 1.4 kg/m2, age, 22 ± 1 yrs) were screened for oral sensitivity to oleic acid (3.8 mM) using triplicate sensory evaluations, and classified as hypersensitive; (3/3 correct identifications), or hyposensitive, ( (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443351 Mon, 27 Jun 2011 04:00:00 +0100 5443351 http://www.medworm.com/index.php?rid=5443350&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001075%2Fabstract%3Frss%3Dyes Conclusions: Protein malabsorption was mostly undetectable using standard fecal tests. The study of the postprandial fate of dietary protein revealed a moderate increase of its transfer to metabolic pools after enzyme substitution. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443350 Wed, 22 Jun 2011 04:00:00 +0100 5443350 http://www.medworm.com/index.php?rid=5443347&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001063%2Fabstract%3Frss%3Dyes Conclusion: In healthy, well nourished volunteers, oral citrulline increases plasma citrulline and arginine availability but does not affect whole-body protein kinetics in the post-absorptive state. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443347 Wed, 22 Jun 2011 04:00:00 +0100 5443347 http://www.medworm.com/index.php?rid=5306276&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141100104X%2Fabstract%3Frss%3Dyes Conclusion: Results of this small pilot study in rectal cancer patients receiving preoperative radiochemotherapy, showed that ingestion of larger quantities of glutamine given more often as previously reported did not diminish the incidence and severity of diarrhoea and did not affect inflammatory and metabolic activity compared to the placebo treatment with maltodextrin.Highlights: ► Glutamine ingestion was studied in rectal cancer patients during preoperative radiochemotherapy. ► Patients received 30 g of glutamine for five weeks. ► We found glutamine in this dose does not diminish the incidence and severity of diarrhoea. ► We also found no influence on inflammatory and metabolic response. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306276 Wed, 22 Jun 2011 04:00:00 +0100 5306276 http://www.medworm.com/index.php?rid=5306274&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001051%2Fabstract%3Frss%3Dyes This article aims at reviewing present knowledge on these topics in order to determine energy requirements for maintaining a neutral energy balance in ALS patients. Maintaining a neutral energy balance prevents malnutrition and its complications and may improve physical functioning, quality of life and survival.Prevalence of malnutrition varies between 16 and 55% in ALS patients. Energy intakes are below recommended dietary allowances in 70% of ALS patients at least. These elements suggest a chronic negative energy balance with an imbalance between requirements and intakes. While insufficient intakes can be compensated with nutritional support, the energy requirements are unclear. Studies generally report hypermetabolism in ALS patients. Estimation of total energy expenditure and as a coro... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306274 Fri, 17 Jun 2011 04:00:00 +0100 5306274 http://www.medworm.com/index.php?rid=5443338&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001014%2Fabstract%3Frss%3Dyes Conclusion: The best available BIA equation to calculate the FFM and the FM in patients with AN is the Deurenberg equation. It takes into account the weight, height and age and is applicable in adults and adolescents AN patients with BMI of 12.8–21.0, and for ages between 13.4 and up to 36.9 years. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443338 Thu, 16 Jun 2011 04:00:00 +0100 5443338 http://www.medworm.com/index.php?rid=5072187&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001038%2Fabstract%3Frss%3Dyes During the last 3 decades, our society has become one of the leading nutrition societies in the world. The reason of this ongoing success is the mix of outstanding health professionals giving the best of their knowledge and experience, and an international network, regardless of competition or financial interest. This comprehensive structure cannot be beaten since the best experts are working together. In addition to the friendship created around this achievement, there is a feeling of euphoria when so many countries from Chile to Australia and Japan are joining ESPEN changing the society created in 1979 into a world large respected organization. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072187 Sun, 12 Jun 2011 23:00:00 +0100 5072187 http://www.medworm.com/index.php?rid=5443344&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411001002%2Fabstract%3Frss%3Dyes Conclusions: The current recommended glucose infusion induces hyperglycemia in post-surgical children. A reduced glucose infusion safely reduced high glucose levels, while children were capable to sustain normoglycemia with increased endogenous glucose production. The reduced glucose infusion did not exacerbate the mild catabolic state in which the patients were. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443344 Fri, 03 Jun 2011 04:00:00 +0100 5443344 http://www.medworm.com/index.php?rid=5443348&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000999%2Fabstract%3Frss%3Dyes This study aimed to assess criterion-based validity of an accelerometer-based activity monitoring system (AM-system), ActivPAL™, using two different methods.Methods: Advanced cancer in patients and outpatients (Karnofsky Performance Status (KPS) 40–100). ActivPAL™ measurements were validated against (i) observations and (ii) energy expenditure (EE) measured by 2-week doubly-labelled water (DLW) protocol.Results: Absolute errors for mean time spent in different body positions ( (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443348 Thu, 02 Jun 2011 04:00:00 +0100 5443348 http://www.medworm.com/index.php?rid=5443346&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000987%2Fabstract%3Frss%3Dyes Conclusions: The age-related MPS response to anabolic signals was improved in rats fed an oleate-enriched diet. This effect was related to activation of muscle oxidative pathways, lower IR, and a decrease in inflammation. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443346 Thu, 02 Jun 2011 04:00:00 +0100 5443346 http://www.medworm.com/index.php?rid=5306295&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000756%2Fabstract%3Frss%3Dyes Summary: Background & aims: The role of endothelial cells in inflammatory bowel disease has been recently emphasized. Endothelial activation and expression of adhesion molecules are critical for leukocytes recruitment into the inflammatory wall. Compelling evidence demonstrated anti-inflammatory effects of long chain n-3 PUFA in inflammatory models. We previously showed that long chain n-3 PUFA (EPA and DHA) inhibited inflammatory response in epithelial and dendritic cells. As long chain n-3 PUFA treatment led to a decreased expression of adhesion molecules in endothelial cells from other organs, we have now investigated their effect on intestinal endothelial cells in vitro and in colitic rats.Methods: In vitro study: Primary culture of human intestinal microvascular endothelial cells (HI... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306295 Wed, 01 Jun 2011 04:00:00 +0100 5306295 http://www.medworm.com/index.php?rid=5443340&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000975%2Fabstract%3Frss%3Dyes The objective was to determine if a specially formulated medical food, high in leucine and protein, stimulates muscle protein synthesis acutely in individuals with cancer to a greater extent than a conventional medical food.Design: A randomized, controlled, double-blind, parallel-group design was used in 25 patients with radiographic evidence of cancer. Patients were studied before their cancer treatment was started or 4 weeks after their treatment was completed or halted. The fractional rate of muscle protein synthesis (FSR) was measured using the tracer incorporation technique with L-[ring-13C6]-phenylalanine. The experimental group (n = 13) received a medical food containing 40 g protein, based on casein and whey protein and enriched with 10% free leucine and other specific component... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443340 Mon, 30 May 2011 04:00:00 +0100 5443340 http://www.medworm.com/index.php?rid=5443336&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000951%2Fabstract%3Frss%3Dyes This study aims to systematically review the clinical efficacy of hypocaloric parenteral nutrition on surgical patients.Methods: Medline, SCI, Embase, Cochrane Library, Chinese Biomedicine Database (CBM) and China Knowledge Resource Integrated Database (CNKI) were searched for studies published before July 1, 2010. Randomized control trials (RCTs) that compared hypocaloric PN with standard or higher energy PN in surgical patients were identified and included. Methodological quality assessment was based on Cochrane Reviewers’ Handbook and modified Jadad’s Score Scale. Statistical software RevMan 5.0 was used for meta-analysis.Results: Five trials met all inclusion criteria and were included in the final meta-analysis. There were significant reductions in infectious complications (RR, 0... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443336 Mon, 30 May 2011 04:00:00 +0100 5443336 http://www.medworm.com/index.php?rid=5443352&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141100094X%2Fabstract%3Frss%3Dyes Conclusions: Probiotic bacteria have very different immune modulating capacities. Analysis of transcription factor mRNA is a suitable method for in vitro characterization of strains prior to clinical application. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443352 Wed, 25 May 2011 04:00:00 +0100 5443352 http://www.medworm.com/index.php?rid=5443353&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000902%2Fabstract%3Frss%3Dyes Summary: Background & aims: Postprandial lipemia is assessed using the oral fat tolerance test (OFTT), a six-hour procedure requiring hourly blood sampling. In order to simplify the test, we investigated whether a) a single postprandial triacylglycerol concentration, b) an OFTT lasting less than six hours or c) an OFTT requiring fewer blood samples, may accurately assess postprandial lipemia under various conditions.Methods: Seventy-two subjects underwent a conventional OFTT. Predictability of single-point concentrations and time-shortened tests was assessed using linear regression and re-sampling analysis. Validity of reduced-sampling tests was assessed using Pearson’s correlation coefficients and Bland-Altman analysis.Results: a) A single-point triacylglycerol concentration (3 or 4h ... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443353 Thu, 19 May 2011 04:00:00 +0100 5443353 http://www.medworm.com/index.php?rid=5306289&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000914%2Fabstract%3Frss%3Dyes Conclusions: The observed associations are in line with suggested sleep-improving effects of carbohydrates. Effect sizes suggest that the clinical relevance of nutritional composition for sleep duration is limited in healthy young toddlers. These observations and their possible importance for more vulnerable groups need to be confirmed in clinical trials. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306289 Thu, 19 May 2011 04:00:00 +0100 5306289 http://www.medworm.com/index.php?rid=5306277&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000707%2Fabstract%3Frss%3Dyes This study assessed the efficacy of supplemented essential amino acids on depressive symptoms, nutrition, muscle function, daily physical activity, and health-related quality of life (HRQoL) of institutionalized elderly patients.Methods: Forty-one patients (58.5% women; mean age 79.8 yrs) with sequelae of coronary artery disease (73%), femoral fracture (34%), were randomly assigned to receive oral essential amino acids 4 gr 2 times a day for 8 weeks or isocaloric placebo. Before randomization and 8 weeks after the protocol started, the following variables were measured: depressive symptoms (Geriatric Depression Scale, GDS), nutritional panel (Mini Nutritional Assessment, MNA; serum albumin and prealbumin levels), muscle strength (Hand Grip, HG), Activity Daily Life (ADL), Quality of Life ... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306277 Mon, 16 May 2011 04:00:00 +0100 5306277 http://www.medworm.com/index.php?rid=5306291&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000720%2Fabstract%3Frss%3Dyes Conclusion: Patients with serum folate concentrations above 8.0 ng/ml had the lowest risk of developing colorectal adenoma. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306291 Tue, 10 May 2011 04:00:00 +0100 5306291 http://www.medworm.com/index.php?rid=5306290&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000744%2Fabstract%3Frss%3Dyes This study was to examine the relationship among body mass index, viral load and liver histology in HBeAg-negative CHB.Methods: The study retrospectively investigated 136 HBeAg-negative chronic hepatitis B patients who had undergone liver biopsies in Taiwan. Factors associated with significant liver histology were analyzed. Definitions of overweight and obesity for the Asian population were body mass index≥23kg/m2 and ≥25kg/m2, respectively.Results: The prevalence of overweight, obesity, and type 2 diabetes mellitus in the 136 patients were 22.8%, 52.2%, and 12.5%, respectively. Multivariate analysis identified obesity, AST>40 U/L, HBV DNA>20,000IU/mL and platelet count80 U/L, HBV DNA>1,000,000IU/mL, and platelet count (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306290 Tue, 10 May 2011 04:00:00 +0100 5306290 http://www.medworm.com/index.php?rid=5306279&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000732%2Fabstract%3Frss%3Dyes Summary: Background & aims: Trace element deficiencies are known to occur during long-term enteral nutrition feeding. We compared the serum concentrations of trace elements between patients treated with gastrostomy and those treated with jejunostomy.Methods: Our subjects were 36 patients who underwent percutaneous endoscopic gastrostomy (PEG group) and 23 patients who underwent percutaneous endoscopic jejunostomy (PEJ group) and were maintained with enteral tube feeding for more than one year. The serum concentrations of copper, zinc, selenium, and iron were measured in the two groups. Clinical manifestations and the effectiveness of supplementation therapy against copper deficiency were also investigated.Results: From 6 months after the onset of enteral feeding, the copper concentration o... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306279 Tue, 10 May 2011 04:00:00 +0100 5306279 http://www.medworm.com/index.php?rid=5443345&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000719%2Fabstract%3Frss%3Dyes Summary: Background & aims: Several tools are available for nutritional screening. We evaluated the risk of mortality associated with the Geriatric Nutritional Risk Index (GNRI) and the Mini Nutritional Assessment (MNA) in newly institutionalised elderly.Methods: A prospective observational study involving 358 elderly newly admitted to a long-term care setting. Hazard ratios (HR) for mortality among GNRI categories and MNA classes were estimated by multivariable Cox’s model.Results: At baseline, 32.4% and 37.4% of the patients were classified as being malnourished (MNA (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443345 Mon, 09 May 2011 04:00:00 +0100 5443345 http://www.medworm.com/index.php?rid=5306282&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000689%2Fabstract%3Frss%3Dyes Conclusions: The low-volume enteral supplement containing key nutrients was well tolerated and led to a better vitamin E and selenium supply. However, it did not affect length of ICU or hospital stay. Further studies are necessary to determine which disease-specific subgroups may benefit from this supplementation or which group may be harmed. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306282 Fri, 06 May 2011 04:00:00 +0100 5306282 http://www.medworm.com/index.php?rid=5306281&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000690%2Fabstract%3Frss%3Dyes This study investigated associations between depression scores and participation in a community-based weight management intervention trial.Methods: A group of 64 overweight (BMI > 27), otherwise healthy adults, were recruited and randomised to follow either their usual diet, or an isocaloric diet in which saturated fat was replaced with monounsaturated fat (MUFA), to a target of 50% total fat, by adding macadamia nuts to the diet. Subjects were assessed for depressive symptoms at baseline and at ten weeks using the Beck Depression Inventory (BDI-II). Both control and intervention groups received advice on National Guidelines for Physical Activity and adhered to the same protocol for food diary completion and trial consultations. Anthropometric and clinical measurements (cholesterol, infl... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306281 Tue, 03 May 2011 04:00:00 +0100 5306281 http://www.medworm.com/index.php?rid=5306294&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000677%2Fabstract%3Frss%3Dyes Conclusions: These results showed that an early nutritional intervention with alanyl-glutamine specifically abolished the up-regulation of TLR4 expression in NMD. Glutamine may be evaluated as a potential treatment for IBS patients. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306294 Mon, 25 Apr 2011 04:00:00 +0100 5306294 http://www.medworm.com/index.php?rid=5306284&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000665%2Fabstract%3Frss%3Dyes Conclusions: DSM-BIA is a valid tool for the assessments of total body and segmental body composition in the general middle-aged population, particularly for the quantification of body lean mass. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306284 Fri, 15 Apr 2011 04:00:00 +0100 5306284 http://www.medworm.com/index.php?rid=5072188&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000653%2Fabstract%3Frss%3Dyes Summary: As essential polyunsaturated fatty acids (PUFAs) influence both inflammatory and depressive disorders, nutrition related treatment methods deserve great research interest. However, currently biological mechanisms underlying the depression modulating effects of the PUFA Omega-3 (ω-3) and Omega-6 (ω-6) derived eicosanoids (central nervous system messengers) are not fully established. Depression related naturally occurring cell death (apoptosis) is thought to be mediated by excitotoxicity and free radicals that appear in the brain immediately following any inflammatory or ischemic damage, and increases the likelihood of clinically defined depression. This review explores the hypothesis that the interaction between ω-6 and ω-3 derived eicosanoids plays a central role in control ov... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072188 Wed, 06 Apr 2011 23:00:00 +0100 5072188 http://www.medworm.com/index.php?rid=5443343&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141100063X%2Fabstract%3Frss%3Dyes Summary: Background & aims: Exercise induces adaptations in fat metabolism favourable to the treatment of obesity. However, time interval between meal and exercise alters substrate bioavailability and oxidation during exercise. The aim of this study was therefore to investigate the effect of time interval between food intake and exercise on substrate oxidation rates in obese and lean children.Methods: The metabolic responses to exercise of nine obese children (10.3 ± 1.8 years; %body fat: 36.1 ± 6.1) and seven lean children (9.2 ± 1.6 years; %body fat: 22.2 ± 4.1) were compared 1 h (time interval 1, TI1) and 3 h (TI3) after a standardized breakfast.Results: Despite significantly lower plasma glucose and insulin concentrations and large effect size suggesting a higher plasma F... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443343 Mon, 04 Apr 2011 04:00:00 +0100 5443343 http://www.medworm.com/index.php?rid=5306288&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000628%2Fabstract%3Frss%3Dyes Conclusions: As body proportionality indexes provide an assessment of body mass and fatness relative to length, we suggest that BMI and Wt/L ratio percentiles be added to weight and length growth curves as a routine intrauterine growth assessment at birth. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306288 Mon, 04 Apr 2011 04:00:00 +0100 5306288 http://www.medworm.com/index.php?rid=5306287&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000641%2Fabstract%3Frss%3Dyes Summary: Background & aims: Lifestyle interventions address primarily obese children, while interventions tailored to overweight but not obese children are scarce. The effectiveness of the lifestyle intervention “Obeldicks light” based on physical activity training, nutrition education, and behavior counseling for overweight children and their parents has been demonstrated by a randomized controlled trial. Here, we present the 12 months follow-up analysis of these children after end of intervention.Methods: Degree of overweight (BMI and SDS-BMI), waist circumference, skinfold thickness, bioimpedance analyses (BIA), and blood pressure were determined in 76 overweight (BMI>90th≤97th percentile) children (mean age 11.8 ± 1.8years, 67% females, mean BMI 24.3 ± 1.9 kg/m2) participa... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306287 Mon, 04 Apr 2011 04:00:00 +0100 5306287 http://www.medworm.com/index.php?rid=4879428&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000422%2Fabstract%3Frss%3Dyes Dr. John M. Kinney, professor of surgery at Columbia University’s College of Physicians & Surgeons from 1963 to 1987 and a distinguished researcher in the areas of traumatic care, metabolism and nutrition, died peacefully on Thursday, January 20, at his home in Sleepy Hollow, New York. He was 89. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879428 Thu, 31 Mar 2011 23:00:00 +0100 4879428 http://www.medworm.com/index.php?rid=5306293&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000616%2Fabstract%3Frss%3Dyes Summary: Background & aims: Inflammation is pivotal in all phases of atherosclerosis. Dietary options which lower inflammatory biomarkers would be an attractive strategy to reduce risk from cardiovascular diseases and cancer. Indeed, fruit and vegetable intake or fruit juice consumption is associated with health and wellness. However, there is a paucity of data examining the effect of orange juice on biomarkers of inflammation in healthy volunteers. We have previously conducted the first placebo-controlled randomized studies examining the effect of sterol fortified orange juice or sterol fortified reduced calorie orange juice beverage supplementation (2 g sterols/day) compared to Placebo OJ or Placebo OJBev, and showed significant benefits on the lipid profile as well as significant reduc... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306293 Fri, 25 Mar 2011 04:00:00 +0100 5306293 http://www.medworm.com/index.php?rid=5306285&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000598%2Fabstract%3Frss%3Dyes Summary: Background & aims: : Weight gain is an undesirable side effect of second-generation antipsychotics (SGAs). We performed this study to examine the influence of SGAs on resting energy expenditure (REE) and the relationship of REE to weight gain in adolescent patients.Methods: Antipsychotic-naïve or quasi-naïve ( (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306285 Fri, 25 Mar 2011 04:00:00 +0100 5306285 http://www.medworm.com/index.php?rid=5072189&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000604%2Fabstract%3Frss%3Dyes Summary: The modern Western-type diet is deficient in fruits and vegetables and contains excessive animal products, generating the accumulation of non-metabolizable anions and a lifespan state of overlooked metabolic acidosis, whose magnitude increases progressively with aging due to the physiological decline in kidney function. In response to this state of diet-derived metabolic acidosis, the kidney implements compensating mechanisms aimed to restore the acid-base balance, such as the removal of the non-metabolizable anions, the conservation of citrate, and the enhancement of kidney ammoniagenesis and urinary excretion of ammonium ions. These adaptive processes lower the urine pH and induce an extensive change in urine composition, including hypocitraturia, hypercalciuria, and nitrogen an... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072189 Fri, 25 Mar 2011 00:00:00 +0100 5072189 http://www.medworm.com/index.php?rid=5443342&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000550%2Fabstract%3Frss%3Dyes Summary: Background & aims: Major upper gastrointestinal surgery results in permanent alterations to the gastrointestinal tract, and previously been shown to impair nutritional status. The aim of this study was to assess long term nutritional status and quality of life in people having had major upper gastrointestinal surgery, and the relationship between the two measures.Methods: People having had major upper gastrointestinal surgery greater than 6 months ago were recruited. Nutrition assessment included weight, anthropometry, Subjective Global Assessment, dietary intake and assessment of gastrointestinal symptoms; quality of life was assessed using the EORTC QLQ-C30 questionnaire. Associations between nutritional status, type of surgery and quality of life were analysed.Results: Thirty p... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5443342 Mon, 21 Mar 2011 04:00:00 +0100 5443342 http://www.medworm.com/index.php?rid=5306292&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000549%2Fabstract%3Frss%3Dyes In this study, we investigated the effects of different dietary ratios of n-6/n-3 PUFAs on the brain structural development in mice and the expression of associated transcription factors. C57 BL/6J mice were fed with one of two categories of n-3 PUFA-containing diets (a flaxseed oil diet and a flaxseed/fish oil mixed diet) or an n-3 PUFA-deficient diet. For each of the n-3 PUFA diets, flaxseed oil or flaxseed/fish oil was combined with other oils to yield three different n-6/n-3 ratios, which ranged from 15.7:1 to 1.6:1. The feeding regimens began two months before mouse conception and continued throughout lactation for new pups. As compared with the n-3 PUFA-deficient diet, both the flaxseed oil n-3 PUFA diets and the flaxseed/fish oil n-3 PUFA diets significantly increased the expression... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306292 Mon, 21 Mar 2011 04:00:00 +0100 5306292 http://www.medworm.com/index.php?rid=5306283&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000574%2Fabstract%3Frss%3Dyes Conclusions: PS therapy appears to be of little value to MetS patients, likely due to its reduced intestinal cholesterol absorption. The efficacy of PS as hypocholesterolaemic agents is thus limited. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306283 Mon, 21 Mar 2011 04:00:00 +0100 5306283 http://www.medworm.com/index.php?rid=5306278&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000562%2Fabstract%3Frss%3Dyes Conclusions: A diet enriched with EPA, GLA, and anti-oxidants does not improve gas exchange or decrease the incidence of novel organ failures in critically ill septic patients with acute lung injury or ARDS. Patients treated with the EPA-GLA diet stayed in the ICU for less time, but we did not find any differences in infectious complications. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306278 Mon, 21 Mar 2011 04:00:00 +0100 5306278 http://www.medworm.com/index.php?rid=4879452&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000586%2Fabstract%3Frss%3Dyes We recently published in this journal a study on the differences in fat content and fatty acid proportions among colostrum, transitional, and mature milk samples from women delivering very preterm, preterm, and full term infants. Nevertheless, we did not explore whether fatty acid proportions correlated between samples collected at these different time points. In fact, to our knowledge, there is no study that has explored these correlations. We consider that the availability of this information would be of value to improve our knowledge on the regulation of fatty acid metabolism during lactation and to evaluate in what degree the fatty acid composition of colostrum reflects that of mature milk. Therefore, we decided to explore the correlations between PUFA percentages in colostrum, transit... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879452 Mon, 21 Mar 2011 00:00:00 +0100 4879452 http://www.medworm.com/index.php?rid=5306275&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000380%2Fabstract%3Frss%3Dyes Conclusions: EEN was associated with significantly shortened length of hospital stay and improved clinical outcomes. These findings reinforce the potential benefit of early oral nutrition in principle and as championed within enhanced recovery after surgery programmes, and such strategies deserve further research in the arena of upper GI surgery. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306275 Wed, 09 Mar 2011 05:00:00 +0100 5306275 http://www.medworm.com/index.php?rid=5306280&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000409%2Fabstract%3Frss%3Dyes Conclusions: Higher phospholipid proportions of OA relate to less IR, suggesting an added benefit of increasing olive oil intake within the Mediterranean diet. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306280 Mon, 07 Mar 2011 05:00:00 +0100 5306280 http://www.medworm.com/index.php?rid=5072209&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000392%2Fabstract%3Frss%3Dyes Conclusions: These results suggest that intestinal epithelial cells sustain the celiac inflammation, releasing AA when stimulated with gliadin and that DHA inhibits the AA release by these cells. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072209 Mon, 07 Mar 2011 00:00:00 +0100 5072209 http://www.medworm.com/index.php?rid=4879429&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000410%2Fabstract%3Frss%3Dyes Summary: Although insulin resistance in T2DM (type 2 diabetes mellitus) is usually referred to glucose and lipid metabolism, the question whether such a resistance affects also amino acid and protein metabolism is both relevant and not easy to be answered. Available data indicate a reduced response to insulin in the inhibition of proteolysis at low, near basal hormone levels, whereas such a response appears to be normal at high physiological doses. In most studies in T2DM subjects the stimulation of whole-body protein synthesis in the presence of hyperinsulinemia and euaminoacidemia appears to be normal, although one single study reported lower rates in male T2DM subjects with obesity. The response to insulin of plasma protein synthesis (albumin and fibrinogen) is also normal. However, som... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879429 Mon, 07 Mar 2011 00:00:00 +0100 4879429 http://www.medworm.com/index.php?rid=5306286&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000379%2Fabstract%3Frss%3Dyes Summary: Background & aims: To assess vitamin D (Vit-D) [serum 25-hydroxyvitamin D (25-OHD) concentrations] in children and young adults with perinatally acquired HIV compared to geographically similar healthy children.Methods: 25-OHD in children and young adults with HIV was compared to a healthy group. Vit-D deficiency and insufficiency were defined as 25-OHD (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5306286 Thu, 24 Feb 2011 05:00:00 +0100 5306286 http://www.medworm.com/index.php?rid=5072208&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000367%2Fabstract%3Frss%3Dyes Summary: Background & aims: Several olive oil phenolic compounds, such us oleuropein have attracted considerable attention because of their antioxidant activity, anti-atherosclerotic and anti-inflammatory properties. The aim of this study was to investigate the effects of oleuropein aglycone, a hydrolysis product of oleuropein, in a mouse model of carrageenan-induced pleurisy.Methods: Mice were anaesthetized and subjected to a skin incision at the level of the left sixth intercostals space. The underlying muscle was dissected and saline or saline containing 2% λ-carrageenan was injected into the pleural cavity.Results: Injection of carrageenan elicited an acute inflammatory response characterized by: infiltration of neutrophils in lung tissues (P  (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072208 Thu, 24 Feb 2011 00:00:00 +0100 5072208 http://www.medworm.com/index.php?rid=5072191&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141100032X%2Fabstract%3Frss%3Dyes Conclusions: Nutrition screening by nurses using the new PYMS score is feasible for paediatric inpatients, identifies children at risk of malnutrition and uses available resources efficiently. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072191 Mon, 21 Feb 2011 00:00:00 +0100 5072191 http://www.medworm.com/index.php?rid=5072190&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000343%2Fabstract%3Frss%3Dyes Summary: Background & aims: To examine the effect of malnutrition on clinical outcomes and healthcare resource use from initial diagnosis by a general practitioner (GP) in the UK.Methods: 1000 records of malnourished patients were randomly selected from The Health Improvement Network database and matched with a sample of 996 patients’ records with no previous history of malnutrition. Patients’ outcomes and resource use were quantified for six months following diagnosis.Results: Malnourished patients utilised significantly more healthcare resources (e.g. 18.90 versus 9.12 GP consultations; p  (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072190 Mon, 21 Feb 2011 00:00:00 +0100 5072190 http://www.medworm.com/index.php?rid=5072202&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000355%2Fabstract%3Frss%3Dyes Conclusions: The large overall increase in numbers of HPN patients suggests that a national strategy needs to be developed for the management of chronic IF. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072202 Fri, 18 Feb 2011 00:00:00 +0100 5072202 http://www.medworm.com/index.php?rid=5072203&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000331%2Fabstract%3Frss%3Dyes Conclusions: Our explorative data using whole blood microanalysis confirm the progressive increase of long-chain polyunsaturated FA levels from the mothers towards cord and then infant blood. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072203 Mon, 14 Feb 2011 00:00:00 +0100 5072203 http://www.medworm.com/index.php?rid=5072197&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000318%2Fabstract%3Frss%3Dyes Conclusions: Albumin synthesis rates in hypoalbuminemic critically ill children are high but were not upregulated through nutrient supply, and in septic adolescents are unaffected by insulin. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072197 Mon, 14 Feb 2011 00:00:00 +0100 5072197 http://www.medworm.com/index.php?rid=5072198&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000306%2Fabstract%3Frss%3Dyes Conclusions: Surgically ill patients with adequate plasma PLP concentration at admission showed improved blood glucose response at day 7. Higher plasma PLP at admission was a major contributing factor in the reduction of glucose concentration in critically ill surgical patients with deficient vitamin B-6 status. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072198 Tue, 01 Feb 2011 00:00:00 +0100 5072198 http://www.medworm.com/index.php?rid=4466892&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000161%2Fabstract%3Frss%3Dyes The European Society for Clinical Nutrition and Metabolism and the Editors would like to thank all of the reviewers listed below who do such excellent work for Clinical Nutrition. Without their knowledge, skill and dedication, the journal would not achieve the high standards of peer review that we seek to maintain at all times. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4466892 Tue, 01 Feb 2011 00:00:00 +0100 4466892 http://www.medworm.com/index.php?rid=5072196&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000288%2Fabstract%3Frss%3Dyes Summary: Background & aims: Treatment measures for constipation in children are often not satisfactory. The aim was to assess the efficacy of glucomannan (GNN) as a sole treatment for functional constipation.Methods: Children aged 3–16 years with functional constipation according to Rome III criteria were randomly assigned to receive GNN (2.52 g/d) or placebo for 4 weeks.Results: Of the 80 children, 72 (90%) completed the study. The primary outcome, treatment success (≥3 stools per week with no soiling), was similar in the GNN (n = 36) and placebo (n = 36) groups (relative risk 0.95, 95% CI 0.6 to 1.4). In the GNN group, the stool consistency score was higher at week 1 (P  (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072196 Fri, 28 Jan 2011 00:00:00 +0100 5072196 http://www.medworm.com/index.php?rid=5072207&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000239%2Fabstract%3Frss%3Dyes Summary: Background & aims: Enteroendocrine cells are thought to directly sense nutrients via α-gustducin coupled taste receptors (originally identified in the oral epithelium) to modulate the secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY).Methods: We measured mRNA expression of α-gustducin and T1R3 along the human gut; immunohistochemistry was used to confirm co-localization with GLP-1. Functional implication of sweet taste receptors in glucose-stimulated secretion of GLP-1 and PYY was determined by intragastric infusion of glucose with or without lactisole (a sweet taste receptor antagonist) in 16 healthy subjects.Results: α-gustducin was expressed in a region-specific manner (predominantly in the proximal gut and less in ileum and colon, P  (Source: Clinical Nutri... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072207 Thu, 27 Jan 2011 00:00:00 +0100 5072207 http://www.medworm.com/index.php?rid=5072204&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000264%2Fabstract%3Frss%3Dyes Conclusions: Sarcoidosis patients might benefit from the use of antioxidants, such as quercetin, to reduce the occurring oxidative stress as well as inflammation. The effects of long-term use of antioxidant supplementation in sarcoidosis, using e.g. quercetin, on improvement of lung function remain to be investigated. (www.clinicaltrials.gov; NCT-00402623). (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072204 Thu, 27 Jan 2011 00:00:00 +0100 5072204 http://www.medworm.com/index.php?rid=5072200&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141100029X%2Fabstract%3Frss%3Dyes Summary: Background & aim: Oxidized LDL (oxLDL) is a highly immunogenic particle that plays a key role in the development of atherosclerosis. Some data suggest a protective role of OxLDL autoantibodies (OLAB) in atherosclerosis. Our aim was to assess the effect of olive oil polyphenols on the immunogenicity of oxLDL to autoantibody generation.Methods: In a crossover, controlled trial, 200 healthy men were randomly assigned to 3-week sequences of 25 mL/day of 3 olive oils with high (366 mg/kg), medium (164 mg/kg), and low (2.7 mg/kg) phenolic content.Results: Plasma OLAB concentration was inversely associated with oxLDL (p  (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072200 Thu, 27 Jan 2011 00:00:00 +0100 5072200 http://www.medworm.com/index.php?rid=5072199&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000240%2Fabstract%3Frss%3Dyes Conclusion: Only one in four undernourished hospital patients meets the predefined protein and energy requirements on the fourth day of admission. Nausea, cancer, acute infections, BMI, age, chronic lung disease and tube feeding were identified as predictors for achieving protein and energy intake. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072199 Thu, 27 Jan 2011 00:00:00 +0100 5072199 http://www.medworm.com/index.php?rid=5072195&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000276%2Fabstract%3Frss%3Dyes Conclusions: Among elderly patients with a hip fracture, a multidisciplinary postoperative approach of nutritional care was associated with an increase of energy and protein intake during hospitalisation. After three months follow-up there were fewer malnourished patients in the intervention group, and the decline in quality of life was lower than in the control group. There were no advantages of multidisciplinary nutritional care on body cell mass. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072195 Thu, 27 Jan 2011 00:00:00 +0100 5072195 http://www.medworm.com/index.php?rid=5072192&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000252%2Fabstract%3Frss%3Dyes This study aims at clarifying body composition changes in healthy elderly subjects, and evaluating the impact of physical activity on these changes.Methods: In 1999, 213 subjects ≥ 65 years recruited through advertisements underwent assessment of health state, energy expenditure by physical activity, body composition by bioimpedance analysis and body cell mass by total body potassium. In 2008, 112 of them repeated these assessments with additional determination of Barthel index, Mini Mental State Examination and Geriatric Depression Score.Results: Lean tissues decreased in both genders (p  (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072192 Thu, 27 Jan 2011 00:00:00 +0100 5072192 http://www.medworm.com/index.php?rid=5072206&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000070%2Fabstract%3Frss%3Dyes Conclusions: In spite of the different composition of proteins in the enteral diets tested, the absorption of leucine, even though slightly higher in the malnourished state, is similar in both of them. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072206 Tue, 18 Jan 2011 00:00:00 +0100 5072206 http://www.medworm.com/index.php?rid=5072201&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000082%2Fabstract%3Frss%3Dyes Conclusions: WPS improves hepatic steatosis and plasma lipid profiles in obese non diabetic patients, without adverse effects on glucose tolerance or creatinine clearance.Trial Number: NCT00870077, ClinicalTrials.gov (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072201 Tue, 18 Jan 2011 00:00:00 +0100 5072201 http://www.medworm.com/index.php?rid=5072205&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000045%2Fabstract%3Frss%3Dyes Summary: Background & aims: Gut ischemia-reperfusion (I/R) is considered an important mechanism underlying multiple organ failure after severe surgical insults. We previously demonstrated an enteral diet enriched with whey-hydrolyzed peptide, fermented milk, and isomaltulose to have anti-inflammatory effects in a concanavalin A-induced hepatitis model. Here, we investigated whether the immune-modulating diet (IMD), could prevent systemic inflammation, thereby improving survival in a gut I/R model.Methods: Mice were randomized into control enteral diet (n = 58) or IMD (n = 56) for 2 weeks’ feeding. In experiment 1, 39 mice underwent 45 min of gut ischemia, and were sacrificed at 3 h after reperfusion to collect blood samples. Plasma IL-6 and glucose levels were measured. In experime... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072205 Wed, 12 Jan 2011 00:00:00 +0100 5072205 http://www.medworm.com/index.php?rid=5072193&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000021%2Fabstract%3Frss%3Dyes Conclusions: We conclude that 8 g of SAF daily improved glycemia, inflammation, and blood lipids, indicating that small changes in dietary fat quality may augment diabetes treatments to improve risk factors for diabetes-related complications. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072193 Wed, 12 Jan 2011 00:00:00 +0100 5072193 http://www.medworm.com/index.php?rid=4879447&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000069%2Fabstract%3Frss%3Dyes Summary: Background & aims: Arginine infusion has been demonstrated to increase wound protein deposition; however, the effects of its enteral supplementation on wound cell proliferation have not been studied.Methods: Skin donor wound was created on the back of rabbits. The rabbits were randomly assigned to receive a control enteral diet, or the control enteral diet with supplemental arginine. On day 5 l-[ring-13C6]phenylalanine and d-[U-13C6]glucose were infused to measure the fractional synthetic rates of DNA (reflecting cell proliferation) and protein in the wound.Results: In the arginine group (n = 6) plasma arginine concentration was increased to 2.8 fold that in the control group (n = 8), which was a less increase than that of 6.4 fold for ornithine. Wound DNA fractional synthetic... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879447 Wed, 12 Jan 2011 00:00:00 +0100 4879447 http://www.medworm.com/index.php?rid=4879442&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561411000033%2Fabstract%3Frss%3Dyes Conclusions: Magnesium status was influenced by kidney depuration and was altered in patients with type 2 diabetes, and magnesium showed to play an important role in blood glucose control. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879442 Wed, 12 Jan 2011 00:00:00 +0100 4879442 http://www.medworm.com/index.php?rid=4879436&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002190%2Fabstract%3Frss%3Dyes Conclusions: Inadequate nutritional intake is common, and patient factors contributing to poor intake should be considered in designing nutritional interventions. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879436 Fri, 07 Jan 2011 00:00:00 +0100 4879436 http://www.medworm.com/index.php?rid=4879445&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002104%2Fabstract%3Frss%3Dyes Conclusions: Higher calcium and vitamin D intake at a breakfast meal acutely increased postprandial FOR and DIT over two successive meals, and reduced spontaneous energy intake in the subsequent 24 h period.Australian New Zealand Clinical Trials Registry (ANZCTR) number: ACTRN12609000418279. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879445 Wed, 05 Jan 2011 00:00:00 +0100 4879445 http://www.medworm.com/index.php?rid=5072194&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002177%2Fabstract%3Frss%3Dyes Summary: Background & aims: Detection and notification of malnutrition are essential to adopt a support plan and take costs into account. The aim of this study was to describe how often discharge sheets from Internal Medicine (IM) units include malnutrition among diagnoses (notification frequency) using the International Classification of Diseases, 9th Revision Clinical Modification -ICD-9. Factors associated with this diagnosis and its prognostic implications are also assessed.Material and methods: The Minimum Basic Data Set from the Spanish hospitals (Ministry of Health and Consumer Affairs) was revised, and patients with diagnosis of malnutrition (ICD-9: 260–263.9) were identified.Results: 1,567,659 patients were analysed (21,804–1.4%- with malnutrition). These patients were older (... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=5072194 Mon, 03 Jan 2011 00:00:00 +0100 5072194 http://www.medworm.com/index.php?rid=4879451&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002219%2Fabstract%3Frss%3Dyes We were pleased by the report from Cullis et al. on their positive experience with regard to the use of taurolidine locks to prevent catheter-related bloodstream infections (CRBSI) in several high-risk patients of their Scottish HPN population. Unfortunately, in this condensed report there is some information missing, such as the type of control (low-dose heparin?), the volume of the lock, whether this was withdrawn or infused, and if so, if there were any side effects related to the infusion. Nevertheless, although this concerns a small non-randomized retrospective study the findings are of interest, also because the authors used a formulation that differs from our 2% taurolidine solution (TaurosSept) in several ways. First, their formulation (Taurolock) has a lower concentration of taur... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879451 Mon, 03 Jan 2011 00:00:00 +0100 4879451 http://www.medworm.com/index.php?rid=4879450&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002207%2Fabstract%3Frss%3Dyes We read with great interest the paper by Bisseling et al. which demonstrates that taurolidine lock (Taurocept®) is an effective means of reducing the incidence of catheter-related bloodstream infections (CRBSI) in patients on home parenteral nutrition. We have been maintaining clinical and microbiological records of our HPN patients since 2000 and have been using taurolidine lock (TauroLock™) with heparin since 2002. It has been our policy to add taurolidine lock to patients who have experienced recurrent CRBSI. Prior to publication of your paper, we had performed a retrospective analysis of our results to establish whether taurolidine lock was useful. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879450 Mon, 03 Jan 2011 00:00:00 +0100 4879450 http://www.medworm.com/index.php?rid=4879434&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002220%2Fabstract%3Frss%3Dyes Conclusion: Healthy young males fed a HP diet improved reaction time. No adverse effects of the HP diet were observed.This trial was registered at www.clinicaltrials.govas NCT00621231. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879434 Mon, 03 Jan 2011 00:00:00 +0100 4879434 http://www.medworm.com/index.php?rid=4466916&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002141%2Fabstract%3Frss%3Dyes This is probably the best book ever written introducing human metabolism. Keith N. Frayn, professor of Human Metabolism at the University of Oxford, UK is the sole author of this textbook. To the scientific field of nutrition and metabolism., Professor Frayn is a well known and very respected contributor to the current understanding of in particular fat metabolism, where his research focus has been over the last 20 years or so. But Professor Frayn has a very solid background from his early days in the MRC Trauma Unit in Manchester headed by Professor Barry Stoner. This unit fostered several of the leading clinical scientists in the field of nutrition and metabolism in the UK. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4466916 Mon, 03 Jan 2011 00:00:00 +0100 4466916 http://www.medworm.com/index.php?rid=4879444&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002189%2Fabstract%3Frss%3Dyes Conclusions: These findings indicate that carotenoids may be important factors in the prevention of metabolic syndrome in nonsmokers, but further studies are required in smokers. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879444 Wed, 22 Dec 2010 00:00:00 +0100 4879444 http://www.medworm.com/index.php?rid=4879435&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002153%2Fabstract%3Frss%3Dyes The objective of these guidelines is to develop a tool for identifying and managing elderly subjects who are malnourished or at risk of malnutrition. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879435 Wed, 22 Dec 2010 00:00:00 +0100 4879435 http://www.medworm.com/index.php?rid=4879433&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002165%2Fabstract%3Frss%3Dyes Conclusion: Homocysteine lowering in dementia patients did not significantly reduce global cognitive decline. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879433 Wed, 22 Dec 2010 00:00:00 +0100 4879433 http://www.medworm.com/index.php?rid=4879443&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141000213X%2Fabstract%3Frss%3Dyes Conclusion: Patients fed by NG tube and deemed at risk of RH are more likely to develop RH than patients fed by PN. The higher risk with NG feeding may be due to the incretin effect from absorption of glucose. The UK guidelines lack specificity. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879443 Mon, 13 Dec 2010 00:00:00 +0100 4879443 http://www.medworm.com/index.php?rid=4466893&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002128%2Fabstract%3Frss%3Dyes Xavier Leverve passed away on November 8, following a terrible disease against which he struggled since the beginning of the year with admirable courage and control. He was sixty year old. Xavier Leverve personality exhibited multiple facets which are exceptionally combined in a single man: he was a brilliant scientist, giving rise to new concepts, and for whom the integrated approach to biology was innate; he never separated his scientific activity from his doctor questioning; his political vision on what could and should become our discipline was an acute and a unique insight; his Culture, mind openness and interest in human being made him a great humanist; his charisma and his love of life have made countless friends around the world. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4466893 Thu, 02 Dec 2010 00:00:00 +0100 4466893 http://www.medworm.com/index.php?rid=4231595&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002037%2Fabstract%3Frss%3Dyes ESPEN’s educational activities have constantly been strengthened over the last decade. We have developed a web-based life-long learning (LLL) system designed to assist health care professionals to improve their skills in nutritional assessment and care of patients. The massive increase of courses participants confirms the need for such an action. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4231595 Wed, 01 Dec 2010 00:00:00 +0100 4231595 http://www.medworm.com/index.php?rid=4879441&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002098%2Fabstract%3Frss%3Dyes Summary: Background & aims: Recently, studies have reported that sesame oil lowered blood pressure and improved antioxidant status in hypertensive and diabetic-hypertensive patients. The aim of this study was to evaluate the effectiveness of sesame oil with anti-diabetic (glibenclamide) medication as combination therapy in mild-to moderate diabetic patients.Methods: This open label study included sixty type 2 diabetes mellitus patients divided into 3 groups, receiving sesame oil (n = 18), 5 mg/day (single dose) of glibenclamide (n = 20), or their combination (n = 22). The patients were supplied with sesame oil [BNB Sesame oilTM] except glibenclamide group, and instructed to use approximately 35 g of oil/day/person for cooking, or salad preparation for 60 days. 12 h-fasting venous ... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879441 Mon, 29 Nov 2010 00:00:00 +0100 4879441 http://www.medworm.com/index.php?rid=4879430&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002116%2Fabstract%3Frss%3Dyes Summary: Nutritional support, as complete enteral tube feeding, is needed by many paediatric patients and must provide sufficient nutrients for normal growth and development. Enteral feeds contain the parent essential fatty acids, linoleic acid and α-linolenic acid, but often do not contain n-3 long-chain polyunsaturated fatty acids. Available data suggest that biosynthesis of eicosapentaenoic acid and docosahexaenoic acid from α-linolenic acid is low in humans and varies between individuals. Long-term enteral feeding with formulae devoid of eicosapentaenoic acid and docosahexaenoic acid may result in low levels in plasma and tissues, potentially affecting immune and neurological function. Currently there is insufficient evidence to define the quantitative eicosapentaenoic acid and doco... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879430 Mon, 29 Nov 2010 00:00:00 +0100 4879430 http://www.medworm.com/index.php?rid=4879449&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002001%2Fabstract%3Frss%3Dyes Dear Editor, Cereda et al. have raised an important issue regarding elderly patients in the postoperative period of surgical treatment for hip fracture In fact it has been demonstrated that pressure ulcers can develop early –in the first two days– in the postoperative period in these patients, and that nutritional supplements can slightly delay this onset. Furthermore, a recent study which included 478 patients with hip fracture has shown that an intensive protocol that included nutritional supplementation among other measures was able to reduce the development of hospital-acquired pressure ulcers. However those studies included both undernourished and normonourished patients, and it has been extensively shown that malnutrition is the most strongly associated factor with a higher rate... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879449 Mon, 22 Nov 2010 00:00:00 +0100 4879449 http://www.medworm.com/index.php?rid=4879440&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002086%2Fabstract%3Frss%3Dyes Conclusions: Our study shows that early nutrition support reduces ICU mortality in critically ill patients, although it does not demonstrate any influence over nosocomial infection in the current practice in intensive care. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879440 Mon, 22 Nov 2010 00:00:00 +0100 4879440 http://www.medworm.com/index.php?rid=4879439&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002025%2Fabstract%3Frss%3Dyes Summary: Background & aims: Canola oil is a variety of rapeseed oil low in erucic acid ( (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879439 Fri, 12 Nov 2010 00:00:00 +0100 4879439 http://www.medworm.com/index.php?rid=4879448&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001998%2Fabstract%3Frss%3Dyes We read with great interest the article by Botella-Carretero et al. The Authors have demonstrated that in normally or mildly undernourished elderly, submitted to surgery for hip fracture, perioperative high-protein nutritional support is associated with less postoperative complications. Surprisingly, no incidence data on pressure ulcers (PUs) was provided. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879448 Tue, 09 Nov 2010 00:00:00 +0100 4879448 http://www.medworm.com/index.php?rid=4879446&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410002013%2Fabstract%3Frss%3Dyes Summary: Background & aims: Involvement of insulin in diabetes-associated liver triglyceride deposition and its potential pathways remain incompletely defined. SIRT1 may negatively modulate lipogenesis and liver triglyceride accumulation, involving AMP-activated protein kinase (AMPK) activation. In streptozotocin-diabetic rats, we hypothesized that insulin negatively modulates liver SIRT1 and activates AMPK-inhibited lipogenic mediators leading to triglyceride accumulation. The impact of insulin deprivation (INS−) and replacement (INS+) on liver inflammation and mitochondrial oxidative capacity (also potentially regulating triglyceride deposition) was also measured.Methods: Streptozotocin-diabetic rats under chronic (8-week) INS− and INS+.Results: Compared to INS− (P  (Source: Clini... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879446 Tue, 09 Nov 2010 00:00:00 +0100 4879446 http://www.medworm.com/index.php?rid=4879437&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001913%2Fabstract%3Frss%3Dyes Summary: Background & aims: Bioimpedance spectroscopy (BIS) offers the possibility to perform rapid estimates of fluid distribution and body composition. Few studies, however, have addressed the precision and biological variation in a pediatric population. Our objectives were to evaluate precision, variation within- and between-days for the BIS-determined parameters total body fluid, extra-cellular fluid, intra-cellular fluid, body cell mass, fat-free mass, extra-cellular resistance, intra-cellular resistance and percentage body fat using a Xitron 4200.Methods: All 133 children (81 boys, 52 girls; 2.4–14.9 years) had one series measured on day one (precision population). Forty-four children had a second series on day one (within-day sub-population). Thirty-two children had a series measu... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879437 Wed, 27 Oct 2010 23:00:00 +0100 4879437 http://www.medworm.com/index.php?rid=4646778&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001895%2Fabstract%3Frss%3Dyes The experience of Dr. Diamanti is in line with our conclusions and confirms, in this rare disease where only few data are available, that gastrostomy is efficient and well tolerated. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646778 Sun, 24 Oct 2010 23:00:00 +0100 4646778 http://www.medworm.com/index.php?rid=4646777&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001901%2Fabstract%3Frss%3Dyes In conclusion, our experience confirms efficacy and safety of enteral feeding through gastrostomy in individuals with Duchenne. Due to the beneficial effects of this nutritional approach, the placement of a gastrostomy should be planned at earlier stages of the disease process, before the risk associated with anaesthesia in those with compromised respiratory capacity develops. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646777 Sun, 24 Oct 2010 23:00:00 +0100 4646777 http://www.medworm.com/index.php?rid=4879432&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001883%2Fabstract%3Frss%3Dyes Summary: Background & aims: A food quality control and improvement permanent process was initiated in 1999. To evaluate the food service evolution, protein–energy needs coverage were compared in 1999 and 2008 with the same structure survey in all hospitalized patients receiving 3 meals/day.Methods: Nutritional values of food provided, consumed and wasted over 24h including non-exclusive nutritional support were calculated individually. Nutritional needs were estimated as 110% of Harris–Benedict formula for energy and 1.2 or 1.0g protein/kg/day for patients (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879432 Tue, 12 Oct 2010 23:00:00 +0100 4879432 http://www.medworm.com/index.php?rid=4879431&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001871%2Fabstract%3Frss%3Dyes Conclusions: The study proved that postoperative immunomodulating enteral nutrition should be the treatment of choice in malnourished surgical cancer patients.The Clinical Trials Database registry number: NCT00576940. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879431 Tue, 12 Oct 2010 23:00:00 +0100 4879431 http://www.medworm.com/index.php?rid=4879438&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS026156141000186X%2Fabstract%3Frss%3Dyes Conclusions: Muscle depletion hardly affects health status in COPD. Physiological correlations, however, do exist, pointing to severe disease, especially emphysema, and female sex as important concomitant factors. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4879438 Sun, 10 Oct 2010 23:00:00 +0100 4879438 http://www.medworm.com/index.php?rid=4646773&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001858%2Fabstract%3Frss%3Dyes Conclusion: Oral tributyrin increased plasma butyrate in the portal vein and attenuated liver injury in endotoxemic rats. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646773 Sun, 10 Oct 2010 23:00:00 +0100 4646773 http://www.medworm.com/index.php?rid=4646759&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001822%2Fabstract%3Frss%3Dyes Summary: Background & aims: To establish whether probiotic supplemented dietary counselling influences maternal anthropometric measurements during and after pregnancy.Methods: At the first trimester of pregnancy 256 women were randomly assigned to receive nutrition counselling to modify dietary intake according to current recommendations or as controls; dietary intervention groups were further randomized to receive probiotics Lactobacillus rhamnosus GG (ATCC 53103) and Bifidobacterium lactis (diet/probiotics) or placebo (diet/placebo) capsules in a double-blind manner, whilst the controls received placebo (control/placebo). The intervention lasted until the end of exclusive breastfeeding for up to six months.Results: The risk of central adiposity defined as waist circumference 80 cm or mo... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646759 Sun, 10 Oct 2010 23:00:00 +0100 4646759 http://www.medworm.com/index.php?rid=4646758&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001846%2Fabstract%3Frss%3Dyes Conclusions: Successful EN may be associated with a reduction in infectious complications, particularly after 96h of ICU admission. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646758 Sun, 10 Oct 2010 23:00:00 +0100 4646758 http://www.medworm.com/index.php?rid=4646756&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001834%2Fabstract%3Frss%3Dyes Summary: Background & aims: Among all muscle function tests, measurement of hand grip strength has gained attention as a simple, non-invasive marker of muscle strength of upper extremities, well suitable for clinical use. This review outlines the prognostic relevance of grip strength in various clinical and epidemiologic settings and investigates its suitability as marker of nutritional status in cross-sectional as well as intervention studies.Methods: Studies investigating grip strength as prognostic marker or nutritional parameter in cross-sectional or intervention studies were summarized.Results and conclusions: Numerous clinical and epidemiological studies have shown the predictive potential of hand grip strength regarding short and long-term mortality and morbidity. In patients, impai... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646756 Sun, 10 Oct 2010 23:00:00 +0100 4646756 http://www.medworm.com/index.php?rid=4646762&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001809%2Fabstract%3Frss%3Dyes Conclusions: The results of this study confirm the reliability of SCOFF-F as a screening and diagnostic-facilitating test for eating disorders in a French-speaking female patient population. SCOFF-F should help professionals in clinical nutrition to achieve earlier diagnosis and care of eating disorder patients. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646762 Sun, 03 Oct 2010 23:00:00 +0100 4646762 http://www.medworm.com/index.php?rid=4646760&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001810%2Fabstract%3Frss%3Dyes Conclusions: Glutamine and lipid supplementation did not prolong the GE of CCD but did ‘blunt’ postprandial glucose and insulin responses, independent of GLP-1 concentrations. Registered under ClinicalTrials.gov Identifier no. NCT00943020. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646760 Sun, 03 Oct 2010 23:00:00 +0100 4646760 http://www.medworm.com/index.php?rid=4646776&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001779%2Fabstract%3Frss%3Dyes We welcome Dr. Nakona’s comments relating to our paper. He criticizes our methods for failing to disclose the measurement technique for serum albumin in our study. Our study used a dye-binding method using bromocresol purple (BCP) to measure serum albumin. This was the standard laboratory test for serum albumin at our institution during the study period. We agree that serum albumin measurements should always be interpreted in the context of the assays used and, in particular, the normal reference range for that laboratory. It is widely acknowledged that published studies, especially where malnutrition and risk of complications is stratified based on specific serum albumin threshold levels, must specify the assay method used. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646776 Mon, 27 Sep 2010 23:00:00 +0100 4646776 http://www.medworm.com/index.php?rid=4646775&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001780%2Fabstract%3Frss%3Dyes Hip fracture is associated with high mortality and morbidity. Malnutrition has been reported to an important predictor of clinical outcomes. Serum albumin level and blood total lymphocyte count (TLC) are considered to be the simple, but reliable markers indicating the patients’ nutritional status, and often employed in various clinical settings including hip fracture. Recently O’Daly et al. in the recent issue of Clinical Nutrition, studied the significance of these two markers as the predictors of outcome in hip fractured patients. They defined protein energy malnutrition (PEM) as serum albumin level below 3.5 g/dl and TLC below 1500/mm3. Patients with both parameters below the cut-off had higher one year mortality than those with both values above the cut-off (odds ratio; 4.6). Cox... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646775 Mon, 27 Sep 2010 23:00:00 +0100 4646775 http://www.medworm.com/index.php?rid=4646772&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001755%2Fabstract%3Frss%3Dyes Conclusions: Ileum resections affect the biliary Ph and BA composition, which could increase bile lithogenicity but do not seem to affect biliary duct anatomy. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646772 Mon, 27 Sep 2010 23:00:00 +0100 4646772 http://www.medworm.com/index.php?rid=4646767&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001767%2Fabstract%3Frss%3Dyes We examined associations between the first-week energy and protein intake and clinical outcomes in medical ICU (MICU) patients who survived at least seven days.Methods: We retrospectively studied 295 patients admitted to a 28-bed MICU between 2005 and 2007. High and low energy delivery (ED) and protein delivery (PD) were defined as having a mean daily intake relative to recommendation at ≥ 60% and (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646767 Mon, 27 Sep 2010 23:00:00 +0100 4646767 http://www.medworm.com/index.php?rid=4646761&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001603%2Fabstract%3Frss%3Dyes Conclusions: Approximately half of the eating disability was not due to dementia. Eating disability may be minimized by treating comorbidities and creating supportive social and physical nursing home environments. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646761 Mon, 27 Sep 2010 23:00:00 +0100 4646761 http://www.medworm.com/index.php?rid=4646757&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001792%2Fabstract%3Frss%3Dyes Conclusion: An effective protection against IRI by amino acid supplementation has been demonstrated in experimental and several clinical studies. However, further clinical trials are warranted to identify the most promising approach for a routine clinical application. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646757 Mon, 27 Sep 2010 23:00:00 +0100 4646757 http://www.medworm.com/index.php?rid=4646770&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001585%2Fabstract%3Frss%3Dyes Conclusions: Minor allele carriers for E298D and i19342 have an impaired postprandial MEF and increased oxidative stress. Our results both provide insight into the higher risk of CVD attributed to E298D and identify variants that affect MEF in a healthy population. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646770 Mon, 13 Sep 2010 23:00:00 +0100 4646770 http://www.medworm.com/index.php?rid=4646769&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001548%2Fabstract%3Frss%3Dyes Conclusions: Our results suggest that NS treatment, reducing the development of inflammation and tissue injury, may be useful in the treatment of SCI. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646769 Mon, 13 Sep 2010 23:00:00 +0100 4646769 http://www.medworm.com/index.php?rid=4646763&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001573%2Fabstract%3Frss%3Dyes Summary: Background & aims: Epidemiologic studies have suggested beneficial effects of flavonoids on cardiovascular disease. Cocoa and particularly dark chocolate are rich in flavonoids and recent studies have demonstrated blood pressure lowering effects of dark chocolate. However, limited data are available on the association of chocolate consumption and the risk of coronary heart disease (CHD). We sought to examine the association between chocolate consumption and prevalent CHD.Methods: We studied in a cross-sectional design 4970 participants aged 25–93 years who participated in the National Heart, Lung, and Blood Institute (NHLBI) Family Heart Study. Chocolate intake was assessed through a semi-quantitative food frequency questionnaire. We used generalized estimating equations to esti... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646763 Mon, 13 Sep 2010 23:00:00 +0100 4646763 http://www.medworm.com/index.php?rid=4646766&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001597%2Fabstract%3Frss%3Dyes Summary: Background & aims: Old patients seldom reach their energy requirements. The effects of an oleic acid rich formula on energy intake and appetite were studied.Methods: Recently admitted geriatric patients (n = 71), likely to stay >1 week were randomised to receive 30 ml of a fat emulsion (Calogen®) 3 times daily, i.e., 420 kcal, at the regular medication rounds (intervention group (IG)) or to standard care (control group (CG)). Food intake and self-rated appetite were registered at baseline, i.e., 2–3 days after admission and on day 8 or the day prior to discharge. Nutritional risk screening (NRS) 2002, serum lipids and fatty acid profiles were analysed.Results: Fifty-one subjects fulfilled the study, i.e., 24 in the IG (83 ± 7 y) and 27 controls (85 ± 7 y). NRS showe... Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646766 Thu, 09 Sep 2010 23:00:00 +0100 4646766 http://www.medworm.com/index.php?rid=4646771&cid=s_35405_28_f&fid=35405&url=http%3A%2F%2Fwww.clinicalnutritionjournal.com%2Farticle%2FPIIS0261561410001512%2Fabstract%3Frss%3Dyes Conclusions: Results suggest that promoter −204A > C variant is associated with enhanced CYP7A1 activity. Increased intestinal bile acids and ensuing more efficient cholesterol absorption might explain why C-allele carriers show enhanced cholesterol lowering and increased feedback cholesterol synthesis to PS intervention. (Source: Clinical Nutrition) Clinical Nutrition journals http://www.medworm.com/rss/comments.php?id=4646771 Thu, 26 Aug 2010 23:00:00 +0100 4646771