Contact Dermatitis via MedWorm.com

Dermatitis from common ivy (Hedera helix L. subsp. helix) in Europe: past, present, and future

Contact Dermatitis — Sat, 06 Mar 2010 00:00:00 +0100

The objective of the article is to present the results of aimed patch testing with the main common ivy allergen, falcarinol, during a 16-year period and review the newer literature. Consecutive patients tested with falcarinol 0.03% petrolatum from May 1993 to May 2009 were included. Cases published since 1987 were retrieved from the PubMed database. One hundred and twenty-seven Danish patients were tested with falcarinol and 10 (7.9%) tested positive. Seven were occupationally sensitized. Between 1994 and 2009, 28 new cases of contact dermatitis from ivy were reported, 2 of which were occupational. Only 11 of the 28 patients were tested with pure allergens. Falcarinol is not only widely distributed in the ivy family, but also in the closely related Apiaceae. Sensitization may occur in chil...

Formaldehyde-releasers: relationship to formaldehyde contact allergy. Part 2. Formaldehyde-releasers in clothes: durable press chemical finishes

Contact Dermatitis — Thu, 04 Mar 2010 00:00:00 +0100

This is the second part of a review article on formaldehyde-releasers used as durable press chemical finishes (DPCF) in textiles. The early finishes contained large amounts of free formaldehyde, which led to many cases of allergic contact dermatitis to clothes in the 1950s and 1960s. Currently, most finishes are based on modified dimethylol dihydroxyethyleneurea, which releases less formaldehyde. Nevertheless, recent studies in the United States and Israel have identified patients reacting to DPCF, considered to have allergic contact reactions to clothes, either from formaldehyde released by the DPCF therein or from the DPCF per se (in patients negative to formaldehyde). However, all studies had some weaknesses in design or interpretation and in not a single case has the clinical relevance...

Formaldehyde-releasers in cosmetics in the USA and in Europe

Contact Dermatitis — Wed, 03 Mar 2010 00:00:00 +0100

Conclusions: The percentages of stay-on skin care products containing a formaldehyde-releaser are virtually identical in the USA (FDA data) and our local drugstore sample. However, this does not necessarily imply that cosmetics play no part in the differences in formaldehyde sensitization rates. (Source: Contact Dermatitis)

Assessment of nickel release from earrings randomly purchased in China and Thailand using the dimethylglyoxime test

Contact Dermatitis — Wed, 03 Mar 2010 00:00:00 +0100

Discussion: Excessive nickel release was frequent. This may contribute to the high prevalence of nickel allergy in both countries. Increased public education together with the adoption of a regulatory intervention in Thailand may be warranted. In China, enforcement of the 2002 Chinese National Standard GB 11887 may assist in reducing sensitization. These initiatives may eventually result in decreased morbidity among the Chinese and Thai citizens, but can potentially benefit recipient countries of these important earring producing countries. (Source: Contact Dermatitis)

History of international societies of contact dermatitis

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

(Source: Contact Dermatitis)

Unusual allergic contact dermatitis produced by a transcutaneous electrical nerve stimulator

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

(Source: Contact Dermatitis)

Transient localized hypertrichosis on a temporary henna tattoo

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

(Source: Contact Dermatitis)

Occupational sensitization from the Tradescantia albiflora cultivar 'Pink Joy'

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

(Source: Contact Dermatitis)

Contact dermatitis from Welsh poppy [Meconopsis cambrica (L.) Vig.]

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

(Source: Contact Dermatitis)

Systemic allergic dermatitis from chromium in a multivitamin/multimineral tablet

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

(Source: Contact Dermatitis)

Filaggrin haploinsufficiency among patients with dermatitis from a tertiary referral centre: early findings and possible phenotype

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

(Source: Contact Dermatitis)

Hairdressers with dermatitis should always be patch tested regardless of atopy status

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

Conclusions: We present findings from the largest cohort of hairdressers patch tested from a single centre. It is necessary to patch test hairdressers with dermatitis, regardless of a history of atopy. Strategies to reduce prevalence of allergic contact dermatitis are required. (Source: Contact Dermatitis)

Lifestyle factors and hand eczema in a Swedish adolescent population

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

Conclusions: The studied lifestyle practices were more prevalent in girls. Smoking, tattooing, and diet were not associated with the occurrence of hand eczema. (Source: Contact Dermatitis)

Patch testing in patients treated with systemic immunosuppression and cytokine inhibitors

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

Conclusions: Positive patch test reactions can be elicited in patients taking azathioprine, ciclosporin, infliximab, adalimumab, etanercept, methotrexate, mycophenolate mofetil, and tacrolimus. However, it remains unclear what effect these immunosuppressive drugs may have on suppressing allergic patch test reactions and further studies should be carried out to determine the reliability of testing in these circumstances. (Source: Contact Dermatitis)

Interlaboratory studies with a proposed patch test design to evaluate the irritation potential of surfactants

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

Conclusions: Use of the standardized protocol and training of assessors improved the reliability and consistency of results whereby the irritation potentials of the references and test samples were ranked similarly by the laboratories. (Source: Contact Dermatitis)

Measurement of a possible patch-testing outcome indicator

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

Conclusions: The ratio of relevantly patch-test-positive patients resolved/improved after allergen avoidance is a useful patch-testing outcome indicator. (Source: Contact Dermatitis)

Sensitive skin: closing in on a physiological cause

Contact Dermatitis — Tue, 23 Feb 2010 00:00:00 +0100

The phenomenon of 'sensitive skin' is a relatively recent complaint in which certain individuals report more intense and frequent adverse sensory effects than the normal population upon use of cosmetic (personal-care) products. Originally defined as a minority complaint, sensitive skin is now claimed by a majority of women in industrialized countries and nearly half of men. Sensitive skin is self-diagnosed and typically unaccompanied by any obvious physical signs of irritation, and the number of individuals who claim sensitivity has risen steadily with the number of consumer products targeted towards this supposedly uncommon group. Believed by many dermatologists, therefore, to be a 'princess and the pea' phenomenon, the problem of sensitive skin has largely avoided focussed research. Over...

The association between hand eczema and nickel allergy has weakened among young women in the general population following the Danish nickel regulation: results from two cross-sectional studies

Contact Dermatitis — Tue, 06 Oct 2009 23:00:00 +0100

Conclusions: Regulatory control of nickel exposure may have reduced the effect of nickel on hand eczema in the young female population. (Source: Contact Dermatitis)

Does allergic contact dermatitis from formaldehyde in clothes treated with durable-press chemical finishes exist in the USA?

Contact Dermatitis — Mon, 05 Oct 2009 23:00:00 +0100

The objectives of this review are (i) to investigate whether clothes sold in the USA may contain enough free formaldehyde to elicit ACD in previously sensitized individuals and (ii) to assess the validity of US reports on ACD from formaldehyde in DPCF treated clothes. Literature was examined using various resources. The threshold level for formaldehyde in clothes that may cause ACD in sensitized individuals is unknown; we present data suggesting that levels < 200 ppm will be safe for most patients and that textiles will rarely contain higher amounts. All US studies presenting patients with ACD from formaldehyde in clothes had some weaknesses and in no report was the diagnosis proven beyond doubt. Currently, there is no definite proof that textile ACD from formaldehyde in DPCF in the USA ex...

Reactions to resin-based dental materials in patients–type, time to onset, duration, and consequence of the reaction

Contact Dermatitis — Mon, 05 Oct 2009 23:00:00 +0100

Conclusion: Immediate reactions to resin-based materials were more prevalent than delayed allergic reactions, and the mechanism of the immediate reactions is probably non-allergic in most cases. There is a need for developing provocation tests to verify the association between the reaction and the material, and also to identify the offending component. (Source: Contact Dermatitis)

The possible relevance of sex hormones on irritant and allergic responses: their importance for skin testing

Contact Dermatitis — Mon, 05 Oct 2009 23:00:00 +0100

Dermatological responses are affected by the menstrual cycle phase in female patients, an unsurprising observation as oestrogen and progesterone affect the skin and immunological function, with oestrogen suppression of cellular immunity in particular. Exacerbation of dermatological symptoms is typically observed in either the latter phase of the menstrual cycle or during menstruation. The allergic response is diminished in the ovulatory phase and heightened in the progestinic phase. Definitive conclusions with regard to the effect of reproductive hormones on skin disorders have been somewhat hampered by a body of research that has employed diverse research parameters, such as dosage, testing sites, concentration, vehicle of irritant delivery, and method of assessment, however, individual p...

Contact urticaria and asthma from Sarcophaga carnaria

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact dermatitis from incense

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact dermatitis to 1,2-benzisothiazolin-3-one in the water softener manufacturing industry

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Irritant contact dermatitis from shower cream applied as a moisturizing cream: a review of three cases*

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Systemic allergic dermatitis reaction to nickel released from an eyelet in an intravenous catheter

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact dermatitis to ethylhexylglycerin and pentylene glycol

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Erythema multiforme-like generalized contact dermatitis to l-menthol contained in anti-inflammatory medical compresses as an ingredient

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Contact dermatitis to captopril

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Occupational contact urticaria caused by donepezil

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Delayed hypersensitivity to corticosteroids in a series of 315 patients: clinical data and patch test results

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

Conclusion: A prevalence of corticosteroid allergy of 2.7% was found. Despite validity of the ABCD (sub)classification in many cases, possible adjustments may have to be considered. (Source: Contact Dermatitis)

Quantitative patch and repeated open application testing in hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitive-patients

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

Objective: To identify the concentration of the fragrance compound hydroxyisohexyl 3-cyclohexene carboxaldehyde (INCI) (HICC) that is sufficiently low not to cause an allergic reaction in patients with proven sensitization.Methods: Repeated open application testing (ROAT) in 64 subjects with 2 preparations (perfume and cream) in different concentration (0.005[ndash]2.5%). Confirmatory patch testing with four preparations in two different concentrations (2.5% and 5%).Results: The concentrations of HICC being tolerated by 90% of those sensitized to HICC are estimated as (Source: Contact Dermatitis)

Health-related quality of life in health care workers with work-related skin diseases

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

Conclusions: Although HCWs with suspected OSD display considerable HRQoL impairments, (general) PF and general health perception appear less affected than expected. Severity appears to affect specific and to a lesser extent general HRQoL. Clinical and demographic variables contributed moderately to the prediction of specific and little to the prediction of general HRQoL. (Source: Contact Dermatitis)

Usefulness of skin testing in cutaneous drug eruptions in routine practice

Contact Dermatitis — Tue, 22 Sep 2009 23:00:00 +0100

Conclusions: Drug skin testing appeared useful in investigating cutaneous drug eruptions in routine practice, including not only drugs with a high imputation score (I3) but also those with a lower score (I1, I2). Drug skin testing should lead to oral rechallenge of drugs with negative tests in order to determine which drugs may be used safely. (Source: Contact Dermatitis)

A review of the materials and allergens in protective gloves

Contact Dermatitis — Mon, 31 Aug 2009 23:00:00 +0100

The ingredients previously reported to cause protective glove allergy are presented and evaluated for strength of evidence. Allergens that have caused both delayed hypersensitivity and contact urticaria are considered for rubber, plastic, leather, and textile gloves. The current guidelines regarding glove manufacture are described. A list of materials confirmed by the industry to be used in glove production is presented together with a suggested series for investigating patients with delayed type hypersensitivity and contact urticaria secondary to glove use. (Source: Contact Dermatitis)

Occupational contact dermatitis due to multiple sensitizations in a pig farmer

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact cermatitis to retapamulin ointment

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Contact allergy to tetrasodium EDTA in a sunscreen

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Chronic recurrent otitis externa secondary to allergic contact dermatitis to nickel and phosphorus sesquisulfide

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Occupational allergic contact dermatitis associated with dimethyl fumarate in clothing

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

A rare case of allergic contact dermatitis from silver nitrate in a widely used special patch test marker

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic and photoallergic contact dermartitis from etofenamate: study of 14 cases

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Acrylate-induced hand dermatitis in the manufacture of contact lenses

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Principles and methodology for translation and cross-cultural adaptation of the Nordic Occupational Skin Questionnaire (NOSQ-2002) to Spanish and Catalan

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

Conclusions: The final versions of the Spanish and Catalan NOSQ-2002 questionnaires are now available at www.NRCWE.dk/NOSQ. (Source: Contact Dermatitis)

Allergens associated with severe symptoms of hand eczema and a poor prognosis

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

Conclusions: Nickel, chromate, formaldehyde, methyldibromo glutaronitrile and sesquiterpene lactone mix were allergens associated with the greatest severity of hand eczema. Patients with chromate allergy had the worst prognosis. (Source: Contact Dermatitis)

Accumulation of FITC near stratum corneum–visualizing epidermal distribution of a strong sensitizer using two-photon microscopy

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

Conclusions: TPM, which has never been used in this context before, is a promising tool for visualizing the distribution of fluorescent compounds of varying reactivity in intact skin. The strong allergen FITC is mainly retained in or adjacent to SC, whereas most fluorescein diffused through the epidermis. (Source: Contact Dermatitis)

Interleukin-1 receptor antagonist and tumour necrosis factor-alpha gene polymorphisms in Turkish patients with allergic contact dermatitis

Contact Dermatitis — Thu, 20 Aug 2009 23:00:00 +0100

Conclusions: Our findings suggest that TNF[alpha] (G/G) gene polymorphism may play role in susceptibility to allergic contact dermatitis in Turkish patients. (Source: Contact Dermatitis)

Formaldehyde-releasers: relationship to formaldehyde contact allergy. Contact allergy to formaldehyde and inventory of formaldehyde-releasers

Contact Dermatitis — Fri, 31 Jul 2009 23:00:00 +0100

This is one of series of review articles on formaldehyde and formaldehyde-releasers (others: formaldehyde in cosmetics, in clothes and in metalworking fluids and miscellaneous). Thirty-five chemicals were identified as being formaldehyde-releasers. Although a further seven are listed in the literature as formaldehyde-releasers, data are inadequate to consider them as such beyond doubt. Several (nomenclature) mistakes and outdated information are discussed. Formaldehyde and formaldehyde allergy are reviewed: applications, exposure scenarios, legislation, patch testing problems, frequency of sensitization, relevance of positive patch test reactions, clinical pattern of allergic contact dermatitis from formaldehyde, prognosis, threshold for elicitation of allergic contact dermatitis, analytic...

Botanical Dermatology Course & Workshop

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Creating an electronic collaboration between international contact dermatitis groups

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Sodium metabisulfite – a contact allergen?

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Mobile phones are now covered by the European Union Nickel Directive

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

No cross-reactions between tetrazepam and other benzodiazepines: a possible chemical explanation

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact dermatitis from dibucaine hydrochloride, chlorpheniramine maleate, and naphazoline hydrochloride in an over-the-counter topical antiseptic

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Occupational airborne contact dermatitis to simvastatin, carvedilol, and zolpidem

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Flare-up of patch test of trimethoprim–sulfamethoxazole (co-trimoxazole) during oral desensitization

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Occupational allergic contact dermatitis to hydroxyethyl methacrylate (2-HEMA) in a manicurist

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact dermatitis to ethylene oxide

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Age- and sex-related variations in allergic contact dermatitis to common allergens

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Measurement of patient-relevant benefits in the treatment of chronic hand eczema – a novel approach

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

Conclusions: The PBI-HE is a feasible, reliable, and valid instrument for the assessment of patient-relevant treatment benefits in CHE. (Source: Contact Dermatitis)

The European baseline series in 10 European Countries, 2005/2006 – Results of the European Surveillance System on Contact Allergies (ESSCA)

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

Conclusions: Notwithstanding residual methodological variation (affecting at least some 'difficult' allergens) tackled by ongoing efforts for standardization, a comparative analysis as presented provides (i) a broad overview on contact allergy frequencies and (ii) interesting starting points for further, in-depth investigation. (Source: Contact Dermatitis)

Characterization of the polysensitized patient: a matched case–control study

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

Conclusion: Patients with atopic eczema were overrepresented in the group of polysensitized patients and polysensitized patients should be viewed in the light of occurrence or lack of atopic eczema. (Source: Contact Dermatitis)

Contact allergy to epoxy (meth)acrylates

Contact Dermatitis — Wed, 15 Jul 2009 23:00:00 +0100

Conclusions: The great majority of allergic patch test reactions to bis-GMA, bis-GA, GMA and bis-EMA were not associated with specific exposure, and cross-allergy to DGEBA epoxy resin remained a probable explanation. However, independent reactions to bis-GA indicated specific exposure. Anaerobic sealants may induce sensitization not only to aliphatic (meth)acrylates but also to aromatic bis-GA. (Source: Contact Dermatitis)

Patients with airborne sensitization/contact dermatitis from budesonide-containing aerosols 'by proxy'

Contact Dermatitis — Tue, 30 Jun 2009 23:00:00 +0100

Conclusion: Air exposure to inhalation corticosteroids used 'by proxy' and to budesonide, in particular, needs to be taken into account as a potential cause of primary sensitization and/or airborne allergic contact dermatitis, sometimes also in an occupational context. (Source: Contact Dermatitis)

Allergic contact dermatitis from fragrance components in specific topical pharmaceutical products in Belgium

Contact Dermatitis — Sun, 31 May 2009 23:00:00 +0100

Conclusions: Fragrances, the presence of which is in most cases unnecessary, do contribute to iatrogenic allergic contact dermatitis. Moreover, sensitized patients have difficulties in avoiding their specific allergens because standardized labelling of the ingredients in pharmaceutical products is lacking. (Source: Contact Dermatitis)

Standardization in Contact Dermatitis – a highly desirable aim

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact dermatitis caused by tribenoside

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Allergic contact dermatitis to povidone–iodine

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Contact sensitization to topical diltiazem

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Three cases of allergic contact dermatitis to 4,4'-diaminodiphenylmethane

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Recurrent cyclic hyperkeratotic eczema after occupational alkali burn: traumatic chronic irritant dermatitis

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

A case of allergic contact dermatitis caused by glucan oligosaccharide

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Nail dystrophy and fingertip dermatitis as a manifestation of methyl methacrylate allergic contact dermatitis in a cow hoof trimmer

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

(Source: Contact Dermatitis)

Investigation of contact allergy to dental metals in 206 patients

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

Conclusions: Clinically relevant contact allergies to dental metals are infrequent. Gold sodium thiosulfate and palladium chloride presented the most frequent contact allergens. (Source: Contact Dermatitis)

Hand dermatitis among veterinarians from Queensland, Australia

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

Conclusions: Overall, this study suggests that HD may be more prevalent among veterinarians in Queensland than among their counterparts studied elsewhere. Veterinary practices may need to consider making non-latex gloves available or avoiding latex products wherever possible, particularly for their female staff. The importance of HD to the veterinary profession is predicted to increase as females begin to make up a greater proportion of registered veterinarians as result of a demographic shift. (Source: Contact Dermatitis)

Epidemiology of jellyfish stings reported to summer health centres in the Salento peninsula (Italy)

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

Conclusion: In the light of the significant level of medical assistance provided, there is a need to identify suitable strategies that will guarantee the best response in terms of both prevention and treatment. (Source: Contact Dermatitis)

Photopatch testing with an extended series of photoallergens: a 5-year study

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

Conclusions: Our results are discordant with most recently published studies because of the particularities of the population studied and to regional prescribing habits. Therefore, apart from the recommended baseline series of photoallergens, other substances must be tested according to regional peculiarities. (Source: Contact Dermatitis)

Frequency of sensitization to methyl aminolaevulinate after photodynamic therapy

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

Conclusions: This study demonstrates a considerable risk of sensitization after Metvix-PDT. We suggest that the patients are interviewed to detect late or persistent local reactions after PDT. These reactions are often considered to be local infections but may represent allergic contact dermatitis, and therefore, patients should be offered patch testing with Metvix® cream. (Source: Contact Dermatitis)

p-Phenylenediamine sensitization is more prevalent in central and southern European patch test centres than in Scandinavian: results from a multicentre study

Contact Dermatitis — Mon, 25 May 2009 23:00:00 +0100

Conclusions: PPD sensitization caused by exposure to hair dyes is frequent and remains a present problem for patients visiting contact dermatitis clinics, especially in patch test centres located in Central and Southern Europe. (Source: Contact Dermatitis)

Expression of surface markers on the human monocytic leukaemia cell line, THP-1, as indicators for the sensitizing potential of chemicals.