MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Dermatol Online J' source. Wed, 08 Feb 2012 13:12:29 +0100 http://www.medworm.com/index.php?rid=5663225&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301038%26dopt%3DAbstract CONCLUSIONS: Applicants that list multiple unpublished manuscripts have a significant competitive advantage in matching into a dermatology residency, even if these manuscripts remain unpublished. PMID: 22301038 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663225 Mon, 06 Feb 2012 12:54:18 +0100 5663225 http://www.medworm.com/index.php?rid=5663224&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301039%26dopt%3DAbstract We describe a 39-year-old man with a long history of recurrent, tender, erythematous nodules in the axillary and anogenital regions, resulting in abscesses, sinus tract formation, and large areas of scarring. After 21 years of cutaneous disease with concurrent elevated systemic inflammatory markers, the patient was noted to have significant proteinuria. A kidney biopsy and immunostaining revealed deposits of amyloid A. Echocardiogram and electrocardiogram showed ventricular and atrial wall thickening with an appearance consistent with cardiac amyloid deposition. Systemic amyloid A amyloidosis is a serious, but rare, complication of chronic inflammatory disorders, including hidradenitis suppurativa, with potential multi-organ involvement including renal and cardiac manifestations. Amyloid A... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663224 Mon, 06 Feb 2012 12:54:18 +0100 5663224 http://www.medworm.com/index.php?rid=5663223&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301040%26dopt%3DAbstract We describe a patient with pemphigus foliaceus who developed two distinct disseminated cutaneous viral infections. Our patient is an 83-year-old female with a recent diagnosis of pemphigus foliaceus, who presented with painful ulcerations while on corticosteroids. Histopathology examination revealed disseminated herpes simplex virus (HSV). Despite adequate treatment with anti-herpetic treatment, some ulcerations failed to heal. A second biopsy revealed the presence of cytomegalovirus (CMV). This was treated successfully with appropriate antiviral therapy. In patients with autoimmune bullous disease, the development of new skin pain or new constitutional symptoms, change in primary morphology, rapid disease progression, or failure to respond to appropriate therapies should prompt the clinic... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663223 Mon, 06 Feb 2012 12:54:18 +0100 5663223 http://www.medworm.com/index.php?rid=5663222&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301041%26dopt%3DAbstract Authors: Antunes J, Pacheco D, Travassos R, Sequeira H, Filipe P, Marques MS Abstract A 29-year-old man, presented with multiple ulcers, nodules, abscesses, fistulae, and atrophic scars, over the right chest wall. Six years prior, the patient had a car accident, which resulted in skin loss of the right arm, shoulder, thoracic wall. In addition, he suffered a supracondylar fracture; orthopedic surgery and skin grafts were required. Material discharging from sinus tracts was obtained for mycological and bacteriological studies. Direct microscopic examination revealed small white grains. Cultures on Sabouraud and Lowenstein-Jensen media isolated orange-white colonies suggestive of Nocardia. PCR assay identified Nocardia nova. Thoracic and right upper limb CT showed signs of chronic os... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663222 Mon, 06 Feb 2012 12:54:18 +0100 5663222 http://www.medworm.com/index.php?rid=5663221&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301042%26dopt%3DAbstract Authors: Casamiquela KM, Cohen PR Abstract Radiation port dermatophytosis is the occurrence of tinea corporis within the area of radiation therapy delivery. A 68-year-old man, while receiving proton beam radiation for adenocarcinoma of the prostate, developed a dermatophyte infection in the area of the radiotherapy port. Including this patient, 4 patients with radiation port dermatophytosis have been reported in the world literature. The epidemiology, clinical manifestations, histopathology, diagnosis, pathogenesis, and treatment of this condition are discussed. The diagnosis of radiation port dermatophytosis may be missed because it is misinterpreted as radiation-induced dermatitis. Thus, it is possible that radiation port dermatophytosis may be more prevalent in patients receivin... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663221 Mon, 06 Feb 2012 12:54:18 +0100 5663221 http://www.medworm.com/index.php?rid=5663220&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301043%26dopt%3DAbstract We report a rare clinical presentation of HIV photodermatitis with widespread vitiligo-like depigmentation. PMID: 22301043 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663220 Mon, 06 Feb 2012 12:54:18 +0100 5663220 http://www.medworm.com/index.php?rid=5663219&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301044%26dopt%3DAbstract Authors: Ranawaka RR, de Silva N, Ragunathan RW Abstract Dermatophytic and non-dermatophytic onychomycosis (NDM) was indistinguishable clinically in our case series. Making a clinical diagnosis of onychomycosis without mycology is the routine practice in Sri Lanka. The prevalence of NDM (45.8%) was very high in our patient population, followed by yeasts (34.1%); dermatophyte infection made up only 20%. Therefore, the treatment of onychomycosis with griseofulvin seems futile. Close contact with soil, the habit of walking barefoot, frequent emersion of hands in water, and a hot, humid climate partly explain the variation in causative pathogens in this case series. PMID: 22301044 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663219 Mon, 06 Feb 2012 12:54:18 +0100 5663219 http://www.medworm.com/index.php?rid=5663218&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301045%26dopt%3DAbstract We report the case of a male child of 3 months with two different presentations of Langerhans cell-histiocytosis (LCH) at different times. The first presentation was classified as a self-healing LCH (formerly known as Hashimoto-Pritzker). The last presentation, although clinically suggestive of Letterer-Siwe (former designation), was not associated with systemic disease. This emphasizes that LCH cannot be compartmentalized into four groups, but considered a single disease with a wide spectrum of clinical presentations. This case underscores the importance of frequent and long-term follow-up of these patients. PMID: 22301045 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663218 Mon, 06 Feb 2012 12:54:18 +0100 5663218 http://www.medworm.com/index.php?rid=5663217&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301046%26dopt%3DAbstract We report a case of a young child with this rare disorder and explain the genetic cause. PMID: 22301046 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663217 Mon, 06 Feb 2012 12:54:18 +0100 5663217 http://www.medworm.com/index.php?rid=5663216&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301047%26dopt%3DAbstract Authors: Kumar P, Mondal AK, Ghosh K, Mondal A, Gharami RC, Chowdhury SN Abstract Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is a rare nonhereditary malformation of the eccrine duct. A relationship with linear porokeratosis is not yet established; some consider it as a rare variant of porokeratosis involving the acrosyringium, whereas others consider it a separate entity based on distinctive clinical features and histologic accentuation within ostial structures. A 7-year-old girl presented with multiple asymptomatic keratotic papules over her right palm, present since the age of 6 months. These papules were arranged in a linear distribution over the palm and middle finger of the right hand. Most of the papules were discrete. However, lesions on the middle finger co... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663216 Mon, 06 Feb 2012 12:54:18 +0100 5663216 http://www.medworm.com/index.php?rid=5663215&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301048%26dopt%3DAbstract CONCLUSIONS: On the basis of the similar studies reported in the literature and the large number of patients involved in our study, we can conclude that FT and GT can be clearly suggested as oral manifestations of plaque-type psoriasis, although the reason for this association is not clear. PMID: 22301048 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663215 Mon, 06 Feb 2012 12:54:18 +0100 5663215 http://www.medworm.com/index.php?rid=5663214&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301049%26dopt%3DAbstract Authors: Ueda M, Katoh M, Tanizaki H, Tanioka M, Matsumura Y, Miyachi Y Abstract Pyoderma gangrenosum (PG) is a rare, immune-mediated ulcerating skin disease. In up to 50 percent of the cases, PG is associated with underlying systemic disorders, most commonly inflammatory bowel diseases, connective tissue diseases, or hematological disorders. Herein, we present a case of refractory PG associated with ulcerative colitis (UC), successfully treated with infliximab. PMID: 22301049 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663214 Mon, 06 Feb 2012 12:54:18 +0100 5663214 http://www.medworm.com/index.php?rid=5663213&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301050%26dopt%3DAbstract Authors: Toya M, Tanioka M, Tanizaki H, Fujisawa A, Miyachi Y Abstract In recent years, sentinel lymph node (SLN) biopsy has been used as a diagnostic and prognostic indicator for a number of tumors, including malignant melanoma. Sentinel lymph node biopsy using combined dye-radiotracer technique improved the detection rate and made the method easier. However, many pitfalls on the SLN procedure have been reported. Herein, we present a new pitfall. A formation of scar and lymph node tissue was detected as a SLN 30 years after lymph node biopsy. PMID: 22301050 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663213 Mon, 06 Feb 2012 12:54:18 +0100 5663213 http://www.medworm.com/index.php?rid=5663212&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301051%26dopt%3DAbstract We report a case of very clinically prominent Mondor disease for which no precipitating etiology could be determined. PMID: 22301051 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663212 Mon, 06 Feb 2012 12:54:18 +0100 5663212 http://www.medworm.com/index.php?rid=5663211&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301052%26dopt%3DAbstract We report the 6th case of facial AF treated with topical rapamycin, 1 percent, once per day. An excellent response was achieved surprisingly rapidly. We propose this option as a safe and effective therapy. PMID: 22301052 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5663211 Mon, 06 Feb 2012 12:54:18 +0100 5663211 http://www.medworm.com/index.php?rid=5478646&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136857%26dopt%3DAbstract CONCLUSIONS: The fringe sign is a sensitive and specific clinical feature of traction alopecia when it involves the marginal hairline. PMID: 22136857 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478646 Wed, 07 Dec 2011 17:30:03 +0100 5478646 http://www.medworm.com/index.php?rid=5478645&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136858%26dopt%3DAbstract We describe the case of a 37-year-old male, with a diagnosis of psoriasis, who developed characteristic signs and symptoms of acute methotrexate toxicity after receiving an unknown amount of intravenous methotrexate. The patient experienced a distinct change in the morphology of his existing psoriatic plaques, which became ulcerated and necrotic in the week following the methotrexate injection. Shortly after the development of cutaneous erosions, the patient developed pancytopenia, which ultimately led to his death. Ulceration and necrosis of cutaneous psoriasis plaques may serve as a herald for the impending development of life-threatening pancytopenia in patients with acute methotrexate toxicity. PMID: 22136858 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478645 Wed, 07 Dec 2011 17:30:03 +0100 5478645 http://www.medworm.com/index.php?rid=5478644&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136859%26dopt%3DAbstract Authors: Demirci GT, Atıs G, Altunay IK Abstract Waardenburg Syndrome (WS) is a rare hereditary disorder that is characterized by the clinical manifestations of oculocutaneous anomalies of pigmentation, congenital deafness, dystopia canthorum, and broad nasal root. It demonstrates both genetically and clinically heterogenous characteristics. In this article, we report an 11-month-old boy with WS1, one of four clinicat types of WS. He exhibited white forelock, hypopigmented macules and patches, heterochromia irides, and dystopia canthorum. PMID: 22136859 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478644 Wed, 07 Dec 2011 17:30:03 +0100 5478644 http://www.medworm.com/index.php?rid=5478643&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136860%26dopt%3DAbstract We report a 33-year-old patient who developed calcinosis cutis at sites of nadroparin injections without any disturbance of calcium-phosphate product, PTH, or vitamin D. The pathogenesis of calcinosis cutis secondary to nadroparin injections remains controversial; Proposed causes included metastatic, dystrophic, iatrogenic, or multifactorial etiologies. This is the first case of multiple nodules of calcinosis cutis without alterations of calcium-phosphate product, PTH, or vitamin D, which supports an iatrogenic mechanism. We also suggest that calcinosis cutis could be more frequent than we thought and is probably an underdiagnosed entity. PMID: 22136860 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478643 Wed, 07 Dec 2011 17:30:03 +0100 5478643 http://www.medworm.com/index.php?rid=5478642&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136861%26dopt%3DAbstract We report a patient with cutaneous actinomycosis with multiple lesions without any detectable extra-cutaneous lesions. In our patient the actinomycosis was the presenting manifestation of HIV infection. PMID: 22136861 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478642 Wed, 07 Dec 2011 17:30:03 +0100 5478642 http://www.medworm.com/index.php?rid=5478641&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136862%26dopt%3DAbstract We present the case of a 54-year-old man with Sezary syndrome presenting with leonine facies, unresponsive to conventional therapies; he exhibited a promising response to subcutaneous low-dose alemtuzumab. PMID: 22136862 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478641 Wed, 07 Dec 2011 17:30:03 +0100 5478641 http://www.medworm.com/index.php?rid=5478640&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136863%26dopt%3DAbstract We report a case of APD in a patient with stage IV colon cancer with hepatic metastases. Although rare, APD associated with colon cancer is an important entity to consider; APD may be associated with a broader range of systemic diseases than previously recognized. PMID: 22136863 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478640 Wed, 07 Dec 2011 17:30:03 +0100 5478640 http://www.medworm.com/index.php?rid=5478639&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136864%26dopt%3DAbstract We describe a 12-year-old boy with typical manifestations: a hoarse voice, thick skin with yellowish papules, including the typical disposition on the margin of the eyelids, infiltration of the tongue and lips, and varicella-like scars. Histopathological examination revealed deposition of hyaline substance with PAS-positive diastase-resistance at the dermoepidermal junction and around vessels. Ultrastructural study showed considerable thickening of the basal lamina of vessels besides the intense deposition of amorphous material in the dermis. Genetic analysis was not available. PMID: 22136864 [PubMed - as supplied by publisher] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478639 Wed, 07 Dec 2011 17:30:03 +0100 5478639 http://www.medworm.com/index.php?rid=5478638&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136865%26dopt%3DAbstract Authors: Nath AK, Udayashankar C Abstract A 45-year-old man presented with a thickened and raised nail of his left fifth finger since birth. He was otherwise healthy. On examination, the nail of the left little finger was markedly thickened, hyperkeratotic, and situated at an angle of approximately 45 degrees to the long axis of the distal phalanx. There was prominent subungual hyperkeratosis. A diagnosis of congenital onychogryphosis of the little finger of idiopathic nature was considered. Visual analogy to the leaning tower of Pisa encouraged us to describe it as congenital leaning tower nail. PMID: 22136865 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478638 Wed, 07 Dec 2011 17:30:03 +0100 5478638 http://www.medworm.com/index.php?rid=5478637&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136866%26dopt%3DAbstract We report a case of disseminated histoplasmosis clinically mimicking secondary syphilis. PMID: 22136866 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478637 Wed, 07 Dec 2011 17:30:03 +0100 5478637 http://www.medworm.com/index.php?rid=5478636&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136867%26dopt%3DAbstract Authors: Cook E, Epstein R, Miller R Abstract Neutrophilic dermatosis of the hands is a rare localized variant of Sweet syndrome. The following is a case report of a 68-year-old man who presented to our clinic with progressive redness, swelling, and decreased mobility of the fingers. Examination revealed symmetric, violaceous, edematous, annular plaques and nodules on the dorsal and lateral surfaces of the thumb and index fingers. Biopsy demonstrated a dense neutrophilic infiltrate in the papillary dermis without evidence of vasculitis, changes consistent with Sweet syndrome. A thorough work up revealed no concurrently associated condition. Treatment with prednisone 10 mg daily, colchicine 0.6 mg twice daily, and pentoxifylline 400 mg three times daily resulted in significant impro... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478636 Wed, 07 Dec 2011 17:30:03 +0100 5478636 http://www.medworm.com/index.php?rid=5478635&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136868%26dopt%3DAbstract We report the case of a 60-year-old woman who presented with a 6-month history of a gradually enlarging solitary dark brown plaque in her right inguinal region. Histopathology showed hyperkeratosis with parakeratosis, acanthosis, disorganization of epidermal architecture, atypical keratinocytes, and increased melanin pigment of the papillary dermis. Considering the clinical and the histological evidence, a diagnosis of PBD was established. Complete resection confirmed the diagnosis. Pigmented Bowen disease is an unusual form of squamous carcinoma in situ. Other tumors in the differential diagnosis include pigmented basal cell carcinoma and superficial spreading melanoma. PMID: 22136868 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478635 Wed, 07 Dec 2011 17:30:03 +0100 5478635 http://www.medworm.com/index.php?rid=5478634&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136869%26dopt%3DAbstract Letter: Misdiagnosis of "neurofibromatosis" in patients with piebaldism. Dermatol Online J. 2011;17(11):13 Authors: Spritz R Abstract Miminal diagnostic criteria for the diagnosis of neurofibromatosis 1 (NF1) includes six or more café-au-lait macules plus axillary freckling. However, a recent report by Duarte et al claims co-occurrence of piebaldism and NF1 using this minimal criteria. We assert that this is not an accurate conclusion because both of these pigmentary findings occur frequently in typical cases of piebaldism. PMID: 22136869 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478634 Wed, 07 Dec 2011 17:30:03 +0100 5478634 http://www.medworm.com/index.php?rid=5478633&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136870%26dopt%3DAbstract We describe a case of pityriasis rubra pilaris refractory to conventional treatment, found to be associated with an unrecognized primary adenocarcinoma of the lung. Complete resolution of the eruption followed surgical resection of the tumor. PMID: 22136870 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478633 Wed, 07 Dec 2011 17:30:03 +0100 5478633 http://www.medworm.com/index.php?rid=5478632&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136871%26dopt%3DAbstract We report the case of a woman with the diagnosis of cutaneous mastocytosis mimicking multiple melanocytic nevi. Melanocytic stimulation can be induced by high levels of stem cell factor. The progressive increase in the number of pigmented lesions in a patient should lead us to perform a biopsy to search for mastocytosis. PMID: 22136871 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478632 Wed, 07 Dec 2011 17:30:03 +0100 5478632 http://www.medworm.com/index.php?rid=5478631&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22136872%26dopt%3DAbstract We report here a case of docetaxel-induced supravenous serpentine dermatitis with some interesting clinical and histological features. PMID: 22136872 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5478631 Wed, 07 Dec 2011 17:30:03 +0100 5478631 http://www.medworm.com/index.php?rid=5383197&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031627%26dopt%3DAbstract We report a case of extensive plaque-like masses on the scalp and face with no abnormalities in calcium or phosphate metabolism and no preceding inflammatory cutaneous conditions. With less than ten reported cases, to our knowledge, this is one the few cases of acquired plate-like osteoma cutis described in the literature. PMID: 22031627 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383197 Tue, 08 Nov 2011 04:35:03 +0100 5383197 http://www.medworm.com/index.php?rid=5383196&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031628%26dopt%3DAbstract We present an unusual case of localized, lenticular anetoderma in a man with HIV, a history of syphilis, and lichen planus. Both of these infections have been associated with anetoderma. Although his lesions are vaguely reminiscent of a variant of syphilitic anetoderma described in the 1930s, they are confined to a smaller anatomic distribution, differ in size, and have a papular appearance. As anetoderma can develop in the context of infectious disease, a diagnosis of anetoderma should trigger a thorough examination and evaluation for treatable concomitant illnesses. PMID: 22031628 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383196 Tue, 08 Nov 2011 04:35:03 +0100 5383196 http://www.medworm.com/index.php?rid=5383195&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031629%26dopt%3DAbstract Authors: Miller KK, Chu J, Patel R, Kamino H Abstract An 84-year-old woman presented with a three-month history of scaly, erythematous, annular papules and plaques on her chest, back, arms, and legs, which developed after a short course of doxycycline. Histopathologic examination of skin biopsy specimens was consistent with subacute cutaneous lupus erythematosus (SCLE). A presumptive diagnosis of drug-induced SCLE secondary to doxycycline was made. Although minocycline-induced SCLE is widely reported in the literature, there are no known previous case reports of doxycycline-induced SCLE. PMID: 22031629 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383195 Tue, 08 Nov 2011 04:35:03 +0100 5383195 http://www.medworm.com/index.php?rid=5383194&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031630%26dopt%3DAbstract We report the case of a 60-year-old man with penile-scrotal extramammary Paget disease (EMPD). The patient initially underwent Mohs micrographic surgery, but the margins remained positive after several sections; multiple scouting punch biopsies used to define the extent of the tumor were also positive. Because of concerns about functional impairment and cosmesis associated with wide local excision, the patient instead chose treatment with topical 5 percent imiquimod cream as a cytoreductive and margin-defining treatment. Owing to the association between EMPD and underlying malignant conditions, a thorough metastatic evaluation is necessary, particularly to rule out genitourinary cancer in the setting of penile-scrotal EMPD. Management of EMPD is complicated by the multifocal, non-contiguou... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383194 Tue, 08 Nov 2011 04:35:03 +0100 5383194 http://www.medworm.com/index.php?rid=5383193&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031631%26dopt%3DAbstract Authors: Berger E, Altiner A, Chu J, Patel R, Sanders S, Latkowski JA Abstract A 44-year-old African American woman presented with well-demarcated, pruritic and intermittently painful plaques and subsequently a diagnosis of mycosis fungoides stage IB was made. Six months after diagnosis, cutaneous tumors developed despite treatment with narrow-band ultraviolet B phototherapy. The patient failed low-dose methotrexate treatment and is now slowly improving on combination therapy with subcutaneous interferon alfa and oral bexarotene. This patient demonstrates the progression of patch/plaque stage disease to cutaneous tumors. Her case highlights the use of interferon and combination therapies in more advanced mycosis fungoides and demonstrates potential difficulties encountered in treat... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383193 Tue, 08 Nov 2011 04:35:03 +0100 5383193 http://www.medworm.com/index.php?rid=5383192&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031632%26dopt%3DAbstract Authors: Altiner A, Chu J, Patel R, Latkowski JA, Schaffer J, Sanders S Abstract A 46-year-old man presented to Bellevue Hospital Center with a widespread, erythematous, pruritic eruption that involved more than 80 percent of his body. The eruption started on his shoulder when he was in his 20s and, over the course of a one-year, spread to involve his face, trunk, and limbs. He was treated by various doctors in China and New York City with pills and creams with minimal benefit. He was not on any medications at the onset of the eruption and was working at a clothing manufacturing company. He has since filed for disability and does not currently work. A review of systems was negative for fevers, chills, arhtralgias, fatigue, weight-loss, worsening of eruption in the sun, enlargement ... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383192 Tue, 08 Nov 2011 04:35:03 +0100 5383192 http://www.medworm.com/index.php?rid=5383191&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031633%26dopt%3DAbstract We present a 31-year-old woman with a ten-year history of a progressive macular eruption; one of her macules demonstrated a wheal when rubbed. A biopsy was consistent with telangiectasia macularis eruptiva perstans. There were no signs and symptoms of systemic involvement despite the large body surface area of involvement. PMID: 22031633 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383191 Tue, 08 Nov 2011 04:35:03 +0100 5383191 http://www.medworm.com/index.php?rid=5383190&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031634%26dopt%3DAbstract We report a unique case of an ulcerated, segmental abortive hemangioma of the anogenital area with excellent clinical response to topical timolol gel. PMID: 22031634 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383190 Tue, 08 Nov 2011 04:35:03 +0100 5383190 http://www.medworm.com/index.php?rid=5383189&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031635%26dopt%3DAbstract Authors: Brauer JA, Anolik R, Tzu J, Meehan S, Lieber CD, Geronemus RG Abstract A 15-year-old boy with a diagnosis of generalized multiple glomangiomas was referred for evaluation and treatment of enlarging and increasingly painful lesions on his right ankle. The patient underwent a series of two treatments with long-pulsed KTP 1064 nm laser that resulted in substantial improvement in appearance and decreased pain. Generalized glomuvenous malformations, or multiple glomangiomas, are the less common presentation of proliferation of glomus cells and may have extracutaneous involvement. Whereas surgical management is often employed and definitive for solitary lesions, interventions such as laser therapy, may be beneficial for improvement of functional impairment and cosmesis as was ob... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383189 Tue, 08 Nov 2011 04:35:03 +0100 5383189 http://www.medworm.com/index.php?rid=5383188&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031636%26dopt%3DAbstract Authors: Mir A, Tlougan B, O'Reilly K, Tzu J, Meehan S, Kamino H, Franks AG Abstract The presence of lupus erythematosus with morphea in the same patient has rarely been reported. In this case, we describe a woman with the overlap of discoid lupus erythematosus with superficial morphea, diagnoses that are supported by histopathologic features and laboratory studies. PMID: 22031636 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383188 Tue, 08 Nov 2011 04:35:03 +0100 5383188 http://www.medworm.com/index.php?rid=5383187&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031637%26dopt%3DAbstract We report the case of a 63-year-old obese man with a rapid-onset of widespread acanthosis nigricans (AN) in the setting of having recently initiated treatment with niacin for dyslipidemia. Although obesity and insulin-resistance are risk factors for AN, AN associated with endocrine dysfunction tends to have a more gradual onset and limited involvement. Owing to our patient's age, the rapid onset, and extensive distribution of his eruption, we initially were concerned about paraneoplastic AN. However, an evaluation for a malignant condition was negative. The timing of the onset of our patient's eruption within several months of starting niacin therapy is consistent with niacin-induced AN. Niacin is known to cause rapidly progressive, widespread AN that is reversible upon discontinuation of ... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383187 Tue, 08 Nov 2011 04:35:03 +0100 5383187 http://www.medworm.com/index.php?rid=5383186&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031638%26dopt%3DAbstract We present a case of a 36-year-old man with multiple confluent, hypopigmented papules that coalesced into plaques with prominent follicular ostia over the dorsal aspects of the forearms, shoulders, upper chest, and upper back. Histologically there was selective loss of papillary dermal elastic fibers. The clinical and histopathologic findings in this case are consistent with an acquired disorder of elastic tissue which we believe represents the second reported case of papillary dermal elastosis. PMID: 22031638 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383186 Tue, 08 Nov 2011 04:35:03 +0100 5383186 http://www.medworm.com/index.php?rid=5383185&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031639%26dopt%3DAbstract Authors: Tran K, Hartman R, Tzu J, Meehan S, Sanders SE, Pomeranz MK, Sanchez M Abstract A 49-year-old man with advanced HIV/AIDS on anti-retroviral therapy (HAART) and trimethoprim-sulfamethoxazole (TMP-SMX) presented with a several-month history of pruritic, erythematous, lichenified papules that coalesced into hyperkeratotic plaques on the trunk and extremities in a sun-exposed distribution. He shortly thereafter developed a progressive depigmentation over more than 80 percent of his body surface area. A biopsy specimen of an erythematous plaque on the trunk showed a superficial and mid-dermal infiltrate of lymphocytes with eosinophils, most consistent with either chronic lichenoid drug eruption or atypical lymphoproliferative disorder (ACLD) of HIV. The patient's lichenoid skin... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383185 Tue, 08 Nov 2011 04:35:03 +0100 5383185 http://www.medworm.com/index.php?rid=5383184&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031640%26dopt%3DAbstract Authors: Brauer JA, Mundi J, Chu J, Patel R, Meehan S, Greenspan AH, Stein J Abstract A 58-year-old man presented for evaluation and treatment of non-tender, non-pruritic, annular patches on the right temple and frontal aspect of the scalp that reddened with exercise. A biopsy specimen showed a purpuric dermatitis with features of lymphocytic vasculitis; a diagnosis of exercise-induced progressive pigmentary purpura was made. Whereas progressive pigmentary purpura is purported to be caused by exercise, other similar appearing entities are associated with exercise, namely exercise-induced vasculitis (EIV). EIV may be considered as an acute microcirculatory deficiency and thermoregulation decompensation that occurs after episodes of exhaustive major muscular activity or after unusual... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5383184 Tue, 08 Nov 2011 04:35:03 +0100 5383184 http://www.medworm.com/index.php?rid=5363460&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031641%26dopt%3DAbstract We present a case of cheilitis granulomatosa (CG) as a manifestation of incomplete MRS. As the etiology remains unknown, treatment of CG is challenging. Intralesional glucocorticoids remain the first-line treatment, but recurrences are common. We discuss alternative treatment strategies that include combination therapy with other anti-inflammatory agents and biologics, such as infliximab. PMID: 22031641 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363460 Wed, 02 Nov 2011 03:40:04 +0100 5363460 http://www.medworm.com/index.php?rid=5363459&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031642%26dopt%3DAbstract We report a case of a 62-year-old woman who developed an asymptomatic, reticulated, gray-brown eruption on the dorsal aspects of the forearms of gradual onset that is clinically and histopathologically consistent with ABCD. Whereas the original report found an association between hypertension and/or the use of anti-hypertensive medications in the original cohort, we propose that this entity may, in fact, be associated more closely with cumulative sun damage and may be related to such acquired disorders of the skin as poikiloderma of Civatte. Treatment of these lesions may prove to be a challenge, with an emphasis on rigorous sun protection and adjunctive measures with depigmentating agents, chemical peels, and lasers. PMID: 22031642 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363459 Wed, 02 Nov 2011 03:40:04 +0100 5363459 http://www.medworm.com/index.php?rid=5363458&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031643%26dopt%3DAbstract Authors: Leger M, Newlove T, Chu J, Meehan S, Stein J Abstract A 79-year-old woman was admitted to our hospital with pustular pyoderma gangrenosum and an associated IgG kappa monoclonal gammopathy. The patient is currently being evaluated for possible multiple myeloma. IgG multiple myeloma and IgG monoclonal gammopathies are very rare in patients with pyoderma gangrenosum. The skin lesions are improving with the use of prednisone. PMID: 22031643 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363458 Wed, 02 Nov 2011 03:40:04 +0100 5363458 http://www.medworm.com/index.php?rid=5363457&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031644%26dopt%3DAbstract Authors: O'Reilly K, Chu J, Meehan S, Heller P, Ashinoff R, Gruson L Abstract A 58-year-old woman presented with a seven-year history of an eruption on her lower legs that was associated with edema, weeping, pruritus, and a burning sensation. Past medical history included Hashimoto thyroiditis, which was diagnosed eight years prior to presentation. Histopathologic examination was consistent with necrobiosis lipoidica (NL). To our knowledge, NL that is associated with Hashimoto thyroiditis has been described in only one prior report. NL is a chronic, cutaneous, granulomatous condition with degenerative connective-tissue changes of unknown etiology. Our patient responded well to a potent topical glucocorticoid and topical tretinoin. Although our patient did not have diabetes mellitus... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363457 Wed, 02 Nov 2011 03:40:04 +0100 5363457 http://www.medworm.com/index.php?rid=5363456&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031645%26dopt%3DAbstract Authors: Patel U, Chu J, Patel R, Meehan S Abstract Subcutaneous dematiaceous fungal infections, which include chromoblastomycosis and phaeohyphomycosis, are a heterogeneous group of clinical entities that are caused by dematiaceous or pigmented fungi found in soil. These infections have a wide spectrum of clinical presentations that depend largely on the specific causative organism and on the integrity of the host's immune response. Treatment is challenging and involves a highly individualized plan that often combines both surgical and long-term medical treatment. PMID: 22031645 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363456 Wed, 02 Nov 2011 03:40:04 +0100 5363456 http://www.medworm.com/index.php?rid=5363455&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031646%26dopt%3DAbstract We present a 60-year-old woman, who has a personal history of vulvar and cervical SCC and an appreciable disease burden from SCCs that involved five digits of her hands. PMID: 22031646 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363455 Wed, 02 Nov 2011 03:40:04 +0100 5363455 http://www.medworm.com/index.php?rid=5363454&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031647%26dopt%3DAbstract Authors: Warycha MA, Leger M, Tzu J, Kamino H, Stein J Abstract A 50-year-old man with hepatitis C virus infection and liver cirrhosis, who was awaiting transplantation, was admitted to the Transplant Surgery Service for treatment of a pleural effusion and an elevated ammonia level. Skin examination showed violaceous, firm nodules on the right thigh, which had been present for eight months. A fungal culture showed Trichophyton rubrum. The patient was started on itraconazole with improvement in the eruption. PMID: 22031647 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363454 Wed, 02 Nov 2011 03:40:04 +0100 5363454 http://www.medworm.com/index.php?rid=5363453&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031648%26dopt%3DAbstract Authors: Berger E, Hunt R, Tzu J, Patel R, Sanchez M Abstract A 36-year-old African man from Guinea with a history of albinism presented with a many-year history of scaling and erythema of the face, neck, and arms. The patient had light eyes, hair, and skin. Physical examination showed extensive photodamage. A skin biopsy specimen from the posterior aspect of the lower leg showed a squamous-cell carcinoma in situ. The most common types of oculocutaneous albinism (OCA), OCA 1 and OCA 2, are autosomal recessive disorders of pigmentation that commonly affect the skin, hair, eyes, and ears. Photodamage and skin cancers plague patients with albinism. In Africa, where albinism is prevalent, albinos face a myriad of social and medical issues. Skin cancer surveillance is an important consi... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363453 Wed, 02 Nov 2011 03:40:04 +0100 5363453 http://www.medworm.com/index.php?rid=5363452&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031649%26dopt%3DAbstract We present a patient with many classic features and review some of the treatment options available for these patients. PMID: 22031649 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363452 Wed, 02 Nov 2011 03:40:04 +0100 5363452 http://www.medworm.com/index.php?rid=5363451&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031650%26dopt%3DAbstract We present a unique case of alopecia associated with LET, which was partially responsive to hydroxychloroquine. We also note that the plaque of LET is adjacent to the plaque of discoid lupus erythematosus. PMID: 22031650 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363451 Wed, 02 Nov 2011 03:40:04 +0100 5363451 http://www.medworm.com/index.php?rid=5363450&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031651%26dopt%3DAbstract Authors: Adigun CG, Stein J Abstract A 59-year-old man presented for evaluation and excision of non-tender, fleshy nodules that were arranged in a dermatomal distribution from the left side of the chest to the left axilla. A biopsy specimen of a nodule was consistent with a neurofibroma. Owing to the lack of other cutaneous findings, the lack of a family history of neurofibromatosis, and the dermatomal distribution of the neurofibromas, this patient met the criteria for a diagnosis of segmental neurofibromatosis (SNF) according to Riccardi's definition of SNF and classification of neurofibromatosis. Because the patient has no complications of neurofibromatosis 1 no medical treatment is required. PMID: 22031651 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363450 Wed, 02 Nov 2011 03:40:04 +0100 5363450 http://www.medworm.com/index.php?rid=5363449&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031652%26dopt%3DAbstract We present a case of a 71-year-old man with erythroderma, who was ultimately diagnosed with severe, generalized LP. Treatment of severe LP is challenging, and there are few, robust, clinical trials in the literature to guide the selection of appropriate treatment. We discuss the treatment options for generalized LP and the evidence in support of these agents. PMID: 22031652 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363449 Wed, 02 Nov 2011 03:40:04 +0100 5363449 http://www.medworm.com/index.php?rid=5363448&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031653%26dopt%3DAbstract Authors: Marmon S, Chu J, Patel R, Meehan S, Pomeranz MK Abstract A 36-year-old man with a prior diagnosis of primary cutaneous marginal-zone B cell lymphoma presented with newly-developed, small, erythematous papules and nodules on his upper left arm and pink-to-skin-colored, clustered papules on his left forearm. A biopsy specimen and immunohistochemical analysis of the left arm lesions showed a lymphocytic infiltrate which stained positively for CD20 and Bcl-2 and negatively for CD10. A PET-CT scan was negative for any extra-cutaneous manifestations of disease. These clinicopathologic findings are indicative of recurrent localized primary cutaneous marginal-zone B cell lymphoma. PMID: 22031653 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363448 Wed, 02 Nov 2011 03:40:04 +0100 5363448 http://www.medworm.com/index.php?rid=5363447&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031654%26dopt%3DAbstract Authors: Miller K, Hunt R, Chu J, Meehan S, Stein J Abstract Erythema ab igne is a reticulated, erythematous or hyperpigmented dermatosis that results from chronic and repeated exposure to low levels of infrared radiation. Multiple heat sources have been reported to cause this condition, which include heated reclining chairs, heating pads, hot water bottles, car heaters, electric space heaters, and, more recently, laptop computers. Treatment consists of withdrawing the inciting heat source. Although erythema ab igne carries a good prognosis, it is not necessarily a self-limited diagnosis as patients are at long-term risk of developing subsequent cutaneous malignant conditions, which include squamous cell and merkel-cell carcinomas. PMID: 22031654 [PubMed - in process] (Source: ... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363447 Wed, 02 Nov 2011 03:40:04 +0100 5363447 http://www.medworm.com/index.php?rid=5363446&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031655%26dopt%3DAbstract We present a case of chemical leukoderma secondary to pyrethroid insecticides that has progressed despite avoidance of the agent for over ten years. PMID: 22031655 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363446 Wed, 02 Nov 2011 03:40:04 +0100 5363446 http://www.medworm.com/index.php?rid=5363445&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22031656%26dopt%3DAbstract We present a patient with lichen planopilaris, lichen planus pigmentosus, and nonscarring alopecia of the genitals, who is reminiscent of GLPLS. Recent work shows evidence for autoimmunity in GLPLS. Further elucidation of underlying mechanisms can improve categorization and treatment options in this rare and controversial syndrome. PMID: 22031656 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5363445 Wed, 02 Nov 2011 03:40:04 +0100 5363445 http://www.medworm.com/index.php?rid=5301926&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971266%26dopt%3DAbstract Authors: Raimer DW, Group AR, Petitt MS, Nosrati N, Yamazaki ML, Davis NA, Kelly BC, Gibson BR, Montilla RD, Wagner RF Abstract Cadaveric allografts and a large variety of other biologic dressings have been reported as being useful for the postoperative management of Mohs micrographic surgery (MMS) wounds. Although the use of porcine xenografts for the immediate postoperative management of these wounds is known, their use has not been detailed in the dermatology literature. A case series of 15 consecutive Mohs micrographic surgery patients (mean age = 74.9 years, range = 49 to 89 years) with wounds initially managed with porcine xenografts is described. Porcine xenografts were useful in a variety of clinical settings following MMS. These included: 1. wound management when tumor mar... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301926 Mon, 10 Oct 2011 11:40:02 +0100 5301926 http://www.medworm.com/index.php?rid=5301925&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971267%26dopt%3DAbstract Authors: Okazaki C, Wakusawa C, Chikama R, Murakami K, Hitomi H, Satoh K, Makimura K, Hiruma M Abstract A 76-year-old woman farmer with a 20-year history of oral steroid treatment for polyarteritis nodosa, noted a rash consisting of numerous small papules on the dorsum of her right hand in February 2007. The rash worsened over time, and in April 2008 red papules and pustules as big as grains of rice fused to form plaques extending up her arm from the dorsum of the right hand to the extensor surface of the forearm. The plaques were accompanied by erosions, ulcers, and crusts. Skin biopsy specimens from the dorsum of the right hand showed a dense cell infiltration in the upper to middle layer of the dermis, with numerous morula-like microorganisms within the cells. Cultures of the sp... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301925 Mon, 10 Oct 2011 11:40:02 +0100 5301925 http://www.medworm.com/index.php?rid=5301924&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971268%26dopt%3DAbstract Authors: Onofiok E, Sivamani RK, Barr KL Abstract Calciphylaxis is a rare but life-threatening disease characterized by deposition of calcium within small and medium sized vessels, with subsequent thrombosis, cutaneous ischemia, and necrosis. Because of its systemic nature, calciphylaxis is typically a symmetrical, bilaterally-distributed phenomenon. Here, we present an unusual case of unilateral leg calciphylaxis in the setting of relative chronic arterial insufficiency of the affected extremity secondary to steal syndrome. PMID: 21971268 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301924 Mon, 10 Oct 2011 11:40:02 +0100 5301924 http://www.medworm.com/index.php?rid=5301923&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971269%26dopt%3DAbstract CONCLUSION: The working-theory of a reactive etiology for this condition might explain the evolution in appearance following initiation of HAART. The presence of papules with a dusky targetoid center suggests that this condition should be considered in the differential diagnosis with syphilis or atypical erythema multiforme in HIV patients. PMID: 21971269 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301923 Mon, 10 Oct 2011 11:40:02 +0100 5301923 http://www.medworm.com/index.php?rid=5301922&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971270%26dopt%3DAbstract Authors: Watarai A, Amoh Y, Aki R, Takasu H, Katsuoka K Abstract A 46-year-old man noticed a nodule on his sole. The nodule was removed and the specimen showed a lobular proliferation of tumor cells with glandular differentiation embedded in mucinous stroma. A diagnosis of chondroid syringoma was made. Twelve years later, he noted a swelling in the right inguinal region. The mass was surgically removed. The histopathological findings of the lymph node showed the more atypical tumor cells in the mucoid stroma. Upon reexamination, the primary tumor contained malignant chondroid syringoma (MCS) cells; the tumor cells metastasized to lymph node. MCS is rare with 43 reported cases in the literature. The site of the primary tumor was the lower extremity in 35 percent, the head in 28 perc... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301922 Mon, 10 Oct 2011 11:40:02 +0100 5301922 http://www.medworm.com/index.php?rid=5301921&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971271%26dopt%3DAbstract Authors: Cruz MJ, Baudrier T, Azevedo F Abstract Chronic wounds of the lower limbs are a major public healthcare problem affecting 1 percent of the adult population and 3 to 5 percent of people older than 65 years. These numbers are rising in the western population as a result of increased life expectancy and increased risk factors for atherosclerotic occlusion, such as smoking, obesity, and diabetes mellitus. This very debilitating condition, which reduces significantly the quality of life, causes social discomfort and generates considerable cost, not only to the patient but also to the society. Treating chronic leg ulcers is always a challenge. Over the last years, the treatment of this condition has been given more attention because of the frequent ineffectiveness of the methods... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301921 Mon, 10 Oct 2011 11:40:02 +0100 5301921 http://www.medworm.com/index.php?rid=5301920&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971272%26dopt%3DAbstract Authors: Rosman IS, Nunley KS, Lu D Abstract A 53-year-old man presented with a recurrent pruritic eruption accompanied by oral sores. His past medical history was significant for subclinical B-cell chronic lymphocytic leukemia (CLL), which had never been treated. On exam, there were erythematous papules and plaques studded with vesicles on the neck, trunk, and upper extremities. Two skin biopsies showed common features of a perivascular and periadnexal lymphocytic infiltrate in the superficial to mid-dermis. Immunohistochemical staining of the lymphocytes showed co-expression of CD20, CD23, CD5, and CD43, consistent with a diagnosis of cutaneous involvement by the patient's CLL. This case highlights the importance of considering leukemia cutis in patients with underlying CLL prese... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301920 Mon, 10 Oct 2011 11:40:02 +0100 5301920 http://www.medworm.com/index.php?rid=5301919&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971273%26dopt%3DAbstract We report the case of a 20-year-old male presenting with a round, erythematous, atrophic plaque on the midline of the anterior aspect of the neck. The lesion was asymptomatic and was stable since birth. A skin biopsy was performed. Histological examination showed a band like hypocellular fibrotic area in the superficial reticular dermis, which did not spread to subcutaneous tissue. The cells were CD34-positive and S100 and CD56-negative. Elastic fibers were present. Altogether the morphological and immunostaining features were neither suggestive of dermatofibrosarcoma protuberans nor neurofibroma. Thus, the pathological findings were consistent with MLDDH. Clinical differential diagnosis includes anetoderma, aplasia cutis, or atrophic DFSP. Histological differential was made with atrophic ... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301919 Mon, 10 Oct 2011 11:40:02 +0100 5301919 http://www.medworm.com/index.php?rid=5301918&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971274%26dopt%3DAbstract Authors: Antunes J, Pacheco D, Travassos R, Filipe P Abstract Cutaneous infiltration by leukemic cells is uncommon and may be associated with progression of disease. The authors present the case of a 77-year-old female patient, referred to the dermatology clinic for red, erythematous, pruritic papules, which had suddenly appeared on her left hemithorax, along the C6 dermatome, with a 4-week duration. She had already been medicated with Valacyclovir and Acyclovir for 4 weeks, without clinical improvement. She also had a diagnosis of B-cell chronic lymphocytic leukemia (B-CLL), type 2 diabetes mellitus, and multinodular goiter. Tzanck smear showed no multinucleated giant cells,and PCR testing for Varicella Zoster Virus (VZV) and Herpes Simplex Virus (HSV) on skin biopsy was negative.... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301918 Mon, 10 Oct 2011 11:40:02 +0100 5301918 http://www.medworm.com/index.php?rid=5301917&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971275%26dopt%3DAbstract We describe a 12-year-old girl with characteristic lesions of PEODDN and describe her response to treatment with a combination CO2/Erbium laser. We also briefly review the literature on PEODDN. PMID: 21971275 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301917 Mon, 10 Oct 2011 11:40:02 +0100 5301917 http://www.medworm.com/index.php?rid=5301916&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971276%26dopt%3DAbstract We report here a case of linear, unilateral, verrucous plaques on the leg of a young man, diagnosed as ACN. PMID: 21971276 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301916 Mon, 10 Oct 2011 11:40:02 +0100 5301916 http://www.medworm.com/index.php?rid=5301915&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971277%26dopt%3DAbstract We describe a classical case of subungual GT and discuss its presentation, diagnosis, management, as well as "atypical" or "malignant" variants. PMID: 21971277 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301915 Mon, 10 Oct 2011 11:40:02 +0100 5301915 http://www.medworm.com/index.php?rid=5301914&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971278%26dopt%3DAbstract Authors: Mascarenhas R, Guiote V, Agro J, Henrique M Abstract A 5-month-old boy was observed in our department presenting with an ulcerated infantile hemangioma on the right buttock. This lesion appeared during the first week of life and had been growing progressively, showing ulceration for 3 weeks. We started treatment with corticosteroids, first with the association of betametasone and fusidic acid topically, and then systemically. After 6 weeks of oral treatment as there was no significant improvement, corticosteroid therapy was slowly tapered and local application of imiquimod 5 percent cream, on alternate days, was started. After 12 weeks of therapy with imiquimod there was complete resolution of the ulceration. There were no side effects. PMID: 21971278 [PubMed - in proc... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301914 Mon, 10 Oct 2011 11:40:02 +0100 5301914 http://www.medworm.com/index.php?rid=5301911&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971279%26dopt%3DAbstract Authors: Grillo E, Vano-Galvan S, Gonzalez C, Pedro J Abstract Neutrophilic eccrine hidradenitis (NEH) was originally described as a distinctive dermatosis occurring in patients undergoing chemotherapy, especially associated with the use of cytarabine in the treatment of acute myelogenous leukemia (AML). This disorder is characterized by a neutrophilic infiltrate around the eccrine glands and coils and is associated with necrosis. However, atypical findings in the histology have been reported. To the best of our knowledge, leukocytoclastic vasculitis has not been described in association with NEH. We hypothesize that a toxic effect of cytarabine may damage the vessel wall to some extent, causing a vasculitic phenomenon. PMID: 21971279 [PubMed - in process] (Source: Dermatol Onl... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301911 Mon, 10 Oct 2011 11:40:02 +0100 5301911 http://www.medworm.com/index.php?rid=5301900&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971280%26dopt%3DAbstract We report two patients that developed cutaneous and histologic changes consistent with psoriasis while receiving treatment with adalimumab for inflammatory arthridities: one patient with Crohn disease and ankylosing spondylitis who tolerated adalimumab for 15 months before developing psoriasis and another patient with rheumatoid arthritis who developed psoriasis 3 years after starting adalimumab. Both patients experienced rapid resolution of their psoriasis after discontinuation of adalimumab. PMID: 21971280 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5301900 Mon, 10 Oct 2011 11:40:02 +0100 5301900 http://www.medworm.com/index.php?rid=5249640&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635833%26dopt%3DAbstract Authors: Morrison LK, Lopez IE Abstract Yellow plaques and papules on the skin are hallmarks of xanthomas. These are not always associated with abnormalities in lipid profiles or their associated proteins. In cases of diffuse normolipemic plane xanthomas these cutaneous findings are often associated with myelodyscrasias including monoclonal gammopathy of unknown significance and multiple myeloma. Such clinical presentations may indicate that an evaluation for myelodyscrasias is warranted. PMID: 21635833 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5249640 Sat, 24 Sep 2011 19:16:02 +0100 5249640 http://www.medworm.com/index.php?rid=5249639&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635834%26dopt%3DAbstract We describe a 12-year-old girl affected by Down syndrome who presented a localized form of EPS, which involved only the extremities. Strangely, it resolved spontaneously after biopsy with no recurrence, without therapy. PMID: 21635834 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5249639 Sat, 24 Sep 2011 19:16:02 +0100 5249639 http://www.medworm.com/index.php?rid=5221447&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549086%26dopt%3DAbstract We present a case of MLC in which the cutaneous affectation was the first sign of the systemic leukemia. In this setting, the myeloperoxidase stain was the clue to rule out the possibility of HSS. We discuss the role and the utility of the myeloperoxidase stain in the differentiation of these two entities. PMID: 21549086 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221447 Thu, 15 Sep 2011 21:44:02 +0100 5221447 http://www.medworm.com/index.php?rid=5221446&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906481%26dopt%3DAbstract We present a case of Kabuki syndrome in a 6-year-old boy who, in addition to the various features typical of the disease, also exhibited a Becker nevus - a condition not previously associated with this syndrome. The usefulness of dermoscopy in studying alterations in the dermatoglyphic patterns is also discussed. PMID: 21906481 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221446 Thu, 15 Sep 2011 21:44:02 +0100 5221446 http://www.medworm.com/index.php?rid=5221445&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906482%26dopt%3DAbstract Authors: Lehmer LM, Ragsdale BD Abstract Dermatofibroma (DF), also referred to as cutaneous fibrous histiocytoma (CFH), is a common tumor of the skin presenting as a firm nodule located predominantly on the limbs and shoulder and pelvic girdles that often extends into superficial subcutaneous tissue. This is a retrospective study of 26 DFs located on digits. All case slides were retrieved from saved files for diagnostic verification. One case was rejected after revision of the diagnosis to giant cell tumor of the tendon sheath. The 26 remaining cases constitute this reported series. Digital DFs affected 27 to 70 year-olds in a 2.25:1 male to female ratio. The most common clinical diagnosis submitted was "growth" or wart. In only 6 out of the 26 cases was the pre-biopsy diagnosis of... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221445 Thu, 15 Sep 2011 21:44:02 +0100 5221445 http://www.medworm.com/index.php?rid=5221444&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906483%26dopt%3DAbstract We report a case of a 44-year-old man born and raised in North America who presented with total skin discoloration since birth. PMID: 21906483 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221444 Thu, 15 Sep 2011 21:44:02 +0100 5221444 http://www.medworm.com/index.php?rid=5221443&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906484%26dopt%3DAbstract Authors: Lopes C, Duarte AF, Correia O, Delgado L Abstract The prevalence of atopic dermatitis is increasing in western societies and this disease has a significant effect on the quality of life of patients and their families. The pathophysiology is complex, but there are recent insights on innate and adaptive immunity dysfunction in this condition that increases the predisposition to colonization/infection with characteristic types of microorganisms. We provide an up-to-date review of the pathophysiology of atopic dermatitis, highlighting the clinical implications of skin barrier dysfunction and immunological deregulation. We suggest a useful approach for handling exacerbations and infectious events. PMID: 21906484 [PubMed - as supplied by publisher] (Source: Dermatol Online J... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221443 Thu, 15 Sep 2011 21:44:02 +0100 5221443 http://www.medworm.com/index.php?rid=5221442&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906485%26dopt%3DAbstract We present a patient with an unusual linear form. PMID: 21906485 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221442 Thu, 15 Sep 2011 21:44:02 +0100 5221442 http://www.medworm.com/index.php?rid=5221441&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906486%26dopt%3DAbstract Authors: Scheinfeld N Abstract Magro et al in April of 2011 published a new article in the American Journal of Clinical Pathology on the etiology and treatment of Degos Disease (DD), and importantly, its fatal variant malignant atrophic papulosis (MAP). Specifically, Magro noted that MAP is a disease involving the complement cascade that can be treated effectively with eculizumab. DD has two variants, a benign variant confined to the skin and a malignant (heretofore fatal) variant that involves the skin and systemic organs. Five aspects of DD are discussed: (1) the clinical findings of DD, (2) thrombosis and DD, (3) the histology of DD, (4) the presence of viral like inclusions in the endothelial cells of patients with DD, and (5) the lack of any apparent immune defect that relates... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221441 Thu, 15 Sep 2011 21:44:02 +0100 5221441 http://www.medworm.com/index.php?rid=5221440&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906487%26dopt%3DAbstract We report a 42-year-old woman with a 2 year history of asymptomatic yellow papules on the vulva that were proven to be syringomas by histopathologic examination. PMID: 21906487 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221440 Thu, 15 Sep 2011 21:44:02 +0100 5221440 http://www.medworm.com/index.php?rid=5221439&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906488%26dopt%3DAbstract We report a case of genital primary herpetic infection in a 5-month-old male, exclusively breastfed, whose mother suffered from active labial herpes. PMID: 21906488 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221439 Thu, 15 Sep 2011 21:44:02 +0100 5221439 http://www.medworm.com/index.php?rid=5221438&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906489%26dopt%3DAbstract We present a dermal melanocytosis with superimposed nevus spilus on the arm of a 5-year-old boy. We recently introduced a new type of phacomatosis, which we termed "phacomatosis pigmentopigmentalis," that is analogous to phacomatosis pigmentokeratotica or pigmentovascularis, for describing the association of two pigmented nevi. The present case is an example of this type of phacomatosis, which now we prefer to define phacomatosis pigmento-pigmentaria according to the correct Latin terminology. PMID: 21906489 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221438 Thu, 15 Sep 2011 21:44:02 +0100 5221438 http://www.medworm.com/index.php?rid=5221437&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906490%26dopt%3DAbstract Authors: Ferreira O, Osório F, Lisboa C, Silva MJ, Eloy C, Paiva ME, Azevedo F Abstract A 76-year-old male patient with an angioimmunoblastic T-cell lymphoma under treatment with fludarabine was referred because of scrotal ulcers, evolving for several months. Respiratory, gastrointestinal, and urinary symptoms were denied. Histopathological examination showed the presence of a chronic inflammatory process with epithelioid granulomas. Ziehl-Neelsen stain was positive for acid-fast bacilli. PCR analysis allowed the identification of a mycobacteria strain belonging to the Mycobaterium tuberculosis complex. Skin biopsy was repeated and culture revealed M. tuberculosis sensitive to traditional tuberculostatic drugs. This bacteria was also isolated in bronchial and urinary specimens. Al... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221437 Thu, 15 Sep 2011 21:44:02 +0100 5221437 http://www.medworm.com/index.php?rid=5221436&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906491%26dopt%3DAbstract Authors: Lim CS, Lim SL Abstract Rapid confirmation of dermatomycoses is desirable because it allows the clinician to initiate appropriate therapy without delay. The routine potassium hydroxide (KOH) wet-mount is cheap and rapid to use but this method lacks a color contrast. We offer a simple practical tip of adding Chicago Sky Blue (CSB) stain to KOH to highlight fungal elements and provide a color contrast that makes reading and interpretation simple, even for the novice. PMID: 21906491 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221436 Thu, 15 Sep 2011 21:44:02 +0100 5221436 http://www.medworm.com/index.php?rid=5221435&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906492%26dopt%3DAbstract Authors: Manganoni AM, Zane C, Pavoni L, Farisoglio C, Sereni E, Calzavara-Pinton P Abstract Herein we report a case of a melanoma arising in a patient receiving adalimumab and methotrexate for rheumatoid arthritis. A limited number of studies reported melanoma growth in patients undergoing treatment with biologics. This case report with a brief review of literature suggests that patients under treatment with biologics should be counseled to identify new pigmented lesions or changes in preexisting nevi. Clinicians' collaboration will facilitate recognition and timely diagnosis of early melanoma. If there is any doubt, excision for histological evaluation should be considered. Pending new studies, careful observation is encouraged. PMID: 21906492 [PubMed - in process] (Source: D... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221435 Thu, 15 Sep 2011 21:44:02 +0100 5221435 http://www.medworm.com/index.php?rid=5221434&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906493%26dopt%3DAbstract We report the case of a 63-year-old woman with an underlying colon cancer who presented with a pigmented lesion in the midline of the abdomen above the umbilicus. Immunohistochemical stains demonstrated the lesion to be CK7+/CK20- as well as negative for melanocytic markers (S100, MiTF, Melan-A, HMB-45). Further, the immunophenotype of the EMPD differed from the patient's underlying colon adenocarcinoma (CK20+/CK7-), arguing against an ectopic focus of her established disease. Making the distinction between pigmented EMPD and melanoma is a potential diagnostic pitfall because of the histologic similarities. Extramammary Paget disease should be considered in the morphologic differential diagnosis of melanoma and, if necessary, supporting studies should performed to aid in this distinction. ... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221434 Thu, 15 Sep 2011 21:44:02 +0100 5221434 http://www.medworm.com/index.php?rid=5221433&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906494%26dopt%3DAbstract Authors: Zhang KS, Modi GM, Hsu S Abstract Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome or drug-induced hypersensitivity is a potentially life-threatening drug hypersensitivity syndrome most commonly associated with anticonvulsants, allopurinol, long-acting sulfonamides, dapsone, and minocycline. In the setting of HIV infection, the antiretroviral medicines abacavir, nevirapine, and efavirenz have all shown well-documented associations with DRESS syndrome. There has only been one case (in a poster presentation) of this syndrome in a patient who was taking raltegravir. PMID: 21906494 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221433 Thu, 15 Sep 2011 21:44:02 +0100 5221433 http://www.medworm.com/index.php?rid=5221432&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21906495%26dopt%3DAbstract This report discusses Haim and Haim-Munk syndrome. PMID: 21906495 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5221432 Thu, 15 Sep 2011 21:44:02 +0100 5221432 http://www.medworm.com/index.php?rid=5142651&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21830347%26dopt%3DAbstract Authors: Goihman M PMID: 21830347 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5142651 Sat, 20 Aug 2011 10:30:03 +0100 5142651 http://www.medworm.com/index.php?rid=5110561&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810386%26dopt%3DAbstract We report a patient with the sporadic form of the disease who developed pigmented macules in the rarely involved sites of the lower back and vulva. Her vulvar lesions were treated with Er:YAG laser ablation. PMID: 21810386 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110561 Wed, 10 Aug 2011 18:30:03 +0100 5110561 http://www.medworm.com/index.php?rid=5110560&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810387%26dopt%3DAbstract We report a case series of patients with hypergranulation tissue on the scalp who were successfully treated with a 595 nm pulsed dye laser and hydrocolloid dressing. PMID: 21810387 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110560 Wed, 10 Aug 2011 18:30:03 +0100 5110560 http://www.medworm.com/index.php?rid=5110559&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810388%26dopt%3DAbstract We report an unusual presentation of PC-ALCL. A 90-year-old, uncircumcised male presented with a 3-week history of painful penile swelling and discharge. The patient was treated with cephalexin and underwent emergent circumcision for paraphimosis. The diagnosis of ALCL was made on microscopic evaluation of the foreskin along with follow-up staging studies. A literature review revealed 31 previously reported cases of penile lymphoma, one of which reported a primary penile CD30+ T-cell lymphoma similar to ours. Only one case report described a lymphoma presenting as paraphimosis. Our case is the second reported case of PC-ALCL of the penis and the first of its kind to present as paraphimosis. Lymphomas must be included in the differential diagnosis of penile lesions and paraphimosis. When pr... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110559 Wed, 10 Aug 2011 18:30:03 +0100 5110559 http://www.medworm.com/index.php?rid=5110558&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810389%26dopt%3DAbstract We report the case of a 35-year-old woman with active TAO, refractory to smoking cessation and conventional therapy, who exhibited a favorable clinical response to treatment with bosentan, an oral dual endothelin receptor antagonist, administered on a compassionate-use basis. Six months after starting bosentan therapy, the pain and trophic lesions in the patient's toes had completely disappeared. Bosentan was well tolerated, without any observed adverse reaction. The findings of this case report suggest that bosentan may be considered a therapeutic option for patients with active disease, despite quitting smoking, or for those who fail in absolute abstention from smoking. PMID: 21810389 [PubMed - as supplied by publisher] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110558 Wed, 10 Aug 2011 18:30:03 +0100 5110558 http://www.medworm.com/index.php?rid=5110557&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810390%26dopt%3DAbstract We present herein a new case of spontaneous cutaneous endometriosis of the umbilicus that was studied immunohistochemically and review the salient clinicopathologic features of this rare condition. PMID: 21810390 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110557 Wed, 10 Aug 2011 18:30:03 +0100 5110557 http://www.medworm.com/index.php?rid=5110556&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810391%26dopt%3DAbstract Authors: Kumar S, Mahajan BB, Singh R Dyschromatosis universalis hereditaria is an infrequently occurring genodermatosis with peculiar pigmentary changes, consisting of varying sized, intermingled hyperpigmented and hypopigmented macules that give an overall impression of mottling. We hereby report a case of dyschromatosis universalis hereditaria in a young female with a family history of the disorder. PMID: 21810391 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110556 Wed, 10 Aug 2011 18:30:03 +0100 5110556 http://www.medworm.com/index.php?rid=5110555&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810392%26dopt%3DAbstract We report a new case of EED in a 58-year-old man who presented with a three-month history of plaques and nodules on the extensor surfaces of hands, elbows, knees, ankles, forearms, and buttocks. Histology showed a leucocytoclastic vasculitis, suggestive of the diagnosis of EED. Screening for an associated pathology, namely a paraproteinemia or a solid cancer, was negative. Treatment with dapsone leads to amelioration within few weeks. PMID: 21810392 [PubMed - as supplied by publisher] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110555 Wed, 10 Aug 2011 18:30:03 +0100 5110555 http://www.medworm.com/index.php?rid=5110554&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810393%26dopt%3DAbstract Authors: Kim DP, Klein PA Cutis laxa (CL) is a rare connective tissue disorder characterized by loosely hanging skin folds. Histopathology reveals degenerative changes in the dermal elastic fibers, although loss of elastin can also occur in alveolar walls, blood vessels, and other organs. The coexistence of autoimmune diseases and monoclonal gammopathies is rare but well documented in the literature. Here we report an unusual case of cutis laxa (CL) preceding the development of serologic evidence of systemic lupus erythematosus (SLE) and a diagnosis of multiple myeloma (MM) by seven and eleven years respectively. PMID: 21810393 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110554 Wed, 10 Aug 2011 18:30:03 +0100 5110554 http://www.medworm.com/index.php?rid=5110553&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810394%26dopt%3DAbstract Authors: Stephens JB, Raimer SS, Wagner RF Acting internships are an important component of modern day medical school curriculum. Several specialties outside of internal medicine now offer acting internship experiences to fourth year medical students. We have found that a dermatology acting internship is a valuable experience for fourth year medical students who are interested in pursuing a residency in dermatology. Our experience with the dermatology acting internship over the 2010-2011 academic year is described. PMID: 21810394 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110553 Wed, 10 Aug 2011 18:30:03 +0100 5110553 http://www.medworm.com/index.php?rid=5110552&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810395%26dopt%3DAbstract Authors: Ueno M, Yamamoto T, Yamanaka M, Matsunaga T A 43-year-old Japanese man with alcoholic liver cirrhosis developed a nodule on the face 1 year prior to presentation. Histopathological examination showed amyloid deposition in the entire dermis, with numerous plasma cells. Nodular primary localized cutaneous amyloidosis is a rare form of amyloidosis, which needs long-term follow-up because of the possibility of the development of systemic amyloidosis. Also, this type of cutaneous amyloidosis may have other complications. PMID: 21810395 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110552 Wed, 10 Aug 2011 18:30:03 +0100 5110552 http://www.medworm.com/index.php?rid=5110551&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810396%26dopt%3DAbstract Authors: Farshi S, Mansouri P An eight-year-old child presented with generalized popular eruptions of two years duration. The diagnosis was lichen nitidus with pathologic confirmation. The lesions were successfully reduced and flattened by pimecrolimus 1 percent cream for 8 weeks. PMID: 21810396 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110551 Wed, 10 Aug 2011 18:30:03 +0100 5110551 http://www.medworm.com/index.php?rid=5110550&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810397%26dopt%3DAbstract Authors: Menezes N, Rita G, Inês L, Paulo V, Armando B Collision tumor is a term used to refer to the association of various types of tumors in time and space. Despite most of them not being clinically relevant, sometimes there is a union between a benign lesion and a malignant one. The clinical diagnosis in these cases is usually extremely difficult, particularly if one of the lesions is pigmented. Dermoscopy and confocal microscopy are noninvasive diagnostic methods that make possible the visualization of morphologic structures not visible to the naked eye, thus making diagnosis of these lesions possible. Here we describe a case in which the corrected diagnosis of a collision between a seborrheic keratosis and a basal cell carcinoma was only possible by means of confocal microscopy... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110550 Wed, 10 Aug 2011 18:30:03 +0100 5110550 http://www.medworm.com/index.php?rid=5110549&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810398%26dopt%3DAbstract We present a case of EMPD in an unusual location (periumbilical skin). This was treated with fresh MMS, but reappeared, necessitating a second MMS (slow). PMID: 21810398 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110549 Wed, 10 Aug 2011 18:30:03 +0100 5110549 http://www.medworm.com/index.php?rid=5110548&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21810399%26dopt%3DAbstract Authors: Jaka A, López-Pestaña A, Tuneu A, Lobo C, López-Núñez M, Ormaechea N Diltiazem is a calcium channel blocking agent used for the treatment of hypertension. Cutaneous adverse effects are uncommon. The most frequently reported are itching, urticaria, and maculopapular eruption. A peculiar, cutaneous photodistributed reticulated hyperpigmentation secondary to diltiazem has been recently reported. A 66-year-old white woman with a 2 year history of pruritic hyperpigmented lesions on her face was seen in the clinic. Past medical history was remarkable for hypertension, which had been treated with diltiazem. Physical examination showed slate-gray to brown reticulated hyperpigmentation in the photo-exposed areas of the face and neck. Histological examination revealed interfac... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5110548 Wed, 10 Aug 2011 18:30:03 +0100 5110548 http://www.medworm.com/index.php?rid=5067652&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21426876%26dopt%3DAbstract Authors: Gámez L, Reig I, González A, Canosa A, Jordá E PMID: 21426876 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5067652 Wed, 27 Jul 2011 12:30:04 +0100 5067652 http://www.medworm.com/index.php?rid=5067651&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21426877%26dopt%3DAbstract Authors: Ortman SA, Huerter C, Reinig E, Albertson D, Sarma DP PMID: 21426877 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=5067651 Wed, 27 Jul 2011 12:30:04 +0100 5067651 http://www.medworm.com/index.php?rid=4969511&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696681%26dopt%3DAbstract This article describes a dermatology curriculum that aims to close the clinical practice gap by providing an efficient and effective way to teach dermatology to medical students and non-dermatology residents in the setting of a busy, outpatient dermatology practice. PMID: 21696681 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969511 Mon, 27 Jun 2011 14:15:08 +0100 4969511 http://www.medworm.com/index.php?rid=4969507&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696682%26dopt%3DAbstract We report a case of cat-associated sporotrichosis in an adult female in California. A retrospectively diagnosed cutaneous sporotrichosis infection in the patient's cat and the unusual site of the primary lesion in the patient contributed to delayed diagnosis and treatment. Here, we also review the English literature regarding the epidemiology of Sporothrix schenkii as a cat-associated zoonosis. PMID: 21696682 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969507 Mon, 27 Jun 2011 14:15:08 +0100 4969507 http://www.medworm.com/index.php?rid=4969504&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696683%26dopt%3DAbstract We report the case of a 9-year-old girl with a lesion on the posterior aspect of the neck, which was clinically compatible with granuloma annulare. An incisional biopsy was performed and the result of the biopsy was consistent with a fibrohistiocytic proliferation. After the total excision of the lesion, the definitive diagnosis of dermatomyofibroma was determined. Dermatomyofibroma is a benign and rare proliferation of myofibroblasts of the skin. Dermatomyofibroma is a solitary and slowly growing tumor. It is more common in adolescents and young adults, with a female preponderance. Dermatomyofibroma presents clinically as a papule or nodule. It may be slightly hyperpigmented. It is usually located on the upper trunk, axilla, upper arm, or neck. The treatment of choice is complete excision... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969504 Mon, 27 Jun 2011 14:15:08 +0100 4969504 http://www.medworm.com/index.php?rid=4969501&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696684%26dopt%3DAbstract Authors: Ratnarathorn M, Craig E Superior vena cava syndrome, which occurs in approximately 15,000 persons in the United States annually, consists of a collection of symptoms and signs resulting from the obstruction of the superior vena cava (SVC). An early and prominent symptom of this condition is a constellation of superficial, dilated, vertically oriented and tortuous cutaneous venules or veins above the ribcage margins, often presenting as a blanchable violaceous eruption. Herein, we report a case of superior vena cava syndrome diagnosed in our dermatology clinic. PMID: 21696684 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969501 Mon, 27 Jun 2011 14:15:08 +0100 4969501 http://www.medworm.com/index.php?rid=4969499&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696685%26dopt%3DAbstract Authors: Moleiro S, Santos V, Calha M, Pessoa G A three-year-old boy presented with 2 months of worsening skin lesions characterized by multiple clear vesicles and bullae. The histopathological and immunohistochemical examinations revealed changes consistent with linear IgA bullous dermatosis of childhood. Treatment with dapsone and prednisolone resulted in gradual clinical improvement. However, within a week of therapy he presented with diabetic ketoacidosis, the onset of type I diabetes mellitus. Since then, keeping this child asymptomatic has been a challenge. This case emphasizes the importance of close monitoring of patients taking systemic corticosteroids; the coexistence of other immune mediated conditions may influence the success of treatment. PMID: 21696685 [PubMed - as s... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969499 Mon, 27 Jun 2011 14:15:08 +0100 4969499 http://www.medworm.com/index.php?rid=4969494&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696686%26dopt%3DAbstract Authors: Stevens T, Sarma DP An excisional biopsy of an asymptomatic cystic lesion that had been present for several years on the right heel of a 48-year-old woman revealed a subcutaneous cyst lined by ciliated columnar epithelium. On immunostaining, the epithelial cells were positive for Pan-cytokeratin (CK AE 1/3), estrogen receptor (ER) and progesterone receptor (PR), but negative for carcinoembryonic antigen (CEA), suggesting Mullerian type of epithelium. Cutaneous ciliated cyst of Mullerian type occurs almost exclusively on the lower extremity of premenopausal women. The lesion is benign and excision is curative. PMID: 21696686 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969494 Mon, 27 Jun 2011 14:15:08 +0100 4969494 http://www.medworm.com/index.php?rid=4969490&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696687%26dopt%3DAbstract We describe a 55-year-old man with a partially eroded lesion on the trunk that developed over one year. Histopathological examination revealed syringocystadenoma papilliferum. A wide excision was performed to remove the tumor. The patient has been well without relapse or metastasis for 8 months. PMID: 21696687 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969490 Mon, 27 Jun 2011 14:15:08 +0100 4969490 http://www.medworm.com/index.php?rid=4969485&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696688%26dopt%3DAbstract We describe a case of a 63-year-old gentleman with an amelanotic SUM that developed after local trauma and presented as a persistent non-healing ulcer which was initially mistaken for a chronic infection. Because amelanotic SUM can mimic other lesions, the physician should have a high index of suspicion for SUM when managing atypical nail lesions to ensure prompt recognition and treatment. The prior trauma to the nail also suggests that posttraumatic inflammation may play a role in SUM development. PMID: 21696688 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969485 Mon, 27 Jun 2011 14:15:08 +0100 4969485 http://www.medworm.com/index.php?rid=4969480&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696689%26dopt%3DAbstract We present a case of multiple warts within a plaque of acanthosis nigricans probably related to autoinoculation. PMID: 21696689 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969480 Mon, 27 Jun 2011 14:15:08 +0100 4969480 http://www.medworm.com/index.php?rid=4969457&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696690%26dopt%3DAbstract We report a case of pemphigus herpetiformis in a 6-year-old girl treated successfully with dapsone. PMID: 21696690 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969457 Mon, 27 Jun 2011 14:15:08 +0100 4969457 http://www.medworm.com/index.php?rid=4969447&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696691%26dopt%3DAbstract We report a case of guttate psoriasis in a patient treated with abatacept for rheumatoid arthritis. This patient had the same reaction with etanercept in the past. PMID: 21696691 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969447 Mon, 27 Jun 2011 14:15:08 +0100 4969447 http://www.medworm.com/index.php?rid=4969433&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696692%26dopt%3DAbstract We report the case of a patient with Kaposi sarcoma in an unusual localization, the penis, which completely resolved with highly active antiretroviral therapy alone. PMID: 21696692 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969433 Mon, 27 Jun 2011 14:15:08 +0100 4969433 http://www.medworm.com/index.php?rid=4969428&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21696693%26dopt%3DAbstract We describe a 93-year-old Japanese woman who developed a painful yellowish plaque with reddish border on her left lower leg. Histological evaluation demonstrated hyaline necrobiosis and granulomatous lesions composed of histiocytes (some with foamy cytoplasm), multinucleated giant cells, and numerous cholesterol crystals. Serum electrophoresis displayed the presence of an M-peak with IgG λ paraproteinemia. There was progressive ulcer formation in the location of the biopsy on the left leg. Multiple tender red dermal and subcutaneous skin nodules developed on her extremities. Oral administration of prednisolone 20 mg daily (0.5 mg/kg) was started. After 4 weeks, she obtained resolution of the skin lesions. PMID: 21696693 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4969428 Mon, 27 Jun 2011 14:15:08 +0100 4969428 http://www.medworm.com/index.php?rid=4922605&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635823%26dopt%3DAbstract We describe a case of MMDH and discuss it in relation to other disseminated digitate keratoses. PMID: 21635823 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922605 Mon, 13 Jun 2011 05:45:04 +0100 4922605 http://www.medworm.com/index.php?rid=4922604&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635824%26dopt%3DAbstract We report on a 43-year-old Caucasian female who presented with bright red macules in a unilateral distribution in the left C5-8 and L3-5 dermatomes. Histopathologic examination showed superficial papillary dermal telangiectasia with minimal chronic inflammation. Immunohistochemical stains for estrogen and progesterone receptors (ER/PR) were negative. A diagnosis of unilateral nevoid telangiectasia syndrome (UNTS) was given. UNTS is an uncommon disorder first described by Alfred Blaschko in 1899. It is comprised of telangiectasias occurring in a predominantly unilateral dermatomal distribution and often affecting the trigeminal, cervical, and upper thoracic dermatomes. It can be either congenital or acquired and has a 2:1 female:male ratio. UNTS has been reported in relation to hyperestroge... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922604 Mon, 13 Jun 2011 05:45:04 +0100 4922604 http://www.medworm.com/index.php?rid=4922603&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635825%26dopt%3DAbstract We report a 17-year-old male with generalized linear porokeratosis, a very rare variant of porokeratosis, with extensive involvement of the trunk and extremities along with nail and genital involvement. The patient was treated with oral acitretin with excellent clinical response. PMID: 21635825 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922603 Mon, 13 Jun 2011 05:45:04 +0100 4922603 http://www.medworm.com/index.php?rid=4922602&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635826%26dopt%3DAbstract We present a case of palatal melanosis related to imatinib therapy for chronic myelogenous leukemia. This case is reported to add to the sparse literature concerning mucosal reactions related to this medication. PMID: 21635826 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922602 Mon, 13 Jun 2011 05:45:04 +0100 4922602 http://www.medworm.com/index.php?rid=4922601&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635827%26dopt%3DAbstract We present a novel variation of an immunocompromised patient who developed fusariosis in a previously irradiated site. Irradiation led to atrophy, contraction, fibrosis, barrier disruption, and an altered dermal environment in which the infection developed. Significantly, this is the first case report of fusariosis in a previously irradiated site of an immunocompromised patient. Treatment included debridement and voriconazole. PMID: 21635827 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922601 Mon, 13 Jun 2011 05:45:04 +0100 4922601 http://www.medworm.com/index.php?rid=4922600&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635828%26dopt%3DAbstract We present a case diagnosed during pregnancy because of the characteristic increase in size of the lesions during this period. PMID: 21635828 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922600 Mon, 13 Jun 2011 05:45:04 +0100 4922600 http://www.medworm.com/index.php?rid=4922599&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635829%26dopt%3DAbstract We report an atypical presentation of GA localized to the palms. PMID: 21635829 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922599 Mon, 13 Jun 2011 05:45:04 +0100 4922599 http://www.medworm.com/index.php?rid=4922598&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635830%26dopt%3DAbstract We report the case of MT with multiple cutaneous gummas and bone and lung involvement that occurred in an apparently immunocompetent patient. PMID: 21635830 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922598 Mon, 13 Jun 2011 05:45:04 +0100 4922598 http://www.medworm.com/index.php?rid=4922597&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635831%26dopt%3DAbstract This report presents the case of a nine-year-old girl with GCTTS arising on her right index finger. PMID: 21635831 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922597 Mon, 13 Jun 2011 05:45:04 +0100 4922597 http://www.medworm.com/index.php?rid=4922596&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635832%26dopt%3DAbstract We report a case of this rare form of psoriasis in an elderly woman with a history of plaque-type psoriasis and and discuss the histopathologic findings. PMID: 21635832 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922596 Mon, 13 Jun 2011 05:45:04 +0100 4922596 http://www.medworm.com/index.php?rid=4922595&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635833%26dopt%3DAbstract Authors: Morrison LK, Lopez IE Yellow plaques and papules on the skin are hallmarks of xanthomas. These are not always associated with abnormalities in lipid profiles or their associated proteins. In cases of diffuse normolipemic plane xanthomas these cutaneous findings are often associated with myelodyscrasias including monoclonal gammopathy of unknown significance and multiple myeloma. Such clinical presentations may indicate that an evaluation for myelodyscrasias is warranted. PMID: 21635833 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922595 Mon, 13 Jun 2011 05:45:04 +0100 4922595 http://www.medworm.com/index.php?rid=4922594&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635834%26dopt%3DAbstract We describe a 12-year-old girl affected by Down syndrome who presented a localized form of EPS, which involved only the extremities. Strangely, it resolved spontaneously after biopsy with no recurrence, without therapy. PMID: 21635834 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922594 Mon, 13 Jun 2011 05:45:04 +0100 4922594 http://www.medworm.com/index.php?rid=4922593&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635835%26dopt%3DAbstract Authors: Antunes J, Silva R, Pacheco D, Travassos R, Filipe P Contact sensitivity to systemically administered drugs occurs mainly among healthcare workers and is frequently caused by antibiotics. A 32-year-old nurse presented with a 1½ year history of hand dermatitis and a 2 month history of palpebral eczema, which were clearly work related. Patch tests with standard and gloves series were negative. Testing of the products commonly handled by the patient were positive for cefradine and cefazolin. Testing of other cephalosporins the patient had not come in contact with were also positive for cefuroxime, ceftriaxone, and cefotaxime. This cross-reactivity may be explained by similar molecular structures. The patient stopped preparing cephalosporin solutions for systemic administration a... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922593 Mon, 13 Jun 2011 05:45:04 +0100 4922593 http://www.medworm.com/index.php?rid=4922592&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21635836%26dopt%3DAbstract We report a new case of sorafenib-induced severe hand-foot skin reaction, which hindered the patient's normal life. The reaction was successfully treated with topical costicosteroids and discontinuation of sorafenib. However, the patient died one month later. PMID: 21635836 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4922592 Mon, 13 Jun 2011 05:45:04 +0100 4922592 http://www.medworm.com/index.php?rid=4876876&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21272504%26dopt%3DAbstract We present the case of a 10-year-old child with borderline Hansen disease, considered unusual in children. She was treated with multibacillary therapy (MB-WHO) with the combination of Rifampicin 600 mg, clofazimine 300 mg, and dapsone 100 mg once a month (the three drugs together on the same day once a month for 18 months); the remaining 28 days of the month, the child received clofazimine 50 mg/day and dapsone 100 mg/day (the two drugs together on the same day 28 days of the month for 18 months). This therapy produced complete remission of the lesions without reactional states. PMID: 21272504 [PubMed - indexed for MEDLINE] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876876 Mon, 30 May 2011 01:30:04 +0100 4876876 http://www.medworm.com/index.php?rid=4876875&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549076%26dopt%3DAbstract Authors: Morais P, Mota A, Eloy C, Lopes JM, Torres F, Palmeiro A, Tavares P, Azevedo F A 13-year-old boy, born prematurely and hypotonic, from non-consanguineous healthy parents, was referred to our department because of easy bruising. A slightly extensible, thin and translucent skin, associated with dysmorphic facies, acrogeria, multiple ecchymoses, hypermobility of the small joints, dorsal kyphosis, genu valgum, flat feet, elongated upper limbs, and low muscle tone were all evident. A history of learning disability and bilateral inguinal hernia was present. Blood and imaging studies were unremarkable. A skin biopsy disclosed an unremarkable dermis; electron microscopy showed abnormalities in the diameter, contour, and shape of collagen fibrils/fibers. Genetic analysis revealed heter... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876875 Mon, 30 May 2011 01:30:04 +0100 4876875 http://www.medworm.com/index.php?rid=4876874&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549077%26dopt%3DAbstract We report a case of cellular neurothekeoma with unusual clinicopathological features in which neuroendocrine markers, determined by immunohistochemistry were observed. Histologically, the tumor showed a micronodular architecture with hypercellular lobules composed of slightly spindled to epithelioid cells, with nuclear atypia or pleomorphism and extension into fat, skeletal muscle. Neoplastic cells were immunoreactive for NKI/C3, CD68, CD10, and smooth-muscle actin, whereas S100 and HMB-45 staining was negative. An intriguing feature was the strong expression by tumor cells of different neuroendocrine markers. Clinical follow up showed no local recurrences after five months despite the presence of positive margins. The presence of atypical histopathological features may cause diagnostic pr... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876874 Mon, 30 May 2011 01:30:04 +0100 4876874 http://www.medworm.com/index.php?rid=4876873&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549078%26dopt%3DAbstract Authors: Atzori L, Pinna AL, Pau M, Aste N Long term D-penicillamine (DPA) therapy to treat Wilson disease can induce elastosis perforans serpiginosa (EPS), a very rare degenerative skin disease characterized by a transepidermal elimination of elastic fiber aggregates. The iatrogenous disease depends on DPA capacity to chelate copper and cause its depletion. Lysyl-oxidase is a copper dependent enzyme crucial to the dermal elastic fiber cross-linking, which is strongly affected by DPA copper depletion. Direct binding of the drug to collagen precursors also affects elastic fiber assemblage and maturation. The abnormal elastin accumulates into the middle dermis and produces a characteristic bramble brush or "lumpy-bumpy" appearance. In this way it acts as a foreign body and is progressive... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876873 Mon, 30 May 2011 01:30:04 +0100 4876873 http://www.medworm.com/index.php?rid=4876872&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549079%26dopt%3DAbstract We report the case of a 17-year-old boy with Neurofibromatosis 1 with Noonan-like features, who complained of the progressive appearance of blue-gray lesions on his back. PMID: 21549079 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876872 Mon, 30 May 2011 01:30:04 +0100 4876872 http://www.medworm.com/index.php?rid=4876871&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549080%26dopt%3DAbstract Authors: Corry A, Feighery C, Alderdice D, Stewart F, Walsh M, Dolan OM This case presents a 39-year-old gentleman with a single angiokeratoma on the abdomen. Because of a family history of early onset cardiac disease, testing for Fabry disease was performed and a mis-sense mutation (A143T) in the Fabry gene confirmed the diagnosis. The unusual aspect of this case is that the patient otherwise had normal health. His only detectable abnormality was a high serum creatinine at 116 mmol/L. Two further affected males and four carrier females were detected on family screening. We tested a further five patients with a single angiokeratoma for Fabry disease. In the five tested though, no suggestive personal or family history was given for any of the patients and no further cases were detected.... Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876871 Mon, 30 May 2011 01:30:04 +0100 4876871 http://www.medworm.com/index.php?rid=4876870&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549081%26dopt%3DAbstract We report a case of a 78-year-old male with an extensive GF of the scalp successfully treated with pulsed dye laser (PDL). PMID: 21549081 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876870 Mon, 30 May 2011 01:30:04 +0100 4876870 http://www.medworm.com/index.php?rid=4876869&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549082%26dopt%3DAbstract CONCLUSION: The peculiarities in our case include the presence of this disorder in both female siblings along with alopecia in the younger sibling. Hyperlipidemia, noted in one of our cases, is also not a common association. Diagnosing DCS is fairly simple and a high index of suspicion may lead to higher rates of detection of this rare disorder. PMID: 21549082 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876869 Mon, 30 May 2011 01:30:04 +0100 4876869 http://www.medworm.com/index.php?rid=4876868&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549083%26dopt%3DAbstract Authors: Aneiros-Fernandez J, Arias-Santiago S, Husein-Elahmed H, Fernandez-Pugnaire MA, O'Valle F PMID: 21549083 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876868 Mon, 30 May 2011 01:30:04 +0100 4876868 http://www.medworm.com/index.php?rid=4876867&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549084%26dopt%3DAbstract Authors: Frandsen J, Enslow M, Bowen AR A 53-year-old woman presented with an enlarging, tender, ulcerated nodule on her dorsal hand after being scratched by a stray kitten. Histology was consistent with orf parapoxvirus infection. The lesion resolved without scarring after several weeks of treatment with imiquimod 5 percent cream. Orf is a zoonosis transmitted to humans from sheep and goats by direct contact or by fomites. Transmission by cat scratch has not been previously described in the literature. PMID: 21549084 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876867 Mon, 30 May 2011 01:30:04 +0100 4876867 http://www.medworm.com/index.php?rid=4876866&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549085%26dopt%3DAbstract We report a 65-year-old woman who presented with a melanoma arising in a nevus spilus that had been present since birth. PMID: 21549085 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876866 Mon, 30 May 2011 01:30:04 +0100 4876866 http://www.medworm.com/index.php?rid=4876865&cid=s_31723_12_f&fid=31723&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21549086%26dopt%3DAbstract We present a case of MLC in which the cutaneous affectation was the first sign of the systemic leukemia. In this setting, the myeloperoxidase stain was the clue to rule out the possibility of HSS. We discuss the role and the utility of the myeloperoxidase stain in the differentiation of these two entities. PMID: 21549086 [PubMed - in process] (Source: Dermatol Online J) Dermatol Online J journals http://www.medworm.com/rss/comments.php?id=4876865 Mon, 30 May 2011 01:30:04 +0100 4876865