Der Ophthalmologe via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Der Ophthalmologe' source. Thu, 18 Mar 2010 15:03:06 +0100 [Modeling in value-based medicine.] http://www.medworm.com/index.php?rid=3332297&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20195613%26dopt%3DAbstract Authors: Neubauer AS, Hirneiß C, Kampik A Modeling plays an important role in value-based medicine (VBM). It allows decision support by predicting potential clinical and economic consequences, frequently combining different sources of evidence. Based on relevant publications and examples focusing on ophthalmology the key economic modeling methods are explained and definitions are given. The most frequently applied model types are decision trees, Markov models, and discrete event simulation (DES) models. Model validation includes besides verifying internal validity comparison with other models (external validity) and ideally validation of its predictive properties. The existing uncertainty with any modeling should be clearly stated. This is true for economic modeling in VBM as well... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3332297 Wed, 03 Mar 2010 00:00:00 +0100 3332297 [Methods for estimating personal costs of disease using retinal diseases as an example.] http://www.medworm.com/index.php?rid=3332296&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20195614%26dopt%3DAbstract CONCLUSIONS: Prevention or delay of visual disability and blindness caused by AMD or other retinal diseases and thus ensuring independence is not only relevant from a medical perspective but also from a health economic perspective. Against the background of a relative shortage of resources, costs should be reduced regardless of whether they are personal or societal costs. PMID: 20195614 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3332296 Wed, 03 Mar 2010 00:00:00 +0100 3332296 [The IOL-Vip system : Principles and clinical application.] http://www.medworm.com/index.php?rid=3314934&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20186545%26dopt%3DAbstract Authors: Khoramnia R, von Mohrenfels CW, Salgado JP, Schweiger B, Engel M, Hadeler J, Lohmann CP There are various retinal disorders that cause macular degeneration. However, age-related macular degeneration (ARMD) is the main cause of legal blindness in developed countries. Even today the end stage of this disease can often not be avoided. Patients suffer from central scotoma and severe vision loss. Low vision aids may help in certain situations, but these devices are often functionally and cosmetically inadequate. The implantation of the IOL-Vip system is a new surgical alternative. The lens system consists of a high negative power lens (-64 D) which is implanted in the capsular bag and a high positive power lens (+53 D) which is implanted in the anterior chamber. An intraocular Gali... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3314934 Sat, 27 Feb 2010 00:00:00 +0100 3314934 [Value-based medicine for glaucoma.] http://www.medworm.com/index.php?rid=3314935&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20182735%26dopt%3DAbstract Authors: Hirneiß C, Kampik A, Neubauer AS The application of value-based medicine (VBM) tenets in the area of glaucoma research requires valid and reliable data concerning the quality of life with glaucoma. A multitude of instruments for measuring quality of life of patients with glaucoma have been employed in the past. Any instrument used would need to capture peripheral vision loss and its influence on patient-reported quality of life as this is one of the hallmarks of this disease. Cost-utility analyses can then be based on the reported quality of life and the cost of glaucoma therapy. Several cost-utility analyses have been applied in the field of glaucoma screening as well as treating ocular hypertension and based on this a recommendation regarding population subgroups which ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3314935 Fri, 26 Feb 2010 00:00:00 +0100 3314935 [Rational antibiotic therapy in ophthalmology.] http://www.medworm.com/index.php?rid=3267379&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20145935%26dopt%3DAbstract Authors: Behrens-Baumann W, Frank U, Neß T Bacterial infections can affect all structures of the eye. In most cases, infections of the ocular surface are treatable with topical antibiotics, whereas intraocular infections need a combined treatment with intraocular and systemic antibiotics. Localisation, severity, expected microorganisms, and possible consequences of the infection lead to the appropriate therapy. Unwarranted use of antibiotic substances for prophylaxis or treatment of nonbacterial infection should be avoided, especially because of possible selection of multiresistant microorganisms. PMID: 20145935 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3267379 Thu, 11 Feb 2010 00:00:00 +0100 3267379 [Correction of corneal astigmatism with toric lenses : Theory and clinical aspects.] http://www.medworm.com/index.php?rid=3259713&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20140618%26dopt%3DAbstract Authors: Langenbucher A, Viestenz A, Szentmáry N, Viestenz A, Eppig T, Seitz B In the last decades, the implantation of pseudophakic and phakic toric lenses has become widespread for correcting corneal astigmatism: in cataract surgery cases with implantation of a posterior chamber lens and in refractive surgery cases with implantation of phakic lenses. The purpose of this educational and training article is to familiarize the reader with the application of pseudophakic and phakic toric lenses, to show which parameters are necessary for calculating toric lenses, to present a matrix-based calculation scheme for pseudophakic and phakic toric lenses, to explicitly demonstrate the step-by-step calculations with clinical examples, and to show the impact of lens dislocation (especially r... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3259713 Sun, 07 Feb 2010 00:00:00 +0100 3259713 [Technologies, techniques and tactics for micro-incision cataract surgery.] http://www.medworm.com/index.php?rid=3240496&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130886%26dopt%3DAbstract Authors: Fabian E, Maier M Ultra-sound (US) phaco-emulsification is currently developing from a small incision to a micro-incision cataract surgery (MICS). Improvements in machine technologies with new US delivery modes with better control of irrigation and aspiration, with smaller phacotips and sleeves and with new intraocular lenses and injector systems for implantations through incisions less than 2 mm wide. Therefore, the most suitable method for surgery can be selected for each individual eye situation. Further improvements of intra-ocular lenses for implantation through incisions less than 2 mm wide would be desirable. PMID: 20130886 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3240496 Fri, 05 Feb 2010 00:00:00 +0100 3240496 [Diffuse stromal corneal opacity and alterations of the hands.] http://www.medworm.com/index.php?rid=3233290&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20119743%26dopt%3DAbstract Authors: Lanzl IM, Seidova SF, Erben A, Thürmel K, Kotliar K Bilateral stromal corneal opacity is a differential diagnostic challenge for ophthalmologists. In this article 2 female patients aged 30 and 36 years old, respectively, with different degrees of expression of stromal diffuse corneal opacity will be presented. Patient 1 was of short stature (114 cm) and patient 2 was 172 cm in size. Both patients exhibited altered joint structures of the hands and feet and diffuse stromal corneal opacity. Furthermore, patient 1 had both mitral and aortal insufficiencies and patient 2 an aorta insufficiency. The stromal diffuse corneal opacity was indicative of Schleie syndrome. For patients with reduced vision a lamellary keratoplasty is to be recommended. PMID: 20119743 [PubMed - as ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3233290 Sun, 31 Jan 2010 00:00:00 +0100 3233290 [Bilateral hyposphagma.] http://www.medworm.com/index.php?rid=3233289&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20119834%26dopt%3DAbstract We present the case of an 85-year-old woman who presented with red eyes bilaterally. The right eye had been red for 2 months, and the left one for a shorter time. The ophthalmologic examination showed severely congested episcleral vessels in both eyes, reduction of visual acuity, hyperemia of iris vessels, and pigment epithelium detachment. Ocular tension was within normal range. Both eyes showed impaired ocular movement, and the left eye had an abducens paresis. Our strong suspicion of carotid-cavernous sinus fistula was confirmed through a computed tomographic perfusion study; the previously conducted magnetic resonance examination of the cerebrum was without result. PMID: 20119834 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3233289 Sun, 31 Jan 2010 00:00:00 +0100 3233289 [Soft oculopression.] http://www.medworm.com/index.php?rid=3223569&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20107809%26dopt%3DAbstract CONCLUSION: The method of soft oculopression can be recommended because of its excellent self-calibrating tension reducing effect combined with a pleasant and easy application. PMID: 20107809 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3223569 Fri, 29 Jan 2010 00:00:00 +0100 3223569 [Incisions for biaxial and coaxial microincision cataract surgery.] http://www.medworm.com/index.php?rid=3223568&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20107810%26dopt%3DAbstract Authors: Müller M, Kohnen T Microincision cataract surgery (MICS) represents a new level in the development of cataract surgery. Phacoemulsification with intraocular lens (IOL) implantation via incisions of </=2 mm may be performed by the coaxial approach, such as conventional phacoemulsification but with a smaller diameter of the phaco tip (C-MICS), or by the biaxial approach, with separation of the phaco tip and irrigation (B-MICS). Compared with standard small-incision cataract surgery, the advantages of MICS are less corneal astigmatism and fewer corneal surface irregularities, with favorable implications for visual quality and early rehabilitation. In the effort toward smaller incisions, special interest should be given to wound integrity, especially regarding the risk of ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3223568 Fri, 29 Jan 2010 00:00:00 +0100 3223568 [Fundus leucaemicus as first manifestation of chronic myeloid leukemia : Diagnosis and monitoring with OCT under treatment with imatinib and interferon-alpha.] http://www.medworm.com/index.php?rid=3223565&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20108097%26dopt%3DAbstract Authors: Chankiewitz E, Scholz GA, Spriewald BM, Mackensen A, Bergua A Fundus leucaemicus with reduction of visual acuity can be one of the first signs of chronic myeloid leukemia (CML). The ocular manifestations are unspecific, but characteristic for severe systemic diseases. Optical coherence tomography (OCT) is helpful for documentation and quantification of the pathological retinal changes. However, peripheral blood counts and differential haemograms are seminal for the diagnosis of CML and can be important for survival. First line therapy for CML is the application of the tyrosine kinase inhibitor imatinib (Glivec(R)). Ophthalmological adverse effects of this therapy, such as periorbital edema, are possible. Therefore regular ophthalmic monitoring should be performed. PMID: 20... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3223565 Fri, 29 Jan 2010 00:00:00 +0100 3223565 [Intraocular lenses for microincisional cataract surgery.] http://www.medworm.com/index.php?rid=3223567&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20107811%26dopt%3DAbstract Authors: Kohnen T, Klaproth OK Incision size in micro-incisional cataract surgery (MICS) is dependent on the minimal size of the folded or rolled intraocular lens (IOL) during implantation and thus the outer diameter of the injector system used. At present implantations through incisions <2.0 mm are possible. MICS IOLs have to be optimized for this small dimension in terms of material and lens body design. Compared to standard procedures, MICS induces little astigmatism and higher order aberrations. Thus MICS procedures provide better predictability in terms of postoperative refractive results. This is of special interest when implanting advanced optic designs, such as aspheric, toric or multifocal IOLs. PMID: 20107811 [PubMed - as supplied by publisher] (Source: Der Ophthalmolo... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3223567 Thu, 28 Jan 2010 00:00:00 +0100 3223567 [MICS - micro incision cataract surgery.] http://www.medworm.com/index.php?rid=3223566&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20107812%26dopt%3DAbstract Authors: Kohnen T PMID: 20107812 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3223566 Thu, 28 Jan 2010 00:00:00 +0100 3223566 [Choroiditis.] http://www.medworm.com/index.php?rid=3176422&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20069302%26dopt%3DAbstract This article summarizes the different entities of choroiditis, their differential diagnosis and the main treatment principles. PMID: 20069302 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3176422 Thu, 14 Jan 2010 00:00:00 +0100 3176422 [Intra-ocular pressure during and after playing high and low resistance wind instruments.] http://www.medworm.com/index.php?rid=3167997&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20063000%26dopt%3DAbstract CONCLUSION: IOP changes found in particular during laboured playing with high resistance wind instruments could be a risk factor for glaucomatous optic nerve damage. PMID: 20063000 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3167997 Sun, 10 Jan 2010 00:00:00 +0100 3167997 [Femtosecond laser-assisted penetrating keratoplasty.] http://www.medworm.com/index.php?rid=3111856&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024559%26dopt%3DAbstract Authors: Birnbaum F, Maier P, Reinhard T The femtosecond laser technique allows completely new trephination methods in penetrating keratoplasty with profiles in the graft and the host cornea. The most common so-called profiled trephinations are the top hat and mushroom profiles. Due to the profile it is easier to get a watertight wound closure intraoperatively and due to the larger wound surface the wound healing is faster and more stable. This will possibly allow an earlier suture removal with final visual rehabilitation. First clinical results show that femtosecond laser-assisted penetrating keratoplasty is a safe surgical procedure. The long term results after complete suture removal will show whether the astigmatism results are better than those of conventional trephination techniq... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111856 Sun, 20 Dec 2009 00:00:00 +0100 3111856 [Perioperative conversion of oral anticoagulants to heparin (bridging) in ophthalmic medicine.] http://www.medworm.com/index.php?rid=3111855&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024560%26dopt%3DAbstract Authors: Feltgen N, Pielen A, Hattenbach LO, Geisen U, Heinz J Since topical anesthesia was introduced in ophthalmic surgery, anticoagulation therapy can often be used in patients with thromboembolic risk. But some surgical procedures with an increased risk for intraoperative bleeding necessitate changing a patient's Coumadin therapy to heparin. To reduce intraoperative bleeding and perioperative thromboembolic complications, ophthalmologists and referring general practitioners should cooperate closely. PMID: 20024560 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111855 Sun, 20 Dec 2009 00:00:00 +0100 3111855 [Visual diagnosis : Waardenburg syndrome.] http://www.medworm.com/index.php?rid=3111854&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024561%26dopt%3DAbstract CONCLUSION: According to the major and minor criteria defined by the Waardenburg consortium our patient showed the major criteria of WS1, i.e. hearing loss, hypopigmentation of the pigment epithelium of the iris and dystopic canthi. Diagnosis of WS is usually based on the clinical presentation. An additional molecular genetic analysis is possible. PMID: 20024561 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111854 Sun, 20 Dec 2009 00:00:00 +0100 3111854 [Morbus Morbihan : A rare cause of edematous swelling of the eyelids.] http://www.medworm.com/index.php?rid=3111853&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024562%26dopt%3DAbstract We report the first case of morbus Morbihan in the ophthalmic literature. A 53-year-old woman complained of erythematous and edematous eyelids which caused a significant visual field defect for 4 years. The typical clinical picture, histological findings and the exclusion of several differential diagnoses led to the diagnosis of morbus Morbihan. Oral rosacea treatment did not result in any improvement, therefore, eyelid reduction surgery followed by lymphatic drainage was performed. Apart from cosmetic improvement a significant reduction of visual field defects was observed postoperatively. PMID: 20024562 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111853 Sun, 20 Dec 2009 00:00:00 +0100 3111853 [Solitary synchronous intraocular metastasis of a peripheral non-small cell lung cancer : A multidisciplinary approach with curative intention.] http://www.medworm.com/index.php?rid=3111852&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024563%26dopt%3DAbstract Authors: Hohls M, Siebke A, Gokel M, Knorr M, Streuter M, Haas V A solitary synchronous distant metastasis of newly diagnosed non-small cell lung cancer (NSCLC) occurs in only a small number of patients. The available literature suggests a significant rise in long-term survival for these patients when resection of the bronchial carcinoma and the metastasis are feasible and performed. To demonstrate a multidisciplinary concept, we present the case of a patient with a peripheral NSCLC and a solitary synchronous intraocular metastasis. To our knowledge, this concept with curative intention has not been published before regarding a patient with an intraocular metastasis. PMID: 20024563 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111852 Sun, 20 Dec 2009 00:00:00 +0100 3111852 [Laser embolectomy for central retinal artery occlusion.] http://www.medworm.com/index.php?rid=3111851&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024564%26dopt%3DAbstract We describe a case of successful Nd:YAG laser embolectomy in a patient with occlusions of the retinal artery affecting the macula and reducing visual acuity. The treatment can only be recommended in cases with a visible embolus and short duration of symptoms. PMID: 20024564 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111851 Sun, 20 Dec 2009 00:00:00 +0100 3111851 [Value-based medicine in ophthalmology.] http://www.medworm.com/index.php?rid=3111850&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024565%26dopt%3DAbstract Authors: Finger RP PMID: 20024565 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111850 Sun, 20 Dec 2009 00:00:00 +0100 3111850 [Patient-reported and patient-weighted outcomes in ophthalmology.] http://www.medworm.com/index.php?rid=3111849&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20024566%26dopt%3DAbstract This article defines core terms in CER. The concept of patient-relevant (or patient-important) outcomes is distinguished from patient-reported outcomes (PRO) by means of examples in the field of ophthalmology. In order to be able to give a consistant recommendation if an intervention leads to conflicting results for different outcomes (trade-off), a ranking of outcomes will be necessary. Examples of studies in glaucoma patients are provided that demonstrate the possibilities of ranking of outcomes based on patient preferences. PMID: 20024566 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3111849 Sun, 20 Dec 2009 00:00:00 +0100 3111849 [Simulation of corneal epithelial injuries by mechanical and corrosive damage : Influence of fetal bovine serum and dexpanthenol on epithelial regeneration in a cell culture model.] http://www.medworm.com/index.php?rid=3106959&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20020304%26dopt%3DAbstract CONCLUSION: The described model allowed simulation of corneal epithelial injury and its regeneration, whereby the influence of the serum content and the kind of injury could be determined. PMID: 20020304 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3106959 Sat, 19 Dec 2009 00:00:00 +0100 3106959 [Tapetoretinal dystrophy and unusual facial features in an 8-year-old boy.] http://www.medworm.com/index.php?rid=3102043&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20013277%26dopt%3DAbstract Authors: Kramer S, Seitz B, Käsmann-Kellner B An 8-year-old boy showed multiple cardiovascular and urinogenital anomalies, neurological problems as well as endocrinological abnormalities even shortly after birth. The patient had ophthalmological peculiarities, such as eyelid cleft configuration, tapetoretinal dystrophy, retinal visual atrophy, early childhood converging strabismus with varying angle relationships, nystagmus, light sensitivity and substantial visual deficits. Finally a Kabuki syndrome could be confirmed by human genetic investigations (8q22-23 triplication). PMID: 20013277 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3102043 Thu, 17 Dec 2009 00:00:00 +0100 3102043 [What is the significance of vitamins for the eye.] http://www.medworm.com/index.php?rid=3102044&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20012993%26dopt%3DAbstract Authors: Mrowietz-Ruckstuhl B, Großklaus R PMID: 20012993 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3102044 Wed, 16 Dec 2009 00:00:00 +0100 3102044 [Endocyclophotocoagulation for the treatment of glaucoma.] http://www.medworm.com/index.php?rid=3079628&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19997737%26dopt%3DAbstract Authors: Neuburger M, Böhringer D, Jordan JF Cyclophotocoagulation is the standard cyclodestructive procedure for treating patients with refractory glaucoma. In addition to transscleral cyclophotocoagulation, endoscopically controlled cyclophotocoagulation (ECPC) is a relatively new method, introduced in the 1990s. Its clinical and technical background is outlined in this article. ECPC allows direct visualization of the ciliary body and better control of the applied laser energy. Therefore, ECPC has been described as being more effective and safer than the transscleral approach. Our own retrospective ECPC data, however, do not indicate that this method can sufficiently decrease intraocular pressure. The indication for the invasive procedure of endoscopic cyclophotocoagulation is t... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3079628 Wed, 09 Dec 2009 00:00:00 +0100 3079628 [Laser trabeculoplasty for glaucoma therapy.] http://www.medworm.com/index.php?rid=3079627&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19997738%26dopt%3DAbstract Authors: Eckert S PMID: 19997738 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3079627 Wed, 09 Dec 2009 00:00:00 +0100 3079627 [A comparative in vitro analysis of primary and immortalized keratocytes.] http://www.medworm.com/index.php?rid=3071812&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19967540%26dopt%3DAbstract CONCLUSION: HCKi are more resistant and proliferative than HCKp but they can be used in preliminary experiments as an alternative to primary cells in for example toxicity studies if the detectable differences between the two cell lines, such as the capacity for proliferation and reaction to agents are taken into consideration. PMID: 19967540 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3071812 Sun, 06 Dec 2009 00:00:00 +0100 3071812 [Diagnostics and differential diagnosis of acute retinal necrosis.] http://www.medworm.com/index.php?rid=3053349&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19949951%26dopt%3DAbstract Authors: Pleyer U, Metzner S, Hofmann J Multiple viruses have been identified as causative agents in acute retinal necrosis (ARN). Retinal biopsies, analysis of intraocular antibody synthesis, and polymerase chain reaction (PCR) have identified varicella zoster virus, herpes simplex virus types 1 and 2, and cytomegalovirus. The differential diagnosis of ARN includes atypical ocular toxoplasmosis, some white dot syndromes, and other forms of retinal vasculitides such as Behçet's disease. Because therapeutic intervention varies greatly in these acute situations, identification of the causative agent is essential. Serology is rarely helpful, whereas analysis of aqueous humor or vitreous samples provides clues to the etiology. Aqueous humor antibody testing and PCR have demonstrated e... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3053349 Wed, 02 Dec 2009 00:00:00 +0100 3053349 [Diagnosis and therapy of acute retinal necrosis.] http://www.medworm.com/index.php?rid=3053348&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19949952%26dopt%3DAbstract Authors: Hillenkamp J PMID: 19949952 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3053348 Wed, 02 Dec 2009 00:00:00 +0100 3053348 [Glaucoma drainage devices.] http://www.medworm.com/index.php?rid=3036084&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19940993%26dopt%3DAbstract This article gives an overview of the current principles, indications, methods, and possible complications of implantation. PMID: 19940993 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=3036084 Fri, 27 Nov 2009 00:00:00 +0100 3036084 [Postoperative complications and management of filtration surgery.] http://www.medworm.com/index.php?rid=2989696&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19908048%26dopt%3DAbstract Authors: Jonescu-Cuypers CP, Seitz B Of the filtering procedures employed, trabeculectomy is the one most frequently used for surgical therapy in primary open angle glaucoma patients. Intra- and postoperative complications must be detected promptly and treated adequately. Many complications arise within the first weeks, such as bleb scaring, decreased flow beneath the scleral flap, extensive filtration with choroidal detachment and anterior chamber narrowing. Fibrin reaction, corneal dellen, iris prolapse, conjunctival leakage and ciliary body detachment are seen more rarely. With prophylactic pre- and perioperative application of antibiotics, wound infections are rare and the risk of endophthalmitis following trabeculectomy remains small. Careful surgical planning requires special con... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2989696 Wed, 11 Nov 2009 00:00:00 +0100 2989696 [Effectiveness and relevance of laser trabeculoplasty : Treatment of open-angle glaucoma.] http://www.medworm.com/index.php?rid=2916566&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19844721%26dopt%3DAbstract Authors: Eckert S Laser trabeculoplasty is a common glaucoma therapy that is safe and effective for reducing intraocular pressure. It was developed as a treatment for open-angle glaucoma in the 1970s, and larger studies proved its effectiveness in the years that followed. In recent years, through the implementation of newer processes such as selective laser trabeculoplasty, laser trabeculoplasty has experienced further developments. Because it causes less damage to the trabecular meshwork, it should have fewer adverse effects, making it a repeatable treatment. Studies on the indications, contraindications, and effectiveness of this method in lowering intraocular pressure are reviewed. PMID: 19844721 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2916566 Wed, 21 Oct 2009 23:00:00 +0100 2916566 [Laser trabeculoplasty: therapeutic options and adverse effects.] http://www.medworm.com/index.php?rid=2916565&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19844722%26dopt%3DAbstract Authors: Wacker T, Eckert S Laser trabeculoplasty is a simple method for treating glaucoma and ocular hypertension and has few adverse effects. There are different laser systems for reducing the intraocular pressure of patients with glaucoma and ocular hypertension. Complications include transient intraocular pressure elevation, iritis, and anterior synechiae. PMID: 19844722 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2916565 Wed, 21 Oct 2009 23:00:00 +0100 2916565 [Available laser systems and mechanism of action in laser trabeculoplasty.] http://www.medworm.com/index.php?rid=2916564&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19844723%26dopt%3DAbstract This article presents the currently most popular laser systems. These various laser procedures are based on the physical structure of the different lasers and on variable generation of laser light. They vary in their effect on the trabecular meshwork on a histopathological level, as well as in the active principles of intraocular pressure reduction. The mechanical, biological, and repopulation theories are currently used to explain the intraocular pressure-lowering effect of the different laser systems; these are discussed in detail. PMID: 19844723 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2916564 Wed, 21 Oct 2009 23:00:00 +0100 2916564 [Volume calculations for current intravitreal injections of Lucentis(R).] http://www.medworm.com/index.php?rid=2909130&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19838710%26dopt%3DAbstract CONCLUSIONS: The original aliquots of Lucentis(R) contain a full volume of 0.23 ml and are not suitable to be used to treat two patients. The volume can only be divided among several patients if several original aliquots are pooled and refilled. This however, presupposes a renewed filling of aliquots which represents a new potential source of contamination. Also legal aspects and the question of stability of the active ingredient have not been taken into consideration. PMID: 19838710 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2909130 Sat, 17 Oct 2009 23:00:00 +0100 2909130 [Acute retinal necrosis from the virologist's perspective.] http://www.medworm.com/index.php?rid=2909129&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19838711%26dopt%3DAbstract Authors: Rautenberg P, Grančičova L, Hillenkamp J, Nölle B, Roider JB, Fickenscher H Acute retinal necrosis occurs in approximately one per million persons per year and is caused in approximately 70% of the cases by the varicella zoster virus or in about 30% of the cases by herpes simplex virus. The early diagnosis is primarily based on virus-specific polymerase chain reaction in fluid from the anterior chamber or vitreous humor and can be supported by the determination of specific antibody titers from fluid and serum. Virus detection provides the basis for early causative therapy which limits disease progression and risk of complications. Retinal infections by varicella zoster virus or herpes simplex virus are treated with aciclovir, ganciclovir, or famciclovir. Ganci... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2909129 Sat, 17 Oct 2009 23:00:00 +0100 2909129 [Biometry in cataract camps : Experiences from north Kenya.] http://www.medworm.com/index.php?rid=2909128&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19838712%26dopt%3DAbstract CONCLUSION: Biometry is a challenging procedure in remote areas where comorbidities are common. However, without biometry and implantation of different IOL powers poor refractive outcome can be expected in around 20% of patients. PMID: 19838712 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2909128 Sat, 17 Oct 2009 23:00:00 +0100 2909128 [Acute retinal necrosis : Clinical features and therapy options.] http://www.medworm.com/index.php?rid=2883572&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19820950%26dopt%3DAbstract Authors: Hillenkamp J, Nölle B, Rautenberg P, Fickenscher H, Roider J Varicella zoster virus is the most frequent cause of acute retinal necrosis (ARN) followed by herpes simplex virus. Retinal ischemia and optic nerve atrophy are the main causes of the frequently poor final visual outcome in severe cases of ARN. The clinical diagnosis of ARN should be made as early as possible. Acyclovir should be administered intravenously due to its unreliable oral bioavailability. Systemic corticosteroids should be applied to suppress tissue damage caused by the host's inflammatory response. Severe cases of ARN should be treated by early vitrectomy with diagnostic vitreous biopsy, intravitreal aciclovir lavage, intraoperative laser retinopexy and silicone oil tamponade. The role of prophylacti... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2883572 Sat, 10 Oct 2009 23:00:00 +0100 2883572 [Tears from a medical historical perspective.] http://www.medworm.com/index.php?rid=2876510&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19809823%26dopt%3DAbstract Authors: Gloor B PMID: 19809823 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2876510 Wed, 07 Oct 2009 23:00:00 +0100 2876510 [Dry eye and sex hormones : Part 1.] http://www.medworm.com/index.php?rid=2876509&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19809824%26dopt%3DAbstract Authors: Schirra F PMID: 19809824 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2876509 Wed, 07 Oct 2009 23:00:00 +0100 2876509 [Albumin eye drops for treatment of ocular surface diseases.] http://www.medworm.com/index.php?rid=2876508&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19813016%26dopt%3DAbstract Authors: Unterlauft JD, Kohlhaas M, Hofbauer I, Kasper K, Geerling G For more than 10 years eye drops made from autologous serum have become an established therapy to support corneal wound healing in ocular surface diseases, such as persistent epithelial defects and dry eye. Serum eye drops can only be dispensed by institutions which have obtained a specific license from the appropriate local authorities and this applies to only a few institutes in Germany. The main protein component of serum is albumin which is commercially available as a quality controlled medical product from the pharmaceutical industry and could thus be used as an alternative to autologous serum eye drops. The wound healing effect of albumin eye drops has already been demonstrated in vitro. Here we outline the ther... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2876508 Wed, 07 Oct 2009 23:00:00 +0100 2876508 [Descemet's stripping automated endothelial keratoplasty (DSAEK).] http://www.medworm.com/index.php?rid=2857865&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19798505%26dopt%3DAbstract Authors: Cursiefen C, Kruse FE, Penetrating keratoplasty has been the gold standard for the surgical treatment of corneal endothelial pathologies, but tremendous progress has been made in recent years in improving the technology of posterior lamellar keratoplasty techniques such as Descemet's stripping automated endothelial keratoplasty (DSAEK). This progress is shown by a literature review using PubMed sources and our own clinical and experimental data. Posterior lamellar keratoplasty using a microkeratome is a reliable surgical technique for Fuchs' endothelial dystrophy and pseudophakic bullous keratopathy. Visual rehabilitation is faster with lamellar compared with penetrating keratoplasty, but final visual acuity seems to be a bit reduced. Posterior lamellar keratoplasty technique... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2857865 Fri, 02 Oct 2009 23:00:00 +0100 2857865 [Morphology of macular holes after pars plana vitrectomy with silicone oil endotamponade : A pilot study with high resolution Fourier domain OCT (Cirrus OCT).] http://www.medworm.com/index.php?rid=2852580&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19787354%26dopt%3DAbstract CONCLUSIONS: This pilot study showed that the aspect of macular holes under silicone oil seems to influence the prognosis after oil removal. Thus, silicone oil removal as well as further surgery may be planned. The reliable analysis of macular holes under silicone oil has only become possible with high resolution Fourier domain OCT. PMID: 19787354 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2852580 Tue, 29 Sep 2009 23:00:00 +0100 2852580 [Erythropoietin protects retinal ganglion cells and visual function after ocular ischemia and optic nerve compression.] http://www.medworm.com/index.php?rid=2852579&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19787355%26dopt%3DAbstract CONCLUSION: The combination of toxicological safety and protection of retinal neurons makes EPO a promising drug for ischemic retinal diseases and traumatic optic neuropathy. PMID: 19787355 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2852579 Tue, 29 Sep 2009 23:00:00 +0100 2852579 [A new toric diffractive multifocal lens for refractive surgery.] http://www.medworm.com/index.php?rid=2852578&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19787356%26dopt%3DAbstract CONCLUSIONS: The new toric multifocal lens is a new option in refractive surgery. The first results are very promising but further results and a comparison to the bioptics procedure have to be awaited. PMID: 19787356 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2852578 Tue, 29 Sep 2009 23:00:00 +0100 2852578 [Expression of matrix metalloproteinase-19 in the human cornea : Wound healing in the MMP-19 knock-out mouse model.] http://www.medworm.com/index.php?rid=2833545&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19777244%26dopt%3DAbstract CONCLUSION: MMP-19 showed a strong expression in the basal cells of the human corneal epithelium. Corneal re-epithelialization was slightly faster in the MMP-19 knock-out mouse. No differences in the expression of laminin-5 could be detected. PMID: 19777244 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2833545 Thu, 24 Sep 2009 23:00:00 +0100 2833545 [Erdheim-Chester disease of the orbit with compressive optic neuropathy.] http://www.medworm.com/index.php?rid=2833544&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19777245%26dopt%3DAbstract Authors: Manousaridis HK, Casper J, Schittkowski MP, Nizze H, Guthoff RF A 60-year-old man presented with left exophthalmos and deterioration in visual acuity of slow evolution. Bilateral orbital Erdheim-Chester disease was diagnosed. Systemic evaluation revealed a retroperitoneal fibrosis. Treatment with interferon-alpha followed, but bilateral compressive optic neuropathy with visual acuity deterioration and visual field defects evolved. Bilateral orbital decompression was performed. PMID: 19777245 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2833544 Thu, 24 Sep 2009 23:00:00 +0100 2833544 [Results of 308 consecutive femtosecond laser cuts for LASIK.] http://www.medworm.com/index.php?rid=2833543&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19777246%26dopt%3DAbstract CONCLUSIONS: In this small series of 308 operations, femto-LASIK induced no major cut complications. PMID: 19777246 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2833543 Thu, 24 Sep 2009 23:00:00 +0100 2833543 [Intracameral moxifloxacin: a safe option for endophthalmitis prophylaxis? : In vitro safety profile for intraocular application.] http://www.medworm.com/index.php?rid=2801478&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756636%26dopt%3DAbstract CONCLUSION: Vigamox(R) did not show significant toxicity on primary RPEs, TMCs, LECs, CECs, or human corneal endothelium at concentrations up to 150 microg/ml. The MIC90 of moxifloxacin for pathogens commonly encountered in endophthalmitis is known to be in the range of 0.25-2.5 microg/ml. Therefore, intracameral use of Vigamox(R) at concentrations up to 150 microg/ml may be safe and effective for preventing endophthalmitis after intraocular surgery. PMID: 19756636 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801478 Wed, 16 Sep 2009 23:00:00 +0100 2801478 [Acute angle closure glaucoma with unilateral acute loss of vision.] http://www.medworm.com/index.php?rid=2801479&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756635%26dopt%3DAbstract We report the case of a 31-year-old patient who presented with unilateral acute loss of vision, severe headache, and symptoms of an acute angle-closure glaucoma. Surprisingly, a prepapillary uveal melanoma was the underlying reason; that is, a masquerade syndrome was seen. Enucleation and histopathological investigation of that eye were performed within 3 days after first presentation. Acute angle-closure glaucoma as the initial presentation of uveal melanoma is rare. Nevertheless, clinicians should be aware that patients with refractory unilateral angle-closure glaucoma and asymmetrically opaque media may harbor an occult uveal melanoma. PMID: 19756635 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801479 Tue, 15 Sep 2009 23:00:00 +0100 2801479 [Subluxation of hydrophilic acrylate intraocular lenses due to massive capsular fibrosis.] http://www.medworm.com/index.php?rid=2801477&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756637%26dopt%3DAbstract CONCLUSIONS: The pattern of lens opacification should receive attention when one is choosing an IOL type. Eyes showing pseudoexfoliation syndrome as well as post-uveitis eyes might require a hydrophilic IOL for less cellular reaction, whereas a posterior subcapsular cataract might need a hydrophobic IOL to prevent a massive capsular fibrosis. In the case of increased capsular contraction, unreflected YAG laser capsulotomy may result in IOL subluxation when the lens design cannot handle capsule shrinkage, as demonstrated here. PMID: 19756637 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801477 Tue, 15 Sep 2009 23:00:00 +0100 2801477 [Retrospective case analysis of ophthalmological and systemic risk factors in patients with retinal vascular occlusion.] http://www.medworm.com/index.php?rid=2801475&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756639%26dopt%3DAbstract CONCLUSIONS: TTE and carotid Doppler are important tools in the diagnosis of sources of emboli in patients with CRAO, while for CRVO abnormal findings are revealed by TTE and carotid Doppler less often. Thrombophilia should be ruled out in the absence of common risk factors, especially in younger patients and systemic hypertension should be adequately controlled. PMID: 19756639 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801475 Tue, 15 Sep 2009 23:00:00 +0100 2801475 [Retinal pigment epithelium atrophy and hypacousia in monozygotic twin sisters.] http://www.medworm.com/index.php?rid=2801473&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756641%26dopt%3DAbstract Authors: Oppermann T, Roider J, Hillenkamp J Mitochondrial A3243G point mutations cause variable pathologic changes in different organs. Funduscopy revealed sharply demarcated central areas of atrophy of the retinal pigment epithelium (RPE) which corresponded to the visual field defects. Fundus autofluorescence was reduced in the areas of RPE atrophy but showed granular hyperfluorescence of the adjacent RPE. Heteroplasmic mitochondrial mutations may cause variable changes in different organ systems. However, the ocular phenotype in the described pair of twins was almost identical. Fundus autofluorescence showed little progression of the RPE atrophy. PMID: 19756641 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801473 Tue, 15 Sep 2009 23:00:00 +0100 2801473 [Intensive intracorneal keloid formation in a case of Peters plus syndrome and in Peters anomaly with maximum manifestation.] http://www.medworm.com/index.php?rid=2801472&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756642%26dopt%3DAbstract We present two cases of Peters anomaly (Peters plus syndrome and a maximum manifestation variant) with abnormally thickened cornea and corneal staphyloma. Both patients presented to our hospital shortly after birth and were treated with perforating keratoplasty and lensectomy. Histological analysis showed marked thickening of the corneal stroma due to abnormal stromal connective tissue deposition. Additionally, both eyes showed the characteristic changes of Peters anomaly with corneal opacity, adherence of the iris stroma and anterior lens surface to the posterior corneal surface, absence of the corneal endothelium, Descemet and Bowmans layers. Peters anomaly with abnormally thick intracorneal fibrosis with or without congenital corneal staphyloma is a very rare manifestation. PMID: 19... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801472 Fri, 11 Sep 2009 23:00:00 +0100 2801472 ["Lacteocrumenasia" - Capsular block syndrome III.] http://www.medworm.com/index.php?rid=2801471&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756643%26dopt%3DAbstract Authors: Ramharter-Sereinig A, Schmid E, Bechrakis N Capsular block syndrome (CBS) is a complication of uncomplicated cataract surgery. Depending on etiology and the time of onset CBS can be subdivide into three types. The cases of 4 patients with CBS type III who presented with a milky fluid in the space between the posterior surface of the implanted intraocular lens (IOL) and the anterior surface of the distended posterior capsular bag are described. All patients complained of reduced vision. The therapy of choice is Nd:YAG laser posterior capsulotomy but with suspected low-grade endophthalmitis surgical intervention can also be carried out and submitting the plug for bacterial culture. PMID: 19756643 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801471 Fri, 11 Sep 2009 23:00:00 +0100 2801471 [Acanthamoeba keratitis in patients with contact lens wear in the Department of Ophthalmology in Debrecen.] http://www.medworm.com/index.php?rid=2801470&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756644%26dopt%3DAbstract CONCLUSIONS: Early diagnosis and long-term suitable local therapy are necessary for effective recovery. If the patient wears contact lens and there is severe pain with ring infiltration in the cornea, Acanthamoeba infection should be considered and suitable therapy should be given. Immediately performed perforating keratoplasty does not lead to visual improvement. Prevention by informing the patients about adequate hygiene and use of the cleaning solutions is one of the most important tasks of contact lens specialists. PMID: 19756644 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801470 Fri, 11 Sep 2009 23:00:00 +0100 2801470 [Retained Descemet's membrane after penetrating keratoplasty for macular corneal dystrophy.] http://www.medworm.com/index.php?rid=2801469&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756645%26dopt%3DAbstract Authors: Heindl LM, Cursiefen C A 35-year-old woman underwent excimer laser penetrating keratoplasty for macular corneal dystrophy in the right eye. Two months after surgery, a thin transparent membrane behind the clear corneal graft was noted. Anterior segment optical coherence tomography revealed duplication of the anterior chamber by this membrane, originating from the host cornea without direct contact to the donor tissue. Trypan-blue-assisted descemetorhexis was performed, and histopathology confirmed the diagnosis of retained Descemet's membrane. Four months later, the graft was clear with good visual acuity and no sign of retrocorneal membrane. PMID: 19756645 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801469 Fri, 11 Sep 2009 23:00:00 +0100 2801469 [Continuous intraocular pressure measurement : First results with a pressure-sensitive contact lens.] http://www.medworm.com/index.php?rid=2801468&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756646%26dopt%3DAbstract CONCLUSIONS: CL-DCT allows non-invasive and continuous measurements of IOP. The measured values are comparable to the expected ones. Further studies are necessary to compare the measurement accuracy of CL-DCT with that of slit lamp adapted DCT (SL-DCT). PMID: 19756646 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801468 Fri, 11 Sep 2009 23:00:00 +0100 2801468 [Unilateral occlusion of the retinal artery branch and retinal white dots.] http://www.medworm.com/index.php?rid=2801474&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756640%26dopt%3DAbstract CONCLUSIONS: Because of the increasing incidence of syphilis it is becoming more important to consider this disease in the differential diagnosis not only for unclear symptom complexes but also in apparently obvious situations. PMID: 19756640 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801474 Tue, 08 Sep 2009 23:00:00 +0100 2801474 [Hereditary optic atrophies.] http://www.medworm.com/index.php?rid=2801476&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19756638%26dopt%3DAbstract Authors: Poloschek CM, Lagrèze WA Hereditary optic neuropathies are caused by mutations either in the nuclear or mitochondrial genome and lead to retinal ganglion cell death mediated by reduced oxidative phosphorylation, fragmentation of the mitochondrial network, and increased sensitivity to apoptosis. Nuclear mutations result in autosomal dominant optic atrophy, autosomal recessive optic atrophy, or X-linked recessive optic atrophy, whereas mitochondrial mutations result in Leber's hereditary optic neuropathy, which is maternally inherited. A tentative diagnosis of a hereditary optic neuropathy can usually be made on the grounds of a thorough patient and family history, visual field and color vision tests, and a detailed assessment of the optic nerve head. The rarity of heredita... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2801476 Sat, 05 Sep 2009 23:00:00 +0100 2801476 [Possibilities and limitations of telemedicine in general practitioner practices.] http://www.medworm.com/index.php?rid=2769285&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19730867%26dopt%3DAbstract Authors: van den Berg N, Meinke C, Hoffmann W According to the AGnES concept (general-practitioner-supporting, community-based, e-health-assisted systemic intervention), general practitioners (GPs) can delegate certain components of medical care in the context of home visits by qualified AGnES employees. Within the framework of six AGnES projects, different telemedical applications have been implemented. Telemedical monitoring of patients was implemented to analyse the feasibility and acceptance within GP practices. One hundred sixty-two patients used a telemedical monitoring system (e.g. scale/sphygmomanometer and intraocular pressure measurement system). Regarding communication in cases of acutely necessary GP consultations, telephone calls and videoconferences between the GP and the... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2769285 Thu, 03 Sep 2009 23:00:00 +0100 2769285 [Pareto optimal communication of the medical qualities of practicing ophthalmologists : A new option for patient information?] http://www.medworm.com/index.php?rid=2723232&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19697042%26dopt%3DAbstract CONCLUSION: At least in the near future there will be no new Pareto optimal information systems available for patients in order to find the appropriate ophthalmologist. In the mid-term the situation could change if the open questions can be resolved. PMID: 19697042 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2723232 Fri, 21 Aug 2009 23:00:00 +0100 2723232 [Technical options and prospects for telemedical devices in ophthalmology.] http://www.medworm.com/index.php?rid=2723234&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19693510%26dopt%3DAbstract Authors: Großjohann R, Jürgens C, Tost F Home monitoring will soon be established as an innovative way to provide telemedical care in ophthalmology. At present there are no fundamental technical restrictions for telemedical enhancements in ophthalmology, however a wider application range and depth could lead to harmonized and simplified device and interface development. This may help to initiate new concepts in ophthalmological home monitoring. PMID: 19693510 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2723234 Thu, 20 Aug 2009 23:00:00 +0100 2723234 [Possibilities and limitations of telemedical home monitoring in ophthalmology.] http://www.medworm.com/index.php?rid=2723233&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19693511%26dopt%3DAbstract Authors: Jürgens C, Großjohann R, Tost F For medical professionals, home monitoring represents an innovative health service for remote patient care: The patient may remain in his or her domestic environment and continue normal activities. The physician can also, through technical and organizational integration, provide medical attendance from his or her usual working environment. All in all, in the near future home monitoring can help provide sufficient health services while also enabling medical resources to be used more effectively. The patient may benefit from individually optimized treatment and active integration into medical care. The better we manage the technical, organizational, medical, legal, and economic challenges of telemedicine, the better we can minimize the l... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2723233 Thu, 20 Aug 2009 23:00:00 +0100 2723233 [Data security and the handling of patient data in home monitoring systems.] http://www.medworm.com/index.php?rid=2704292&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19680662%26dopt%3DAbstract Authors: Heydenreich F, Jürgens C, Tost F Data security must be considered seriously in the context of telemedical home monitoring because of the transmission and communication of patients' personal data. The contract governing medical treatment allows the ophthalmologist to process all data relevant to treatment. In Germany the legal framework for this purpose is provided by the Data Protection Act, various German hospital acts, and codes of medical professional conduct. In principle, these rules apply to telemedical home monitoring as well as to common physician-patient relationships. The patient must be informed extensively in an understandable manner and must give his or her written consent. However, the advanced options of new IT technologies demand the development of technic... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2704292 Thu, 13 Aug 2009 23:00:00 +0100 2704292 [Waldenstrom's macroglobulinaemia of the lacrimal gland in a patient with sarcoidosis.] http://www.medworm.com/index.php?rid=2695754&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19669149%26dopt%3DAbstract We report a case of bilateral lacrimal gland involvement as the first sign of Waldenstrom's macroglobulinaemia in a patient with sarcoidosis. Histological analysis of an incisional biopsy revealed a lymphoplasmocytic lymphoma consistent with Waldenstrom's macroglobulinaemia. No noncaseating granulomas were encountered. Systemic treatment was initiated and resulted in complete resolution of the lesions. In a patient with a systemic disease, such as sarcoidosis, and lacrimal gland involvement, a biopsy of the lacrimal gland mass should be taken to make a correct diagnosis and start appropriate treatment. PMID: 19669149 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2695754 Sat, 08 Aug 2009 23:00:00 +0100 2695754 [Combined intravitreal injection of bevacizumab and SF(6) gas for treatment of submacular hemorrhage secondary to age-related macular degeneration.] http://www.medworm.com/index.php?rid=2695753&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19669150%26dopt%3DAbstract CONCLUSIONS: Our findings suggest that combined intravitreous injections of bevacizumab and SF(6) have the potential to improve visual outcome in patients with subretinal hemorrhage secondary to ARMD. However, further treatment of the underlying choroidal neovascularization is mandatory. PMID: 19669150 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2695753 Sat, 08 Aug 2009 23:00:00 +0100 2695753 [Glaucoma diagnosis and follow-up using the Heidelberg Retina Tomograph.] http://www.medworm.com/index.php?rid=2684148&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19662420%26dopt%3DAbstract Authors: Hoffmann EM, Lamparter J, Schmidt T, Schulze A The Heidelberg Retina Tomograph (HRT) is a glaucoma diagnosis system that provides fast, noninvasive topographic information about the optic nerve head, the neuroretinal rim, and the thickness of the nerve fiber layer. With these capabilities, it is one of the leading laser systems for detecting glaucoma. Statistical methods such as the Moorfields regression analysis and the glaucoma probability score, as well as discriminant functions implemented in the instrument, support the clinician in discriminating between glaucoma and healthy eyes. The primary method for assessing glaucomatous change using the HRT is topographic change analysis, a technique that compares the variability within a baseline examination to that between baselin... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2684148 Fri, 07 Aug 2009 23:00:00 +0100 2684148 [Optic disc photography and retinal nerve fiber layer photography.] http://www.medworm.com/index.php?rid=2684147&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19662421%26dopt%3DAbstract Authors: Hoffmann EM In addition to optic disc assessment at the slit lamp and the use of imaging devices for glaucoma diagnosis, optic disc photography is widely used in clinical practice. The advantages of stereophotography are a permanent recording of the optic disc status especially used for serial evaluation of discs, good visibility of the peripapillary region and a relatively fast examination without pupil dilation (if using non-mydriatic fundus cameras). The limitations are the need for clear media, pupil dilation, a skilled photographer and the delay involved.Retinal nerve fiber layer (RNFL) photography is based on the absorption of green light by melanin in the retinal nerve fiber layer. In comparison to scanning laser devices this methodology is not as convenient and require... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2684147 Fri, 07 Aug 2009 23:00:00 +0100 2684147 [Scanning electron microscopic characteristics of lamellar keratotomies using the Femtec femtosecond laser and the Zyoptix XP microkeratome : A comparison of quality.] http://www.medworm.com/index.php?rid=2679368&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657659%26dopt%3DAbstract CONCLUSIONS: A comparison of the two systems shows that the microkeratome creates a more homogenous cut surface. The need for preparation after automated cutting with the femtosecond laser leads to irregularities on the cut surface. The cut edges of both systems tested here differ concerning their angles on entering the tissue. With regard to the sharpness of the cuts, the qualitative aspect is nearly similar, although the cut edges of the microkeratome are serrated. Because the microkeratome-cut edge has a flatter course, the wound area might be bigger. Cut edges with the steepness produced by the femtosecond laser could be an advantage for repositioning the flap after LASIK. If excimer laser ablation is performed later, the flap bed created by the femtosecond laser could be disadvantageo... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2679368 Thu, 06 Aug 2009 23:00:00 +0100 2679368 [Anemia as the cause of bilateral papilledema.] http://www.medworm.com/index.php?rid=2679367&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19657660%26dopt%3DAbstract Authors: Wirtz N, Biester S, Weckerle P, Lüke M The case of a 41-year-old male patient is described who presented with progressive deterioration of vision in both eyes. The results of laboratory tests and magnetic resonance tomography led to the suspicion of a plasmacytoma, which was confirmed by serum electrophoresis. Treatment with two cycles of vincristine, adriamycine and dexamethasone led to a regression of the papilledema and remission of the system disease. PMID: 19657660 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2679367 Thu, 06 Aug 2009 23:00:00 +0100 2679367 [Bilateral panuveitis with papillary swelling.] http://www.medworm.com/index.php?rid=2679369&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19655150%26dopt%3DAbstract Authors: Pietzsch M, Kutschan A, Hager A, Wiegand W Lues (syphilis) is a chronic cyclic infectious disease which can continue for decades if untreated. A simultaneous HIV infection can result in false negative results in serological tests for lues. The occurrence of neurolues has frequently been described in HIV positive patients. In the differential diagnosis an early ocular manifestion of lues should be considered. A 40-year-old homosexual patient presented in our hospital with bilateral pain-free increasing loss of vision. The ophthalmological examination revealed an intermediately expressed panuveitis with streaky opacity of the vitreous body and pronounced bilateral papillary swelling. Following systemic anti-inflammatory therapy with cortisone the situation worsened after initial... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2679369 Wed, 05 Aug 2009 23:00:00 +0100 2679369 [New options of high resolution optical coherence tomography in glaucoma diagnostic.] http://www.medworm.com/index.php?rid=2672332&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19652978%26dopt%3DAbstract Authors: Schulze A, Lamparter J, Hoffmann EM At present time domain optical coherence tomography (TD-OCT) plays a less important role in glaucoma diagnostics and is used mainly for macula diagnostics. The Fourier domain optical coherence tomography (FD-OCT) with enhanced resolution has new options to detect glaucoma changes. This new technology is referred as frequency domain or spectral domain OCT. This paper will present current and new options of OCT in glaucoma diagnostics. Measurements of the optic nerve head and the retinal nerve fiber layer thickness using this new technology have been shown to be reproducible. Devices which use TD-OCT (e.g. Stratus-OCT) have a lower resolution than devices that use FD-OCT (e.g. RTVue-100; 10 microm versus 5 microm axial resolution). A new optio... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2672332 Tue, 04 Aug 2009 23:00:00 +0100 2672332 [Measuring intraocular pressure by different methods.] http://www.medworm.com/index.php?rid=2672331&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19652979%26dopt%3DAbstract This article describes the individual methods of measurement and discusses their advantages and disadvantages. PMID: 19652979 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2672331 Tue, 04 Aug 2009 23:00:00 +0100 2672331 [Frequency-doubling technology : A new method for determining glaucomatous visual field defects.] http://www.medworm.com/index.php?rid=2672330&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19652980%26dopt%3DAbstract Authors: Lamparter J, Schulze A, Hoffmann EM Glaucoma is a disease in which death of retinal ganglion cells is associated with loss of visual function. The gold standard for visual field testing has been standard automated perimetry (SAP). However, up to 30-50% of retinal ganglion cells must be lost before a scotoma is detected with SAP. Therefore, investigators have been interested in finding diagnostic techniques that would allow earlier detection of visual field loss than that detected by standard white-on-white perimetry. Frequency-doubling technology (FDT) has been suggested as a promising technique that may detect glaucomatous ganglion cell damage earlier than SAP by targeting a sparsely spaced subsystem of Mgamma retinal ganglion cells where cell damage is less masked by redunda... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2672330 Tue, 04 Aug 2009 23:00:00 +0100 2672330 [Glaucoma diagnosis using scanning laser polarimetry.] http://www.medworm.com/index.php?rid=2672329&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19652981%26dopt%3DAbstract Authors: Hoffmann EM, Schulze A Scanning laser polarimetry (SLP) is another technology for early glaucoma diagnosis. This technique (represented in the GDx from Carl Zeiss Meditec, Jena, Germany) is based on polarimetry and measures the retinal nerve fiber layer (RNFL) thickness. Compared with previous instruments without customized corneal compensation, the variable corneal compensation technology enables improved differentiation between glaucoma and healthy eyes. Limitations are the atypical birefringence patterns that exist in some eyes, showing false high RNFL values. The newest software uses enhanced corneal compensation (ECC) technology to avoid these atypical patterns and to improve glaucoma diagnosis. Advantages of SLP include independence from drawing a contour line and a refe... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2672329 Tue, 04 Aug 2009 23:00:00 +0100 2672329 [Retinal detachment in pediatrics : Etiology and risk factors.] http://www.medworm.com/index.php?rid=2614255&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19609777%26dopt%3DAbstract CONCLUSIONS: The study confirms ocular trauma and myopia as important risk factors for juvenile retinal detachment. Because of the high association with malformations as an endogenous background and their conspicuous frequency in patients with bilateral retinal detachment, a genetic background for retinal detachment may be concluded. PMID: 19609777 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2614255 Fri, 17 Jul 2009 23:00:00 +0100 2614255 http://www.medworm.com/index.php?rid=2614254&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19609778%26dopt%3DAbstract Ophthalmologe. 2009 Jul 18; Authors: Hoffmann EM PMID: 19609778 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2614254 Fri, 17 Jul 2009 23:00:00 +0100 2614254 [Evaluation of an Internet-based e-learning ophthalmology module for medical students.] http://www.medworm.com/index.php?rid=2614253&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19609779%26dopt%3DAbstract CONCLUSION: E-learning represents a sensible addendum to the established ophthalmology training for medical students. It is comparably easy to integrate into the curriculum and is well accepted by medical students. PMID: 19609779 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2614253 Fri, 17 Jul 2009 23:00:00 +0100 2614253 [Volume overload from hydrogel expander after treatment for enophthalmos.] http://www.medworm.com/index.php?rid=2606832&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19597823%26dopt%3DAbstract Authors: Küstner M, Riebeling P, Podmelle F, Kaduk W, Tost F In the subject of this case report, a self-inflating hydrogel expander was implanted as a treatment for posttraumatic enophthalmos in a fully sighted eye. The intervention caused hypertropia with diplopia, restriction of eye movements, visual field defects, and colour desaturation as a result of excessive swelling of the expander. Once the expander volume was adjusted, clinical signs regressed, and the aesthetic results were excellent. Following the implantation of self-inflating orbit expanders, it is advisable to carry out immediate follow-up during the expander's swelling period, and long-term follow-up is also advised to rule out late sequelae, as a position-dependent secondary glaucoma could occur. PMID: 1959782... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2606832 Tue, 14 Jul 2009 23:00:00 +0100 2606832 [A stochastic test for validity control of visual acuity statements.] http://www.medworm.com/index.php?rid=2606831&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19597824%26dopt%3DAbstract CONCLUSION: This convenient test is a practical tool both for regular determination of visual acuity and for detection of false statements by means of an atypical psychometric function. It also allows for application of further validity checks. Intentionally false statements can be influenced by misleading calibration values. PMID: 19597824 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2606831 Tue, 14 Jul 2009 23:00:00 +0100 2606831 [Intermittent elevation deficiency.] http://www.medworm.com/index.php?rid=2599062&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19593572%26dopt%3DAbstract Authors: van Waveren M, Jägle H A 7-year-old boy presented with vertical double images. A paediatric examination and magnetic resonance imaging of the head did not show any pathological findings. The diagnosis was an acquired click syndrome of the superior oblique muscle. In cases with inflammatory and systemic origin the underlying disease should be treated. Local steroid therapy can be carried out for improvement of inflammation in the region of the superior oblique muscle with a high degree of suffering. PMID: 19593572 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2599062 Sat, 11 Jul 2009 23:00:00 +0100 2599062 [Can HRT be a useful tool in differentiating lamellar macular holes from full-thickness macular holes?] http://www.medworm.com/index.php?rid=2589261&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19588155%26dopt%3DAbstract CONCLUSION: The HRT 3 macular module enables diagnosis of macular holes. Full-thickness macular holes could be differentiated from non-full-thickness macular holes; however, lamellar macular holes could not be differentiated from macular pseudoholes. PMID: 19588155 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2589261 Thu, 09 Jul 2009 23:00:00 +0100 2589261 [Comparison of parameters of time-resolved autofluorescence between healthy subjects and patients suffering from early AMD.] http://www.medworm.com/index.php?rid=2589260&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19588156%26dopt%3DAbstract CONCLUSION: Measurements in the 30 degrees fundus field demonstrated that specific alterations were already present even in early AMD and also outside the macula. These act in the neuronal retina, because parameter tau2 is related to this layer. Increases in the lifetime of parameter tau2 in the short wave channel could at least partially be determined by an increase of protein bound NADH, the content of which increases with reduced cellular respiration. PMID: 19588156 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2589260 Thu, 09 Jul 2009 23:00:00 +0100 2589260 [Scanpath of experienced and inexperienced drivers in motor sports.] http://www.medworm.com/index.php?rid=2589259&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19588157%26dopt%3DAbstract CONCLUSION: The results point to a learned scan path for the ED. Consequently, we were able to show an ideal scan path that emphasises a learning process for the ID. PMID: 19588157 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2589259 Thu, 09 Jul 2009 23:00:00 +0100 2589259 [Unclear deterioration of vison after renal transplant.] http://www.medworm.com/index.php?rid=2584455&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19585124%26dopt%3DAbstract Authors: Hild M, Walter HS, Milioti G, Seitz B A 27-year-old female patient reported a variable but unsatisfactory visual acuity which had persisted for several years. The patient had been dependent on dialysis from the age of 14 years old and from then on also needed a hearing aid. A kidney had been transplanted 5 years ago. The diagnosis was anterior lenticonus due to Alport syndrome. PMID: 19585124 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2584455 Wed, 08 Jul 2009 23:00:00 +0100 2584455 [Anterior surface breakdown following evisceration : "Classic", "scleral modification", and "scleral patch techniques"] http://www.medworm.com/index.php?rid=2577133&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19578857%26dopt%3DAbstract CONCLUSION: Compared with the scleral modification and scleral patch techniques, conjunctival breakdown and implant extrusion were seen more frequently after classic evisceration with implant placement. Implant size or indication for surgery were not related to the frequency of these complications. PMID: 19578857 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2577133 Sat, 04 Jul 2009 23:00:00 +0100 2577133 http://www.medworm.com/index.php?rid=2571606&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19575204%26dopt%3DAbstract Ophthalmologe. 2009 Jul 4; Authors: PMID: 19575204 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2571606 Fri, 03 Jul 2009 23:00:00 +0100 2571606 [Tears from an art historical point of view.] http://www.medworm.com/index.php?rid=2571605&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19575205%26dopt%3DAbstract Authors: Spiekermann G Drawing on works of literature, philosophy and art the author tries to unearthen the multiple meanings of tears and crying in the history of the fine arts. The essay spans from pictures of the earliest known representations of tears in the Middle Ages to the tears found in photographies of the Modern Arts of nowadays. PMID: 19575205 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2571605 Fri, 03 Jul 2009 23:00:00 +0100 2571605 [Neovascular age-related macular degeneration under anti-angiogenic therapy : Subretinal fluid is a relevant prognostic parameter.] http://www.medworm.com/index.php?rid=2571604&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19575206%26dopt%3DAbstract CONCLUSION: Data show that some retinal thickness values correlated to VA in the spectral domain OCT but not in Stratus OCT. In this study VA at baseline and the SRFV were the most important prognostic factors for VA at 3 months.. This demonstrates the important role of SRFV measurements as a relevant prognostic factor in nAMD and encourages more research into the analysis of OCT parameters in order to have a better understanding of the prognosis of individual patients receiving anti-angiogenic therapy for nAMD. PMID: 19575206 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2571604 Fri, 03 Jul 2009 23:00:00 +0100 2571604 [Vascular lesion of the conjunctiva.] http://www.medworm.com/index.php?rid=2537703&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19557417%26dopt%3DAbstract Authors: Baumüller S, Kosanetzky N, Charbel Issa P, Holz FG, Löffler KU A 44-year-old male patient first noticed a pain-free light red swelling of the right eye in 1983. Based on the results of the early indocyanine green angiography, MRI and sonography, a racemose hemangioma of the conjunctiva was diagnosed. Although a racemose hemangioma already exists at birth, it remains clinically silent for a long time and symptoms often first appear in early adulthood. In this patient external surgical excision was terminated due to substantial bleeding. A symptomatic treatment in the sense of surface care is considered to be the best option. PMID: 19557417 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537703 Fri, 26 Jun 2009 23:00:00 +0100 2537703 [Keratoplasty: laminate or penetrate? : Part 2: Lamellar keratoplasty.] http://www.medworm.com/index.php?rid=2537707&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19543736%26dopt%3DAbstract Authors: Maier P, Reinhard T A number of corneal disorders sooner or later call for a decision as to whether corneal grafting is necessary. In contrast to the current gold standard, penetrating keratoplasty (PKP), former lamellar techniques had the disadvantage of worse visual outcomes due to interface problems. A number of recent new technical developments have led to a 'renaissance' of various lamellar keratoplasty methods. Deep anterior lamellar keratoplasty (DALK) avoids the risk of endothelial immune reactions. However, visual ourcomes are comparable to PKP only is complete baring of Descemet's membrane is achieved. In Descemet stripping (automated) endothelial keratoplasty [DS(A)EK], a variation of posterior lamellar keratoplasty, only the diseased endothelium is removed with the... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537707 Fri, 19 Jun 2009 23:00:00 +0100 2537707 [Correction factors for central corneal thickness in Goldmann applanation tonometry.] http://www.medworm.com/index.php?rid=2537713&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19506886%26dopt%3DAbstract CONCLUSIONS: Measurement of CCT is valuable for prognostic assessment of glaucoma, but not for correction factors for corneal thickness. PMID: 19506886 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537713 Tue, 09 Jun 2009 23:00:00 +0100 2537713 [Circumscribed retinal detachment after radial optic neurotomy for central retinal vein occlusion.] http://www.medworm.com/index.php?rid=2537729&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19499226%26dopt%3DAbstract CONCLUSIONS: Although other mechanisms should be taken into account, this case indicates that it might be possible to create a fistula between the subarachnoid and subretinal space, leading to a slowly developing retinal detachment. A similar case report pointed out that special attention should be paid to the depth of the radial incision into the optic nerve head. PMID: 19499226 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537729 Fri, 05 Jun 2009 23:00:00 +0100 2537729 [Arthrogryposis multiplex congenita and retinitis pigmentosa.] http://www.medworm.com/index.php?rid=2537727&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19499227%26dopt%3DAbstract CONCLUSION: This young female demonstrated an AMC in combination with retinitis pigmentosa, but other disease manifestations or cerebral retardation could not be found. We present here an unusual case of what seems to be a new athrogryposis syndrome. PMID: 19499227 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537727 Fri, 05 Jun 2009 23:00:00 +0100 2537727 [Treatment of chronic blepharokeratoconjunctivitis with local calcineurin inhibitors.] http://www.medworm.com/index.php?rid=2537725&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19499228%26dopt%3DAbstract Authors: Auw-Hädrich C, Reinhard T Topical calcineurin inhibitors (cyclosporin A 1%, FK506, pimecrolimus) can be useful for treating chronic blepharokeratoconjunctivitis in addition to lid hygiene and lubricants. This treatment leads to an improvement of dry eye symptoms and reduces inflammation. PMID: 19499228 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537725 Fri, 05 Jun 2009 23:00:00 +0100 2537725 [In vivo imaging of retinal cell apoptosis following acute light exposure.] http://www.medworm.com/index.php?rid=2537723&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19499229%26dopt%3DAbstract This study investigated whether in vivo detection with DARC (detection of apoptosing retinal cells) technology could identify cells undergoing apoptosis. METHODS: Acute blue light damage (lambda=405 nm; 3.2 mW/cm(2)) was applied to eyes of dark Agouti rats over 2 h. In vivo retinal imaging using confocal scanning laser ophthalmoscopy was performed before and directly after light exposure as well as after 24 h of dark adaptation. Development of retinal cell apoptosis was then assessed using intravitreal fluorescent-labeled annexin-5 with DARC technology in vivo. RESULTS: Directly after light exposure, no pathological retinal changes were observed by in vivo imaging. However, retinal flattening and the development of apoptosis within the irradiated retina occurred 1 day later and following d... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537723 Fri, 05 Jun 2009 23:00:00 +0100 2537723 http://www.medworm.com/index.php?rid=2537721&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19499230%26dopt%3DAbstract CONCLUSION: Both UV-filtering and blue light-absorbing IOLs reduce light-induced RPE damage. The blue light-absorbing IOL further reduced damage compared to the conventional IOL, which supports the hypothesis of possibly also preventing retinal damage in clinical use. PMID: 19499230 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537721 Fri, 05 Jun 2009 23:00:00 +0100 2537721 [Time domain OCT versus frequency domain OCT : Measuring differences of macular thickness in healthy subjects.] http://www.medworm.com/index.php?rid=2537719&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19499231%26dopt%3DAbstract Authors: Chaber S, Helbig H, Gamulescu M BACKGROUND: When changing from previously used time domain OCTs (TD-OCT) to frequency domain OCTs (FD-OCT) the question arises how to evaluate the progress of macular disease. METHODS: OCT examinations and calculation (mapping) of the central retinal thickness were carried out in 40 healthy eyes with the Stratus OCT(R) (Carl Zeiss Meditec Inc.; TD-OCT) as well as the Spectralis-OCT(R) (Heidelberg Engineering GmbH 2008; FD-OCT). RESULTS: The average central macular thickness was 218 microm in the Stratus OCT(R) and 282 microm in the Spectralis-OCT(R). The average difference was 69 microm (p < 0.001). The mean value of single measurements showed a macular thickness of 195 microm when performed with the Stratus OCT(R) and of 235 microm with the ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537719 Fri, 05 Jun 2009 23:00:00 +0100 2537719 [Delayed loss of vision after hammer and chisel injury.] http://www.medworm.com/index.php?rid=2537715&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19504111%26dopt%3DAbstract Authors: Schnaidt AG, Schröder AC, Gatzioufas Z, Löw U, Lang HM, Seitz B Eye injuries caused by foreign bodies are a common diagnosis in many patients with an ocular emergency. A high percentage of foreign bodies are located in the cornea and are easily removed, but an intralenticular foreign body after eye injury is very rare. A 28-year-old man referred to our department with increasing loss of vision in the right eye 1 month after an accident with a hammer and chisel. At the time of admission the patient complained of a significant loss of vision and a traumatic cataract was diagnosed. The examination showed a deep stromal corneal scar and an anterior subcapsular cataract with posterior contusional rosette. Slit-lamp examination in mydriasis aroused the suspicion of an intr... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537715 Fri, 05 Jun 2009 23:00:00 +0100 2537715 [Bilateral recurrent retinal thrombosis in a young man.] http://www.medworm.com/index.php?rid=2537733&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19495773%26dopt%3DAbstract Authors: Harder J, Thürmel K, Maier M, Lanzl I A 41-year-old male patient presented with veiled vision which had appeared only a few hours previously. Funduscopy revealed a retinal edema due to venous stasis retinopathy. A previous history was unknown except for an uncorrected arterial hypertension. A retinal vein thrombosis and macula edema developed in the affected eye. An antiphospholipid antibody syndrome was diagnosed which was treated with anticoagulants. PMID: 19495773 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537733 Thu, 04 Jun 2009 23:00:00 +0100 2537733 [23-gauge-lentectomy for the treatment of congenital cataract.] http://www.medworm.com/index.php?rid=2537711&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19513723%26dopt%3DAbstract CONCLUSION: The use of 23-gauge instruments has advantages over standard 20-gauge equipment. Pars plana/plicata lentectomy using 23-gauge instruments is a safe, effective, and minimally invasive method for treating cataract in babies. PMID: 19513723 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537711 Thu, 04 Jun 2009 23:00:00 +0100 2537711 [Therapeutic options in vernal keratoconjunctivitis] http://www.medworm.com/index.php?rid=2537743&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19430798%26dopt%3DAbstract Authors: Messmer EM Vernal keratoconjunctivitis (VKC) is a chronic, seasonally exacerbated allergic inflammation of the lids, conjunctiva, and cornea. The pathogenesis of VKC is much more complex than a mere type I hypersensitivity reaction. T-cell-mediated responses, eosinophil attraction, and nonspecific immunological reactions are key mechanisms involved. Cytokines, chemokines, proteases, and growth factors play a major pathogenetic role. Therapeutic options in VKC include mast cell stabilizers, antihistamines, corticosteroids, and immunosuppressive drugs. Newer, more selective therapeutic strategies such as antichemokine receptor antibodies, leukotriene receptor antagonists, and specific macrobiomolecules are under evaluation. PMID: 19430798 [PubMed - in process] (Source: Der O... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537743 Sun, 31 May 2009 23:00:00 +0100 2537743 [Pilot study of the Heidelberg diplopia questionnaire] http://www.medworm.com/index.php?rid=2537735&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19484245%26dopt%3DAbstract CONCLUSION: The Heidelberg diplopia questionnaire records patients' subjective complaints concerning diplopia. This study serves as the starting point for further studies in this field. PMID: 19484245 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537735 Sun, 31 May 2009 23:00:00 +0100 2537735 [Genetics of Usher syndrome] http://www.medworm.com/index.php?rid=2537731&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19495774%26dopt%3DAbstract Authors: Bolz HJ Since the first gene (MYO7A) for Usher syndrome was identified 14 years ago, there has been substantial progress in the elucidation of the genetic basis of this disorder, revealing extensive genetic heterogeneity (with nine genes known to date). Most Usher genes have similar functions, localize to similar regions in inner ear hair cells and retinal photoreceptors, and interact with each other. Approximately 80% of the patients carry mutations in one of the known Usher genes. One major challenge for the scientific community is to identify the remaining causative genes. Moreover, it is still largely unclear which genetic factors are responsible for the clinical variability that can be observed even between affected siblings. The establishment of high-throughput technique... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537731 Sun, 31 May 2009 23:00:00 +0100 2537731 [Ocular motility disorders in a patient with Fabry's disease] http://www.medworm.com/index.php?rid=2537717&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19499232%26dopt%3DAbstract We present a 38-year-old male FD patient with a prior history of six different episodes of stroke and newly developing ocular disorders. He presented with nystagmus with different wave forms and directions and blepharospasm as well as cornea verticillata. PMID: 19499232 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537717 Sun, 31 May 2009 23:00:00 +0100 2537717 [Usher syndrome: clinical features, diagnostic options, and therapeutic prospects] http://www.medworm.com/index.php?rid=2537709&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19517115%26dopt%3DAbstract Authors: Seeliger MW, Fischer MD, Pfister M Usher syndrome denotes a clinically and genetically heterogeneous combination of retinitis pigmentosa and sensorineural deafness. The division into subtypes I, II, and III is based on the degree of hearing loss: Type I is characterized by deafness from birth together with ataxia and retarded motor development, type II by a stationary deafness of a moderate degree, and type III by a progressive deafness with adult onset. In Germany, Usher syndrome currently bears particular relevance because in January 2009 a new compulsory screening of auditory function in newborn infants was introduced. Consequently, it can be expected that a higher number of patients with Usher syndrome will be identified in early childhood and referred to ophthalmologists.... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537709 Sun, 31 May 2009 23:00:00 +0100 2537709 [Keratoplasty: laminate or penetrate? Part 1: penetrating keratoplasty] http://www.medworm.com/index.php?rid=2537705&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19543737%26dopt%3DAbstract Authors: Maier P, Reinhard T A number of corneal disorders sooner or later call for a decision as to whether corneal grafting is necessary. The problems of the current gold standard treatment, conventional penetrating keratoplasty (PKP), have yet to be fully solved, namely accelerated postoperative endothelial cell loss, endothelial immune reactions and the induction of astigmatism, which depends among other things on the trephination technique used. The use of a hand trephine may lead to different cutting angles between donor and recipient, resulting in increased postoperative astigmatism. This technique is therefore now only used for certain indications. One major advantage of mechanically guided trephine systems, which are now considered standard, is the possibility of trephining th... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537705 Sun, 31 May 2009 23:00:00 +0100 2537705 [Clinical course of a solitary retinal astrocytoma.] http://www.medworm.com/index.php?rid=2537738&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19484244%26dopt%3DAbstract Authors: Töteberg-Harms M, Paulsen F, Duncker GI, Sel S Retinal astrocytomas are benign tumors of the retina. Their localization can be solitary, multiple, or bilateral in both eyes. It is also known that they can be part of a phakomatosis syndrome (i.e., tuberous sclerosis or neurofibromatosis). Because retinal astrocytomas have a slow growth rate, yearly controls by an ophthalmologist with interdisciplinary consultation are adequate. Some uncommon cases have been reported in which the tumor has grown more aggressively. These tumors may require therapeutic interventions (e.g., vitreoretinal surgery, brachytherapy, photodynamic therapy, or cryotherapy). PMID: 19484244 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537738 Sat, 30 May 2009 23:00:00 +0100 2537738 [Unusual myopic fundus alteration.] http://www.medworm.com/index.php?rid=2537740&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19479266%26dopt%3DAbstract Authors: Münzenberg C, Paulsen F, Kalinski T, Dmitriew A, Duncker GI, Sel S A 44-year-old female patient reported a "black dot" which had been in front of the right eye for more than 4 days and which moved together with eye movements. The optical coherence tomography (OCT) image of the right macula showed large cystic cavities and thickening within the retinal pigment epithelium (RPE) near the fovea centralis as well as small bore cystic alterations, which indicated an event in the region of the choroid. Fluorescein angiography and indocyanine green angiography excluded choroidal neovascularization (CNV). The diagnosis revealed a broad superficial choroidal blood vessel mimicking a subretinal hemorrhage. PMID: 19479266 [PubMed - as supplied by publisher] (Source: Der Ophthalmo... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537740 Fri, 29 May 2009 23:00:00 +0100 2537740 [Central scotoma and blurred vision in a patient with Crohn's disease.] http://www.medworm.com/index.php?rid=2537742&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19440721%26dopt%3DAbstract Authors: Caramoy A, Lappas A, Fauser S, Kirchhof B A 42-year-old male patient was transferred as an emergency with suspected retrobulbar neuritis due to a central scotoma. He had suffered from reduced vision in the right eye in the past. The diagnosis was chronic recurrent retinopathy centralis serosa due to many years of corticosteroid intake for bronchial asthma and Crohn's disease. Photodynamic therapy was carried out on the right eye and the corticosteroids were discontinued. PMID: 19440721 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537742 Thu, 14 May 2009 23:00:00 +0100 2537742 [Topical inhibition of angiogenesis at the cornea : Safety and efficacy.] http://www.medworm.com/index.php?rid=2537755&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19396447%26dopt%3DAbstract CONCLUSIONS: Avastin(R) and GS101 eye drops are the first specific angiogenesis inhibitors for topical inhibition of corneal angiogenesis available for clinical use. PMID: 19396447 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537755 Thu, 30 Apr 2009 23:00:00 +0100 2537755 [Bevacizumab goes anterior : Antiangiogenic therapy at cornea and conjunctiva.] http://www.medworm.com/index.php?rid=2537753&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19396448%26dopt%3DAbstract Authors: Cursiefen C PMID: 19396448 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537753 Thu, 30 Apr 2009 23:00:00 +0100 2537753 [Intravitreal injections of medications in Germany : Contract situation and legal conditions.] http://www.medworm.com/index.php?rid=2537751&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19408003%26dopt%3DAbstract Authors: Ziemssen F, Wiedemann P, Kampik A, Holz F, Bartz-Schmidt KU Despite the increasing application of both approved and off-label drugs for intravitreal administration, the German health system still does not provide an accounting code for the procedure of intravitreal injections. Health insurances and politicians are exerting pressure in order to limit the expected increase in the number of medications and costs due to demographic factors. Although the price for the drug can be determined by the manufacturer, a standing committee has to agree on the fee to be charged for the medical service of injection and subsequent examinations. Until the missing arrangement has been made, each individual surgeon can balance accounts with the patients who have claim for reimbursement. Many con... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537751 Thu, 30 Apr 2009 23:00:00 +0100 2537751 [Antiangiogenic treatment for neovascular glaucoma and after filtering surgery.] http://www.medworm.com/index.php?rid=2537749&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19418055%26dopt%3DAbstract Authors: Lüke J, Lüke M, Grisanti S Bevacizumab is increasingly discussed as adjuvant treatment for rubeosis and for all stages of neovascular glaucoma. In incipient rubeosis bevacizumab has a preventive effect and arrests the progression of disease. In the case of increasing involvement of the anterior chamber angle, bevacizumab should be integrated into stage-adapted treatment to achieve successful control of intraocular pressure. The treatment of the causative ischemic stimulus is necessary in every stage of disease. One further indication for bevacizumab is the postoperative inhibition of angiogenesis after glaucoma surgery. Possible routes of administration are subconjunctival application during trabeculectomy, postoperative needling, or intravitreal injection during a f... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537749 Thu, 30 Apr 2009 23:00:00 +0100 2537749 [Antiangiogenic therapy for pterygium recurrence.] http://www.medworm.com/index.php?rid=2537747&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19418056%26dopt%3DAbstract CONCLUSIONS: Considering the previously multiple recurrences in our patients we think that these first clinical mid-term follow-up experiences support the use of topical VEGF inhibitors in recurrent pterygia. PMID: 19418056 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537747 Thu, 30 Apr 2009 23:00:00 +0100 2537747 [Keratomycosis: diagnosis and therapy.] http://www.medworm.com/index.php?rid=2537745&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19424703%26dopt%3DAbstract Authors: Behrens-Baumann W Diagnosis of fungal keratitis is only straightforward if it presents in its typical form with pyramidal-shaped hypopyon, prominent geographical corneal infiltration and satellites. However, in contact-lens wearers clinical presentation is untypical at early infection. Corneal debridement is therefore necessary, which simultaneously facilitates penetration of the antimycotic into the corneal stroma. At present, voriconazole is the medication of choice, if not changed after microbiological diagnosis to a specifically more potent substance - e.g. posaconazole or caspofungin. Amphotericin B may be used for repeated intracameral or intravitreal injection. Simultaneous application of steroids is useful. PMID: 19424703 [PubMed - in process] (Source: Der Ophthalm... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537745 Thu, 30 Apr 2009 23:00:00 +0100 2537745 [In Process Citation] http://www.medworm.com/index.php?rid=2537701&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19557418%26dopt%3DAbstract Authors: PMID: 19557418 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537701 Thu, 30 Apr 2009 23:00:00 +0100 2537701 [In Process Citation] http://www.medworm.com/index.php?rid=2537700&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19557419%26dopt%3DAbstract Authors: PMID: 19557419 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537700 Thu, 30 Apr 2009 23:00:00 +0100 2537700 [Temporal oscillations of retinal vessel diameter in healthy volunteers of different age.] http://www.medworm.com/index.php?rid=2537757&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19381644%26dopt%3DAbstract CONCLUSIONS: High-frequency oscillations of vessel diameter correspond to the heartbeat. These were expressed more in seniors. Low-frequency oscillations were well expressed in young subjects. Our results show significant age-related alterations in retinal vessel regulation. PMID: 19381644 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2537757 Fri, 17 Apr 2009 23:00:00 +0100 2537757 [Genetic diseases of the retinal pigment epithelium.] http://www.medworm.com/index.php?rid=2314406&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19343351%26dopt%3DAbstract Authors: Preising MN, Lorenz B The retinal pigment epithelium (RPE) is a cellular monolayer between the choriocapillaris and the photoreceptors which controls the uptake of nutrients by the retina and the disposal of shed photoreceptor outer segments from the retina. The RPE is responsible for a continuous supply of rhodopsin by the retinol cycle and blocking of light by its pigmentation to minimize light-induced oxidation of retinal lipids and proteins. Proteins encoded by genes in which mutations are responsible for hereditary disorders of the retina and the RPE are involved in all these functions. In this article these genes and disorders are reviewed in the context of a functional network. PMID: 19343351 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2314406 Sat, 04 Apr 2009 04:00:00 +0100 2314406 [The role of retinal pigment epithelium in visual functions.] http://www.medworm.com/index.php?rid=2314401&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19343352%26dopt%3DAbstract This article summarizes the variety of different functions of the retinal pigment epithelium and describes the failure of those functions which are of most clinical importance. PMID: 19343352 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2314401 Sat, 04 Apr 2009 04:00:00 +0100 2314401 [Functional glaucoma diagnosis.] http://www.medworm.com/index.php?rid=2314396&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19343353%26dopt%3DAbstract Authors: Erb C, Göbel K Achromatic perimetry is the gold standard in glaucoma diagnosis for detecting functional defects from glaucomatous optic neuropathy. Because achromatic perimetry is only able to detect scotomas after loss of up to 30-40% of retinal ganglion cells, early diagnosis using this method is rarely possible. Therefore, a lot of new perimetric procedures have been developed in recent years to detect new scotomas at a very early stage. This review summarizes the theoretical background of retinal ganglion cells in order to better understand the theoretical approaches of new perimetric methods. In addition, the most important commercial perimetric devices currently available are presented. PMID: 19343353 [PubMed - as supplied by publisher] (Source: Der Ophthalmolog... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2314396 Sat, 04 Apr 2009 04:00:00 +0100 2314396 [Clinical manifestations of functional disturbances of the retinal pigment epithelium.] http://www.medworm.com/index.php?rid=2314411&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19340431%26dopt%3DAbstract Authors: Gamulescu MA, Renner AB, Helbig H The retinal pigment epithelium (RPE) serves a variety of different functions and impairment of these functions can lead to a multitude of different diseases of the posterior segment of the eye. The RPE plays an important role as an ion and fluid pump for the reabsorption of subretinal fluid in retinal detachment. On the other hand, defects in this pump function and in the outer blood-retinal barrier formed by the RPE, lead to fluid retention in inflammatory diseases. Metaplasia of RPE cells to myofibroblasts can lead to proliferative vitreoretinopathy and tractive retinal detachment. Early age-related maculopathy is caused by disturbances of phagocytosis and metabolism of the RPE. Imbalance of the physiological equilibrium between vasoprolifer... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2314411 Fri, 03 Apr 2009 04:00:00 +0100 2314411 [Retinal pigment epithelium.] http://www.medworm.com/index.php?rid=2314416&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19330335%26dopt%3DAbstract Authors: Strauß O PMID: 19330335 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2314416 Sun, 29 Mar 2009 04:00:00 +0100 2314416 [Anticipation in patients with iridescent multicoloured posterior capsular lens opacities ("Christmas tree cataract") : The Role in the diagnosis of myotonic dystrophy.] http://www.medworm.com/index.php?rid=2314421&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19326122%26dopt%3DAbstract DISCUSSION: A relationship existed between CTC and manifest DM in 16.7% of the patients with CTC. A hypothesis states that the other 83.3% might have premutations in the DMPK gene, which might lead to a complete mutation after transmission through subsequent generations. In the meantime, molecular genetic DM tests are available. Because of clinical heterogeneity and the anticipation phenomenon in DM, confirmation with such molecular genetic DM tests should be obtained. PMID: 19326122 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2314421 Sat, 28 Mar 2009 04:00:00 +0100 2314421 [Indications and technique of optic nerve sheath fenestration.] http://www.medworm.com/index.php?rid=2290240&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19308418%26dopt%3DAbstract Authors: Lagrèze WA An optic nerve sheath fenestration is indicated when papilloedema leads to progressive visual loss despite previous, conservative measures and when no cause of increased intracranial pressure can be indentified and eliminated. This rather rare constellation usually occurs in idiopathic intracranial hypertension. The procedure is performed via a medial transconjunctival orbitotomy. If headaches and neurologic symptoms other than visual deterioration prevail, the placement of a ventricular shunt is preferred. This review covers the symptoms of idiopathic intracranial hypertension and optic nerve sheath fenestration with its technical aspects and results. PMID: 19308418 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2290240 Wed, 25 Mar 2009 04:00:00 +0100 2290240 [Influence of antiangiogenetic therapy on retinal thickness values in age-related macular degeneration.] http://www.medworm.com/index.php?rid=2290237&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19308419%26dopt%3DAbstract CONCLUSION: This study showed that differences in CRT measurements between different OCT systems were subject not only to technical differences but also to treatment effects of current antiangiogenetic strategies. These effects should be recognized because clinical studies increasingly define OCT parameters as primary or secondary outcome measures. PMID: 19308419 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2290237 Wed, 25 Mar 2009 04:00:00 +0100 2290237 [Computer animated childrens pictures for vision testing.] http://www.medworm.com/index.php?rid=2290236&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19308420%26dopt%3DAbstract CONCLUSION: The animation of optotypes has a favourable effect on the motivation of children. The problem of reduced compliance and concentration can be reduced. The visual acuity scores can be improved by eliminating mistakes caused by low motivation. PMID: 19308420 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2290236 Wed, 25 Mar 2009 04:00:00 +0100 2290236 [Suture management after trabeculectomy.] http://www.medworm.com/index.php?rid=2290248&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19306003%26dopt%3DAbstract Authors: Klink T, Grehn F The frequency of bleb interventions after trabeculectomy is high. In half of the cases suture manipulation of the scleral flap is needed. Both standard and adjustable sutures are used for outflow adjustment of the scleral flap. The long-term results of both methods are equivalent. Open scleral flap revision and transconjunctival sutures are suitable for the treatment of hypotonia. Postoperative conjunctival suture removal seems to be favourable, improving both intraocular pressure and overall success rate. PMID: 19306003 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2290248 Sun, 22 Mar 2009 04:00:00 +0100 2290248 [Cause of a contusion of the eyeball.] http://www.medworm.com/index.php?rid=2290246&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19306004%26dopt%3DAbstract Authors: Bühner E, Weber S, Gentsch D, Meier P A 21-year-old man presented in the emergency department with noticeable deterioration of vision and a feeling of pressure in the right eye. He stated that he had injured his eye when a shot was fired while cleaning a blank cartridge pistol. Ultrasound examination revealed no evidence of intravitreal hemorrhage or detachment of the retina. Examination by computed tomography did not reveal the presence of a foreign body. The severely reduced visual acuity could most likely be attributed to a traumatic cataract. An in-depth psychiatric examination of the anamnesis revealed that the patient had deliberately injured himself with the weapon. The severe traumatic eye injury was the result of an unrecognized hebephrenic schizophrenia. PMI... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2290246 Sun, 22 Mar 2009 04:00:00 +0100 2290246 [Biomechanical condition of the cornea as a new indicator for pathological and structural changes.] http://www.medworm.com/index.php?rid=2290244&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19306005%26dopt%3DAbstract CONCLUSIONS: CRF and CH changes may reflect structural changes of the cornea. Thus, the ORA provides valuable information for a better understanding and characterization of the biomechanical condition of the cornea, especially with regard to diseases such as keratoconus and glaucoma. PMID: 19306005 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2290244 Sun, 22 Mar 2009 04:00:00 +0100 2290244 [Isolated corneal intraepithelial dysplasia.] http://www.medworm.com/index.php?rid=2290242&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19306006%26dopt%3DAbstract We present the case of an 83-year-old patient with an isolated epithelial dysplasia of the cornea. After corneal abrasion the lesion reoccurred 14 days later. The abrasion was then increased to cover the whole corneal epithelium and adjacent limbal and conjunctival areas were also biopsied. Histology revealed a corneal epithelial dysplasia stage 3, whereas the limbal and conjunctival biopsies showed normal epithelium. After resection two cycles of local mitomycin C application (2 cycles of 14 days each) were administered and 9 months after the second intervention the cornea remained clear with good vision. The investigation for human papillomavirus showed a type 6, which is not associated with an increased risk of malignancy. PMID: 19306006 [PubMed - as supplied by publisher] (Source: ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2290242 Sun, 22 Mar 2009 04:00:00 +0100 2290242 [Therapy options for diseases of the lacrimal ducts.] http://www.medworm.com/index.php?rid=2265344&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19283388%26dopt%3DAbstract Authors: Meyer-Rüsenberg HW, Emmerich KH PMID: 19283388 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2265344 Fri, 13 Mar 2009 04:00:00 +0100 2265344 [Microendoscopic tear duct surgery.] http://www.medworm.com/index.php?rid=2265348&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19280195%26dopt%3DAbstract Authors: Emmerich KH, Ungerechts R, Meyer-Rüsenberg HW Transcanalicular microendoscopy of the lacrimal system has brought great advantages in knowledge and our understanding of the pathophysiology of the lacrimal system. It has now been confirmed that the causes of most primary idiopathic stenoses are often spot-like stenoses located at the site of anatomically preformed folds in the efferent tear ducts. Minimally invasive procedures of rechanneling have been developed, such as laser dacryoplasty and microdrill dacryoplasty, which preserve lacrimal pump function, result in much less stress for the patient and for a first-step procedure have an acceptable success rate of 80%. PMID: 19280195 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2265348 Thu, 12 Mar 2009 04:00:00 +0100 2265348 [Higher visual disorders.] http://www.medworm.com/index.php?rid=2265347&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19280196%26dopt%3DAbstract Authors: Wilhelm H Higher visual disorders as discussed in this paper comprise visual hallucinations, palinopsy, hemineglect, Balint Holmes syndrome, prosopagnosia, visual objectagnosia, alexia without agraphia and cerebral achromatopsia. Such disorders are frequently caused by ischemia, but tumors, trauma and intoxication are possible as well. As a rule, higher visual disorders are a transient phenomenon. It is important to inform the patient and his family about the nature of the disorder and consider persisting disorders during rehabilitation. PMID: 19280196 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2265347 Thu, 12 Mar 2009 04:00:00 +0100 2265347 [Epiphora : Age-related changes of the ocular surface, eyelid function and the efferent tear ducts.] http://www.medworm.com/index.php?rid=2265346&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19280197%26dopt%3DAbstract Authors: Schaudig U, Meyer-Rüsenberg H Symptomatic epiphora is predominantly present in the elderly It is caused either by hypersecretion in ocular surface disorders, mostly as a reflex, by decreased tear transport and mechanical stenosis of the efferent tear ducts. These three different causes have to be taken into consideration by differential diagnosis and lead to different forms of therapy. Ocular surface disorders (wet dry eye) are treated by topical medication, lid malfunctioning and dacryostenosis by surgery and possibly by topical adjuvant anti-inflammatory medication. The present article reviews the current concepts on epiphora as an age-associated symptom and the epidemiology and pathogenesis of dacryostenosis and dacryolithiasis. PMID: 19280197 [PubMed - as supplied... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2265346 Thu, 12 Mar 2009 04:00:00 +0100 2265346 [Current status of dacryocystorhinostomy.] http://www.medworm.com/index.php?rid=2265345&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19280198%26dopt%3DAbstract This article reviews the various methods currently in use, although the analysis makes clear how difficult it is to compare studies. Because of the high success rate and the possibility of correcting multiple disturbing factors of the lacrimal drainage system, external DCR remains the gold standard for the ophthalmologist; other methods must be measured by the success rate of external DCR. The future of lacrimal duct surgery lies in a better understanding of wound healing and thus the possibility for precise modulation. Better results may be possible by combining different surgical methods. Prospective studies are urgently necessary. PMID: 19280198 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2265345 Thu, 12 Mar 2009 04:00:00 +0100 2265345 [Procedural guidelines : Good tissue practice for cornea banks.] http://www.medworm.com/index.php?rid=2241845&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19263054%26dopt%3DAbstract Authors: Schroeter J, Maier P, Bednarz J, Blüthner K, Quenzel M, Pruß A, Reinhard T A cornea bank must have an organizational structure in which responsibility and authority to issue directives are clearly defined. It must also use a documented quality management system on the basis of good practice procedures which is maintained to the current standards. The personnel of a cornea bank must be present in sufficient numbers and be suitably qualified. A cornea bank must be in possession of appropriate facilities which are suitable for the main purpose of conservation of donor corneas. All equipment must be designed and maintained corresponding to the intended purpose. Deviations from the stipulated quality and safety standards must give rise to documented investigations which i... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2241845 Fri, 06 Mar 2009 05:00:00 +0100 2241845 [The light-adjustable lens : Principles and clinical application.] http://www.medworm.com/index.php?rid=2241847&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19259687%26dopt%3DAbstract Authors: Hengerer FH, Mellein AC, Buchner SE, Burkhard Dick H Despite improvements in preoperative lens power calculations many patients are in need of spectacle correction to achieve emmetropia and/or optimal distance vision after cataract surgery. A method to adjust residual spherical and astigmatic errors postoperatively in a predictable and non-invasive way is the implantation of the light-adjustable lens (LAL). Selective irradiation of the LAL with UV light (365 nm) using a digital light delivery device enables a customized light pattern for each patient which produces modifications in the lens curvature and lens power by polymerization of silicon monomers in the lens matrix. In Europe this therapeutic option is currently only available in Spain and Germany, therefore, the number ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2241847 Thu, 05 Mar 2009 05:00:00 +0100 2241847 [Treatment of lacrimal stenosis : Causes, diagnostics, and surgical procedures.] http://www.medworm.com/index.php?rid=2241846&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19259688%26dopt%3DAbstract Authors: Bloching MB, Prescher J The nasolacrimal system lies in direct proximity to the nasal cavity and the paranasal sinuses. Consequently, different nasal pathologies may influence the lacrimal drainage system. Hence, a standardized rhinological examination using endoscopy and, when indicated, modern imaging is mandatory to clarify malfunctions of lacrimal drainage. This paper describes the different possible causes and the necessary diagnostic tools from an ENT physician's point of view. Furthermore, the results of a series of 48 patients with endoscopic dacryocystorhinostomy performed between 2005 and 2008 were entered into the study. Follow-up examination of these patients showed satisfactory results in 91% and complete reduction of symptoms in 82%. Accompanying surgical procedu... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2241846 Thu, 05 Mar 2009 05:00:00 +0100 2241846 [The "wet" dry eye.] http://www.medworm.com/index.php?rid=2223643&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19242698%26dopt%3DAbstract Authors: Schargus M, Geerling G Dry eye is a multifactorial disease of the tears and ocular surface that results in symptoms of discomfort, visual disturbance, and tear film instability, with potential damage to the ocular surface. The two main causes are reduced production of aqueous tears and increased evaporation of tears. The evaporative form of dry eye results in ocular surface irritation with a secondary increase in tear production; this presents to the examiner and patient as a wet eye or epiphora. Knowledge and understanding of the basic pathologies and differential diagnoses of dry eye disease are essential to differentiate this very common form of dry eye from disorders of the lacrimal drainage system and to initiate adequate management. PMID: 19242698 [PubMed - as suppli... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2223643 Fri, 27 Feb 2009 05:00:00 +0100 2223643 [Lacrimal system lacerations and their surgical repair.] http://www.medworm.com/index.php?rid=2205569&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19229541%26dopt%3DAbstract Authors: Struck HG In lacrimal system lacerations the canaliculi are involved in 70% of cases and the lacrimal sac and/or nasolacrimal duct in 30%. Lacrimal system lacerations can be the result of sharp or blunt trauma. Nasolacrimal ducts may become obstructed by indirect trauma as an aftereffect of naso-orbital fractures. The epidemiology, main principles of surgical repair of canaliculi and of lacrimal sacs and/or nasolacrimal ducts, special techniques of surgical reconstruction and approximate success rates are reviewed with respect to the outcome of our patient collective compared to the literature. Canalicular and lacrimal sac lacerations need urgent primary microsurgical repair with silicone intubation and paying special attention to the medial nasal canthus. In cases of traumati... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2205569 Sat, 21 Feb 2009 05:00:00 +0100 2205569 [Sympathetic ophthalmia.] http://www.medworm.com/index.php?rid=2173820&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19198848%26dopt%3DAbstract Authors: Pleyer U, Dutescu M Sympathetic ophthalmia is a rare, bilateral granulomatous uveitis that occurs after either surgical or accidental trauma to one eye. The etiology is still not completely clear, but evidence suggests that sympathetic ophthalmia represents an autoimmune inflammatory response against choroidal melanocytes mediated by T cells. Key features are vision impairment and symptoms associated with inflammation. The diagnosis is based on a history of previous ocular trauma or surgery and clinical findings. Differential diagnoses include other causes of granulomatous uveitis, such as Vogt-Koyanagi-Harada disease, sarcoidosis, tuberculosis, and syphilis. Depending on the suspected etiology, treatment of sympathetic ophthalmia consists of systemic anti-inflammatory agents,... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2173820 Sat, 07 Feb 2009 05:00:00 +0100 2173820 [Clinical findings and diagnostics of cone dystrophy.] http://www.medworm.com/index.php?rid=2164153&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19190919%26dopt%3DAbstract CONCLUSION: The diagnosis of cone dystrophy is difficult due to unspecific subjective symptoms and absence of characteristic ophthalmoscopic findings. The differential diagnosis of unexplained visual loss should include cone dystrophy and requires either a full-field or multifocal ERG. PMID: 19190919 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2164153 Thu, 05 Feb 2009 05:00:00 +0100 2164153 [Genetic causes of hereditary cone and cone-rod dystrophies.] http://www.medworm.com/index.php?rid=2157284&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19184602%26dopt%3DAbstract CONCLUSION: Reliable data on the prevalence and incidence of hereditary cone and cone-rod dystrophies and the underlying genetic defects exist only for distinct clinical and genetic entities. Analysis of the known genes results in identification of the genetic defect and mutation in only a subset of patients. PMID: 19184602 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2157284 Sun, 01 Feb 2009 05:00:00 +0100 2157284 [Limbal stem cell deficiency after chemical burns : Investigations on the epithelial phenotype and inflammation status.] http://www.medworm.com/index.php?rid=2131794&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19165487%26dopt%3DAbstract Authors: Pauklin M, Steuhl KP, Meller D Limbal stem cell deficiency (LSCD) is clinically characterized by growth of fibrovascular pannus onto the corneal surface, chronic inflammation and impaired visual acuity. The aim of this study was to characterize the pannus tissue. Total RNA was isolated from six pannus samples and protein from three pannus samples from patients with LSCD caused by chemical burns. Normal human corneal tissue (n=6) and conjunctiva (n=6) were used as control tissues. The expression of the epithelial lineage markers keratin 3 (K3), K19 and MUC5AC, the inflammatory markers IL-1beta, ICAM-1 and VEGF was analyzed by Western Blotting and/or real-time PCR. Normal corneal tissue had a higher expression of K3 and a lower expression of K19 and MUC5AC in comparison to norma... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=2131794 Sat, 24 Jan 2009 05:00:00 +0100 2131794