MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Current Problems in Cardiology' source. Sun, 21 Mar 2010 14:01:14 +0100 http://www.medworm.com/index.php?rid=3323876&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001583%2Fabstract%3Frss%3Dyes Abstract: Cardiovascular magnetic resonance provides the opportunity for a truly comprehensive evaluation of patients with a history of myocardial infarction, with regard to characterizing the extent of disease, effect on left ventricular function, and degree of viable myocardium. The use of contrast-enhanced cardiac magnetic resonance (CMR) imaging for first-pass perfusion and late gadolinium enhancement is a powerful technique for delineating areas of myocardial ischemia and infarction. Using a combination of T2-weighted and contrast-enhanced CMR images, information about the acuity of an infarct can be obtained. There is extensive published data using contrast-enhanced CMR to predict myocardial functional recovery with revascularization in patients with ischemic cardiomyopathies. In add... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3323876 Wed, 03 Mar 2010 13:55:05 +0100 3323876 http://www.medworm.com/index.php?rid=3323875&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001571%2Fabstract%3Frss%3Dyes Dr Christopher Kramer is widely recognized as one of the experts in the field. Dr Kramer and his colleague have prepared an important manuscript that covers the role of MRI imaging of myocardial infarction, viability, and cardiomyopathies. It is comprehensive and has 119 physicians taking care of patients with cardiovascular disease. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3323875 Wed, 03 Mar 2010 13:55:05 +0100 3323875 http://www.medworm.com/index.php?rid=3323874&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280610000204%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3323874 Wed, 03 Mar 2010 13:55:05 +0100 3323874 http://www.medworm.com/index.php?rid=3323873&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280610000198%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3323873 Wed, 03 Mar 2010 13:55:05 +0100 3323873 http://www.medworm.com/index.php?rid=3323872&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280610000186%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3323872 Wed, 03 Mar 2010 13:55:05 +0100 3323872 http://www.medworm.com/index.php?rid=3323871&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280610000174%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3323871 Wed, 03 Mar 2010 13:55:05 +0100 3323871 http://www.medworm.com/index.php?rid=3251953&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001479%2Fabstract%3Frss%3Dyes This article reviews the evidence for current antiplatelet agents in ACSs as well as for the newer agents in later phases of clinical testing. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3251953 Tue, 09 Feb 2010 13:53:54 +0100 3251953 http://www.medworm.com/index.php?rid=3251952&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001467%2Fabstract%3Frss%3Dyes Coronary artery thrombus has been known to cause acute myocardial infarction for almost a century. There was a short period in the 1970s when it was considered due to an embolus on the basis of one pathologic study. The emboli theory was never seriously accepted and was completely discarded based on: (1) a study of coronary arteriographic findings and (2) the success of thrombolytic therapy. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3251952 Tue, 09 Feb 2010 13:53:54 +0100 3251952 http://www.medworm.com/index.php?rid=3251951&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS014628061000006X%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3251951 Tue, 09 Feb 2010 13:53:54 +0100 3251951 http://www.medworm.com/index.php?rid=3251950&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280610000058%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3251950 Tue, 09 Feb 2010 13:53:54 +0100 3251950 http://www.medworm.com/index.php?rid=3251949&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280610000046%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3251949 Tue, 09 Feb 2010 13:53:54 +0100 3251949 http://www.medworm.com/index.php?rid=3251948&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280610000034%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3251948 Tue, 09 Feb 2010 13:53:54 +0100 3251948 http://www.medworm.com/index.php?rid=3139941&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001273%2Fabstract%3Frss%3Dyes Abstract: Coronary heart disease (CHD) is the single largest cause of death in the developed countries and is one of the leading causes of disease burden in developing countries. In 2001, there were 7.3 million deaths due to CHD worldwide. Three-fourths of global deaths due to CHD occurred in the low- and middle-income countries. The rapid rise in CHD burden in most of the low- and middle-income countries is due to socio-economic changes, increase in lifespan, and acquisition of lifestyle-related risk factors. The CHD death rate, however, varies dramatically across the developing countries. The varying incidence, prevalence, and mortality rates reflect the different levels of risk factors, other competing causes of death, availability of resources to combat cardiovascular disease, and the ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3139941 Tue, 05 Jan 2010 13:52:46 +0100 3139941 http://www.medworm.com/index.php?rid=3139940&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001261%2Fabstract%3Frss%3Dyes The world has become “small” and “flat.” Financial, environmental, and health issues that occur in many parts of the world are having a significant effect on the way of life in the wealthier and more developed countries, including the USA. These effects will have a much greater impact in the coming years. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3139940 Tue, 05 Jan 2010 13:52:46 +0100 3139940 http://www.medworm.com/index.php?rid=3139939&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001522%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3139939 Tue, 05 Jan 2010 13:52:46 +0100 3139939 http://www.medworm.com/index.php?rid=3139938&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001510%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3139938 Tue, 05 Jan 2010 13:52:46 +0100 3139938 http://www.medworm.com/index.php?rid=3139937&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001509%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3139937 Tue, 05 Jan 2010 13:52:46 +0100 3139937 http://www.medworm.com/index.php?rid=3139936&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001492%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3139936 Tue, 05 Jan 2010 13:52:45 +0100 3139936 http://www.medworm.com/index.php?rid=3057827&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001248%2Fabstract%3Frss%3Dyes Abstract: The prevalence of heart failure is increasing, and the prognosis of end-stage heart failure remains dismal. The gold-standard therapy in end-stage heart failure remains cardiac transplantation at the present time, but there is a great excess of eligible candidates compared with the number of donor organs. Advances in mechanical support, the development of the left ventricular assist device (LVAD), and the total artificial heart has reduced mortality and morbidity in patients awaiting transplantation, and LVADs are now approved as an strategy for destination therapy. Miniaturization, increased device durability, and complete implantability may render LVADs an option in earlier stages of heart failure, as a bridge to myocardial recovery or even as a viable alternative to transplant... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3057827 Sat, 05 Dec 2009 13:50:32 +0100 3057827 http://www.medworm.com/index.php?rid=3057826&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS014628060900125X%2Fabstract%3Frss%3Dyes As our population ages, the prevalence of heart failure is increasing. It has now reached a very high level and affects almost 6 million people. About 300,000 people die of heart failure each year. In the Western world, the most common cause of heart failure is the result of atherosclerotic coronary artery disease. Medical therapy has had a beneficial effect on survival and quality of life in those with mild and moderate heart failure and in the quality of life for those with severe heart failure. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3057826 Sat, 05 Dec 2009 13:50:32 +0100 3057826 http://www.medworm.com/index.php?rid=3057825&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001418%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3057825 Sat, 05 Dec 2009 13:50:32 +0100 3057825 http://www.medworm.com/index.php?rid=3057824&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001406%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3057824 Sat, 05 Dec 2009 13:50:32 +0100 3057824 http://www.medworm.com/index.php?rid=3057823&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS014628060900139X%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3057823 Sat, 05 Dec 2009 13:50:32 +0100 3057823 http://www.medworm.com/index.php?rid=3057822&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001388%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=3057822 Sat, 05 Dec 2009 13:50:32 +0100 3057822 http://www.medworm.com/index.php?rid=2951758&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001145%2Fabstract%3Frss%3Dyes Abstract: No matter how rare, the death of young athletes is a tragedy. Can it be prevented? The European experience suggests that adding the electrocardiogram (ECG) to the standard medical and family history and physical examination can decrease cardiac deaths by 90%. However, there has not been a randomized trial to demonstrate such a reduction. While there are obvious differences between the European and American experiences with athletes including very differing causes of athletic deaths, some would highlight the European emphasis on public welfare vs the protection of personal rights in the USA. Even the authors of this systematic review have differing interpretation of the data: some of us view screening as a hopeless battle against Bayes, while others feel that the ECG can save live... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2951758 Tue, 03 Nov 2009 13:52:09 +0100 2951758 http://www.medworm.com/index.php?rid=2951757&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001133%2Fabstract%3Frss%3Dyes There is general agreement that sudden death occurs in young competitive athletes. More than half of these deaths are due to cardiovascular disease. In Italy, including a 12-lead electrocardiogram in the screening has had spectacular success and reduced sudden death by about 90%. In the USA, for a variety of reasons, including electrocardiogram in the screening process has been debated and is controversial. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2951757 Tue, 03 Nov 2009 13:52:09 +0100 2951757 http://www.medworm.com/index.php?rid=2951756&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001327%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2951756 Tue, 03 Nov 2009 13:52:09 +0100 2951756 http://www.medworm.com/index.php?rid=2951755&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001315%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2951755 Tue, 03 Nov 2009 13:52:09 +0100 2951755 http://www.medworm.com/index.php?rid=2951754&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001303%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2951754 Tue, 03 Nov 2009 13:52:09 +0100 2951754 http://www.medworm.com/index.php?rid=2951753&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001297%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2951753 Tue, 03 Nov 2009 13:52:09 +0100 2951753 http://www.medworm.com/index.php?rid=2860057&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000954%2Fabstract%3Frss%3Dyes Abstract: Worldwide, cardiovascular diseases are among the leading causes of mortality and morbidity with ever-increasing prevalence. Early targeted initiation of preventive measures would be of great benefit and can provide a major opportunity in reducing mortality and morbidity. To this end, accurate identification of individuals who are still asymptomatic but at elevated risk is essential. However, traditional risk assessment fails to recognize a substantial proportion of patients at high risk while a large proportion of individuals are classified as having intermediate risk, leaving management uncertain. Additional strategies to further refine risk assessment are therefore highly needed. To this end, the use of biomarkers and noninvasive imaging modalities has been proposed. The aim of... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2860057 Mon, 05 Oct 2009 16:19:46 +0100 2860057 http://www.medworm.com/index.php?rid=2860056&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000966%2Fabstract%3Frss%3Dyes Modern pharmacologic and revascularization therapies have been remarkably successful in markedly improving patient outcomes. Nevertheless, major untoward events, including myocardial infarction and death, continue to occur in “apparently” healthy people, which frequently are euphemisms of the asymptomatic state. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2860056 Mon, 05 Oct 2009 16:19:46 +0100 2860056 http://www.medworm.com/index.php?rid=2860055&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001194%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2860055 Mon, 05 Oct 2009 16:19:46 +0100 2860055 http://www.medworm.com/index.php?rid=2860054&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001182%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2860054 Mon, 05 Oct 2009 16:19:46 +0100 2860054 http://www.medworm.com/index.php?rid=2860053&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001170%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2860053 Mon, 05 Oct 2009 16:19:46 +0100 2860053 http://www.medworm.com/index.php?rid=2860052&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001169%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2860052 Mon, 05 Oct 2009 16:19:44 +0100 2860052 http://www.medworm.com/index.php?rid=2770851&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS014628060900084X%2Fabstract%3Frss%3Dyes Abstract: Patent foramen ovale has become the subject of increasing interest in modern cardiovascular disease. This has been the result of several factors including, among others, description of paradoxical embolism, documentation of patent foramen ovale with right to left shunt, the rather ubiquitous use of echocardiography, the issue of stroke prevention, and more recently, the relationship between patent foramen ovale and migraine. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2770851 Mon, 07 Sep 2009 16:15:55 +0100 2770851 http://www.medworm.com/index.php?rid=2770850&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000851%2Fabstract%3Frss%3Dyes With the widespread availability and use of echocardiography, the presence of patent foramen ovale (PFO) is being increasingly diagnosed. In step with the diagnosis of the PFO, several associated clinical problems (eg, cryptogenic stroke, migraine) have been recognized. Also, the techniques of percutaneous closure of PFO and of closure devices have been developed. The field has progressed rapidly; as a result, these have become an important part of interventional therapeutic cardiology. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2770850 Mon, 07 Sep 2009 16:15:55 +0100 2770850 http://www.medworm.com/index.php?rid=2770849&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001054%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2770849 Mon, 07 Sep 2009 16:15:55 +0100 2770849 http://www.medworm.com/index.php?rid=2770848&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001042%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2770848 Mon, 07 Sep 2009 16:15:55 +0100 2770848 http://www.medworm.com/index.php?rid=2770847&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001030%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2770847 Mon, 07 Sep 2009 16:15:55 +0100 2770847 http://www.medworm.com/index.php?rid=2770846&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609001029%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2770846 Mon, 07 Sep 2009 16:15:55 +0100 2770846 http://www.medworm.com/index.php?rid=2675952&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000747%2Fabstract%3Frss%3Dyes Abstract: Peripheral arterial disease (PAD) affects about 27 million people in North America and Europe, accounting for up to 413,000 hospitalizations per year with 88,000 hospitalizations involving the lower extremities and 28,000 involving embolectomy or thrombectomy of lower limb arteries. Many patients are asymptomatic and, among symptomatic patients, atypical symptoms are more common than classic claudication. Peripheral arterial disease also correlates strongly with risk of major cardiovascular events, and patients with PAD have a high prevalence of coexistent coronary and cerebrovascular disease. Because the prevalence of PAD increases progressively with age, PAD is a growing clinical problem due to the increasingly aged population in the United States and other developed countries.... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2675952 Fri, 07 Aug 2009 10:45:22 +0100 2675952 http://www.medworm.com/index.php?rid=2675951&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000735%2Fabstract%3Frss%3Dyes Peripheral arterial disease (PAD) affects a very large number of people in the USA and poses a great risk for poor outcomes. There is a strong relationship between PAD and coronary artery disease and between PAD and cerebrovascular disease. The commonly recognized risk factors for coronary artery disease also apply to PAD but smoking and diabetes are particularly high risk factors for PAD. Treatment of all of these risk factors is important. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2675951 Fri, 07 Aug 2009 10:45:22 +0100 2675951 http://www.medworm.com/index.php?rid=2675950&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000905%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2675950 Fri, 07 Aug 2009 10:45:22 +0100 2675950 http://www.medworm.com/index.php?rid=2675949&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000899%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2675949 Fri, 07 Aug 2009 10:45:22 +0100 2675949 http://www.medworm.com/index.php?rid=2675948&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000887%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2675948 Fri, 07 Aug 2009 10:45:22 +0100 2675948 http://www.medworm.com/index.php?rid=2675947&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000875%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2675947 Fri, 07 Aug 2009 10:45:22 +0100 2675947 http://www.medworm.com/index.php?rid=2585701&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000577%2Fabstract%3Frss%3Dyes Abstract: Cardiogenic shock (CS) may result from ischemic heart disease, cardiomyopathy, valvular heart disease, inflammation, myocardial contusion, and cardiac surgery. CS is the leading cause of in-hospital death in patients with acute myocardial infarction. Although early revascularization strategies have resulted in a better prognosis, in-hospital mortality from CS remains exceptionally high. Notably, long-term annual mortality is similar in survivors of CS relative to patients with myocardial infarction without shock. This underlines the importance of aggressive support of the failing heart in the acute phase of CS. Because CS reflects a state of hypoperfusion induced by heart failure, management of CS should aim at improving cardiac function as well as at optimization of tissue perfu... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2585701 Fri, 10 Jul 2009 10:44:24 +0100 2585701 http://www.medworm.com/index.php?rid=2585700&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000565%2Fabstract%3Frss%3Dyes There has been a remarkable reduction in the incidence of cardiogenic shock due to acute myocardial infarction in patients admitted to the hospital. Up until the early 1970s we would see up to 2 to 3 such cases each week. Then, we progressively saw fewer cases of cardiogenic shock. This coincided with widespread performance of coronary artery bypass graft surgery and, over the subsequent 30 years, cardiogenic shock has become decidedly uncommon. This also coincided with performance of percutaneous coronary interventions and also the availability of modern pharmacologic therapy. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2585700 Fri, 10 Jul 2009 10:44:24 +0100 2585700 http://www.medworm.com/index.php?rid=2585699&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000796%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2585699 Fri, 10 Jul 2009 10:44:24 +0100 2585699 http://www.medworm.com/index.php?rid=2585698&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000784%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2585698 Fri, 10 Jul 2009 10:44:24 +0100 2585698 http://www.medworm.com/index.php?rid=2585697&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000772%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2585697 Fri, 10 Jul 2009 10:44:24 +0100 2585697 http://www.medworm.com/index.php?rid=2585696&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000760%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2585696 Fri, 10 Jul 2009 10:44:24 +0100 2585696 http://www.medworm.com/index.php?rid=2459379&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000309%2Fabstract%3Frss%3Dyes This article, while not intended to be a comprehensive collection, aims to serve as an introduction to the current applications of cardiac MRI. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2459379 Sun, 07 Jun 2009 17:13:37 +0100 2459379 http://www.medworm.com/index.php?rid=2459378&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000292%2Fabstract%3Frss%3Dyes Medicine, and especially cardiovascular medicine, has been blessed with the emergence of many new diagnostic modalities that are becoming an integral part of management strategies to take care of our patients. As a result, it has become vital and essential for clinicians taking care of such patients to be very knowledgeable of these images. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2459378 Sun, 07 Jun 2009 17:13:37 +0100 2459378 http://www.medworm.com/index.php?rid=2459377&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000632%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2459377 Sun, 07 Jun 2009 17:13:37 +0100 2459377 http://www.medworm.com/index.php?rid=2459376&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000620%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2459376 Sun, 07 Jun 2009 17:13:37 +0100 2459376 http://www.medworm.com/index.php?rid=2459375&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000619%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2459375 Sun, 07 Jun 2009 17:13:37 +0100 2459375 http://www.medworm.com/index.php?rid=2459374&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000607%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2459374 Sun, 07 Jun 2009 17:13:37 +0100 2459374 http://www.medworm.com/index.php?rid=2399719&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000140%2Fabstract%3Frss%3Dyes This article reviews general indications for cardiac CT imaging. Common variants and pathologies of the cardiovascular system are illustrated by clinical examples. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2399719 Sun, 10 May 2009 15:51:38 +0100 2399719 http://www.medworm.com/index.php?rid=2399718&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000474%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2399718 Sun, 10 May 2009 15:51:38 +0100 2399718 http://www.medworm.com/index.php?rid=2399717&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000139%2Fabstract%3Frss%3Dyes Medicine, and especially cardiovascular medicine, has been blessed with the emergence of many new diagnostic modalities that are becoming an integral part of management strategies to take care of our patients. As a result, it has become vital and essential for clinicians taking care of such patients to be very knowledgeable of these images. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2399717 Sun, 10 May 2009 15:51:38 +0100 2399717 http://www.medworm.com/index.php?rid=2399716&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000462%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2399716 Sun, 10 May 2009 15:51:38 +0100 2399716 http://www.medworm.com/index.php?rid=2399715&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000450%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2399715 Sun, 10 May 2009 15:51:38 +0100 2399715 http://www.medworm.com/index.php?rid=2399714&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000449%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2399714 Sun, 10 May 2009 15:51:37 +0100 2399714 http://www.medworm.com/index.php?rid=2399713&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000437%2Fabstract%3Frss%3Dyes (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2399713 Sun, 10 May 2009 15:51:37 +0100 2399713 http://www.medworm.com/index.php?rid=2350128&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000127%2Fabstract%3Frss%3Dyes Abstract: Patients with scar-related ventricular tachycardia (VT) are subject to frequent arrhythmia recurrences; antiarrhythmic drug therapy has been disappointing due to poor efficacy and side effects. Patients receiving multiple implantable cardioverter-defibrillator shocks because of VT have impaired quality of life. The role of catheter ablation in the treatment of ventricular arrhythmias has been increasing in the last 2 decades. As more knowledge is gained about the mechanisms of VT, the potential for doing ablation has increased. Now, multiple VTs and unstable VTs can be targeted by ablation strategies. Also, electroanatomic mapping systems have made substrate mapping feasible. The purpose of this article is to review the selection and preparation of patients who require catheter a... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2350128 Tue, 21 Apr 2009 07:19:38 +0100 2350128 http://www.medworm.com/index.php?rid=2350127&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.cpcardiology.com%2Farticle%2FPIIS0146280609000115%2Fabstract%3Frss%3Dyes Scar-related ventricular tachycardia is most commonly associated with previous myocardial infarction. There are other causes, for example, arrhythmogenic right ventricular dysplasia. Such patients have frequent arrhythmias. Pharmacologic therapy has not been very efficacious and drug-related side effects are common. (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2350127 Tue, 21 Apr 2009 07:19:37 +0100 2350127 http://www.medworm.com/index.php?rid=2251016&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19269526%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 19269526 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2251016 Wed, 11 Mar 2009 10:32:25 +0100 2251016 http://www.medworm.com/index.php?rid=2251013&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19269527%26dopt%3DAbstract Authors: Kantor B, Nagel E, Schoenhagen P, Barkhausen J, Gerber TC Cardiac computed tomography and magnetic resonance are relatively new imaging modalities that can exceed the ability of established imaging modalities to detect present pathology or predict patient outcomes. Coronary calcium scoring may be useful in asymptomatic patients at intermediate risk. Computed tomographic coronary angiography is a first-line indication to evaluate congenitally abnormal coronary arteries and, along with stress magnetic resonance myocardial perfusion imaging, is useful in symptomatic patients with nondiagnostic conventional stress tests. Cardiac magnetic resonance is indicated for visualizing cardiac structure and function, and delayed enhancement magnetic resonance is a first-line indication for ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2251013 Wed, 11 Mar 2009 10:30:43 +0100 2251013 http://www.medworm.com/index.php?rid=2216617&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19232243%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 19232243 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2216617 Thu, 26 Feb 2009 17:41:43 +0100 2216617 http://www.medworm.com/index.php?rid=2210534&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19232243%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 19232243 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2210534 Wed, 25 Feb 2009 00:55:16 +0100 2210534 http://www.medworm.com/index.php?rid=2210533&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19232244%26dopt%3DAbstract Authors: Ahmed MI, McGiffin DC, O'Rourke RA, Dell'italia LJ Mitral regurgitation (MR) is increasingly prevalent and poses an important public health problem. There are several mechanisms through which MR can occur. Primary (organic) MR is due to intrinsic valvular disease, whereas secondary (functional) MR is due to disruption of an otherwise normal mitral apparatus because of abnormal ventricular geometry. Identification of the causative mechanism is important as this will dictate management strategy and may influence subsequent outcome. Careful assessment of MR severity is important with the use of quantitative measures. There is currently no effective medical treatment for chronic MR. Careful follow-up is paramount in the management of MR to accomplish timely surgical intervention. ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2210533 Wed, 25 Feb 2009 00:55:11 +0100 2210533 http://www.medworm.com/index.php?rid=2104518&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19135615%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 19135615 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2104518 Thu, 15 Jan 2009 08:39:06 +0100 2104518 http://www.medworm.com/index.php?rid=2100957&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19135615%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 19135615 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2100957 Wed, 14 Jan 2009 07:50:12 +0100 2100957 http://www.medworm.com/index.php?rid=2100956&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19135616%26dopt%3DAbstract Authors: Gaddam KK, Pimenta E, Husain S, Calhoun DA Aldosterone is an adrenal hormone that regulates sodium, fluid, and potassium balance. Jerome Conn first described the syndrome of autonomous and excessive aldosterone secretion or "primary aldosteronism." Contrary to the historical belief, recent studies indicate that primary aldosteronism is a common cause of hypertension with a prevalence of 5-10% among general hypertensive patients. Various animal models have demonstrated that aldosterone in association with a high salt diet results in target-organ inflammation and fibrosis. Similarly, cross-sectional and observational human studies have demonstrated the association of aldosterone with development and severity of hypertension, congestive heart failure, coronary artery disease, chr... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2100956 Wed, 14 Jan 2009 07:50:09 +0100 2100956 http://www.medworm.com/index.php?rid=2033166&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19068245%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 19068245 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2033166 Sat, 13 Dec 2008 09:57:29 +0100 2033166 http://www.medworm.com/index.php?rid=2033165&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19068246%26dopt%3DAbstract Authors: Katz G, Arad M, Eldar M Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a primary electrical myocardial disease characterized by exercise- and stress-related ventricular tachycardia manifested as syncope and sudden death. The disease has a heterogeneous genetic basis, with mutations in the cardiac Ryanodine Receptor channel (RyR2) gene accounting for an autosomal-dominant form (CPVT1) in approximately 50% and mutations in the cardiac calsequestrin gene (CASQ2) accounting for an autosomal-recessive form (CPVT2) in up to 2% of CPVT cases. Both RyR2 and calsequestrin are important participants in the cardiac cellular calcium homeostasis. We review the physiology of the cardiac calcium homeostasis, including the cardiac excitation contraction coupling and myocyte c... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=2033165 Sat, 13 Dec 2008 09:57:25 +0100 2033165 http://www.medworm.com/index.php?rid=1960711&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19000585%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 19000585 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1960711 Sat, 15 Nov 2008 10:13:53 +0100 1960711 http://www.medworm.com/index.php?rid=1960710&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19000586%26dopt%3DAbstract Authors: Faulx MD, Francis GS Adverse drug reactions (ADRs) occur frequently in modern medical practice, increasing morbidity and mortality and inflating the cost of care. Patients with cardiovascular disease are particularly vulnerable to ADRs due to their advanced age, polypharmacy, and the influence of heart disease on drug metabolism. The ADR potential for a particular cardiovascular drug varies with the individual, the disease being treated, and the extent of exposure to other drugs. Knowledge of this complex interplay between patient, drug, and disease is a critical component of safe and effective cardiovascular disease management. The majority of significant ADRs involving cardiovascular drugs are predictable and therefore preventable. Better patient education, avoidance of poly... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1960710 Sat, 15 Nov 2008 10:13:46 +0100 1960710 http://www.medworm.com/index.php?rid=1859528&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18835465%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18835465 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1859528 Wed, 08 Oct 2008 12:55:16 +0100 1859528 http://www.medworm.com/index.php?rid=1859527&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18835466%26dopt%3DAbstract Authors: Goldenberg I, Zareba W, Moss AJ The hereditary Long QT syndrome (LQTS) is a genetic channelopathy with variable penetrance that is associated with increased propensity for polymorphic ventricular tachyarrhythmias and sudden cardiac death in young individuals with normal cardiac morphology. The diagnosis of this genetic disorder relies on a constellation of electrocardiographic, clinical, and genetic factors. Accumulating data from recent studies indicate that the clinical course of affected LQTS patients is time-dependent and age-specific, demonstrating important gender differences among age groups. Risk assessment should consider age-gender interactions, prior syncopal history, QT-interval duration, and genetic factors. Beta-blockers constitute the mainstay therapy for LQTS, ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1859527 Wed, 08 Oct 2008 12:55:05 +0100 1859527 http://www.medworm.com/index.php?rid=1779242&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18772054%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18772054 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1779242 Wed, 10 Sep 2008 11:12:34 +0100 1779242 http://www.medworm.com/index.php?rid=1770470&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18772054%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18772054 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1770470 Sun, 07 Sep 2008 10:33:39 +0100 1770470 http://www.medworm.com/index.php?rid=1770469&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18772055%26dopt%3DAbstract Authors: Lee KW, Badhwar N, Scheinman MM Supraventricular tachycardias (SVTs) affect all age groups and are a source of significant morbidity. They are frequently encountered in otherwise healthy individuals without structural heart disease. Advances in the understanding of their mechanisms and anatomical locations have led to highly effective pharmacologic and nonpharmacologic treatment strategies. Recognition, identification, and differentiation of the various SVTs are of great importance in formulating an effective treatment strategy. Developments over the past four decades have made possible the accurate diagnosis of SVTs, and technological advances have led to ablative cures of most of these arrhythmias. This monograph provides an in-depth discussion of the history, presentation, ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1770469 Sun, 07 Sep 2008 10:33:36 +0100 1770469 http://www.medworm.com/index.php?rid=1717175&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18707989%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18707989 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1717175 Wed, 20 Aug 2008 10:28:27 +0100 1717175 http://www.medworm.com/index.php?rid=1717174&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18707990%26dopt%3DAbstract Authors: Lee KW, Badhwar N, Scheinman MM Supraventricular tachycardias (SVTs) affect all age groups and are a source of significant morbidity. They are frequently encountered in otherwise healthy individuals without structural heart disease. Advances in the understanding of their mechanisms and anatomical locations have led to highly effective pharmacologic and nonpharmacologic treatment strategies. Recognition, identification, and differentiation of the various SVTs are of great importance in formulating an effective treatment strategy. Developments over the past four decades have made possible the accurate diagnosis of SVTs. Today, advances in catheter design, energy delivery systems, mapping systems, and remote navigation systems have rendered the ablation of most SVTs safe and effe... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1717174 Wed, 20 Aug 2008 10:28:25 +0100 1717174 http://www.medworm.com/index.php?rid=1631066&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18620098%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18620098 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1631066 Thu, 17 Jul 2008 10:42:33 +0100 1631066 http://www.medworm.com/index.php?rid=1631065&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18620099%26dopt%3DAbstract Authors: Tops LF, Kapadia SR, Tuzcu EM, Vahanian A, Alfieri O, Webb JG, Bax JJ Valvular heart disease is an important cause of morbidity and mortality. Aortic stenosis and mitral regurgitation account for the majority of patients with native valve disease. Although surgical treatment provides satisfactory outcome, a large proportion of patients do not undergo a surgical intervention, because of the high estimated operative risk and multiple comorbidities. Recently, new techniques that enable percutaneous treatment of valvular heart disease have been developed and their feasibility has been reported in several studies. All techniques target a minimal invasive procedure with a low risk of procedure-related complications. In this article, an overview of the various percutaneous procedures... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1631065 Thu, 17 Jul 2008 10:42:29 +0100 1631065 http://www.medworm.com/index.php?rid=1554435&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18513576%26dopt%3DAbstract Authors: O'Rourke RA PMID: 18513576 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1554435 Mon, 30 Jun 2008 09:42:02 +0100 1554435 http://www.medworm.com/index.php?rid=1488225&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18513576%26dopt%3DAbstract Authors: O'Rourke RA PMID: 18513576 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1488225 Tue, 03 Jun 2008 18:18:10 +0100 1488225 http://www.medworm.com/index.php?rid=1488224&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18513577%26dopt%3DAbstract Authors: Chizner MA Cardiac auscultation, long considered the centerpiece of the cardiac clinical examination, is rapidly becoming a lost art. Inadequate emphasis on the essentials of cardiac auscultation has resulted from the widespread availability of more elaborate and expensive "high-tech" diagnostic and therapeutic methods, particularly Doppler echocardiography. However, sophisticated high technology is not a substitute for a solid foundation in clinical cardiology including cardiac auscultation. When used properly, the stethoscope remains a valuable and cost-effective clinical tool that often enables many well-trained and experienced cardiac auscultators to make a rapid and accurate cardiac diagnosis with fewer, if any, additional studies. Not every patient needs every test. Acco... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1488224 Tue, 03 Jun 2008 18:18:06 +0100 1488224 http://www.medworm.com/index.php?rid=1426370&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18457716%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18457716 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1426370 Wed, 07 May 2008 21:55:50 +0100 1426370 http://www.medworm.com/index.php?rid=1426369&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18457717%26dopt%3DAbstract Authors: Yang EH, Holmes DR Stroke is one of the leading causes of morbidity and mortality in the United States. Approximately 700,000 Americans suffer from a stroke per year and 270,000 of these patients will die as a result of their stroke. The etiology of cerebrovascular events can be attributed to carotid artery disease in 20-30% of cases. Carotid endarterectomy has been shown to be beneficial in selected patients with symptomatic and asymptomatic carotid artery stenosis. Percutaneous treatment of carotid disease appears to be effective when performed with distal protection by an experienced operator. This review presents the clinical trial data regarding surgical and percutaneous management of carotid disease. PMID: 18457717 [PubMed - in process] (Source: Current Problems in C... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1426369 Wed, 07 May 2008 21:55:47 +0100 1426369 http://www.medworm.com/index.php?rid=1406994&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18439438%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18439438 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1406994 Tue, 29 Apr 2008 21:03:11 +0100 1406994 http://www.medworm.com/index.php?rid=1406993&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18439439%26dopt%3DAbstract Authors: Elefteriades JA The vast database of the Yale Center for Thoracic Aortic Disease-which includes information on 3000 patients with thoracic aortic aneurysm or dissection, with 9000 catalogued images and 9000 patient-years of follow-up-has, over the last decade, permitted multiple glimpses into the "playbook" of this virulent disease. Understanding the precise behavioral features of thoracic aortic aneurysm and dissection permits us more effectively to combat this disease. In this monograph, we will first review certain fundamentals-in terms of anatomy, nomenclature, imaging, diagnosis, medical, surgical, and stent treatment. After reviewing these fundamentals, we will proceed with a detailed exploration of lessons learned by peering into the operational playbook of thoracic aor... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1406993 Tue, 29 Apr 2008 21:03:07 +0100 1406993 http://www.medworm.com/index.php?rid=1406992&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18439440%26dopt%3DAbstract Authors: PMID: 18439440 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1406992 Tue, 29 Apr 2008 21:03:05 +0100 1406992 http://www.medworm.com/index.php?rid=1283467&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18319101%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18319101 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1283467 Thu, 06 Mar 2008 21:05:33 +0100 1283467 http://www.medworm.com/index.php?rid=1283466&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18319102%26dopt%3DAbstract Authors: Yusuf SW, Razeghi P, Yeh ET Cardiovascular disease is commonly found in cancer patients. The co-existence of heart disease and cancer in a patient often complicates treatment, because therapy for one disease may negatively affect the outcome of the other disease. In addition, guidelines for the treatment of cardiovascular disease are often based on studies, which exclude patients who have cancer. In this review we will discuss the diagnosis and management of cardiovascular disease in cancer patients. We will focus on cancer-related causes of cardiovascular disease and special treatment options for cardiovascular disease in cancer patients. The cardiac complications of cancer therapy will be discussed according to common syndromes: left ventricular dysfunction, myocardial ische... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1283466 Thu, 06 Mar 2008 21:05:31 +0100 1283466 http://www.medworm.com/index.php?rid=1207378&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18243901%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18243901 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1207378 Wed, 06 Feb 2008 09:17:55 +0100 1207378 http://www.medworm.com/index.php?rid=1207377&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18243902%26dopt%3DAbstract Authors: Leri A, Kajstura J, Anversa P, Frishman WH Recent evidence would suggest that the heart is not a terminally differentiated organ and has the ability to regenerate itself under normal and pathophysiologic conditions. A major effort has been made to identify precursor cells that are capable of differentiating into cell lineages different from their organ of origin. Embryonic stem cells and bone marrow-derived cells (BMCs) have been studied and characterized, and BM precursor cells are currently being utilized as therapy in clinical trials of patients with heart failure of ischemic and nonischemic etiologies. Controversy remains, however, whether BMCs are the best cells to be used for replacement therapy. The existence of a cardiac stem cell (CSC) has also been described, which h... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1207377 Wed, 06 Feb 2008 09:17:53 +0100 1207377 http://www.medworm.com/index.php?rid=1185768&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18222316%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18222316 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1185768 Tue, 29 Jan 2008 21:05:29 +0100 1185768 http://www.medworm.com/index.php?rid=1185767&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18222317%26dopt%3DAbstract Authors: Shah PM, Raney AA The normal tricuspid valve anatomy and function have several dissimilarities to the corresponding mitral valve in the left heart, in part, based on lower pressures in the right heart chambers. The functional abnormalities resulting from tricuspid valve disease are classified as primary and secondary. Primary valve disease is any associated intrinsic valve pathology. The list of responsible conditions includes congenital, rheumatic, infective endocarditis, carcinoid heart disease, toxic effects of chemicals, tumors, blunt trauma, and myxomatous degeneration. The secondary tricuspid valve disease does not involve intrinsic anatomic abnormalities of the valve apparatus, aside from tricuspid annular dilation secondary to right ventricular dilation and dysfunction... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1185767 Tue, 29 Jan 2008 21:05:27 +0100 1185767 http://www.medworm.com/index.php?rid=1116144&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18155513%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18155513 [PubMed - as supplied by publisher] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1116144 Wed, 26 Dec 2007 01:52:35 +0100 1116144 http://www.medworm.com/index.php?rid=1116143&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18155514%26dopt%3DAbstract Authors: Ammash NM, Sundt TM, Connolly HM Marfan syndrome (MFS) is the most common inherited disorder of connective tissue that affects multiple organ systems. This autosomal-dominant condition has an incidence of 2-3 per 10,000 individuals. Although genetic testing is available, the diagnosis is still primarily made using the Ghent criteria. Early identification and appropriate management is critical for patients with MFS who are prone to the life-threatening cardiovascular complications of aortic dissection and rupture. Advances in the understanding of the cause of MFS, early recognition of the disorder, and subsequent institution of medical and surgical therapy has resulted in dramatic improvement in the prognosis of this patient population over the past few decades. Beta-blockers h... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1116143 Wed, 26 Dec 2007 01:52:33 +0100 1116143 http://www.medworm.com/index.php?rid=1052300&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18037086%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 18037086 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1052300 Tue, 27 Nov 2007 14:24:46 +0100 1052300 http://www.medworm.com/index.php?rid=1052299&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18037087%26dopt%3DAbstract Authors: Sra J, Akhtar M Atrial fibrillation (AF) is a common arrhythmia. Although significant work still needs to be done, recent advances in understanding the mechanism of AF have led to the development of elegant catheter mapping techniques for ablation of AF. These improved mapping techniques are complemented by an evolution in various imaging and navigational technologies, several of which can now be combined in a process called registration, so that the physician no longer needs to rely solely on a mental image of the anatomy of the left atrium and the pulmonary vein while attempting to ablate the region. Ongoing advances in mapping technique will increase safety and efficacy and it is likely that AF ablation will become the first-line therapy in most patients with this complicat... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1052299 Tue, 27 Nov 2007 14:24:44 +0100 1052299 http://www.medworm.com/index.php?rid=1001641&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17976509%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17976509 [PubMed - as supplied by publisher] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1001641 Thu, 01 Nov 2007 04:00:00 +0100 1001641 http://www.medworm.com/index.php?rid=1001640&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17976510%26dopt%3DAbstract Authors: Iung B, Baron G, Tornos P, Gohlke-Bärwolf C, Butchart EG, Vahanian A The Euro Heart Survey on valvular heart disease included 5001 patients from 92 centers in 25 European countries in 2001: 71.9% had native valve disease and 28.1% had previously undergone valve surgery. Aortic stenosis (AS) and mitral regurgitation (MR) accounted for 43.1 and 33.6%, respectively, of single-valve diseases and were mostly caused by degenerative diseases. Mean age was 69 and 65 years, respectively, and at least one comorbidity was present in 36.3% of patients with AS and 41.7% with MR. Analysis of the therapeutic decision in patients with severe valve diseases showed that symptomatic patients were frequently denied surgery (32.3% in AS after the age of 75 and 51.3% in MR), more on the basis ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=1001640 Thu, 01 Nov 2007 04:00:00 +0100 1001640 http://www.medworm.com/index.php?rid=936805&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17920923%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17920923 [PubMed - as supplied by publisher] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=936805 Mon, 01 Oct 2007 04:00:00 +0100 936805 http://www.medworm.com/index.php?rid=936804&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17920924%26dopt%3DAbstract Authors: Blom AS, Acker MA Cardiac failure remains the leading cause of death in the Western World today. After myocardial insult, as the heart remodels and dilates, an increase in wall tension occurs secondary to increased radius of curvature, leading to increased myocardial oxygen consumption, decreased subendocardial blood flow, impaired energetics, and increased arrhythmias. Poor prognosis directly correlates with the degree of remodeling. Despite improvements in left ventricular function and long-term outcomes seen with pharmacologic therapy, the results remain far from perfect and the mortality continues to be high. The surgical armamentarium for treating end-stage heart failure is broad and new types of surgical treatments continue to emerge as alternatives to cardiac transplant... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=936804 Mon, 01 Oct 2007 04:00:00 +0100 936804 http://www.medworm.com/index.php?rid=828103&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17723905%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17723905 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=828103 Wed, 29 Aug 2007 13:46:17 +0100 828103 http://www.medworm.com/index.php?rid=828102&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17723906%26dopt%3DAbstract Authors: Turakhia M, Tseng ZH Sudden cardiac death is a major public health problem affecting 500,000 patients annually in the United States alone. The major risk factor for sudden cardiac death is the presence of coronary artery disease, usually in the setting of reduced ejection fraction. Globally, the incidence is expected to rise sharply as the prevalence of coronary artery disease and heart failure continue to increase. However, sudden cardiac death is a heterogeneous condition and may be caused by acute ischemia, structural defects, myocardial scar, and/or genetic mutations. Sudden death may occur even in a grossly normal heart. Beta-blockers can reduce the risk of sudden cardiac death, while implantable cardioverter defibrillators are effective at terminating malignant arrhythmi... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=828102 Wed, 29 Aug 2007 13:46:16 +0100 828102 http://www.medworm.com/index.php?rid=752831&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17643824%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17643824 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=752831 Tue, 24 Jul 2007 13:39:54 +0100 752831 http://www.medworm.com/index.php?rid=752830&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17643825%26dopt%3DAbstract Authors: Hameed AB, Sklansky MS Cardiac disorders complicate less than 1% of all pregnancies. Physiologic changes in pregnancy may mimic heart disease. In order to differentiate these adaptations from pathologic conditions, an in-depth knowledge of cardiovascular physiology is mandatory. A comprehensive history, physical examination, electrocardiogram, chest radiograph, and echocardiogram are sufficient in most cases to confirm the diagnosis. Care of women with cardiac disease begins with preconception counseling. Severe lesions should be taken care of prior to contemplating pregnancy. Management principles for pregnant women are similar to those for the non-pregnant state. A team approach comprised of a maternal fetal medicine specialist, cardiologist, neonatologist, and anesthesiolog... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=752830 Tue, 24 Jul 2007 13:39:53 +0100 752830 http://www.medworm.com/index.php?rid=675643&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17560991%26dopt%3DAbstract Authors: O'rourke RA PMID: 17560991 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=675643 Sun, 17 Jun 2007 10:06:21 +0100 675643 http://www.medworm.com/index.php?rid=675642&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17560992%26dopt%3DAbstract Authors: Schinkel AF, Bax JJ, Poldermans D, Elhendy A, Ferrari R, Rahimtoola SH Approximately 50% of the patients with chronic obstructive coronary artery disease resulting in chronic contractile dysfunction have hibernating myocardium and may benefit from revascularization. This pooled analysis describes the relative merits of dobutamine echocardiography, thallium-201 and technetium-99m scintigraphy, positron emission tomography, and magentic resonance imaging, for the diagnosis of hibernating myocardium and prediction of patient outcomes. PMID: 17560992 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=675642 Sun, 17 Jun 2007 10:06:21 +0100 675642 http://www.medworm.com/index.php?rid=650988&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17531902%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17531902 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=650988 Fri, 01 Jun 2007 04:00:00 +0100 650988 http://www.medworm.com/index.php?rid=650987&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17531903%26dopt%3DAbstract Authors: Dec GW Acute decompensated heart failure is the most common cause for hospitalization among patients over 65 years of age. It may result from new onset of ventricular dysfunction or, more typically, exacerbation of chronic heart failure symptoms. In-hospital mortality remains high for both systolic and diastolic forms of the disease. Therapy is largely empirical as few randomized, controlled trials have focused on this population and consensus practice guidelines are just beginning to be formulated. Treatment should be focused upon correction of volume overload, identifying potential precipitating causes, and optimizing vasodilator and beta-adrenergic blocker therapy. The majority of patients (>90%) will improve without the use of positive inotropic agents, which should be ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=650987 Fri, 01 Jun 2007 04:00:00 +0100 650987 http://www.medworm.com/index.php?rid=600381&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17481992%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17481992 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=600381 Tue, 01 May 2007 04:00:00 +0100 600381 http://www.medworm.com/index.php?rid=600380&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17481993%26dopt%3DAbstract Authors: Link JJ, Rohatgi A, de Lemos JA Numerous epidemiological studies have identified high-density lipoprotein cholesterol (HDL) to be an independent risk factor for coronary heart disease (CHD). HDL is an emerging therapeutic target that could rival the impact of 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) on LDL and CHD risk reduction. HDL metabolism, HDL kinetics, the concentration of various HDL subclasses, and other genetic factors affecting HDL functionality may all contribute to the anti-atherogenic properties of HDL; thus, standard plasma measurement may not capture the full range of HDL effects. Algorithms have been suggested to treat low HDL levels in subgroups of patients; however, no formal HDL target goals or treatment guidelines have been ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=600380 Tue, 01 May 2007 04:00:00 +0100 600380 http://www.medworm.com/index.php?rid=561251&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17398314%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17398314 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561251 Sun, 01 Apr 2007 04:00:00 +0100 561251 http://www.medworm.com/index.php?rid=561249&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17398315%26dopt%3DAbstract Authors: Elliott WJ Hypertension is a growing public health problem worldwide. Only 37% of American hypertensives currently have their blood pressures controlled. Hypertension is traditionally diagnosed in the medical office, but both home and ambulatory blood pressure monitoring can help. Lifestyle modifications are recommended for everyone who has higher than "normal" blood pressure (<120/80 mm Hg). Voluminous clinical trial data support beginning drug therapy with low-dose chlorthalidone, unless the patient has a specific indication for a different drug. Additional drugs (typically in the sequence, angiotensin converting-enzyme inhibitor or angiotensin receptor blocker, calcium antagonist, beta-blocker, alpha-blocker, aldosterone antagonist, direct vasodilator, and centrally acti... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561249 Sun, 01 Apr 2007 04:00:00 +0100 561249 http://www.medworm.com/index.php?rid=561256&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17382833%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 17382833 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561256 Thu, 01 Mar 2007 05:00:00 +0100 561256 http://www.medworm.com/index.php?rid=561253&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17382834%26dopt%3DAbstract Authors: El-Menyar AA, Al Suwaidi J, Holmes DR Patients with stenosis of the left main coronary artery present difficult challenges. The risks associated with this lesion have been known since the early days of angiography when patients were found to have increased mortality during follow-up. This information led to the general guidelines that surgical revascularization should be considered the treatment of choice in patients with significant left main coronary artery stenosis. Current advances in invasive cardiology have brought important information to the field. Intravascular ultrasound is now used routinely to evaluate angiographically indeterminate lesions with criteria now set forward as to what constitutes an indication for revascularization. Stents have even further dramaticall... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561253 Thu, 01 Mar 2007 05:00:00 +0100 561253 http://www.medworm.com/index.php?rid=561258&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17208647%26dopt%3DAbstract Authors: Kaufmann BA, Wei K, Lindner JR Myocardial contrast echocardiography (MCE) is a noninvasive imaging technique that relies on the ultrasound detection of microbubble contrast agents. These agents are confined to the intravascular space thereby producing signal enhancement from the blood pool. This review encompasses many of the key concepts regarding the clinical application of MCE. The first section focuses on the composition, safety, and biokinetics of ultrasound contrast agents. Then we discuss new ultrasound imaging methodology that has been developed to enhance detection of contrast agent and to assess perfusion at the tissue level. Next, the clinical applications of contrast ultrasound are reviewed. These include enhancement of the cardiac chambers for better assessment of... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561258 Thu, 01 Feb 2007 05:00:00 +0100 561258 http://www.medworm.com/index.php?rid=561259&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17197289%26dopt%3DAbstract Authors: Badhwar N, Scheinman MM Idiopathic ventricular tachycardia (VT) is an uncommon form of VT that is seen in patients without structural heart disease. It is commonly seen in young patients and usually has a benign course. Recent studies have delineated the mechanisms and anatomical locations of this form of VT. Recognition of various forms of idiopathic VT based on characteristic QRS morphology from the 12-lead electrocardiogram (ECG) has important prognostic and therapeutic implications. The understanding of the mechanisms of idiopathic VT has led to the use of specific antiarrhythmic drugs targeting particular arrhythmias. Recent technological advances in the field of mapping and catheter ablation have led to a suitable alternative to drug therapy with a very high cure rate. T... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561259 Mon, 01 Jan 2007 05:00:00 +0100 561259 http://www.medworm.com/index.php?rid=561261&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17097446%26dopt%3DAbstract Authors: Yang EH, Brilakis ES, Reeder GS, Gersh BJ Acute myocardial infarction (AMI) is a subset of the acute coronary syndromes and can be classified as being either a ST-segment elevation myocardial infarction (STEMI) or a non-ST-elevation myocardial infarction (NSTEMI). A clear distinction between STEMI and NSTEMI is essential because of the differences in management. The purpose of this review was to first discuss the epidemiology, pathophysiology, and diagnosis of AMI. The risk stratification and therapy of patients with STEMI and NSTEMI will then be reviewed as well as the complications of AMI. PMID: 17097446 [PubMed - indexed for MEDLINE] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561261 Fri, 01 Dec 2006 05:00:00 +0100 561261 http://www.medworm.com/index.php?rid=561262&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D17052478%26dopt%3DAbstract Authors: Allaqaband S, Solis J, Kazemi S, Bajwa T, , An estimated 10 million people in the U.S. have symptomatic peripheral arterial disease (PAD); 20 to 30 million have asymptomatic PAD. The prevalence of intermittent claudication increases with age, affecting >5% of patients over 70. The incidence of claudication doubles or triples in patients with diabetes. As people grow older, symptoms from peripheral vascular disease increasingly limit daily activity. Until recently, vascular surgical procedures were the only alternative to medical therapy in such patients. Today, advances in minimally invasive percutaneous interventions have made endovascular procedures the primary modality for revascularization in most patients. Compared with open surgical procedures, endovascular intervent... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561262 Wed, 01 Nov 2006 05:00:00 +0100 561262 http://www.medworm.com/index.php?rid=561263&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16962416%26dopt%3DAbstract Authors: Roberts R, Gollob M The terminology and technology of molecular genetics and recombinant DNA have become an essential part of academic cardiology and will soon be applied at the bedside. The treatise includes a brief summary of the essentials of the DNA molecule, the more common techniques, and their application to genetics and molecular cardiology. It is written to be understood by physicians, scientists, and paramedical personnel who would not necessarily have a background in molecular biology. Inherent in the DNA molecule are three properties fundamental to all of the diagnostic and therapeutic applications, namely, the ability of DNA to separate into single strands, recombine (annealment or hybridization), and the presence of the negative charge enables DNA fragments to be... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561263 Sun, 01 Oct 2006 04:00:00 +0100 561263 http://www.medworm.com/index.php?rid=561265&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16935693%26dopt%3DAbstract Authors: Rahimtoola SH PMID: 16935693 [PubMed - in process] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561265 Fri, 01 Sep 2006 04:00:00 +0100 561265 http://www.medworm.com/index.php?rid=561264&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16935694%26dopt%3DAbstract Authors: Russell RR, Zaret BL Nuclear cardiology has made significant advances since the first reports of planar scintigraphy for the evaluation of left ventricular perfusion and function. While the current "state of the art" of gated myocardial perfusion single-photon emission computed tomographic (SPECT) imaging offers invaluable diagnostic and prognostic information for the evaluation of patients with suspected or known coronary artery disease (CAD), advances in the cellular and molecular biology of the cardiovascular system have helped to usher in a new modality in nuclear cardiology, namely, molecular imaging. In this review, we will discuss the current state of the art in nuclear cardiology, which includes SPECT and positron emission tomographic evaluation of myocardial perfusion... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561264 Fri, 01 Sep 2006 04:00:00 +0100 561264 http://www.medworm.com/index.php?rid=561266&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16920478%26dopt%3DAbstract Authors: Lim MJ, Kern MJ While Coronary angiography remains the standard for the diagnosis and treatment of coronary artery disease within the cardiac catheterization lab, many lesion subsets require further investigation to determine their overall significance in causing symptoms. Direct measurement coronary flow and subsequently the ability to measure coronary pressure changes at maximal hyperemia have been developed to provide physiologic data to the catheterization operator which reveal the significance of coronary artery lesions in question and guide treatment. These measures, coronary flow reserve (CFR) and fractional flow reserve (FFR) have been validated against non-invasive tests for myocardial ischemia. Furthermore, FFR has also been studied in its ability to guide percutaneo... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561266 Tue, 01 Aug 2006 04:00:00 +0100 561266 http://www.medworm.com/index.php?rid=561267&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16824902%26dopt%3DAbstract Authors: Gau GT, Wright RS Atherosclerosis is a systemic diffuse disease that may manifest as an anglographically localized coronary, cerebral, mesenteric, renal, and/or peripheral arterial stenosis or as diffuse atherosclerosis. While relief of organ ischemia is frequently possible with percutaneous or surgical revascularization, this in itself does not alleviate the long-term risks of disease recurrence or modify the metabolic derangements that promote atherosclerosis. It is critically important to recognize the need for treatment of dyslipidemia and to institute necessary therapies. The complex role of lipoprotein abnormalities is well understood and the use of lipid-lowering agents (90% statins) is reviewed in both primary and secondary prevention. The clinical interaction with nov... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561267 Sat, 01 Jul 2006 04:00:00 +0100 561267 http://www.medworm.com/index.php?rid=561268&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16697902%26dopt%3DAbstract Authors: Walther T, Falk V, Mohr FW Heart valve surgery evolved since the early 1960s toward routine clinical application with good patient outcome. Different surgical techniques and valve prostheses have been developed. Thus standard procedures were continuously established. The different surgical procedures have now gained widespread clinical acceptance with good patient outcomes. Aortic valve stenosis and mitral valve incompetence are the most frequently acquired heart valve lesions in the western communities. Usually such lesions reach clinical significance in patients during their fifth to eighth decade of life. Standard surgical techniques of aortic valve repair and mitral valve replacement or repair result in persistent cure of the disease. Surgical access was gained using conve... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561268 Thu, 01 Jun 2006 04:00:00 +0100 561268 http://www.medworm.com/index.php?rid=561269&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16690376%26dopt%3DAbstract Authors: Riley MJ, Marrouche NF Due in large part to the growing dissatisfaction with traditional pharmacologic approaches to atrial fibrillation (AF) management, and fueled by both the fruits of basic and clinical investigation into the nature of AF initiation and maintenance and the explosive development in catheter-based technologies, AF ablation has matured from a purely investigational technique to a viable--and often preferred--strategy for treating patients suffering from this arrhythmia. Future insights and developments will help us refine our treatment strategies, making AF ablation safer, faster, and more effective. As the prevalence of AF in the general population continues to expand, the goal of optimizing our approach to AF becomes ever more important--and more pressing. ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561269 Mon, 01 May 2006 04:00:00 +0100 561269 http://www.medworm.com/index.php?rid=561270&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16546554%26dopt%3DAbstract Authors: Bashore TM, Cabell C, Fowler V With infective endocarditis afflicting 15,000 patients each year and with a mortality rate that still hovers at almost 40%, the disease remains a very serious health problem. Surprisingly, the incidence has not declined over the last 30 years, and now with more health care interventions, such as pacer/defibrillators, and an increasingly elderly population with degenerative valvular heart disease, the number susceptible to endocarditis is actually increasing. Given the weak evidence for endocarditis prophylaxis, there remains a large population at risk. Much has been learned recently about the pathogenesis of endocarditis, including the role of endothelial damage, platelet adhesion, and microbial adherence to the vegetation or intact valvular tiss... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561270 Sat, 01 Apr 2006 05:00:00 +0100 561270 http://www.medworm.com/index.php?rid=561271&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16503249%26dopt%3DAbstract Authors: Scarabelli TM, Knight R, Stephanou A, Townsend P, Chen-Scarabelli C, Lawrence K, Gottlieb R, Latchman D, Narula J Apoptosis, a genetically programmed form of cell death, contributes to myocyte cell loss in a variety of cardiac pathologies, including cardiac failure and those related to ischemia/reperfusion injury. The apoptotic program is complex, involving both pro- and anti-apoptotic proteins, and apoptosis occurs when the equilibrium between these opposing factors is perturbed. Some of these factors are intrinsic to the apoptotic pathway, such as the pro- and anti-apoptotic members of the Bcl2 family. Other, extrinsic, cellular factors can also modify the outcome of the response to an apoptotic stimulus. In this review, we have focused on some of these extrinsic factors, su... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561271 Wed, 01 Mar 2006 05:00:00 +0100 561271 http://www.medworm.com/index.php?rid=561273&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16413381%26dopt%3DAbstract Authors: Bucciarelli-Ducci C, Wu E, Lee DC, Holly TA, Klocke FJ, Bonow RO PMID: 16413381 [PubMed - indexed for MEDLINE] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561273 Wed, 01 Feb 2006 05:00:00 +0100 561273 http://www.medworm.com/index.php?rid=561275&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16389102%26dopt%3DAbstract Authors: Salam AM, Al Suwaidi J, Holmes DR The introduction and widespread use of coronary stents have been the most important advancement in the percutaneous treatment of coronary artery disease since the introduction of balloon angioplasty. Coronary artery stents reduce the rate of angiographic and clinical restenosis compared to balloon angioplasty. This angiographic restenosis was further reduced with the introduction of drug-eluting stents and hence further reduction in the frequency of major adverse cardiac events. Herein we present a comprehensive and up-to-date review about the use of drug-eluting stents in the treatment of coronary artery disease. PMID: 16389102 [PubMed - indexed for MEDLINE] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561275 Sun, 01 Jan 2006 05:00:00 +0100 561275 http://www.medworm.com/index.php?rid=561277&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16301095%26dopt%3DAbstract Authors: Wolk R, Gami AS, Garcia-Touchard A, Somers VK Sleep is an important modulator of cardiovascular function, both in physiological conditions and in disease states. In individuals without a primary sleep disorder, sleep may exert significant effects on the autonomic nervous system, systemic hemodynamics, cardiac function, endothelial function, and coagulation. Some of these influences can be directly linked to specific modulatory effects of sleep stages per se; others result from the natural circadian rhythm of various physiological processes. There is a temporal association between physiological sleep and occurrence of vascular events, cardiac arrhythmias, and sudden death. Epidemiological and pathophysiological studies also indicate that there may be a causal link between prima... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561277 Thu, 01 Dec 2005 05:00:00 +0100 561277 http://www.medworm.com/index.php?rid=561279&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16230183%26dopt%3DAbstract Authors: Barsness GW, Holmes DR, Gersh BJ Modern coronary revascularization strategies are based on studies performed in the 1970s and 1980s that compared coronary artery bypass surgery with standard medical therapy available at the time. Studies comparing surgical and percutaneous revascularization followed, demonstrating similar long-term outcome among thousands of randomized patients. The largest of these trials, the Bypass Angioplasty Revascularization Investigation (BARI), cast doubt on the generalizability of these findings to all subgroups, finding that patients with diabetes mellitus and multivessel disease had worse long-term outcome with an initial strategy of percutaneous transluminal coronary angioplasty (PTCA). Indeed, patients with diabetes mellitus are at increased risk ... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561279 Tue, 01 Nov 2005 05:00:00 +0100 561279 http://www.medworm.com/index.php?rid=561281&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16182016%26dopt%3DAbstract Authors: Roberts-Thomson KC, Kistler PM, Kalman JM Atrial tachycardia is an uncommon arrhythmia and may be focal or macroreentrant. This review concentrates on focal atrial tachycardia. Over the last decade there have been a number of advances in delineating the mechanism and anatomic locations of focal atrial tachycardia. The lack of efficacy of antiarrhythmic therapy and the advent of radiofrequency ablation have altered our primary approach to the treatment of focal atrial tachycardia. This review discusses the clinical features, diagnosis, and treatment of focal atrial tachycardia. There is particular focus on the mechanisms, anatomic locations, and P wave morphology, as well as the techniques of mapping and radiofrequency ablation. PMID: 16182016 [PubMed - indexed for MEDLINE]... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561281 Sat, 01 Oct 2005 04:00:00 +0100 561281 http://www.medworm.com/index.php?rid=561283&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16129122%26dopt%3DAbstract Authors: Braverman AC, Güven H, Beardslee MA, Makan M, Kates AM, Moon MR The bicuspid aortic valve affects 1 to 2% of the population and may be complicated by aortic stenosis or aortic insufficiency and infective endocarditis. The bicuspid aortic valve is associated with abnormalities of the aortic wall such as coarctation of the aorta, aortic dissection, and aortic aneurysm. Most patients with a bicuspid aortic valve will develop some complication during life. Individuals with a bicuspid valve may be unaware of its presence and are at risk for unsuspected complications. Aortic wall abnormalities associated with bicuspid aortic valve are due to cystic medial necrosis. This process is associated with increased metalloproteinase activity and apoptosis of vascular smooth muscle cells. Th... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561283 Thu, 01 Sep 2005 04:00:00 +0100 561283 http://www.medworm.com/index.php?rid=561285&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D16021110%26dopt%3DAbstract Authors: Frishman WH, Grattan JG, Mamtani R PMID: 16021110 [PubMed - indexed for MEDLINE] (Source: Current Problems in Cardiology) Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561285 Mon, 01 Aug 2005 04:00:00 +0100 561285 http://www.medworm.com/index.php?rid=561289&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D15973291%26dopt%3DAbstract Authors: Jefferson BK, Topol EJ Despite an increased knowledge of risk factors for atherosclerotic heart disease, it remains nearly endemic in Western society. Despite the high penetrance, only a fraction of those with the disease progress to develop a frank myocardial infarction (MI). Over the past decade, it has become clear that inflammation plays an important role in the pathogenesis of MI. Inflammatory arterial disease therefore may be a better term for the subset of patients that develop the serious adverse consequences related to the rupture of the intracoronary plaque. Using newer molecular techniques such as high-throughput SNP analysis, genome-wide scanning, and enriched pedigree analysis, many of the specific mechanisms underlying the inflammatory milieu involved in this tra... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561289 Fri, 01 Jul 2005 04:00:00 +0100 561289 http://www.medworm.com/index.php?rid=561291&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D15973249%26dopt%3DAbstract Authors: Mukherjee D, Eagle KA Acute aortic dissection is a medical emergency with high morbidity and mortality requiring emergent diagnosis and therapy. Rapid advances in noninvasive imaging technology have facilitated the early diagnosis of this condition and should be considered in the differential diagnosis of any patient with chest, back, or abdominal pain. Emergent surgery is the treatment for patients with type A dissection while optimal medical therapy is appropriate in patients with uncomplicated type B dissection. Adequate beta-blockade is the cornerstone of medical therapy. Patients who survive acute aortic dissection need long-term medical therapy with beta-blockers and statins and appropriate serial imaging follow-up. Future advances in this field include biomarkers in the... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561291 Wed, 01 Jun 2005 04:00:00 +0100 561291 http://www.medworm.com/index.php?rid=561293&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D15829899%26dopt%3DAbstract Authors: Rosenson RS When risk factors such as dyslipidemia and hypertension are inadequately controlled in subjects with the metabolic syndrome by lifestyle interventions, pharmacologic approaches are warranted. Statins are first-line pharmacotherapy for dyslipidemia due to their efficacy for lowering low-density lipoprotein (LDL) cholesterol and may also improve high-density lipoprotein (HDL) cholesterol and triglyceride levels. Fibrates and niacin may be useful in combination with a statin for additionally lowering triglycerides or raising HDL cholesterol. Adequate control of hypertension will usually require two or more drugs; agents that block the renin-angiotensin system are particularly useful in this population, given their demonstrated benefits for reducing the burden of cardi... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561293 Sun, 01 May 2005 04:00:00 +0100 561293 http://www.medworm.com/index.php?rid=561294&cid=s_35500_7_f&fid=35500&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D15778690%26dopt%3DAbstract Authors: Hersi A, Wyse DG Atrial fibrillation (AF) is the most common arrhythmia encountered in clinical practice. It is common in the elderly and those with structural heart disease. Clinical classification can be helpful in treatment decisions and the most widely accepted classification scheme (first episode, recurrent paroxysmal, recurrent persistent, permanent) is found in the ACC/AHA/ESC guidelines. The pathophysiology of AF remains unclear at this time. It is unlikely that a single pathophysiology is operative in all or even a majority of cases. Therapies to be considered for AF include prevention of thromboembolism, rate control, and restoration and maintenance of sinus rhythm. These therapies and specific treatments for these purposes are discussed under these headings, includi... Current Problems in Cardiology journals http://www.medworm.com/rss/comments.php?id=561294 Fri, 01 Apr 2005 05:00:00 +0100 561294