MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Current Pain and Headache Reports' source. Sat, 20 Mar 2010 14:40:55 +0100 http://www.medworm.com/index.php?rid=3372083&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdq1p735746813468%2F Abstract  Cluster headache (CH) is a neurovascular headache syndrome characterized by headache attacks that occur with a circadian and circannual periodicity. The calculated prevalence of CH in reproductive-aged women is 7.5 of 100,000 women. Although data suggest that CH during pregnancy is a relatively rare condition, when it does occur, attacks remain unchanged in character and severity in the majority of patients. Thus, treatment of CH in pregnant and lactating women may remain a significant therapeutic challenge. This manuscript briefly reviews the epidemiology of CH in women, and then focuses on treatment options for both acute and preventative management of CH in pregnant and lactating women. Content Type Journal ArticleDOI 10.1007/s11916-010-0102-1Authors Anne... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3372083 Mon, 15 Mar 2010 05:32:12 +0100 3372083 http://www.medworm.com/index.php?rid=3356476&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2143515j87681446%2F Abstract  Periods of deliberate fasting with restriction to intake of solid food are practiced worldwide, mostly based on a traditional, cultural, or religious background. Recent evidence from clinical trials shows that medically supervised modified fasting (200–500 kcal nutritional intake/day) with periods from 7 to 21 days is efficacious in the treatment of rheumatic diseases and chronic pain syndromes. Here, fasting is frequently accompanied by increased alertness and mood enhancement. The beneficial claims of fasting are supported by experimental research, which has found fasting to be associated with increased brain availability of serotonin, endogenous opioids, and endocannabinoids. Fasting-induced neuroendocrine activation and mild cellular stress response... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3356476 Wed, 10 Mar 2010 16:14:10 +0100 3356476 http://www.medworm.com/index.php?rid=3336955&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3063604q571q3t73%2F Abstract  Torture is widely practiced throughout the world. Recent studies indicate that 50% of all countries, including 79% of the G-20 countries, continue to practice systematic torture despite a universal ban. It is well known that torture has numerous physical, psychological, and pain-related sequelae that can inflict a devastating and enduring burden on its victims. Health care professionals, particularly those who specialize in the treatment of chronic pain, have an obligation to better understand the physical and psychological effects of torture. This review highlights the epidemiology, classification, pain sequelae, and clinical treatment guidelines of torture victims. In addition, the role of pharmacologic and psychologic interventions is explored in the context of... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3336955 Wed, 03 Mar 2010 08:07:53 +0100 3336955 http://www.medworm.com/index.php?rid=3336954&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb162g17115682j5j%2F This article summarizes current understanding of the role of pain-related fear in the onset of acute pain incidents, the transition of acute pain to chronic, and the pain severity and disability of patients with ongoing chronic pain conditions. Treatments demonstrated to reduce pain-related fear are presented, evidence demonstrating their efficacy at reducing disability and pain severity are summarized, and recent criticisms of the fear-avoidance model and future directions are considered. Content Type Journal ArticleDOI 10.1007/s11916-010-0094-xAuthors Dennis C. Turk, University of Washington Department of Anesthesiology & Pain Medicine Box 356540 Seattle WA 98195 USAHilary D. Wilson, University of Washington Department of Anesthesiology & Pain Medicine Box 356540 Seattle WA 98... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3336954 Wed, 03 Mar 2010 08:07:53 +0100 3336954 http://www.medworm.com/index.php?rid=3328999&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr8476614p7l54u24%2F Abstract  Chronic pain is an affliction that affects a large proportion of the general population and is often accompanied by a myriad of negative emotional, cognitive, and physical effects. However, current pain adaptation paradigms do not account for the many chronic pain patients who demonstrate little or no noticeable impairment due to the effects of chronic pain. This paper offers resilience as an integrative perspective that can illuminate the traits and mechanisms underlying the sustainability of a good life and recovery from distress for individuals with chronic pain. Content Type Journal ArticleDOI 10.1007/s11916-010-0095-9Authors John A. Sturgeon, Arizona State University Psychology Department 950 South McAllister Tempe AZ 85287-1104 USAAlex J. Zautra, Arizon... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3328999 Tue, 02 Mar 2010 10:07:52 +0100 3328999 http://www.medworm.com/index.php?rid=3329000&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F946r6624222ph87r%2F Abstract  Lidocaine and mexiletine are class 1B antiarrhythmic drugs that act on sodium channels. Lidocaine is also an important anesthetic and topical agent that is useful in the treatment of multiple pain disorders, and mexiletine is commonly used for neuropathic pain and myotonia. Both intravenous lidocaine and mexiletine are increasingly used to treat pain syndromes and appear to be particularly effective in neuropathic pain. This suggests a role for these agents in patients with headache disorders. This article describes the role of intravenous lidocaine and mexiletine in the management of headache and trigeminal autonomic cephalalgias based on the published literature to date and provides practical guidelines for their use. Content Type Journal ArticleDOI 10.1007/... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3329000 Tue, 02 Mar 2010 10:07:51 +0100 3329000 http://www.medworm.com/index.php?rid=3329001&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8674313365558411%2F Abstract  Cluster headache is a primary neurovascular headache. It is a strictly unilateral head pain that is associated with cranial autonomic symptoms and usually follows circadian and circannual patterns. Chronic cluster headache, which accounts for about 10% to 15% of patients with cluster headache, lacks the circadian pattern and is often resistant to pharmacological management. The sphenopalatine ganglion (SPG), located in the pterygopalatine fossa, is involved in the pathophysiology of cluster headache and has been a target for blocks and other surgical approaches. Percutaneous radiofrequency ablation of the SPG was shown to have encouraging results in those patients with intractable cluster headaches. Content Type Journal ArticleDOI 10.1007/s11916-010-0100-3Auth... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3329001 Tue, 02 Mar 2010 10:07:49 +0100 3329001 http://www.medworm.com/index.php?rid=3315611&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp545l34w58216299%2F Abstract  Cluster headache (CH) is a rare, excruciating primary headache disorder. A genetic basis has been suggested by family and twin studies, but the mode of transmission seems to vary and the amount of heritability is unclear. The number of genetic association studies investigating variants implicated in the pathophysiology of CH is limited. The HCRTR2 1246G > A and the ADH4 925A > G polymorphisms have been associated with CH. The former has been confirmed and may affect the hypothalamic hypocretin system. However, it only appears to account for a part of the genetic susceptibility for CH, and additional genetic and environmental factors are likely implicated. Pharmacogenetic studies have suggested that the GNB3 825C > T polymorphism may modify treat... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3315611 Thu, 25 Feb 2010 17:58:50 +0100 3315611 http://www.medworm.com/index.php?rid=3315612&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe0u6240238222827%2F Abstract  In humans, the experience of pain and suffering is conveyed specifically by language. Noninvasive neuroimaging techniques now provide an account of neural activity in the human brain when pain is experienced. Knowledge gleaned from neuroimaging experiments has shaped contemporaneous accounts of pain. Within the biopsychosocial framework, nociception is undoubtedly required for survival, but is neither necessary nor sufficient for the consciousness of pain in humans. Pain emerges from the brain, which also exerts a top-down influence on nociception. In the brains of patients with chronic pain, neuroimaging has revealed subtle but significant structural, functional, and neurochemical abnormalities. Converging evidence suggests that the chronic pain state may arise f... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3315612 Thu, 25 Feb 2010 17:58:45 +0100 3315612 http://www.medworm.com/index.php?rid=3313247&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F58422j541j243317%2F Abstract  Opioids have played a critical role in achieving pain relief in both modern and ancient medicine. Yet, their clinical use can be limited secondary to unwanted side effects such as tolerance, dependence, reward, and behavioral changes. Identification of glial-mediated mechanisms inducing opioid side effects include cytokine receptors, κ-opioid receptors, N-methyl-D-aspartate receptors, and the recently elucidated Toll-like receptors. Newer agents targeting these receptors such as AV411, MK-801, AV333, and SLC022, and older agents used outside the United States or for other disease conditions, such as minocycline, pentoxifylline, and UV50488H, all show varied but promising profiles for providing significant relief from opioid side effects, while simultaneously poten... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3313247 Thu, 25 Feb 2010 08:02:32 +0100 3313247 http://www.medworm.com/index.php?rid=3309023&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn61j30005j2g1610%2F Abstract  Cutaneous allodynia (CA), the perception of pain when a non-noxious stimulus is applied to normal skin, has been described in various pain syndromes. The pathophysiology of CA in headache is thought to be related to central sensitization of brainstem, and possibly thalamic, neurons. The recognition of CA in cluster headache (CH) is recent, and available data are scant. Some studies suggest the occurrence of CA in a significant proportion of CH patients. However, one study that examined sensory thresholds in CH failed to confirm this. CA in CH is characterized by rapid onset and termination, suggesting different mechanisms compared with CA in migraine. CA in CH is common in trigeminal areas but may spread to cervical dermatomes and beyond. The relations between the... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3309023 Wed, 24 Feb 2010 06:55:47 +0100 3309023 http://www.medworm.com/index.php?rid=3304467&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy63k277771ux2775%2F Abstract  Functional and structural neuroimaging studies have provided pivotal insights into the pathophysiology of trigeminal autonomic cephalalgias (TACs), particularly cluster headache (CH). Functional imaging studies using positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) in TACs have reported activation of the posterior hypothalamus. A structural neuroimaging study using voxel-based morphometry in CH reported increased volume of the hypothalamic gray, although another larger study failed to reproduce this finding. These studies in CH prompted the use of stereotactic stimulation of the target point identified by functional and structural neuroimaging. The precise anatomical localization of the deep brain stimulation (DBS) target places ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3304467 Tue, 23 Feb 2010 08:07:03 +0100 3304467 http://www.medworm.com/index.php?rid=3247996&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn8620311875r421t%2F Abstract  Health care professionals caring for neonates (birth to 28 days of life) and infants up to 1 year of age have a professional and ethical responsibility to provide safe and effective pain management during painful procedures. Despite 14 years of research reports highlighting that sick infants are exposed to large numbers of painful procedures with minimal or no provision of pain management strategies, and generation of abundant evidence to support effectiveness of pain reduction strategies, insufficient practice changes have been made. As untreated pain in infancy has both immediate and longer-term negative consequences, such as increased sensitivity and responses to subsequent pain, it is imperative that widespread sustained practice changes are mad... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3247996 Thu, 04 Feb 2010 07:01:27 +0100 3247996 http://www.medworm.com/index.php?rid=3224129&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm8g2319512784624%2F This article reviews the literature on the importance of psychological issues in headache management and provides suggestions for how to address behavioral and cognitive factors and their potential for improved headache care. Content Type Journal ArticleDOI 10.1007/s11916-009-0087-9Authors Robert A. Nicholson, Saint Louis University School of Medicine Department of Neurology & Psychiatry Monteleone Hall, 1438 S. Grand Blvd. St. Louis MO 63104 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3224129 Wed, 27 Jan 2010 20:01:18 +0100 3224129 http://www.medworm.com/index.php?rid=3191272&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx6h876463209916n%2F This article reviews common ocular and neuro-ophthalmic conditions that are accompanied by pain in or near the eye. Content Type Journal ArticleDOI 10.1007/s11916-009-0088-8Authors Deborah I. Friedman, University of Rochester School of Medicine and Dentistry Flaum Eye Institute 601 Elmwood Avenue Box 659 Rochester NY 14642 USALynn K. Gordon, University of California Jules Stein Eye Institute, David Geffen School of Medicine 100 Stein Plaza Los Angeles CA 90095-7005 USAPeter A. Quiros, University of Southern California Doheny Eye Institute, Keck School of Medicine 1450 San Pablo Street, Suite 5803 Los Angeles CA 90033 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3191272 Mon, 18 Jan 2010 18:25:18 +0100 3191272 http://www.medworm.com/index.php?rid=3191273&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Feg548u411p83xv61%2F Abstract  The current conflicts in Afghanistan (Operation Enduring Freedom; commenced October 2001) and Iraq (Operation Iraqi Freedom; commenced March 2003) have been remarkable due to the more than 90% survival rate among wounded warriors. Although this statistic is a historic achievement by the military’s medical services, other medical issues have taken on greater emphasis as more casualties from war survive than ever before. Pain management of United States wounded, in particular, has been a medical issue of increasing importance, as modern understanding of the detrimental effects of pain on recovery and rehabilitation becomes clearer. In this review, a warrior’s perspective of military pain management is explored and potential for improvement discussed. Content ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3191273 Mon, 18 Jan 2010 18:25:16 +0100 3191273 http://www.medworm.com/index.php?rid=3191274&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fwr7514424722q00v%2F This article reviews recent literature in the global treatment of CPP, including pharmacologic, psychotherapy, and neuroablative, as well as specific interventions for endometriosis, interstitial cystitis, pelvic adhesive disease, adenomyosis, and pelvic venous congestion. Content Type Journal ArticleDOI 10.1007/s11916-009-0089-7Authors Isabel C. Green, Johns Hopkins University Gynecologic Specialities, Department of Gynecology and Obstetrics 600 North Wolfe Street, Phipps 249 Baltimore MD 21287 USASarah L. Cohen, Johns Hopkins University Department of Gynecology and Obstetrics 600 North Wolfe Street, Phipps 279 Baltimore MD 21287 USADayna Finkenzeller, Johns Hopkins Bayview Medical Center Department of Obstetrics and Gynecology 4940 Eastern Avenue, Room 121 Baltimore MD 21224 USAPa... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3191274 Mon, 18 Jan 2010 18:25:15 +0100 3191274 http://www.medworm.com/index.php?rid=3191275&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcmr87q6255258434%2F Abstract  Pain sensitivity is an adaptive process affected by expectation, mood, coping, operant conditioning, and the preconscious allocation of attention. Underlying mechanisms may include encoding of similar experiences (eg, depression, loss, pain-distress) in overlapping patterns of activation, failure of common regulatory mechanisms, direct top-down activation of the pain matrix, and changes in descending pain facilitatory and inhibitory tone. In theory, the combination of glial cell activation from psychological stress and neural firing from nociceptive input may be particularly likely to lead to pain sensitization and long-term structural changes in pain processing regions of the brain. In these ways, headaches in which chronicity, diffuseness, and distress seem bett... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3191275 Fri, 15 Jan 2010 18:05:21 +0100 3191275 http://www.medworm.com/index.php?rid=3191276&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F42612311573j7550%2F Abstract  Primary cough headache, primary exertional headache, primary sexual headache, and idiopathic stabbing headache are included in “Other Primary Headaches” (Group 4) in the International Classification of Headache Disorders, 2nd edition (ICHD-II). Headaches provoked by cough, exertion, and sex have different age distributions, but they do share some clinical and pathogenic characteristics. The triggering activities frequently involve Valsalva-like maneuvers, which may explain part of the pathogenesis. Primary stabbing headache is common and characterized by ultra-short stabbing headaches. All these headache disorders respond well to indomethacin, and they are commonly comorbid with migraine except for primary cough headache. Of note, some patients with sexual hea... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3191276 Fri, 15 Jan 2010 18:05:19 +0100 3191276 http://www.medworm.com/index.php?rid=3191277&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl644u2543755w227%2F This article provides an update on newly approved as well as emerging IT agents and the advances in technology for their delivery. Content Type Journal ArticleDOI 10.1007/s11916-009-0092-zAuthors Erin F. Lawson, University of California, San Diego Division of Pain Medicine, Department of Anesthesiology 9300 Campus Point Drive, #7651 La Jolla CA 92037 USAMark S. Wallace, University of California, San Diego Division of Pain Medicine, Department of Anesthesiology 9300 Campus Point Drive, #7651 La Jolla CA 92037 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3191277 Fri, 15 Jan 2010 07:06:03 +0100 3191277 http://www.medworm.com/index.php?rid=3169383&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr1347x6212436100%2F Abstract  Addiction to opioid analgesics is an important and yet underinvestigated clinical issue, which has substantial implications in opioid therapy for chronic pain management. Problematic opioid use, including compulsive opioid seeking and addiction, arises in some fraction of opioid-treated chronic pain patients. The connection between chronic pain and opioid addiction is a complex interplay between psychological, epidemiological, and neurobiological factors. Herein, we explore this critical relationship. Content Type Journal ArticleDOI 10.1007/s11916-009-0086-xAuthors Adam J. Carinci, Harvard Medical School Division of Pain Medicine, Department of Anesthesia and Critical Care, Massachusetts General Hospital 15 Parkman Street Boston MA 02114 USAJianren Mao, Harvard... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3169383 Sun, 10 Jan 2010 06:53:19 +0100 3169383 http://www.medworm.com/index.php?rid=3169384&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F131n18l65v057425%2F Abstract   Chronic orofacial pain (COFP) is an umbrella term used to describe painful regional syndromes with a chronic, unremitting pattern. This is a convenience term, similar to chronic daily headaches, but is of clinically questionable significance: syndromes that make up COFP require individually tailored diagnostic approaches and treatment. Herein we describe the three main categories of COFP: musculoskeletal, neurovascular, and neuropathic. For many years, COFP and headache have been looked upon as discrete entities. However, we propose the concept that because COFP and headaches share underlying pathophysiological mechanisms, clinical characteristics, and neurovascular anatomy, they should be classified together. Content Type Journal ArticleDOI 10.1007/s11916-009... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3169384 Sun, 10 Jan 2010 06:53:16 +0100 3169384 http://www.medworm.com/index.php?rid=3106069&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqkmt88x204j16665%2F Abstract  Traumatic brain injury (TBI) is highly prevalent in the United States and a common cause of posttraumatic headache (PTH) and disability. The criteria that define PTH include timelines and features that are not based on clearly established physiologic data and may result in the underrecognition and incorrect treatment of these headaches. A clear understanding of the classification of PTH becomes even more elusive when one takes into account combat-related head injuries, which are also highly prevalent and frequently lead to headaches with features that are different from those suffered by civilians with PTH. The fact that tensiontype headache phenotypes are uncommon in military personnel with PTH suggests that there are features unique to the combat environment, wh... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=3106069 Wed, 16 Dec 2009 07:19:45 +0100 3106069 http://www.medworm.com/index.php?rid=2969043&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe8157w8140w4787q%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0079-9Authors Andrew J. Holman, Department of Internal Medicine/Rheumatology at the University of Washington School of Medicine Washington USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / December, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969043 Wed, 04 Nov 2009 19:26:01 +0100 2969043 http://www.medworm.com/index.php?rid=2969044&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw7780475l6gwx231%2F Content Type Journal ArticleDOI 10.1007/s11916-009-0080-3Authors Katherine A. Henry, New York University Langone Medical Center Department of Neurology New York USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / December, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969044 Wed, 04 Nov 2009 19:25:54 +0100 2969044 http://www.medworm.com/index.php?rid=2969045&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdn554783071x74p9%2F Abstract  Chronic pain from arthritis continues to be one of the biggest causes of disability and loss of function in the United States today. This is still the case despite many new insights into the pathophysiology of pain, effective treatment approaches, and new, safer medications that can be used long-term. There are many different types of arthritic problems. New disease-modifying agents that are available for some of these types of arthritic diseases, such as rheumatoid arthritis, have the potential to have a substantial impact on improvement in the long-term prognosis. Despite this optimistic outlook, pain often is a significant problem and should be treated whenever it becomes a barrier to function. To complicate treatment for this condition, the most widely used gr... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969045 Wed, 04 Nov 2009 19:25:48 +0100 2969045 http://www.medworm.com/index.php?rid=2969046&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvnx045wt15357755%2F This article presents an update on the epidemiology and prognosis of TTH in the elderly. Content Type Journal ArticleDOI 10.1007/s11916-009-0076-zAuthors Sara C. Crystal, NYU School of Medicine Department of Neurology 462 First Avenue, Suite NBV-7W11 New York NY 10016 USABrian M. Grosberg Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / December, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969046 Wed, 04 Nov 2009 19:25:41 +0100 2969046 http://www.medworm.com/index.php?rid=2969047&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcj15406684656427%2F Content Type Journal ArticleCategory Current Reports / Pain & Headache / Invited CommentaryDOI 10.1007/s11916-009-0081-2Authors James Fricton, University of Minnesota School of Dentistry Department of Diagnostic and Surgical Science 515 Delaware Street SE Minneapolis MN 55455 USAAna VellyWei OuyangJohn O. Look Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / December, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969047 Wed, 04 Nov 2009 19:25:34 +0100 2969047 http://www.medworm.com/index.php?rid=2969048&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu353728250h70831%2F Abstract  Joint hypermobility syndrome (JHS) was initially defined as the occurrence of musculoskeletal symptoms in the presence of joint laxity and hypermobility in otherwise healthy individuals. It is now perceived as a commonly overlooked, underdiagnosed, multifaceted, and multisystemic heritable disorder of connective tissue (HDCT), which shares many of the phenotypic features of other HDCTs such as Marfan syndrome and Ehlers-Danlos syndrome. Whereas the additional flexibility can confer benefits in terms of mobility and agility, adverse effects of tissue laxity and fragility can give rise to clinical consequences that resonate far beyond the confines of the musculoskeletal system. There is hardly a clinical specialty to be found that is not touched in one way or anothe... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969048 Wed, 04 Nov 2009 19:25:28 +0100 2969048 http://www.medworm.com/index.php?rid=2969049&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb732584xrw61x773%2F Abstract  With the aging of the baby boomer generation, the number of patients with osteoarthritis (OA) is expected to swell, posing treatment challenges. Viscosupplementation, in which hyaluronic acid (HA) is injected into the knee joint, has evolved into an important part of our current therapeutic regimen in addressing the patient with knee pain due to OA. Although suffering from lack of an “evidence-based” approach, and largely funded by industry, there is a growing body of outcome data demonstrating the efficacy of HA in decreasing pain and improving function in patients with knee OA, although no evidence indicates that HA is in any way chondroprotective. The clinical success of HA has led to the ongoing introduction of various forms of HA, although little data are... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969049 Wed, 04 Nov 2009 19:25:21 +0100 2969049 http://www.medworm.com/index.php?rid=2969050&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft524t1002l4171l0%2F Abstract  Tension-type headache (TTH) is the most prevalent primary headache disorder. An important factor in the long-term prognosis of TTH is the overuse of acute medications used to treat headache. There are many reasons why patients with TTH overuse acute medications, including biobehavioral influences, dependency, and a lack of patient education. Chronic daily headache occurs in 4.1% of the general population, and chronic tension-type headache and medication overuse headache (MOH) occur in approximately 2.2% and 1.5%, respectively. A proper diagnosis is essential for the treatment of these patients. Treatment should include pathological considerations concerning TTH and MOH, which include peripheral and central mechanisms. Because TTH with MOH carries the worst prognos... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969050 Wed, 04 Nov 2009 19:25:14 +0100 2969050 http://www.medworm.com/index.php?rid=2969051&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa8526h558940652l%2F Abstract  Enhanced pain perception is common among patients with rheumatoid arthritis (RA). Given the putative role of proinflammatory cytokines in the development of hyperalgesia, a greater understanding of factors that facilitate increased cytokine expression in RA stands to increase understanding of the sources of enhanced pain perception. Patients with RA have significantly greater stress-induced proinflammatory cytokine release. Although absolute deficiencies in cortisol have not been demonstrated, functional abnormalities have been described, including “abnormally normal” cortisol levels in the face of increased inflammation and deficient responses to stressful challenges. Parasympathetic insufficiency has also been demonstrated, which may enhance pain perception ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969051 Wed, 04 Nov 2009 19:25:08 +0100 2969051 http://www.medworm.com/index.php?rid=2969052&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr67540p5l71572p2%2F Abstract  Tension-type headache (TTH) is the most common and most socioeconomically costly headache. Yet our knowledge regarding TTH pathophysiological mechanisms is still in its early stages. Psychological stress and weak coping mechanisms may initiate and propagate physiological pain via activation of second messengers in downstream substrates involved in pain. It seems that peripheral mechanisms are predominant in the episodic type (ETTH), whereas central mechanisms are involved in the chronic type (CTTH) of tension headache. The conversion from ETTH to CTTH is most relevant to the clinician and the patient, as CTTH is the most debilitating. This paper focuses and summarizes our current understanding of central sensitization, the process by which this conversion occurs i... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969052 Wed, 04 Nov 2009 19:24:58 +0100 2969052 http://www.medworm.com/index.php?rid=2969053&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F90352215w3k34480%2F This article reviews the extant literature on sleep disturbance and hyperalgesia in patients with OA. We propose a conceptual working model describing pathways by which sleep disturbance interacts directly with central pain processing mechanisms and inflammatory processes, and indirectly with mood and physical functioning to augment clinical OA pain. The clinical and research implications of the model are discussed. Content Type Journal ArticleDOI 10.1007/s11916-009-0073-2Authors Michael T. Smith, Johns Hopkins Bayview Medical Center 5510 Nathan Shock Drive, Suite 100 Baltimore MD 21224 USAPhillip J. QuartanaRenata M. OkonkwoAdeel Nasir Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13,... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969053 Wed, 04 Nov 2009 19:24:49 +0100 2969053 http://www.medworm.com/index.php?rid=2969054&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq2q52566060h8112%2F This article reviews CTTH, as well as the current pathophysiology and treatment, and discusses controversial issues in the diagnosis of CTTH and CM. Content Type Journal ArticleDOI 10.1007/s11916-009-0077-yAuthors Jessica Ailani, Georgetown University Hospital Department of Neurology 3800 Reservoir Road NW, 7-PHC Washington, DC 20007 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 6 / December, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2969054 Wed, 04 Nov 2009 19:24:43 +0100 2969054 http://www.medworm.com/index.php?rid=2811084&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv3817ll671718576%2F Abstract  Recent studies have clarified the nature of myofascial trigger points (MTrPs). In an MTrP region, multiple hyperirritable loci can be found. The sensory components of the MTrP locus are sensitized nociceptors that are responsible for pain, referred pain, and local twitch responses. The motor components are dysfunctional endplates that are responsible for taut band formation as a result of excessive acetylcholine (ACh) leakage. The concentrations of pain- and inflammation-related substances are increased in the MTrP region. It has been hypothesized that excessive ACh release, sarcomere shortening, and release of sensitizing substances are three essential features that relate to one another in a positive feedback cycle. This MTrP circuit is the connection among spin... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811084 Fri, 18 Sep 2009 06:23:48 +0100 2811084 http://www.medworm.com/index.php?rid=2811086&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F43224438ru180661%2F This article reviews several common aspects of the pathophysiology regarding pain control mechanisms and neuroendocrine dysfunction occurring in FM and migraine, particularly in the chronic form of the latter. We also discuss the participation of hypothalamic and brainstem centers of pain control, the putative role played by neurotransmitters or neuromodulators on central sensitization, and changes in their levels in the cerebrospinal fluid. Understanding their mechanisms will help to establish new treatment strategies for treating these disabling brain disorders. Content Type Journal ArticleDOI 10.1007/s11916-009-0058-1Authors Marcelo Moraes ValençaFabíola Lys MedeirosHugo A. MartinsRodrigo Meirelles MassaudMario F. P. Peres, Instituto Israelita deEnsino e Pesquisa Hospital Al... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811086 Fri, 18 Sep 2009 06:23:47 +0100 2811086 http://www.medworm.com/index.php?rid=2811085&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc551070103140074%2F This article reviews several objective abnormalities or measures that have been identified or used in fibromyalgia, and indicates which of these may be most promising to eventually use as biomarkers to follow the response to treatment or progress of disease over time. Content Type Journal ArticleDOI 10.1007/s11916-009-0056-3Authors Jacob N. AblinDan BuskilaDaniel J. Clauw, University of Michigan Chronic Pain and Fatigue Research Center 24 Frank Lloyd Wright Drive PO Box 385 Ann Arbor MI 48106 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 5 / October, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811085 Fri, 18 Sep 2009 06:23:47 +0100 2811085 http://www.medworm.com/index.php?rid=2811087&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk034p51q77h258j2%2F Abstract  The brain plays a prominent role in the generation and modulation of pain. It contains powerful endogenous pain modulatory systems that can be engaged in a beneficial way by therapeutical intervention. In contrast, pain chronification is associated with maladaptive structural and functional changes that may shift the balance of the modulatory systems. Although pain from myofascial trigger points (MTrPs) is highly prevalent, little is known about its brain manifestations and modulation. Recent neuroimaging data suggest that hyperalgesia from MTrPs is processed in similar regions as hyperalgesia from other pain conditions. However, abnormal hippocampal hypoactivity suggests that dysfunctional stress responses may play an important role in the generation and maintena... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811087 Fri, 18 Sep 2009 06:23:46 +0100 2811087 http://www.medworm.com/index.php?rid=2811088&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F34370u1051718636%2F Abstract  The association of traumatic exposures with posttraumatic stress disorder (PTSD) and other mental health conditions is well known. Patients with chronic pain, particularly headache disorders and fibromyalgia (FM), associated with psychological traumas need a special management strategy. Diagnosis of headache disorders and FM in traumatized patients and collecting the clinical history of a traumatic event or diagnosing PTSD in chronic pain patients is of great importance. Psychotherapy and pharmacotherapeutic options should be started on patients with comorbid PTSD and headache disorders and/or FM. Content Type Journal ArticleDOI 10.1007/s11916-009-0057-2Authors Julio F. P. PeresAndre Leite GonçalvesMario F. P. Peres, Instituto Israelita deEnsino e Pesquisa Hos... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811088 Fri, 18 Sep 2009 06:23:44 +0100 2811088 http://www.medworm.com/index.php?rid=2811091&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F177327168u064711%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0068-zAuthors Vincent T. Martin, University of Cincinnati College of Medicine Division of General Internal Medicine Cincinnati USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 5 / October, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811091 Fri, 18 Sep 2009 06:23:43 +0100 2811091 http://www.medworm.com/index.php?rid=2811090&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F12251176665lw1v2%2F Content Type Journal ArticleCategory Current Reports / Pain & Headache / Invited CommentaryDOI 10.1007/s11916-009-0069-yAuthors Julio Pascual, University Hospital Marqués de Valdecilla Service of Neurology 39008 Santander SpainAgustín Oterino Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 5 / October, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811090 Fri, 18 Sep 2009 06:23:43 +0100 2811090 http://www.medworm.com/index.php?rid=2811089&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr25n3413u2u2g513%2F This article offers an in-depth review of several studies linking psychiatric disorders and stress-related disorders with migraine. We also discuss the role of estrogen in the pathophysiologic overlap between these disorders. Finally, we briefly touch on where future research may be headed, in light of these data. Content Type Journal ArticleDOI 10.1007/s11916-009-0066-1Authors B. Lee Peterlin, Drexel University College of Medicine 245 North 15th Street, MS 423 Philadelphia PA 19102 USAMichael J. KatsnelsonAnne H. Calhoun Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 5 / October, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811089 Fri, 18 Sep 2009 06:23:43 +0100 2811089 http://www.medworm.com/index.php?rid=2811093&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F894583054878710v%2F Abstract  Myofascial pain and fibromyalgia share a number of common features: the patient is uncomfortable; abnormalities can be detected on physical examination; and there is a lack of an objective means to either quantify or visualize their core features. This has undoubtedly contributed to a slowed acceptance of their importance by the medical community. Fortunately, the situation is beginning to change. Although progress may be somewhat slower in fibromyalgia, in which attention appears to focus on pain sensitivity and functional brain imaging, a number of approaches now seem promising in their ability to quantify the physical and biochemical characteristics of the taut bands and trigger points of myofascial pain. This review focuses on myofascial pain with an emphasis ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811093 Fri, 18 Sep 2009 06:23:42 +0100 2811093 http://www.medworm.com/index.php?rid=2811092&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg5766470r8p70827%2F Abstract  Menstrual-related migraine (MRM) affects the majority of female migraineurs, with menstrual-associated attacks reported to be more disabling, longer lasting, and less responsive to traditional treatments than nonmenstrual attacks. Emerging evidence suggests that minimizing or eliminating monthly declines in estrogen concentration may be effective in preventing MRM. This article gives a practical overview of current hormonal options, both contraceptive and noncontraceptive. Our intent is to help the reader better understand the differences in currently available formulations and how some of these agents may be utilized as hormonal preventives of MRM. Content Type Journal ArticleDOI 10.1007/s11916-009-0062-5Authors Anne H. Calhoun, Carolina Headache Institute 10... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811092 Fri, 18 Sep 2009 06:23:42 +0100 2811092 http://www.medworm.com/index.php?rid=2811094&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F068t46935307m541%2F This article explores the physiologic changes occurring during pregnancy that can affect pharmacokinetic properties of drugs and their metabolism. Acute and preventive treatment of migraine during pregnancy and lactation is discussed, with an emphasis on safety to the fetus and nursing infant. Safety and recommended use of medication during pregnancy may be different when use is considered during breastfeeding. A goal of treatment is to balance potential risk of treatment to the fetus and nursing infant with significant relief and return to normal function of the mother. Content Type Journal ArticleDOI 10.1007/s11916-009-0064-3Authors Sylvia Lucas, University of Washington Medical Center The Headache Center 1959 NE Pacific Street Box 356097 Seattle WA 98195 USA Journal Curr... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811094 Fri, 18 Sep 2009 06:23:41 +0100 2811094 http://www.medworm.com/index.php?rid=2811095&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp1310nx161m07419%2F Abstract  Some studies suggest that platelet activation and aggregation are associated with migraine, likely secondary to changes occurring during the acute attack. Evidence also suggests that platelet clots can lodge in small cerebral vessels, and that the resultant is chemia and inflammation can induce cortical spreading depression with aura-like symptoms and pulsatile headache. Endothelial dysfunction, a result of numerous vascular, genetic, and environmental risk factors, is more common in women with migraine and leads to altered hemostasis. When associated with other factors, such as oral contraceptive use, there may be an increased tendency for thrombus formation, secondary migraine with aura, transient ischemic attacks, and stroke. Identifying those migraineurs at hi... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811095 Fri, 18 Sep 2009 06:23:39 +0100 2811095 http://www.medworm.com/index.php?rid=2811097&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Few185p8586837415%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0067-0Authors Mario F. P. Peres, Instituto Israelita deEnsino e Pesquisa Hospital Albert Einstein Sao Paulo Brazil Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 5 / October, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811097 Fri, 18 Sep 2009 06:23:38 +0100 2811097 http://www.medworm.com/index.php?rid=2811096&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe138j769875152h4%2F Abstract  Perimenopause marks a time of change in a woman’s hormonal environment, which is apparent from the resultant irregular periods and vasomotor symptoms. These symptoms can start in the early 40s and continue through to the early 50s. Migraine is also affected by hormonal fluctuations, particularly the natural decline in estrogen in the late luteal phase of the menstrual cycle. This effect of estrogen “withdrawal” on migraine appears to become more predominant during perimenopause. Despite the increased prevalence of headache and migraine in women in their 40s, migraine is underdiagnosed in this population. In women attending with symptoms suggestive of perimenopause, it is important to ask about headache symptoms. Once diagnosed, a number of strategies can be ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2811096 Fri, 18 Sep 2009 06:23:38 +0100 2811096 http://www.medworm.com/index.php?rid=2604123&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5m5711310412948p%2F This article discusses the biology, rationale, evolution, and future direction of radiosurgery for the treatment of pain related to bony metastatic disease. Content Type Journal ArticleDOI 10.1007/s11916-009-0044-7Authors Marsha Haley, University of Pittsburgh Cancer Institute Department of Radiation Oncology 5230 Centre Avenue Pittsburgh PA 15213 USAPeter C. Gerszten Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 4 / August, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604123 Tue, 14 Jul 2009 10:57:55 +0100 2604123 http://www.medworm.com/index.php?rid=2604122&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm72486137nmj5835%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0053-6Authors Dermot R. Fitzgibbon, University of Washington School of Medicine Department of Anesthesiology and Pain Medicine Washington USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 4 / August, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604122 Tue, 14 Jul 2009 10:57:55 +0100 2604122 http://www.medworm.com/index.php?rid=2604125&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fch328x78046426jq%2F This article reviews the role that various imaging modalities play in the management of cancer pain and provides an overview of the latest technological advances. Content Type Journal ArticleDOI 10.1007/s11916-009-0042-9Authors Carlos Cuevas, University of Washington Body Imaging Section, Department of Radiology Box 357115 1959 NE Pacific Street Seattle WA 98195 USADean Shibata Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 4 / August, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604125 Tue, 14 Jul 2009 10:57:54 +0100 2604125 http://www.medworm.com/index.php?rid=2604124&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv88q23561l150823%2F Abstract  Among individuals with episodic migraine, the influence of excessive acute medication use on the development of chronic migraine depends upon within-person characteristics (eg, headache frequency), class of drug, and frequency of medication use. Available data suggest that opioids induce migraine chronification (progression), and the effect is dose dependent (critical dose around 8 days of exposure per month) and more pronounced in men. Barbiturates also induce migraine progression, and the effect is dose dependent (critical dose around 5 days of exposure per month) and more pronounced in women. Triptans induce migraine progression only in those with high migraine frequency at baseline (10–14 days per month), but not overall. NSAIDs protect against migraine prog... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604124 Tue, 14 Jul 2009 10:57:54 +0100 2604124 http://www.medworm.com/index.php?rid=2604126&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4601336635557247%2F Abstract  Neuropathic pain is an increasingly common problem facing the cancer patient. Painful neuropathy can come from various sources and significantly impact quality of life. The most commonly observed scenario is paraesthesia and dysesthesia as a result of toxic effects of chemotherapies on the distal peripheral nerves. Neuropathic pain should be addressed ideally with the help of a neuro-oncologist, and it usually can be successfully treated with a variety of agents, including atypical analgesics such as antidepressants, newer drugs with analgesic benefit, and opioids for more refractory cases. Direct and indirect effects of the primary neoplasm need to be considered in the etiology of specific syndromes of mononeuropathies and plexopathies. Content Type Journal Art... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604126 Tue, 14 Jul 2009 10:57:53 +0100 2604126 http://www.medworm.com/index.php?rid=2604127&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F33n5458656124551%2F This article explores the potential comorbidity between migraine and TMD and the role of TMD as a potential factor to induce chronic migraine. We discuss the similarities between both conditions, review evidence to support the idea that both disorders are comorbid, and highlight the limited evidence suggesting that TMD influence migraine progression. Finally, we discuss the importance of cutaneous allodynia mediating the TMD/frequent headache relationship. Content Type Journal ArticleDOI 10.1007/s11916-009-0050-9Authors Debora Bevilaqua Grossi, University of Sao Paulo Department of Biomechanics Medicine and Rehabilitation of the Locomotor Apparatus Avenida Bandeirantes, 3900 CEP 14.049-900 Ribeirao Preto Sao Paulo BrazilRichard B. LiptonMarcelo E. Bigal Journal Current Pain ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604127 Tue, 14 Jul 2009 10:57:52 +0100 2604127 http://www.medworm.com/index.php?rid=2604129&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft812lp3p09558q63%2F Abstract  Patients with cancer are concerned about their ability to interact with friends and family and to perform activities associated with daily living. The combined effects of the disease process, its treatment with surgery, radiation, and chemotherapy, and the medications used to manage symptoms may all impact cognitive function. Minimizing the effect of each treatment modality on cognitive processing requires an understanding of how these treatment modalities may impact cognition. Content Type Journal ArticleDOI 10.1007/s11916-009-0043-8Authors Christopher LoiselleJason Rockhill, University of Washington Medical Center Department of Radiation Oncology Box 356043 1959 NE Pacific Street Seattle WA 98195 USA Journal Current Pain and Headache ReportsOnline ISSN ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604129 Tue, 14 Jul 2009 10:57:51 +0100 2604129 http://www.medworm.com/index.php?rid=2604128&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj51q7h45u1701mk6%2F This article overviews literature on psychiatric comorbidities and migraine chronification, considers mechanisms underlying this relationship, and notes directions for future clinical and empirical work. Content Type Journal ArticleDOI 10.1007/s11916-009-0052-7Authors Todd A. Smitherman, University of Mississippi Department of Psychology 207 Peabody, University University MS 38677 USAJeanetta C. RainsDonald B. Penzien Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 4 / August, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604128 Tue, 14 Jul 2009 10:57:51 +0100 2604128 http://www.medworm.com/index.php?rid=2604130&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr530g003054tmp81%2F Abstract  It is estimated that nearly half of the global adult population suffers from an active headache disorder, most of whom experience attacks on an episodic basis. The transition from episodic to chronic headache is a poorly understood process. Epidemiological findings demonstrating comorbidity and common risk factors suggest that headache progression or prognosis may be related to the presence of other chronic pain disorders. This review highlights findings from population-based studies on headache and other pain disorders and how they relate to each other, with a focus on understanding headache chronification. We also consider the limitations and methodological challenges in understanding how two different chronic pain disorders may be related. Content Type Journa... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604130 Tue, 14 Jul 2009 10:57:50 +0100 2604130 http://www.medworm.com/index.php?rid=2604132&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq3285p8458225j6g%2F Abstract  Percutaneous vertebroplasty is the injection of bone cement, usually polymethylmethacrylate into the vertebral body. This procedure is most often performed in a percutaneous fashion on an outpatient (or short-stay) basis. Among other indications, the procedure is designated for painful vertebral compression fractures due to primary or metastatic spinal tumors. Published literature favors the use of this procedure in cancer pain management. The overall risk of the procedure is low, although serious complications (including spinal cord compression) can occur. Recent advances in technique and materials may reduce the incidence of adverse outcomes. Proper patient selection and meticulous technique are required to achieve best results and to avoid complications. Con... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604132 Tue, 14 Jul 2009 10:57:49 +0100 2604132 http://www.medworm.com/index.php?rid=2604131&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9v740l231q2606t6%2F This article explores some of the potential mechanisms and the available scientific studies that may explain how sinus headache can become chronic and present to the clinician as a refractory headache disorder. Content Type Journal ArticleDOI 10.1007/s11916-009-0051-8Authors Roger K. Cady, Headache Care Center 3805 Kansas Expressway Springfield MO 65807 USACurtis P. Schreiber Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 4 / August, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604131 Tue, 14 Jul 2009 10:57:49 +0100 2604131 http://www.medworm.com/index.php?rid=2604134&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0p21t0u7m8374784%2F Content Type Journal ArticleCategory Current Reports / Pain & Headache / Invited CommentaryDOI 10.1007/s11916-009-0055-4Authors Avi Ashkenazi, 233 South 6th Street, Apartment 705 Philadelphia PA 19106 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 4 / August, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604134 Tue, 14 Jul 2009 10:57:48 +0100 2604134 http://www.medworm.com/index.php?rid=2604133&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0x24p1nk34031165%2F Abstract  Treatment of pain in the setting of sickle cell disease remains unsatisfactory. The approach remains to treat the pain symptomatically with escalating doses of non-opioid and opioid medications while any underlying inciting process is investigated. For the majority of patients with sickle cell disease, pain will always be part of their lives. Advances in the treatment of sickle cell pain will depend on multiple approaches, including both pharmacologic and nonpharmacologic. Content Type Journal ArticleDOI 10.1007/s11916-009-0047-4Authors Robert E. Richard, University of Washington School of Medicine Seattle Cancer Care Alliance, Adult Sickle Cell Clinic, Puget Sound Health Care System, Division of Hematology 1600 South Columbian Way, S-111-Hem Seattle WA 98108 US... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604133 Tue, 14 Jul 2009 10:57:48 +0100 2604133 http://www.medworm.com/index.php?rid=2604135&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff2106t87l1n55286%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0054-5Authors Marcelo E. Bigal, Merck Research Laboratories Whitehouse Station USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 4 / August, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2604135 Tue, 14 Jul 2009 10:57:46 +0100 2604135 http://www.medworm.com/index.php?rid=2408773&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg3583t0u22225257%2F Abstract  Evaluation of epidermal nerve fiber density (ENFD) allows objective, pathologic, and minimally invasive assessment of small myelinated and unmyelinated cutaneous axons. In addition to providing diagnostic confirmation of neuropathies affecting these “small fibers,” this procedure has advanced clinical care by dramatically increasing awareness of the role of small myelinated and unmyelinated axons in disorders of peripheral nerve and in neuropathic pain. This review highlights the technical aspects of skin biopsy for ENFD determination, the role of skin biopsy in the diagnosis of small-fiber neuropathy and ganglionopathy, and the diagnostic approach to the patient with peripheral neuropathic pain. Content Type Journal ArticleDOI 10.1007/s11916-009-0033-xAutho... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408773 Sun, 10 May 2009 05:50:45 +0100 2408773 http://www.medworm.com/index.php?rid=2408772&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq1vl7782x67v3521%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0030-0Authors Tobias Moeller-BertramMark S. Wallace Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 3 / June, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408772 Sun, 10 May 2009 05:50:45 +0100 2408772 http://www.medworm.com/index.php?rid=2408771&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq7g23h55w664gkj5%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0031-zAuthors Avi Ashkenazi Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 3 / June, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408771 Sun, 10 May 2009 05:50:45 +0100 2408771 http://www.medworm.com/index.php?rid=2408774&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0n5l01138th10355%2F Abstract  Initially described more than 40 years ago, basilar-type migraine has posed diagnostic and therapeutic dilemmas for medical practitioners. Defined by the coexistence of migraine headache with neurological symptoms emanating from either the brainstem or simultaneously from both cerebral hemispheres, basilar-type migraine has been categorized as “atypical” or “complicated” and has been considered more akin to hemiplegic migraine than to migraine with typical aura. Despite the absence of any data convicting basilar-type migraine as a vasospastic condition, the use of triptans in such patients has been considered prohibited. This review focuses on the diagnosis, clinical presentation, available genetic information, and treatment considerations in patients with... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408774 Sun, 10 May 2009 05:50:44 +0100 2408774 http://www.medworm.com/index.php?rid=2408777&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn903160311x33751%2F This article reviews empirically supported and efficacious behavioral approaches to the treatment and management of headaches in general, with an emphasis on migraine and MOH from a biopsychosocial perspective. Evidence-based behavioral medicine treatments for migraine and MOH are reviewed, including patient education, cognitive behavioral therapy, and biobehavioral training (biofeedback, relaxation training, and stress management). Information regarding psychological comorbidities and risk factors for progression of migraine and the development of MOH is also reviewed. Strategies are provided for enhancing adherence and motivation, as well as facilitating medical communication. Content Type Journal ArticleDOI 10.1007/s11916-009-0041-xAuthors Frank Andrasik, University of West F... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408777 Sun, 10 May 2009 05:50:42 +0100 2408777 http://www.medworm.com/index.php?rid=2408776&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe076452468481009%2F Abstract  Migraine has been established as a risk factor for ischemic stroke. Further evidence suggests that migraine is also associated with other ischemic vascular events, including myocardial infarction and cardiovascular death. However, these associations appear to be limited to the subgroup of patients with migraine with aura (MA). Moreover, there is increasing evidence that among patients with MA, additional subgroups exist that carry particular increased risk. The association with ischemic stroke is, for example, particularly strong for younger women with MA who smoke and/or use oral contraceptives. Results from recent studies support an even more complex interrelationship characterized by additional modifying effects of other factors on the association between MA an... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408776 Sun, 10 May 2009 05:50:42 +0100 2408776 http://www.medworm.com/index.php?rid=2408775&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx26734r657753859%2F Abstract  Migraine pain has been attributed to an episode of local sterile meningeal inflammation and the subsequent activation of trigeminal primary afferent nociceptive neurons that supply the intracranial meninges and their related large blood vessels. However, the origin of this inflammatory insult and the endogenous factors that contribute to the activation of meningeal nociceptors remain largely speculative. A particular class of inflammatory cells residing within the intracranial milieu, known as meningeal mast cells, was suggested to play a role in migraine pathophysiology more than five decades ago, but until recently the exact nature of their involvement remained largely unexplored. This review examines the evidence linking meningeal mast cells to migraine and high... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408775 Sun, 10 May 2009 05:50:42 +0100 2408775 http://www.medworm.com/index.php?rid=2408778&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm70j543152w51257%2F Abstract  Neuropathic pain remains a serious medical problem because of patient morbidity and the absence of effective therapeutic interventions. Recent evidence suggests that this type of pain may be particularly difficult to manage because underlying mechanisms are influenced by a variety of factors, including type of injury, site of injury, and time after injury. This situation is exacerbated by the fact that different mechanisms may contribute to unique aspects of neuropathic pain, including ongoing pain as well as mechanical and thermal hypersensitivity. The different ion channels present in primary afferent neurons implicated in each of these aspects of neuropathic pain are reviewed. Content Type Journal ArticleDOI 10.1007/s11916-009-0034-9Authors Andrea M. Harrio... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408778 Sun, 10 May 2009 05:50:41 +0100 2408778 http://www.medworm.com/index.php?rid=2408779&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd388n373kh81301v%2F Abstract  Nerve injury increases the spinal cord expression and/or activity of voltage- and ligand-gated ion channels, peptide receptors, and neuroimmune factors, which then drive dorsal horn neuron hyperexcitability. The intensity and duration of this central sensitization is determined by the net activity of local excitatory and inhibitory neurotransmitter systems, together with ongoing/evoked primary afferent activity and descending supraspinal control. Spinal endogenous inhibitory systems serve as opposing compensatory influences and are gaining recognition for their powerful capacity to restrain allodynia and hyperalgesia. These include numerous G protein-coupled receptors (μ- and δ-opioid, α2- adrenergic, purinergic A1, neuropeptide Y1 and Y2, cannabinoid CB1 and CB... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408779 Sun, 10 May 2009 05:50:40 +0100 2408779 http://www.medworm.com/index.php?rid=2408780&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F50hjj3k183p1111k%2F Abstract  Chronic low back pain is highly prevalent in Western societies. Large epidemiological studies show that 20% to 35% of patients with back pain suffer from a neuropathic pain component. Presently, chronic lumbar radicular pain is the most common neuropathic pain syndrome. The pathophysiology of back pain is complex and nociceptive, and neuropathic pain-generating mechanisms are thought to be involved, which established the term mixed pain syndrome. Neuropathic pain may be caused by lesions of nociceptive sprouts within the degenerated disc (local neuropathic), mechanical compression of the nerve root (mechanical neuropathic root pain), or by action of inflammatory mediators (inflammatory neuropathic root pain) originating from the degenerative disc even without any m... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408780 Sun, 10 May 2009 05:50:39 +0100 2408780 http://www.medworm.com/index.php?rid=2408781&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc8662319448m3621%2F Abstract  Patent foramen ovale (PFO) appears to be associated with migraine with aura (MA), probably through cardiac shunting. PFOs may also be comorbid with cryptogenic strokes. Although multiple open-label, retrospective, and case-controlled studies have noted sometimes dramatic reductions of MA after PFO closure, the only prospective sham-controlled study of PFO closure for MA, MIST, was negative for all primary and secondary measures of migraine improvement. MIST did demonstrate an association between MA and severe PFO shunts prospectively. Difficulty with recruitment closed the MIST II and ESCAPE trials; the PREMIUM and PRIMA randomized controlled trials are ongoing at the time of this writing. Content Type Journal ArticleDOI 10.1007/s11916-009-0037-6Authors Stewar... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408781 Sun, 10 May 2009 05:50:38 +0100 2408781 http://www.medworm.com/index.php?rid=2408782&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fuhj018m20850778m%2F Abstract  Although medication costs make up one of the smallest portions of the overall expense of headache care, it is the segment of expense that often impacts the patient most directly. The advent of triptans marked a major advance in migraine therapy, but their high cost has limited their widespread use. Four options can be considered as potential means to reduce the cost of triptans. These include compulsory licensing, exclusive contracting, over-the-counter availability, and the introduction of generic triptans. Each method impacts the consumer, third-party payer, or pharmaceutical company in a different manner. Content Type Journal ArticleDOI 10.1007/s11916-009-0038-5Authors Glen D. Solomon, Wright State University Department of Medicine, Boonshoft School of Medic... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2408782 Sun, 10 May 2009 05:50:37 +0100 2408782 http://www.medworm.com/index.php?rid=2278692&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm84344x39850n823%2F Abstract  Knowing enough information about pain and its management to adequately care for people in pain may seem challenging, especially for primary care providers who provide the bulk of pain management services in the United States. Few, if any, primary care providers received training beyond the names of a few analgesics and the rudiments of pain assessments. Fortunately, many national and international societies provide health care practitioners with pain-related education, resources, and tools. Education may be tied to pain certification or specialization, or provided solely for the benefit of practitioners. Due in large part to the World Wide Web, much information about pain is readily available online. Content Type Journal ArticleDOI 10.1007/s11916-009-0020-2Autho... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278692 Tue, 17 Mar 2009 07:03:15 +0100 2278692 http://www.medworm.com/index.php?rid=2278700&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb774676507276435%2F This article reviews the physiology of breathing, effects of sleep on respiration, effects of opioids on respiration, potential interactions between sleep and opioids on respiration, and current evidence that chronic opioid use is associated with sleep-disordered breathing. Content Type Journal ArticleDOI 10.1007/s11916-009-0021-1Authors James M. Walker, LDS Hospital Intermountain Sleep Disorder Center 325 8th Avenue and C Street Salt Lake City Utah 84143 USARobert J. Farney Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 2 / April, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278700 Tue, 17 Mar 2009 07:03:13 +0100 2278700 http://www.medworm.com/index.php?rid=2278698&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk03700307w7g7235%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0017-xAuthors Tim P. JürgensArne May Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 2 / April, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278698 Tue, 17 Mar 2009 07:03:13 +0100 2278698 http://www.medworm.com/index.php?rid=2278695&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4360t13l2rpj45n3%2F This article presents a comprehensive review of the literature to date exploring the clinical and experimental applications of VR for pain control. The review details specifi c research methodologies and popular virtual environments. Limitations of the research, recommendations for improvement of future studies, and clinical experiences with VR are also discussed. Content Type Journal ArticleDOI 10.1007/s11916-009-0019-8Authors Nicole E. MahrerJeffrey I. Gold, Childrens Hospital Los Angeles Department of Anesthesiology Critical Care Medicine, Comfort, Pain Management, and Palliative Care Program 4650 Sunset Boulevard, MS #12 Los Angeles CA 90027-6062 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journa... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278695 Tue, 17 Mar 2009 07:03:13 +0100 2278695 http://www.medworm.com/index.php?rid=2278702&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft217u23855x125t8%2F Abstract  Most antidepressants and anticonvulsants used in chronic pain syndromes have dose- and concentration-response curves developed for their application to treat psychiatric disorders. Because these are important clinical tools in medication management of psychiatric syndromes, it is reasonable to expect that utilizing concentration-effect relationships and known sources of pharmacokinetic variability for determining doses for analgesia may also improve treatment tolerability and outcomes. Efforts to identify dosing “therapeutic windows” or minimum “thresholds” for analgesic efficacy have provided useful guidance for initiating treatment, reducing toxicity, and assisting with decision making in the face of limited therapeutic response. This article reviews the... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278702 Tue, 17 Mar 2009 07:03:12 +0100 2278702 http://www.medworm.com/index.php?rid=2278704&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjm54761504771221%2F Abstract  Illness uncertainty is present for both acute and chronic illnesses and has been described in the literature as a cognitive stressor, a sense of loss of control, and a perceptual state of doubt that changes over time. Illness uncertainty is associated with poor adjustment, but often needs to be appraised as a threat to have its deleterious effect. In pain populations, illness uncertainty is related to heightened sensitivity to pain and reduced tolerance of painful stimuli. Illness uncertainty also has been related to maladaptive coping, higher psychological distress, and reduced quality of life. The illness uncertainty literature in relation to pain is somewhat limited but clearly suggests the potential negative impact on the perception of and adjustment to pain. ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278704 Tue, 17 Mar 2009 07:03:11 +0100 2278704 http://www.medworm.com/index.php?rid=2278710&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg1l5l2n383h22152%2F This article reviews the data to date on the prevalence and incidence of the disorder, population differences including gender and race, genetics, comorbid conditions, risk factors for development of the disorder, prognosis, and socioeconomic burden. Content Type Journal ArticleDOI 10.1007/s11916-009-0024-yAuthors Susan W. Broner, St. Luke’s-Roosevelt Hospital The Headache Institute 1000 Tenth Avenue, Suite 1C-10 New York NY 10019 USAJoshua M. Cohen Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 2 / April, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278710 Tue, 17 Mar 2009 07:03:09 +0100 2278710 http://www.medworm.com/index.php?rid=2278708&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg30563771lv2vwnq%2F Abstract  Cluster headache (CH) is a primary headache syndrome that is classified with the trigeminal autonomic cephalalgias. CH treatment involves three steps: acute attack management, transitional therapy, and preventive therapy. Greater occipital nerve block has been shown to be an effective alternative bridge therapy to oral steroids in CH. Botulinum toxin type A has recently been studied as a new preventive treatment for patients with chronic CH, with limited success. Content Type Journal ArticleDOI 10.1007/s11916-009-0028-7Authors Jessica Ailani, Jefferson Headache Center Gibbon Building, 111 South 11th Street, Suite 8130 Philadelphia PA 19107 USAWilliam B. Young Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Vo... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278708 Tue, 17 Mar 2009 07:03:09 +0100 2278708 http://www.medworm.com/index.php?rid=2278706&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr2574j2103110611%2F This article explores empirical research that illustrates how religion/spirituality may impact the experience of pain and may help or hinder the coping process. This article also provides practical suggestions for health care professionals to aid in the exploration of spiritual issues that may contribute to the pain experience. Content Type Journal ArticleDOI 10.1007/s11916-009-0022-0Authors Amy B. Wachholtz, UMass Memorial Medical Center Department of Psychiatry 55 Lake Avenue Worcester MA 01655 USAMichelle J. Pearce Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 2 / April, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278706 Tue, 17 Mar 2009 07:03:09 +0100 2278706 http://www.medworm.com/index.php?rid=2278716&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff0822527x3883q08%2F Abstract  Cluster headache (CH) is a neurovascular headache disease characterized by recurrent, strictly unilateral, severe pain attacks. Despite its typical clinical features, including circadian rhythm of the attacks and ipsilateral autonomic dysfunction, the underlying pathophysiology of CH is still unclear. Electrophysiological data point to central disinhibition of the trigeminal nociceptive system as one of the key mechanisms of CH pain. Therefore, altered habituation pattern and changes within trigeminal-facial neuronal circuits due to central sensitization seem to be involved. One biochemical correlate is probably represented in dysfunctions of serotonergic raphe nuclei-hypothalamic pathways. Structural and functional imaging data show an alteration of hypothalamic ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278716 Tue, 17 Mar 2009 07:03:08 +0100 2278716 http://www.medworm.com/index.php?rid=2278714&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyq57n0143131x01t%2F Abstract  Cluster headache (CH) is a highly disabling condition resulting in severe, recurrent unilateral bouts of pain and accompanying autonomic symptoms. This review describes some current views regarding the underlying pathophysiology covering the pain and cranial autonomic (parasympathetic) activation, and highlights the potential importance of the hypothalamus in CH. The hypothalamus is known to modulate many functions and has been shown to be involved in the pathophysiology of a variety of primary headaches, including CH. Hypothalamic structures are likely to underlie the circadian and circannual periodicity of attacks and contribute to the pain and autonomic disturbances. We discuss the hypothalamic involvement in CH and modulation of trigeminovascular processing an... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278714 Tue, 17 Mar 2009 07:03:08 +0100 2278714 http://www.medworm.com/index.php?rid=2278713&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F810610580684p048%2F Abstract  Patients with cluster headache (CH) have a higher prevalence of sleep apnea, and a possible relationship between these two conditions has been proposed. Although patients suffering from CH attacks often wake up from sleep, sleep apnea has been suggested to be a trigger or an associated abnormality in CH. It has been proposed that regulation of the hypothalamus may be responsible for sleep apnea, and that similiarly CH is generated in the hypothalamus. However, there is evidence that CH and obstructive sleep apnea are not causal, but rather parallel processes both generated in the hypothalamus. The exact role that sleep apnea plays in the perpetuation or precipitation of CH is still to be determined. This paper discusses the proposed pathophysiological mechanisms o... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278713 Tue, 17 Mar 2009 07:03:08 +0100 2278713 http://www.medworm.com/index.php?rid=2278718&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx16j53319uw3415u%2F This article reviews the evidence base for the medical treatments used in CH. Content Type Journal ArticleDOI 10.1007/s11916-009-0029-6Authors Alok TyagiManjit Matharu, Institute of Neurology Headache Group Queen Square WC1N 3BG London England Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 2 / April, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2278718 Tue, 17 Mar 2009 07:03:07 +0100 2278718 http://www.medworm.com/index.php?rid=2129246&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu7316511t358007x%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0001-5Authors Stephen D. ColemanSean Mackey Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 1 / February, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129246 Thu, 22 Jan 2009 09:51:00 +0100 2129246 http://www.medworm.com/index.php?rid=2129251&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9t872h4722415122%2F Abstract  Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) are two noninvasive brain stimulation techniques that can modulate activity in specific regions of the cortex. At this point, their use in brain stimulation is primarily investigational; however, there is clear evidence that these tools can reduce pain and modify neurophysiologic correlates of the pain experience. TMS has also been used to predict response to surgically implanted stimulation for the treatment of chronic pain. Furthermore, TMS and tDCS can be applied with other techniques, such as event-related potentials and pharmacologic manipulation, to illuminate the underlying physiologic mechanisms of normal and pathological pain. This review presents a description and ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129251 Thu, 22 Jan 2009 09:50:57 +0100 2129251 http://www.medworm.com/index.php?rid=2129250&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F982rh614367l8367%2F This article examines the selection of patients, application of the therapy, outcomes, and future uses of stimulation for patients afflicted with these diseases. This article also examines possible study protocols to further examine the overall outcome of these therapies. Content Type Journal ArticleDOI 10.1007/s11916-009-0005-1Authors Timothy R. Deer, The Center for Pain Relief 400 Court Street, Suite 100 Charleston WV 25301 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 1 / February, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129250 Thu, 22 Jan 2009 09:50:57 +0100 2129250 http://www.medworm.com/index.php?rid=2129249&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr31g610740143317%2F This article reviews the unique pharmacologic properties of methadone, including its long-acting nature, highly variable clearance rate, and its antagonism of the N-methyl-d-aspartate receptor. We discuss potential benefits and risks of methadone over other opioid medications. Preclinical studies suggest methadone may reduce abuse potential, tolerance development, and sensitization of nociceptive pathways. Pharmacologic properties of methadone suggest potential greater risk of dangerous or fatal side effects from overdose, QT interval prolongation, and drug interactions. However, clinical studies have yet to confirm that methadone produces either better clinical outcomes or higher rates of adverse events than other opioid analgesics. Clinicians who understand the special properties o... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129249 Thu, 22 Jan 2009 09:50:57 +0100 2129249 http://www.medworm.com/index.php?rid=2129248&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr76t15610586v233%2F This article explores our current understanding of the factors linked to pain duration and the transition from acute to chronic pain in both human and animal models, and across a spectrum of human chronic pain conditions. Content Type Journal ArticleDOI 10.1007/s11916-009-0003-3Authors Charlie K. WangJennifer Myunghae HahIan Carroll, Stanford University School of Medicine 780 Welch Road, Suite 208F Stanford CA 94304-1573 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 1 / February, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129248 Thu, 22 Jan 2009 09:50:57 +0100 2129248 http://www.medworm.com/index.php?rid=2129247&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Faj8l777871h38147%2F Content Type Journal ArticleCategory Clinical Trials ReportDOI 10.1007/s11916-009-0002-4Authors Julio Pascual Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 1 / February, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129247 Thu, 22 Jan 2009 09:50:57 +0100 2129247 http://www.medworm.com/index.php?rid=2129253&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F86l044m05878x168%2F Abstract  Lumbar epidural steroid injections are commonly performed in the United States for treating radicular low back pain. However, the best available data suggest that the benefit afforded by these injections is quite limited; in fact, new data suggest that in geographic areas where many such injections are performed, more and not fewer spine surgeries are actually completed annually. We suggest that further high-quality studies are required and their results respected through their implementation in daily practice to better ensure that only appropriate patients are advised to undergo this procedure. Content Type Journal ArticleDOI 10.1007/s11916-009-0008-yAuthors Charles E. Argoff, Albany Medical Center Albany Medical College 47 New Scotland Avenue MC70 Albany NY 1... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129253 Thu, 22 Jan 2009 09:50:55 +0100 2129253 http://www.medworm.com/index.php?rid=2129252&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg536405551661236%2F Abstract  Epidural steroid injection has been used to treat low back pain for many decades. Numerous randomized trials have examined the efficacy of this approach. This review details the findings of older systematic reviews, newer randomized controlled trials, and two recent systematic reviews that examine the effectiveness of this treatment. Collectively, studies in acute radicular pain due to herniated nucleus pulposus have failed to show that epidural steroid injection reduces long-term pain or obviates the need for surgery. Similarly, there is scant evidence that epidural steroids have any beneficial effect in those with acute low back pain without leg pain or in those with chronic low back or leg pain. However, most studies have demonstrated more rapid resolution of l... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129252 Thu, 22 Jan 2009 09:50:55 +0100 2129252 http://www.medworm.com/index.php?rid=2129254&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy6324l961181nj8n%2F This article discusses some basic topics in the measurement of pain outcomes and addresses issues such as statistical versus clinical significance, daily home data collection, appropriate length of outcome measurement packets, and the possibility of objective pain measurements. This article also reviews some of the more commonly used tools for measuring pain and pain-related disability. By selecting the proper tools and employing them correctly, we can obtain highly reliable and valid measures of pain outcomes in research and clinical care. Content Type Journal ArticleDOI 10.1007/s11916-009-0009-xAuthors Jarred Younger, Stanford University School of Medicine Department of Anesthesia, Division of Pain Management 780 Welch Road, Suite 208C Palo Alto CA 94304-1573 USARebecca McCueSe... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129254 Thu, 22 Jan 2009 09:50:54 +0100 2129254 http://www.medworm.com/index.php?rid=2129258&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdkn0l380r62ht171%2F Abstract  Chronic daily headache (CDH) affects approximately 4% of the population and exerts a significant degree of disability on its sufferers. Chronic migraine (CM) is a subset of CDH that represents migraine without aura occurring on 15 or more days per month for at least 3 months. Although numerous risk factors are associated with the development of CM, the pathophysiology governing its genesis is largely unknown. The role of neurotransmitters, such as glutamate, as well as disruptions of antinociceptive systems and structures, are implicated in CM and are supported by the fact that treatments targeting these abnormalities are effective. Content Type Journal ArticleDOI 10.1007/s11916-009-0013-1Authors Bert B. Vargas, Center for Neurosciences 2450 East River Road Tu... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129258 Thu, 22 Jan 2009 09:50:51 +0100 2129258 http://www.medworm.com/index.php?rid=2129257&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw68062p0h3323244%2F Abstract  Methodology varies greatly in whiplash studies; therefore, results are not directly comparable. Headache seems to be present in 50% to more than 75% of cases in the acute stage, and in 20% to 30% of cases in the early chronic stage. Headache naturally occurs frequently (> 75% of the cases [eg, medico-legal cases]) in patients who consult headache specialists due to protracted symptoms. Malingering may explain some cases, and continuation/activation of prewhiplash headache may explain other cases. De novo headache also seems to occur. This headache may partly have cervicogenic headache characteristics: side-locked unilaterality and occipital onset. In one study, this type of headache was present in 8% at 6 weeks and 1% at 6 years. It was more rare than postwhipl... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129257 Thu, 22 Jan 2009 09:50:51 +0100 2129257 http://www.medworm.com/index.php?rid=2129256&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw14q315716271205%2F Abstract  Chronic daily headache (CDH) is a fairly common but disabling disorder that disproportionately affects women and afflicts individuals across all stages of adulthood. It is a dynamic disorder, marked by relatively high rates of remission and incidence. To some extent, this may be due to the accepted, but not empirically supported, cut-point of 15 headache days per month. The purpose of this article is to understand the CDH classification; determine the prevalence and associated demographic profile of CDH as derived from population-based studies; outline identified risk factors for development or persistence of CDH; and understand which risk factors may be more amenable to intervention. Understanding the factors that put people at risk for developing CDH helps to in... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129256 Thu, 22 Jan 2009 09:50:51 +0100 2129256 http://www.medworm.com/index.php?rid=2129255&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fep77m0h363x416p4%2F Abstract  New daily persistent headache (NDPH) is frequently seen in young patients with chronic daily headache. NDPH begins with a sudden onset, often associated with an infection or other physical stress. This headache syndrome is difficult to treat and may persist for years. This review discusses the epidemiology, comorbid symptoms, evaluation, and treatment of this disorder. Content Type Journal ArticleDOI 10.1007/s11916-009-0010-4Authors Kenneth J. Mack, Mayo Clinic Department of Neurology 200 First Street SW Rochester MN 55905 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 13 Journal Issue Volume 13, Number 1 / February, 2009 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129255 Thu, 22 Jan 2009 09:50:51 +0100 2129255 http://www.medworm.com/index.php?rid=2129260&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv187q1888436wh88%2F Abstract  Menstrual migraine (MM) is either pure, if attacks are limited solely during the perimenstrual window (PMW), or menstrually related (MRM), if two of three PMWs are associated with attacks with additional migraine events outside the PMW. Acute migraine specific therapy is equally effective in MM and non-MM. Although the International Classification of Headache Disorders-Iiclassifies MM without aura, data suggest this needs revision. The studies on extended-cycle oral contraceptives suggest benefits for headache-prone individuals. Triptan mini-prophylaxis outcomes are positive, but a conclusion of “minimal net benefit compared to placebo” is not entirely unwarranted. In a 2008 evidence-based review, grade B recommendations exist for sumatriptan (50 and 100 mg), ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129260 Thu, 22 Jan 2009 09:50:50 +0100 2129260 http://www.medworm.com/index.php?rid=2129259&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F50027822583um66l%2F This article reviews the treatment goals and efficacy of comprehensive pain rehabilitation programs for the treatment of chronic headache. Substantial data demonstrate improved outcomes from rehabilitative treatment for chronic noncancer pain. We present a discussion of the most relevant recent publications on pain rehabilitation in chronic headache disorders. This article describes pain rehabilitation, reviews outcome data for chronic pain patients treated in this setting, and describes the unique applicability of this treatment approach for patients with chronic headache. Particular attention is directed to the rationale for and the results of the withdrawal, in a pain rehabilitation setting, of opioids and simple analgesics, ergots, and triptans that contribute to medication overu... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129259 Thu, 22 Jan 2009 09:50:50 +0100 2129259 http://www.medworm.com/index.php?rid=2129261&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc137141226317273%2F Abstract  At least half of women migraineurs experience menstrual migraine (MM), suggesting a hormonal explanation for the incidence of these headaches. Basic science efforts suggest a relationship between estrogen and the neurotransmitters and neuronal structures critical in the pathophysiology of migraine. The notion that MM is more severe, longer in duration, and more resistant to treatment than headaches occurring at other times during the menstrual cycle may apply more to women seeking treatment for their headaches than to migraineurs in the general population. Triptans have been shown to be effective as both an abortive and short-term preventive treatment, and estradiol has been shown to be an effective short-term preventive treatment. Ergotamines, combinations of dru... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=2129261 Thu, 22 Jan 2009 09:50:48 +0100 2129261 http://www.medworm.com/index.php?rid=1991503&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F03m158425271266p%2F Abstract  NSAIDs still remain the initial therapeutic modality for psoriatic arthritis and inflammatory spondylitis. Disease-modifying antirheumatic drugs have only been proven to be useful in peripheral arthritis, without efficacy in axial inflammatory spondylitis. In recent years, the introduction of tumor necrosis alpha inhibitors into clinical practice has produced a substantial impact in both peripheral and axial disease, with improvement in pain, function, and quality of life. Factors such as cost-effectiveness and safety will need to be better characterized over time. Content Type Journal ArticleDOI 10.1007/s11916-008-0070-xAuthors Hernan Castro-RuedaArthur Kavanaugh, University of California Center for Innovative Therapy, Division of Rheumatology, Allergy and Imm... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991503 Tue, 25 Nov 2008 06:58:11 +0100 1991503 http://www.medworm.com/index.php?rid=1991502&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgt34j362542u0p31%2F This article addresses the epidemiology, inflammatory pathophysiology, pain management techniques (including recent advances), and treatment of the underlying disease itself. Content Type Journal ArticleDOI 10.1007/s11916-008-0071-9Authors Brian S. KirbyJoan C. McTigueN. Lawrence Edwards, 1600 SW Archer Road Gainesville FL 32610 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 6 / December, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991502 Tue, 25 Nov 2008 06:58:11 +0100 1991502 http://www.medworm.com/index.php?rid=1991501&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1641815732n402h3%2F Abstract  Tension-type headache (TTH) is the most prevalent form of primary headache in the general population. We discuss advances in the treatment of TTH. We briefly review nonpharmacologic therapies and then focus on current pharmacologic strategies. For acute treatment, the most common interventions involve the use of simple analgesics and anti-inflammatory medications, often taken by the patient without a prescription. For preventive treatment, amitriptyline is the best-studied drug, but nortriptyline, mirtazapine, tizanidine, the selective serotonin reuptake inhibitors, and other medications can be used. We close by discussing potential future therapies, including calcitonin gene-related peptide receptor antagonism, as well as substance P and the nitric oxide pathways... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991501 Tue, 25 Nov 2008 06:58:11 +0100 1991501 http://www.medworm.com/index.php?rid=1991500&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1k6n826l144v2952%2F Abstract  The question of whether tension-type headache (TTH) and migraine represent two points on a continuum has been debated for decades. Skeptics of the continuum model support their view by noting that the characteristics of these two headaches and the demographics of the individuals who suffer from them are undeniably distinct. In the clinical setting, however, these disorders exhibit more similarities than differences. TTH and migraine may exhibit similar associated features (even within the constraints of diagnostic criteria), respond effectively to similar medications, share similar demographics among certain age groups, and may each have genetic influences. These findings suggest that TTH and migraine may be more intimately related than would be suggested by their... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991500 Tue, 25 Nov 2008 06:58:11 +0100 1991500 http://www.medworm.com/index.php?rid=1991507&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6q28w6971v4r413v%2F Content Type Journal ArticleDOI 10.1007/s11916-008-0066-6 Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 6 / December, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991507 Tue, 25 Nov 2008 06:58:10 +0100 1991507 http://www.medworm.com/index.php?rid=1991506&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn08445xtgx272011%2F Abstract  A flurry of recent randomized, placebo-controlled trials assessing dissimilar pharmacotherapeutic treatment options for fibromyalgia (FM) have been presented in the past few years. This review evaluates these trials in light of recent pathophysiological concepts germane to FM, including mood disorders, autonomic dysregulation, altered sleep stage architecture, and the diagnostic tender point controversy. Studies with gabapentin, pregabalin, duloxetine, milnacipran, sodium oxybate, and pramipexole for treatment of FM are discussed. Content Type Journal ArticleDOI 10.1007/s11916-008-0067-5Authors Andrew J. Holman, Pacific Rheumatology Research 4300 Talbot Road South, Suite 101 Renton WA 98055 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-30... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991506 Tue, 25 Nov 2008 06:58:10 +0100 1991506 http://www.medworm.com/index.php?rid=1991505&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff550k47211t4nh77%2F This article reviews positive results of recent monotherapy trials of several norepinephrine and serotonin reuptake inhibitors. Although there has been little assessment of combination therapy in FM, this review outlines the basis for rational treatment using this approach (in order to most effectively treat multiple symptom domains). Controlled monotherapy trials of medications currently being approved for FM demonstrate significant effect on pain, patient global impression of change, and function. Trials are currently being developed to assess the potential additive or synergistic effects of combined central pharmacotherapy and to assess the safety and tolerability of this approach. Content Type Journal ArticleDOI 10.1007/s11916-008-0068-4Authors Philip J. Mease, Swedish Medic... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991505 Tue, 25 Nov 2008 06:58:10 +0100 1991505 http://www.medworm.com/index.php?rid=1991504&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpv7t4763301gn063%2F Abstract  Back pain is one of the most common patient complaints brought forth to physicians. Mechanical back pain accounts for 97% of cases, arising from spinal structures such as bone, ligaments, discs, joints, nerves, and meninges. Acute back pain in the absence of progressive neurologic deficits and other underlying nonmechanical causes may be treated conservatively, with specific emphasis on maintaining activity levels and function. Mechanical back pain persisting for more than 4 to 6 weeks may warrant further diagnostic testing and imaging. Common causes of mechanical back pain include spinal stenosis, herniated discs, zygapophysial joint pain, discogenic pain, vertebral fractures, sacroiliac joint pain, and myofascial pain. A wide variety of treatments are available,... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991504 Tue, 25 Nov 2008 06:58:10 +0100 1991504 http://www.medworm.com/index.php?rid=1991510&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl152rp01044t167h%2F Abstract  Although pharmacotherapy with NSAIDs and tricyclic antidepressants comprises the traditional treatment of tension-type headaches (TTHs), the use of other therapeutic approaches in combination with medications can increase the success of treatment. Patients with comorbid mood disorders and unremitting headaches may particularly benefit from some non-pharmacologic approaches. This review focuses on complementary and alternative approaches to TTH treatment, including psychological therapies, acupuncture, and physical treatments. Content Type Journal ArticleDOI 10.1007/s11916-008-0076-4Authors Christina Sun-Edelstein, The New York Headache Center 30 East 76th Street New York NY 10021 USAAlexander Mauskop Journal Current Pain and Headache ReportsOnline ISSN 1... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991510 Tue, 25 Nov 2008 06:58:09 +0100 1991510 http://www.medworm.com/index.php?rid=1991509&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv746837682j38652%2F Abstract  The diagnosis of tension-type headache (TTH) is divided into two categories: episodic TTH and chronic TTH. It is important to differentiate TTH from other headaches, including primary and secondary headaches. Significant overlap in the diagnostic criteria makes it difficult to differentiate TTH from other headache disorders and, in particular, migraine. A controversy exists about whether TTH and migraine represent a continuum of the same pathophysiological process. Content Type Journal ArticleDOI 10.1007/s11916-008-0074-6Authors Sara Sacco, Carolinas Headache Clinic 1450 Matthews Township Parkway, Suite 340 Matthews NC 28105 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issu... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991509 Tue, 25 Nov 2008 06:58:09 +0100 1991509 http://www.medworm.com/index.php?rid=1991508&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd00510x72r886012%2F Abstract  Tension-type headache (TTH) is a common disease that is usually minimally impairing. However, more chronic TTH can be associated with significant disability and psychological comorbidity. Psychological assessment can help elucidate the biopsychosocial issues that complicate TTH and reveal the patient’s coping styles. Psychological therapies, such as relaxation training, cognitive behavioral therapy, and biofeedback, may be helpful in reducing the frequency of TTHs and decrease the associated disability. Special populations, including pediatric patients, pregnant patients, and geriatric patients, may especially benefit from psychological interventions. Further work needs to be done in researching the effects of psychological treatments and making them available t... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991508 Tue, 25 Nov 2008 06:58:09 +0100 1991508 http://www.medworm.com/index.php?rid=1991513&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb1g7v683mq817146%2F Abstract  The risk of migraine is increased among women during a 5-day perimenstrual window that starts 2 days before the onset of menses and continues through the first 3 days of menstruation. For some women with menstrual migraine, headaches that occur at this time are more severe, of longer duration, and more disabling. Although it is recognized that menstrual migraine requires specific management, there remain a number of unmet needs. In particular, comorbidity can result in women with menstrual migraine presenting to obstetrician/gynecologists or psychiatrists rather than primary care physicians or neurologists. Failure to diagnose menstrual migraine will lead to suboptimal management. Accurate diagnosis is insufficient unless it results in effective treatment strategie... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991513 Tue, 25 Nov 2008 06:58:08 +0100 1991513 http://www.medworm.com/index.php?rid=1991512&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk8v6h05043572777%2F Abstract  Differences between menstrually related migraine (MRM) and non-MRM are subtle. Preconception that population-based trials do not show differences, but that clinic-based trials showed severe, longer, and clinically refractory menstrual migraines, turns out to be simplistic. This review examines studies comparing and contrasting MRM and non-MRM. All of the pertinent studies show increase of migraine around menses. A judicious reading of the studies suggests that MRM is probably more severe in pain intensity than non-MRM. MRM is more disabling than non-MRM. MRM in clinics is more likely to have both worse prodrome and nausea. A significant subset of MRM patients has poorer response to acute medication. Overall, it appears that MRM is more severe than non-MRM when con... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991512 Tue, 25 Nov 2008 06:58:08 +0100 1991512 http://www.medworm.com/index.php?rid=1991511&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu40wt31231586552%2F Abstract  Hormonal and nonhormonal factors play a role in the pathophysiology of menstrual migraine, but estrogen withdrawal appears to be the most potent of these factors. It is postulated that estrogen withdrawal directly enhances excitability of trigeminal afferents, modulates the synthesis of neuropeptides, activates/deactivates specific neurotransmitter systems, and influences the function of microglia. These changes could activate and/or sensitize the trigeminal system and increase the likelihood of migraine headache during perimenstrual time periods. Three new theories are advanced in this article to explain the pathophysiology of menstrual migraine. Only through an understanding of the mechanisms involved in menstrual migraine can we gain insight into the management... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1991511 Tue, 25 Nov 2008 06:58:08 +0100 1991511 http://www.medworm.com/index.php?rid=1888440&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv1653l31r6413264%2F Abstract  Parents frequently ask health care professionals to provide “natural” migraine care for their children and often use herbs, minerals, vitamins, and supplements to treat their children’s migraines, thinking that these over-the-counter alternatives are less toxic than prescription medications. The only randomized controlled trial on any alternative treatment for pediatric migraine is for magnesium, and the results were equivocal. Results of two other uncontrolled trials of magnesium, one for migraine and one for episodic tension-type headache, were positive. There is one positive uncontrolled trial each for coenzyme Q10 and Petasites for prevention of pediatric migraine. There are no trials to indicate the safety or efficacy of riboflavin or feverfew for pedia... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888440 Fri, 17 Oct 2008 09:42:58 +0100 1888440 http://www.medworm.com/index.php?rid=1888442&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu3302463q2117x7j%2F This article presents limitations of the present diagnostic criteria for migraine, and the proposed modifications to these criteria may assist the clinician with early recognition. Further research in pediatric headaches is needed to help reveal additional pathophysiologic mechanisms and improve diagnostic criteria. Content Type Journal ArticleDOI 10.1007/s11916-008-0060-zAuthors Paul Winner, Nova Southeastern University Palm Beach Headache Center, Premiere Research Institute at Palm Beach Neurology 4631 N. Congress Avenue West Palm Beach FL 33407 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 5 / October, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888442 Fri, 17 Oct 2008 09:42:57 +0100 1888442 http://www.medworm.com/index.php?rid=1888441&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcn6427151l205u63%2F Abstract  A history of headaches in a family is very frequently noted when evaluating a child for recurrent, episodic headaches. Oftentimes, these headaches have migraine features, although the family may deny a history of migraine. This positive family history implies an inherited or genetic basis as a component to the underlying pathophysiology of primary headaches. A variety of methodology has begun to elucidate this contribution, including historical observation, population-based studies of families and twins, gene polymorphism association studies, and specific gene identification for isolated migraine subtypes. This line of investigation should progress in the future to a better understanding of migraine and clarification of the diagnostic subtypes for a genotype-phenot... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888441 Fri, 17 Oct 2008 09:42:57 +0100 1888441 http://www.medworm.com/index.php?rid=1888444&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftn20264gk1555u1t%2F This article reviews the current and emerging literature about the pathophysiology and neurobiology of chronic widespread musculoskeletal pain. Widespread musculoskeletal pain results in changes in the central nervous system in human subjects and animal models. These changes likely reflect alterations in supraspinal modulation of nociception, and include increases in excitatory and decreases in inhibitory modulation pathways. These alterations in excitation and inhibition likely drive changes observed in the spinal cord to result in central sensitization, and the consequent pain and hyperalgesia. Content Type Journal ArticleDOI 10.1007/s11916-008-0057-7Authors Josimari M. DeSantanaKathleen A. Sluka, University of Iowa Physical Therapy and Rehabilitation Science, 1-242 MEB Iowa Ci... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888444 Fri, 17 Oct 2008 09:42:56 +0100 1888444 http://www.medworm.com/index.php?rid=1888443&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb646355438663888%2F This article offers suggestions as to the mechanisms via which LTrP-related pathophysiology may explain the clinical examination findings associated with LTrP-containing and functionally related muscles. Content Type Journal ArticleDOI 10.1007/s11916-008-0058-6Authors Karen R. Lucas, RMIT University Clinical Neuroscience Research Group, School of Health Sciences PO Box 71 Bundoora Melbourne Victoria Australia 3083 Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 5 / October, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888443 Fri, 17 Oct 2008 09:42:56 +0100 1888443 http://www.medworm.com/index.php?rid=1888447&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F96j011k845p1611v%2F Abstract  Fibromyalgia syndrome (FMS) is now understood as a chronic pain syndrome, and recent evidence indicates it is not a pure psychosomatic disorder. We review the current knowledge in FMS pain pathways, focusing on the central system sensitization phenomenon and the abnormalities in the inhibitory pain systems. Chronic headache is one of the most common symptoms in FMS, and better knowledge of their common pathophysiologic features can help us understand both conditions better. These features include the nerve growth factor actions and failure of the endocannabinoid system. In addition, we review new immunological aspects of FMS, both in their humoral (autoantibodies, antipolymer antibodies) and cytokine (interleukin-2) aspects. Content Type Journal ArticleDOI 10.10... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888447 Fri, 17 Oct 2008 09:42:55 +0100 1888447 http://www.medworm.com/index.php?rid=1888446&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr227l2645p730440%2F Abstract  The influence of psychosocial factors on pain experience and patient response has received increasing interest and recognition. Patients with chronic pain from several sources (eg, musculoskeletal, cancer, or sickle cell) usually report that religiousness and spirituality are important in their lives. Prayer is the most used complementary therapy; religious coping is among the most common strategies used to deal with pain. Religious variables are not usually associated with pain measures, except in some studies indicating that petitionary prayer is related to higher pain levels, possibly suggesting a turning to religion due to increasing pain. The best available evidence supports a positive association between religiousness and spirituality, with higher well-being... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888446 Fri, 17 Oct 2008 09:42:55 +0100 1888446 http://www.medworm.com/index.php?rid=1888445&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa6l9366655w54827%2F Abstract  Migraine and fibromyalgia are prevalent and disabling disorders with few preventive medications approved by the US Food and Drug Administration (FDA). Neuromodulators (or antiepileptic drugs; AEDs) are often effective in the treatment of these conditions. Divalproex sodium and topiramate are FDA-approved AEDs for migraine. For fi bromyalgia, pregabalin has recently been approved in the United States. We review the use of AEDs in the preventive treatment of these highly prevalent disorders. Content Type Journal ArticleDOI 10.1007/s11916-008-0056-8Authors Abouch V. KrymchantowskiJuline BrysonRichard B. LiptonMarcelo E. Bigal, Merck Research Laboratories 1 Merck Drive Whitehouse Station NJ 08889 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888445 Fri, 17 Oct 2008 09:42:55 +0100 1888445 http://www.medworm.com/index.php?rid=1888450&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy732512138r12qj1%2F Abstract  Headache can be caused by primary entities (as in migraine or tension-type headache) or the pain may result from secondary causes, such as brain tumors, idiopathic intracranial hypertension, chronic meningitis, hydrocephalus, drug intoxications, paranasal sinus disease, or acute febrile illnesses (eg, influenza). To determine the nature of a child’s headache, the evaluation begins with a thorough medical history, followed by methodic physical examination with measurement of vital signs and complete neurologic examination. The diagnosis of primary headache disorders such as migraine and tension-type rests principally on clinical criteria as set forth by the International Headache Society (http://www.i-h-s.org/). Clues to the presence and identification of secondar... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888450 Fri, 17 Oct 2008 09:42:54 +0100 1888450 http://www.medworm.com/index.php?rid=1888449&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F851333xp440088w5%2F This article reviews the physiology of trigger points, with a focus on the latest understanding of their biochemistry. The importance of facial muscle and extraocular muscle trigger points is only beginning to be understood; the data exploring their role in headache are reviewed. The concept of central sensitization and the way in which it relates to trigger points and headache is explained, along with treatment strategies for helping patients with their pain. Content Type Journal ArticleDOI 10.1007/s11916-008-0059-5Authors Cristin A. McMurrayZahid H. Bajwa, Arnold Pain Management Center Beth Israel Deaconess Medical Center One Brookline Place, Suite 105 Brookline MA 02445 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Vol... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888449 Fri, 17 Oct 2008 09:42:54 +0100 1888449 http://www.medworm.com/index.php?rid=1888448&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq070010jn87g737x%2F Content Type Journal ArticleDOI 10.1007/s11916-008-0053-y Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 5 / October, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888448 Fri, 17 Oct 2008 09:42:54 +0100 1888448 http://www.medworm.com/index.php?rid=1888452&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx8824138v4677jxl%2F Abstract  Migraine commonly affects adolescents, and menstrual migraine often begins in young girls. If undiagnosed or ineffectively treated, migraine can lead to disability, school absenteeism, emotional or social difficulties, and chronification of headache. Thus, recognizing and accurately diagnosing migraine and menstrual migraine, developing effective treatment strategies (both pharmacologic and nonpharmacologic), and educating both the adolescent and her parents are important in order to minimize the potential early disability of this disorder and limit the otherwise likely progression of migraine to a disabling disorder of adulthood. Content Type Journal ArticleDOI 10.1007/s11916-008-0065-7Authors Christine L. LaySusan W. Broner, St. Luke’s-Roosevelt Hospital C... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888452 Fri, 17 Oct 2008 09:42:53 +0100 1888452 http://www.medworm.com/index.php?rid=1888451&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff075570068446m27%2F This article discusses these secondary causes of headaches due to primary brain etiologies, focusing on aspects of the history that should lead a neurologist to order neuroimaging or electroencephalographic studies for these children. Content Type Journal ArticleDOI 10.1007/s11916-008-0063-9Authors Rooman Ahad, Johns Hopkins Hospital Department of Neurology, Division of Pediatric Neurology Suite 2158, 200 N. Wolfe Street Baltimore MD 21287 USAEric H. Kossoff Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 5 / October, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1888451 Fri, 17 Oct 2008 09:42:53 +0100 1888451 http://www.medworm.com/index.php?rid=1886633&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd9622024091106n7%2F This article reviews cancer pain syndromes related to cancer and sequelae of treatment. We discuss the assessment and treatment of cancer pain with pharmacotherapy and chemotherapy, and the role of pain specialists. There are numerous barriers to care, which arise from both the physician and patient. We review approaches that diminish these barriers to improve treatment of cancer pain. Content Type Journal ArticleDOI 10.1007/s11916-008-0046-xAuthors Keith D. Eaton, University of Washington Seattle Cancer Care Alliance 825 Eastlake Avenue East Seattle WA 98109 USADeborah A. Frieze Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / August, 2008 (Source: Current Pain and Headach... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886633 Thu, 16 Oct 2008 09:59:40 +0100 1886633 http://www.medworm.com/index.php?rid=1886632&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw25j63764861w475%2F We describe current approaches to assess, define, characterize, and treat breakthrough cancer pain, and summarize recent clinical research on novel agents, novel routes of drug delivery, and other advances in its management. Content Type Journal ArticleDOI 10.1007/s11916-008-0042-1Authors Neil A. Hagen, Alberta Cancer Board Tom Baker Cancer Centre Calgary CanadaPatricia BiondoCarla Stiles Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / August, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886632 Thu, 16 Oct 2008 09:59:40 +0100 1886632 http://www.medworm.com/index.php?rid=1886631&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw4610vh036673055%2F Content Type Journal ArticleDOI 10.1007/s11916-008-0041-2 Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / August, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886631 Thu, 16 Oct 2008 09:59:40 +0100 1886631 http://www.medworm.com/index.php?rid=1886638&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj203k14771453820%2F Abstract  Recent literature shows an interest in the relationship between psychiatric disorders and headache. This relationship is complex and multifaceted, with existing studies confirming high rates of comorbidity between psychiatric disorders (especially depression and anxiety) and migraine and tension-type headache, implicating comorbid psychiatric disorders as risk factors for headache progression and chronification, and underscoring the need for assessment and treatment of relevant disorders. A smaller amount of literature has focused on headache that presents exclusively during and secondary to a psychiatric disturbance; this phenomenon has been termed “headache attributed to psychiatric disorder.” We review recent developments in the relationship between psychiat... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886638 Thu, 16 Oct 2008 09:59:39 +0100 1886638 http://www.medworm.com/index.php?rid=1886637&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb24vk6760x027v36%2F This article highlights recognition and management of psychiatric syndromes in the context of cancer care. Content Type Journal ArticleDOI 10.1007/s11916-008-0045-yAuthors Mitchell R. Levy, University of Washington Department of Psychiatry and Behavioral Sciences Box 356560 Seattle WA 98195 USAJesse R. Fann Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / August, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886637 Thu, 16 Oct 2008 09:59:39 +0100 1886637 http://www.medworm.com/index.php?rid=1886636&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb0158836761p3070%2F Abstract  Burning mouth syndrome (BMS) is a chronic disease characterized by burning of the oral mucosa associated with a sensation of dry mouth and/or taste alterations. BMS occurs more frequently among postmenopausal women. The pathophysiology of the disease is still unknown, and evidence is conflicting; although some studies suggest a central origin, others point to a peripheral neuropathic origin. The efficacy of some medications in the treatment of BMS suggests that the dopaminergic system may be involved. Content Type Journal ArticleDOI 10.1007/s11916-008-0047-9Authors José G. Speciali, Hospital das Clínicas de Ribeirão Preto Departamento de Neurologia Avenida Bandeirantes, 3900 Ribeirão Preto, São Paulo 14400-000 BrazilJuliana Stuginski-Barbosa Journal... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886636 Thu, 16 Oct 2008 09:59:39 +0100 1886636 http://www.medworm.com/index.php?rid=1886635&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F481th8488561423r%2F Abstract  The use of intrathecal analgesics is an important treatment consideration for many patients with chronic cancer pain. This review describes the various opioid and nonopioid analgesics that have been used in this setting, including morphine, hydromorphone, fentanyl, meperidine, methadone, sufentanil, local anesthetics, clonidine, ketamine, baclofen, midazolam, betamethasone, and octreotide. We discuss available evidence for their analgesic and adverse effects. Content Type Journal ArticleDOI 10.1007/s11916-008-0043-0Authors Scott NewsomeBridget K. FrawleyCharles E. Argoff, Albany Medical College Albany USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886635 Thu, 16 Oct 2008 09:59:39 +0100 1886635 http://www.medworm.com/index.php?rid=1886634&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl074x33450236501%2F Abstract  Palliative care is an interdisciplinary approach to relieving aversive symptoms in people with life-threatening illnesses; it aims to improve the lives of patients and their loved ones, the “patient-family unit.” Palliative care should occur in parallel with all other medical interventions. Indeed, good symptom management is important in helping patients cope with the unpleasantness associated with potentially curative or life-prolonging interventions; it is absolutely essential near the end of life. Unrelieved pain is the symptom that people fear the most. In most cases, adequate pain relief can be achieved with systemic medications alone. When systemic medications fail, due to inadequate analgesia or burdensome side effects, invasive techniques may complemen... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886634 Thu, 16 Oct 2008 09:59:39 +0100 1886634 http://www.medworm.com/index.php?rid=1886642&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq556366557wg3485%2F Abstract  Caffeine is the most widely consumed psychostimulant drug in the world. With intermittent exposures, caffeine may act as a mild analgesic for headache or as an adjuvant for the actions of other analgesics. Chronic repetitive exposures to caffeine increase the risks for development of analgesic-overuse headache, chronic daily headache, and physical dependency. Cessation of caffeine use after chronic exposures leads to a withdrawal syndrome with headache as a dominant symptom. At dosages achieved by common dietary intake, caffeine acts as a potent antagonist of central and peripheral nervous system adenosine receptors. The complex effects of caffeine on headache disorders suggest important roles for adenosine in these disorders and in the induction of caffeine depen... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886642 Thu, 16 Oct 2008 09:59:38 +0100 1886642 http://www.medworm.com/index.php?rid=1886641&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F914304259618p7x0%2F Abstract  The term ophthalmoplegic migraine (OM) was first coined by Charcot in 1890. This condition was included as a migraine variant in the first Headache Classification of the International Headache Society in 1988. Based on postcontrast enhancement seen on MRI in some patients who were diagnosed with OM, there was a suggestion that this could be an inflammatory/demyelinating disorder; therefore, it was moved out of the “migraine” group and repositioned as a “neuralgia” in the revised 2004 classification. However, there have been subsequent reports in the literature in which there was no enhancement on postcontrast MRI. Based on a survey of literature on OM in the post-imaging era, this article highlights the fact that enhancement on magnetic resonance is not a ... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886641 Thu, 16 Oct 2008 09:59:38 +0100 1886641 http://www.medworm.com/index.php?rid=1886640&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhv17jt67821700w6%2F Abstract  This review discusses headaches secondary to disorders of homeostasis, formerly known as “headaches associated with metabolic or systemic diseases.” They include the headaches attributed to 1) hypoxia and/or hypercapnia (high altitude, diving, sleep apnea); 2) dialysis; 3) arterial hypertension; 4) hypothyroidism; 5) fasting; and 6) cardiac cephalalgia. For each headache type, we discuss the clinical features and diagnosis, as well as therapeutic strategies. Content Type Journal ArticleDOI 10.1007/s11916-008-0049-7Authors Marcelo E. Bigal, Merck Research Laboratories One Merck Drive PO Box 100 Whitehouse Station NJ 08889 USAJonathan Gladstone Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 1... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886640 Thu, 16 Oct 2008 09:59:38 +0100 1886640 http://www.medworm.com/index.php?rid=1886639&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F244478g335q57131%2F This article reviews common ocular conditions that are associated with head pain, and some secondary causes of headache with neuro-ophthalmic neuro-ophthalmic manifestations. Content Type Journal ArticleDOI 10.1007/s11916-008-0050-1Authors Deborah I. Friedman, University of Rochester School of Medicine and Dentistry Departments of Ophthalmology and Neurology 601 Elmwood Avenue Box 659 Rochester NY 14642 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 4 / August, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1886639 Thu, 16 Oct 2008 09:59:38 +0100 1886639 http://www.medworm.com/index.php?rid=1871090&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw808683420236r53%2F Abstract  Recent advances in the development and administration of chemotherapy for malignant diseases have led to prolonged survival of patients and the promise of a return to normal lives. This progress comes with a price, however, and the nervous system is frequently the target of therapy-induced toxicity. Unlike more immediate toxicities that affect the gastrointestinal tract and bone marrow, chemotherapy-induced neurotoxicity is frequently delayed in onset and may progress over time. In the peripheral nervous system, the major brunt of the toxic attack is directed against the peripheral nerve, targeting the neuronal cell body, the axonal transport system, the myelin sheath, and glial support structures, resulting in chemotherapy-induced peripheral neuropathy. Conten... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1871090 Fri, 10 Oct 2008 08:18:31 +0100 1871090 http://www.medworm.com/index.php?rid=1871089&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnr2rm6101h14hh34%2F Abstract  Fibromyalgia (FM) is a form of nonarticular rheumatism characterized by long-term (> 3 months) and widespread musculoskeletal pain. However, the biophysiology of FM has remained elusive, and the treatment remains mainly empirical. There are numerous hypotheses about the pathophysiology of chronic widespread pain and FM; one includes a possible role of cytokines. Cytokines play a role in diverse clinical processes and phenomena such as fatigue, fever, sleep, pain, stress, and aching. Cytokines related to acute or repetitive tissue injuries may be responsible for long-term activation of spinal cord glia and dorsal horn neurons, thus resulting in central sensitization. Pain, stiffness, and depression in FM could be associated with some signs of inflammatory respon... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1871089 Fri, 10 Oct 2008 08:18:31 +0100 1871089 http://www.medworm.com/index.php?rid=1871095&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbq3254081u378251%2F Abstracts  Diabetes is the most common cause of peripheral neuropathy, and painful diabetic neuropathy (PDN) affects approximately 30% of diabetic patients with neuropathy. It is extremely distressing for the patient and poses significant management difficulties because no treatment provides total relief, and side effects of therapy are a major limiting factor for titrating therapy. Understanding the pathogenesis of diabetic neuropathy may lead to the development of new treatments to prevent nerve damage, and a better understanding of the mechanisms that modulate pain may lead to more effective relief of painful symptoms. We provide an update on the pathogenesis, diagnosis, and treatment of PDN. Content Type Journal ArticleDOI 10.1007/s11916-008-0034-1Authors Mitra Tava... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1871095 Fri, 10 Oct 2008 08:18:30 +0100 1871095 http://www.medworm.com/index.php?rid=1871094&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc2r1358811214809%2F Abstract  Complex regional pain syndrome (CRPS) is still a puzzling disease. Although pathophysiologic understanding has improved, not every aspect of this challenging neuropathic pain syndrome has been explored. Typical symptoms of CRPS are sensory, motor, and autonomic dysfunctions. In most cases, CRPS occurs after a fracture, limb trauma, or lesion of the peripheral or central nervous system. Sometimes, symptoms develop without any trauma. Recent pathophysiologic concepts basically consider three major mechanisms: enhanced peripheral neurogenic inflammation, dysfunction of the sympathetic nervous system, and structural reorganization in the central nervous system. Moreover, a genetic predisposition may explain increased vulnerability. Treatment usually requires a multidi... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1871094 Fri, 10 Oct 2008 08:18:30 +0100 1871094 http://www.medworm.com/index.php?rid=1871093&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4242n9381485682k%2F Abstract  Complex regional pain syndrome type I (CRPS-I) can affect an extremity after minor trauma or operation. The pathogenesis of this syndrome is unclear. It has clinical signs of severe local inflammation as a result of an exaggerated inflammatory response, but neurogenic dysregulation is also a contributor. Several studies investigated the role of inflammatory mediators and cytokines thus far; however, the results are heterogeneous and vary between different settings. This review summarizes recent study results that show a clear underlying inflammatory response at the local site, where systemic responses seem to be inconsistent. An induction of CRPS-like symptoms by application of neuroinflammatory mediators was shown recently. Local inflammation is involved in the p... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1871093 Fri, 10 Oct 2008 08:18:30 +0100 1871093 http://www.medworm.com/index.php?rid=1871092&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv228636r04322583%2F This article discusses the potential effects the more common headache medications have on weight. Content Type Journal ArticleDOI 10.1007/s11916-008-0035-0Authors William B. Young, Thomas Jefferson University Hospital Jefferson Headache Center, Department of Neurology 111 South Eleventh Street, Suite 8130 Philadelphia PA 19107 USA Journal Current Pain and Headache ReportsOnline ISSN 1534-3081Print ISSN 1531-3433 Journal Volume Volume 12 Journal Issue Volume 12, Number 3 / June, 2008 (Source: Current Pain and Headache Reports) Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1871092 Fri, 10 Oct 2008 08:18:30 +0100 1871092 http://www.medworm.com/index.php?rid=1871091&cid=s_35943_25_f&fid=35943&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd4147313131mqg4t%2F Abstract  Peripheral neuropathies of identical etiology can be painful or painless. The reason for this difference in clinical presentation is as yet unknown; however, immune mediators, particularly cytokines, may play a role. Cytokines are proteins that are produced by immune and nonimmune cells and are categorized as pro-and anti-inflammatory. The role of cytokines in the induction and maintenance of pain has been well established in animal models. Proinflammatory cytokines are mostly algesic, whereas anti-inflammatory cytokines have analgesic properties. Clinical research also gives evidence for the involvement of cytokines in painful and painless neuropathies. A proinflammatory cytokine profile seems to be associated with pain in peripheral neuropathies of different eti... Current Pain and Headache Reports journals http://www.medworm.com/rss/comments.php?id=1871091 Fri, 10 Oct 2008 08:18:30 +0100 1871091