MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Der Ophthalmologe' source. Wed, 08 Feb 2012 23:31:37 +0100 http://www.medworm.com/index.php?rid=5646271&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22274292%26dopt%3DAbstract [Smart ophthalmologists : Smartphones for nothing and the Apps for free?]. Ophthalmologe. 2012 Jan;109(1):6-7 Authors: Meyer CH PMID: 22274292 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5646271 Sun, 01 Jan 2012 05:00:00 +0100 5646271 http://www.medworm.com/index.php?rid=5646270&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22274293%26dopt%3DAbstract CONCLUSIONS: The increasing distribution of Smartphone "apps" in ophthalmology may have the potential to facilitate patient treatment, data management and communication. PMID: 22274293 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5646270 Sun, 01 Jan 2012 05:00:00 +0100 5646270 http://www.medworm.com/index.php?rid=5646269&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22274294%26dopt%3DAbstract CONCLUSION: The use of "Apps" in medical healthcare, especially for visually impaired persons, has a great potential to achieve a relief in the clinical provision for visually impaired persons with increasing distribution of smartphones and new technical developments. PMID: 22274294 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5646269 Sun, 01 Jan 2012 05:00:00 +0100 5646269 http://www.medworm.com/index.php?rid=5646268&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22274295%26dopt%3DAbstract [Hydrodynamics of aqueous humor in chronic simple glaucoma : Mechanisms of pressure normalization by an artificial outflow system]. Ophthalmologe. 2012 Jan;109(1):30-6 Authors: Niederer P, Fankhauser F, Kwasniewska S Abstract To help elucidate the interplay of physical forces, in particular pressure and flow, controlling the distribution and absorption of aqueous humor in subconjunctival tissue, a recently published computational model was considered where the fluid production in the eye, its removal via the trabecular/uveoscleral pathways and a surgical pathway are taken into account. The target quantity is the intraocular pressure. The surgical outflow pathway is linked to a fluid bleb that is positioned below the subconjunctival tissue and is modeled as a porous medium. ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5646268 Sun, 01 Jan 2012 05:00:00 +0100 5646268 http://www.medworm.com/index.php?rid=5646267&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22274296%26dopt%3DAbstract CONCLUSION: After lowering the critical values the keratometric indices yielded a high discriminative ability for the detection of early KC stages. However, the excellent classification rates for wavefront-based metrics were not achieved. PMID: 22274296 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5646267 Sun, 01 Jan 2012 05:00:00 +0100 5646267 http://www.medworm.com/index.php?rid=5646266&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22274297%26dopt%3DAbstract Authors: Solebo AL, Rahi J, Grehn F Abstract Modern surgical techniques allow congenital cataract surgery to be performed much more successfully. The development of a secondary glaucoma is the most dreaded postoperative complication (one third of all pediatric secondary glaucomas). Due to the limited value of the available literature, data on prevalence are unreliable. A 10-year postoperative incidence of 10-25% is given in the literature for developing secondary glaucoma and the frequency increases with the duration of follow-up. A major risk factor seems to be the age at the time of surgery. The younger the patient is at the time of surgery the higher the risk of secondary glaucoma. A microcornea seems to be another risk factor in multivariate analysis. The following postoperativ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5646266 Sun, 01 Jan 2012 05:00:00 +0100 5646266 http://www.medworm.com/index.php?rid=5646265&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22274298%26dopt%3DAbstract Authors: PMID: 22274298 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5646265 Sun, 01 Jan 2012 05:00:00 +0100 5646265 http://www.medworm.com/index.php?rid=5501306&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22134344%26dopt%3DAbstract Authors: Goebels S, Hasenfus AK, Kellner BK, Löw U, Seitz B Abstract A 40-year-old female chemical laboratory assistant presented at our clinic with chronic conjunctivitis of 4 years' standing. We initially misdiagnosed her symptoms as giant papillary conjunctivitis. Topical treatment failed to produce an improvement and a biopsy was performed. Histopathological analysis showed bilateral follicular lymphoma, a subtype of the B-cell non-Hodgkin lymphoma. The patient was referred for radiotherapy. At follow-up 18 months later the patient was symptom-free. PMID: 22134344 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501306 Sat, 03 Dec 2011 05:00:00 +0100 5501306 http://www.medworm.com/index.php?rid=5501305&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22134345%26dopt%3DAbstract We present the case of a 41-year-old female patient with acute onset of nyctalopia, xanthopsia and impairment of visual field. The ophthalmologic examination revealed peripheral choroidal elevation with accompanying retinal detachment. Due to the the presence of a nanophthalmic eye without any evidence of inflammation or malignant growth, the diagnosis uveal effusion syndrome could be made. PMID: 22134345 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501305 Sat, 03 Dec 2011 05:00:00 +0100 5501305 http://www.medworm.com/index.php?rid=5501304&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22134346%26dopt%3DAbstract Authors: Schrage N Abstract There is uncertainty in ophthalmology concerning the quality and spectral transmission of light of so-called blue filter intraocular lenses (IOL). Clinical users have noticed that such IOL's appear to have different color intensities. The discussion on medical changes by means of such IOL's is dependent on the real light transmission of these IOL's. To add some objective data we compared these IOL's by systematic transmission measurements and observed technical differences of diffraction and geometry as well as transmission differences. The result gives objective indications that differences between blue filter IOL's from different manufacturers are important and are detailed in this paper. PMID: 22134346 [PubMed - as supplied by publisher] (Source: ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501304 Sat, 03 Dec 2011 05:00:00 +0100 5501304 http://www.medworm.com/index.php?rid=5501303&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22134347%26dopt%3DAbstract CONCLUSION: The quality of the G-DRG system is measured by its ability to obtain adequate funding for highly complex and heterogeneous cases. Specific modifications of the G-DRG structures could increase the appropriateness of case allocation for patients with open eye injuries within the G-DRG C01B of the German DRG system 2009. As a result of the present study, cases with amniotic membrane transplantation should not be allocated to the G-DRG C01B. A petition has been presented by the German Association of Ophthalmology (DOG) to the German DRG Institute to restructure the G-DRG C01B. Data-based analysis is an essential prerequisite for a constructive development of the G-DRG system and a necessary tool for the active participation of medical societies in this process. PMID:... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501303 Sat, 03 Dec 2011 05:00:00 +0100 5501303 http://www.medworm.com/index.php?rid=5501314&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130723%26dopt%3DAbstract We report the case history of a 41-year-old patient who, following bronchial infection, presented with progressive ophthalmoplegia in both eyes, dilated pupils unresponsive to light or convergence and ataxia. The suspected diagnosis of Miller-Fisher syndrome was confirmed by the detection of anti-ganglioside GQ1b antibodies. PMID: 22130723 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501314 Fri, 02 Dec 2011 05:00:00 +0100 5501314 http://www.medworm.com/index.php?rid=5501313&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130724%26dopt%3DAbstract CONCLUSIONS: Careful selection of suitable lens design and material according to individual predisposing factors is necessary. This retrospective case study demonstrates that the combination of hydrophilic lens material and a thin lens design may result in early spontaneous IOL dislocation. Furthermore, as established in one case, YAG laser capsulotomy may induce IOL dislocation if the lens design cannot withstand capsular fibrosis. PMID: 22130724 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501313 Fri, 02 Dec 2011 05:00:00 +0100 5501313 http://www.medworm.com/index.php?rid=5501312&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130725%26dopt%3DAbstract We describe a case of branch arterial occlusions combined with central vein occlusion in a female patient who had undergone IFN beta therapy for 10 years. Thromboembolic and cardiovascular risk factors responsible for this event were excluded. The appearance of retinal vein and artery occlusions in our patient indicates an association with the long-term use of IFN beta. PMID: 22130725 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501312 Fri, 02 Dec 2011 05:00:00 +0100 5501312 http://www.medworm.com/index.php?rid=5501311&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130726%26dopt%3DAbstract [Punctate inner choroidopathy - Improvement in vision after anti-VEGF and photodynamic therapy : An 18-month follow-up control.] Ophthalmologe. 2011 Dec 2; Authors: Weiß S, Winter R, Meyer MW Abstract Punctate inner choroidopathy (PIC) is a rare disease which seems to have an inflammatory origin. Treatment is symptom-oriented and the development of choroidal neovascularization (CNV). If CNV is present the trend is towards the use of anti-VEGF (vascular endothelial growth factor) therapy. Oral therapy with steroids should be initially attempted. PMID: 22130726 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501311 Fri, 02 Dec 2011 05:00:00 +0100 5501311 http://www.medworm.com/index.php?rid=5501310&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130727%26dopt%3DAbstract Authors: Papageorgiou E, Gatzioufas Z, Ninios K, Seitz B Abstract Although Valsalva retinopathy is a rare condition, it should be considered in the differential diagnosis of an acute macular hemorrhage in an otherwise healthy young patient. In most cases the patient presents with sudden, painless visual deterioration and a central scotoma. It is essential to immediately acquire a medical history because patients have typically undertaken strenuous physical activity in the recent past. PMID: 22130727 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501310 Fri, 02 Dec 2011 05:00:00 +0100 5501310 http://www.medworm.com/index.php?rid=5501309&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130728%26dopt%3DAbstract This report illustrates peculiarities in the surgical therapy of open angle glaucoma in patients with OI as well as the options for complication management. PMID: 22130728 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501309 Fri, 02 Dec 2011 05:00:00 +0100 5501309 http://www.medworm.com/index.php?rid=5501308&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130729%26dopt%3DAbstract CONCLUSION: An optimized therapy of essential blepharospasm should not only take dose, dose distribution and injections site into account but also injection intervals. Reinjections could be performed if necessary after at least 6 weeks. PMID: 22130729 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501308 Fri, 02 Dec 2011 05:00:00 +0100 5501308 http://www.medworm.com/index.php?rid=5501307&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130730%26dopt%3DAbstract Authors: Stingl K, Schüttauf F, Besch D Abstract A 46-year-old woman presented with a sudden onset of non-traumatic periorbital hemorrhage, painless proptosis, conjunctival chemosis and injection as well as motility restriction of the right eye with double vision. Magnetic resonance imaging (MRI) revealed an extraconal mass in the medial orbit with lateral displacement of the medial rectus muscle and the eyeball without optic nerve involvement. A biopsy led to the diagnosis of non-specific inflammation. This case shows that sudden periorbital hemorrhages can be a sign for idiopathic orbital inflammation. PMID: 22130730 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501307 Fri, 02 Dec 2011 05:00:00 +0100 5501307 http://www.medworm.com/index.php?rid=5501331&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22101919%26dopt%3DAbstract [Eye pain from an interdisciplinary perspective : Gap between clinical relevance and literature confirmation]. Ophthalmologe. 2011 Dec;108(12):1105-6 Authors: Franko Zeitz P PMID: 22101919 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501331 Thu, 01 Dec 2011 05:00:00 +0100 5501331 http://www.medworm.com/index.php?rid=5501330&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22101920%26dopt%3DAbstract This article clarifies such a diagnostic approach and discusses how a rudimentary knowledge of the characteristics of primary headaches is crucial as even though they do not induce ophthalmologic changes they constitute the main reason for the occurrence of ocular pain. PMID: 22101920 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501330 Thu, 01 Dec 2011 05:00:00 +0100 5501330 http://www.medworm.com/index.php?rid=5501329&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130680%26dopt%3DAbstract This article presents neuroophthalmological conditions that may typically cause ocular pain. Particular attention is paid to the description of two cases of headache and facial pain where after a long diagnostic history the correct reason for the pain was only discovered via subtle diagnostic findings. This is exceptionally important as primary headaches are a main reason for ocular pain on the one hand but on the other hand they do not show unambiguous findings, therefore a definite exclusion of primary sources causing the pain is required before making this diagnosis. PMID: 22130680 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501329 Thu, 01 Dec 2011 05:00:00 +0100 5501329 http://www.medworm.com/index.php?rid=5501328&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130681%26dopt%3DAbstract Authors: Kastrup O, Diener HC, Gaul C Abstract Head and facial pain are common in neurological practice and the pain often arises in the orbit or is referred into the eye. This is due to the autonomic innervation of the eye and orbit. There are acute and chronic pain syndromes. This review gives an overview of the differential diagnosis and treatment. Idiopathic headache syndromes, such as migraine and cluster headache are the most frequent and are often debilitating conditions. Trigemino-autonomic cephalalgias (SUNCT and SUNA) have to be taken into account, as well as trigeminal neuralgia. Trigemino-autonomic headache after eye operations can be puzzling and often responds well to triptans. Every new facial pain not fitting these categories must be considered symptomatic and a tho... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501328 Thu, 01 Dec 2011 05:00:00 +0100 5501328 http://www.medworm.com/index.php?rid=5501327&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130682%26dopt%3DAbstract Authors: Neumann A Abstract Ocular and orbital pain are regularly occurring symptoms in ophthalmological clinics and therefore require differentiated clinical diagnostics in order to be able to offer efficient therapy options. An interdisciplinary approach is necessary due to the plenitude of possible causes, these also including otolaryngology diseases because of the anatomical proximity of nasal sinuses and orbital cavities. This paper aims to give an overview of otorhinolaryngological diseases which must be taken into account in the context of ocular and orbital pain. PMID: 22130682 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501327 Thu, 01 Dec 2011 05:00:00 +0100 5501327 http://www.medworm.com/index.php?rid=5501326&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130683%26dopt%3DAbstract Authors: Kirschfeld K, Land MF Abstract Bifocal or multifocal intraocular lenses (IOLs) can be used to replace natural lenses during cataract surgery. These lenses are recommended by cataract surgeons as the replacement lenses of choice when patients wish to avoid wearing spectacles. There are, however, drawbacks to these lenses: one drawback is that the contrast in the images of bifocal and multifocal lenses is reduced as documented in the ophthalmology literature. It is claimed that acuity is similar in multifocal compared to monofocal lenses, however, we show that any loss in contrast inevitably reduces visual acuity. The other drawback is that the sharp in-focus image is always seen superimposed on one or more blurred out of focus images of the same object. In the ophthalmology... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501326 Thu, 01 Dec 2011 05:00:00 +0100 5501326 http://www.medworm.com/index.php?rid=5501321&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130684%26dopt%3DAbstract CONCLUSION: Current changes in lifestyle in terms of the increased use of visual media and a decrease in outdoor activity do not appear to have influenced the seasonal variation in rhegmatogenous retinal detachment. Factors other than light intensity and average temperature that have not yet been evaluated appear to be the cause of these seasonal variations. PMID: 22130684 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501321 Thu, 01 Dec 2011 05:00:00 +0100 5501321 http://www.medworm.com/index.php?rid=5501316&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130685%26dopt%3DAbstract Authors: Leo-Kottler B, Wissinger B Abstract Leber's hereditary optic neuropathy (LHON) is a rare disease primarily affecting the retinal ganglion cells. In most cases patients with LHON develop permanent visual loss with a large central scotoma in the visual field of both eyes. The optic disc becomes partially or completely pale. At the onset of the disease many patients are considered to suffer from an optic neuritis and are treated under the diagnostic and therapeutic regimen of optic neuritis. LHON is mostly only considered when high dose cortisone therapy fails to be effective or the second eye is affected. Thereafter, molecular genetic analysis will prove LHON in these cases. Detailed anamnesis including pedigree analysis in combination with observance of the peripapillary mi... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501316 Thu, 01 Dec 2011 05:00:00 +0100 5501316 http://www.medworm.com/index.php?rid=5501315&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22130686%26dopt%3DAbstract Authors: PMID: 22130686 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5501315 Thu, 01 Dec 2011 05:00:00 +0100 5501315 http://www.medworm.com/index.php?rid=5430236&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090087%26dopt%3DAbstract [Ocular hypertension : What is it actually?]. Ophthalmologe. 2011 Nov;108(11):1005 Authors: Funk J PMID: 22090087 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430236 Tue, 01 Nov 2011 04:00:00 +0100 5430236 http://www.medworm.com/index.php?rid=5430235&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090088%26dopt%3DAbstract Authors: Töteberg-Harms M, Hirn C, Funk J Abstract Ocular hypertension (OHT) describes a condition with elevated intraocular pressure (IOP) above the norm ( > 21 mmHg). By definition the anterior chamber angle is open and there are neither signs of glaucomatous optic nerve damage nor visual field defects. Thus, for the diagnosis of OHT an extensive baseline examination is mandatory in order to rule out pre-existing glaucomatous damage. Patients with ocular hypertension are at a higher risk of developing glaucoma. Therefore, periodical routine examinations with a standardized protocol for specific follow-up examinations are highly recommended. PMID: 22090088 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430235 Tue, 01 Nov 2011 04:00:00 +0100 5430235 http://www.medworm.com/index.php?rid=5430234&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090089%26dopt%3DAbstract [Orbital exenteration : Algorithm for therapy and rehabilitation]. Ophthalmologe. 2011 Nov;108(11):1023-6 Authors: Keutel C, Hoffmann J, Besch D, Reinert S Abstract Various procedures are available for orbital exenteration, mostly for neoplastic disorders, as well as for reconstructive surgery. Within the context of postoperative care prosthetic rehabilitation plays an important role. The specific form of planned epithetic replacement must already be considered in the design of the surgical procedure. PMID: 22090089 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430234 Tue, 01 Nov 2011 04:00:00 +0100 5430234 http://www.medworm.com/index.php?rid=5430233&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090090%26dopt%3DAbstract CONCLUSION: The combination of PDT with bevacizumab in this case series appears to be an effective and safe therapy combination which is suitable as a therapeutic option for patients with chronic CCS without a tendency to recovery. PMID: 22090090 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430233 Tue, 01 Nov 2011 04:00:00 +0100 5430233 http://www.medworm.com/index.php?rid=5430232&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090091%26dopt%3DAbstract [The 2011 julius springer prize for ophthalmology : awarded to prof. Dr. Daniel meller and dr. Mikk pauklin]. Ophthalmologe. 2011 Nov;108(11):1060-1 Authors: Wasser B, Knapp B PMID: 22090091 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430232 Tue, 01 Nov 2011 04:00:00 +0100 5430232 http://www.medworm.com/index.php?rid=5430231&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090092%26dopt%3DAbstract [Prophylaxis and therapy of postoperative endophthalmitis : Criticism of the ESCRS study and the Early Vitrectomy study]. Ophthalmologe. 2011 Nov;108(11):1062-6 Authors: Behrens-Baumann W Abstract Postoperative endophthalmitis often leads to a substantial loss of vision and sometimes to loss of the eye. Occasionally this results in legal disputes during which medical studies will be consulted for reaching a verdict. Both the European Society of Cataract and Refractive Surgeons (ESCRS) study on prophylaxis and the Early Vitrectomy study on the therapy of postoperative endophthalmitis suffer from substantial deficits in essential areas. These studies cannot therefore be utilized as standard operating procedures and guidelines as well as in legal disputes. PMID: 22090092 [... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430231 Tue, 01 Nov 2011 04:00:00 +0100 5430231 http://www.medworm.com/index.php?rid=5430230&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090093%26dopt%3DAbstract Authors: Shmygalev S, Heller AR Abstract Perioperative visual loss (POVL) after nonocular surgery is a rare but unexpected event and represents a devastating complication. It is most often associated with cardiac, spinal as well as head and neck surgery. The etiology of POVL remains incompletely understood. Any portion of the visual system may be involved, from the cornea to the occipital lobe. The most common site of permanent injury is, however, the optic nerve itself and ischemia is the most often presumed mechanism. Multiple factors have been proposed as risk factors for POVL, including long duration in the prone position, decreased ocular perfusion pressure, excessive blood loss and anemia, hypotension, hypoxia, excessive fluid replacement, elevated venous pressure, head posit... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430230 Tue, 01 Nov 2011 04:00:00 +0100 5430230 http://www.medworm.com/index.php?rid=5430229&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22090094%26dopt%3DAbstract Authors: PMID: 22090094 [PubMed - in process] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5430229 Tue, 01 Nov 2011 04:00:00 +0100 5430229 http://www.medworm.com/index.php?rid=5385231&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22033708%26dopt%3DAbstract Authors: Wilhelm H Abstract Patients frequently contact ophthalmologists because of headache or eye pain. Pure ophthalmological disorders are rarely causative (e.g. asthenopia or diseases of the outer eye). It is very important to recognize symptoms and signs of the causative general or neurological disorders. PMID: 22033708 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5385231 Fri, 28 Oct 2011 04:00:00 +0100 5385231 http://www.medworm.com/index.php?rid=5385230&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22033709%26dopt%3DAbstract [Corneal tumour following anterior chamber lens implantation in a patient with Marfan syndrome : Case study of a 57-year-old patient.] Ophthalmologe. 2011 Oct 28; Authors: Lapp T, Birnbaum F, Evert M, Reinhard T, Auw-Hädrich C Abstract A 57-year-old male patient with Marfan syndrome presented at our clinic with a whitish gelatinous corneal tumour in the right eye. The initial examination revealed pronounced corneal oedema, bullous keratopathy, as well as an iris-fixed anterior chamber lens implanted 7 years previously. After the tumour was removed, the anterior chamber lens was explanted and keratoplasty was explanted and a two stage keratoplasty was performed. Histological analysis of the tumour and the cornea revealed vimentin and a number of smooth muscle actin (SMA)-p... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5385230 Fri, 28 Oct 2011 04:00:00 +0100 5385230 http://www.medworm.com/index.php?rid=5385229&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22037835%26dopt%3DAbstract Authors: Handschel J, Naujoks C, Zimmermann A Abstract Orbital pain can be provoked by diseases of the orbital skeleton as well as the maxillary sinus. Infections of the maxillary sinus caused by dental infections (e.g. periodontitis) or root canal treatment represent the majority of these cases followed by injuries of the orbital skeleton. An appropriate medical history usually provides indications for the further diagnostic procedure. In rare cases diseases of the facial skeleton as well as Wegener's granulomatosis can also cause orbital pain. In contrast temporomandibular disorders (TMD) may cause motility disorders and alterations in binocular vision but are not responsible for orbital pain. PMID: 22037835 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5385229 Wed, 26 Oct 2011 04:00:00 +0100 5385229 http://www.medworm.com/index.php?rid=5385228&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22037836%26dopt%3DAbstract CONCLUSIONS: An adverse effect of decompression on the postoperative squint angle was not evident in this study. New induction of diplopia was not observed at all. One possible explanation is the preservation of the medial wall. PMID: 22037836 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5385228 Wed, 26 Oct 2011 04:00:00 +0100 5385228 http://www.medworm.com/index.php?rid=5385227&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22037837%26dopt%3DAbstract Authors: Wahl J Abstract Increased intraocular pressure is currently the only manipulable risk factor for glaucoma. In ocular hypertension the intraocular pressure is increased but the optic nerve head and visual field are thought to show no damage. Classification into glaucoma by means of the optic nerve head is often possible only over a period of time because there is a large overlap between the already pathological and still normal findings. In the Ocular Hypertension Treatment Study (OHTS) the effectiveness of prophylactic treatment was demonstrated. In the OHTS and the European Glaucoma Prevention Study (EGPS) risk factors have been identified, such as increased intraocular pressure, size of the excavation of the optic nerve head, decreased central corneal thickness, increase... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5385227 Wed, 26 Oct 2011 04:00:00 +0100 5385227 http://www.medworm.com/index.php?rid=5385226&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22037838%26dopt%3DAbstract CONCLUSIONS: The preparation of amniotic membranes with the waterjet represents a precise option to mechanically eliminate amniotic epithelial cells from the amniotic membrane. The use of a waterjet cutter as an exclusively mechanical method without enzymatic-chemical substances may be a benefit, as cytotoxic effects on culturing limbal stem cells caused by chemical substances are not present. PMID: 22037838 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5385226 Wed, 26 Oct 2011 04:00:00 +0100 5385226 http://www.medworm.com/index.php?rid=5353145&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22016192%26dopt%3DAbstract Authors: Atili A, Holke K, Karimdadian D, Schittkowski MP Abstract A 22-year-old patient presented with persistent epiphora over a period of about 7 months. The clinical examination revealed a canalicular swelling in both lacrimal ducts, which postoperatively transpired to be an exophytic tumor. The histopathology result of the excised tumor showed an epithelial lesion, a partially inverted papilloma without malignancy. For tumors arising from lachrimal ducts the first-line therapy is complete tumor resection. PMID: 22016192 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5353145 Fri, 21 Oct 2011 04:00:00 +0100 5353145 http://www.medworm.com/index.php?rid=5286611&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21965115%26dopt%3DAbstract [Arguments against pressure-lowering treatment of ocular hypertension : Prophylactic treatment is unnecessary.] Ophthalmologe. 2011 Oct 2; Authors: Stürmer J Abstract The main argument against a pressure-lowering treatment for patients with ocular hypertension (OHT) is the principle of "first do no harm". The imprecision of intraocular pressure (IOP) measurements and the fact that increased IOP is only a risk factor for glaucoma raise major doubts on a clinical definition of OHT. The use of IOP-lowering treatment in the absence of functional or morphological glaucomatous changes should only be initiated if the IOP is very high (>32 mmHg). If the IOP is between 21 and 32 mmHg the glaucoma conversion risk of the individual patient should be estimated. The risk factors a... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5286611 Sun, 02 Oct 2011 04:00:00 +0100 5286611 http://www.medworm.com/index.php?rid=5286615&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21956747%26dopt%3DAbstract Authors: Struck HG, Schrage NF PMID: 21956747 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5286615 Fri, 30 Sep 2011 04:00:00 +0100 5286615 http://www.medworm.com/index.php?rid=5286614&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21956748%26dopt%3DAbstract Authors: Schmidt D Abstract In a 69-year-old man with ochronosis, circumscribed brown-black scleral spots with injection of conjunctival vessels and some small pigmentations of the peripheral superficial cornea occurred. Ochronosis is an autosomal recessive chronic disease, whereby early detection of cardiac valvular defects and arthritis is important particularly in patients who are older than 40 years. PMID: 21956748 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5286614 Fri, 30 Sep 2011 04:00:00 +0100 5286614 http://www.medworm.com/index.php?rid=5286613&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21956749%26dopt%3DAbstract Authors: Peter S, Mestel S, Thaler M, Reichart E, Mennel S Abstract A 53-year-old contact lens wearer on renal dialysis developed visual impairment due to corneal opacity. The opacity was of a crystalline type and diffusely scattered in the anterior cornea. As oxalosis was suspected ascorbic acid was immediately omitted from the dialysis treatment schedule. Within a few weeks the visual acuity recovered and the corneas became nearly clear. The cornea is an uncommon manifestation site for oxalosis. Nevertheless, one should be aware of this possible sign for oxalosis, which can be a life-threatening complication of treatment with high dose ascorbic acid. PMID: 21956749 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5286613 Fri, 30 Sep 2011 04:00:00 +0100 5286613 http://www.medworm.com/index.php?rid=5286612&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21956750%26dopt%3DAbstract Authors: Rohrbach JM, Willmann G, Lisch W Abstract An 81-year-old patient presented for cataract extraction of the right eye. In addition a bilateral disc-like corneal opacity was present which was classified as central cloudy corneal dystrophy of François. This rare and clinically unproblematic condition will be discussed. PMID: 21956750 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5286612 Fri, 30 Sep 2011 04:00:00 +0100 5286612 http://www.medworm.com/index.php?rid=5270078&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21953480%26dopt%3DAbstract CONCLUSIONS: Half-dose PDT is a safe option for patients with long-standing CSR. All patients showed a decrease of retinal thickness, 6 eyes showed a total resolution of subretinal fluid and 5 eyes also showed functional improvement. PMID: 21953480 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5270078 Thu, 29 Sep 2011 04:00:00 +0100 5270078 http://www.medworm.com/index.php?rid=5270079&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21947577%26dopt%3DAbstract Authors: Manousaridis K, Chylak A, Talks SJ Abstract A 24-year-old female patient presented with sudden onset of paracentral visual field defects of the right eye, which were noticed 2 months before the clinical examination. The slit lamp examination of the anterior and posterior segments showed unremarkable findings but three oval, well demarcated, hyporeflective areas were noticed in the right posterior pole in infrared fundus photographs. A similar small area was found in the left posterior pole. Optical coherence tomography (Cirrus OCT) showed a structural defect of the hyperreflective bands of the outer retina. The diagnosis of acute macular neuroretinopathy was made. PMID: 21947577 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5270079 Sat, 24 Sep 2011 04:00:00 +0100 5270079 http://www.medworm.com/index.php?rid=5199232&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904837%26dopt%3DAbstract CONCLUSIONS: To the best of our knowledge this study is the first comparing optic disc parameters of HRT and 3D photography. Mean differences in stereometric parameters did not exceed the known interobserver and intraobserver variability. The combination of non-mydriatic fundus photography and optic disc analysis is a very attractive and time-saving method. However, before progression of early glaucoma can be monitored or suspected glaucoma can be appraised over longer time periods, further studies are needed to clarify test and retest variability. PMID: 21904837 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5199232 Sat, 10 Sep 2011 04:00:00 +0100 5199232 http://www.medworm.com/index.php?rid=5199231&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904838%26dopt%3DAbstract Authors: Neutzner RV, Jäger M, Friedburg C, Deeg CA, Lorenz B Abstract Acute zonal occult outer retinopathy (AZOOR) is a rare disease and is part of the white dot syndrome occurring bilaterally and often asymmetrically in young healthy myopic women. Characteristic findings are distinct focal lesions of the outer segments (OS) of the photoreceptor (PR) layer and abnormalities in fundus autofluorescence (FAF) within the lesions. Currently there is a lack of defined disease criteria, such as specific laboratory findings. Also no effective therapy is known which makes it difficult to diagnose, differentiate and treat AZOOR. Supplementation of antioxidants may become part of therapeutic options in AZOOR. A 19-year-old myopic woman presented with unilaterally reduced visual acuity. Due ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5199231 Sat, 10 Sep 2011 04:00:00 +0100 5199231 http://www.medworm.com/index.php?rid=5167407&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21858523%26dopt%3DAbstract CONCLUSIONS: The results of this study using hypo-osmolar riboflavin solution in a cross-linking procedure for thin corneas showed a stability of keratoconus 1 year after CXL. Application of the hypo-osmolar riboflavin solution prevented cross-linked corneas from developing stromal scars. PMID: 21858523 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5167407 Sat, 20 Aug 2011 23:00:00 +0100 5167407 http://www.medworm.com/index.php?rid=5167406&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21858524%26dopt%3DAbstract Authors: Reinhard T PMID: 21858524 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5167406 Sat, 20 Aug 2011 23:00:00 +0100 5167406 http://www.medworm.com/index.php?rid=5146134&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21853216%26dopt%3DAbstract We present a case of a 76-year-old male whose wife noticed expulsion of a calcified scleral plaque while applying antiglaucoma eyedrops. The local antiglaucoma therapy was stopped and acetacolamide was administered. Local therapy consisted of hyaluronic acid eyedrop and calcium pantothenate and retinol palmiate eye ointment. This treatment led to a rapid reepithelialization. The expulsion of calcified senile scleral plaques is a described complication which can necessitate surgical treatment. PMID: 21853216 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5146134 Fri, 19 Aug 2011 23:00:00 +0100 5146134 http://www.medworm.com/index.php?rid=5146133&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21853217%26dopt%3DAbstract CONCLUSIONS: Stray light and subjective photopic phenomena do not show any basic correlation. Measurements in patients with refractive MIOLs showed less stray light than near segment or diffractive MIOLs. However, refractive MIOLs induced more halos compared to the other groups analyzed. PMID: 21853217 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5146133 Fri, 19 Aug 2011 23:00:00 +0100 5146133 http://www.medworm.com/index.php?rid=5146132&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21853218%26dopt%3DAbstract Authors: Maier AK, Reichenbach A, Rieck P Abstract Paecilomyces lilacinus is a rare cause of contact lens-associated keratitis. The infection is difficult to eradicate because of multiple antifungal drug resistance and has a poor outcome. A female patient developed contact lens-associated keratitis and Paecilomyces lilacinus could be demonstrated in the corneal abrasion. Despite antifungal therapy with voriconazole a keratoplasty à chaud was necessary and a poor final visual acuity could not be avoided. PMID: 21853218 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5146132 Fri, 19 Aug 2011 23:00:00 +0100 5146132 http://www.medworm.com/index.php?rid=5146131&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21853219%26dopt%3DAbstract Authors: Cordes AK, Frentz M, Schrage NF Abstract Chemical burns of the eye are becoming rare due to improvements in occupational protection. Effective decontamination is the foundation for good clinical results of this ophthalmological emergency. The toxicological aspect focuses on classifying the specific toxicity of a chemical substance by evaluating the degree of eye irritation and eye burns. Chemical substances are classified into defined risk levels by specific tests. The traditional ophthalmological approach is based on the clinical presentation of eye burns as a result of contact with a specific toxic substance. In an integral approach it is shown that substance-specific characteristics, such as concentration and specific reactivity as well as individual features, such as m... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5146131 Fri, 19 Aug 2011 23:00:00 +0100 5146131 http://www.medworm.com/index.php?rid=5146135&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21842291%26dopt%3DAbstract Authors: Klingenstein A, Mayer WJ, Rueping J, Miller C, Kampik A, Mino De Kaspar H Abstract A 43-year-old woman presented with a 2-month history of contact lens-associated keratitis and corneal ulceration on the left eye. Without having isolated the pathogenic agent, a calculated anti-infective and anti-inflammatory therapy had already been administered with no signs of improvement. Filamentous fungi (Acremonium sp) were found in the scraping material and the contact lens solution. A keratoplasty à chaud was necessary despite immediate initiation of pathogen-specific therapy. Early identification of the pathogen via corneal debridement and culturing are standard procedures in order to initiate a specific therapy and prevent ulceration which can threaten the visual outcome. PMI... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5146135 Sat, 13 Aug 2011 23:00:00 +0100 5146135 http://www.medworm.com/index.php?rid=5125610&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21822646%26dopt%3DAbstract Authors: Wolff J Aniridia or iris deficiencies can severely affect visual function in mostly younger patients and should therefore be corrected. Currently various technical options for the treatment of iris deficiencies are available. The present review considers the main causes of aniridia and the incidence and summarizes the negative effects on visual function. A brief historical overview of the development of prosthetic iris devices is given. Currently available prosthetic iris devices, mainly iris diaphragm lenses and segmental prosthetic iris devices, are presented along with the specific advantages and disadvantages. The management of patients with iris deficiencies is often challenging due to the great heterogeneity and complexity of the underlying ocular problems. Thus an indiv... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5125610 Sat, 06 Aug 2011 23:00:00 +0100 5125610 http://www.medworm.com/index.php?rid=5125609&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21822647%26dopt%3DAbstract This article describes various techniques for implantation of partial and full prostheses and gives instructions for calculating the implant size. Full prostheses can be combined with other reconstructive measures, such as sutured intraocular lenses and are particularly helpful in silicone oil surgery by avoiding endothelial contact. With careful consideration of the indications and application the flexible iris prosthesis is a valuable extension of the spectrum of reconstructive anterior segment surgery. PMID: 21822647 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5125609 Sat, 06 Aug 2011 23:00:00 +0100 5125609 http://www.medworm.com/index.php?rid=5125612&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21818665%26dopt%3DAbstract Authors: Brauweiler P Iris defects can be congenital, traumatic or iatrogenic in origin and affect either the base of the iris or the stroma including the pupillary margin. A differentiation must be made between the occlusion of iridodialyses, by which the detached iris must be fixed on the sclera and defects of the stroma of the iris where parts of the iris are combined to cover the defect. A wide variety of suture techniques have been suggested over the years for iridoplasty to cover defects. Nowadays it is normal to use iris sutures with a closed anterior chamber, which have all the advantages of minimally invasive surgery. PMID: 21818665 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5125612 Fri, 05 Aug 2011 23:00:00 +0100 5125612 http://www.medworm.com/index.php?rid=5125611&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21818666%26dopt%3DAbstract Authors: Kohnen S PMID: 21818666 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5125611 Fri, 05 Aug 2011 23:00:00 +0100 5125611 http://www.medworm.com/index.php?rid=5076981&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21779960%26dopt%3DAbstract CONCLUSIONS: The German version of the GQL-15 is a potent instrument to evaluate impairment in vision-specific functioning of patients with glaucoma. The GQL-15 values are better correlated with the sensitivity of the eye with the more severe glaucomatous damage. The data can help for a better understanding of individual patient impairment to improve medical advice and therapy of patients with glaucoma. PMID: 21779960 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5076981 Fri, 22 Jul 2011 23:00:00 +0100 5076981 http://www.medworm.com/index.php?rid=5027923&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21725660%26dopt%3DAbstract Authors: Steffen H In children with congenital glaucoma the functional long-term result is often disappointing even if the intraocular pressure is well controlled. The reason for this discrepancy is attributed to amblyogenic factors responsible for interfering with normal visual development. These amblyogenic factors are corneal edema, irregular astigmatism and non-corrected ametropia as monocular causes. Binocular causes are anisometropia-induced suppression and strabismus. Full ametropic correction and a very early prophylaxis and treatment of amblyopia with a close follow-up are mandatory to reduce amblyogenic visual impairment in children with congenital glaucoma. PMID: 21725660 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5027923 Sat, 02 Jul 2011 23:00:00 +0100 5027923 http://www.medworm.com/index.php?rid=5027924&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21720876%26dopt%3DAbstract CONCLUSION: The agreement between subjective refraction and objective measurements of the Nidek-660A of patients following INTRACOR-treatment was good. However there was a significant difference in the cylinder values. Therefore thorough comparison of measurements obtained with the autorefractor and the subjective refraction is recommended. PMID: 21720876 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5027924 Fri, 01 Jul 2011 23:00:00 +0100 5027924 http://www.medworm.com/index.php?rid=5027927&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21717225%26dopt%3DAbstract Authors: Hahn I, Heiduschka P, Endl E, Eter N Nanotechnology, the manufacture and use of structures and implements of around a few 100 nm in size, is becoming a key technology of the twenty-first century. An important element for the manufacture of nanoparticles is gold. Gold nanoparticles can be custom made and chemically modified in their size and form. Initial investigations have shown that they are physiologically non-hazardous. A potential application is in neovascular age-related macular degeneration. Gold nanoparticles of suitable dimensions introduced into newly forming blood vessels can be targeted and heated which selectively destroys these blood vessels. This principle has already been demonstrated in cultivated endothelial cells. PMID: 21717225 [PubMed - as supplied by... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5027927 Thu, 30 Jun 2011 23:00:00 +0100 5027927 http://www.medworm.com/index.php?rid=5027926&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21717226%26dopt%3DAbstract This article will give an overview of the objectives of postoperative perimetry, particularly with respect to the visual field criteria for driving and neurosurgical outcome evaluation. A literature review details the perimetry methods applied in neurosurgical outcome studies. Based on a discussion of methodological difficulties of visual field testing, suggestions for a uniform procedure for perimetric examinations are developed. Only a strict standardization with special consideration of the postoperative interval, examination strategies and quantification of the area of field lost allows meaningful comparisons between operation techniques, surgical approaches, target areas and surgical centres. PMID: 21717226 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5027926 Thu, 30 Jun 2011 23:00:00 +0100 5027926 http://www.medworm.com/index.php?rid=5027925&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21717227%26dopt%3DAbstract We present the case of a young women suffering from unilateral loss of visual acuity after treatment with pipamperone. PMID: 21717227 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5027925 Thu, 30 Jun 2011 23:00:00 +0100 5027925 http://www.medworm.com/index.php?rid=5027928&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21713568%26dopt%3DAbstract Authors: Klink T PMID: 21713568 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=5027928 Wed, 29 Jun 2011 23:00:00 +0100 5027928 http://www.medworm.com/index.php?rid=4983155&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21698447%26dopt%3DAbstract Authors: Baraki H, Petersen J Silicone filling of pseudophakic eyes usually results in strong unilateral hyperopia and binocularity is severely disturbed. This problem can be avoided by designing a concave posterior lens surface with the centre of curvature in the macula (Acri.Lyc 59RET®, haptics in capsular bag, body in vitreous cavity). The prospective study on 40 eyes with idiopathic macular foramen yields a mean refraction difference of 0.22 D with and without oil. The A-constant of the lens was found to be 115.7. Clinically relevant aniseikonia did not occur. The main indication is cataracts combined with diabetic retinopathy. PMID: 21698447 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983155 Thu, 23 Jun 2011 23:00:00 +0100 4983155 http://www.medworm.com/index.php?rid=4983154&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21698448%26dopt%3DAbstract Authors: Mayer C, Cordeiro SA, Khoramnia R Myotonic dystrophy Curschmann-Steinert is a genetic disease which is inherited in an autosomal dominant pattern. Patients usually suffer from myotonia, muscular atrophy and weakness and myopathic facies. Furthermore, patients often present with ophthalmological symptoms with subcapsular cataract and bilateral ptosis being the most frequent ones. Therefore the ophthalmologist can help to detect patients suspected of having this disease and initiate further investigations. Despite clinically distinct findings, the disease is often overlooked because of the diversity of symptoms and clinical manifestations. PMID: 21698448 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983154 Thu, 23 Jun 2011 23:00:00 +0100 4983154 http://www.medworm.com/index.php?rid=4983164&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21688053%26dopt%3DAbstract Authors: Stingl K, Bruckmann A This paper presents a case of ocular involvement during acute renal failure caused by hantavirus. A 34-year-old man suffered from sudden visual loss during acute onset fever with nausea and renal failure. The ophthalmologic examination showed myopia in both eyes and no signs of infection but virological studies revealed an infection with hantavirus. During treatment of the renal failure the myopia improved spontaneously. Transient myopia is a typical ocular involvement during infections with hantavirus which leads to renal failure. PMID: 21688053 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983164 Sat, 18 Jun 2011 23:00:00 +0100 4983164 http://www.medworm.com/index.php?rid=4983165&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21681366%26dopt%3DAbstract CONCLUSION: Retinal perfusion is not linked to the type and topography of disc leakage or the extent and topography of visual field damage in NAION. A global circulatory disorder e.g. due to a compartment syndrome of the optic nerve might account for these results. PMID: 21681366 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983165 Thu, 16 Jun 2011 23:00:00 +0100 4983165 http://www.medworm.com/index.php?rid=4983163&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695604%26dopt%3DAbstract Authors: Lagrèze WA PMID: 21695604 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983163 Tue, 31 May 2011 23:00:00 +0100 4983163 http://www.medworm.com/index.php?rid=4983162&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695605%26dopt%3DAbstract This article illustrates the approach to a detailed clinical and neuroradiological assessment which is mandatory for the care of orbital tumor patients. PMID: 21695605 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983162 Tue, 31 May 2011 23:00:00 +0100 4983162 http://www.medworm.com/index.php?rid=4983161&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695606%26dopt%3DAbstract Authors: Maier W, Ridder G, Kaminsky J, Grosu A Tumors of the posterior orbit require different therapeutic modalities, depending on the histological entity. In the orbit all structures are in close relationship and the endocranium is in the direct proximity. This requires profound knowledge of topographic anatomy and high therapeutic precision. The surgical approach to the posterior orbit via a ventral intraorbital approach is strongly restricted due to the ocular bulb which consumes most space in the anterior orbit. Therefore if the bulb and vision are to be retained extraorbital surgical corridors are predominantly preferred. These are classified into extracranial and intracranial approaches. In detail, the former are medial transethmoidal orbitotomy, caudal transmaxillar orbitotomy... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983161 Tue, 31 May 2011 23:00:00 +0100 4983161 http://www.medworm.com/index.php?rid=4983160&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695607%26dopt%3DAbstract Authors: Metzger MC, Lagrèze WA, Schön R Precise anatomical reconstruction of extensive orbital fractures is a challenging procedure for surgeons. Computer-assisted technologies, anatomical preformed implants and the possibility of acquiring 3D images using cone beam computed tomography are considered as the new standards. In this short review these applications are presented. PMID: 21695607 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983160 Tue, 31 May 2011 23:00:00 +0100 4983160 http://www.medworm.com/index.php?rid=4983159&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695608%26dopt%3DAbstract CONCLUSION: Using dynamic wavefront measurement achieved a sequential analysis of aberrations during accommodation. Significant changes in the lower and higher-order aberrations could be detected. These are additionally varied by the associated pupillary response. Moreover, the synchronicity of wave front reaction in the accommodation process was proven. PMID: 21695608 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983159 Tue, 31 May 2011 23:00:00 +0100 4983159 http://www.medworm.com/index.php?rid=4983158&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695609%26dopt%3DAbstract Authors: Heimann H, Yang Y, Wachtlin J, Pauleikhoff D The treatment of age-related macular degeneration with anti-VEGF medications has resulted not only in significant improvements in eye treatment but also in rising costs of ophthalmological therapy. This new treatment has been rapidly introduced into daily practice in Germany with its social security healthcare system and also in Great Britain with its National Health Service. In both countries the most prevalent treatment scheme currently includes three baseline injections of ranibizumab followed by additional injections depending on persisting disease activity. PMID: 21695609 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983158 Tue, 31 May 2011 23:00:00 +0100 4983158 http://www.medworm.com/index.php?rid=4983157&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695610%26dopt%3DAbstract Authors: Ninios K, Jonescu-Cuypers CP, Seitz B Iris malformations are often associated with malformations of the entire eye and systemic diseases. Malformations of the anterior chamber angle can lead to juvenile glaucoma. Axenfeld-Rieger syndromes have autosomal dominant transmission and are associated with juvenile glaucoma in 50-60% of patients. Besides eye anomalies craniofacial malformations are also typical. The etiology of iridocorneal endothelial (ICE) syndrome is unclear but atypical endothelial cells lead to malformations of the entire anterior eye segment of the eye and glaucoma. Aniridia is a bilateral, congenital malformation which manifests sporadically and transmission is usually autosomal dominant. Glaucoma, malformations of the entire eye and systemic malformations are ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983157 Tue, 31 May 2011 23:00:00 +0100 4983157 http://www.medworm.com/index.php?rid=4983156&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21695611%26dopt%3DAbstract Ophthalmologe. 2011 Jun;108(6):595-596 Authors: PMID: 21695611 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4983156 Tue, 31 May 2011 23:00:00 +0100 4983156 http://www.medworm.com/index.php?rid=4884769&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21618019%26dopt%3DAbstract Authors: Klink T, Grehn F Technical characteristics and a long-term therapeutic strategy due to a long life expectancy play a key role in pediatric glaucoma surgery. The well-established angle surgery (goniotomy and trabeculotomy) achieves successful results in primary childhood glaucoma. Trabeculectomy seems to have been displaced as a secondary approach by glaucoma drainage devices (GDD) in primary childhood glaucoma due to inferior results, especially for children under 3 years of age. Even for secondary childhood glaucoma the results of GDD are encouraging, especially for therapy refractory aphakic glaucoma. In the first 2 years after GDD surgery success rates are about 80% for pediatric glaucoma and the results appear to be independent of the type of glaucoma and implant used. The... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4884769 Fri, 27 May 2011 23:00:00 +0100 4884769 http://www.medworm.com/index.php?rid=4928667&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21607812%26dopt%3DAbstract CONCLUSIONS: Both devices tested in this study showed a high correlation for AL and keratometry measurements. ACD measurements performed with the LENSTAR/BioGraph showed a measurable signal but the prototype calculated a value only in the minority (30%) of cases. This study showed that on the one hand the LENSTAR/BioGraph has the potential to be a reliable and useful machine for clinical everyday routine: This space and time-saving device includes several features which make it a patient and user friendly tool for diagnostics as well as screening. On the other hand we found that the software used in the prototype could be improved especially in order to identify IOLs and to measure reliable ACD values in pseudophakic patients. IOL surfaces did not generate sufficient interference signals i... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4928667 Tue, 24 May 2011 23:00:00 +0100 4928667 http://www.medworm.com/index.php?rid=4928668&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21598054%26dopt%3DAbstract Authors: Lagrèze WA, Rössler J, Illerhaus G, Maier W, Grosu A Tumors of the orbit are diagnosed on clinical and neuroradiological criteria. A biopsy may histologically confirm uncertain mass lesions. The patients' age and medical history predispose for certain tumor entities among the rather heterogenous spectrum of possible diagnoses. The therapy depends on the degree of malignancy and its location within the orbit. Among the different options, surgical excision is the most common followed by radiation therapy either in combination with surgery or alone. Chemotherapy plays a subsidiary role in certain lymphomas or metastases. This review covers the surgical techniques and treatment principles for tumors of the anterior orbit, explains radiotherapy techniques and briefly covers chemo... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4928668 Fri, 20 May 2011 23:00:00 +0100 4928668 http://www.medworm.com/index.php?rid=4928669&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21590350%26dopt%3DAbstract Authors: Borkenstein AF, Hausberger S, Mayer C, Faschinger C Although transient myopia is an extremely rare symptom, systemic diseases which can also lead to a life-threatening condition should also be considered in cases of sudden deterioration of vision. Therefore, the initial diagnosis in an ophthalmological clinic or practice plays a decisive role. PMID: 21590350 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4928669 Wed, 18 May 2011 23:00:00 +0100 4928669 http://www.medworm.com/index.php?rid=4830145&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21538089%26dopt%3DAbstract Authors: Kaminsky J, Ridder GJ, Eckstein A, Metzger M, Beisse F Surgical therapy of Graves' orbitopathy comprises orbital decompression as well as strabismus and lid surgery. The former is primarily carried out during active disease, the latter during inactive disease. Orbital decompression abates increased intraorbital pressure and is thus applicable against dysthyroid optic neuropathy and also reduces exophthalmos. The choice of a specific procedure depends mainly on the experience of the respective center. In this article, the pterional transcranial, transnasal transethmoidal, transconjunctival and swinging eyelid approaches are presented. Eye muscle recession relieves the abnormal tension of fibrotic muscles and thus corrects diplopia. Compared to normal strabismus surgery, the dos... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4830145 Tue, 03 May 2011 23:00:00 +0100 4830145 http://www.medworm.com/index.php?rid=4830144&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21538090%26dopt%3DAbstract Authors: Beisse F, Pieh-Beisse C, Lagrèze WA, Hader C Early diagnosis of Graves' orbitopathy (GO) is important for a timely treatment of the disease. The diagnosis is based on clinical as well as radiological findings. Detailed assessment and follow-up mainly rely on standardized clinical examinations which register symptoms and signs including inflammation, upper lid retraction, exophthalmos, eye muscle involvement and diplopia, corneal involvement, raised intraocular pressure and optic nerve involvement, the latter representing a particular challenge. Each case of GO is classified in terms of severity and activity allowing suitable therapeutic strategies to be derived. PMID: 21538090 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4830144 Tue, 03 May 2011 23:00:00 +0100 4830144 http://www.medworm.com/index.php?rid=4779783&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21533609%26dopt%3DAbstract Authors: Rüfer F Reliable measurements of the intraocular pressure (IOP) are necessary for glaucoma patients. The measuring procedure, anatomical changes of the eye or extraocular influences can lead to errors during applanation tonometry. The IOP is overestimated if measured through the wrong eyepiece of the slit lamp, if a force is interfering with the tonometer arm during the measurement, if the lid comes into contact with the tonometer tip, if blepharospasm occurs, if there is lid retraction or if a Valsalva maneuver is present. An underestimation of the IOP occurs if staining with fluorescein is absent or insufficient, if the illumination is not bright enough, if a corneal stromal edema is present, after LASIK, during accommodation, during repeated measures within a few minutes o... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4779783 Sat, 30 Apr 2011 23:00:00 +0100 4779783 http://www.medworm.com/index.php?rid=4779784&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21528373%26dopt%3DAbstract Authors: Aperlic K, Tietz HJ, Erhard M, Regnath T Filamentous fungal keratitis represents a serious infection of the eye. When corneal infiltrates appear, particularly in those who wear contact lenses, mycological assessment should already be performed initially so that filamentous fungal keratitis can be recognized early and treated. Keratitis caused by Fusarium responds well in most cases to topical therapy with ketoconazole or other antimycotic agents so that surgical intervention is only necessary in advanced or treatment-refractory cases. PMID: 21528373 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4779784 Fri, 29 Apr 2011 23:00:00 +0100 4779784 http://www.medworm.com/index.php?rid=4779786&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21526427%26dopt%3DAbstract Authors: Zorn C, Kook P, Glaser E, Feucht N, Lanzl I, Maier M, Lohmann CP Presented here are two cases of patients with unclear visual loss. A diagnostic assessment with spectral domain optical coherence tomography (Sd-OCT), fluorescein angiography (FLA) and blood analyses was performed due to vitreous clouding. Characteristic FLA findings for papillitis and vasculitis and as yet undescribed morphological Sd-OCT changes in the photoreceptor layer and in the pigment epithelium were found. During the treatment of the diagnosed lues these changes were resolved. The Sd-OCT technique seems to be a useful and effective diagnostic tool for uveitis diagnostics. PMID: 21526427 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4779786 Wed, 27 Apr 2011 23:00:00 +0100 4779786 http://www.medworm.com/index.php?rid=4779785&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21528372%26dopt%3DAbstract Authors: Herwig MC, Hubbard GB, Wells JR, Grossniklaus HE Retinoblastoma is the most common primary intraocular tumor in childhood. Diffuse anterior retinoblastoma is an uncommon variant and usually occurs in comparatively older children. Typically, there is an extensive infiltration of the anterior segment by tumor cells clinically mimicking anterior uveitis with pseudohypopyon. The actual retinal focus is often very small and may not be detected despite a thorough histological examination. In this case report the clinical and histological findings of a diffuse anterior retinoblastoma are described. PMID: 21528372 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4779785 Wed, 27 Apr 2011 23:00:00 +0100 4779785 http://www.medworm.com/index.php?rid=4779788&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21503819%26dopt%3DAbstract CONCLUSIONS: The German translation of the GQL-15 was well accepted by glaucoma patients. In our analysis disability of vision-related activities as expressed in the translated GQL-15 correlated with glaucoma severity. This first use of the translated GQL-15 encourages further studies in German glaucoma patients and their quality of life. PMID: 21503819 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4779788 Tue, 19 Apr 2011 23:00:00 +0100 4779788 http://www.medworm.com/index.php?rid=4779787&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21503820%26dopt%3DAbstract We present two cases with a coloboma of the zonule with different degrees of expression and the most important differential diagnoses are discussed. PMID: 21503820 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4779787 Tue, 19 Apr 2011 23:00:00 +0100 4779787 http://www.medworm.com/index.php?rid=4727271&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21491117%26dopt%3DAbstract This article describes the case of a 49-year-old patient with incomplete Vogt-Koyanagi-Harada syndrome. The anamnesis showed that intermittent alternating visual problems had begun 2 weeks before. The best corrected vision was 0.1 bilateral. In addition to a right-sided anterior uveitis multiple blister-like retinal alterations of both fundi were seen in fundoscopy. The fundoscopic findings could be confirmed by spectral domain optical coherence tomography (SD-OCT) as multiple intraretinal cysts and areas with neurosensory detachment. Topical and systemic steroid therapy resulted in a rapid reduction of these symptoms. The reversal in SD-OCT corresponded with a visual improvement. PMID: 21491117 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727271 Thu, 14 Apr 2011 23:00:00 +0100 4727271 http://www.medworm.com/index.php?rid=4727270&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21491118%26dopt%3DAbstract CONCLUSION: Treatment with PTK is a promising therapeutic option in SND to avoid repeat penetrating keratoplasty, even if the prognosis for the corneal graft is endangered by several risk factors (age of the graft, low endothelial density, subclinical recurrent HSV infection). PMID: 21491118 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727270 Thu, 14 Apr 2011 23:00:00 +0100 4727270 http://www.medworm.com/index.php?rid=4727267&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21491119%26dopt%3DAbstract Authors: Haustein M, Babatz J, Sommer F, Radke J, Hoffmann C, Pillunat LE, Sandner D This case report describes the unilateral acute reduction of vision in the right eye of a 48-year-old woman. The patient was otherwise healthy but 2 days previously had suffered from dizziness and blurred vision. Secondary to this, the patient had already been under dental treatment for 1 week due to gingival swelling. At the first examination a macular branch retinal vein occlusion and Roth spots were found in the right eye by indirect ophthalmoscopy. The immediate diagnostic procedure identified aute amyeloid leukemia (AML) as the cause of the vascular pathology. The AML can be manifested in different ways and the retina is involved in approximately 50% of cases. Due to a secondary hyperviscosity syn... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727267 Thu, 14 Apr 2011 23:00:00 +0100 4727267 http://www.medworm.com/index.php?rid=4727266&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21494817%26dopt%3DAbstract Authors: Mojon D A 28-year-old woman presented with surprisingly asymptomatic bilateral inferior altitudinal visual field defects. Fundoscopy disclosed superior hypoplastic optic discs which was diagnosed as bilateral superior segmental optic hypoplasia. The patient suffered from maternal diabetes and sacral agenesis syndrome, which is also frequently associated with maternal diabetes. PMID: 21494817 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727266 Thu, 14 Apr 2011 23:00:00 +0100 4727266 http://www.medworm.com/index.php?rid=4727274&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21487711%26dopt%3DAbstract CONCLUSION: The findings indicate that stimulation of m4 muscarinic cholinoceptors inhibits the cAMP-PKA pathway in corneal epithelial and endothelial cells resulting in decreased protein kinase A activity. Further work will be needed to clarify the physiological role of this signaling pathway in corneal epithelium and endothelium. PMID: 21487711 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727274 Wed, 13 Apr 2011 23:00:00 +0100 4727274 http://www.medworm.com/index.php?rid=4727276&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21484301%26dopt%3DAbstract This report concerns the case of a 28-year-old female patient who was treated with topical steroids for 2 years following complicated hyperopic LASIK surgery with a re-treatment including a re-lift of the flap. A steroid-induced rise in the intraocular pressure (IOP) was subsequently observed on the treated eye, together with a glaucomatous subtotal destruction of the optic nerve, resulting in a residual vision of 1/15. An erroneously low IOP measurement, which was probably the reason for the delay in detecting steroid-induced glaucoma, has been reported in several cases concerning LASIK patients. The reason for the unusually severe course in the case in question can only be presumed, namely a possible accumulation of fluid at the interface or altered biomechanics following hyperopic LASIK... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727276 Tue, 12 Apr 2011 23:00:00 +0100 4727276 http://www.medworm.com/index.php?rid=4727275&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21484302%26dopt%3DAbstract Authors: Lagrèze WA PMID: 21484302 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727275 Tue, 12 Apr 2011 23:00:00 +0100 4727275 http://www.medworm.com/index.php?rid=4727273&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21487712%26dopt%3DAbstract Authors: Hundertmark P, Dierks P, Gottschalk J, Kreusch T, Wiegand W An 8-month-old infant from Russia with bilateral anophthalmia presented with an expanding orbital tumor. The tumor was extirpated and the histological examination revealed a non-malignant pseudocystic process with residual neuro-ectodermal structures. PMID: 21487712 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727273 Tue, 12 Apr 2011 23:00:00 +0100 4727273 http://www.medworm.com/index.php?rid=4727272&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21487713%26dopt%3DAbstract Authors: Finis D, Stammen J, Gonnermann J The case of a 35-year-old pregnant patient is described who presented with acute bilateral visual loss. As the reason for this a retinal arteritis could be demonstrated. The patient also suffered from acute unilateral hearing loss in combination with cerebral changes detectable by MRI. After exclusion of other causes the diagnosis of Susac syndrome (retinocochleocerebral microangiopathy) was made and appropriate therapy was initiated. PMID: 21487713 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727272 Tue, 12 Apr 2011 23:00:00 +0100 4727272 http://www.medworm.com/index.php?rid=4727277&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21468658%26dopt%3DAbstract Authors: Ehrt O Refractive errors are the most common visual problem in children apart from squinting. Indications for spectacles include amblyopia prophylaxis and treatment, strabismus, myopia and reading disorders. Objective refraction by retinoscopy is the central part of prescribing spectacles to children. A slight under correction (maximum of 0.5 dpt in cases with and 1.0 dpt without squint) can be considered in hyperopia only. Myopia, astigmatism and anisometropia must be fully corrected. Any prescription must mention "MA=PD" and "plastic lenses" as well as "high bifocal" if needed. Information to the parents is essential for good compliance of spectacle wear. Step-by-step instructions and a list of possible errors will be given. PMID: 21468658 [PubMed - as supplied by publis... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4727277 Wed, 06 Apr 2011 23:00:00 +0100 4727277 http://www.medworm.com/index.php?rid=4671724&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21448683%26dopt%3DAbstract ["Herpetic keratitis" : Various expressions require different therapeutic approaches.] Ophthalmologe. 2011 Mar 31; Authors: Seitz B, Heiligenhaus A Herpes simplex virus (HSV) is a common cause of keratitis. "Herpetic keratitis" is a chameleon, which is well treatable today if the various types of clinical expression of this disease are known to the ophthalmologist and treatment is adjusted accordingly. Types of expression include 1. epithelial keratitis (dendritica/geographica), 2. stromal keratitis (necrotizing vs. non-necrotizing = "interstitial keratitis"), 3. endotheliitis (=disciform keratitis), 4. neurotrophic keratopathy (=so-called metaherpetic keratitis) and 5. (vascularized) corneal scars. A concomitant ocular hypertension should be treated predominantly non-surgicall... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4671724 Wed, 30 Mar 2011 23:00:00 +0100 4671724 http://www.medworm.com/index.php?rid=4671725&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21431958%26dopt%3DAbstract CONCLUSIONS: The melanoma still contained vital and even single proliferating cells, but regressed afterwards without additional therapy. PMID: 21431958 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4671725 Fri, 25 Mar 2011 00:00:00 +0100 4671725 http://www.medworm.com/index.php?rid=4671727&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21424421%26dopt%3DAbstract Authors: Pielen A, Junker B, Goldammer L, Schumacher M, Feltgen N Ocular ischemic syndrome (OIS) is a group of ocular diseases caused by chronic artery occlusion usually involving the internal carotid artery. Patients suffer from visual loss and pain. OIS is a rare disease which can be confounded with diabetic retinopathy or an older central retinal vein occlusion. The only therapy is to treat the neovascular complications. Due to the high mortality of OIS patients, medical and neurological examinations are mandatory. We discuss the clinical findings and diagnostic and therapeutic options of OIS patients in this paper. PMID: 21424421 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4671727 Thu, 17 Mar 2011 00:00:00 +0100 4671727 http://www.medworm.com/index.php?rid=4671726&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21424422%26dopt%3DAbstract DISCUSSION: The EFQM model is a challenging quality management model. After the necessary training of project members or under the supervision of experienced quality managers, the EFQM model may be successfully applied to patient care, teaching and research in a department of ophthalmology. PMID: 21424422 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4671726 Sat, 12 Mar 2011 00:00:00 +0100 4671726 http://www.medworm.com/index.php?rid=4671728&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21424420%26dopt%3DAbstract DISCUSSION: German cornea banks are currently facing new regulatory issues due to updated legislation regarding tissue transplantation. Recent updates in European law have limited the cutoff time for postmortem blood sampling to 24 h, and this regulation may lead to a significant reduction in potential donors. PMID: 21424420 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4671728 Fri, 11 Mar 2011 00:00:00 +0100 4671728 http://www.medworm.com/index.php?rid=4552838&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21369866%26dopt%3DAbstract [Biologics : From the "golden calf" to a "gold standard"?] Ophthalmologe. 2011 Mar 4; Authors: Pleyer U PMID: 21369866 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4552838 Fri, 04 Mar 2011 00:00:00 +0100 4552838 http://www.medworm.com/index.php?rid=4552839&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21359550%26dopt%3DAbstract CONCLUSION: The ELT is easy to perform at the end of cataract surgery. Duration of surgery is only prolonged by 2 to 3 minutes. We found an average IOP reduction of 8.79 mmHg (-34.70%) and an average reduction of 0.79 AGD. It is known that the effect of IOP reduction is constant over time unlike argon or selective laser trabeculoplasty. If needed later on, filtering surgery is not compromised because there is no conjunctival touch during ELT and therefore no scarring of the conjunctiva. For a selected collective of glaucoma patients this procedure could be a good way to avoid trabeculectomy. PMID: 21359550 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4552839 Sun, 27 Feb 2011 00:00:00 +0100 4552839 http://www.medworm.com/index.php?rid=4552844&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21350866%26dopt%3DAbstract Authors: Goebels SC, Löw U, Schnaidt AC, Seitz B A 44-year-old patient with a known history of Crohn's disease come to our clinic with unilateral vision impairment, orbital pain, and papillary swelling. The patient was treated with methylprednisolone for 5 days. Differential diagnosis excluded ischemic, inflammatory, and tumor-related causes of the papillary swelling, which was more likely to be due to papillitis associated with the known presence of Crohn's disease. Under steroid treatment visual acuity increased from 0.1 to 0.5, and an evident improvement of the ophthalmological and neurological findings was observed. Papillitis in conjunction with Crohn's disease is a rare cause of papillary swelling and should be taken into consideration during differential diagnosis. The disorde... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4552844 Sat, 26 Feb 2011 00:00:00 +0100 4552844 http://www.medworm.com/index.php?rid=4552842&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21350867%26dopt%3DAbstract Authors: PMID: 21350867 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4552842 Sat, 26 Feb 2011 00:00:00 +0100 4552842 http://www.medworm.com/index.php?rid=4552841&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21350868%26dopt%3DAbstract Authors: Stübiger N, Winterhalter S, Pleyer U, Doycheva D, Zierhut M, Deuter C Interferon alpha (IFN-α) and interferon beta (IFN-β) are naturally occurring cytokines, which belong to the type I interferons and share the same receptor leading to very similar therapeutic effects. The immunomodulatory effect of type I interferons includes modulation of antibody production, inhibition of lymphocyte proliferation, inhibition of delayed-type hypersensitivity and enhancement of T-cell and NK-cell cytotoxicity. An increasing number of open clinical studies and case reports have demonstrated the efficacy of IFN-α for severe ocular inflammation in patients with Behçet's disease and of interferon-β, which has been used mainly for the treatment of multiple sclerosis. PMID: 21350868 [PubM... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4552841 Sat, 26 Feb 2011 00:00:00 +0100 4552841 http://www.medworm.com/index.php?rid=4552840&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21350869%26dopt%3DAbstract Authors: Mackensen F, Lutz T Pediatric uveitis differs from uveitis seen in adulthood not only because of the uveitis presentation and severity of disease but also by a worse prognosis and age-specific problems that may occur under therapy. Biologics are selective acting proteins that are manufactured by biotechnology. The greatest amount of knowledge to date exists for the TNF alpha blocking agents. Experimental and clinical studies showed that TNF alpha plays a significant role in the process of intraocular inflammation, so it was a logical step to use TNF blocking agents in uveitis therapy. Randomized controlled studies are rare, but pooled data (as presented here) of case series published show good evidence for the efficacy especially of infliximab and adalimumab. It is to be hoped... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4552840 Sat, 26 Feb 2011 00:00:00 +0100 4552840 http://www.medworm.com/index.php?rid=4552845&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21344246%26dopt%3DAbstract We report the case of a 37-year-old patient with ocular complications associated with the implantation of cosmetic iris implants. Implantation of silicone iris implants for the purpose of changing iris colour has been performed since 2004. Diaphragms are implanted in the anterior chamber. Up to now only little information exists about side effects of this method. In the literature severe ocular complications shortly after cosmetic iris implantation are reported in single cases. In our case 5 months after surgery optic nerve damage caused by elevated intraocular pressure (IOP) was diagnosed. Nuclear opacity of both lenses and a decreased number of corneal endothelial cells were observed at the first visit. Because of recurrent IOP elevation despite maximum antiglaucoma therapy, explantatio... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4552845 Thu, 24 Feb 2011 00:00:00 +0100 4552845 http://www.medworm.com/index.php?rid=4498841&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21327947%26dopt%3DAbstract Authors: Zimmermann A, Lorenz B, Schmidt W A poor general condition of patients with hemorrhagic fever and elevated creatinine should raise suspicion of a systemic infection with Hantavirus. This can often also cause ocular changes. Above all, changes of intraocular pressure, in our case bilateral acute angle-closure glaucoma, due to edema and hemorrhage in the ciliary body result in anterolateral rotation of the iris-lens diaphragm with closure of the chamber angle. It can also cause a transient myopia, and intraretinal hemorrhages can also occur. Hantavirus infection is mostly transmitted through red-backed voles in Europe. The predominant type in Europe is the Puumala virus that can lead to an epidemic nephropathy with high fever, headache, gastrointestinal complaints, and an impair... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4498841 Fri, 18 Feb 2011 00:00:00 +0100 4498841 http://www.medworm.com/index.php?rid=4439906&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21293865%26dopt%3DAbstract This article presents the current DRGs since the discontinuation of care payments and explains how profits can be made applying the DRG system. Important issues such as base rate, cost weight, case mix or case mix index are discussed. The key figures for hospitals in terms of budget calculation are presented. Average inpatient stays were shortened following the introduction of DRGs in Germany. The relevance of surcharges and deductions in the case of non-observance of prescribed patient stays is discussed. PMID: 21293865 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439906 Sat, 05 Feb 2011 00:00:00 +0100 4439906 http://www.medworm.com/index.php?rid=4439907&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21287178%26dopt%3DAbstract Authors: Kuhli-Hattenbach C, Miesbach W, Scharrer I, Hattenbach LO Over the past years there has been a dramatic increase in the number of identifiable causes of thrombophilia. However, as retinal vein occlusions (RVO) have a strong pathogenic correlation with the presence of hypertension or arteriosclerosis and the average age of affected patients is usually within the sixth or seventh decade of life, thrombophilia screening of RVO patients poses a particularly difficult diagnostic challenge. It is clear that to use medical resources appropriately and improve the level of interdisciplinary patient care in RVO, subgroup analysis is required. Just recently, some studies have demonstrated the significant role of coagulation disorders in specific subgroups of RVO patients and have provide... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439907 Thu, 03 Feb 2011 00:00:00 +0100 4439907 http://www.medworm.com/index.php?rid=4439911&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21271253%26dopt%3DAbstract Authors: Salgado JP, Khoramnia R, Maier MM, Lohmann CP, Winkler von Mohrenfels C A patient undergoing combined therapy of chronic hepatitis C with pegylated interferon-α-2a (PEG-IFN-α-2a) and ribavirin suddenly developed severe loss of visual acuity. A central vein occlusion with macular edema was found and intravitreal injections of bevacizumab were initiated. Retinal occlusion is a known complication of therapy with pegylated interferon-α-2a and ribavirin. An interdisciplinary assessment of patients treated for a chronic hepatitis C as well as an early anti-VEGF administration can be helpful in the therapy of this complication of chronic hepatitis C. PMID: 21271253 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439911 Fri, 28 Jan 2011 00:00:00 +0100 4439911 http://www.medworm.com/index.php?rid=4439910&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21271254%26dopt%3DAbstract Authors: Mayer C, Glaser E, Khoramnia R The choroidal osteoma is a typically unilateral, benign ossifying tumor of the choroid. It is mostly located in the juxtapapillary area and usually found in females in the second or third decade of life. Most patients are asymptomatic. However, some can present with blurred vision, metamorphopsia, and visual field defects. Ultrasonography can show a calcified choroidal plaque with a typical shadowing posterior to the lesion. Fluorescein angiography and optical coherence tomography should be used if choroidal neovascularization is suspected as a possible complication of the choroidal osteoma. PMID: 21271254 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439910 Fri, 28 Jan 2011 00:00:00 +0100 4439910 http://www.medworm.com/index.php?rid=4439909&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21271255%26dopt%3DAbstract CONCLUSIONS: Overall, the FKS satisfactorily complies with psychometric standards. Therefore, it can be applied to assess children's vision-related quality of life. PMID: 21271255 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439909 Fri, 28 Jan 2011 00:00:00 +0100 4439909 http://www.medworm.com/index.php?rid=4439908&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21271256%26dopt%3DAbstract Authors: Bock F, Regenfuß B, Cursiefen C There are numerous indications for local antiangiogenic therapy at the ocular surface. These include vision-limiting corneal neovascularization, corneal blood and lymphatic vessels endangering corneal graft survival and tumor-associated lymphangiogenesis. A literature review in PubMed and own clinical and experimental data form the basis for a discussion of the indications, current therapeutic options and potential side-effects of local antiangiogenic therapy at the ocular surface. PMID: 21271256 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439908 Fri, 28 Jan 2011 00:00:00 +0100 4439908 http://www.medworm.com/index.php?rid=4439913&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21267723%26dopt%3DAbstract We present the case of a 52-year-old female patient who presented with bilateral loss of vision over the course of several years. Funduscopy revealed multiple drusen in a "honeycomb"-like configuration at the entire posterior pole and in the peripapillary region. Autofluorescence and fluorescence angiography (FLA) showed multiple hyperfluorescent defects which show no leakage due to staining of the drusen-like lesions. Optical coherence tomography (OCT) revealed a marked irregularity of the photoreceptor-retinal pigment epithelium complex. Electroretinography (ERG) was without pathological findings, while the electrooculography (EOG) was abnormal, reflecting a functional disturbance of the retinal pigment epithelium. In consideration of all clinical findings, our patient suffered from Doyn... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439913 Thu, 27 Jan 2011 00:00:00 +0100 4439913 http://www.medworm.com/index.php?rid=4439912&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21267724%26dopt%3DAbstract Authors: Hattenbach LO PMID: 21267724 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439912 Thu, 27 Jan 2011 00:00:00 +0100 4439912 http://www.medworm.com/index.php?rid=4439915&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21253746%26dopt%3DAbstract Authors: Pieh-Beisse C, Lagrèze WA Nystagmus can be associated with strong discomfort due to oscillopsia, blurry vision and dizziness. Since generally no curative treatment methods exist, studies focus on potential pharmaceuticals to dampen the nystagmus. An overview is given on which forms of nystagmus can be treated with what kind of pharmacological substances and their possible mechanism of nystagmus dampening. Controlled studies found gabapentin and memantine to be effective in acquired pendular nystagmus and early-onset idiopathic nystagmus, and an efficacy of 4-aminopyridine in downbeat nystagmus. PMID: 21253746 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439915 Sat, 22 Jan 2011 00:00:00 +0100 4439915 http://www.medworm.com/index.php?rid=4439914&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21253747%26dopt%3DAbstract CONCLUSION: The results show that sorafenib has promising properties as a potential antiangiogenic treatment for AMD. PMID: 21253747 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439914 Fri, 21 Jan 2011 00:00:00 +0100 4439914 http://www.medworm.com/index.php?rid=4439919&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21253742%26dopt%3DAbstract Authors: Frey O, Kamradt T Biologics and especially therapeutic monoclonal antibodies have an ever increasing impact in the therapy of inflammatory and malignant diseases. They allow a selective blockade of cytokines, receptors and other molecules. This review summarizes the immunological background, the current state and future trends in the development of these therapeutic agents. PMID: 21253742 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439919 Sat, 01 Jan 2011 00:00:00 +0100 4439919 http://www.medworm.com/index.php?rid=4439918&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21253743%26dopt%3DAbstract Authors: Barisani-Asenbauer T Biologics are increasingly being used in the treatment of non-infectious sight-threatening uveitis. While the advantages of biologics, such as avoidance of glucocorticoid side-effects or rapid control of intraocular inflammation therapy refractive to corticosteroids, cannot be dismissed the treating ophthalmologist should be aware of the specific risks. Biologics increase the risk for severe and atypical infections, lymphomas and other malignancies. Treatment should only be initiated when profound knowledge about indications, management and monitoring of treatment with biologics is readily available. Weighing up the risks versus the benefits should be made on an individual basis and guide patient consultation. PMID: 21253743 [PubMed - as supplied by pu... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439918 Sat, 01 Jan 2011 00:00:00 +0100 4439918 http://www.medworm.com/index.php?rid=4439917&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21253744%26dopt%3DAbstract Ophthalmologe. 2011 Jan;108(1):73-84 Authors: PMID: 21253744 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4439917 Sat, 01 Jan 2011 00:00:00 +0100 4439917 http://www.medworm.com/index.php?rid=4374431&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21184233%26dopt%3DAbstract Authors: Pleyer U PMID: 21184233 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374431 Fri, 24 Dec 2010 00:00:00 +0100 4374431 http://www.medworm.com/index.php?rid=4374434&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21181167%26dopt%3DAbstract Authors: Finger RP, Coch C, Coenen M, Mengel M, Hartmann G, Holz FG The proof of a drug's efficacy in randomized controlled trials is fundamental to therapeutic concepts determined by evidence-based medicine. Clinical trials according to the German Medicinal Products Act are performed by the pharmaceutical industry as company-sponsored trials (CST) driven by commercial interests or by non-commercial facilities as investigator-initiated trials (IIT), typically implemented by University Hospitals. In areas with no commercial interest, IITs are the driving force that generate scientific progress leading to treatment optimization. Therefore, non-commercial or investigator-initiated clinical trials are indispensable for improving medical care. To ensure the safety of trial participants and ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374434 Thu, 23 Dec 2010 00:00:00 +0100 4374434 http://www.medworm.com/index.php?rid=4374433&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21181168%26dopt%3DAbstract CONCLUSIONS: Even patients at risk for cardiovascular accidents should not be treated with a combination therapy of ranibizumab and pegaptanib as this combination results in a decline of visual acuity during upload. PMID: 21181168 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374433 Thu, 23 Dec 2010 00:00:00 +0100 4374433 http://www.medworm.com/index.php?rid=4374432&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21181169%26dopt%3DAbstract Authors: Pleyer U, Mackensen F, Winterhalter S, Stübiger N Biologicals are selectively acting proteins that demonstrated high efficacy in the treatment of chronic disorders. In particular, biologicals blocking tumor necrosis factor α (TNF-α), an essential cytokine in chronic inflammatory diseases, have demonstrated great promise. Experimental and clinical data indicate that TNF-α plays an important role in intraocular inflammation. Neutralization of TNF-α might therefore be a promising strategy for prevention and treatment of uveitis. Here we review the principle effects, therapeutic value, and potential side effects of anti-TNF agents in uveitis. PMID: 21181169 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374432 Thu, 23 Dec 2010 00:00:00 +0100 4374432 http://www.medworm.com/index.php?rid=4374441&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21174099%26dopt%3DAbstract We report on a patient who had a foreign body in the optic nerve for 30 years. Histochemical analysis of the optic nerve after the requisite enucleation with complete functional loss of the eye revealed amazing results. Even 30 years after entry of the foreign body into the optic nerve neuronal structures with organized axons surrounded by cytoblasts, glial cells, and immunocompetent cells still remoined. These findings hold out hope and may serve as the starting point for regenerative medicine to potentially restore neuronal function. PMID: 21174099 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374441 Wed, 22 Dec 2010 00:00:00 +0100 4374441 http://www.medworm.com/index.php?rid=4374444&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21170651%26dopt%3DAbstract CONCLUSION: Imaging sclerotomies ex vivo by ultrasound biomicroscopy is reliably reproducible. In the echographic pictures straight 20 gauge incisions appeared to be safely sealed by the sutures while the nonsealed tunnels often showed continuous patency. By choosing small instruments and flat incision angles the width of the resulting scleral channels can be reduced. PMID: 21170651 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374444 Sun, 19 Dec 2010 00:00:00 +0100 4374444 http://www.medworm.com/index.php?rid=4374443&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21170652%26dopt%3DAbstract CONCLUSION: Successful treatment of exudative AMD requires small intervals between diagnosis and first ranibizumab injection. After diagnosis, the first injection with ranibizumab should be given as early as possible. PMID: 21170652 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374443 Sun, 19 Dec 2010 00:00:00 +0100 4374443 http://www.medworm.com/index.php?rid=4374442&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21170653%26dopt%3DAbstract DISCUSSION: Topographic and objective astigmatisms were highest for the IR suturing technique. Topographic astigmatism and refractive cylinder were less in the DR (compared to SR) group 4 and 12 months after surgery (statistically significant). After suture removal (2 years after PK) refractive cylinder was still lower for DR compared to SR but there was no statistical difference between DR and SR regarding topographic and objective cylinders. For the interpretation of these data it should be emphasized that due to the retrospective character of this analysis the number of patients in the subgroups is decreasing with time and as a consequence single (strongly deviating) measurements can have a more powerful impact on the outcome in the individual subgroups. PMID: 21170653 [PubMed - as ... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374442 Sun, 19 Dec 2010 00:00:00 +0100 4374442 http://www.medworm.com/index.php?rid=4374446&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21165623%26dopt%3DAbstract CONCLUSIONS: Canaloplasty showed a good IOP-reducing effect. Complications occurred mostly temporarily and were of a controllable nature. PMID: 21165623 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374446 Sat, 18 Dec 2010 00:00:00 +0100 4374446 http://www.medworm.com/index.php?rid=4374445&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21165624%26dopt%3DAbstract Authors: Mayer WJ, Remy M, Rudolph G Kearns-Sayre syndrome is a rare mitochondrial disease which usually occurs sporadically with the presence of ptosis and the clinical triad of chronic progressive external ophthalmoplegia, atypical retinitis pigmentosa and cardiac conduction disorders. We show on the example of a young patient with unexplained atypical acquired ptosis and eye movement disorders, the correct interpretation of the diagnostic findings. Of importance is the early detection of potentially life-threatening complications which can lead to sudden cardiac death. PMID: 21165624 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374445 Sat, 18 Dec 2010 00:00:00 +0100 4374445 http://www.medworm.com/index.php?rid=4374448&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21161236%26dopt%3DAbstract We present a rare case of spontaneous phacolysis with consecutive anterior uveitis in a patient with anterior polar cataract. Despite an intact appearing anterior lens capsule cells were found in the anterior chamber as well as a white mass in the inferior chamber angle. After failure of absorption under topical steroid treatment surgical treatment with capsulorhexis, phacoemulsification and implantation of a intraocular posterior chamber lens in the capsular bag was performed uneventfully. Postoperatively, rapid regression of the inflammatory reaction was observed. PMID: 21161236 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374448 Fri, 17 Dec 2010 00:00:00 +0100 4374448 http://www.medworm.com/index.php?rid=4374447&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21161237%26dopt%3DAbstract We describe the case of a 3-month-old infant suffering from rapidly progressive orbital capillary hemangioma which we treated with systemic propranolol over a period of 3.5 months. A few weeks after the onset of treatment, the exophthalmus had regressed and after 3 months of treatment the tumor completely vanished. This result is consistent with recent publications and supports the role of propranolol in the treatment of problematic hemangioma. PMID: 21161237 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374447 Fri, 17 Dec 2010 00:00:00 +0100 4374447 http://www.medworm.com/index.php?rid=4374440&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21174100%26dopt%3DAbstract CONCLUSIONS: The iCare rebound tonometer is useful during general anesthesia in cases of childhood glaucoma. It provides comparable IOP values to applanation tonometry with a tendency to record higher values. PMID: 21174100 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374440 Wed, 15 Dec 2010 00:00:00 +0100 4374440 http://www.medworm.com/index.php?rid=4374435&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21174101%26dopt%3DAbstract Authors: Witteborn M, Mennel S Orbital cellulitis is an acute inflammation of the orbital content with exophthalmos, chemosis, blepharedema, reduction of eyeball motility and generalized illness, occasionally with fever. It is predominantly transmitted from the ENT region and rarely occurs as a complication after a scleral buckling procedure. The patient concerned contracted orbital cellulitis many years after scleral buckling because the cerclage was infected. Alterations to the sclera with atrophy and thinning in the context of myopia were probably favorable factors for development. PMID: 21174101 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4374435 Wed, 15 Dec 2010 00:00:00 +0100 4374435 http://www.medworm.com/index.php?rid=4289014&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21153829%26dopt%3DAbstract Authors: Pfrommer S, Maier M, Mayer C, Erben A, Engelmann V, Lohmann CP Vasoproliferative retinal tumors are benign tumors of unknown origin often accompanied by vitreoretinal inflammation. A 21-year-old female patient presented with acute reduced unilateral visual acuity. A solid yellow vascularized lesion was present in the inferior temporal retina accompanied by localized retinal detachment and accumulation of hard exudations. The only finding was an increased Bartonella henselae titer. Persistence of uveitis and blurred vision led to therapy for Bartonella henselae with macrolide antibiotics and successful tumor regression was achieved by cryotherapy. PMID: 21153829 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4289014 Wed, 15 Dec 2010 00:00:00 +0100 4289014 http://www.medworm.com/index.php?rid=4234539&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21125284%26dopt%3DAbstract We present five consecutive cases of our hospital from 2006 to 2009. METHOD: Retrospective analysis of all surgically treated patients with lacrimal duct diseases in the years 2006 to 2009, recording of malignant neoplasms and presentation of diagnostic and therapeutic approach. RESULTS: From January 2006 until October 2009 we performed 213 dacryocystorhinostomies at the Eye Clinic, Charité Campus Virchow Klinikum. In five patients intrasaccal malignancies were histologically proven by biopsy. None of the patients showed typical symptoms such as bloody epiphora. In two patients, a squamous cell carcinoma was seen, and one patient showed an adenocarcinoma. The other patients had a lymphoma and a malignant fibrous histiocytoma. The therapeutic approach consisted of surgical resection and ra... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4234539 Fri, 03 Dec 2010 00:00:00 +0100 4234539 http://www.medworm.com/index.php?rid=4208102&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21103877%26dopt%3DAbstract Authors: Ristau T, Kirchhof B, Liakopoulos S A 33-year-old woman presented with unilateral visual impairment since 2 months. A yellowish, prominent lesion was visible in the macula on funduscopy. Spectral domain OCT revealed a choroidal tumor with overlying subretinal fluid and subretinal hyperreflective material. Following a thorough examination including MRI, CT, coloscopy, bone scintigraphy, positron emission tomography and lymph node biopsy, the diagnosis of a choroidal granuloma with systemic sarcoidosis was made. After treatment with systemic steroids over 2 months the choroidal tumor flattened and visual acuity increased from 20/50 to 20/20. PMID: 21103877 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4208102 Sun, 21 Nov 2010 00:00:00 +0100 4208102 http://www.medworm.com/index.php?rid=4208101&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21103878%26dopt%3DAbstract Authors: Manousaridis K, Stropahl G, Guthoff RF A 53-year-old female patient presented with a palpable mass in the right medial orbit which had been present for 18 months. The left eye had been enucleated in childhood due to a perforating injury. An orbital biopsy performed ex domo showed unspecific inflammatory tissue but no definite diagnosis was made and systemic therapy with corticosteroids was unsuccessful. A second orbital biopsy was performed in our clinic and revealed a solitary fibrous tumor (SFT) of the orbit. Medial orbitotomy with tumor excision followed and the histological examination of the excised tumor established the diagnosis of SFT of the orbit with focal sarcomatous transformation. The patient presented 3 years later with a new orbital mass in a control MRI examina... Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4208101 Sun, 21 Nov 2010 00:00:00 +0100 4208101 http://www.medworm.com/index.php?rid=4208100&cid=s_36641_30_f&fid=36641&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21103879%26dopt%3DAbstract We report a case of acute myopic recurrence in a 38-year-old patient in a state of panic with a condition corresponding to LASIK 4 months earlier. The patient had commenced topiramate treatment 1 week previously, which is an antiepileptic drug also approved for migraine treatment. The symptoms were due to a rare topiramate-induced side effect (SE) with ciliochoroidal effusion, anterior shift of the lens-iris diaphragm and induced myopia. Cessation of topiramate led to complete remission of this idiosyncratic reaction, however, the patient's anxiety was impressive. Ocular administration of Topiramat-SE should thus be clarified. PMID: 21103879 [PubMed - as supplied by publisher] (Source: Der Ophthalmologe) Der Ophthalmologe journals http://www.medworm.com/rss/comments.php?id=4208100 Sun, 21 Nov 2010 00:00:00 +0100 4208100