MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'CytoJournal' source. Thu, 09 Feb 2012 00:42:10 +0100 http://www.medworm.com/index.php?rid=5651020&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2012%3Bvolume%3D9%3Bissue%3D1%3Bspage%3D1%3Bepage%3D1%3Baulast%3DShidham Vinod B Shidham, Martha B Pitman, Richard M DeMayCytoJournal 2012 9(1):1-1Most of the scientific work presented as abstracts (platforms and posters) at various conferences have the potential to be published as articles in peer-reviewed journals. This DIY (Do It Yourself) article on how to achieve that goal is an extension of the symposium presented at the 36 th European Congress of Cytology, Istanbul, Turkey (presentation available on net at http://alturl.com/q6bfp). The criteria for manuscript authorship should be based on the ICMJE (International Committee of Medical Journal Editors) Uniform Requirements for Manuscripts. The next step is to choose the appropriate journal to submit the manuscript and review the 'Instructions to the authors' for that journal. Although initial... CytoJournal journals http://www.medworm.com/rss/comments.php?id=5651020 Tue, 31 Jan 2012 05:00:00 +0100 5651020 http://www.medworm.com/index.php?rid=5651019&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2012%3Bvolume%3D9%3Bissue%3D1%3Bspage%3D2%3Bepage%3D2%3Baulast%3DMonaco Sara E Monaco, Liron Pantanowitz, Walid E KhalbussCytoJournal 2012 9(1):2-2 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5651019 Tue, 31 Jan 2012 05:00:00 +0100 5651019 http://www.medworm.com/index.php?rid=5651018&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2012%3Bvolume%3D9%3Bissue%3D1%3Bspage%3D3%3Bepage%3D3%3Baulast%3DGriffin Adrienne Carruth Griffin, Lauren Ende Schwartz, Zubair BalochCytoJournal 2012 9(1):3-3 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5651018 Tue, 31 Jan 2012 05:00:00 +0100 5651018 http://www.medworm.com/index.php?rid=5651017&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2012%3Bvolume%3D9%3Bissue%3D1%3Bspage%3D4%3Bepage%3D4%3Baulast%3DBansal Conclusion : This prospective study shows that FNA smears from peripheral portion of the lesion are representative of the corresponding histopathological sections and it is possible to score and grade by SBR system on FNA smears. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5651017 Tue, 31 Jan 2012 05:00:00 +0100 5651017 http://www.medworm.com/index.php?rid=5546074&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D22%3Bepage%3D22%3Baulast%3DPurgina Bibianna Purgina, Ronald Jaffe, Sara E Monaco, Walid E Khalbuss, H Scott Beasley, John A Dunn, Liron PantanowitzCytoJournal 2011 8(1):22-22Erdheim-Chester disease (ECD) is a rare, multisystem disorder of macrophages. Patients manifest with histiocytic infiltrates that lead to xanthogranulomatous lesions in multiple organ systems. The cytologic features of this disorder are not well characterized. As a result, the cytologic diagnosis of ECD can be very challenging. The aim of this report is to describe the cytomorphology of ECD in a patient presenting with a retroperitoneal soft tissue lesion. A 54-year-old woman with proptosis and diabetes insipidus was found on imaging studies to have multiple intracranial lesions, sclerosis of both femurs and a retroperitoneal soft tissue mass. Fine need... CytoJournal journals http://www.medworm.com/rss/comments.php?id=5546074 Tue, 27 Dec 2011 05:00:00 +0100 5546074 http://www.medworm.com/index.php?rid=5546073&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D23%3Bepage%3D23%3Baulast%3DShidham Vinod B Shidham, Richard M DeMay, Martha B PitmanCytoJournal 2011 8(1):23-23CytoJournal, with its continued contribution of scientific cytopathology literature to the public domain under open access (OA) charter, thanks its dedicated peer reviewers for devoting significant efforts, time, and resources during 2011. The abstracts of poster-platform submissions to the 59 th Annual Scientific Meeting (November 2011) of the American Society of Cytopathology (ASC) in Baltimore, MD, USA, were peer reviewed by the ASC Scientific Program Committee. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5546073 Tue, 27 Dec 2011 05:00:00 +0100 5546073 http://www.medworm.com/index.php?rid=5546072&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D24%3Bepage%3D24%3Baulast%3DYildiz%252DAktas Conclusions: TP of the testis is a helpful adjunct to biopsy because of its ability to clearly evaluate all stages of spermatogenesis. These data demonstrate that TP cytopathology of the testes in our experience has an excellent correlation with both normal testicular biopsies and those showing pathological spermatogenesis, and in rare cases may provide added benefit in evaluating the presence of spermatogenesis for male infertility. Albeit uncommon, cytopathologists may be required to identify and evaluate spermatogenic elements in cytology specimens being submitted from men with infertility. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5546072 Tue, 27 Dec 2011 05:00:00 +0100 5546072 http://www.medworm.com/index.php?rid=5433468&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D20%3Bepage%3D20%3Baulast%3DGriffin Conclusions : The data demonstrate no remarkable difference in diagnostic yield, the number of sites sampled per patient, or clinical decision making between specimens collected via EBUS-TBNA with or without ROSE. As a result, this study challenges the notion that ROSE is beneficial for the evaluation of EBUS-TBNA specimens. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5433468 Mon, 21 Nov 2011 05:00:00 +0100 5433468 http://www.medworm.com/index.php?rid=5433467&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D21%3Bepage%3D21%3Baulast%3DOno Conclusions: Cytology is a better predictor of malignancy than symptoms, for the conservative management of small branch-duct IPMNs. Cytology contributes to a highly accurate triple negative test for malignancy in small IPMN: No dilated MPD, MN or HGA. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5433467 Mon, 21 Nov 2011 05:00:00 +0100 5433467 http://www.medworm.com/index.php?rid=5366914&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D19%3Bepage%3D19%3Baulast%3DPaksoy Conclusions: Nondominant nodules could harbor malignancy. The risk of malignancy in nondominant nodules in MNG should not be underestimated. We have shown that the dominant nodule in patients with MNG was in fact about 2.5 times more likely to be malignant than a nondominant nodule. The use of FNAC for nondominant nodules could enhance the likelihood of detecting malignancy in an MNG. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5366914 Mon, 31 Oct 2011 04:00:00 +0100 5366914 http://www.medworm.com/index.php?rid=5366915&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D18%3Bepage%3D18%3Baulast%3DKhalbuss Conclusions: The most common cytomorphologic patterns seen in body cavity effusions of SCC and LCNEC were small-cell clusters with nuclear molding. However, in 51% of the cases either a predominant single-cell pattern mimicking lymphoma or large-cell clusters mimicking non-small carcinoma were noted. In our experience, effusions were the first manifestation of disease in the majority of patients diagnosed with neuroendocrine carcinoma. Therefore, familiarity with the cytomorphological spectrum of neuroendocrine carcinomas in fluid cytology may help in rapidly establishing an accurate diagnosis and in directing appropriate management. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5366915 Sat, 29 Oct 2011 04:00:00 +0100 5366915 http://www.medworm.com/index.php?rid=5263356&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D17%3Bepage%3D17%3Baulast%3DChitragar We present the case of a 25-year-old patient with extramedullary involvement of lymph node and cerebrospinal fluid by AML M7, describing in detail, the morphological features on aspiration as well as exfoliative cytology. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5263356 Tue, 27 Sep 2011 04:00:00 +0100 5263356 http://www.medworm.com/index.php?rid=5228657&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D16%3Bepage%3D16%3Baulast%3D CytoJournal 2011 8(1):16-16These are peer-reviewed poster-platform submissions finalized by the Scientific Program Committee. A total of 153 abstracts (14 Platforms [PP1 through PP14] & 139 Posters [1 through 139]) were selected from 161 submissions to be considered for presentation during November 4 - 8, 2011, at the Hilton Baltimore Hotel, to pathologists, cytopathologists, cytotechnologists, residents, fellows, students, and other members of cytopathology-related medical and scientific fields. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5228657 Fri, 16 Sep 2011 04:00:00 +0100 5228657 http://www.medworm.com/index.php?rid=5149060&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D15%3Bepage%3D15%3Baulast%3DArya We report, for the first time, striking neutrophil-tumor cell cannibalism associated with a high grade, aggressive and metastatic salivary duct carcinoma of the parotid gland highlighted within cytological and surgical excision pathology specimens. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5149060 Tue, 23 Aug 2011 23:00:00 +0100 5149060 http://www.medworm.com/index.php?rid=5149061&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D14%3Bepage%3D14%3Baulast%3DArora Conclusions: A limited panel of two monoclonal antibodies, calretinin and Ber-EP4, may be useful in cytology, as a "primary antibody panel", for accurate diagnosis and patient management. Additionally, ICC can be performed easily on cytospin preparations, which gave results comparable to cell blocks in our study. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5149061 Wed, 27 Jul 2011 23:00:00 +0100 5149061 http://www.medworm.com/index.php?rid=5149062&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D13%3Bepage%3D13%3Baulast%3DCakir Conclusions: Despite that adenocarcinoma is the most common cause of malignant pleural effusions, there is a significant number of hematological and non-hematological uncommon causes of such effusions. Cytopathologists and clinicians must keep in mind these uncommon entities in routine practice for an accurate diagnosis. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=5149062 Mon, 18 Jul 2011 23:00:00 +0100 5149062 http://www.medworm.com/index.php?rid=4963461&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D11%3Bepage%3D11%3Baulast%3DDevata Conclusion: In addition to poor inter-observer reproducibility, CRPM alone in cases with scant amyloid led to frequent false negative results (9 out of 9, 100%). For improved detection of AL, routine ultrastructural evaluation with EM of fat pad aspirates by evaluating at least 15 small blood vessels in the aspirated fibroadipose tissue is recommended. Given the high false negative rate for CRPM alone in early disease, routine reflex evaluation with EM is highly recommended to avert the invasive option of biopsying various organs in cases with high clinical suspicion for AL. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4963461 Wed, 22 Jun 2011 23:00:00 +0100 4963461 http://www.medworm.com/index.php?rid=4963460&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D12%3Bepage%3D12%3Baulast%3DMalami Conclusions: The utilization of FNA is apparently lagging in Nigeria. Given its potential in resource-constrained settings, we are of the opinion that it should be used more often in clinical and translational research. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4963460 Wed, 22 Jun 2011 23:00:00 +0100 4963460 http://www.medworm.com/index.php?rid=4925470&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D10%3Bepage%3D10%3Baulast%3DKhazai Conclusions: EBUS-TBNA biopsy is a sensitive and specific method for evaluating mediastinal lymphadenopathy in patients with lung and other primary tumors. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4925470 Mon, 30 May 2011 23:00:00 +0100 4925470 http://www.medworm.com/index.php?rid=4879641&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D9%3Bepage%3D9%3Baulast%3DZhang Conclusion: We conclude that cytology screening of high risk teenagers is effective in detecting CIN 2/3 lesions. Moreover, treatment and careful follow-up can be realized. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4879641 Mon, 30 May 2011 23:00:00 +0100 4879641 http://www.medworm.com/index.php?rid=4795854&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D8%3Bepage%3D8%3Baulast%3DBanik Conclusions: A raised prevalence of epithelial cell abnormality reflects the lack of awareness about cervical cancer screening. Women aged 45 or above harbor the bulk of premalignant and malignant lesions in the Pap smear, signifying that these women are among the under users of cytological screening. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4795854 Fri, 06 May 2011 23:00:00 +0100 4795854 http://www.medworm.com/index.php?rid=4737840&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D7%3Bepage%3D7%3Baulast%3DGilbert Conclusions: Our data shows that although metastases to the pancreas are rare, they can present as a solitary mass many years after the primary malignancy is diagnosed and can even be the first manifestation of an extrapancreatic primary in a small number of cases. It is important to consider the possibility of a metastatic lesion in the pancreas because this may require a different management than a primary pancreatic tumor. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4737840 Wed, 20 Apr 2011 23:00:00 +0100 4737840 http://www.medworm.com/index.php?rid=4542106&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D5%3Bepage%3D5%3Baulast%3DSirikanjanapong We report cytologic features of MAC and also suggest that MAC can possibly be diagnosed by FNA with the appropriate clinical vignette and immunohistochemical profile.. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542106 Thu, 03 Mar 2011 00:00:00 +0100 4542106 http://www.medworm.com/index.php?rid=4542105&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D6%3Bepage%3D6%3Baulast%3DLang In conclusion, although STBP is a rare neoplasm, these cases may be encountered in respiratory cytology samples. FNA of papillomas yields fewer lesional cells compared to exfoliative samples. These lesions may be mistaken in cytology specimens for squamous cell carcinoma, squamous-lined cavitary lesions, an infectious (fungal) process, reactive squamous metaplasia, or oral contamination. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542105 Thu, 03 Mar 2011 00:00:00 +0100 4542105 http://www.medworm.com/index.php?rid=4542108&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D3%3Bepage%3D3%3Baulast%3DShi Yuquan Shi, Adrienne Carruth Griffin, Paul JL Zhang, James N Palmer, Prabodh GuptaCytoJournal 2011 8(1):3-3Rosai-Dorfman disease (RDD), a rare, benign, self-limiting histiocytic proliferative disorder, can be encountered in both nodal and extranodal locations, and fine needle aspiration (FNA), a simple, accurate and economic tool, has been widely used for the diagnosis of superficial and deep-seated lesions. Familiarity with the cytomorphologic features of RDD is important as prognosis and treatment are quite different from other benign or malignant diseases for which it may clinically masquerade. Although large numbers of RDD cases have been reported, review of the literature has revealed 49 reported cases of RDD diagnosed by FNA. Here, we report a case of RDD with nasal and sinus involve... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542108 Sat, 12 Feb 2011 00:00:00 +0100 4542108 http://www.medworm.com/index.php?rid=4542107&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D4%3Bepage%3D4%3Baulast%3DRekhi Bharat Rekhi, SV KaneCytoJournal 2011 8(1):4-4 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542107 Sat, 12 Feb 2011 00:00:00 +0100 4542107 http://www.medworm.com/index.php?rid=4542110&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D1%3Bepage%3D1%3Baulast%3DShidham Conclusion: p16 immunostaining on cell block sections of cervical cytology specimens showed distinct correlation patterns with biopsy results. Reflex p16 immunostaining of cell blocks based on the algorithmic approach to be evaluated by a multiinstitutional comprehensive prospective study is proposed. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542110 Mon, 31 Jan 2011 00:00:00 +0100 4542110 http://www.medworm.com/index.php?rid=4542109&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2011%3Bvolume%3D8%3Bissue%3D1%3Bspage%3D2%3Bepage%3D2%3Baulast%3DCrowe We present here a unique case of metastatic FL-HCC diagnosed by endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) of mediastinal adenopathy. A 32-year-old woman with a history of oral contraceptive use presented with nausea and severe abdominal pain but no ascites or stigmata of cirrhosis. She had a past history of resection of a liver lesion. Serial computed tomography scans revealed mediastinal lymphadenopathy and the patient was referred for endoscopic ultrasound (EUS). A transesophageal EUS-FNA was performed and tissue was collected for cytological evaluation by an on-site pathologist with no knowledge of prior history. Based on morphology correlated with prior history received later, a final diagnosis of metastatic FL-HCC in the retrocardiac lymph node was rendered on the ... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542109 Mon, 31 Jan 2011 00:00:00 +0100 4542109 http://www.medworm.com/index.php?rid=4542113&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D24%3Bepage%3D24%3Baulast%3DSauer Conclusions : Liquid suspensions and liquid based slide preparations seem to offer an optimal pre-fixation and preservation of ER/PgR in breast carcinoma cells. Post-fixation with 4% formalin followed by microwave-stimulated epitope retrieval before immunostaining is recommended. Long-time storage of liquid based specimens at -20°C or -74°C for at least 6 months without significant loss of immunoreactivity is feasible. They may be used as internal positive and negative controls. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542113 Fri, 31 Dec 2010 00:00:00 +0100 4542113 http://www.medworm.com/index.php?rid=4542112&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D25%3Bepage%3D25%3Baulast%3DSetia Conclusion: Primary cervicovaginal melanoma, a rare malignancy seen predominantly in postmenopausal women, may be successfully diagnosed in either ThinPrep Pap tests or conventional Pap smears. While ThinPrep Pap tests did not demonstrate morphological advantage over conventional smears, liquid-based cytology specimens did provide additional material for cellblock preparation and immunocytochemical evaluation in a subset of cases. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542112 Fri, 31 Dec 2010 00:00:00 +0100 4542112 http://www.medworm.com/index.php?rid=4542111&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D26%3Bepage%3D26%3Baulast%3DShidham Vinod B ShidhamCytoJournal 2010 7(1):26-26 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542111 Fri, 31 Dec 2010 00:00:00 +0100 4542111 http://www.medworm.com/index.php?rid=4542115&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D22%3Bepage%3D22%3Baulast%3DAl%252DAbbadi Mousa A Al-Abbadi, Leonard I Bloom, Lisa A Fatheree, Lori A Haack, Gerald Minkowitz, David C Wilbur, Marshall R AustinCytoJournal 2010 7(1):22-22 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542115 Mon, 18 Oct 2010 00:00:00 +0100 4542115 http://www.medworm.com/index.php?rid=4542114&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D23%3Bepage%3D23%3Baulast%3DDhillon Inderpreet Dhillon, Martha B Pitman, Richard M DeMay, Pamela Archuletta, Vinod B ShidhamCytoJournal 2010 7(1):23-23The confusion centered around appropriate use of the CPT billing code 88172 is addressed in the commentary from the Economic and Government Affairs Committee of the American Society of Cytopathology (ASC) who have written a timely commentary in this issue of Cytojournal, "Adequate Reimbursement is Crucial to Support Cost-Effective Rapid Onsite Cytopathology Evaluations". Currently, lack of standardized use within and between pathology departments is stirring unhealthy practices of denying reimbursements for this critical and legitimate cytopathology service. This editorial discusses the important concerns raised in this commentary and recommends immediate corrective ... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542114 Mon, 18 Oct 2010 00:00:00 +0100 4542114 http://www.medworm.com/index.php?rid=4054530&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D20%3Bepage%3D20%3Baulast%3DKastenbaum Conclusion: In our review of SLL/CLL, coincident entities were present in 31% of the cases and included a spectrum of non-neoplastic and neoplastic processes. FC was the most frequently utilized ancillary test, but IHC provided important information by excluding a mantle cell lymphoma or confirming a coincident process. Thus, cytomorphologic evaluation in these patients is important due to the high risk of a coincident process that may not be apparent by FC alone and may require clinical management. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4054530 Sun, 10 Oct 2010 23:00:00 +0100 4054530 http://www.medworm.com/index.php?rid=4054529&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D21%3Bepage%3D21%3Baulast%3DBeraki Elsa Beraki, Torill SauerCytoJournal 2010 7(1):21-21During the last years, HER-2 status kits and protocols for chromogen visualization of hybridization signals have come on the market. The first generation using chromogen visualization used single color probes. The second generation, now emerging on the market, uses dual chromogen visualization. The aim of this study has been to test a new dual color chromogen kit (Ventana INFORM HER2 Dual Colour ISH Roche ® ) and compare the results with our in-house method(s). The material consisted primarily of cytological material from invasive breast carcinomas in 49 women. Dual SISH was done on all 49 cytological and histological specimens. The histological specimens were treated according to the manufacturer's recommendations. The proc... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4054529 Sun, 10 Oct 2010 23:00:00 +0100 4054529 http://www.medworm.com/index.php?rid=4542116&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D18%3Bepage%3D18%3Baulast%3DPurohit Chetna N Purohit, Marilyn M Bui, Ardeshir HakamCytoJournal 2010 7(1):18-18Osteoclast-rich undifferentiated carcinoma of urinary bladder (ORUCUB) is a very rare and an unusual variant of high-grade urothelial carcinoma. Here, we report an extraordinary case of metastatic ORUCUB, diagnosed by fine needle aspiration (FNA) biopsy, in a 74-year-old Hispanic male who presented with a palpable, tender left groin mass and a known previous history of high-grade carcinoma of urinary bladder and prostatic cancer. To the best of our knowledge, diagnosis of ORUCUB by FNA is the first case report in FNA cytology to be published to date. A review of the literature is emphasized on the cytological, histological and immunohistochemical features and differential diagnoses of giant cell tumor. (Source: CytoJ... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542116 Fri, 17 Sep 2010 00:00:00 +0100 4542116 http://www.medworm.com/index.php?rid=4029155&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D17%3Bepage%3D17%3Baulast%3DGahine Renuka Gahine, Vijaya Sudarshan, Nighat Hussain, Chandani KrishnaniCytoJournal 2010 7(1):17-17Fine needle aspiration cytology (FNAC) is commonly being used with increasing frequency for the pre-operative evaluation of salivary gland lesions. However, it has areas of considerable interpretational difficulties. The most frequent problems involve variations in the expected cytology of pleomorphic adenoma (PA). Salivary gland FNACs performed at Pt. JNM Medical College, Raipur, Chhattisgarh, during July 2006 to June 2007 were reviewed, and we report four cases of interesting diagnostic dilemma. As PA is the most common salivary gland neoplasm, it should always be considered and ruled out as the first differential in the diagnosis of salivary gland FNACs. In order to avoid diagnostic pitfalls, w... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029155 Thu, 16 Sep 2010 23:00:00 +0100 4029155 http://www.medworm.com/index.php?rid=4029151&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D18%3Bepage%3D18%3Baulast%3DBui Marilyn M Bui, Chetna N Purohit, Ardeshir HakamCytoJournal 2010 7(1):18-18Osteoclast-rich undifferentiated carcinoma of urinary bladder (ORUCUB) is a very rare and an unusual variant of high-grade urothelial carcinoma. Here, we report an extraordinary case of metastatic ORUCUB, diagnosed by fine needle aspiration (FNA) biopsy, in a 74-year-old Hispanic male who presented with a palpable, tender left groin mass and a known previous history of high-grade carcinoma of urinary bladder and prostatic cancer. To the best of our knowledge, diagnosis of ORUCUB by FNA is the first case report in FNA cytology to be published to date. A review of the literature is emphasized on the cytological, histological and immunohistochemical features and differential diagnoses of giant cell tumor. (Source: CytoJ... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029151 Thu, 16 Sep 2010 23:00:00 +0100 4029151 http://www.medworm.com/index.php?rid=4029147&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D19%3Bepage%3D19%3Baulast%3DSetia Conclusion: Eosinophilic gastroenteritis with subserosal involvement should be added to the list of causes for eosinophils in peritoneal fluid. The finding of eosinophilic ascites, with appropriate clinical and laboratory findings, may warrant the need to perform laparoscopic intestinal biopsies to confirm the diagnosis. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029147 Thu, 16 Sep 2010 23:00:00 +0100 4029147 http://www.medworm.com/index.php?rid=4063226&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D13%3Bepage%3D13%3Baulast%3DSiderits We report a case of a 59-year-old male with ring-enhancing brain lesions, bilateral adrenal masses, lung and vocal cord nodules, where the diagnosis of exclusion was metastatic malignancy. Fine needle aspiration (FNA) of the adrenal mass and a subsequent vocal cord biopsy confirmed chronic widely disseminated blastomycosis. Flow cytometric evaluation of peripheral blood documented persistent selective CD4+ lymphocytopenia with T8 (suppressor) T-Lymphocyte count within normal range. We believe that idiopathic CD4+ lymphocytopenia is an important etiologic factor to be considered for patients who present with mass lesions and are diagnosed by FNA with atypical fungal infections. We relate the diagnostic criteria for idiopathic CD4+ lymphocytopenia and the importance of p... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063226 Wed, 04 Aug 2010 23:00:00 +0100 4063226 http://www.medworm.com/index.php?rid=4029167&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D14%3Bepage%3D14%3Baulast%3DYakoushina Tatiana V Yakoushina, Ehud Lavi, RS HodaCytoJournal 2010 7(1):14-14Pituitary carcinoma (PC) is a very rare entity (0.2% of all pituitary tumors), with only about 140 cases reported in English literature. There are no reliable histological, immunohistochemical or ultrastructural features distinguishing pituitary adenoma (PA) from PC. By definition, a diagnosis of PC is made after a patient with PA develops non-contiguous central nervous system (CNS) or systemic metastases. To date, only three cases of PC have been reportedly diagnosed on fine needle aspiration (FNA). Two of the reported cases were diagnosed on FNA of the cervical lymph nodes and one on FNA of the vertebral bone lesion. Herein, we present a case of PC, diagnosed on FNA of the liver lesion. In this case, we describe cy... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029167 Wed, 04 Aug 2010 23:00:00 +0100 4029167 http://www.medworm.com/index.php?rid=4029163&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D15%3Bepage%3D15%3Baulast%3DRekhi Conclusions: Critical review is helpful in further reducing the number of ASC cases. The percentage of cases with CIN 2 and above is higher with ASC-H cases. The reason for relative increase in HSILs in the present study included referral bias in the screening program. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029163 Wed, 04 Aug 2010 23:00:00 +0100 4029163 http://www.medworm.com/index.php?rid=4029159&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D16%3Bepage%3D16%3Baulast%3DDasari Conclusions: Patients with persistent inflammatory Pap smears can harbour a high proportion of CIN and hence these patients will need further evaluation. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029159 Wed, 04 Aug 2010 23:00:00 +0100 4029159 http://www.medworm.com/index.php?rid=4063241&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D10%3Bepage%3D10%3Baulast%3DSauer Conclusions: Metastases from extra mammary sites are (relatively) common in males (23.3%). In women, metastatic lesions are rare (0.46%). A large proportion of them (88%) are high-grade adenocarcinomas and poorly differentiated carcinomas that may resemble grade 3 ductal carcinomas. Unusual clinical and/or radiological presentation in combination with high-grade malignant cells should alert us to consider the possibility of a metastasis. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063241 Thu, 01 Jul 2010 23:00:00 +0100 4063241 http://www.medworm.com/index.php?rid=4063236&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D11%3Bepage%3D11%3Baulast%3DKhader Conclusions: Our results show that AC2 assay of 1.5 ml SP samples transferred to APTIMA specimen transfer medium within seven days is sufficiently sensitive and specific to be used to screen for CT and GC. CT sensitivity may be somewhat reduced in samples from patients over 25 years. SP specimens retained in the original SP fixative for longer time intervals also may have decreased sensitivity, due to deterioration of RNA, but this was not assessed in this study. The ability to tap the live pathology database is a valuable tool that can useful to conduct clinical studies without a costly prospective clinical trial. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063236 Thu, 01 Jul 2010 23:00:00 +0100 4063236 http://www.medworm.com/index.php?rid=4063231&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D12%3Bepage%3D12%3Baulast%3DLi We report a case of RDD diagnosed by FNA cytology in a 28 year-old female presented as an osteolytic lesion of superior pubic ramus where the differential diagnosis included a sarcoma and lymphoma. Based on the cytologic findings, a diagnosis of a RDD was considered during the rapid FNA on site with no clinical history provided. The diagnosis of RDD was further confirmed by immunohistochemical stains and histology diagnosis. Our findings show that even in the absence of a clinical history, FNA is a less invasive and a very reliable tool for the diagnosis of SHML (RDD). (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063231 Thu, 01 Jul 2010 23:00:00 +0100 4063231 http://www.medworm.com/index.php?rid=4063245&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D9%3Bepage%3D9%3Baulast%3DMonaco Conclusions: This study illustrates the cytomorphology of five EBUS FNA cases that address some of the diagnostic challenges witnessed while examining these specimens during ROSE. Many of the difficulties faced can be attributed to the baseline cellularity of the aspirates, the bronchial contamination, the difficulty identifying neoplasms with bland cytology, the wide spectrum of diseases that can occur in the mediastinum with overlapping cytomorphologic features, the mismatch between the background material and the cell populations present, and the overall unfamiliarity with these types of specimens. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063245 Sun, 13 Jun 2010 23:00:00 +0100 4063245 http://www.medworm.com/index.php?rid=4063253&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D7%3Bepage%3D7%3Baulast%3DPantanowitz Liron Pantanowitz, Michael Kuperman, Robert A GoulartCytoJournal 2010 7(1):7-7Human immunodeficiency virus (HIV)-infected patients are at an increased risk for developing opportunistic infections, reactive conditions and neoplasms. As a result, a broad range of conditions are frequently included in the differential diagnosis of HIV-related lesions. The clinical history of HIV infection may, however, be misleading in some cases. Illustrative cases are presented in which knowledge of a patient's HIV status proved to be misleading and increased the degree of complexity of the cytologic evaluation. Case 1 involved the fine needle aspiration (FNA) of a painful 3 cm unilateral neck mass in a 38-year-old female with generalized lymphadenopathy. Her aspirate revealed a spindle cell prolifer... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063253 Fri, 11 Jun 2010 23:00:00 +0100 4063253 http://www.medworm.com/index.php?rid=4063249&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D8%3Bepage%3D8%3Baulast%3DMichelow Conclusion: The current appropriate management of HIV-positive women in low-resource settings with a diagnosis of ASC-H on cervical smear is colposcopy, despite the costs involved. In the future and if cost-effective in developing nations, use of novel markers may help select which HIV-positive women can be managed conservatively and which ones referred for more active treatment. More research in this regard is warranted. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063249 Fri, 11 Jun 2010 23:00:00 +0100 4063249 http://www.medworm.com/index.php?rid=3631262&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D23%3Bepage%3D23%3Baulast%3DJeronimo Jeronimo Jose, Barone Mark A, Luciani Silvana, Lu Ricky, Sherris Jacqueline, Torod Julie, Tsu VivienCytoJournal 2009 6(1):23-23 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=3631262 Sat, 05 Jun 2010 13:55:13 +0100 3631262 http://www.medworm.com/index.php?rid=3631261&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D20%3Bepage%3D20%3Baulast%3DNgae Ngae Min Yi, Crowder Clinton D, Kjeldahl Klint, Gamez Roberto, Paulson Samantha, McKeon Daniel M, Goyal Priti, Pambuccian Stefan ECytoJournal 2009 6(1):20-20 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=3631261 Sat, 05 Jun 2010 13:55:13 +0100 3631261 http://www.medworm.com/index.php?rid=3631260&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D12%3Bepage%3D12%3Baulast%3DAustin Austin R Marshall, Zhao ChengquanCytoJournal 2009 6(1):12-12 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=3631260 Sat, 05 Jun 2010 13:55:13 +0100 3631260 http://www.medworm.com/index.php?rid=4063257&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D6%3Bepage%3D6%3Baulast%3DGupta Conclusion: With necessary investments and resources a point-of-care FNA service has been created which has improved patient care. This, albeit with certain modifications may serve as a model for FNA service. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063257 Tue, 11 May 2010 23:00:00 +0100 4063257 http://www.medworm.com/index.php?rid=4542117&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D5%3Bepage%3D5%3Baulast%3DAl%252DMaghraby We present a case of dedifferentiated liposarcoma diagnosed by fine-needle aspiration (FNA), using cytomorphology and ancillary studies (immunocytochemistry and fluorescent in-situ hybridization). An 85-year old female presented to our institution with a firm soft tissue mass of the right buttock. The FNA showed atypical spindle cells, osteoclast-like giant cells and extracellular dense matrix material. The cell block showed cellular groups of highly atypical spindle cells with osteoid and adipose tissue. Fluorescence in situ hybridization (FISH) studies performed on the cell block demonstrated amplification of the MDM2 gene. In addition, the findings were morphologically compatible with the previously resected retroperitoneal dedifferentiated liposarcoma with areas of osteosarcoma. This r... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542117 Tue, 06 Apr 2010 00:00:00 +0100 4542117 http://www.medworm.com/index.php?rid=4063272&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D3%3Bepage%3D3%3Baulast%3DDenice We describe the Duet imaging system, our experiences with implementation, and outline the financial investment, space requirements, information technology needs, validation, and training of cytotechnologists needed to integrate such a system into a cytology laboratory. Before purchasing the imaging system, we evaluated and validated the instrument at our facility. Implementation required slide preparation changes, IT modifications, development of training programs, and revision of job descriptions for cytotechnologists. A darkened room was built to house the automated scanning station and microscope, as well as two imaging stations. IT changes included generation of storage for archival images on the LAN, addition of external hard drives for back-up, and changes to cable connections for co... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063272 Mon, 05 Apr 2010 23:00:00 +0100 4063272 http://www.medworm.com/index.php?rid=4063267&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D4%3Bepage%3D4%3Baulast%3DGupta Ruchika Gupta, Sandeep R Mathur, Venkateswaran K Iyer, Sudheer A Kumar, Amlesh SethCytoJournal 2010 7(1):4-4Effusions, especially peritoneal, are seen in less than 2% of patients with renal cell carcinoma (RCC). Since the tumor cells in RCC are bland and nondescript, the involvement of serous effusions is difficult to diagnose. An accurate recognition of malignant effusion and differentiation from reactive mesothelial cells is imperative. A 55-year-old male presented with gradually progressive ascites. Cytospin preparations from ascitic fluid showed reactive mesothelial cells admixed with few smooth-contoured clusters of cells with moderate cytoplasm, vesicular nuclei with prominent nucleolus. He had undergone nephrectomy for papillary RCC two years earlier. Another 36-year-old man ... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063267 Mon, 05 Apr 2010 23:00:00 +0100 4063267 http://www.medworm.com/index.php?rid=4063262&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D5%3Bepage%3D5%3Baulast%3DAl-Maghraby We present a case of dedifferentiated liposarcoma diagnosed by fine-needle aspiration (FNA), using cytomorphology and ancillary studies (immunocytochemistry and fluorescent in-situ hybridization). An 85-year old female presented to our institution with a firm soft tissue mass of the right buttock. The FNA showed atypical spindle cells, osteoclast-like giant cells and extracellular dense matrix material. The cell block showed cellular groups of highly atypical spindle cells with osteoid and adipose tissue. Fluorescence in situ hybridization (FISH) studies performed on the cell block demonstrated amplification of the MDM2 gene. In addition, the findings were morphologically compatible with the previously resected retroperitoneal dedifferentiated liposarcoma with areas of osteosarcoma. This r... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063262 Mon, 05 Apr 2010 23:00:00 +0100 4063262 http://www.medworm.com/index.php?rid=4063277&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D2%3Bepage%3D2%3Baulast%3DRimiene Conclusions: PapSpin showed good qualitative results in both study arms, even after the material splitting in the first study arm, and is a good alternative to the conventional Pap smear. Additionally, the PapSpin method offers several advantages such as the opportunity to prepare duplicate slides, option for HPV DNA testing and cell block preparations from residual material. Microscopic evaluation of thinner cell preparations is less time consuming than the conventional Pap smears. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063277 Sat, 20 Mar 2010 00:00:00 +0100 4063277 http://www.medworm.com/index.php?rid=3345006&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D23%3Bepage%3D23%3Baulast%3DJeronimo Jeronimo Jose, Barone Mark A, Luciani Silvana, Lu Ricky, Sherris Jacqueline, Torod Julie, Tsu VivienCytoJournal 2009 6(1):23-23 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=3345006 Tue, 09 Mar 2010 15:26:04 +0100 3345006 http://www.medworm.com/index.php?rid=3345005&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D20%3Bepage%3D20%3Baulast%3DNgae Ngae Min Yi, Crowder Clinton D, Kjeldahl Klint, Gamez Roberto, Paulson Samantha, McKeon Daniel M, Goyal Priti, Pambuccian Stefan ECytoJournal 2009 6(1):20-20 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=3345005 Tue, 09 Mar 2010 15:26:04 +0100 3345005 http://www.medworm.com/index.php?rid=3345004&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D12%3Bepage%3D12%3Baulast%3DAustin Austin R Marshall, Zhao ChengquanCytoJournal 2009 6(1):12-12 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=3345004 Tue, 09 Mar 2010 15:26:04 +0100 3345004 http://www.medworm.com/index.php?rid=4063282&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2010%3Bvolume%3D7%3Bissue%3D1%3Bspage%3D1%3Bepage%3D1%3Baulast%3DShidham Vinod B Shidham, George Varsegi, Krista D'AmoreCytoJournal 2010 7(1):1-1Background: The evaluation of serous fluids by conventional one color immunocytochemistry is complex and challenging. Design: We selected and studied 37 serous fluid cytology specimens (23 pleural, 13 peritoneal, 1 pericardial), collected over a 4-year period. They were unequivocally positive for metastatic adenocarcinoma based on clinical correlation, cytomorphology, and one color immunocytochemistry on cell block sections. 3 µm serial sections of cell blocks were immunostained by a two chromogen method (peroxidase with brown chromogen followed by alkaline phosphatase with red chromogen). Combinations evaluated were: A- vimentin followed by cytokeratin (CK) 7; B- calretinin followed by BerEP4, C- ca... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063282 Wed, 10 Feb 2010 00:00:00 +0100 4063282 http://www.medworm.com/index.php?rid=3174064&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D25%3Bepage%3D25%3Baulast%3DGupta We describe a case of a young healthy adult male who was found to have multiple hepatic masses on radiologic investigations. A guided fine needle aspiration demonstrated a poorly differentiated neoplasm. The diagnosis was made on core biopsy assisted by immunohistochemistry, which showed characteristic features of EH. He is doing well 14 months after diagnosis, without surgical excision or chemotherapy. An accurate diagnosis of hepatic EH on aspiration cytology requires an adequate specimen and awareness of its cytologic features, including discohesive atypical cells with intracytoplasmic lumina and intranuclear inclusions. Since this tumor is usually unresectable but has a favorable prognosis as compared to hepatocellular carcinoma, a correct diagnosis is essential for appropriate managem... CytoJournal journals http://www.medworm.com/rss/comments.php?id=3174064 Fri, 15 Jan 2010 14:56:49 +0100 3174064 http://www.medworm.com/index.php?rid=3174063&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D24%3Bepage%3D24%3Baulast%3DHalloush Conclusion:</b> FPFNA for SA is not as good as previously reported. This may be due to different practice setting, level of experience, diagnostic technique, or absence of abdominal soft tissue involvement. A negative result of FPFNA does not exclude SA. Immune phenotyping of amyloid is possible on cell block. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=3174063 Fri, 15 Jan 2010 14:56:49 +0100 3174063 http://www.medworm.com/index.php?rid=2997879&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D23%3Bepage%3D23%3Baulast%3DJeronimo Jeronimo Jose, Barone Mark A, Luciani Silvana, Lu Ricky, Sherris Jacqueline, Torod Julie, Tsu VivienCytoJournal 2009, 6:23 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2997879 Tue, 17 Nov 2009 15:00:45 +0100 2997879 http://www.medworm.com/index.php?rid=2878045&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D22%3Bepage%3D22%3Baulast%3DDua Dua Kulwinder S, Vijayapal Aravind S, Kengis Janis, Shidham Vinod BCytoJournal 2009, 6:22A 51-year-old male presented with a 4-month history of abdominal pain, decreased appetite, and postprandial bloating. A CT scan showed a solitary, 5.3 Χ 4.4 cm, cystic lesion in the body/tail of the pancreas. Endoscopic retrograde cholangiopancreatography did not show communication between the pancreatic duct and the cystic lesion. Endoscopic ultrasound (EUS) examination revealed a 6.9 Χ 2.4 cm cystic lesion in the body/tail region of the pancreas without septae or solid components. The pancreatic parenchyma, pancreatic duct, and common bile duct were unremarkable. EUS-guided fine needle aspiration (EUS-FNA) was performed using a 22-gauge EchotipTM needle. Only a few dro... CytoJournal journals http://www.medworm.com/rss/comments.php?id=2878045 Sat, 10 Oct 2009 17:26:48 +0100 2878045 http://www.medworm.com/index.php?rid=2878044&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D21%3Bepage%3D21%3Baulast%3DBrimo We describe herein a case of PEL affecting three body cavity sites in an immunocompetent patient. A 69-year-old HIV-negative man presented with upper gastrointestinal bleeding and ascites. An examination of the fluid by cytology showed large atypical lymphocytes with abundant basophilic cytoplasm, either central or eccentric nuclei having irregular outlines, and multiple prominent nucleoli. The neoplastic cells showed positive staining for CD45, CD3, HHV8 latent nuclear antigen (LNA), and Epstein-Barr virus-encoded RNA. A diagnosis of PEL was rendered. Despite chemotherapy and valganciclovir, the disease progressed to involve the pleural and pericardial cavities and the patient died 5 months following the initial diagnosis. Although PEL is a B-cell lymphoma, it is usually of null phenotype... CytoJournal journals http://www.medworm.com/rss/comments.php?id=2878044 Sat, 10 Oct 2009 17:26:48 +0100 2878044 http://www.medworm.com/index.php?rid=2878043&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D20%3Bepage%3D20%3Baulast%3DNgae Ngae Min Yi, Crowder Clinton D, Kjeldahl Klint, Gamez Roberto, Paulson Samantha, McKeon Daniel M, Goyal Priti, Pambuccian Stefan ECytoJournal 2009, 6:20 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2878043 Sat, 10 Oct 2009 17:26:48 +0100 2878043 http://www.medworm.com/index.php?rid=2878042&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D19%3Bepage%3D19%3Baulast%3DRenshaw Conclusion:</b> The correlation of the abnormal rate and the ASC/SIL ratio with sensitivity depends on overall sensitivity. Standards to define minimum screening sensitivity can be defined, but these standards are relatively narrow. These features may limit the utility of these quality measures as surrogates for sensitivity. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2878042 Sat, 10 Oct 2009 17:26:48 +0100 2878042 http://www.medworm.com/index.php?rid=2806093&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D18%3Bepage%3D18%3Baulast%3DSaleh Conclusion:</b> We conclude that galectin-3 is the best single marker in differentiating benign from malignant thyroid lesions with the highest sensitivity and specificity. The galectin-3 + HBME-1 was the best combination for distinguishing benign from malignant lesions. Because they were the best two independent and combined markers, we recommend the use of the galectin-3 + HBME-1 panel to enhance the diagnostic accuracy of follicular-patterned thyroid lesions on FNABs. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2806093 Fri, 18 Sep 2009 16:59:39 +0100 2806093 http://www.medworm.com/index.php?rid=2806092&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D17%3Bepage%3D17%3Baulast%3DAustin Austin R Marshall, Benstein Barbara, Bentz Joel, Bigner Sandra, Freund Gregory G, Rocco Gregory La, Ramzy Ibrahim, Savaloja Lynnette, Shidham Vinod BCytoJournal 2009, 6:17 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2806092 Fri, 18 Sep 2009 16:59:39 +0100 2806092 http://www.medworm.com/index.php?rid=2677084&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D16%3Bepage%3D16%3Baulast%3DThrall Conclusion:</b> Ascites fluid cytology specimens in patients with cirrhosis, even those known or suspected to have HCC, are almost always negative. Atypical cells seen in such specimens should be treated with skepticism since the likelihood that they represent peritoneal spread of HCC is low. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2677084 Fri, 07 Aug 2009 11:29:30 +0100 2677084 http://www.medworm.com/index.php?rid=2673108&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D15%3Bepage%3D15%3Baulast%3DQuddus Conclusions: </b> The ASC-US and AGUS rates did not change statistically before and after the introduction of the Imager in our cytology laboratory. Although use of the Imager did not increase detection of HPV+ ASC-US, it did appear to increase the detection rate of HPV+ AGUS and subsequent abnormal biopsy follow-up rates in all categories. However, the increase in the detection rate did not reach the point of statistical significance (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2673108 Thu, 06 Aug 2009 11:32:13 +0100 2673108 http://www.medworm.com/index.php?rid=2673107&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D14%3Bepage%3D14%3Baulast%3DOkonda Conclusions:</b> This study underscores the need to reduce the incidence of cervical cancer and its precursor lesions in Swaziland women. Based on studies of human papillomavirus (HPV) types in other Southern African countries, current HPV vaccines would reduce the incidence and mortality from cervical cancer in the future, but cervical screening would still be required, both for women already infected with the HPV and for HPV subtypes not covered by current vaccines. The most cost-effective combination of screening modalities such as visual inspection, HPV DNA testing, and cytology should be investigated. Cervical cancer reduction needs to be managed within the greater framework of the HIV/AIDS epidemic. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2673107 Thu, 06 Aug 2009 11:32:13 +0100 2673107 http://www.medworm.com/index.php?rid=2614932&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D13%3Bepage%3D13%3Baulast%3DAnnam Conclusions:</b> Fluorescent microscopy has the advantage of speed and ease of screening, and reduces observer fatigue. The modified fluorescent method was found to be more advantageous than routine cytology and conventional ZN method, particularly in paucibacillary cases. The bacillary positivity rates were higher in the modified fluorescent method than in the ZN method. Hence, the modified fluorescent method can be an adjuvant when used with routine cytology for the identification of AFB. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2614932 Sun, 19 Jul 2009 11:18:51 +0100 2614932 http://www.medworm.com/index.php?rid=2604376&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D12%3Bepage%3D12%3Baulast%3DAustin Austin R Marshall, Zhao ChengquanCytoJournal 2009, 6:12 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2604376 Thu, 16 Jul 2009 11:23:46 +0100 2604376 http://www.medworm.com/index.php?rid=2592519&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D11%3Bepage%3D11%3Baulast%3DNaryshkin Conclusions:</b> Clinicians and staff were receptive to discussions concerning the completion of requisition slips, but laboratory expectations could be better communicated. Requisition slips were properly completed with a high frequency, but the check boxes did not elicit all the information expected, so revision was necessary. The high accuracy of the completion of requisition slips permitted 77% of high-risk Pap tests to be identified via the requisition slip alone. Our findings challenge the conventional anecdotal impressions of "notoriously unreliable" information on Pap test requisition slips, but our experience may not be applicable to other settings. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2592519 Sun, 12 Jul 2009 11:20:35 +0100 2592519 http://www.medworm.com/index.php?rid=2493885&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D10%3Bepage%3D10%3Baulast%3DSantos We report a case of penile metastasis from UC diagnosed by FNAC and describe the cytomorphological findings with an emphasis on cercariform cells. Although not commonly used, FNA of penile nodules can be effective in diagnosing recurrence or metastasis and avoiding surgical procedures, thus being an excellent initial procedure in the diagnostic approach. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2493885 Thu, 25 Jun 2009 08:08:23 +0100 2493885 http://www.medworm.com/index.php?rid=2493884&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D9%3Bepage%3D9%3Baulast%3DGomez-Macias Conclusion:</b> The experience and training of the person performing the aspiration biopsy, as well as immediate evaluation of the material when it is guided, substantially reduces the number of inadequate samples, improving the sensitivity of the method as well as reducing the need for open biopsies to reach a diagnosis. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2493884 Thu, 25 Jun 2009 08:08:23 +0100 2493884 http://www.medworm.com/index.php?rid=2420182&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D8%3Bepage%3D8%3Baulast%3DAhmed Conclusion:</b> Cytological atypia, viral infections, and inflammatory infiltrates were detected after exposure to radiotherapy and/or chemotherapy. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2420182 Tue, 19 May 2009 21:54:55 +0100 2420182 http://www.medworm.com/index.php?rid=2315505&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D7%3Bepage%3D7%3Baulast%3DJimenez-Heffernan Jimenez-Heffernan Jose A, Tejerina Eva, Gonzalez-Peramato Pilar, Vicandi Blanca, Lopez-Garcia AnaCytoJournal 2009, 6:7 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2315505 Thu, 09 Apr 2009 14:35:18 +0100 2315505 http://www.medworm.com/index.php?rid=2247580&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D6%3Bepage%3D6%3Baulast%3DPantanowitz This article critically addresses the emerging role of computer-assisted screening and the application of digital imaging to the field of cytology, including telecytology, virtual microscopy, and the impact of online cytology resources. The role of novel diagnostic techniques like image cytometry is also reviewed. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2247580 Sun, 08 Mar 2009 09:04:26 +0100 2247580 http://www.medworm.com/index.php?rid=2179284&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D5%3Bepage%3D5%3Baulast%3DBatrani Conclusion:</b> This case illustrates that pleomorphic adenoma with squamous metaplasia presents a potential for misinterpretation as mucoepidermoid carcinoma on cytology. We discuss the various pitfalls and the features that are helpful in distinguishing these two lesions. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2179284 Fri, 13 Feb 2009 08:23:14 +0100 2179284 http://www.medworm.com/index.php?rid=2179283&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D4%3Bepage%3D4%3Baulast%3DDavis-Devine Conclusion:</b> When broom + brush combination is compared to broom alone or to spatula + GT brush, the broom + CE brush combination better sampled the endocervical/transformation zone and increased LSIL detection. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2179283 Fri, 13 Feb 2009 08:23:14 +0100 2179283 http://www.medworm.com/index.php?rid=2117971&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D3%3Bepage%3D3%3Baulast%3DJaffar Conclusions:</b> If papillary thyroid carcinoma and Hürthle cell neoplasm are ruled out, our findings indicate that the presence of hemosiderin virtually excludes a clinically significant follicular neoplasm. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2117971 Thu, 22 Jan 2009 03:26:37 +0100 2117971 http://www.medworm.com/index.php?rid=2117970&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D2%3Bepage%3D2%3Baulast%3DWhitaker Conclusions: </b> Using the Cervex brush with conventional cytology significantly decreases inadequate smears and increases TZ sampling when compared to the extended-tip spatula and can offer improved cervical screening in countries unable or unwilling to convert to LBC. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2117970 Thu, 22 Jan 2009 03:26:37 +0100 2117970 http://www.medworm.com/index.php?rid=2117969&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2009%3Bvolume%3D6%3Bissue%3D1%3Bspage%3D1%3Bepage%3D1%3Baulast%3DShah Conclusions: </b> A small subset of primary malignant neoplasms of the thyroid may be misclassified with regard to the type of malignancy on FNA. The majority of primary malignant neoplasms diagnosed on FNA require thyroidectomy. However, initial cytologic misclassification of medullary carcinoma or undifferentiated carcinoma as other malignant neoplasms or vice versa may have an impact on clinical management. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2117969 Thu, 22 Jan 2009 03:26:37 +0100 2117969 http://www.medworm.com/index.php?rid=2068474&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D16%3Bepage%3D16%3Baulast%3DPantanowitz Pantanowitz Liron, Hornish Maryanne, Goulart Robert ACytoJournal 2008, 5:16Automation and emerging information technologies are being adopted by cytology laboratories to augment Pap test screening and improve diagnostic accuracy. As a result, informatics, the application of computers and information systems to information management, has become essential for the successful operation of the cytopathology laboratory. This review describes how laboratory information management systems can be used to achieve an automated and seamless workflow process. The utilization of software, electronic databases and spreadsheets to perform necessary quality control measures are discussed, as well as a Lean production system and Six Sigma approach, to reduce errors in the cytopathology laboratory. (Source:... CytoJournal journals http://www.medworm.com/rss/comments.php?id=2068474 Tue, 30 Dec 2008 03:29:32 +0100 2068474 http://www.medworm.com/index.php?rid=2036985&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D15%3Bepage%3D15%3Baulast%3DShidham Shidham Vinod B, Pitman Martha B, DeMay Richard M, Atkinson Barbara FCytoJournal 2008, 5:15 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=2036985 Wed, 17 Dec 2008 03:30:34 +0100 2036985 http://www.medworm.com/index.php?rid=1986732&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D14%3Bepage%3D14%3Baulast%3DJain Conclusion: </b> The case highlights the potential pitfall of cytology in diagnosing NF, especially because of unusual site and morphologic overlap. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1986732 Thu, 27 Nov 2008 03:58:31 +0100 1986732 http://www.medworm.com/index.php?rid=1852023&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D13%3Bepage%3D13%3Baulast%3DFlanagan Flanagan Melina, Gupta PrabodhCytoJournal 2008, 5:13 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1852023 Sun, 05 Oct 2008 07:05:26 +0100 1852023 http://www.medworm.com/index.php?rid=4063230&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D13%3Bepage%3D13%3Baulast%3DFlanagan Melina Flanagan, Prabodh GuptaCytoJournal 2008 5(1):13-13 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063230 Thu, 02 Oct 2008 23:00:00 +0100 4063230 http://www.medworm.com/index.php?rid=1839179&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D12%3Bepage%3D12%3Baulast%3DJian Jian Bo, Kolansky Ana S, Baloach Zubair W, Gupta Prabodh KCytoJournal 2008, 5:12<i>Entamoeba gingivalis </i> (<i> E. gingivalis</i> ) is a parasitic protozoa of the oral cavity, most often found in gingival tissues around the teeth associated with poor oral hygiene. Here, we report a case of <i> E. gingivalis</i> in a pulmonary CT guided fine needle aspiration material, from a 60-year-old man with newly found lung mass. On site Diff-Quik<sup> ®</sup> smear examination revealed the presence of marked acute inflammation, colonies of actinomyces, and a number of 'large macrophages-like organisms'. Upon examination ... CytoJournal journals http://www.medworm.com/rss/comments.php?id=1839179 Wed, 01 Oct 2008 07:08:55 +0100 1839179 http://www.medworm.com/index.php?rid=4063235&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D12%3Bepage%3D12%3Baulast%3DJian Bo Jian, Ana S Kolansky, Zubair W Baloach, Prabodh K GuptaCytoJournal 2008 5(1):12-12Entamoeba gingivalis ( E. gingivalis ) is a parasitic protozoa of the oral cavity, most often found in gingival tissues around the teeth associated with poor oral hygiene. Here, we report a case of E. gingivalis in a pulmonary CT guided fine needle aspiration material, from a 60-year-old man with newly found lung mass. On site Diff-Quik ® smear examination revealed the presence of marked acute inflammation, colonies of actinomyces, and a number of 'large macrophages-like organisms'. Upon examination of the additional material, organisms morphologically consistent with E. gingivalis were identified. Pulmonary mass resolved after six weeks of treatment with antibiotics (Clindamycin follo... CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063235 Mon, 29 Sep 2008 23:00:00 +0100 4063235 http://www.medworm.com/index.php?rid=1582592&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D11%3Bepage%3D11%3Baulast%3DGupta Gupta Prabodh KCytoJournal 2008 5(1):11-11 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582592 Mon, 07 Jul 2008 06:11:53 +0100 1582592 http://www.medworm.com/index.php?rid=1582591&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D10%3Bepage%3D10%3Baulast%3DThrall Thrall Michael J, Russell Donna K, Bonfiglio Thomas A, Hoda Rana SCytoJournal 2008 5(1):10-10 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582591 Mon, 07 Jul 2008 06:11:53 +0100 1582591 http://www.medworm.com/index.php?rid=1582590&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D9%3Bepage%3D9%3Baulast%3DPattari Pattari Sanjib Kumar, Dey Pranab, Gupta Subhash K, Joshi KusumCytoJournal 2008 5(1):9-9 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582590 Mon, 07 Jul 2008 06:11:53 +0100 1582590 http://www.medworm.com/index.php?rid=1582589&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D8%3Bepage%3D8%3Baulast%3DNaqvi Naqvi Asghar H, Abraham Jerrold L, Kellman Robert M, Khurana Kamal KCytoJournal 2008 5(1):8-8 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582589 Mon, 07 Jul 2008 06:11:53 +0100 1582589 http://www.medworm.com/index.php?rid=1582588&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D7%3Bepage%3D7%3Baulast%3DPusiol Pusiol Teresa, Parolari Anna M, Piscioli Irene, Morelli Luca, Nonno Franca Del, Licci StefanoCytoJournal 2008 5(1):7-7 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582588 Mon, 07 Jul 2008 06:11:53 +0100 1582588 http://www.medworm.com/index.php?rid=1582587&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D6%3Bepage%3D6%3Baulast%3DBaloch Baloch Zubair W, Cibas Edmund S, Clark Douglas P, Layfield Lester J, Ljung Britt-Marie, Pitman Martha Bishop, Abati AndreaCytoJournal 2008 5(1):6-6 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582587 Mon, 07 Jul 2008 06:11:53 +0100 1582587 http://www.medworm.com/index.php?rid=1582586&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D5%3Bepage%3D5%3Baulast%3DPonce-Camacho Ponce-Camacho Marco A, Diaz de Leon-Medina Ricardo, Miranda-Maldonado Ivet, Garza-Guajardo Raquel, Hernandez-Salazar Jorge, Barboza-Quintana OraliaCytoJournal 2008 5(1):5-5 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582586 Mon, 07 Jul 2008 06:11:53 +0100 1582586 http://www.medworm.com/index.php?rid=1582585&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D4%3Bepage%3D4%3Baulast%3DSaleh Saleh Husain A, Clayman Lewis, Masri HaithamCytoJournal 2008 5(1):4-4 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582585 Mon, 07 Jul 2008 06:11:53 +0100 1582585 http://www.medworm.com/index.php?rid=1582584&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D3%3Bepage%3D3%3Baulast%3DSaleh Saleh Husain A, Hammoud Jamal, Zakaria Richard, Khan Aurang ZebCytoJournal 2008 5(1):3-3 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582584 Mon, 07 Jul 2008 06:11:53 +0100 1582584 http://www.medworm.com/index.php?rid=1582583&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D2%3Bepage%3D2%3Baulast%3DTroncone Troncone Giancarlo, Russo Maria, Malapelle Umberto, Accardo Marina, Ferraro Angelo, Cozzolino Immacolata, Palombini LucioCytoJournal 2008 5(1):2-2 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582583 Mon, 07 Jul 2008 06:11:53 +0100 1582583 http://www.medworm.com/index.php?rid=1582582&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D1%3Bepage%3D1%3Baulast%3DBaloch Baloch Zubair W, Barroeta Julieta E, Walsh Janet, Gupta Prabodh K, Livolsi Virginia A, Langer Jill E, Mandel Susan JCytoJournal 2008 5(1):1-1 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1582582 Mon, 07 Jul 2008 06:11:53 +0100 1582582 http://www.medworm.com/index.php?rid=1398011&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F11 . (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1398011 Fri, 25 Apr 2008 04:00:00 +0100 1398011 http://www.medworm.com/index.php?rid=4063240&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D11%3Bepage%3D11%3Baulast%3DGupta Prabodh K GuptaCytoJournal 2008 5(1):11-11 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063240 Thu, 24 Apr 2008 23:00:00 +0100 4063240 http://www.medworm.com/index.php?rid=1395320&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F10 Conclusions: Use of the ThinPrep Imaging System did not appreciably change ASC-US rates or follow-up reflex HPV test results in our laboratory. This demonstrates that the benefits of automated screening may be obtained without increasing the rate of referral to colposcopy for ASC-US follow-up. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1395320 Thu, 24 Apr 2008 04:00:00 +0100 1395320 http://www.medworm.com/index.php?rid=1387252&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F8 We report a case of a Calcium pyrophosphate dihydrate deposition disease (CPPD) presenting as a mass in the parotid and temporomandibular joint (TMJ) that simulated a parotid tumor. A 35 year-old man presented with pain in the left ear area. A CT Scan of the area showed a large, calcified mass surrounding the left condylar head, and extending into the infratemporal fossa. FNA of the mass showed birefringent crystals, most of which were rhomboid with occasional ones being needle shaped, embedded in an amorphous pink substance. Scanning electron microscopy(SEM) with energy dispersive x-ray spectroscopy (EDS) of these crystals showed peaks corresponding to calcium and phosphorus. SEM/EDS is a rapid method of diagnosing calcium pyrophosphate dihydrate deposition disease (CPPD) and an alternati... CytoJournal journals http://www.medworm.com/rss/comments.php?id=1387252 Mon, 21 Apr 2008 04:00:00 +0100 1387252 http://www.medworm.com/index.php?rid=1387251&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F9 In this study, histology proven 71 cases of fine needle aspiration cytology (FNAC) of palpable breast lesions were selected. There were 30 invasive carcinomas (24 infiltrating duct carcinoma and 6 infiltrating lobular carcinoma), 25 cases of benign lesion (21 fibroadenomas and 4 fibrocystic lesions) and 11 proliferative breast diseases (other than carcinoma in situ) and five cases of carcinoma in situ. The number of ME cells were estimated in respect to 1000 ductal cells. In every case at least 20 high power fields (x 40) were studied. Quantitative estimation of ME cell was correlated with the final diagnosis. Corresponding histopathology cases were also evaluated for diagnostic confirmation along with the pattern of distribution of ME cells. The ME cells were also quantitated on histopath... CytoJournal journals http://www.medworm.com/rss/comments.php?id=1387251 Mon, 21 Apr 2008 04:00:00 +0100 1387251 http://www.medworm.com/index.php?rid=1377165&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F7 Conclusions: PBs in the cervicovaginal smears are a rare finding, associated more often with benign conditions than with malignancies. Moreover, to our knowledge, our case of primary ovarian psammocarcinoma is the first report in which the presence of malignant cells and PBs in the cervicovaginal and endometrial smears represents the first manifestation of disease. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1377165 Wed, 16 Apr 2008 04:00:00 +0100 1377165 http://www.medworm.com/index.php?rid=1354521&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F6 No abstract (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1354521 Mon, 07 Apr 2008 04:00:00 +0100 1354521 http://www.medworm.com/index.php?rid=4542121&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2008%3Bvolume%3D5%3Bissue%3D1%3Bspage%3D5%3Bepage%3D5%3Baulast%3DPonce%252DCamacho Conclusion: Congenital ganglioneuroma of the cervical region is an uncommon soft tissue benign neoplasm of neuroblastic origin, and it should be considered in the differential diagnosis of head and neck pediatric soft tissue tumors. Fine needle aspiration biopsy technique is a reliable method that can be used with confidence when dealing with pediatric soft tissue tumors. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4542121 Sun, 30 Mar 2008 00:00:00 +0100 4542121 http://www.medworm.com/index.php?rid=1333145&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F4 Conclusion: FNA biopsy of intraoral and oropharyngeal masses is a valuable procedure for the initial evaluation of various lesions. It provides helpful information about these lesions and avoids hasty or unnecessary surgical biopsy. It is a rapid and relatively noninvasive procedure. Furthermore, aspiration biopsy is an important tool in the diagnosis and management of these lesions, both neoplastic and non-neoplastic, and can be sometimes complemented by ancillary studies for more accurate interpretation. However, its sensitivity in the diagnosis of malignancy is lower than that of histologic samples. This is probably due to the superficial nature and small size of these lesions, the limited space for maneuvering the needle and difficulty in immobilizing the lesion to obtain adequate samp... CytoJournal journals http://www.medworm.com/rss/comments.php?id=1333145 Fri, 28 Mar 2008 04:00:00 +0100 1333145 http://www.medworm.com/index.php?rid=1326059&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F3 Conclusion: In thyroid FNAB cases, TP slide preparation is superior to CB slide preparation and is more likely to have greater cellularity for diagnosis and detect atypical/ neoplastic thyroid lesions, particularly those of follicular cell origin. Furthermore, TP slides appear to detect helpful diagnostic cytologic features and should be considered complementary to, rather than replacing, direct smears. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1326059 Tue, 25 Mar 2008 04:00:00 +0100 1326059 http://www.medworm.com/index.php?rid=1312645&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F2 Papillary thyroid carcinoma (PTC) composed by predominant solid areas is diagnosed as a distinct variant on histological samples. Here we present a case of PTC recognized preoperatively by fine needle cytology as a solid variant. This diagnosis was made by combining cytology with the detection of the BRAFVK600-1E mutation, the molecular hallmark of the solid variant of PTC. Histological and molecular evaluation of the surgical specimen confirmed this pre-operative diagnosis. Thus combining cytology to BRAF molecular analysis is useful to refine the cytological diagnosis of this variant also on FNC specimens. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=1312645 Wed, 19 Mar 2008 04:00:00 +0100 1312645 http://www.medworm.com/index.php?rid=1190247&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F5%2F1%2F1 IntroductionThe most common site for the metastasis of papillary carcinoma of the thyroid (PTC) is regional lymph nodes. Ultrasound (US) imaging may identify abnormal appearing lymph nodes, suspicious for PTC recurrence. Although fine needle aspiration biopsy (FNAB) of abnormal lymph nodes is often diagnostic of recurrence, small or cystic lymph nodes may be non-diagnostic due to lack of tumor cells. The measurement of thyroglobulin (TG) levels in FNAB specimens from lymph nodes suspicious for recurrent PTC can serve as an adjunct to the cytologic diagnosis. Materials and methods: 115 abnormal appearing lymph nodes were aspirated under ultrasound guidance in 89 patients with history of thyroid carcinoma. In addition to obtaining material for cytologic interpretation, an additional aspirate... CytoJournal journals http://www.medworm.com/rss/comments.php?id=1190247 Thu, 31 Jan 2008 05:00:00 +0100 1190247 http://www.medworm.com/index.php?rid=993579&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F20 Conclusions: FNAC is fairly specific and sensitive in STT diagnoses for primary, recurrent and metastatic lesions. The cytological types, especially round cell and pleomorphic sarcomas, can be quickly identified. Clinicopathological correlation with ICC as an adjunct, are valuable in exact sub typing. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=993579 Wed, 31 Oct 2007 04:00:00 +0100 993579 http://www.medworm.com/index.php?rid=886621&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F19 This article gives background perspective on the development of the Universal Protocol. It also elaborates the JCAHO National Patients Safety Goals regarding the performance of fine needle aspirations. The compliance with the Universal Protocol for performance of fine needle aspirations is now mandated for all cytopathologists who perform fine needle aspirations and this present paper provides a guideline for fulfilling the requirements of the universal protocol for practicing cytopathologists. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=886621 Thu, 20 Sep 2007 04:00:00 +0100 886621 http://www.medworm.com/index.php?rid=4063223&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D19%3Bepage%3D19%3Baulast%3DSiddiqui This article gives background perspective on the development of the Universal Protocol. It also elaborates the JCAHO National Patients Safety Goals regarding the performance of fine needle aspirations. The compliance with the Universal Protocol for performance of fine needle aspirations is now mandated for all cytopathologists who perform fine needle aspirations and this present paper provides a guideline for fulfilling the requirements of the Universal Protocol for practicing cytopathologists. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063223 Wed, 19 Sep 2007 23:00:00 +0100 4063223 http://www.medworm.com/index.php?rid=4029150&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D19%3Bepage%3D19%3Baulast%3DSiddiqui This article gives background perspective on the development of the Universal Protocol. It also elaborates the JCAHO National Patients Safety Goals regarding the performance of fine needle aspirations. The compliance with the Universal Protocol for performance of fine needle aspirations is now mandated for all cytopathologists who perform fine needle aspirations and this present paper provides a guideline for fulfilling the requirements of the Universal Protocol for practicing cytopathologists. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029150 Wed, 19 Sep 2007 23:00:00 +0100 4029150 http://www.medworm.com/index.php?rid=883982&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F18 Conclusions: The cytomorphology of desmoplastic melanoma shows excellent correlation between cytomorphology of single spindle cells on conventional smears and on ThinPrep slides. The major difference noted on ThinPrep slides was attenuated nuclear and cytoplasmic detail of spindle cells embedded in fibrous stoma. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=883982 Wed, 19 Sep 2007 04:00:00 +0100 883982 http://www.medworm.com/index.php?rid=4029154&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D18%3Bepage%3D18%3Baulast%3DVan Conclusion: The cytomorphology of desmoplastic melanoma shows excellent correlation between cytomorphology of single spindle cells on conventional smears and on ThinPrep slides. The major difference noted on ThinPrep slides was attenuated nuclear and cytoplasmic detail of spindle cells embedded in fibrous stoma. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029154 Tue, 18 Sep 2007 23:00:00 +0100 4029154 http://www.medworm.com/index.php?rid=848675&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F17 Conclusions: Myelomatous pleural effusion as an initial presentation although extremely rare, should always be considered in presence of atypical plasma cells irrespective of age. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=848675 Fri, 07 Sep 2007 04:00:00 +0100 848675 http://www.medworm.com/index.php?rid=801700&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F16 The Pap smear is one of the modern success stories in the field of preventive medicine. Since its introduction as a screening test, there has been a dramatic reduction in the incidence of cervical cancer. However, the search for a better screening test continues. The new technologies, including liquid-based cytology (LBC), Human Papilloma Virus (HPV) testing and automated or machine-assisted screening have been introduced. However, there is continuous debate about whether society's limited resources are better spent on reaching the underserved rather than on these technologies. Another question is whether these technologies create yet another kind of disparity in delivering preventive care. For example, despite the wide use of LBC (99% of tests submitted to our laboratory are LBC), convent... CytoJournal journals http://www.medworm.com/rss/comments.php?id=801700 Thu, 16 Aug 2007 04:00:00 +0100 801700 http://www.medworm.com/index.php?rid=735171&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F15 Conclusion: The atypical presentation of the case made the cytological diagnosis rather challenging. Clear cell sarcoma should be considered when cytology of a soft-tissue tumor shows uncharacteristically high cellularity and relatively uniform cells with macronucleoli. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=735171 Sun, 15 Jul 2007 04:00:00 +0100 735171 http://www.medworm.com/index.php?rid=4029166&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D15%3Bepage%3D15%3Baulast%3DMurugan Conclusion: The atypical presentation of the case made the cytological diagnosis rather challenging. Clear cell sarcoma should be considered when cytology of a soft-tissue tumor shows uncharacteristically high cellularity and relatively uniform cells with macronucleoli. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4029166 Sat, 14 Jul 2007 23:00:00 +0100 4029166 http://www.medworm.com/index.php?rid=711990&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F14 Conclusion: amelanotic melanoma may be successfully diagnosed on LBP cytological preparations. Thin layer preparations may enhance the diagnostic cytomorphological clues to its diagnosis and may permit an adequate immunocytochemical characterization of the neoplasm. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=711990 Tue, 03 Jul 2007 04:00:00 +0100 711990 http://www.medworm.com/index.php?rid=4063225&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D14%3Bepage%3D14%3Baulast%3DFulciniti Conclusion: amelanotic melanoma may be successfully diagnosed on LBP cytological preparations. Thin layer preparations may enhance the diagnostic cytomorphological clues to its diagnosis and may permit an adequate immunocytochemical characterization of the neoplasm (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063225 Mon, 02 Jul 2007 23:00:00 +0100 4063225 http://www.medworm.com/index.php?rid=690189&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F13 Conclusion: Pancreatic adenocarcinoma showed positive immunohistochemical staining for SMAD4 in 80%, CK19 in 100% and CA19-9 in 100% of the selected cases. These markers, when used as a panel, may confirm the diagnosis of pancreatic adenocarcinoma in fine needle aspiration samples, and help in differentiating from metastatic adenocarcinoma. This may help in determination of appropriate surgical and chemotherapeutic options. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=690189 Fri, 22 Jun 2007 04:00:00 +0100 690189 http://www.medworm.com/index.php?rid=4063229&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D13%3Bepage%3D13%3Baulast%3DZapata Conclusion :Pancreatic adenocarcinoma showed positive immunohistochemical staining for SMAD4 in 80%, CK19 in 100% and CA19-9 in 100% of the selected cases. These markers, when used as a panel, may confirm the diagnosis of pancreatic adenocarcinoma in fine needle aspiration samples, and help in differentiating from metastatic adenocarcinoma. This may help in determination of appropriate surgical and chemotherapeutic options. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063229 Thu, 21 Jun 2007 23:00:00 +0100 4063229 http://www.medworm.com/index.php?rid=661094&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F12 This year CytoJournal celebrates the second full year of publication with its Best of CytoJournal: 2006. Like last year, it recognizes the work of the authors in thyroid FNAB. And, importantly, this year's award, which was handed out at USCAP, was endowed by a gift from the Pathikonda family. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=661094 Mon, 11 Jun 2007 04:00:00 +0100 661094 http://www.medworm.com/index.php?rid=655802&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F11 Background: The combination of cytology and biopsies improves the recognition and typing of small cell (SCLC) versus non small cell (NSCLC) lung cancers in the fiberoptic bronchoscopy assessment of centrally located tumours. Methods: We studied whether bronchial aspirates performed before biopsies (BA) and washings performed after biopsies (BW) could increase the diagnostic yield of fiberoptic bronchoscopy. A series of 334 consecutive samples taken in patients with positive fiberoptic bronchoscopy findings was studied. Two hundred primary tumours were included in the study. The actual diagnosis was based on surgical tissue specimen analysis and/or imaging techniques. The typing used was that of the 1999 WHO/IASLC classification. Results: The diagnosis of malignancy and tumour typing were ... CytoJournal journals http://www.medworm.com/rss/comments.php?id=655802 Mon, 04 Jun 2007 04:00:00 +0100 655802 http://www.medworm.com/index.php?rid=581228&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F10 Conclusion: Despite the availability of several tests for diagnosis of LT, FNAC remains the gold standard. The grades of thyroiditis at cytology however do not correlate with clinical, biochemical, radionuclide and ultrasonographic parameters. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=581228 Mon, 30 Apr 2007 04:00:00 +0100 581228 http://www.medworm.com/index.php?rid=4063244&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D10%3Bepage%3D10%3Baulast%3DBhatia Conclusion: Despite the availability of several tests for diagnosis of LT, FNAC remains the gold standard. The grades of thyroiditis at cytology however do not correlate with clinical, biochemical, radionuclide and ultrasonographic parameters. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063244 Sun, 29 Apr 2007 23:00:00 +0100 4063244 http://www.medworm.com/index.php?rid=557605&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F9 Conclusions: Cytology provides valuable information to the clinician to make an informed decision regarding appropriate therapy. We conclude that time-consuming and costly investigations may be reduced by choosing FNAB as the initial pathological diagnostic method for skeletal lesions of unknown origin. The choice of radiological examinations, laboratory tests and surgical biopsies can be determined after the FNAB diagnosis. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=557605 Tue, 17 Apr 2007 04:00:00 +0100 557605 http://www.medworm.com/index.php?rid=4063252&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D8%3Bepage%3D8%3Baulast%3DMahoney Barbara MahoneyCytoJournal 2007 4(1):8-8 (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063252 Thu, 12 Apr 2007 23:00:00 +0100 4063252 http://www.medworm.com/index.php?rid=484764&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F7 Conclusion: LSIL-H overlapped with LSIL and ASC-H, but was distinct from HSIL. A management algorithm comparable to ASC-H and HSIL appears to be appropriate in LSIL-H cases. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=484764 Tue, 20 Mar 2007 04:00:00 +0100 484764 http://www.medworm.com/index.php?rid=4063256&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Farticle.asp%3Fissn%3D1742-6413%3Byear%3D2007%3Bvolume%3D4%3Bissue%3D1%3Bspage%3D7%3Bepage%3D7%3Baulast%3DShidham Conclusion: LSIL-H overlapped with LSIL and ASC-H, but was distinct from HSIL. A management algorithm comparable to ASC-H and HSIL appears to be appropriate in LSIL-H cases. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=4063256 Tue, 20 Mar 2007 00:00:00 +0100 4063256 http://www.medworm.com/index.php?rid=404469&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F6 Conclusions: The overall performance of the TIS in our lab appears to be highly satisfactory in terms of improving sensitivity in screening cervical precursor lesions. The increased accuracy of detection of HSIL indicates a positive impact of the TIS in our laboratory. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=404469 Thu, 08 Feb 2007 07:00:00 +0100 404469 http://www.medworm.com/index.php?rid=456983&cid=s_28442_32_f&fid=28442&url=http%3A%2F%2Fwww.cytojournal.com%2Fcontent%2F4%2F1%2F6 Conclusion: The overall performance of the TIS in our lab appears to be highly satisfactory in terms of improving sensitivity in screening cervical precursor lesions. The increased accuracy of detection of HSIL indicates a positive impact of the TIS in our laboratory. (Source: CytoJournal) CytoJournal journals http://www.medworm.com/rss/comments.php?id=456983 Thu, 08 Feb 2007 05:00:00 +0100 456983