MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Clinical Research in Cardiology' source. Wed, 08 Feb 2012 09:32:35 +0100 http://www.medworm.com/index.php?rid=5659535&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa5186v3334045m23%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-2DOI 10.1007/s00392-012-0418-4Authors M. Forkmann, Department of Medicine and Cardiology, Heart Center Dresden, University of Technology Dresden, Dresden, GermanyS. M. Tugtekin, Department of Cardiac Surgery, Heart Center Dresden, University of Technology Dresden, Dresden, GermanyR. H. Strasser, Department of Medicine and Cardiology, Heart Center Dresden, University of Technology Dresden, Dresden, GermanyH. Schrötter, Department of Medicine and Cardiology, Heart Center Dresden, University of Technology Dresden, Dresden, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5659535 Wed, 01 Feb 2012 17:10:02 +0100 5659535 http://www.medworm.com/index.php?rid=5659536&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh838012828j07703%2F Discussion  We previously showed that upon repeated administration, the preconditioning-like effects of GTN are attenuated. The present data demonstrate a gradient in the extent of protection afforded by the two nitrates, suggesting that PETN-induced preconditioning is maintained after prolonged administration in a human in vivo model of endothelial dysfunction induced by ischemia. Using isolated human endothelial cells, we propose a mechanistic explanation for this observation based on differential effects of GTN versus PETN on the activity of mitochondrial aldehyde dehydrogenase. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-012-0412-xAuthors Monica Lisi, Department of Clinical Medicine and Immunological Sciences, University of Si... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5659536 Wed, 01 Feb 2012 17:10:00 +0100 5659536 http://www.medworm.com/index.php?rid=5659537&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmn558734g3724v21%2F Conclusion  Zotarolimus coated balloons and stents were found to effectively reduce neointimal proliferation in the porcine coronary model. Inflammation scores were significantly reduced after treatment with the coated balloon. Zotarolimus balloon coating might be a novel option in preventing and treating restenosis. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-012-0415-7Authors Bodo Cremers, Department of Internal Medicine III, University of Saarland, 66421 Homburg/Saar, GermanyJohn L. Toner, Abbott Laboratories, Abbott Park, IL, USALewis B. Schwartz, Abbott Laboratories, Abbott Park, IL, USARandolf von Oepen, Abbott Laboratories, Abbott Park, IL, USAUlrich Speck, Department of Radiology, Campus Charité Mitte, Humboldt University, ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5659537 Tue, 31 Jan 2012 16:47:57 +0100 5659537 http://www.medworm.com/index.php?rid=5647510&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu26r542682668126%2F Severe left main coronary stenosis in a young female patient, 6 years after mediastinal radiation therapy for non-Hodgkin lymphoma: assessment by coronary angiography and intravascular ultrasound Content Type Journal ArticleCategory Letter to the EditorsPages 1-4DOI 10.1007/s00392-012-0413-9Authors Grigorios Korosoglou, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyArnt V. Kristen, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyMartin Andrassy, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyHugo A. Katus, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyStefan E. Hardt, ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5647510 Fri, 27 Jan 2012 17:53:45 +0100 5647510 http://www.medworm.com/index.php?rid=5647512&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj866637788p26778%2F Conclusions  For adequate risk assessment in ULMCA patients, consideration of both comorbidities and coronary anatomic complexity, is essential. A combination of angiographic and clinical risk scores improves the prognostic value for the prediction of 1-year MACE risk and is superior to stand-alone scores. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-012-0417-5Authors Jan-Malte Sinning, Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Rheinische Friedrich-Wilhelms-Universität, Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, GermanyViktoria Stoffel, Medizinische Klinik und Poliklinik II, Universitätsklinikum Bonn, Rheinische Friedrich-Wilhelms-Universität, Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, GermanyEberhard Grube, M... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5647512 Fri, 27 Jan 2012 17:53:44 +0100 5647512 http://www.medworm.com/index.php?rid=5647511&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F35wp1g56741026h6%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-4DOI 10.1007/s00392-012-0416-6Authors Alexander Jabs, 2nd Department of Medicine, Cardiology/Angiology/Intensive Care, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131 Mainz, GermanyUlrich Hink, 2nd Department of Medicine, Cardiology/Angiology/Intensive Care, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131 Mainz, GermanyAscan Warnholtz, 2nd Department of Medicine, Cardiology/Angiology/Intensive Care, University Medical Center of the Johannes Gutenberg-University Mainz, Langenbeckstr. 1, 55131 Mainz, GermanyRalph Stephan von Bardeleben, 2nd Department of Medicine, Cardiology/Angiology/Intensive Care, University Medical Center of the... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5647511 Fri, 27 Jan 2012 17:53:44 +0100 5647511 http://www.medworm.com/index.php?rid=5619898&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Flj141885l03445t7%2F Conclusion  The blockade of Her2/-neu receptors with trastuzumab in patients with breast cancer led to measurable alterations of left ventricular volume, left atrial volume, and systolic function as early as 3 months after start of treatment. Content Type Journal ArticleCategory Original PaperPages 1-12DOI 10.1007/s00392-011-0406-0Authors Stefan A. Lange, Medizinische Klinik I, Kardiologie und Angiologie, Klinikum Worms, Akademisches Lehrkrankenhaus der Johannes–Gutenberg–Universität, Mainz, GermanyBernd Ebner, Herzzentrum Dresden, Universitätsklinikum Carl-Gustav-Carus an der Technischen Universität, Dresden, GermanyAstrid Wess, Medizinische Klinik I, Kardiologie und Angiologie, Klinikum Worms, Akademisches Lehrkrankenhaus der Johannes–Gutenberg–Unive... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5619898 Tue, 17 Jan 2012 07:17:08 +0100 5619898 http://www.medworm.com/index.php?rid=5597175&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F683471x8562p5g72%2F In conclusion, low-pressure treatment with DCB was similarly effective as high-pressure treatment justifying clinical trials in vessels which will benefit from inhibition of neointimal proliferation but may not tolerate high inflation pressure. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0408-yAuthors Bodo Cremers, Department of Internal Medicine III, University of Saarland, 66421 Homburg/Saar, GermanyBettina Kelsch, Department of Radiology, Charité Humboldt University, Berlin, GermanyYvonne P. Clever, Department of Internal Medicine III, University of Saarland, 66421 Homburg/Saar, GermanyNeil Hattangadi, Fort Lee, NJ 07024, USADirk Mahnkopf, IMTR GmbH, Institute of Medical Technology and Research, Rottmersleben, GermanyUlrich Speck, Departme... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5597175 Thu, 12 Jan 2012 06:42:39 +0100 5597175 http://www.medworm.com/index.php?rid=5597176&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff2kx3100m2447621%2F Conclusion  H/PF4 antibodies are not rare in patients undergoing angioplasty and stenting. However, these antibodies are not associated with the occurrence of HRPR. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0411-3Authors Thomas Gremmel, Department of Internal Medicine II, Medical University of Vienna, Vienna, AustriaKarin Frühwirth, Clinical Department for Blood Group Serology and Transfusion Medicine, Medical University of Vienna, Waehringer Guertel 18-20, 1090 Vienna, AustriaChristoph W. Kopp, Department of Internal Medicine II, Medical University of Vienna, Vienna, AustriaAlexandra Kaider, Core Unit for Medical Statistics and Informatics, Section of Clinical Biometrics, Medical University of Vienna, Vienna, AustriaSabine St... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5597176 Wed, 11 Jan 2012 06:56:58 +0100 5597176 http://www.medworm.com/index.php?rid=5597178&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw1426g72q7384861%2F Conclusion  Our findings demonstrate that HMGB1 plasma concentration is elevated in HF and correlates with disease severity and that is an independent predictor of the combined endpoint death and heart transplantation in HF patients. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-011-0409-xAuthors H. C. Volz, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyD. Laohachewin, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyD. Schellberg, Department of Internal Medicine II, University of Heidelberg, Heidelberg, GermanyA. R. Wienbrandt, Department of Internal Medicine III, University of Heidelberg, Im Neuenheimer F... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5597178 Tue, 10 Jan 2012 06:41:00 +0100 5597178 http://www.medworm.com/index.php?rid=5597177&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe335867t217mw919%2F Abstract  The preferred use of dual-coil implantable defibrillator lead systems in current implantable defibrillator therapy is likely based on data showing statistically lower defibrillation thresholds with dual-coil defibrillator lead systems. The following review will summarize the clinical data for dual- versus single-coil defibrillator leads in the left and right pectoral implant locations, and will then discuss the clinical implications of single- versus dual-coil usage for atrial defibrillation, venous complications, and the risks associated with lead extraction. It will be noted that there are no comparative clinical studies on the use and outcomes of single- versus dual-coil lead systems in implantable defibrillator therapy over a long-term follow-up. The limited l... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5597177 Tue, 10 Jan 2012 06:41:00 +0100 5597177 http://www.medworm.com/index.php?rid=5597179&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm18x1910h1520252%2F Conclusion  In daily clinical practice, combining ivabradine with beta-blocker not only reduces heart rate, number of angina attacks, and nitrate consumption, but also improves the quality of life in patients with stable angina pectoris. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-011-0402-4Authors Karl Werdan, Department of Medicine III, University Hospital Halle (Saale) of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 06097 Halle (Saale), GermanyHenning Ebelt, Department of Medicine III, University Hospital Halle (Saale) of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Straße 40, 06097 Halle (Saale), GermanySebastian Nuding, Department of Medicine III, University Hospital Halle (Saale) of the ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5597179 Tue, 10 Jan 2012 06:40:58 +0100 5597179 http://www.medworm.com/index.php?rid=5581311&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F16557535gt15p682%2F Conclusions  Gender-related disparity in outcome still remains present after surgery with minimized extracorporeal circulation. However, female gender per se is not an independent risk factor for in-hospital mortality, but close attention should be paid on modifiable risk factors. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0410-4Authors Michael Ried, Department of Cardiothoracic Surgery, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, GermanyDirk Lunz, Department of Anesthesiology, University Medical Center Regensburg, Franz-Josef-Strauß-Allee 11, 93053 Regensburg, GermanyReinhard Kobuch, Department of Cardiothoracic Surgery, University Medical Center Regensburg, Franz-Josef-Strauß-Allee ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5581311 Sun, 08 Jan 2012 06:34:06 +0100 5581311 http://www.medworm.com/index.php?rid=5581312&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frqq82234r4440128%2F Conclusion  LA remodeling and dysfunction that accompany OSA can be detected in the subclinical stage with a detailed evaluation of active and passive functions of the LA using the 2D-STE method. Content Type Journal ArticleCategory Original PaperPages 1-11DOI 10.1007/s00392-011-0404-2Authors Refik Emre Altekin, Department of Cardiology, Faculty of Medicine, Akdeniz University, Dumlupinar Bouleward, Konyaalti, 07070 Antalya, TurkeyAtakan Yanikoglu, Department of Cardiology, Faculty of Medicine, Akdeniz University, Dumlupinar Bouleward, Konyaalti, 07070 Antalya, TurkeyMustafa Serkan Karakas, Department of Cardiology, Nigde State Hospital, Nigde, TurkeyDeniz Ozel, Department of Biostatistics and Medical Informatics, Faculty of Medicine, Akdeniz University, Antalya, Turk... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5581312 Fri, 06 Jan 2012 06:45:30 +0100 5581312 http://www.medworm.com/index.php?rid=5572068&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7083w26uk0g37856%2F Conclusion  The inflammatory response in patients with myocardial infarction complicated by cardiogenic shock, as reflected by the inflammatory markers IL-6, IL-7, IL-8 and IL-10, demonstrates a clinically relevant prognostic contribution to clinical outcome. Content Type Journal ArticleCategory Original PaperPages 1-10DOI 10.1007/s00392-011-0403-3Authors Roland Prondzinsky, Department of Medicine III, Martin-Luther-University Halle-Wittenberg, Halle/Saale, GermanySusanne Unverzagt, Institute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, Halle/Saale, GermanyHenning Lemm, Department of Medicine III, Martin-Luther-University Halle-Wittenberg, Halle/Saale, GermanyNikolas-Arne Wegener, Department of Medicine III, Martin... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5572068 Tue, 03 Jan 2012 06:43:47 +0100 5572068 http://www.medworm.com/index.php?rid=5572069&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F883h042v66g02054%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-3DOI 10.1007/s00392-011-0405-1Authors Tobias Härle, Department of Cardiology, Heart Center, Klinikum Oldenburg gGmbH, Rahel-Straus-Str. 10, 26133 Oldenburg, GermanyKay Kronberg, Department of Cardiology, Heart Center, Klinikum Oldenburg gGmbH, Rahel-Straus-Str. 10, 26133 Oldenburg, GermanyAlbrecht Elsässer, Department of Cardiology, Heart Center, Klinikum Oldenburg gGmbH, Rahel-Straus-Str. 10, 26133 Oldenburg, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5572069 Mon, 02 Jan 2012 16:54:11 +0100 5572069 http://www.medworm.com/index.php?rid=5572070&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpujn05h6ng459437%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-2DOI 10.1007/s00392-011-0401-5Authors Andreas Schuster, King’s College London British Heart Foundation (BHF) Centre of Excellence; National Institute of Health Research (NIHR) Biomedical Research Centre at Guy’s and St. Thomas’ NHS Foundation Trust; Wellcome Trust and Engineering and Physical Sciences Research Council (EPSRC) Medical Engineering Centre; Division of Imaging Sciences and Biomedical Engineering, The Rayne Institute, St. Thomas’ Hospital, London, SE1 7EH UKMasaki Ishida, King’s College London British Heart Foundation (BHF) Centre of Excellence; National Institute of Health Research (NIHR) Biomedical Research Centre at Guy’s and St. Thomas’ NHS Foundation Trust; Wellcome Trust and Engineering an... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5572070 Mon, 02 Jan 2012 16:54:09 +0100 5572070 http://www.medworm.com/index.php?rid=5552204&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9572412273710067%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-5DOI 10.1007/s00392-011-0396-yAuthors D. Basic, Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestr. 2-8, 61231 Bad Nauheim, GermanyH. Möllmann, Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestr. 2-8, 61231 Bad Nauheim, GermanyM. A. Haas, Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestr. 2-8, 61231 Bad Nauheim, GermanyA. Rolf, Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestr. 2-8, 61231 Bad Nauheim, GermanyA. Jovanovic, Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestr. 2-8, 61231 Bad Nauheim, GermanyChristoph Liebetrau, Department of Cardiology, Kerckhoff Heart and Thorax Center, Benekestr. 2-8, 61231 Bad Nauheim, G... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5552204 Mon, 26 Dec 2011 16:46:13 +0100 5552204 http://www.medworm.com/index.php?rid=5544355&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw3834146n8180548%2F Conclusions  ST-elevation in lead aVR is associated with a more severe course of APE, especially in patients with intermediate-risk. Therefore, aVR-ST-elevation might be useful in risk stratification of APE. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-011-0395-zAuthors Karin Janata, Department of Emergency Medicine, University of Medicine, Vienna, AustriaThomas Höchtl, 3rd Medical Department, Cardiology and Emergency Medicine, Wilhelminen Hospital, Montleartstrasse 37, 1160 Vienna, AustriaCatharina Wenzel, 1st Department of Internal Medicine, Oncology, University of Medicine, Vienna, AustriaRudolf Jarai, 3rd Medical Department, Cardiology and Emergency Medicine, Wilhelminen Hospital, Montleartstrasse 37, 1160 Vienna, AustriaBarbara ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5544355 Thu, 22 Dec 2011 06:44:04 +0100 5544355 http://www.medworm.com/index.php?rid=5544357&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F557867v0925xu718%2F Abstract Background  Novel cardioprotective strategies are required to improve clinical outcomes in high risk patients undergoing coronary artery bypass graft (CABG) ± valve surgery. Remote ischemic preconditioning (RIC), in which brief episodes of non-lethal ischemia and reperfusion are applied to the arm or leg, has been demonstrated to reduce perioperative myocardial injury following CABG ± valve surgery. Whether RIC can improve clinical outcomes in this setting is unknown and is investigated in the effect of remote ischemic preconditioning on clinical outcomes (ERICCA) trial in patients undergoing CABG surgery. (ClinicalTrials.gov Identifier: NCT01247545). Methods  The ERICCA trial is a multicentre randomized double-blinded contr... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5544357 Wed, 21 Dec 2011 20:13:37 +0100 5544357 http://www.medworm.com/index.php?rid=5544356&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd83605k372081857%2F Conclusions  Early inhibition of the platelet ADP-receptor with a high loading dose of 600 mg clopidogrel given in the prehospital phase in patients with STEMI scheduled for primary PCI is safe, did not increase pre-PCI patency of the infarct vessel, but was associated with a trend towards a reduction in clinical events. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0393-1Authors Uwe Zeymer, Klinikum Ludwigshafen, Medizinische Klinik B, Ludwigshafen, GermanyHans-Richard Arntz, Medizinische Klinik II, Charité Campus Benjamin Franklin, Berlin, GermanyBernd Mark, Klinikum Ludwigshafen, Medizinische Klinik B, Ludwigshafen, GermanyStephan Fichtlscherer, Universitätsklinikum, Frankfurt/Main, GermanyGerald Werner, Klinikum Darmsta... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5544356 Wed, 21 Dec 2011 20:13:37 +0100 5544356 http://www.medworm.com/index.php?rid=5524381&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe625208560573v16%2F Conclusions  Late occurrence of bradyarrhythmias should be recognized as a significant contributor to postprocedural outcome after TAVI. Although this is a well known phenomenon after surgical valve replacement, it is less recognized after TAVI. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0398-9Authors Emmanuel Chorianopoulos, Department of Cardiology, Angiology and Pulmonology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyUlrike Krumsdorf, Department of Cardiology, Angiology and Pulmonology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanySven T. Pleger, Department of Cardiology, Angiology and Pulmonology, Heidelberg University Hospital, Im Neuenheimer Feld 4... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5524381 Sat, 17 Dec 2011 17:04:10 +0100 5524381 http://www.medworm.com/index.php?rid=5515265&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F218854g340733k3l%2F Conclusion  Cardiac conduction disturbances were common in the early experience with CoreValve implantation necessitating close surveillance for at least 1 week. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0400-6Authors I. Akin, Heart Center Rostock, Department of Internal Medicine I, Rostock School of Medicine, University Hospital Rostock, Ernst-Heydemann-Str. 6, 18057 Rostock, GermanyS. Kische, Heart Center Rostock, Department of Internal Medicine I, Rostock School of Medicine, University Hospital Rostock, Ernst-Heydemann-Str. 6, 18057 Rostock, GermanyH. Schneider, Heart Center Rostock, Department of Internal Medicine I, Rostock School of Medicine, University Hospital Rostock, Ernst-Heydemann-Str. 6, 18057 Rostock, Germany... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5515265 Fri, 16 Dec 2011 16:56:31 +0100 5515265 http://www.medworm.com/index.php?rid=5515266&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0350275846121742%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-3DOI 10.1007/s00392-011-0399-8Authors Sebastian Kohl, Medical University Innsbruck, Innsbruck, AustriaOtmar Pachinger, Medical University Innsbruck, Innsbruck, AustriaBernhard Metzler, Medical University Innsbruck, Innsbruck, Austria Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5515266 Thu, 15 Dec 2011 16:50:23 +0100 5515266 http://www.medworm.com/index.php?rid=5494791&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft7838365ph237w7g%2F Conclusion  Our findings strongly implicate the functional miRNAs polymorphisms of hsa-mir-196a2 and hsa-mir-499 genes may modulate the occurrence or prognosis in Chinese CAD. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0391-3Authors Hong Zhi, Department of Cardiology, ZhongDa Hospital, Southeast University, Nanjing, ChinaLina Wang, Department of Epidemiology and Biostatistics, Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, 87 Ding Jiaqiao Rd, Nanjing, 210009 ChinaGenshan Ma, Department of Cardiology, ZhongDa Hospital, Southeast University, Nanjing, ChinaXingzhou Ye, Department of Cardiology, ZhongDa Hospital, Southeast University, Nanjing, ChinaXiaojin Y... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5494791 Sat, 10 Dec 2011 16:55:55 +0100 5494791 http://www.medworm.com/index.php?rid=5494792&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj0t1j5r361n10462%2F Conclusion  The results of our study revealed a significant inverse relationship between serum MMP-9 as a biomarker of early remodeling and the level of 25(OH) D in patients after an acute myocardial infarction. Moreover, low level of vitamin D was associated with patients’ mortality in this study. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0394-0Authors Hossein Khalili, Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box 14155/6451, 1417614411 Tehran, IranAzita Hajhossein Talasaz, Department of Clinical Pharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, P.O.Box 14155/6451, 1417614411 Tehran, IranMojtaba Salarifar, Department of Cardiology, Tehran Heart Cente... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5494792 Sat, 10 Dec 2011 16:55:54 +0100 5494792 http://www.medworm.com/index.php?rid=5494793&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn13662rug2571058%2F Conclusion  In patients with paradoxical embolism, recurrent ischemic events are frequent despite medical therapy. These events are not limited to the early years after the index event; this long-term follow-up revealed a risk of occurrence over the entire follow-up. These patients have a sustained risk of recurrence, requiring lifetime protection, which should be considered in tailoring individual therapeutic strategies. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0392-2Authors Dieter Fischer, Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl Neuberg Str.1, 30625 Hannover, GermanyAjmal Gardiwal, Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl Neuberg Str.1, 30625 Hann... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5494793 Sat, 10 Dec 2011 06:42:01 +0100 5494793 http://www.medworm.com/index.php?rid=5494794&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2313r71w21686254%2F Conclusions  Concurrent BMS/DES stenting is associated with an increase in in-hospital but not long-term mortality. Further, there was a significant increase in recurrent myocardial infarction and TVR, but absolute differences were low. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0390-4Authors Alessandro Cuneo, Abteilung für Kardiologie, Asklepios Klinik St-Georg, Hamburg, GermanyPeter Bramlage, Institut für Pharmakologie und präventive Medizin, Mahlow, GermanyMatthias Hochadel, Stiftung Institut für Herzinfarktforschung Ludwigshafen an der Universität Heidelberg, Ludwigshafen, GermanyJochen Senges, Stiftung Institut für Herzinfarktforschung Ludwigshafen an der Universität Heidelberg, Ludwigshafen, GermanyChristoph Nienabe... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5494794 Thu, 08 Dec 2011 18:24:06 +0100 5494794 http://www.medworm.com/index.php?rid=5486646&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F638038325q63466k%2F Conclusions  Cardiac involvement is a frequent finding in patients with mitochondrial myopathy. A potentially characteristic pattern of diffuse intramural LGE in the LV inferolateral segments was identified in patients suffering from the subforms CPEO or KSS. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0387-zAuthors Ali Yilmaz, Division of Cardiology, Robert-Bosch-Krankenhaus, Auerbachstrasse 110, 70376 Stuttgart, GermanyHans-Jürgen Gdynia, Department of Neurology, University of Ulm, Ulm, GermanyMatthias Ponfick, Department of Neurology, University of Ulm, Ulm, GermanySabine Rösch, Division of Cardiology, Robert-Bosch-Krankenhaus, Auerbachstrasse 110, 70376 Stuttgart, GermanyAlfred Lindner, Department of Neurology, Marienhospit... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5486646 Mon, 05 Dec 2011 17:43:38 +0100 5486646 http://www.medworm.com/index.php?rid=5476321&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft84736w4w12g4404%2F Conclusions  Tissue motion annular displacement is a rapid, sensitive and reproducible method for the assessment of LV longitudinal function, which is less dependent on image quality. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0389-xAuthors Sebastian J. Buss, Department of Cardiology, Angiology and Pneumology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDerliz Mereles, Department of Cardiology, University of Heidelberg, INF 410, 69120 Heidelberg, GermanyMostafa Emami, Department of Cardiology, University of Heidelberg, INF 410, 69120 Heidelberg, GermanyGrigorios Korosoglou, Department of Cardiology, University of Heidelberg, INF 410, 69120 Heidelberg, GermanyJohannes H. Riffel, Department of Cardi... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5476321 Sat, 03 Dec 2011 16:49:51 +0100 5476321 http://www.medworm.com/index.php?rid=5476322&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0209481l075hj808%2F Conclusions  This large pooled analysis showed that a high level of guideline adherence is achievable in the context of clinical studies. Those receiving and tolerating optimal pharmacotherapy experience a better prognosis. Nevertheless, the implementation of heart failure medication needs further improvement in female and elderly patients, especially those in NYHA functional class >II and patients with LVEF ≥30%. Content Type Journal ArticleCategory Original PaperPages 1-10DOI 10.1007/s00392-011-0388-yAuthors C. Zugck, Department of Cardiology, Angiology, Pulmonology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyJ. Franke, Department of Cardiology, Angiology, Pulmonology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 H... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5476322 Fri, 02 Dec 2011 17:28:21 +0100 5476322 http://www.medworm.com/index.php?rid=5449679&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk675u2j322q14814%2F Conclusion  Our study demonstrated that serum-soluble LOX-1 levels were associated with proximal/mid segment of the LAD lesions. Furthermore, this study suggested soluble LOX-1 might be a useful biomarker of coronary plaque vulnerability in patients with stable CAD. Soluble LOX-1, the novel biochemical marker, may provide new insights into not only risk stratification but also therapeutic strategy for CAD. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0386-0Authors Mehmet Balın, Department of Cardiology, Elazig Education and Research Hospital, Elazig, TurkeyAhmet Celik, Department of Cardiology, Elazig Education and Research Hospital, Elazig, TurkeyM. Ali Kobat, Department of Cardiology, Elazig Education and Research Hospital, E... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5449679 Thu, 24 Nov 2011 17:49:50 +0100 5449679 http://www.medworm.com/index.php?rid=5440586&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F66018240m1m6n832%2F Conclusion  Adverse early remodeling processes (reflected by LV dilatation between infarction and 4 months) determine long-term diastolic function in patients after reperfused AMI and progenitor cell therapy. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0382-4Authors Ulrich Fischer-Rasokat, Division of Cardiology, Department of Medicine III, Goethe University of Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, GermanyJörg Honold, Division of Cardiology, Department of Medicine III, Goethe University of Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, GermanyFlorian H. Seeger, Division of Cardiology, Department of Medicine III, Goethe University of Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt, GermanyStephan Fichtlscherer, ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5440586 Mon, 21 Nov 2011 18:06:31 +0100 5440586 http://www.medworm.com/index.php?rid=5440587&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc20187qw54723pq5%2F Conclusions  Markers of oxidative stress showed a significant up-regulation during the first 2 days after AF ablation. Their up-regulation was linked to inflammation, delivered radiofrequency energy, and early recurrence of AF, but did not predict long-term ablation outcome. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-011-0383-3Authors Bernhard Richter, Department of Cardiology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, AustriaMarianne Gwechenberger, Department of Cardiology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, AustriaAriel Socas, Department of Cardiology, Medical University of Vienna, Währinger Gürtel 18-20, 1090 Vienna, AustriaGerlinde Zorn, Department of Cardiolog... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5440587 Sat, 19 Nov 2011 06:50:47 +0100 5440587 http://www.medworm.com/index.php?rid=5431572&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv82853l127306165%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-3DOI 10.1007/s00392-011-0384-2Authors L. Paranskaya, Department of Cardiology, University Hospital of Rostock, E-Heydemann-Str. 6, 18057 Rostock, GermanyI. Turan, Department of Cardiology, University Hospital of Rostock, E-Heydemann-Str. 6, 18057 Rostock, GermanyS. Kische, Department of Cardiology, University Hospital of Rostock, E-Heydemann-Str. 6, 18057 Rostock, GermanyC. Nienaber, Department of Cardiology, University Hospital of Rostock, E-Heydemann-Str. 6, 18057 Rostock, GermanyH. Ince, Department of Cardiology, University Hospital of Rostock, E-Heydemann-Str. 6, 18057 Rostock, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5431572 Fri, 18 Nov 2011 17:28:34 +0100 5431572 http://www.medworm.com/index.php?rid=5431573&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F13321rm5p5429170%2F Conclusions  Altered systemic venous flow return is associated with suboptimal Fontan hemodynamics and seems to progress with patients’ age and long-term follow-up after Fontan operation. Thus, MRI flow volume measurements might help in monitoring Fontan patients before the onset of clinical signs of suboptimal hemodynamics. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00392-011-0374-4Authors S. Ovroutski, Department of Congenital Heart Diseases, Deutsches Herzzentrum Berlin (German Heart Institute Berlin), Augustenburger Platz 1, 13533 Berlin, GermanyS. Nordmeyer, Department of Congenital Heart Diseases, Deutsches Herzzentrum Berlin (German Heart Institute Berlin), Augustenburger Platz 1, 13533 Berlin, GermanyO. Miera, Department of Con... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5431573 Fri, 18 Nov 2011 06:59:41 +0100 5431573 http://www.medworm.com/index.php?rid=5407572&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F37n3583573x16624%2F Conclusion  Data collected in DES.DE revealed that first generation DES used in SVG lesions did not offset the worse clinical outcomes of bypass-graft intervention. Such sobering results in SVG may suggest to opt for native vessel PCI preferentially or occasionally for surgical reintervention as decided by the Heart Team. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0381-5Authors Ibrahim Akin, Divisions of Cardiology, Pulmology and Intensive Care Medicine, Department of Internal Medicine I, Heart Center Rostock, University Hospital Rostock, Rostock School of Medicine, Ernst-Heydemann-Str. 6, 18057 Rostock, GermanyMarcus Wiemer, Department of Cardiology, Heart Center Bad Oeynhausen, Bad Oeynhausen, GermanySteffen Schneider, Depart... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5407572 Sat, 12 Nov 2011 16:54:17 +0100 5407572 http://www.medworm.com/index.php?rid=5407573&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp05268l2t4146341%2F In conclusion, in STEMI patients reperfused by primary PCI, time-to-reperfusion was an independent predictor for transmural infarction but not for infarct size and MO. However, transmural infarction was not predictive of death and congestive heart failure. Content Type Journal ArticleCategory Original PaperPages 1-10DOI 10.1007/s00392-011-0380-6Authors Suzanne de Waha, Department of Internal Medicine/Cardiology, University of Leipzig-Heart Center, Strümpellstr. 39, 04289 Leipzig, GermanyIngo Eitel, Department of Internal Medicine/Cardiology, University of Leipzig-Heart Center, Strümpellstr. 39, 04289 Leipzig, GermanySteffen Desch, Department of Internal Medicine/Cardiology, University of Leipzig-Heart Center, Strümpellstr. 39, 04289 Leipzig, GermanyGeorg Fuernau, Department of ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5407573 Wed, 09 Nov 2011 17:56:49 +0100 5407573 http://www.medworm.com/index.php?rid=5407574&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9643k437k160x115%2F Conclusion  A standard clinical SSFP sequence is not inferior to T2-BB-TSE for the detection of myocardial oedema and can be used to reliably distinguish AMI from CMI. Especially in patients with insufficient T2-BB-TSE image quality, the SSFP sequence may be an alternative for the detection of myocardial oedema. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0373-5Authors Henning Steen, Department of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyFrederik Voss, Department of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyFlorian André, Department of Cardiology, University Hospital Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Ger... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5407574 Tue, 08 Nov 2011 19:16:00 +0100 5407574 http://www.medworm.com/index.php?rid=5386029&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb23747827458v310%2F Conclusion  It is possible to identify STEMIs by cECG. This innovative technique could play an important role in the pre-hospital period as well as in the hospital. Content Type Journal ArticleCategory Original PaperPages 1-10DOI 10.1007/s00392-011-0377-1Authors Mareike B. Weil, Department of Cardiology and Pneumology/Heart Center, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, GermanyMartin Oehler, Institute of Electrical Measurement Science and Fundamental Electrical Engineering, TU Braunschweig, GermanyMeinhard Schilling, Institute of Electrical Measurement Science and Fundamental Electrical Engineering, TU Braunschweig, GermanyLars S. Maier, Department of Cardiology and Pneumology/Heart Center, Georg-August-University Göttingen, Robert... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5386029 Mon, 07 Nov 2011 17:13:36 +0100 5386029 http://www.medworm.com/index.php?rid=5386030&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn21371g5681j8477%2F Conclusions  This study suggests that thiamine supplementation has beneficial effects on cardiac function in patients with diuretic drugs for symptomatic chronic heart failure. Subclinical thiamine deficiency is probably an underestimated issue in these outpatients. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00392-011-0376-2Authors Andreas W. Schoenenberger, Division of Geriatrics, Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, SwitzerlandRenate Schoenenberger-Berzins, Department of Cardiology, Luzerner Kantonsspital, 6000 Lucerne 16, SwitzerlandChristoph Auf der Maur, Department of Cardiology, Luzerner Kantonsspital, 6000 Lucerne 16, SwitzerlandPaolo M. Suter, Clinic and Policlin... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5386030 Sat, 05 Nov 2011 15:43:16 +0100 5386030 http://www.medworm.com/index.php?rid=5386031&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F52v133p014672808%2F Conclusion  Repeat defibrillation testing after administration of amiodarone therapy rarely fails in patients with left-sided devices. We observed a higher test failure in patients with a device in the right-subpectoral position although this subgroup was small. Repeat defibrillator testing is safe as no relevant complications were observed. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00392-011-0379-zAuthors Julia Köbe, Division of Clinical and Experimental Electrophysiology, Department of Cardiology and Angiology, University Hospital of Münster, Münster, GermanyFlorian Reinke, Division of Clinical and Experimental Electrophysiology, Department of Cardiology and Angiology, University Hospital of Münster, Münster, GermanyDirk G. Deche... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5386031 Fri, 04 Nov 2011 16:50:36 +0100 5386031 http://www.medworm.com/index.php?rid=5386032&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F21n2424k372x3q17%2F Conclusions  A heart rate ≥90 bpm at the time of MODS diagnosis is an independent risk factor for increased 28-day mortality. As in patients with cardiovascular conditions such as coronary heart disease or chronic heart failure, heart rate might constitute a target for heart rate-lowering therapy in the narrow initial treatment window of MODS. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-011-0375-3Authors Robert S. Hoke, Department of Medicine, Halle (Saale) University Hospital, Ernst-Grube-Str. 40, 06097 Halle (Saale), GermanyUrsula Müller-Werdan, Department of Medicine, Halle (Saale) University Hospital, Ernst-Grube-Str. 40, 06097 Halle (Saale), GermanyChristine Lautenschläger, Institute for Medical Epidemiology, Biometric... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5386032 Wed, 02 Nov 2011 17:00:01 +0100 5386032 http://www.medworm.com/index.php?rid=5386033&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F94t4n11809210550%2F Conclusions  Our results demonstrate a tendency towards a reduction of mechanical ventilation time for patients without severe illness after sudden cardiac arrest achieved by implementation of a new sedation management, whereby significant longer ventilation time was observed for severe ill patients. Because of lack of statistical significance of our present study, a randomized study with sufficient power is necessary to demonstrate positive effects of a standardized sedation management and its influence on severity of illness. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-011-0378-0Authors Nadine Abanador-Kamper, Department of Cardiology, Helios Medical Centre Wuppertal, Witten/Herdecke University, Wuppertal, GermanyLars Kamper, De... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5386033 Wed, 02 Nov 2011 17:00:00 +0100 5386033 http://www.medworm.com/index.php?rid=5347163&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe36vmwnx4729107w%2F Conclusions  Acutely, direct intracoronary bolus injection resulted in a more pronounced local inhibition of platelet function and a higher degree of GP IIb/IIIa receptor occupancy as compared to standard intravenous bolus injection. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0372-6Authors Steffen Desch, Department of Internal Medicine/Cardiology, Heart Center, University of Leipzig, Strümpellstr. 39, 04289 Leipzig, GermanyAnnelie Siegemund, MVZ Labor Dr. Reising-Ackermann und Kollegen, Leipzig, GermanyUte Scholz, MVZ Labor Dr. Reising-Ackermann und Kollegen, Leipzig, GermanyNatalie Adam, MVZ Labor Dr. Reising-Ackermann und Kollegen, Leipzig, GermanyIngo Eitel, Department of Internal Medicine/Cardiology, Heart Center, Universit... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5347163 Fri, 21 Oct 2011 05:48:11 +0100 5347163 http://www.medworm.com/index.php?rid=5347164&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu308983526x04288%2F Conclusion  We evaluated heart-focused anxiety in the general population and validated the CAQ. Using percentiles based on a normative sample allows screening for heart-focused anxiety in patients with or without cardiac diseases and the measurement of therapy success after psychotherapeutic or pharmacological intervention. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0371-7Authors Denise Fischer, Universitätsklinikum des Saarlandes, Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Kirrberger Straße, 66421 Homburg/Saar, GermanyIngrid Kindermann, Universitätsklinikum des Saarlandes, Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Kirrberger... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5347164 Thu, 20 Oct 2011 15:52:51 +0100 5347164 http://www.medworm.com/index.php?rid=5296821&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxj16751721213527%2F Conclusion  Body weight, patient activity, and the difference between MHR and RHR are mutually correlated and may reasonably contribute to an algorithm for predicting heart failure deterioration. Blood pressure appears to offer no additional value. As both genesis and symptoms of heart failure exacerbation are non-uniform and complex, the telemonitoring concepts for heart failure patients should employ continuous monitoring of multiple diagnostic parameters, rather than rely on a single parameter. Provided that patient compliance is strictly supervised, reliable data flow from sensors requiring patient involvement is possible. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0369-1Authors Ann Lieback, Department of Internal Medicin... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5296821 Wed, 05 Oct 2011 05:50:29 +0100 5296821 http://www.medworm.com/index.php?rid=5296822&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu5388v6h1771222w%2F Conclusions  In patients with severe AS undergoing AVR, mild-to-moderate PH is a strong and independent predictor of late mortality. Conversely, patients with normal PAPsys have an extremely good prognosis. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0367-3Authors Christine S. Zuern, Innere Medizin III, Kardiologie und Herz-/Kreislauferkrankungen, Eberhard-Karls-Universität Tübingen, Otfried-Müller-Str. 10, 72076 Tübingen, GermanyChristian Eick, Innere Medizin III, Kardiologie und Herz-/Kreislauferkrankungen, Eberhard-Karls-Universität Tübingen, Otfried-Müller-Str. 10, 72076 Tübingen, GermanyKonstantinos Rizas, Innere Medizin III, Kardiologie und Herz-/Kreislauferkrankungen, Eberhard-Karls-Universität Tübingen, Otfried-... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5296822 Tue, 04 Oct 2011 05:57:02 +0100 5296822 http://www.medworm.com/index.php?rid=5285365&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj887513072789681%2F This article provides information and commentaries on trials which were presented at the Hotline and Clinical Trial Update Sessions during the Late Breaking Clinical Trial Sessions European Society of Cardiology Congress, held in Paris, France, from 27th to 31st August 2011. This article gives an overview on a number of novel clinical trials in the field of cardiovascular medicine, which were presented. The data have been presented by leading experts in the accordant field with relevant positions in the trials. Unpublished reports should be considered as preliminary data as the analysis may change in the final publications. The comprehensive summaries have been generated from the oral presentation and the webcasts of the European Society of Cardiology, similar as previously reported ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5285365 Fri, 30 Sep 2011 05:53:41 +0100 5285365 http://www.medworm.com/index.php?rid=5285364&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3180208u3247m302%2F Conclusion  Our findings suggest that RDN is feasible even in cardiac unstable patients. Randomized controlled trials are urgently needed to study the effects of RD in patients with electrical storm and CHF. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00392-011-0365-5Authors Christian Ukena, Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Universitätsklinikum des Saarlandes, Kirrberger Str. 1, 66421 Homburg/Saar, GermanyAxel Bauer, Medizinische Klinik III, Eberhard Karls Universität, 72074 Tübingen, GermanyFelix Mahfoud, Klinik für Innere Medizin III (Kardiologie, Angiologie und Internistische Intensivmedizin), Universitätsklinikum des Saarlandes, Kirrberger Str. 1, 66421 Homburg/Saar, Germ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5285364 Fri, 30 Sep 2011 05:53:41 +0100 5285364 http://www.medworm.com/index.php?rid=5285366&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr243743418357826%2F Conclusions  TWA showed high negative predictive ability for lethal ventricular tachyarrhythmia in patients with LV dysfunction, although the TWA-negative patients accounted for only 18% of the entire population. Those ineligible for the TWA test had the highest risk for lethal ventricular tachyarrhythmia. Content Type Journal ArticleCategory Original PaperPages 1-11DOI 10.1007/s00392-011-0368-2Authors Satoshi Shizuta, Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shougoin, Sakyo-ku, Kyoto, 606-8507 JapanKenji Ando, Kokura Memorial Hospital, Kitakyushu, JapanMasakiyo Nobuyoshi, Kokura Memorial Hospital, Kitakyushu, JapanTakanori Ikeda, Kyorin University School of Medicine, Mitaka, JapanHideaki Yoshino, Kyorin Un... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5285366 Fri, 30 Sep 2011 05:53:40 +0100 5285366 http://www.medworm.com/index.php?rid=5285367&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh0233h73762x7t54%2F Abstract  Cardiac malformations with impact on loading patterns have the potential to progress to irreversible loss of ventricular function during human fetal life. N-terminal pro-B-type natriuretic peptide (nt-proBNP) is a marker of cardiac dysfunction and involved in cardiac remodeling and fibrosis. We evaluated nt-proBNP levels in the circulation of human fetuses with cardiac defects. A total of 45 cases and 75 controls during the second half of gestation were recruited. Nt-proBNP concentrations were determined in venous specimens obtained by fetal blood sampling. Results were correlated to echocardiography and Doppler studies. Mean gestational age was 26.9 weeks (range 21.0–33.4 weeks). Levels of circulating nt-proBNP were elevated in fetuses with cardiac de... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5285367 Fri, 30 Sep 2011 05:53:39 +0100 5285367 http://www.medworm.com/index.php?rid=5260424&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj500528114831103%2F Conclusion  In patients with successful recanalization of complex CTOs the use of EESs results in a low angiographic late loss and restenosis rate without stent thrombosis throughout 12 months follow-up. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00392-011-0359-3Authors Jochen Wöhrle, Department of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, GermanyWolfgang Rottbauer, Department of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, GermanyArmin Imhof, Department of Internal Medicine II, University of Ulm, Albert-Einstein-Allee 23, 89081 Ulm, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiol... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5260424 Thu, 22 Sep 2011 06:39:10 +0100 5260424 http://www.medworm.com/index.php?rid=5260426&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff56xp316064p0h26%2F Conclusion  A low pulse pressure is an independent predictor of mortality in subjects with depressed left ventricular ejection fraction after a recent myocardial infarction and evidence of Killip Class II–IV heart failure. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0360-xAuthors Colin J. Petrie, Clinical Research Initiative, Department of Cardiology, Western Infirmary, Glasgow, G11 6NT Scotland, UKAdriaan A. Voors, Department of Cardiology, Thoraxcenter, University Medical Center Groningen, PO Box 30001, 9700 RB Groningen, The NetherlandsMichele Robertson, Robertson Centre for Biostatistics, University of Glasgow, Glasgow, G11 6NT Scotland, UKDirk J. van Veldhuisen, Department of Cardiology, Thoraxcenter, University Medical Ce... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5260426 Wed, 21 Sep 2011 05:54:44 +0100 5260426 http://www.medworm.com/index.php?rid=5260425&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp732875651uxn831%2F Conclusions  Most adults with CHD are fairly active. Daily activity is positively correlated with exercise capacity. Therefore, promotion of an active lifestyle seems warranted after medical counseling. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0364-6Authors Jan Müller, Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum München, Technische Universität München, Lazarettstr. 36, 80636 Munich, GermanyJohn Hess, Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum München, Technische Universität München, Lazarettstr. 36, 80636 Munich, GermanyAlfred Hager, Department of Pediatric Cardiology and Congenital Heart Disease, Deutsches Herzzentrum München, Techn... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5260425 Wed, 21 Sep 2011 05:54:44 +0100 5260425 http://www.medworm.com/index.php?rid=5250555&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff467286w27m97332%2F Conclusion  Our study indicates that TAVI under LAPS is as effective and safe as TAVI under GA. Furthermore, total procedure time, intervention time and labor costs could be reduced by LAPS. Mobilization of patients could be achieved earlier. We therefore consider LAPS to be favorable in patients undergoing transfemoral TAVI. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00392-011-0362-8Authors Lukas J. Motloch, Department of Internal Medicine II, Paracelsus Medical University Salzburg, Muellner Hauptstr. 48, 5020 Salzburg, AustriaDennis Rottlaender, Department of Internal Medicine II, Paracelsus Medical University Salzburg, Muellner Hauptstr. 48, 5020 Salzburg, AustriaSara Reda, Department of Internal Medicine II, Paracelsus Medical Univer... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5250555 Mon, 19 Sep 2011 15:40:18 +0100 5250555 http://www.medworm.com/index.php?rid=5250556&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn564824t4308772g%2F Conclusion  Lower concentrations of Hb on admission are associated with higher rates of in-hospital mortality, heart failure and major bleeding after p-PCI. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00392-011-0361-9Authors Cihan Dündar, Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeyVecih Oduncu, Department of Cardiology, Kosuyolu Heart Education and Research Hospital, Istanbul, TurkeyAyhan Erkol, Department of Cardiology, Kocaeli Derince Education and Research Hospital, İbni Sina Bulvarı, 41900 Derince, Kocaeli, TurkeyAli Cevat Tanalp, Department of Cardiology, Medicana International Hospital, Ankara, TurkeyDicle Sırma, Department of Cardiology, Kosuyolu Heart Education and Research Hospita... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5250556 Mon, 19 Sep 2011 13:43:48 +0100 5250556 http://www.medworm.com/index.php?rid=5250557&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F664124r564g00j56%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-2DOI 10.1007/s00392-011-0363-7Authors Michele Correale, Department of Cardiology, “Ospedali Riuniti”OO.RR, University of Foggia, viale L Pinto, 1, 71100 Foggia, ItalyLuigi Di Martino, Department of Cardiology, “Ospedali Riuniti”OO.RR, University of Foggia, viale L Pinto, 1, 71100 Foggia, ItalyRiccardo Ieva, Department of Cardiology, “Ospedali Riuniti”OO.RR, University of Foggia, viale L Pinto, 1, 71100 Foggia, ItalyMatteo Di Biase, Department of Cardiology, “Ospedali Riuniti”OO.RR, University of Foggia, viale L Pinto, 1, 71100 Foggia, ItalyNatale Daniele Brunetti, Department of Cardiology, “Ospedali Riuniti”OO.RR, University of Foggia, viale L Pinto, 1, 71100 Foggia, Italy Journal Clinical Rese... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5250557 Mon, 19 Sep 2011 13:43:47 +0100 5250557 http://www.medworm.com/index.php?rid=5225186&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh2132xt605627327%2F Content Type Journal ArticleCategory Letter to the EditorsPages 1-5DOI 10.1007/s00392-011-0358-4Authors U. Krause, Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, GermanyV. Gravenhorst, Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, GermanyT. Kriebel, Department of Pediatric Cardiology and Intensive Care Medicine, University Hospital, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, GermanyW. Ruschewski, Department of Thoracic and Cardiovascular Surgery, Georg-August-University, Göttingen, GermanyT. Paul, Department of Pediatric Cardiolog... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5225186 Tue, 13 Sep 2011 15:44:41 +0100 5225186 http://www.medworm.com/index.php?rid=5225187&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff634807792q12325%2F Conclusions  Impaired renal function in patients undergoing DES stenting carries an independent risk factor for restenosis and bleeding. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0347-7Authors Elif Kaya, Department of Cardiology and Angiology, University Hospital of Münster, Albert-Schweitzer Strasse 33, 48149 Münster, GermanyAlessandro Cuneo, Medizinische Klinik II, Klinikum Lippe-Detmold, Detmold, GermanyMatthias Hochadel, Institut für Herzinfarktforschung Ludwigshafen an der Universität Heidelberg, Ludwigshafen, GermanyClaus Jünger, Institut für Herzinfarktforschung Ludwigshafen an der Universität Heidelberg, Ludwigshafen, GermanyWibke Stepper, Department of Cardiology and Angiology, University Hospital of Münster, Albe... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5225187 Mon, 12 Sep 2011 15:52:56 +0100 5225187 http://www.medworm.com/index.php?rid=5225188&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F07p0610u77004548%2F Conclusions  New onset AF in the AMI setting carries a substantial future risk for stroke and should not be regarded as a benign, transient complication of the acute event. Long term anticoagulation is underused and is associated with improved stroke-free survival. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00392-011-0357-5Authors Oren Zusman, Department of Cardiology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, IsraelGuy Amit, Department of Cardiology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, IsraelHarel Gilutz, Department of Cardiology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gu... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5225188 Sun, 11 Sep 2011 05:34:18 +0100 5225188 http://www.medworm.com/index.php?rid=5225189&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv83028m81537484v%2F Conclusion  The reported prevalences of severe CHD are within the range of regional and European comparative data. The prenatal detection rate of severe cardiovascular malformations is comparable to contemporary European registries. Postnatal diagnosis of the CHD has been made early in life. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00392-011-0355-7Authors Gerda Schwedler, Deutsches Herzzentrum Berlin—Kompetenznetz Angeborene Herzfehler, Augustenburger Platz 1, 13353 Berlin, GermanyAngelika Lindinger, Klinik fürPädiatrische Kardiologie, Universitätsklinikum des Saarlandes, 66421 Homburg/Saar, GermanyPeter E. Lange, Deutsches Herzzentrum Berlin—Kompetenznetz Angeborene Herzfehler, Augustenburger Platz 1, 13353 Berlin, GermanyUlric... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5225189 Sat, 10 Sep 2011 06:04:05 +0100 5225189 http://www.medworm.com/index.php?rid=5208332&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmn74686808331g12%2F Conclusion  A family history of premature cardiovascular disease and male gender were found to have strong, independent associations with having a snow-shoveling-related ACS. A history of chronic stable angina trended toward an association. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00392-011-0356-6Authors Robert B. Nichols, Cardiac Electrophysiology and Pacing, Division of Cardiology, Kingston General Hospital, Queen’s University, Kingston, ON K7L 2V7, CanadaWilliam F. McIntyre, Cardiac Electrophysiology and Pacing, Division of Cardiology, Kingston General Hospital, Queen’s University, Kingston, ON K7L 2V7, CanadaSalina Chan, Cardiac Electrophysiology and Pacing, Division of Cardiology, Kingston General Hospital, Queen’s University... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5208332 Fri, 09 Sep 2011 05:59:07 +0100 5208332 http://www.medworm.com/index.php?rid=5131914&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0320ht11028n3626%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00392-011-0354-8Authors Antoinette de Waha, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyAlban Dibra, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanySebastian Kufner, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyDietrich Baumgart, Preventicum-Klinik für Diagnostik, Essen, GermanyManel Sabate, Cardiovascular Institute, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainAleardo Maresta, Division of Cardiology, Interventional Center, S. Maria delle Croci Hospital, Ravenna, ItalyAlbert Schömig, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyAdnan Kastrati, Deutsches Herzzentrum,... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5131914 Fri, 12 Aug 2011 06:14:44 +0100 5131914 http://www.medworm.com/index.php?rid=5109211&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl7317224494vn51t%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00392-011-0353-9Authors Roman Pfister, Medizinische Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50924 Cologne, GermanyKonrad F. Frank, Medizinische Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50924 Cologne, GermanyStephan Rosenkranz, Medizinische Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50924 Cologne, GermanyGuido Michels, Medizinische Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50924 Cologne, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5109211 Sat, 06 Aug 2011 05:53:16 +0100 5109211 http://www.medworm.com/index.php?rid=5109210&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5h445115062u211w%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-011-0352-xAuthors Gjin Ndrepepa, Deutsches Herzzentrum, Klinik für Herz- und Kreislauferkrankungen, Lazarettstrasse 36, 80636 Munich, GermanyAlbert Schömig, Deutsches Herzzentrum, Klinik für Herz- und Kreislauferkrankungen, Lazarettstrasse 36, 80636 Munich, GermanyAdnan Kastrati, Deutsches Herzzentrum, Klinik für Herz- und Kreislauferkrankungen, Lazarettstrasse 36, 80636 Munich, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5109210 Sat, 06 Aug 2011 05:53:16 +0100 5109210 http://www.medworm.com/index.php?rid=5088085&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg51t4tv281641856%2F Conclusions  In a swine model, renal denervation via the Symplicity Catheter System resulted in no clinically significant adverse renal artery or renal findings 6 months after the procedure. This is corroborated by the vascular safety profile demonstrated in subsequent human clinical studies. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0346-8Authors Marian K. Rippy, Rippy Pathology Solutions, Woodbury, MN, USADenise Zarins, Medtronic Ardian, Mountain View, CA, USANeil C. Barman, Medtronic Ardian, Mountain View, CA, USAAndrew Wu, Medtronic Ardian, Mountain View, CA, USAKeith L. Duncan, Peninsula Pathology Medical Group, South San Francisco, CA, USAChristopher K. Zarins, Stanford University, Stanford, CA, USA Journal Clinical Research in Car... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5088085 Wed, 27 Jul 2011 15:50:40 +0100 5088085 http://www.medworm.com/index.php?rid=5088087&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmt25364w7225818x%2F Conclusion  hsTnT at the 99th percentile cutoff is useful for the diagnostic evaluation of patients with ACS, and provides strong and independent predictive power for adverse long-term outcomes even after early invasive strategy. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0344-xAuthors S. Celik, Medizinische Klinik, Abteilung für Innere Medizin III, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyE. Giannitsis, Medizinische Klinik, Abteilung für Innere Medizin III, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyK. C. Wollert, Klinik für Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, GermanyK. Schwöbel, Medizinische Klinik, A... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5088087 Tue, 26 Jul 2011 15:49:15 +0100 5088087 http://www.medworm.com/index.php?rid=5088086&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fwr885165680011w4%2F Conclusion  This study demonstrates the marked disparity between the patient cohorts with chronic systolic heart failure presenting at secondary and tertiary hospitals. Though patient characteristics—particularly age, aetiology of heart failure and the time of implementation of pharmacological and device treatment of heart failure—differed significantly, after adjustment for differences in baseline characteristics, no substantial difference in the combined endpoint of all-cause mortality and HTX was found during the 5-year follow-up period. Content Type Journal ArticlePages 1-10DOI 10.1007/s00392-011-0348-6Authors Jennifer Franke, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyChristian Zugck, Department of... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5088086 Tue, 26 Jul 2011 15:49:15 +0100 5088086 http://www.medworm.com/index.php?rid=5070129&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg12221011g72j015%2F Abstract  Two sons of a consanguineous marriage developed biventricular cardiomyopathy. One boy died of severe heart failure at the age of 6 years, the other was transplanted because of severe heart failure at the age of 10 years. In addition, focal palmoplantar keratoderma and woolly hair were apparent in both boys. As similar phenotypes have been described in Naxos disease and Carvajal syndrome, respectively, the genes for plakoglobin (JUP) and desmoplakin (DSP) were screened for mutations using direct genomic sequencing. A novel homozygous 2 bp deletion was identified in an alternatively spliced region of DSP. The deletion 5208_5209delAG led to a frameshift downstream of amino acid 1,736 with a premature truncation of the predominant cardiac isoform DSP-1. ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5070129 Mon, 25 Jul 2011 15:45:25 +0100 5070129 http://www.medworm.com/index.php?rid=5063521&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdv6745434x076v14%2F Conclusion  To date, this is the largest analysis of serial NT-proBNP measurements in patients with CHF receiving individually optimized medical therapy. These data suggest that a single NT-proBNP measurement after 6 months in stable clinical conditions may have higher predictive value than stratification of change in serial measurements. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0340-1Authors Jennifer Franke, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyLutz Frankenstein, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyDieter Schellberg, Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Ger... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5063521 Thu, 21 Jul 2011 18:13:09 +0100 5063521 http://www.medworm.com/index.php?rid=5063522&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl86x578413rlu371%2F Abstract  Heart failure is a frequent and life-threatening syndrome which is not only the result of myocardial injury or hemodynamic overload as commonly perceived, but appears to be the result of an interplay among genetic, neurohormonal, inflammatory, and biochemical factors, collectively referred to as biomarkers. Biomarkers can become risk factors in case their therapeutic modification results in an improvement of clinical outcomes. Among those markers identified in patients with heart failure, a number appears to have direct clinical relevance in aiding diagnosis, risk stratification, monitoring therapy, and treating to targets in order to improve clinical outcomes. These include brain natriuretic peptides (e.g., BNP, NT-proBNP), inflammatory markers (e.g., hsCRP), neu... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5063522 Thu, 21 Jul 2011 18:13:06 +0100 5063522 http://www.medworm.com/index.php?rid=5039171&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft55266n27m338711%2F Conclusions  Copeptin has a distinct release pattern in patients with ST-elevation AMI, peaking within the first hour after symptom onset before conventional cardiac biomarkers and falling to normal ranges within the first day. Further studies are required to determine the exact role of copeptin in AMI suspects presenting within the first hours after symptom onset. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0343-yAuthors Youlan L. Gu, Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB Groningen, The NetherlandsAdriaan A. Voors, Department of Cardiology, Thorax Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, PO Box 30001, 9700 RB... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5039171 Fri, 15 Jul 2011 15:59:17 +0100 5039171 http://www.medworm.com/index.php?rid=5020369&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3142427472446t36%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-011-0342-zAuthors Edlira Maska, Department of Medicine, University of Florida College of Medicine, Gainesville, FL, USASteven M. Dorman, Department of Medicine, University of Texas Southwestern Medical School, Dallas, TX, USARichard S. Schofield, Division of Cardiovascular Medicine, University of Florida College of Medicine, Gainesville, FL, USA Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5020369 Sat, 09 Jul 2011 06:23:51 +0100 5020369 http://www.medworm.com/index.php?rid=5009802&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc2314h765r4g8l63%2F A ticking time bomb? A case report of very late stent thrombosis more than 2 years after fracture of a Cypher stent Content Type Journal ArticlePages 1-3DOI 10.1007/s00392-011-0339-7Authors Sea Hing Ong, Department of Cardiology/Angiology, HELIOS Klinikum Siegburg, Medizinische Klinik-Kardiologie, Ringstrasse 49, 53721 Siegburg, GermanyRalf Mueller, Department of Cardiology/Angiology, HELIOS Klinikum Siegburg, Medizinische Klinik-Kardiologie, Ringstrasse 49, 53721 Siegburg, GermanyPeter Boekstegers, Department of Cardiology/Angiology, HELIOS Klinikum Siegburg, Medizinische Klinik-Kardiologie, Ringstrasse 49, 53721 Siegburg, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5009802 Sat, 02 Jul 2011 21:32:30 +0100 5009802 http://www.medworm.com/index.php?rid=5009803&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fuj8100120l1604n3%2F Conclusion  In this cohort of AF patients, old age, elevated sVCAM-1 and MMP-2 levels were associated with cardiovascular events. Our data indicate that single-time biomarker assessment may be a useful tool to improve risk stratification schemes. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0337-9Authors Joachim R. Ehrlich, Division of Cardiology, Section of Electrophysiology, Goethe-University, Theodor Stern Kai 7, 60590 Frankfurt, GermanyMagdalena Kaluzny, Division of Cardiology, Section of Electrophysiology, Goethe-University, Theodor Stern Kai 7, 60590 Frankfurt, GermanyStefan Baumann, Division of Cardiology, Section of Electrophysiology, Goethe-University, Theodor Stern Kai 7, 60590 Frankfurt, GermanyRalf Lehmann, Division of Cardiology, Section of... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=5009803 Sat, 02 Jul 2011 21:32:29 +0100 5009803 http://www.medworm.com/index.php?rid=4998584&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7041r220m1150q10%2F Conclusions  Both non-invasive techniques are associated with low operating costs and require only a few expendable items for the rapid determination of cardiac function. We found an acceptable agreement between IGR and ICG as well as a high reproducibility, which was statistically significant higher for ICG. For cardiac output states exceeding the physiological range, we found a statistically significant difference. Consequently, values of cardiac function determined by either method should not be used interchangeably in the clinical setting. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0329-9Authors Frederik Trinkmann, First Department of Medicine (Cardiology, Angiology, Pneumology, Intensive Care), Universitätsmedizin Mannheim, University of Heid... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4998584 Thu, 30 Jun 2011 17:49:17 +0100 4998584 http://www.medworm.com/index.php?rid=4993637&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3n8pw72gw0562197%2F Abstract  Primary percutaneous coronary intervention (PPCI) is superior to thrombolysis (TL) as reperfusion therapy in ST-elevation myocardial infarction (STEMI). TL is a rapidly available, but semi-effective therapy (effective reperfusion in 50% of patients only), whereas PPCI is a potentially delayed, but highly effective therapy (effective reperfusion in >90%). Since TL loses its efficacy beyond 2–3 h after symptom onset, it is a significant reperfusion alternative to PPCI in early presenters only. The individual decision to treat an early presenter with PPCI or TL requires the evaluation of the time delay between potential start of TL or PPCI, the PCI-related delay (PRD). PRD is greatest, if TL is given in the prehospital setting. Until now, prehospital TL as ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4993637 Wed, 29 Jun 2011 15:50:03 +0100 4993637 http://www.medworm.com/index.php?rid=4993638&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk15071p8586v7k24%2F Conclusions  High-dose N-ACC does not provide additional benefit over placebo with respect to Cys-C defined CIN in STEMI patients undergoing primary PCI. The magnitude of increase in Cys-C serum levels in the early course after STEMI is a predictor of medium-term MACE. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0338-8Authors Michal Droppa, Department of Internal Medicine/Cardiology, University of Leipzig, Heart Center, Strümpellstr. 39, 04289 Leipzig, GermanySteffen Desch, Department of Internal Medicine/Cardiology, University of Leipzig, Heart Center, Strümpellstr. 39, 04289 Leipzig, GermanyPatrick Blase, Department of Internal Medicine/Cardiology, University of Leipzig, Heart Center, Strümpellstr. 39, 04289 Leipzig, GermanyIngo Eitel, Department ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4993638 Tue, 28 Jun 2011 06:06:24 +0100 4993638 http://www.medworm.com/index.php?rid=4977526&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvu5506636m8048p5%2F Conclusion  RMN-guided PV ablation provides comparable acute and long-term success rates as compared to manual navigation. Procedural complication rates are similar. The use of RMN is associated with markedly reduced fluoroscopy time, but prolonged ablation and procedure duration. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0333-0Authors Lars Lüthje, Division of Cardiology and Pulmology, Heart Center, University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, GermanyDirk Vollmann, Division of Cardiology and Pulmology, Heart Center, University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, GermanyJoachim Seegers, Division of Cardiology and Pulmology, Heart Center, University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, GermanyMar... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4977526 Sat, 25 Jun 2011 05:41:55 +0100 4977526 http://www.medworm.com/index.php?rid=4970159&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8116p202k04g78kp%2F Conclusions  Repair for AV endocarditis yields excellent results. It is associated with low operative mortality and provides satisfactory early and long-term survival and favorable freedom from recurrent endocarditis and repeat operation. It should be considered as the primary surgical option in these patients, and AV replacement should be performed only in cases of severe AV destruction that renders repair techniques impossible. Content Type Journal ArticlePages 1-10DOI 10.1007/s00392-011-0331-2Authors Michele Musci, Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 13353 Berlin, GermanyMichael Hübler, Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, 1335... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4970159 Fri, 24 Jun 2011 16:14:41 +0100 4970159 http://www.medworm.com/index.php?rid=4970160&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw670v55800p67553%2F Conclusions  Despite a sound rationale to choose stent size, optimize stent expansion and guide kissing inflation, IVUS usage during PCI for coronary bifurcation lesions was not associated with significant clinical benefits in this large retrospective study. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0336-xAuthors Giuseppe Biondi-Zoccai, Division of Cardiology, University of Modena and Reggio Emilia, Via del Pozzo 71, 41124 Modena, ItalyImad Sheiban, Division of Cardiology, University of Turin, Turin, ItalyEnrico Romagnoli, Division of Cardiology, Policlinico Casilino, Rome, ItalyStefano De Servi, Dipartimento Cardiovascolare, Ospedale di Legnano, Milan, ItalyCorrado Tamburino, Division of Cardiology, Ferrarotto Hospital, University of Catania, Catani... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4970160 Fri, 24 Jun 2011 05:45:11 +0100 4970160 http://www.medworm.com/index.php?rid=4970161&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh53w5726q6024378%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s00392-011-0328-xAuthors Uwe Raaz, Department of Medicine III, University Clinics of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097 Halle Saale, GermanyMichael Buerke, Department of Medicine III, University Clinics of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097 Halle Saale, GermanyDietrich Stoevesandt, Department of Radiology, University Clinics of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097 Halle Saale, GermanyPhilipp Thermann, Department of Medicine I, University Clinics of the Martin-Luther-University Halle-Wittenberg, Ernst-Grube-Str. 40, 06097 Halle Saale, GermanyIvar Friedrich, Department of Cardiothoracic Surgery, University Clinics of the Marti... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4970161 Thu, 23 Jun 2011 16:32:54 +0100 4970161 http://www.medworm.com/index.php?rid=4970162&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4310725m6rr1r0r4%2F Conclusion  Coronary angiography and percutaneous coronary interventions under mild therapeutic hypothermia were safe in this small cohort and were performed without hypothermia-induced vasospasm, relevant rhythm events or bleeding complications. This result has to be confirmed in a large series of patients. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0334-zAuthors Ralf Koester, Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg, GermanyJan Kaehler, Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg, GermanyAchim Barmeyer, Clinic for General and Interventional Cardiology, University Heart Center Hamburg, Martinistrasse 52, ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4970162 Tue, 21 Jun 2011 18:34:09 +0100 4970162 http://www.medworm.com/index.php?rid=4970163&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqr32v874682mx2l0%2F Abstract  Essential hypertension, insulin resistance, heart failure, congestion, diuretic resistance, and functional renal disease are all characterized by excessive central sympathetic drive. The contribution of the kidney’s somatic afferent nerves, as an underlying cause of elevated central sympathetic drive, and the consequences of excessive efferent sympathetic signals to the kidney itself, as well as other organs, identify the renal sympathetic nerves as a uniquely logical therapeutic target for diseases linked by excessive central sympathetic drive. Clinical studies of renal denervation in patients with resistant hypertension using an endovascular radiofrequency ablation methodology have exposed the sympathetic link between these conditions. Renal denervation could ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4970163 Tue, 21 Jun 2011 18:01:37 +0100 4970163 http://www.medworm.com/index.php?rid=4946487&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhh4432j47270746r%2F Conclusion  Bone marrow-derived stem cell therapy yields smaller EDWT when compared with placebo patients suggesting a positive effect on maladaptive hypertrophy of viable myocardium. This notion is supported by the enhanced regional contractility within the BMC group which is inversely correlated with EDWT. Content Type Journal ArticlePages 1-10DOI 10.1007/s00392-011-0330-3Authors Andreas Rolf, Department of Cardiology, Kerckhoff-Heart Center, Benekestrasse 2-8, 61231 Bad Nauheim, GermanyBirgit Assmus, Department of Cardiology, University Hospital, Frankfurt, GermanyVolker Schächinger, Department of Cardiology, Klinikum Fulda, Fulda, GermanyJohannes Rixe, Department of Cardiology, Kerckhoff-Heart Center, Benekestrasse 2-8, 61231 Bad Nauheim, GermanySusanne Möllman... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4946487 Fri, 17 Jun 2011 12:00:06 +0100 4946487 http://www.medworm.com/index.php?rid=4923190&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F62550347w64n4148%2F This article provides information and commentaries on trials, which were presented during the Hotline Sessions at the 77th annual spring meeting of the German Society of Cardiology in Mannheim, Germany, from April 27 to 30, 2011. This article summarizes a number of important, novel clinical trials in the field of cardiovascular medicine. The comprehensive summaries have been generated from the oral presentation from the authors as previously reported [1] and should provide the readers with the most comprehensive information of relevant publications. The data were presented by leading experts in the field with relevant positions in the trials. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0325-0Authors J. M. Sinning, Medizinische Klinik und Poliklinik II, Innere Med... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4923190 Wed, 08 Jun 2011 15:46:59 +0100 4923190 http://www.medworm.com/index.php?rid=4913453&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9377468135183301%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-011-0326-zAuthors Karim Ibrahim, Heart Center Dresden, University Hospital, Dresden, GermanyMarian Christoph, Heart Center Dresden, University Hospital, Dresden, GermanyJoachim Nicolai, Heart Center Dresden, University Hospital, Dresden, GermanyHagen Schroetter, Heart Center Dresden, University Hospital, Dresden, GermanyThorsten Schmidt, Heart Center Dresden, University Hospital, Dresden, GermanyUtz Kappert, Heart Center Dresden, University Hospital, Dresden, GermanySteffen Schoen, Heart Center Dresden, University Hospital, Dresden, GermanyRuth H. Strasser, Heart Center Dresden, University Hospital, Dresden, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research i... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4913453 Sun, 05 Jun 2011 05:46:07 +0100 4913453 http://www.medworm.com/index.php?rid=4903992&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk6l86x5v20576k08%2F Conclusions  The MODI fY trial is the first application of ivabradine as a pure heart rate reducing agent in MODS patients. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0323-2Authors Sebastian Nuding, Department of Medicine III (Cardiology, Angiology, Medical Intensive Care Medicine, Geriatrics, Sports Medicine), University Clinics Halle (Saale), Medical Faculty of the Martin-Luther University Halle-Wittenberg, Ernst-Grube-Straße 40, 06097 Halle (Saale), GermanyHenning Ebelt, Department of Medicine III (Cardiology, Angiology, Medical Intensive Care Medicine, Geriatrics, Sports Medicine), University Clinics Halle (Saale), Medical Faculty of the Martin-Luther University Halle-Wittenberg, Ernst-Grube-Straße 40, 06097 Halle (Saale), GermanyRobert S. Hoke,... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4903992 Fri, 03 Jun 2011 06:01:44 +0100 4903992 http://www.medworm.com/index.php?rid=4903993&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8u28042618v8r771%2F Conclusions  The 5-year follow-up of the TOPCARE-AMI trial provides reassurance with respect to the long-term safety of intracoronary cell therapy and suggests favorable effects on LV function. Content Type Journal ArticlePages 1-10DOI 10.1007/s00392-011-0327-yAuthors David M. Leistner, Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, GermanyUlrich Fischer-Rasokat, Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, GermanyJörg Honold, Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Theodor Stern Kai 7, 60590 Frankfurt, GermanyFlorian H. Seeger, Division of Cardiology, Department of Medicine III, Goe... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4903993 Thu, 02 Jun 2011 05:59:55 +0100 4903993 http://www.medworm.com/index.php?rid=4903994&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu61h332081777361%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00392-011-0324-1Authors C. S. Zuern, Department of Cardiology, University Hospital of Tübingen, Otfried Müller-Strasse 10, 72076 Tübingen, GermanyJ. Schreieck, Department of Cardiology, University Hospital of Tübingen, Otfried Müller-Strasse 10, 72076 Tübingen, GermanyH. J. Weig, Department of Cardiology, University Hospital of Tübingen, Otfried Müller-Strasse 10, 72076 Tübingen, GermanyM. Gawaz, Department of Cardiology, University Hospital of Tübingen, Otfried Müller-Strasse 10, 72076 Tübingen, GermanyA. E. May, Department of Cardiology, University Hospital of Tübingen, Otfried Müller-Strasse 10, 72076 Tübingen, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clin... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4903994 Tue, 24 May 2011 05:51:35 +0100 4903994 http://www.medworm.com/index.php?rid=4790252&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frm8q7150q4367203%2F Conclusion  BNP-R was found to be highly accurate for the early diagnosis of TMC. Content Type Journal ArticlePages 1-10DOI 10.1007/s00392-011-0319-yAuthors Amir M. Nia, Department of Internal Medicine III, University of Cologne, Kerpener Str. 62, 50937 Cologne, GermanyNatig Gassanov, Department of Internal Medicine III, University of Cologne, Kerpener Str. 62, 50937 Cologne, GermanyKristina M. Dahlem, Department of Internal Medicine III, University of Cologne, Kerpener Str. 62, 50937 Cologne, GermanyEvren Caglayan, Department of Internal Medicine III, University of Cologne, Kerpener Str. 62, 50937 Cologne, GermanyMartin Hellmich, Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne, Cologne, GermanyErland Erdmann, Department of Internal M... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4790252 Tue, 03 May 2011 05:54:19 +0100 4790252 http://www.medworm.com/index.php?rid=4782300&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F808715vl0n5n5320%2F Conclusions  Patients with AF managed in primary care often receive guideline-conforming therapy including antithrombotic therapy, rate control and rhythm control (numbers given above). Despite this apparent adherence, almost half of the patients were hospitalized in the year prior to enrollment, suggesting that the therapies applied do not stabilize patients sufficiently to keep them out of hospital. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0320-5Authors Thomas Meinertz, Klinik und Poliklinik für Allgemeine und Interventionelle Kardiologie, Universitäres Herzzentrum Hamburg, Hamburg, GermanyWilhelm Kirch, Institut für Klinische Pharmakologie, Medizinische Fakultät, Technische Universität, Dresden, GermanyLudger Rosin, Medizinische Abteilung,... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4782300 Sat, 30 Apr 2011 23:40:42 +0100 4782300 http://www.medworm.com/index.php?rid=4782301&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu17lk48361383838%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-011-0316-1Authors M. Merkel, Karlsruhe, GermanyT. Riexinger, Karlsruhe, GermanyC. Schmitt, Städtisches Klinikum Karlsruhe, Karlsruhe, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4782301 Fri, 29 Apr 2011 23:19:23 +0100 4782301 http://www.medworm.com/index.php?rid=4782302&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw03w3616042334nt%2F Conclusion  Clopidogrel low response is present in 1/10 patients and more frequent in ACS-PCI. MEA-guided optimizing of thienopyridine therapy is feasible and results in a very low specific MACCE rate. Low response to all thienopyridines is rare. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0321-4Authors Tobias Behr, Medizinische Klinik, Klinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, GermanyBernhard Kuch, Medizinische Klinik, Klinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, GermanyWerner Behr, Institut für Laboratoriumsmedizin, Klinikum Augsburg, Augsburg, GermanyWolfgang von Scheidt, Medizinische Klinik, Klinikum Augsburg, Stenglinstr. 2, 86156 Augsburg, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4782302 Fri, 29 Apr 2011 15:47:19 +0100 4782302 http://www.medworm.com/index.php?rid=4754899&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft540620067177114%2F This article provides information and commentaries on trials which were presented at the Hotline and Clinical Trial Update Sessions during the Late Breaking Clinical Trial Sessions at the 60th annual meeting of the American College of Cardiology in New Orleans, USA, from 2nd April to 5th April 2011. This article gives an overview on a number of novel clinical trials in the field of cardiovascular medicine, which were presented. The comprehensive summaries have been generated from the oral presentation and the webcasts of the American College of Cardiology, similar as previousely reported (Gensch et al. Clin Res Cardiol 100:1–9, 2011; Lenski et al. Clin Res Cardiol 99:679–692, 2010) and should provide the readers with the most comprehensive information of relevant publications. The... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4754899 Fri, 22 Apr 2011 16:02:52 +0100 4754899 http://www.medworm.com/index.php?rid=4754900&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F64k5726032l1717h%2F Conclusion  In clinical practice, elderly patients with ACS undergoing PCI receive significantly less intensive antithrombotic treatment. In terms of successful PCI, there was no significant difference between the age groups in patients with elective PCI, UA and NSTEMI. The higher in-hospital mortality of the elderly in all patient groups is most likely due to a higher rate of comorbidities. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0311-6Authors Arne Kristian Schwarz, Herzzentrum Ludwigshafen, Medizinische Klinik B, Bremserstrasse 79, 67063 Ludwigshafen, GermanyRalf Zahn, Herzzentrum Ludwigshafen, Medizinische Klinik B, Bremserstrasse 79, 67063 Ludwigshafen, GermanyMatthias Hochadel, Institut für Herzinfarktforschung Ludwigshafen, Bremserstrasse 7... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4754900 Thu, 21 Apr 2011 06:13:29 +0100 4754900 http://www.medworm.com/index.php?rid=4725494&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F32p735158x9r0r33%2F Conclusion  NT-proBNP can serve as a screening tool in various primarily non-cardiac paediatric diseases. Together with the clinical picture, a high level suggests further assessment by a paediatric cardiologist. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0317-0Authors Eva Welisch, Department of Paediatrics, Children’s Hospital, London Health Science Centre, University of Western Ontario, 800 Commissioners Road East, London, ON N6A 5W9, CanadaKambiz Norozi, Department of Paediatrics, Children’s Hospital, London Health Science Centre, University of Western Ontario, 800 Commissioners Road East, London, ON N6A 5W9, CanadaRalf Rauch, Department of Paediatrics, Children’s Hospital, London Health Science Centre, University of Western Ontario, 800 Comm... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4725494 Wed, 13 Apr 2011 14:36:35 +0100 4725494 http://www.medworm.com/index.php?rid=4710143&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq6j3v60337557738%2F Conclusions  In contrast to elective settings, the risk of access site-related vascular complications is significantly increased after application of the VCD Angio-Seal™ in patients undergoing emergency catheterizations for NSTEMI/STEMI compared with manual compression. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0313-4Authors Emilia Stegemann, Medizinische Klinik I, Medical Faculty, University RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, GermanyRainer Hoffmann, Medizinische Klinik I, Medical Faculty, University RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, GermanySteven Marso, Saint Luke’s Hospital, Kansas City, USABerthold Stegemann, Medizinische Klinik I, Medical Faculty, University RWTH Aachen, Pauwelsstr. 30, 52074 Aachen, GermanyNikolaus Marx, Me... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4710143 Mon, 11 Apr 2011 05:37:16 +0100 4710143 http://www.medworm.com/index.php?rid=4710144&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa1414752622k1040%2F Abstract  Soluble TWEAK is a member of the TNF-alpha family of cytokines that has been shown to predict mortality in patients with heart failure. Pulmonary artery hypertension is a devastating disease, in which right ventricular function has been shown to be the major determinant of prognosis. In this hypothesis-generating study, we sought to evaluate the potential usefulness of sTWEAK in the prediction of disease severity in patients with pulmonary artery hypertension. We therefore conducted a retrospective analysis of sTWEAK serum levels in 95 stable patients with PAH. For all patients data on hemodynamic parameters, biomarkers and functional exercise tests were available. Compared to controls, patients with PAH showed significantly decreased levels of sTWEAK [median 314&... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4710144 Sun, 10 Apr 2011 15:40:48 +0100 4710144 http://www.medworm.com/index.php?rid=4710145&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa4263j752vt28250%2F Conclusion  Abrupt clopidogrel cessation after 1 year of clopidogrel treatment results in ADP specific platelet hyperreactivity between 2 and 6 weeks post withdrawal. This mechanism may contribute to explain increased rates of stent thrombosis at this time as it was observed in clinical studies. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0310-7Authors Philipp Diehl, Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr. 55, 79106 Freiburg, GermanyChristoph Halscheid, Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr. 55, 79106 Freiburg, GermanyChristoph Olivier, Department of Cardiology and Angiology, University Hospital Freiburg, Hugstetterstr. 55, 79106 Freiburg, GermanyThoma... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4710145 Sat, 09 Apr 2011 05:55:39 +0100 4710145 http://www.medworm.com/index.php?rid=4710146&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F458465m273681h72%2F Conclusion  Resuscitated patients show a significantly reduced HRV before, during and after TH. Compared to survivors, the non-survivors show a further and significantly decrease of HRV immediately after hypothermia. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0314-3Authors R. Pfeifer, Department of Internal Medicine I, University Hospital Jena, Erlanger Allee 101, 07740 Jena, GermanyJ. Hopfe, Department of Medical Engineering and Biotechnology, University of Applied Sciences Jena, Carl-Zeiss-Promenade 2, 07745 Jena, GermanyC. Ehrhardt, Department of Internal Medicine I, University Hospital Jena, Erlanger Allee 101, 07740 Jena, GermanyM. Goernig, Department of Geriatrics, University Hospital Jena, Bachstrasse 18, 07740 Jena, GermanyH. R. Figulla, Depar... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4710146 Fri, 08 Apr 2011 07:06:56 +0100 4710146 http://www.medworm.com/index.php?rid=4698212&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx3510249715v2616%2F Abstract  Both, anemia and vitamin D deficiency are prevalent in patients with heart failure. According to recent evidence, vitamin D may stimulate erythropoiesis. We measured circulating 25-hydroxyvitamin D (25[OH]D), 1,25-dihydroxyvitamin D (1,25[OH]2D) and hemoglobin (Hb) in a cross-sectional study in 364 end-stage heart failure patients awaiting cardiac transplantation, of whom 52.6% met the criteria for anemia (Hb < 13 g/dl in males and <12 g/dl in females). None of the patients were on erythrocyte-stimulating agents. Of the study cohort, 87.8% had 25(OH)D concentrations below 50 nmol/l. The mean Hb concentrations were significantly reduced in the lower tertiles of 25(OH)D and 1,25(OH)2D (P < 0.001). In multivariate-adjusted lo... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4698212 Thu, 07 Apr 2011 06:02:37 +0100 4698212 http://www.medworm.com/index.php?rid=4686152&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2775n93080441652%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00392-011-0315-2Authors Michael Gotzmann, Medizinische Klinik II, Kardiologie und Angiologie, Berufsgenossenschaftliche Kliniken Bergmannsheil, Klinikum der Ruhr-Universität, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, GermanyAndreas Mügge, Medizinische Klinik II, Kardiologie und Angiologie, Berufsgenossenschaftliche Kliniken Bergmannsheil, Klinikum der Ruhr-Universität, Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4686152 Sun, 03 Apr 2011 05:54:21 +0100 4686152 http://www.medworm.com/index.php?rid=4671496&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg227322m668t3851%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s00392-011-0297-0Authors Michael Möller, Department of Cardiology and Intensive Care, Klinikum Kassel, Mönchebergstraße, 41-43, 34125 Kassel, GermanyJens Völz, Department of Cardiology and Intensive Care, Klinikum Kassel, Mönchebergstraße, 41-43, 34125 Kassel, GermanyRobert Paliege, Department of Cardiology and Intensive Care, Klinikum Kassel, Mönchebergstraße, 41-43, 34125 Kassel, GermanyCorinna Lenz, Department of Cardiology and Intensive Care, Klinikum Kassel, Mönchebergstraße, 41-43, 34125 Kassel, GermanyDaniela Berger, Department of Cardiology and Intensive Care, Klinikum Kassel, Mönchebergstraße, 41-43, 34125 Kassel, GermanyRainer Gradaus, Department of Cardiology and Intensive Care, Klinikum Kassel, Mönchebergstraße,... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4671496 Thu, 31 Mar 2011 07:20:36 +0100 4671496 http://www.medworm.com/index.php?rid=4644106&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyv63p8u4660515p1%2F Conclusion  During World Cup Soccer, the number of deaths due to myocardial infarction was not measurably increased compared to a matched control period. Thus, we could not demonstrate a translation of a stress-induced increase of cardiac morbidity into a noticeable increase in mortality. However, our findings are based on a public mortality registry, which may be flawed in many ways, regarding ascertainment of causes of death, in particular. Content Type Journal ArticlePages 1-6DOI 10.1007/s00392-011-0302-7Authors U. Wilbert-Lampen, Medizinische Klinik und Poliklinik I, Klinikum Grosshadern, Ludwig-Maximilians-Universität, Campus Grosshadern, Marchioninistr.15, 81377 Munich, GermanyT. Nickel, Medizinische Klinik und Poliklinik I, Klinikum Grosshadern, Ludwig-Maxim... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4644106 Thu, 24 Mar 2011 09:05:18 +0100 4644106 http://www.medworm.com/index.php?rid=4644107&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frl883q5922512816%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-011-0309-0Authors Martin Koestenberger, Department of Pediatrics, Division of Pediatric Cardiology, Medical University Graz, Auenbruggerplatz 30, 8036 Graz, AustriaBert Nagel, Department of Pediatrics, Division of Pediatric Cardiology, Medical University Graz, Auenbruggerplatz 30, 8036 Graz, AustriaVerena Halb, Department of Pediatrics, Division of Pediatric Cardiology, Medical University Graz, Auenbruggerplatz 30, 8036 Graz, AustriaAndreas Gamillscheg, Department of Pediatrics, Division of Pediatric Cardiology, Medical University Graz, Auenbruggerplatz 30, 8036 Graz, Austria Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4644107 Wed, 23 Mar 2011 16:56:42 +0100 4644107 http://www.medworm.com/index.php?rid=4616502&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F46m1g6u323x15555%2F Conclusions  The S-ICD system can be implanted without the use of fluoroscopy by using anatomical landmarks only. Episodes of VF were accurately detected using subcutaneous signals, and all induced and clinical episodes were successfully converted. The S-ICD system is a viable alternative to conventional ICD systems for selected patients. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0303-6Authors Lara Dabiri Abkenari, Department of Cardiology, Erasmus MC, Rotterdam, The NetherlandsDominic A. M. J. Theuns, Department of Cardiology, Erasmus MC, Rotterdam, The NetherlandsSuzanne D. A. Valk, Department of Cardiology, Erasmus MC, Rotterdam, The NetherlandsYves Van Belle, Department of Cardiology, Erasmus MC, Rotterdam, The NetherlandsNatasja M. de Groot, De... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4616502 Thu, 17 Mar 2011 18:29:38 +0100 4616502 http://www.medworm.com/index.php?rid=4616503&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj22816833657w863%2F Conclusions  In clinical practice, DES was very frequently used off-label. After adjustment for confounding variables, off-label use was not associated with an increase of adverse events. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0301-8Authors Timm Bauer, Department of Cardiology, Medizinische Klinik B, Herzzentrum Ludwigshafen, Bremserstrasse 79, 67063 Ludwigshafen, GermanyChristoph A. Nienaber, Universität Rostock, Rostock, GermanyIbrahim Akin, Universität Rostock, Rostock, GermanyKarl-Heinz Kuck, Asklepios-Klinik St. Georg, Hamburg, GermanyMatthias Hochadel, Institut für Herzinfarktforschung an der Universität Heidelberg, Ludwigshafen, GermanyJochen Senges, Institut für Herzinfarktforschung an der Universität Heidelberg, Ludwigshafen, German... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4616503 Thu, 17 Mar 2011 18:29:36 +0100 4616503 http://www.medworm.com/index.php?rid=4616505&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh1p057826r33264j%2F Conclusion  The impact of comorbidities on physical impairment is higher in HFpEF than in HFrEF. This should be considered in the differential diagnosis and in the treatment of patients with HFpEF. Content Type Journal ArticlePages 1-10DOI 10.1007/s00392-011-0305-4Authors Frank Edelmann, Department of Cardiology and Pneumology, University of Göttingen, 37075 Göttingen, GermanyRaoul Stahrenberg, Department of Cardiology and Pneumology, University of Göttingen, 37075 Göttingen, GermanyGötz Gelbrich, Coordination Center for Clinical Trials, University of Leipzig, Leipzig, GermanyKathleen Durstewitz, Department of Cardiology and Pneumology, University of Göttingen, 37075 Göttingen, GermanyChristiane E. Angermann, Department of Internal Medicine I, Center for Cardio... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4616505 Thu, 17 Mar 2011 18:29:34 +0100 4616505 http://www.medworm.com/index.php?rid=4616504&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr876gt804x4tk82g%2F Conclusions  Examining consistency of effect across multiple clinical endpoints in a proof-of-concept study may identify efficacious therapies and enable dose selection for confirmatory trials. The merit of the approach described requires confirmation through prospective application in designing future studies. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0304-5Authors Beth A. Davison, Momentum Research, Inc., Durham, NC USAGad Cotter, Momentum Research, Inc., Durham, NC USAHengrui Sun, Momentum Research, Inc., Durham, NC USALi Chen, Department of Biostatistics, School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC USAJohn R. Teerlink, Section of Cardiology, San Francisco Veterans Affairs Medical Center, University of Ca... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4616504 Thu, 17 Mar 2011 18:29:34 +0100 4616504 http://www.medworm.com/index.php?rid=4611461&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm66l6jv56l04rq04%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-011-0306-3Authors Thomas Scheffold, Department Biobank/Kardiogenetik, Institut Für Herzinfarktforschung Ludwigshafen an der Universität Heidelberg, Bremserstr. 79, 67063 Ludwigshafen/Rhein, GermanyStephan Waldmüller, Institut für Herzkreislaufforschung, Universität Witten/Herdecke, 44227 Dortmund, GermanyKonstantin Borisov, Department of Cardiology and Surgery, Rehabilitation Center of the Executive Office of the President of Russian Federation, 143088 Moscow, Russia Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4611461 Wed, 16 Mar 2011 11:52:48 +0100 4611461 http://www.medworm.com/index.php?rid=4611462&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg8773313t72w5730%2F Content Type Journal ArticlePages 1-1DOI 10.1007/s00392-011-0308-1Authors Robert Dalla Pozza, Department of Pediatric Cardiology, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, GermanyDaniel Theisen, Department of Clinical Radiology, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, GermanyHeinrich Netz, Department of Pediatric Cardiology, Klinikum Grosshadern, Ludwig-Maximilians-University, Munich, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4611462 Tue, 15 Mar 2011 18:44:53 +0100 4611462 http://www.medworm.com/index.php?rid=4594130&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd739065078t10132%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00392-011-0307-2Authors Sofiene Rekik, Cardiovascular Department, Clinique Rhône Durance, Avignon, FranceJérôme Brunet, Cardiovascular Department, Clinique Rhône Durance, Avignon, FranceFrançois Xavier Hager, Cardiovascular Department, Clinique Rhône Durance, Avignon, FranceGilles Bayet, Cardiovascular Department, Clinique Rhône Durance, Avignon, FranceLaurent Meille, Cardiovascular Department, Clinique Rhône Durance, Avignon, FranceJean Michel Quatre, Cardiovascular Department, Clinique Rhône Durance, Avignon, FranceJoël Sainsous, Cardiovascular Department, Clinique Rhône Durance, Avignon, France Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4594130 Sat, 12 Mar 2011 16:53:21 +0100 4594130 http://www.medworm.com/index.php?rid=4566971&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy21t415x4r13vm2n%2F Conclusion  Although abciximab reduced the 30-day and 1-year incidence of major adverse cardiac events in patients with NSTE-ACS undergoing primary PCI after pre-treatment with a 600-mg loading dose of clopidogrel, the agent did not improve or impact on the evolution of LVEF over 6–8 months of follow-up. Content Type Journal ArticlePages 1-9DOI 10.1007/s00392-011-0299-yAuthors Stefanie Schulz, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyJulinda Mehilli, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyGjin Ndrepepa, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyFranz Dotzer, Klinikum Garmisch-Partenkirchen, Zentrum für Innere Medizin/Kardiolo... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4566971 Mon, 07 Mar 2011 17:03:19 +0100 4566971 http://www.medworm.com/index.php?rid=4561589&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm5461rw8884g2356%2F Conclusion  Anti-Ig IA appears to be an effective therapeutic option for patients with advanced TAO. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0298-zAuthors Gert Baumann, Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie Charité, Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117 Berlin, GermanyVerena Stangl, Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie Charité, Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117 Berlin, GermanyPeter Klein-Weigel, DRK-Kliniken Berlin, Berlin, GermanyKarl Stangl, Medizinische Klinik mit Schwerpunkt Kardiologie und Angiologie Charité, Universitätsmedizin Berlin, Campus Mitte, Charitéplatz 1, 10117 Berlin, GermanyMichael Laule, Medizinische Klinik mit Schwerp... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4561589 Sat, 05 Mar 2011 07:04:10 +0100 4561589 http://www.medworm.com/index.php?rid=4561590&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk248u43438h71943%2F Conclusion  In complex interventional edge-to-edge repair with the MitraClip device requiring optimal spatial information RT 3-D TEE allows improved guidance of the procedure. RT 3-D TEE guidance compared with 2-D TEE guidance alone resulted in greater operator confidence to adequately perform the procedure. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0296-1Authors Ertunc Altiok, Medical Clinic I, University RWTH Aachen, Pauwelsstraße 30, 52057 Aachen, GermanyMichael Becker, Medical Clinic I, University RWTH Aachen, Pauwelsstraße 30, 52057 Aachen, GermanySandra Hamada, Medical Clinic I, University RWTH Aachen, Pauwelsstraße 30, 52057 Aachen, GermanySebastian Reith, Medical Clinic I, University RWTH Aachen, Pauwelsstraße 30, 52057 Aachen, GermanyNi... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4561590 Thu, 03 Mar 2011 08:51:49 +0100 4561590 http://www.medworm.com/index.php?rid=4550233&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn402g5600nkum417%2F Abstract  Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a predominantly genetically determined and heritable form of cardiomyopathy that is characterized pathologically by the replacement of myocytes by adipose and fibrous tissue and leads to right ventricular failure, arrhythmias, and sudden cardiac death. The estimated prevalence of ARVC/D in the general population ranges from 1 in 2,000 to 1 in 5,000, men are more frequently affected than women, with an approximate ratio of 3:1. ARVC/D can be inherited as an autosomal dominant disease with reduced penetrance and variable expression, autosomal recessive inheritance is also described. There have been 12 genes identified which are linked to ARVC/D, encoding several components of the cardiac desmosome... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4550233 Tue, 01 Mar 2011 07:10:35 +0100 4550233 http://www.medworm.com/index.php?rid=4541357&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm627041306823338%2F Conclusion  Hyperglycemia at admission in STEMI patients who are successfully treated by PCI is independently associated with the presence and extent of microvascular obstruction on contrast-enhanced CMR. Thus, microvascular obstruction as assessed by CMR may be a mechanism that relates admission hyperglycemia in acute STEMI to worse outcome. Content Type Journal ArticlePages 1-11DOI 10.1007/s00392-011-0290-7Authors Christoph J. Jensen, Department of Cardiology and Angiology, Elisabeth Hospital Essen, Klara-Kopp-Weg 1, 45138 Essen, GermanyHolger C. Eberle, Department of Cardiology and Angiology, Elisabeth Hospital Essen, Klara-Kopp-Weg 1, 45138 Essen, GermanyKai Nassenstein, Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4541357 Thu, 24 Feb 2011 08:01:58 +0100 4541357 http://www.medworm.com/index.php?rid=4513358&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5h14352mrl464216%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-011-0286-3Authors M. Wilbring, Department for Cardiovascular Surgery, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg, GermanyK. Alexiou, Department for Cardiothoracic Surgery, Heart Center Brandenburg, Ladeburger Strasse 17, 16321 Bernau, GermanyH. Reichenspurner, Department for Cardiovascular Surgery, University Heart Center Hamburg, Martinistrasse 52, 20246 Hamburg, GermanyK. Matschke, Department for Cardiac Surgery, University Heart Center Dresden, Fetscherstrasse 76, 01307 Dresden, GermanyS. M. Tugtekin, Department for Cardiac Surgery, University Heart Center Dresden, Fetscherstrasse 76, 01307 Dresden, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Cl... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4513358 Sat, 19 Feb 2011 18:25:54 +0100 4513358 http://www.medworm.com/index.php?rid=4502682&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx203j2vhq45480q8%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s00392-011-0289-0Authors Philipp Ehlermann, Innere Medizin III-Kardiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyStephanie Lehrke, Innere Medizin III-Kardiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyTheano Papavassiliu, I. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, GermanyBenjamin Meder, Innere Medizin III-Kardiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyMartin Borggrefe, I. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, GermanyHugo A. Katus, Innere Medizin III-Kardiologie, Universitätsklinikum Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyRainer ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4502682 Thu, 17 Feb 2011 06:54:03 +0100 4502682 http://www.medworm.com/index.php?rid=4502683&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn70508n054q4t584%2F Conclusion  While short-term biological variation of hsTnT is low, it becomes relatively more important for intermediate follow-up. It is not related to aetiology of heart failure. The corresponding indices of individuality indicate high individuality of values. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0285-4Authors Lutz Frankenstein, Department of Cardiology, Angiology, Pulmonology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyAndrew Remppis, Department of Cardiology, Angiology, Pulmonology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyEvangelos Giannitis, Department of Cardiology, Angiology, Pulmonology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, GermanyJoerdis... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4502683 Thu, 17 Feb 2011 06:54:02 +0100 4502683 http://www.medworm.com/index.php?rid=4490634&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9768p77h2106045w%2F Conclusions  In this pilot study, aerosolized iloprost had a favorable safety profile. Larger trials are needed to compare its efficacy to iNO for the treatment of perioperative pulmonary hypertension. However, neither treatment alone abolished the occurrence of PHTCs. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0284-5Authors Tsvetomir Loukanov, Department of Cardiac Surgery, University of Heidelberg Medical Centre, INF 110, 69120 Heidelberg, GermanyDietrich Bucsenez, Department of Pediatric Cardiology, University Medical Center, Heidelberg, GermanyWolfgang Springer, Department of Pediatric Cardiology, University Medical Center, Heidelberg, GermanyChristian Sebening, Department of Cardiac Surgery, University of Heidelberg Medical Centre, INF 110, 6912... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4490634 Mon, 14 Feb 2011 07:13:49 +0100 4490634 http://www.medworm.com/index.php?rid=4490635&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8380178r641nml6v%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00392-011-0293-4Authors Christof Burgdorf, Department of Internal Medicine II, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, GermanyPeter Hunold, Clinic for Radiology and Nuclear Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, GermanyPeter W. Radke, Department of Internal Medicine II, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, GermanyHeribert Schunkert, Department of Internal Medicine II, University Hospital Schleswig-Holstein, Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, GermanyVolkhard Kurowski, Department of Internal Medicine II, University Hospital Schleswig-Holstein, Cam... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4490635 Fri, 11 Feb 2011 11:50:22 +0100 4490635 http://www.medworm.com/index.php?rid=4490636&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd789w1u75k762338%2F Conclusion  The responsiveness to β-blockers with respect to cardiac contractility is determined by the Arg389Gly β1AR gene polymorphism. These findings offer a molecular explanation for interindividual differences in the responsiveness to β-blocker treatment in humans. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0288-1Authors Michael Huntgeburth, Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50937 Cologne, GermanyKarl La Rosée, Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50937 Cologne, GermanyHenrik ten Freyhaus, Klinik III für Innere Medizin, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50937 Cologne, GermanyMichael Böhm, Klinik für Innere Mediz... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4490636 Fri, 11 Feb 2011 06:44:55 +0100 4490636 http://www.medworm.com/index.php?rid=4490638&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F43308pj772858130%2F Conclusions  This study demonstrated a weak correlation of sE-selectin level with inflammatory markers and prediction of short-term mortality in diabetic CHF patients. Elevated serum sE-selectin levels and concomitantly increased NT-proBNP concentrations have additive predictive power in CHF. This suggests that parallel activation of various pathophysiological pathways confers increased risk of adverse outcome in CHF. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0283-6Authors Judit Czúcz, Research Laboratory, 3rd Department of Internal Medicine, Szentágothai Knowledge Center, Semmelweis University, Budapest, HungaryLászló Cervenak, Research Group of Inflammation Biology and Immunogenomics, Hungarian Academy of Sciences, Budapest, HungaryZsolt För... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4490638 Fri, 11 Feb 2011 06:44:54 +0100 4490638 http://www.medworm.com/index.php?rid=4490637&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc6523k29044mwm84%2F Conclusion  The majority of AMIs in winter tourists happens within the first 2 days after arrival and within the first 2 days of physical activity. Content Type Journal ArticlePages 1-6DOI 10.1007/s00392-011-0294-3Authors G. Klug, Department of Internal Medicine III, University Clinic of Internal Medicine III/Cardiology, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, AustriaS. Schenk, Department of Internal Medicine III, University Clinic of Internal Medicine III/Cardiology, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, AustriaJ. Dörler, Department of Internal Medicine III, University Clinic of Internal Medicine III/Cardiology, Medical University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, AustriaA. Mayr, Department... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4490637 Fri, 11 Feb 2011 06:44:54 +0100 4490637 http://www.medworm.com/index.php?rid=4471112&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkmvp368325q44473%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s00392-011-0291-6Authors Ali Yilmaz, Division of Cardiology, Robert-Bosch-Krankenhaus, Auerbachstrasse 110, 70376 Stuttgart, GermanyHans-Jürgen Gdynia, Department of Neurology, University of Ulm, Ulm, GermanyMatthias Ponfick, Department of Neurology, University of Ulm, Ulm, GermanyAlbert C. Ludolph, Department of Neurology, University of Ulm, Ulm, GermanySabine Rösch, Division of Cardiology, Robert-Bosch-Krankenhaus, Auerbachstrasse 110, 70376 Stuttgart, GermanyUdo Sechtem, Division of Cardiology, Robert-Bosch-Krankenhaus, Auerbachstrasse 110, 70376 Stuttgart, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4471112 Thu, 10 Feb 2011 19:55:53 +0100 4471112 http://www.medworm.com/index.php?rid=4471113&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3nwn36g707200826%2F Conclusion  This post-hoc analysis suggests the existence of an interaction between statin therapy before PCI and antithrombotic therapy during PCI. Patients receiving bivalirudin therapy at the time of PCI showed less periprocedural myocardial infarction when on pre-PCI statin therapy which has to be investigated in further studies. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-011-0282-7Authors Ahmed A. Khattab, Herz-Kreislauf-Zentrum, Segeberger Kliniken GmbH, Bad Segeberg, GermanyGjin Ndrepepa, Deutsches Herzzentrum, Technische Universität, Munich, GermanyStefanie Schulz, Deutsches Herzzentrum, Technische Universität, Munich, GermanyFranz-Josef Neumann, Herzzentrum, Bad Krozingen, GermanyJulinda Mehilli, Deutsches Herzzentrum, Technische Universität,... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4471113 Thu, 10 Feb 2011 19:55:52 +0100 4471113 http://www.medworm.com/index.php?rid=4471114&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp7254743757173p8%2F Conclusion  By using the parameter “afterload-related cardiac performance, ACP”, the impairment of cardiac function can be reliably quantified showing that septic cardiomyopathy occurs frequently and is of prognostic relevance in patients with septic MODS. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0292-5Authors Karl Werdan, Department of Medicine III, University of Halle (Saale), Ernst-Grube-Street 40, 06097 Halle, GermanyAnja Oelke, Department of Medicine III, University of Halle (Saale), Ernst-Grube-Street 40, 06097 Halle, GermanyStefan Hettwer, Department of Medicine III, University of Halle (Saale), Ernst-Grube-Street 40, 06097 Halle, GermanySebastian Nuding, Department of Medicine III, University of Halle (Saale), Ernst-Grube-Street 40, 0609... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4471114 Thu, 10 Feb 2011 06:49:29 +0100 4471114 http://www.medworm.com/index.php?rid=4451251&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy3520726640374j5%2F Conclusions  IA treatment improves endothelial function in patients with chronic iDCM. This effect is associated with a significant drop in circulating microparticles. The causal relationship between circulating microparticles and endothelial function is discussed. Content Type Journal ArticlePages 1-8DOI 10.1007/s00392-011-0287-2Authors Daniel Bulut, Division of Cardiology, St. Josef-Hospital, Ruhr-University Bochum, Gudrunstrasse 56, 44791 Bochum, GermanyMichael Scheeler, Herz- und Kreislaufzentrum der Ruhr-Universität, Standort BG Kliniken Bergmannsheil, Bürkle-de-la-Camp Platz 1, 44789 Bochum, GermanyLisa Marie Niedballa, Herz- und Kreislaufzentrum der Ruhr-Universität, Standort St. Josef-Hospital, Gudrunstraße 56, 44791 Bochum, GermanyThomas Miebach, Herz- un... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4451251 Sun, 06 Feb 2011 06:39:06 +0100 4451251 http://www.medworm.com/index.php?rid=4344155&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg4067l5l41g56874%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00392-010-0280-1Authors Samir M. Said, Cardiology, Otto-von-Guericke University, Leipzigerstrasse 44, 39120 Magdeburg, GermanyRuediger C. Braun-Dullaeus, Cardiology, Otto-von-Guericke University, Leipzigerstrasse 44, 39120 Magdeburg, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4344155 Tue, 11 Jan 2011 07:29:33 +0100 4344155 http://www.medworm.com/index.php?rid=4344156&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy07741460324t164%2F Conclusions  Hypertension in pregnancy is characterised by abnormalities in the vascular endothelium, with abnormal CECs and vWf that correlate with BPs. This may reflect dysfunctional processes that are counteracted with reparative attempts at restoring endothelial integrity. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-010-0277-9Authors V. J. Karthikeyan, University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, B18 7QH UKAndrew D. Blann, University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmingham, B18 7QH UKSabah Baghdadi, Department of Obstetrics and Gynaecology, City Hospital, Birmingham, B18 7QH UKDeirdre A. Lane, University of Birmingham Centre for Cardiovascular Sciences, City Hospital, Birmi... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4344156 Mon, 10 Jan 2011 16:09:47 +0100 4344156 http://www.medworm.com/index.php?rid=4327273&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh22v733n1h66g330%2F Conclusions  Sirolimus-eluting stents are highly effective in reducing the risk for major cardiac events and safe in diabetic patients with coronary artery disease. Content Type Journal ArticlePages 1-10DOI 10.1007/s00392-010-0278-8Authors Antoinette de Waha, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyAlban Dibra, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanySebastian Kufner, Deutsches Herzzentrum, Technische Universität, Lazarettstr. 36, 80636 Munich, GermanyDietrich Baumgart, Preventicum-Klinik für Diagnostik, Essen, GermanyManel Sabate, Cardiovascular Institute, Hospital de la Santa Creu i Sant Pau, Barcelona, SpainAleardo Maresta, Division of Cardiology, Interventional Center, S.... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4327273 Fri, 07 Jan 2011 14:48:14 +0100 4327273 http://www.medworm.com/index.php?rid=4327274&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F94k546693021j474%2F Conclusion  In TTC patients, high-anxiety trait is a common finding but it is not significantly more frequent than in patients with STEMI. Moreover, a high-anxiety trait seems to be neither associated with a worse clinical outcome nor a predictor of TTC. Our study do not support the routine evaluation of anxiety trait in patients with TTC. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-010-0276-xAuthors Stefano Del Pace, Department of Cardiology, Careggi Hospital, University of Florence, Viale Morgagni 85, 50134 Florence, ItalyGuido Parodi, Department of Cardiology, Careggi Hospital, University of Florence, Viale Morgagni 85, 50134 Florence, ItalyBenedetta Bellandi, Department of Cardiology, Careggi Hospital, University of Florence, Viale Morgagni 85, 50134 ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4327274 Fri, 07 Jan 2011 14:48:13 +0100 4327274 http://www.medworm.com/index.php?rid=4327275&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr818677224124662%2F Conclusions  This study demonstrates that a better functional status and absence of diabetes mellitus are associated to higher FMD regardless of the etiology of the cardiac disease. Content Type Journal ArticlePages 1-7DOI 10.1007/s00392-010-0275-yAuthors Marco Matteo Ciccone, Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Bari, ItalyMassimo Iacoviello, Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Bari, ItalyAgata Puzzovivo, Cardiovascular Diseases Section, Department of Emergency and Organ Transplantation (DETO), University of Bari, Bari, ItalyPietro Scicchitano, Cardiovascular Diseases Section, Department of Emergency and Organ Transplant... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4327275 Thu, 06 Jan 2011 17:53:08 +0100 4327275 http://www.medworm.com/index.php?rid=4319237&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc1940x5151tnq042%2F Conclusions  Our data indicate a low level of blood pressure control, especially in patients at an increased risk for cardiovascular events, such as those with diabetes or cardiovascular comorbidities. Major efforts are required to improve hypertension management as recommend by current treatment guidelines. Content Type Journal ArticleDOI 10.1007/s00392-010-0271-2Authors Martin Thoenes, Institute for Clinical Pharmacology, Medical Faculty Carl Gustav Carus, Technical University, Dresden, GermanyUlrich Tebbe, Klinikum Lippe GmbH, Fachbereich Herz-Kreislauf-Lunge-Niere, Röntgenstrasse 18, 32756 Detmold, GermanyLudger Rosin, Sanofi-Aventis, Abteilung Medizin, Berlin, GermanyW. Dieter Paar, Sanofi-Aventis, Abteilung Medizin, Berlin, GermanyPeter Bramlage, Institute for... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4319237 Tue, 04 Jan 2011 17:50:55 +0100 4319237 http://www.medworm.com/index.php?rid=4319238&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3706146105456xur%2F Conclusion  We have demonstrated for the first time increased Lp-PLA2 level in patients with isolated CAE, suggesting that Lp-PLA2 may be involved in the pathogenesis of CAE. Content Type Journal ArticleDOI 10.1007/s00392-010-0274-zAuthors Levent Korkmaz, Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, TurkeyEmre Erkuş, Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, TurkeyAbdulkadir Kırış, Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trabzon, TurkeyMustafa Tarık Ağaç, Department of Cardiology, Ahi Evren Cardiovascular and Thoracic Surgery Training and Research Hospital, Trab... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4319238 Tue, 04 Jan 2011 17:50:52 +0100 4319238 http://www.medworm.com/index.php?rid=4319239&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff3tr817377085322%2F Conclusion  Both single time point cTnT concentrations and CK activities correlate well with infarct size early after primary PCI for STEMI. Cardiac TnT levels determined 3–4 days after revascularization for acute myocardial infarction allow for a good estimation of acute infarct size as well as an approximation of LV function and morphology. Content Type Journal ArticleDOI 10.1007/s00392-010-0273-0Authors Gert Klug, University Clinic of Internal Medicine III, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, AustriaAgnes Mayr, University Clinic of Internal Medicine III, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, AustriaJohannes Mair, University Clinic of Internal Medicine III, Medical University Innsbruck, Anichstrasse 35, 602... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4319239 Tue, 04 Jan 2011 07:39:18 +0100 4319239 http://www.medworm.com/index.php?rid=4303212&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8046670746537173%2F Conclusions  Addition of levosimendan to conventional therapy did not improve outcome in patients with PPCM. In patients with PLVD or patients who died, LVEF, LVESD and left atrial diameter were worse than those with complete resolution. Content Type Journal ArticleDOI 10.1007/s00392-010-0279-7Authors Murat Biteker, Department of Cardiology, Haydarpaşa Numune Education and Research Hospital, Bankalar Caddesi, Horoz Apt, 4/5, Cevizli/Kartal, Istanbul, TurkeyNilüfer Ekşi Duran, Department of Cardiology, Kosuyolu Kartal Heart Education and Research Hospital, Istanbul, TurkeyHasan Kaya, Department of Cardiology, Kosuyolu Kartal Heart Education and Research Hospital, Istanbul, TurkeySabahattin Gündüz, Department of Cardiology, Kosuyolu Kartal Heart Education and Resea... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4303212 Fri, 31 Dec 2010 18:00:38 +0100 4303212 http://www.medworm.com/index.php?rid=4303213&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq583245615554714%2F Abstract  The purpose of the study was an assessment of left ventricular diastolic function in children after the successful repair of aortic coarctation (CoA). The prospective study concerned 32 pediatric patients after the CoA surgery. Tissue Doppler imaging parameters including strain and strain rate and the conventional echocardiographic indexes were analyzed in patients and healthy controls. Analysis of mitral annulus velocities, E–E′ ratio, strain, and strain rate of left ventricular mid-cavity segments and conventional indexes of mitral inflow showed the worsening of left ventricular diastolic mechanics in the study group compared to healthy controls. The E/E′ ratio was significantly higher in the study group compared to the control group (8.30 ± 3.24 ... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4303213 Fri, 31 Dec 2010 06:44:57 +0100 4303213 http://www.medworm.com/index.php?rid=4289149&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff51136m511672602%2F This article gives an overview on the late-breaking clinical trials in the field of cardiovascular medicine which were presented during the hotline sessions at the American Heart Association Congress, held in Chicago, USA, from 13 to 17th November 2010. The data have been presented by leading experts in the field with relevant positions in the trials. The summaries provided in the manuscript were generated from the oral presentations and the webcasts of the American Heart Association (Laufs in Clin Res Cardiol 97:1–11, 2008; Möllmann in Clin Res Cardiol 98:1–7, 2009). The following papers are discussed in alphabetical order: ACT, ADVANCE, ASCEND-HF, ASCOT-CRP, CLOSURE I, DEFINE, EMPHASIS-HF, GRAVITAS, P-OM3, RAFT, ROCKET-AF, SMART-AV, SYMPLICITY HTN-2, TELE-HF, TIM-HF. Conte... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4289149 Wed, 22 Dec 2010 20:13:40 +0100 4289149 http://www.medworm.com/index.php?rid=4272828&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg377g48289040515%2F Content Type Journal ArticleDOI 10.1007/s00392-010-0265-0Authors Thorsten Eichler, Department of Pediatric Cardiology and Intensive Care Medicine, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, GermanyThomas Paul, Department of Pediatric Cardiology and Intensive Care Medicine, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, GermanyHeike E. Schneider, Department of Pediatric Cardiology and Intensive Care Medicine, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37099 Göttingen, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4272828 Fri, 17 Dec 2010 06:51:39 +0100 4272828 http://www.medworm.com/index.php?rid=4272829&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0010512347539437%2F Conclusion  Based on the best available data, in patients with symptomatic severe AS, TAVI demonstrates an improved 1-year survival compared with medical treatment. The survival benefit of TV-TAVI over medical therapy elucidated from this systematic literature review is +16.8% and therefore, in good congruence with the recently published results from the randomized PARTNER US trial (+20%). Content Type Journal ArticleDOI 10.1007/s00392-010-0268-xAuthors L. Figulla, Department of Cardiology, University Hospital of Essen, Hufelandstrasse 55, 45122 Essen, GermanyA. Neumann, Institute for Health Care Management and Research, University of Duisburg-Essen, Schützenbahn 70, 45127 Essen, GermanyH. R. Figulla, Department of Cardiology, University Hospital of Jena, Erlanger A... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4272829 Fri, 17 Dec 2010 06:51:38 +0100 4272829 http://www.medworm.com/index.php?rid=4272830&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff94244k864330637%2F Conclusions  Approximately one-fourth of patients with NSTEMI revealed OCA that was more frequently found in coronary arteries supplying the infero- or posterolateral myocardium. Patients with OCA had larger infarcts and more non-fatal reinfarctions than patients with non-OCA. Well-developed collaterals may limit the myocardial damage in these patients. Content Type Journal ArticleDOI 10.1007/s00392-010-0269-9Authors Philipp Bahrmann, Department of Internal Medicine/Cardiology, University of Leipzig, Heart Center, 04289 Leipzig, GermanyJustus Rach, Department of Internal Medicine/Cardiology, University of Leipzig, Heart Center, 04289 Leipzig, GermanySteffen Desch, Department of Internal Medicine/Cardiology, University of Leipzig, Heart Center, 04289 Leipzig, GermanyG... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4272830 Fri, 17 Dec 2010 06:51:35 +0100 4272830 http://www.medworm.com/index.php?rid=4272831&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk7612u85q33616u1%2F Conclusions  Residual stenosis in AoD does not affect the arterial vasodilatation nor stiffness in patients after CoAo repair. Early operation has no impact on peripheral vascular remodeling or central pressure which supports the claim that coarctation of the aorta is a systemic vascular disorder which leads to progressive vascular and end-organ damage despite early correction. Content Type Journal ArticleDOI 10.1007/s00392-010-0263-2Authors Olga Trojnarska, 1st Department of Cardiology, Poznań University of Medical Sciences, Poland, ul. Długa 1/2, 61-848 Poznań, PolandLudwina Szczepaniak-Chicheł, Department of Hypertensiology, Angiology and Internal Medicine, Poznań University of Medical Sciences, Poznań, PolandKatarzyna Mizia-Stec, Department of Cardiology, M... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4272831 Thu, 16 Dec 2010 06:52:43 +0100 4272831 http://www.medworm.com/index.php?rid=4267300&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3rp820551l1747w5%2F Content Type Journal ArticleDOI 10.1007/s00392-010-0267-yAuthors Armin Wessel, Department of Paediatric Cardiology, Medical School Hannover, Hannover, GermanyKarsten Harms, Department of Paediatrics, Klinikum Hildesheim, Hildesheim, GermanyKambiz Norozi, Department of Paediatric Cardiology, Medical School Hannover, Hannover, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4267300 Wed, 15 Dec 2010 19:11:38 +0100 4267300 http://www.medworm.com/index.php?rid=4267301&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj8qgr4v651x32ru1%2F Content Type Journal ArticleDOI 10.1007/s00392-010-0257-0Authors Roja Soutodeh, Department I, Cardiology, Angiology, Intensive Care, Klinikum Lippe-Detmold, Roentgenstrasse 18, 32756 Detmold, GermanyJürgen Götz, Department I, Cardiology, Angiology, Intensive Care, Klinikum Lippe-Detmold, Roentgenstrasse 18, 32756 Detmold, GermanyUlrich Tebbe, Department I, Cardiology, Angiology, Intensive Care, Klinikum Lippe-Detmold, Roentgenstrasse 18, 32756 Detmold, GermanyAlessandro Cuneo, Department I, Cardiology, Angiology, Intensive Care, Klinikum Lippe-Detmold, Roentgenstrasse 18, 32756 Detmold, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4267301 Wed, 15 Dec 2010 19:11:37 +0100 4267301 http://www.medworm.com/index.php?rid=4267302&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa368l13pw7001350%2F Content Type Journal ArticleDOI 10.1007/s00392-010-0266-zAuthors Tobias Härle, Department of Cardiology, Heart Center, Klinikum Oldenburg gGmbH, Rahel-Straus-Str. 10, 26133 Oldenburg, GermanyKay Kronberg, Department of Cardiology, Heart Center, Klinikum Oldenburg gGmbH, Rahel-Straus-Str. 10, 26133 Oldenburg, GermanyHolger Nef, Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, GermanyHelge Möllmann, Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, GermanyAlbrecht Elsässer, Department of Cardiology, Heart Center, Klinikum Oldenburg gGmbH, Rahel-Straus-Str. 10, 26133 Oldenburg, Germany Journal Clinical Research in CardiologyOnline ISSN 1861-0692Print ISSN 1861-0684 (Source: Clinical Research in Cardiology) Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4267302 Wed, 15 Dec 2010 19:11:36 +0100 4267302 http://www.medworm.com/index.php?rid=4267303&cid=s_33455_7_f&fid=33455&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr0k750370706421p%2F Content Type Journal ArticleDOI 10.1007/s00392-010-0264-1Authors Michael Huntgeburth, Klinik III für Innere Medizin, Department of Cardiology, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50937 Cologne, GermanyMatthias Laudes, Klinik II und Poliklinik für Innere Medizin, Department of Endocrinology, Universität zu Köln, Kerpener Str. 62, 50937 Cologne, GermanyVolker Burst, Klinik IV für Innere Medizin, Department of Nephrology, Universität zu Köln, Kerpener Str. 62, 50937 Cologne, GermanyStefan Krämer, Medizinische Klinik, Malteserkrankenhaus St. Hildegardis, Bachemer Str. 29-33, 50931 Cologne, GermanyHannes Reuter, Klinik III für Innere Medizin, Department of Cardiology, Herzzentrum der Universität zu Köln, Kerpener Str. 62, 50937 Cologne, GermanyStephan Rosenkr... Clinical Research in Cardiology journals http://www.medworm.com/rss/comments.php?id=4267303 Wed, 15 Dec 2010 19:11:35 +0100 4267303