MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Dermatologic Clinics' source. Tue, 02 Mar 2010 14:14:45 +0100 http://www.medworm.com/index.php?rid=3041134&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350900117X%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041134 Tue, 01 Dec 2009 14:33:07 +0100 3041134 http://www.medworm.com/index.php?rid=3041133&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350900093X%2Fabstract%3Frss%3Dyes Quality of life (QOL) evaluation in epidermolysis bullosa (EB) has important applications in clinical management, patient advocacy, clinical research, and the development of new treatments. Several new quantitative and qualitative QOL measurement tools were developed recently, providing insight into the impact EB has on individuals and their family members. Selection of the most appropriate QOL tool for patients who have EB depends on not only the type of information required but also the general or specific cohort being examined. EB-specific quantitative tools possess the highest level of content validity and statistical accuracy. However, generic dermatologic tools may also be appropriate in some circumstances. Overall, QOL evaluation in EB is still a developing area of research that may... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041133 Tue, 01 Dec 2009 14:33:07 +0100 3041133 http://www.medworm.com/index.php?rid=3041132&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000989%2Fabstract%3Frss%3Dyes Epidermolysis bullosa (EB) nevi are large, eruptive, asymmetrical, often irregularly pigmented melanocytic lesions. Such nevi may give rise to small satellite nevi surrounding the primary nevus, and thus frequently manifest clinical features suggestive of melanoma. They usually arise in sites of previous bullae or erosions. At least twice a year all persisting wounds and EB nevi should be evaluated with a low threshold for histopathologic examination if warranted. Our practice is to punch biopsy EB nevi showing dermoscopic features of concern as well as dermoscopically featureless lesions. Given the skin fragility and potentially impaired wound healing in EB patients, we avoid prophylactic total excision of large EB nevi, but rather use the dermoscope to select appropriate sites for punch ... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041132 Tue, 01 Dec 2009 14:33:07 +0100 3041132 http://www.medworm.com/index.php?rid=3041131&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000977%2Fabstract%3Frss%3Dyes Patients with recessive dystrophic epidermolysis bullosa develop numerous life-threatening skin cancers. The reasons for this remain unclear. Parallels exist with other scarring skin conditions, such as Marjolin ulcer. We summarize observational and experimental data and discuss proposed theories for the development of such aggressive skin cancers. A context-driven situation seems to be emerging, but more focused research is required to elucidate the pathogenesis of epidermolysis bullosa–associated squamous cell carcinoma. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041131 Tue, 01 Dec 2009 14:33:07 +0100 3041131 http://www.medworm.com/index.php?rid=3041130&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000928%2Fabstract%3Frss%3Dyes This article reviews the hair abnormalities reported in the different subtypes of EB. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041130 Tue, 01 Dec 2009 14:33:07 +0100 3041130 http://www.medworm.com/index.php?rid=3041129&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000965%2Fabstract%3Frss%3Dyes The craniofacial and oral manifestations of the different epidermolysis bullosa (EB) types vary markedly in character and severity depending largely on the EB type. The tissues affected and the phenotypes displayed are closely related to the specific abnormal or absent proteins resulting from the causative genetic mutations for these disorders. In this article, the major oral manifestations are reviewed for different EB subtypes and are related to the causative genetic mutations and gene expression. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041129 Tue, 01 Dec 2009 14:33:07 +0100 3041129 http://www.medworm.com/index.php?rid=3041128&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000916%2Fabstract%3Frss%3Dyes This article reviews the nail abnormalities observed in EB. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041128 Tue, 01 Dec 2009 14:33:07 +0100 3041128 http://www.medworm.com/index.php?rid=3041127&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000953%2Fabstract%3Frss%3Dyes This article describes these signs and symptoms. It also offers options for treatment. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041127 Tue, 01 Dec 2009 14:33:07 +0100 3041127 http://www.medworm.com/index.php?rid=3041126&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000904%2Fabstract%3Frss%3Dyes For more than 2 decades, animal models have been used to clarify the pathogenic mechanisms of human diseases and develop new therapeutics for these diseases. Several therapies for human diseases have become available through trials using animal models. Epidermolysis bullosa (EB) is one of the most severe inherited skin disorders, whose effective treatments have not been fully available. EB is characterized by abnormalities of the proteins that consist of the dermoepidermal junction. EB has been classified into three major subtypes according to the level of skin cleavage: EB simplex, junctional EB, and dystrophic EB. To date, 13 genes have been shown to cause EB phenotype. After the discovery of the causative genes responsible for each EB subtype, many researchers have tried to develop EB a... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041126 Tue, 01 Dec 2009 14:33:07 +0100 3041126 http://www.medworm.com/index.php?rid=3041125&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000898%2Fabstract%3Frss%3Dyes This article provides a clinicopathologic overview of this unique desmosomal genodermatosis, set in the context of other DSP gene mutations, both dominant and recessive, that can cause a spectrum of skin, hair, and heart abnormalities. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041125 Tue, 01 Dec 2009 14:33:07 +0100 3041125 http://www.medworm.com/index.php?rid=3041124&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000886%2Fabstract%3Frss%3Dyes This article reviews the clinical, structural, and molecular pathology of this genetic disorder of desmosomes. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041124 Tue, 01 Dec 2009 14:33:06 +0100 3041124 http://www.medworm.com/index.php?rid=3041123&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000874%2Fabstract%3Frss%3Dyes This article reviews clinicopathologic and molecular features of Kindler syndrome and discusses patient management. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041123 Tue, 01 Dec 2009 14:33:06 +0100 3041123 http://www.medworm.com/index.php?rid=3041122&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000862%2Fabstract%3Frss%3Dyes Kindler syndrome is caused by genetic defects in the focal contact–associated protein, fermitin family homologue 1 (FFH1), encoded by the gene FERMT1 (known as KIND1). Defects in FFH1 lead to abnormal integrin activation and loss of keratinocyte epidermal adhesion to the underlying basal lamina, disruption in normal cell cytoskeleton within keratinocytes, and altered signaling pathways, leading to increased extracellular matrix production. Null mutations in FERMT1 result in skin blistering from birth and early childhood progressive poikiloderma, mucosal fragility, and increased risk of cancer. The complete range of FFH1 functions in skin and other epithelia has yet to be determined. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041122 Tue, 01 Dec 2009 14:33:06 +0100 3041122 http://www.medworm.com/index.php?rid=3041121&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000941%2Fabstract%3Frss%3Dyes This article describes the pathogenesis and clinical features of DEB. It also describes therapeutic options and the future of molecular therapies. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041121 Tue, 01 Dec 2009 14:33:06 +0100 3041121 http://www.medworm.com/index.php?rid=3041120&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000850%2Fabstract%3Frss%3Dyes Type VII collagen is a major component of the anchoring fibrils of the dermal-epidermal adhesion on the dermal side at the lamina densa/papillary dermis interface. Dystrophic epidermolysis bullosa (DEB) emerged as a candidate for type VII collagen mutations becausing anchoring fibrils were shown to be morphologically altered, reduced in number, or completely absent in patients with different forms of DEB. Circulating autoantibodies recognize type VII collagen epitopes in epidermolysis bullosa acquisita. The suggestion that type VII collagen is required for human epidermal tumorigenesis relates to the increasing numbers of life-threatening complications associated with developing squamous cell carcinomas because of the extended life span of affected individuals with recessive DEB. (Source: ... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041120 Tue, 01 Dec 2009 14:33:06 +0100 3041120 http://www.medworm.com/index.php?rid=3041119&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000849%2Fabstract%3Frss%3Dyes Laryngo-onycho-cutaneous (LOC) syndrome was reclassified as a subtype of junctional epidermolysis bullosa (JEB) based on clinical features similar to JEB and its association, in the majority of patients from the Punjab, with a unique mutation affecting the N terminus of the α3 chain of LM332. Although LOC syndrome is now a subtype of JEB(JEB-LOC) JEB-LOC has a distinct clinicopathologic appearance and molecular fingerprint. The intricacies of the JEB-LOC subtype are discussed in this article with regard to disease presentation, pathogenesis, management, and prognosis. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041119 Tue, 01 Dec 2009 14:33:06 +0100 3041119 http://www.medworm.com/index.php?rid=3041118&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000837%2Fabstract%3Frss%3Dyes This article provides an overview of the gene, transcripts, and protein structures of laminin α3. Also discussed are the proposed functions for the α3 subunit–containing laminins. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041118 Tue, 01 Dec 2009 14:33:06 +0100 3041118 http://www.medworm.com/index.php?rid=3041117&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000825%2Fabstract%3Frss%3Dyes Non-Herlitz junctional epidermolysis bullosa (nH JEB) is characterized by generalized blisters that predominate in sites exposed to friction, trauma, or heat. Whereas infants and children with nH JEB often appear to resemble patients with other forms of EB, adults with this disorder typically display atrophic scars, hypopigmentation, or hyperpigmentation at sites of healed blisters as well as incomplete alopecia, dystrophic nails, mucous membrane involvement, and dental abnormalities. Mild (or severe) disease early in life may be characterized by the opposite phenotype in adults with nH JEB. Although nH JEB is generally less severe than Herlitz disease, fatalities (especially in neonates) are not uncommon among patients with the former diagnosis. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041117 Tue, 01 Dec 2009 14:33:06 +0100 3041117 http://www.medworm.com/index.php?rid=3041116&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000813%2Fabstract%3Frss%3Dyes This article examines the genetic and pathological features of collagen XVII. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041116 Tue, 01 Dec 2009 14:33:06 +0100 3041116 http://www.medworm.com/index.php?rid=3041115&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000801%2Fabstract%3Frss%3Dyes This article outlines the epidemiology, presentation, and diagnosis of JEB-H. Morbidity and mortality are high, necessitating optimized protocols for early (including prenatal) diagnosis and palliative care. Gene therapy remains the most promising perspective. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041115 Tue, 01 Dec 2009 14:33:05 +0100 3041115 http://www.medworm.com/index.php?rid=3041114&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000795%2Fabstract%3Frss%3Dyes This article describes the clinical and pathologic features and molecular genetics of EB-PA, the mutations in the α6β4 integrin and plectin genes that cause EB-PA, and the clinical implications of molecular genetics on EB-PA. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041114 Tue, 01 Dec 2009 14:33:05 +0100 3041114 http://www.medworm.com/index.php?rid=3041113&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000783%2Fabstract%3Frss%3Dyes Plectin is an important organizer of the keratin filament cytoskeleton in basal keratinocytes. It is essential for anchoring these filaments to the extracellular matrix via hemidesmosomal integrins. Loss of plectin or incorrect function of the protein due to mutations in its gene can lead to various forms of the skin blistering disease, epidermolysis bullosa simplex. Severity and subtype of the disease is dependent on the specific mutation and can be associated with (late-onset) muscular dystrophy or pyloric atresia. Mouse models mimicking the human phenotypes allow detailed study of plectin function. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041113 Tue, 01 Dec 2009 14:33:05 +0100 3041113 http://www.medworm.com/index.php?rid=3041112&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000771%2Fabstract%3Frss%3Dyes The prevalence of epidermolysis bullosa simplex (EBS) is estimated to be approximately 6 to 30 per 1 million live births. The disease is usually caused by missense mutations in KRT5 and KRT14, encoding keratins mostly expressed in the epidermal basal layer. Major advances in understanding of the molecular basis of EBS and other keratin disorders have led to the development of DNA-based prenatal testing. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041112 Tue, 01 Dec 2009 14:33:05 +0100 3041112 http://www.medworm.com/index.php?rid=3041111&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350900076X%2Fabstract%3Frss%3Dyes This article reviews how different types of mutation may result in defective gene expression. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041111 Tue, 01 Dec 2009 14:33:05 +0100 3041111 http://www.medworm.com/index.php?rid=3041110&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000758%2Fabstract%3Frss%3Dyes This article identifies key molecular players of the dermal-epidermal membrane zone, and highlights recent research studies that have identified structural and functional roles of these components in the context of various blistering, neoplastic, and developmental syndromes. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041110 Tue, 01 Dec 2009 14:33:05 +0100 3041110 http://www.medworm.com/index.php?rid=3041109&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509001090%2Fabstract%3Frss%3Dyes When invited by Bruce Thiers to edit a special issue of Dermatologic Clinics on epidermolysis bullosa (EB), I was delighted and honored to accept. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041109 Tue, 01 Dec 2009 14:33:05 +0100 3041109 http://www.medworm.com/index.php?rid=3041108&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509001168%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041108 Tue, 01 Dec 2009 14:33:05 +0100 3041108 http://www.medworm.com/index.php?rid=3041107&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509001156%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=3041107 Tue, 01 Dec 2009 14:33:05 +0100 3041107 http://www.medworm.com/index.php?rid=2913772&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000709%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913772 Wed, 30 Sep 2009 23:00:00 +0100 2913772 http://www.medworm.com/index.php?rid=2913771&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000540%2Fabstract%3Frss%3Dyes The history of classifying skin types is rather new and there has been considerable progress made with continuing awareness. The Fitzpatrick Skin Phototype Classification remains the gold standard. It is simple and user friendly, however this system fails to accurately predict skin reactions. The Roberts Skin Type Classification System is a tool to predict the skin response to injury and insult from cosmetic procedures and identify the propensity of sequelae from inflammatory skin disorders. It can be a predictor of an impending complication, such as hyperpigmentation and scarring, which can then be avoided. In addition, it includes the skin phototype and photoage. In evaluating patients' skin and developing a cosmetic plan, the four indices outlined in this article, hyper/hypopigmentation... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913771 Wed, 30 Sep 2009 23:00:00 +0100 2913771 http://www.medworm.com/index.php?rid=2913770&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000527%2Fabstract%3Frss%3Dyes Recent advances in technology have drastically improved aesthetic treatment for skin. Of particular interest is the emergence of laser- and lightbased technologies, which have offered great promise among skin-rejuvenation therapies. New laser resurfacing techniques for skin rejuvenation offer significant advantages over conventional ablative lasers, such as the CO2 and erbiumYAG laser systems. Nonablative and fractional lasers, although not as efficacious as ablative therapies, are associated with significantly diminished complication rates and shortened recovery times. Novel devices combining ablative and fractional technologies have also surfaced, demonstrating noteworthy results. In this review, the authors will discuss the implications of current developments in research and technology... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913770 Wed, 30 Sep 2009 23:00:00 +0100 2913770 http://www.medworm.com/index.php?rid=2913769&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000618%2Fabstract%3Frss%3Dyes This article reviews potential complications of these procedures and best practices for clinical management to improve outcomes. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913769 Wed, 30 Sep 2009 23:00:00 +0100 2913769 http://www.medworm.com/index.php?rid=2913768&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000503%2Fabstract%3Frss%3Dyes This article will discuss the concept of negligence and the potential for medical malpractice, including the associated problems that may arise when these procedures are performed by physician extenders. The impact of the physician and physician extender relationship, and the legal issues that arise, are also discussed. The article concludes with the legal and ethical issues associated with the promotion of cosmeceutical agents in the field of cosmetic dermatology. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913768 Wed, 30 Sep 2009 23:00:00 +0100 2913768 http://www.medworm.com/index.php?rid=2913767&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000564%2Fabstract%3Frss%3Dyes Results with current skin-tightening technologies are mild to moderate and are not intended to replace surgical procedures. Many patients will choose more subtle tightening to avoid the risks and downtime associated with surgery. Newer treatment protocols have improved treatment predictability and the extent of efficacy, and novel technologies with the potential for even greater results are currently in development. Overall patients' satisfaction can be increased by combining skin tightening with complementary, noninvasive skin treatments, such as botulinum toxin and soft-tissue fillers. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913767 Wed, 30 Sep 2009 23:00:00 +0100 2913767 http://www.medworm.com/index.php?rid=2913766&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000576%2Fabstract%3Frss%3Dyes The field of nonsurgical laser resurfacing for aesthetic enhancement continues to improve with new research and technological advances. Since its beginnings in the 1980s, the laser-resurfacing industry has produced a multitude of devices employing ablative, nonablative, and fractional ablative technologies. The three approaches largely differ in their method of thermal damage, weighing degrees of efficacy, downtime, and side effect profiles against each other. Nonablative technologies generate some interest, although only for those patient populations seeking mild improvements. Fractional technologies, however, have gained dramatic ground on fully ablative resurfacing. Fractional laser resurfacing, while exhibiting results that fall just short of the ideal outcomes of fully ablative treatm... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913766 Wed, 30 Sep 2009 23:00:00 +0100 2913766 http://www.medworm.com/index.php?rid=2913765&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350900059X%2Fabstract%3Frss%3Dyes This article discussed the science, clinical indications, patient selection and preparation, posttreatment care, and complications of NFR. It concludes that the most impressive clinical results are seen with acne scars, surgical and traumatic scars, and mild to moderate facial and nonfacial dyschromia or photoaging. Modest results can be seen with therapy-resistant melasma and certain types of rhytides. Future approaches include synergistic treatments with radiofrequency devices and the development of novel wavelengths to enhance the efficacy of NFR while preserving safety. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913765 Wed, 30 Sep 2009 23:00:00 +0100 2913765 http://www.medworm.com/index.php?rid=2913764&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000588%2Fabstract%3Frss%3Dyes This article reviews the causes of acne, the treatment options, and grading scales. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913764 Wed, 30 Sep 2009 23:00:00 +0100 2913764 http://www.medworm.com/index.php?rid=2913763&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000552%2Fabstract%3Frss%3Dyes This article explores the technology, clinical applications, side effects, and future directions of photorejuvenation with vascular lasers, pigmented lasers, and intense pulsed light sources. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913763 Wed, 30 Sep 2009 23:00:00 +0100 2913763 http://www.medworm.com/index.php?rid=2913762&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000515%2Fabstract%3Frss%3Dyes Today, an impressive array of injectable dermal fillers for facial soft-tissue augmentation is available in the United States. These agents, most of which were introduced in the last half decade, represent a variety of semipermanent and permanent fillers across several categories. Physicians can choose between semipermanent fillers, such as hyaluronic acid derivatives (HA), calcium hydroxylapatite (CaHA), and poly-L-lactic acid (PLA), and longer-lasting, so-called “permanent fillers,” such as polymethyl methacrylate microspheres (PMMA), highly purified forms of liquid silicone, and hydrogel polymers. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913762 Wed, 30 Sep 2009 23:00:00 +0100 2913762 http://www.medworm.com/index.php?rid=2913761&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000606%2Fabstract%3Frss%3Dyes Until recently, the use of dermal fillers was limited in the United States by the small number of products approved by the Food and Drug Administration. The products now approved for use in the United States have opened up the range of possibilities for combinations of products that are synergistic in their effects. Combinations of products may be discussed in temporal or anatomic relationships. Temporal combinations refer to the use of different fillers at different times, whereas anatomic combinations refer to the use of different fillers in different parts of the face. Before discussing how the various fillers may be used in combination, it is worthwhile to consider their use in isolation. Soft-tissue augmentation products under consideration in the present article include the hyaluroni... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913761 Wed, 30 Sep 2009 23:00:00 +0100 2913761 http://www.medworm.com/index.php?rid=2913760&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000497%2Fabstract%3Frss%3Dyes Since its initial approval by the US Food and Drug Administration (FDA) 20 years ago for the treatment of strabismus, hemifacial spasm, and blepharospasm in adults, botulinum toxin (BTX) has become one of the most frequently requested products in cosmetic rejuvenation around the world. After years of clinical success and consistent safety in the upper face, the use of BTX has expanded and evolved to include increasingly complicated indications. In the hands of adept injectors, the focus has shifted from the treatment of individual dynamic rhytides to shaping, contouring, and sculpting, alone or in combination with other cosmetic procedures, to enhance the aesthetic appearance of the face. Although recent reports have questioned the safety of BTX, 25 years of therapeutic and over 20 years o... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913760 Wed, 30 Sep 2009 23:00:00 +0100 2913760 http://www.medworm.com/index.php?rid=2913759&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000539%2Fabstract%3Frss%3Dyes This article reviews how to incorporate various cosmeceuticals into the treatment regime of patients, depending on the diagnosis and therapies chosen. The practical application of when, why, and on whom to use different products will enable dermatologists to improve the methodology of product selection and, ultimately, improve patient's clinical results. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913759 Wed, 30 Sep 2009 23:00:00 +0100 2913759 http://www.medworm.com/index.php?rid=2913758&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350900062X%2Fabstract%3Frss%3Dyes Cosmetic dermatology is truly undergoing a renaissance. Just 10 years ago, dermatologists had limited tools in their armamentarium to address the myriad appearance-related issues in the field. The big bang of cosmetic dermatology occurred with the cosmetic use of botulinum toxins. This addressed one of the four Rs in global rejuvenation—relaxation of muscles of facial expression. The use of botulinum toxins has grown from merely addressing glabellar rhytids to the sophisticated use in facial shaping. The rapid development of dermal fillers soon exploded, addressing the second R—refilling of loss of facial and nonfacial volume. For the majority of the twentieth century, dermal fillers were limited to collagens and the concept of filling in lines. The explosion of varieties of classes of... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913758 Wed, 30 Sep 2009 23:00:00 +0100 2913758 http://www.medworm.com/index.php?rid=2913757&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000692%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913757 Wed, 30 Sep 2009 23:00:00 +0100 2913757 http://www.medworm.com/index.php?rid=2913756&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000680%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2913756 Wed, 30 Sep 2009 23:00:00 +0100 2913756 http://www.medworm.com/index.php?rid=2574245&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000382%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574245 Tue, 30 Jun 2009 23:00:00 +0100 2574245 http://www.medworm.com/index.php?rid=2574244&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000217%2Fabstract%3Frss%3Dyes This article reviews governmental regulations-some helpful for patients and workers and some not helpful for dermatologists in their quest to assist patients with contact dermatitis. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574244 Tue, 30 Jun 2009 23:00:00 +0100 2574244 http://www.medworm.com/index.php?rid=2574243&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000175%2Fabstract%3Frss%3Dyes Contact dermatitis is the most common occupational skin disorder, responsible for up to 30% of all cases of occupational disease in industrialized nations. Epidemiologic data suggest that contact dermatitis accounts for 90% to 95% of all cases of occupational skin disease, imposing considerable social and economic implications. Occupational contact dermatitis is broadly classified into allergic and irritant subtypes. Irritant contact dermatitis is widely quoted in the literature to account for 80% of occupational contact dermatitis cases, with allergic cases held responsible for the remaining 20%. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574243 Tue, 30 Jun 2009 23:00:00 +0100 2574243 http://www.medworm.com/index.php?rid=2574242&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000205%2Fabstract%3Frss%3Dyes This article on SCD provides an overview of the disease with descriptions of common allergens and some insight into the possible mechanism of action seen in SCD. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574242 Tue, 30 Jun 2009 23:00:00 +0100 2574242 http://www.medworm.com/index.php?rid=2574241&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350900028X%2Fabstract%3Frss%3Dyes This article presents the case for a standard, broad definition of this condition and reviews the epidemiology, clinical features, etiology, and treatment of acute and recurrent vesicular hand dermatitis with special emphasis on endogenous causes. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574241 Tue, 30 Jun 2009 23:00:00 +0100 2574241 http://www.medworm.com/index.php?rid=2574240&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000242%2Fabstract%3Frss%3Dyes Patch testing can be particularly rewarding when skin-care product allergens are identified. Careful determination of relevance, followed by careful education regarding allergen avoidance, can result in dramatic clinical improvement. Several common clinical scenarios are reviewed with a focus on pragmatic solutions to heighten positive patient outcomes. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574240 Tue, 30 Jun 2009 23:00:00 +0100 2574240 http://www.medworm.com/index.php?rid=2574239&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000266%2Fabstract%3Frss%3Dyes Patient education plays an important role in empowering patients who have allergic contact dermatitis. Having the knowledge about a disease process does not guarantee healthy behaviors. Through careful assessment of educational needs, awareness of stages of change that adults go through, and use of resources available to members of the American Contact Dermatology Society, nurses can provide patient education that completes the patch testing process. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574239 Tue, 30 Jun 2009 23:00:00 +0100 2574239 http://www.medworm.com/index.php?rid=2574238&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000163%2Fabstract%3Frss%3Dyes From as early as 1869, textile dyes and subsequently finishes have been reported to cause various manifestations of contact dermatitis, from mild to severe and debilitating. The European Union, through Directive (2002/61/EC) to restrict the marketing and use of certain dangerous substances and preparations (azo colorants) in textile and leather products, has taken the worldwide lead in restricting some dyes as a result of their carcinogenic nature. Given the recent discovery of the new route to contact dermatitis, it is important to continue to be vigilant for new and unexpected sources of allergens from textile, apparel, and furniture items. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574238 Tue, 30 Jun 2009 23:00:00 +0100 2574238 http://www.medworm.com/index.php?rid=2574237&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000254%2Fabstract%3Frss%3Dyes This article reviews the characteristic clinical patterns of phyto- and phytophotodermatitis and some less common presentations. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574237 Tue, 30 Jun 2009 23:00:00 +0100 2574237 http://www.medworm.com/index.php?rid=2574236&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000187%2Fabstract%3Frss%3Dyes Allergic contact dermatitis to topical medicaments occurs often. Common medicaments associated with allergic contact dermatitis include topically applied antibiotics, antihistamines, nonsteroidal antiinflammatory drugs, anesthetics, and corticosteroids. In cases of suspected allergic contact dermatitis, medicaments that the patient is using should be included when patch testing. Body sites susceptible to allergic contact dermatitis to topical medicaments include scalp, face, anogenital area, and lower extremities. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574236 Tue, 30 Jun 2009 23:00:00 +0100 2574236 http://www.medworm.com/index.php?rid=2574235&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000230%2Fabstract%3Frss%3Dyes The anatomic distribution of dermatitis affecting the hands and feet can provide clues to the likelihood that a contact allergen is provoking the dermatitis. Dermatitis presenting on the hands or feet, but not both, is more likely because of allergic contact dermatitis, whereas dermatitis affecting both the hands and feet is more likely a result of a systemic cause. Exceptions are reviewed in this article. When allergic contact dermatitis affects only the hands and feet, rubber chemicals and chromates are the most common allergens. Pattern recognition can assist with choice of patch test allergens, counseling regarding routes of exposure, and selection of alternative contactants. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574235 Tue, 30 Jun 2009 23:00:00 +0100 2574235 http://www.medworm.com/index.php?rid=2574234&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000291%2Fabstract%3Frss%3Dyes Certain patterns of dermatitis, such as those affecting the face, eyelids, lips, and neck, should raise the suspicion of a cosmetic-related contact allergy. Patch testing with a broad screening series, supplemented by a patient's own personal care products, should be considered when evaluating patients with suspected cosmetic dermatitis. Once the offending allergen is identified, an avoidance regimen should be established to avoid further exposure. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574234 Tue, 30 Jun 2009 23:00:00 +0100 2574234 http://www.medworm.com/index.php?rid=2574233&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000229%2Fabstract%3Frss%3Dyes This article reviews common biocides implicated in hand dermatitis. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574233 Tue, 30 Jun 2009 23:00:00 +0100 2574233 http://www.medworm.com/index.php?rid=2574232&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000278%2Fabstract%3Frss%3Dyes Plastic resin systems have an increasingly diverse array of applications but also induce health hazards, the most common of which are allergic and irritant contact dermatitis. Contact urticaria, pigmentary changes, and photoallergic contact dermatitis may occasionally occur. Other health effects, especially respiratory and neurologic signs and symptoms, have also been reported. These resin systems include epoxies, the most frequent synthetic resin systems to cause contact dermatitis, (meth)acrylics, polyurethanes, phenol-formaldehydes, polyesters, amino resins (melamine-formaldehydes, urea-formaldehydes), polyvinyls, polystyrenes, polyolefins, polyamides and polycarbonates. Contact dermatitis usually occurs as a result of exposure to the monomers and additives in the occupational setting, ... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574232 Tue, 30 Jun 2009 23:00:00 +0100 2574232 http://www.medworm.com/index.php?rid=2574231&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000199%2Fabstract%3Frss%3Dyes The diagnosis of a contact allergy requires several important and essential steps, because the failure to recognize a contact allergy can occur in any of the various stages of the contact allergy investigation. If the results of the skin tests are negative for a patient for whom a diagnosis of allergic contact dermatitis has been proposed, one has to go back to the beginning, that is, with a thoroughgoing anamnesis of the patient (perhaps with a visit to his or her environment). The assumed allergens must be retested (perhaps in another concentration, with another vehicle, or with another testing method), and additional allergens must be tested. The patient can also be asked to keep a journal, in the hope that a correlation can be discerned between exposure to a substance and the occurrenc... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574231 Tue, 30 Jun 2009 23:00:00 +0100 2574231 http://www.medworm.com/index.php?rid=2574230&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000308%2Fabstract%3Frss%3Dyes Diagnosis and treatment of allergic contact dermatitis is one of the most gratifying patient interactions in dermatology. Successful identification of an allergen and subsequent allergen avoidance patient education can lead to cure without side effects of drugs, additional procedures, or need for frequent physician visits. Often patients return to the workforce. Quality of life improves. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574230 Tue, 30 Jun 2009 23:00:00 +0100 2574230 http://www.medworm.com/index.php?rid=2574229&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000370%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574229 Tue, 30 Jun 2009 23:00:00 +0100 2574229 http://www.medworm.com/index.php?rid=2574228&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000369%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2574228 Tue, 30 Jun 2009 23:00:00 +0100 2574228 http://www.medworm.com/index.php?rid=2350279&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000096%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350279 Wed, 01 Apr 2009 04:00:00 +0100 2350279 http://www.medworm.com/index.php?rid=2350278&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001113%2Fabstract%3Frss%3Dyes This article reviews the research on, and examines the epidemiology and prevention of melanoma. Despite the great quantity of research into environmental and genetic causes, and the ease of diagnosis, incidence and mortality have risen in all developed countries during the last half century. Patient and physician education, and public health programs aimed at prevention, have had varied success. The authors conclude that, until we have better data on how to prevent skin cancer of all types, the best solutions are education of high-risk populations about skin self-evaluation in combination with physician examination to practice; and sun protection. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350278 Wed, 01 Apr 2009 04:00:00 +0100 2350278 http://www.medworm.com/index.php?rid=2350277&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001034%2Fabstract%3Frss%3Dyes This article provides instruction on how to effectively review a life sciences manuscript, particularly those in dermatology. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350277 Wed, 01 Apr 2009 04:00:00 +0100 2350277 http://www.medworm.com/index.php?rid=2350276&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350800106X%2Fabstract%3Frss%3Dyes Many Internet resources for dermatologists benefit public health by providing education and information on the diagnosis and treatment of skin conditions. A variety of dermatology resources exist on the Web, but finding quality resources can be time-consuming. The authors provide a collection of high-quality, freely accessible, English-language Web sites that they have categorized as clinical, educational, or evidence-based medicine resources. They hope that this list of sources helps to meet the informational needs of dermatologists and promotes skin disease awareness and education. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350276 Wed, 01 Apr 2009 04:00:00 +0100 2350276 http://www.medworm.com/index.php?rid=2350275&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001022%2Fabstract%3Frss%3Dyes A medical “registry” is a systematic collection of information from cases of a particular disease or other health relevant condition. Hospital-based registries primarily address prognosis, whereas population-based registries provide estimates of disease incidence. Opportunities to establish and investigate dermatology hospital- and population-based registries abound. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350275 Wed, 01 Apr 2009 04:00:00 +0100 2350275 http://www.medworm.com/index.php?rid=2350274&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508000983%2Fabstract%3Frss%3Dyes This article describes recent developments in health care consumer activism including dermatology disease advocacy and efforts to improve dermatologist-patient interactions. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350274 Wed, 01 Apr 2009 04:00:00 +0100 2350274 http://www.medworm.com/index.php?rid=2350273&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001009%2Fabstract%3Frss%3Dyes In this article, the authors summarize the published literature on the reliability and accuracy of teledermatology. The first section reports on the diagnostic reliability of teledermatology compared with face-to-face clinic consultation. In the second section, the authors report on the “intragroup” diagnostic agreement between either clinic dermatologists or teledermatologists. The third section discusses the diagnostic accuracy for those studies that include definitive histopathologic diagnosis. The last section summarizes the literature comparing clinical management decisions by clinic dermatologists to those made by teledermatologists. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350273 Wed, 01 Apr 2009 04:00:00 +0100 2350273 http://www.medworm.com/index.php?rid=2350272&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001010%2Fabstract%3Frss%3Dyes This article summarizes primary prevention strategies as well as management of patients already sensitized to nickel. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350272 Wed, 01 Apr 2009 04:00:00 +0100 2350272 http://www.medworm.com/index.php?rid=2350271&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001071%2Fabstract%3Frss%3Dyes This article analyzes these health risks and benefits and discusses pertinent issues surrounding indoor tanning, the role of sunless tanning products, and prudent sun exposure. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350271 Wed, 01 Apr 2009 04:00:00 +0100 2350271 http://www.medworm.com/index.php?rid=2350270&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001095%2Fabstract%3Frss%3Dyes This article discusses observational studies that assess comorbidities in psoriasis, atopic dermatitis, vitiligo, and nonmelanoma skin cancer, and the likelihood of the observed associations and their clinical consequences. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350270 Wed, 01 Apr 2009 04:00:00 +0100 2350270 http://www.medworm.com/index.php?rid=2350269&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001083%2Fabstract%3Frss%3Dyes Social media websites, such as YouTube, Facebook, MySpace, Twitter, and Second Life® are rapidly emerging as popular sources of health information especially for teens and young adults. Social media marketing carries the advantages of low cost, rapid transmission through a wide community, and user interaction. Disadvantages include blind authorship, lack of source citation, and presentation of opinion as fact. Dermatologists and other health care providers should recognize the importance of social media websites and their potential usefulness for disseminating health information. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350269 Wed, 01 Apr 2009 04:00:00 +0100 2350269 http://www.medworm.com/index.php?rid=2350268&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508000971%2Fabstract%3Frss%3Dyes Survey research has been used to investigate a wide range of issues in dermatology. The proper use of survey design and analysis is critical for achieving reliable, accurate data and high impact in the medical literature. Here we describe the use of surveys from both a theoretical and practical standpoint. We provide recommendations for limiting error and producing interpretable results, followed by an outline for achieving publication. We conclude with a discussion of previous successful uses of survey studies in dermatologic literature. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350268 Wed, 01 Apr 2009 04:00:00 +0100 2350268 http://www.medworm.com/index.php?rid=2350267&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001046%2Fabstract%3Frss%3Dyes Human behavior is directly related to the development of various skin disease conditions and to the effectiveness of skin disease treatment regimens. Adherence research studies have demonstrated abysmal adherence to topical treatment of common skin disorders, opening new opportunities for improving skin disease treatment outcomes. The treatment of skin raises unique issues in environmental exposures, psychosocial human interactions, biology, and pharmacology. The resulting human behaviors and the potential to understand and modify those behaviors through behavioral research studies are exciting and promising. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350267 Wed, 01 Apr 2009 04:00:00 +0100 2350267 http://www.medworm.com/index.php?rid=2350266&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001058%2Fabstract%3Frss%3Dyes Behavioral studies of ultraviolet light exposure behavior have provided insight into motivations for tanning, which include not only the desire for a tanned appearance but also the physiologic response to ultraviolet light. Many frequent tanners continue to tan despite knowledge or personal experience of adverse consequences. Efforts to reduce tanning behavior need to account for the interplay between physiologic effects of tanning and psychosocial drives behind tanning behavior. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350266 Wed, 01 Apr 2009 04:00:00 +0100 2350266 http://www.medworm.com/index.php?rid=2350265&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001101%2Fabstract%3Frss%3Dyes This article focuses on health care disparities in dermatology, and invites providers to become agents of change. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350265 Wed, 01 Apr 2009 04:00:00 +0100 2350265 http://www.medworm.com/index.php?rid=2350264&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508000995%2Fabstract%3Frss%3Dyes This article discusses the importance of dermatologic public health and makes recommendations for better addressing this neglected topic. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350264 Wed, 01 Apr 2009 04:00:00 +0100 2350264 http://www.medworm.com/index.php?rid=2350263&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS073386350900014X%2Fabstract%3Frss%3Dyes Podcasts for this issue of Dermatologic Clinics are available at www.derm.theclinics.com (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350263 Wed, 01 Apr 2009 04:00:00 +0100 2350263 http://www.medworm.com/index.php?rid=2350262&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000138%2Fabstract%3Frss%3Dyes I dedicate this issue to my aunt and godmother Luciana Dellavalle who died during the production of this issue; I will always remember her delicious cooking, Tuscan proverbi, and deep religious faith. (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350262 Wed, 01 Apr 2009 04:00:00 +0100 2350262 http://www.medworm.com/index.php?rid=2350261&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863508001125%2Fabstract%3Frss%3Dyes This odyssey began with an email from Bruce Theirs asking me to consider editing a special issue of Dermatologic Clinics dedicated to dermatoepidemiology. We quickly decided to broaden the focus to include public health, making this the first issue of any Clinics of North America series specifically devoted to the topic of public health. I solicited potential articles from colleagues and members of the dermatoepidemiology list serve maintained by Martin Weinstock at Brown University (Providence, Rhode Island). Articles were submitted and peer reviews done in the fall of 2008. Reviewers were given the option of revealing or not revealing their identity to the authors and to our readers. I thank the peer reviewers listed below for their attention to detail, and for the hundreds of comments t... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350261 Wed, 01 Apr 2009 04:00:00 +0100 2350261 http://www.medworm.com/index.php?rid=2350260&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000084%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350260 Wed, 01 Apr 2009 04:00:00 +0100 2350260 http://www.medworm.com/index.php?rid=2350259&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.derm.theclinics.com%2Farticle%2FPIIS0733863509000072%2Fabstract%3Frss%3Dyes (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2350259 Wed, 01 Apr 2009 04:00:00 +0100 2350259 http://www.medworm.com/index.php?rid=2238942&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254649%26dopt%3DAbstract Authors: Dellavalle RP PMID: 19254649 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2238942 Fri, 06 Mar 2009 21:18:07 +0100 2238942 http://www.medworm.com/index.php?rid=2231417&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254649%26dopt%3DAbstract Authors: Dellavalle RP PMID: 19254649 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231417 Wed, 04 Mar 2009 16:51:37 +0100 2231417 http://www.medworm.com/index.php?rid=2231416&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254650%26dopt%3DAbstract Authors: Dellavalle RP PMID: 19254650 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231416 Wed, 04 Mar 2009 16:51:33 +0100 2231416 http://www.medworm.com/index.php?rid=2231415&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254651%26dopt%3DAbstract This article discusses the importance of dermatologic public health and makes recommendations for better addressing this neglected topic. PMID: 19254651 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231415 Wed, 04 Mar 2009 16:51:21 +0100 2231415 http://www.medworm.com/index.php?rid=2231414&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254652%26dopt%3DAbstract This article focuses on health care disparities in dermatology, and invites providers to become agents of change. PMID: 19254652 [PubMed - as supplied by publisher] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231414 Wed, 04 Mar 2009 16:51:04 +0100 2231414 http://www.medworm.com/index.php?rid=2231413&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254653%26dopt%3DAbstract Authors: Nolan BV, Feldman SR Behavioral studies of ultraviolet light exposure behavior have provided insight into motivations for tanning, which include not only the desire for a tanned appearance but also the physiologic response to ultraviolet light. Many frequent tanners continue to tan despite knowledge or personal experience of adverse consequences. Efforts to reduce tanning behavior need to account for the interplay between physiologic effects of tanning and psychosocial drives behind tanning behavior. PMID: 19254653 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231413 Wed, 04 Mar 2009 16:50:53 +0100 2231413 http://www.medworm.com/index.php?rid=2231412&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254654%26dopt%3DAbstract Authors: Nolan BV, Feldman SR Human behavior is directly related to the development of various skin disease conditions and to the effectiveness of skin disease treatment regimens. Adherence research studies have demonstrated abysmal adherence to topical treatment of common skin disorders, opening new opportunities for improving skin disease treatment outcomes. The treatment of skin raises unique issues in environmental exposures, psychosocial human interactions, biology, and pharmacology. The resulting human behaviors and the potential to understand and modify those behaviors through behavioral research studies are exciting and promising. PMID: 19254654 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231412 Wed, 04 Mar 2009 16:50:45 +0100 2231412 http://www.medworm.com/index.php?rid=2231411&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254655%26dopt%3DAbstract Authors: Asarch A, Chiu A, Kimball AB, Dellavalle RP Survey research has been used to investigate a wide range of issues in dermatology. The proper use of survey design and analysis is critical for achieving reliable, accurate data and high impact in the medical literature. Here we describe the use of surveys from both a theoretical and practical standpoint. We provide recommendations for limiting error and producing interpretable results, followed by an outline for achieving publication. We conclude with a discussion of previous successful uses of survey studies in dermatologic literature. PMID: 19254655 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231411 Wed, 04 Mar 2009 16:50:36 +0100 2231411 http://www.medworm.com/index.php?rid=2231410&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254656%26dopt%3DAbstract Authors: Vance K, Howe W, Dellavalle RP Social media websites, such as YouTube, Facebook, MySpace, Twitter, and Second Life(R) are rapidly emerging as popular sources of health information especially for teens and young adults. Social media marketing carries the advantages of low cost, rapid transmission through a wide community, and user interaction. Disadvantages include blind authorship, lack of source citation, and presentation of opinion as fact. Dermatologists and other health care providers should recognize the importance of social media websites and their potential usefulness for disseminating health information. PMID: 19254656 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231410 Wed, 04 Mar 2009 16:50:24 +0100 2231410 http://www.medworm.com/index.php?rid=2231409&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254657%26dopt%3DAbstract This article discusses observational studies that assess comorbidities in psoriasis, atopic dermatitis, vitiligo, and nonmelanoma skin cancer, and the likelihood of the observed associations and their clinical consequences. PMID: 19254657 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231409 Wed, 04 Mar 2009 16:50:17 +0100 2231409 http://www.medworm.com/index.php?rid=2231408&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254658%26dopt%3DAbstract This article analyzes these health risks and benefits and discusses pertinent issues surrounding indoor tanning, the role of sunless tanning products, and prudent sun exposure. PMID: 19254658 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231408 Wed, 04 Mar 2009 16:50:10 +0100 2231408 http://www.medworm.com/index.php?rid=2231407&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254659%26dopt%3DAbstract This article summarizes primary prevention strategies as well as management of patients already sensitized to nickel. PMID: 19254659 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231407 Wed, 04 Mar 2009 16:50:02 +0100 2231407 http://www.medworm.com/index.php?rid=2231406&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254660%26dopt%3DAbstract Authors: S Levin Y, Warshaw EM In this article, the authors summarize the published literature on the reliability and accuracy of teledermatology. The first section reports on the diagnostic reliability of teledermatology compared with face-to-face clinic consultation. In the second section, the authors report on the "intragroup" diagnostic agreement between either clinic dermatologists or teledermatologists. The third section discusses the diagnostic accuracy for those studies that include definitive histopathologic diagnosis. The last section summarizes the literature comparing clinical management decisions by clinic dermatologists to those made by teledermatologists. PMID: 19254660 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231406 Wed, 04 Mar 2009 16:49:54 +0100 2231406 http://www.medworm.com/index.php?rid=2231405&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254661%26dopt%3DAbstract This article describes recent developments in health care consumer activism including dermatology disease advocacy and efforts to improve dermatologist-patient interactions. PMID: 19254661 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231405 Wed, 04 Mar 2009 16:49:49 +0100 2231405 http://www.medworm.com/index.php?rid=2231404&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254662%26dopt%3DAbstract Authors: Naldi L, Chatenoud L A medical "registry" is a systematic collection of information from cases of a particular disease or other health relevant condition. Hospital-based registries primarily address prognosis, whereas population-based registries provide estimates of disease incidence. Opportunities to establish and investigate dermatology hospital- and population-based registries abound. PMID: 19254662 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231404 Wed, 04 Mar 2009 16:49:43 +0100 2231404 http://www.medworm.com/index.php?rid=2231403&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254663%26dopt%3DAbstract Authors: Simmons RN, Ellis JI, Dellavalle RP Many Internet resources for dermatologists benefit public health by providing education and information on the diagnosis and treatment of skin conditions. A variety of dermatology resources exist on the Web, but finding quality resources can be time-consuming. The authors provide a collection of high-quality, freely accessible, English-language Web sites that they have categorized as clinical, educational, or evidence-based medicine resources. They hope that this list of sources helps to meet the informational needs of dermatologists and promotes skin disease awareness and education. PMID: 19254663 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231403 Wed, 04 Mar 2009 16:49:34 +0100 2231403 http://www.medworm.com/index.php?rid=2231402&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254664%26dopt%3DAbstract This article provides instruction on how to effectively review a life sciences manuscript, particularly those in dermatology. PMID: 19254664 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231402 Wed, 04 Mar 2009 16:49:24 +0100 2231402 http://www.medworm.com/index.php?rid=2231401&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19254665%26dopt%3DAbstract This article reviews the research on, and examines the epidemiology and prevention of melanoma. Despite the great quantity of research into environmental and genetic causes, and the ease of diagnosis, incidence and mortality have risen in all developed countries during the last half century. Patient and physician education, and public health programs aimed at prevention, have had varied success. The authors conclude that, until we have better data on how to prevent skin cancer of all types, the best solutions are education of high-risk populations about skin self-evaluation in combination with physician examination to practice; and sun protection. PMID: 19254665 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=2231401 Wed, 04 Mar 2009 16:49:18 +0100 2231401 http://www.medworm.com/index.php?rid=1938001&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984362%26dopt%3DAbstract Authors: Del Rosso JQ PMID: 18984362 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1938001 Fri, 07 Nov 2008 10:40:04 +0100 1938001 http://www.medworm.com/index.php?rid=1938000&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984363%26dopt%3DAbstract This article reviews the anti-inflammatory and nonantimicrobial effects of antibiotics in acne and other diseases and examines issues relating to the emergence of decreased bacterial sensitivity to antibiotics and how these issues relate to clinical practice. It includes an overview of the inflammatory activities of some antibiotic agents and their potential for use in various dermatologic and nondermatologic diseases. It demonstrates that P acnes-resistant organisms may be associated with therapeutic failure in some patients with acne, and that the prudent use of antibiotics is necessary to ensure that we can continue to use these drugs to combat disease effectively. It concludes that there are treatment strategies that can effectively minimize the potential for development of resistant P... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1938000 Fri, 07 Nov 2008 10:40:01 +0100 1938000 http://www.medworm.com/index.php?rid=1937999&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984364%26dopt%3DAbstract Authors: Tanghetti EA, Popp KF Benzoyl peroxide (BPO) is the most widely used topical acne treatment, with significant antibacterial, antikeratolytic, and comedolytic activity. It has been shown to be extremely effective as monotherapy and in combination with antibiotics or retinoids for managing comedonal and inflammatory acne lesions. As numerous clinical studies have shown, the combination of BPO plus a topical antibiotic is not only more effective but also is often better tolerated than either agent alone. Unlike antibiotics, no bacterial resistance has been noted. Adding BPO to any long-term antibiotic regimen in acne is generally recommended to help reduce populations of drug-resistant variants. Although effective combinations of BPO and antibiotics or retinoids are used, BPO mon... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937999 Fri, 07 Nov 2008 10:39:58 +0100 1937999 http://www.medworm.com/index.php?rid=1937998&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984365%26dopt%3DAbstract This article discusses emerging patterns of resistance and the implications for clinical practice. Emergence of resistance is complicating decolonization of the skin and nares in patients infected with methicillin-resistant Staphylococcus aureus. In the setting of acne treatment, adding topical benzoyl peroxide has been shown to reduce the emergence of strains resistant to topical antibiotics. Other agents, such as zinc salts, are promising in this regard. This article discusses alternatives to antibiotics and mechanisms to stem the emergence of resistance. PMID: 18984365 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937998 Fri, 07 Nov 2008 10:39:56 +0100 1937998 http://www.medworm.com/index.php?rid=1937997&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984366%26dopt%3DAbstract Authors: Del Rosso JQ, Kim G Oral antibiotics are commonly used to treat acne vulgaris, primarily in patients presenting with moderate to severe facial or truncal disease severity. These agents are most appropriately used in combination with a topical regimen containing benzoyl peroxide and a topical retinoid. The most common oral antibiotics for treating acne vulgaris are the tetracycline derivatives, although macrolide agents such as erythromycin have also been used extensively. Over the past 4 decades, as the sensitivity of Propionibacterium acnes to several oral and topical antibiotics has decreased, the efficacy of oral tetracycline and erythromycin has markedly diminished, leading to increased use of doxycycline, minocycline, and other agents, such as trimethoprim/sulfamethoxazol... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937997 Fri, 07 Nov 2008 10:39:52 +0100 1937997 http://www.medworm.com/index.php?rid=1937996&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984367%26dopt%3DAbstract Authors: Elston DM Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) continues to make headlines because of large outbreaks in daycare centers and among members of athletic teams. CA-MRSA infections in children commonly lead to hospitalization. Life-threatening infections, such as necrotizing pneumonitis and brain abscess, can occur. The organism has crossed into hospitals and is now a common cause of hospital-acquired sepsis. Multidrug-resistant strains of MRSA are emerging in Asia, with the resistance based on either a novel gene cassette or a transmissible plasmid. The routine use of antibiotics in livestock seems to be contributing to the emergence of resistant organisms, and some of these have already produced human infection. Fortunately, most cutaneous CA-... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937996 Fri, 07 Nov 2008 10:39:49 +0100 1937996 http://www.medworm.com/index.php?rid=1937995&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984368%26dopt%3DAbstract Authors: Rosen T, Vandergriff T, Harting M Sexually transmissible diseases (STDs) remain a major health issue worldwide, with approximately 300 million new cases annually. STDs caused by bacteria can be treated with antibiotics, although the susceptibility pattern of many etiologic microbes has changed over the past few decades. Syphilis remains best managed with single-dose benzathine penicillin G. Other single-dose antibiotic regimens for lues are either associated with clinical failure or of uncertain dosage. However, single-dose azithromycin and ceftriaxone are suitable for chancroid. Lymphogranuloma venereum, reemergent as a cause of proctitis, is treated with prolonged courses of doxycycline or minocycline. Trimethoprim-sulfamethoxazole has replaced tetracycline derivatives as pr... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937995 Fri, 07 Nov 2008 10:39:46 +0100 1937995 http://www.medworm.com/index.php?rid=1937994&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984369%26dopt%3DAbstract Authors: Bhambri S, Bhambri A, Del Rosso JQ Atypical mycobacterial infections have been a cause of steadily growing infections over the past decades, especially in immunocompromised patients. They are classified by their ability to produce pigment, growth rate, and optimal temperature. Mycobacterium marinum, M kansasii, and M avium-intracellulare are examples of slow-growing mycobacteria. M fortuitum, M chelonei, and M abscessus are examples of rapidly growing mycobacteria. Atypical mycobacteria are ubiquitous in the environment. No specific treatment guidelines exist but a multidrug regimen combined with surgical modalities is often used for therapy. PMID: 18984369 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937994 Fri, 07 Nov 2008 10:39:43 +0100 1937994 http://www.medworm.com/index.php?rid=1937993&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984370%26dopt%3DAbstract Authors: Hirschmann JV Dermatologists can decrease unnecessary use of antimicrobial agents by avoiding them in situations wherein good evidence indicates that they are ineffective. Controlled trials indicate that antimicrobial agents are unhelpful in treating cutaneous abscesses, inflamed epidermal cysts, uninfected atopic eczema, and cutaneous ulcers caused by venous insufficiency or diabetes in the absence of significant contiguous soft-tissue inflammation. Prophylactic antibiotics are rarely appropriate for routine dermatologic surgery and are not indicated for patients who have prosthetic joints or vascular grafts. They are recommended only for a small group of patients who have abnormal cardiac valves, and then only with surgery involving clearly infected skin or soft-tissue. Topi... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937993 Fri, 07 Nov 2008 10:39:40 +0100 1937993 http://www.medworm.com/index.php?rid=1937992&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984371%26dopt%3DAbstract Authors: Bhatia N One fascinating element of medical dermatology is the diversity of available therapeutic agents, and dermatologists are well versed in applying the mechanism of action of a drug to modify a disease process. Oral antibiotics are the ideal example of pharmacologic agents that are effective against inflammatory processes and have obvious roles in infectious diseases. PMID: 18984371 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937992 Fri, 07 Nov 2008 10:39:37 +0100 1937992 http://www.medworm.com/index.php?rid=1937991&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18984372%26dopt%3DAbstract Authors: Del Rosso JQ Oral antibiotics are commonly prescribed by dermatologists in clinical practice. When prescribing an oral antibiotic, as with other systemic medications, it is important to consider potential interactions with other drugs, including over-the-counter medications. The most common drug interaction mechanisms that may lead to clinically significant sequelae are inhibition of GI drug absorption and alterations in drug metabolism. Tetracycline and quinolones undergo chelation interactions with many metal ions found in antacids and mineral supplements. Some macrolides, such as erythromycin, inhibit the hepatic metabolism of many other drugs, increasing the risk for toxicity. Rifampin increases the metabolism of many other drugs, thus predisposing to treatment failure. Dr... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1937991 Fri, 07 Nov 2008 10:39:34 +0100 1937991 http://www.medworm.com/index.php?rid=1805604&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793990%26dopt%3DAbstract Authors: Daudén E, Oñate MJ Calciphylaxis is defined by the presence of calcium deposits within the wall of small and medium-sized vessels. It is classically considered a life-threatening disease in patients with end-stage renal disease under dialysis. Clinically, it is characterized by the presence of painful plaques surrounded by a reticulate purpura that progresses to nonhealing ulcers, predominately in the lower limbs. It is associated with elevated parathyroid hormone levels and a dysregulation of the calcium/phosphate metabolism. In the absence of renal disease, normal parathyroid hormone levels, and calcium/phosphorus product, a good prognosis and the observation of similar calcium deposits associated with different conditions or even an epiphenomenon in diseases with ... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1805604 Fri, 19 Sep 2008 09:25:39 +0100 1805604 http://www.medworm.com/index.php?rid=1805603&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793991%26dopt%3DAbstract Authors: Herranz P, de Lucas R, Pérez-España L, Mayor M Lipodystrophy syndromes comprise a group of rare, heterogeneous disorders characterized by progressive loss of fat tissue, mainly from subcutaneous compartment and occasionally affecting visceral fat. Lipoatrophy may be partial, localized, or generalized. The latter cases are usually accompanied by metabolic-related disorders, including insulin resistance, diabetes mellitus, hyperlipemia, progressive hepatic disease and anabolic state. Treatment for lipodystrophy has increased interest in recent years because a new lipoatrophic population-patients who have HIV-associated lipodystrophy-is much more numerous than the whole number of patients affected by classic lipodystrophy entities. PMID: 18793991 [PubMed - in proces... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1805603 Fri, 19 Sep 2008 09:25:34 +0100 1805603 http://www.medworm.com/index.php?rid=1802244&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793972%26dopt%3DAbstract Authors: Requena L PMID: 18793972 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802244 Thu, 18 Sep 2008 09:44:31 +0100 1802244 http://www.medworm.com/index.php?rid=1802243&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793973%26dopt%3DAbstract Authors: Segura S, Requena L The panniculitides comprise a group of heterogeneous inflammatory diseases that involve the subcutaneous fat. Histopathologic study is required for the specific diagnosis of these disorders, because different panniculitides usually show the same clinical appearance, which consists of erythematous nodules on the lower extremities. The histopathologic study of panniculitis is difficult, however, because of an inadequate clinicopathologic correlation and the changing evolutive nature of the lesions. Some cutaneous lymphomas may simulate panniculitis, both from clinical and histopathologic points of view, and for that reason are included in this article despite the fact that they are not inflammatory processes but authentic lymphocytic neoplasms involving subcu... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802243 Thu, 18 Sep 2008 09:44:27 +0100 1802243 http://www.medworm.com/index.php?rid=1802242&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793974%26dopt%3DAbstract Authors: Requena L, Yus ES Erythema nodosum is the most frequent clinicopathologic variant of panniculitis. The process is a cutaneous reaction that may be associated with a wide variety of disorders, including infections, sarcoidosis, rheumatologic diseases, inflammatory bowel diseases, medications, autoimmune disorders, pregnancy, and malignancies. Histopathologically, erythema nodosum is the stereotypical example of a mostly septal panniculitis with no vasculitis. The composition of the inflammatory infiltrate in the septa varies with age of the lesion. Treatment of erythema nodosum should be directed to the underlying associated condition, if identified. PMID: 18793974 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802242 Thu, 18 Sep 2008 09:44:24 +0100 1802242 http://www.medworm.com/index.php?rid=1802241&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793975%26dopt%3DAbstract Authors: Mascaró JM, Baselga E Erythema induratum of Bazin is a chronic, nodular eruption that usually occurs on the lower legs of young women. It has been regarded as a manifestation of tuberculin hypersensitivity, a type of tuberculid occurring on the legs, whereas nodular vasculitis represents the nontuberculous counterpart. The number of reports of erythema induratum of Bazin is decreasing in most developed countries in accordance with the decreased incidence of tuberculosis. The etiopathogenesis of erythema induratum of Bazin and its relation to tuberculosis are still controversial, because mycobacteria cannot be cultured from the skin lesions. Most authors currently consider erythema induratum of Bazin (nodular vasculitis) a multifactorial disorder with many different causes... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802241 Thu, 18 Sep 2008 09:44:22 +0100 1802241 http://www.medworm.com/index.php?rid=1802240&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793976%26dopt%3DAbstract Authors: Valverde R, Rosales B, Ortiz-de Frutos FJ, Rodríguez-Peralto JL, Ortiz-Romero PL Alpha-1-antitrypsin deficiency is a congenital error of metabolism linked to pulmonary (emphysema) and liver (cirrhosis) disease. Since 1972, panniculitis has been associated with this deficiency, initially related to Weber-Christian syndrome and finally as a differentiated entity. Clinical manifestations typically consist of wide nodular lesions on the trunk and proximal extremities that evolve to ulceration and drainage. Histopathologically it presents as a mixed septal-lobular panniculitis pattern with some typical findings referred. Differential diagnosis from other types of panniculitis and neutrophilic dermatosis must be established. Different treatments, including tetracyclines, dapson... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802240 Thu, 18 Sep 2008 09:44:18 +0100 1802240 http://www.medworm.com/index.php?rid=1802239&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793977%26dopt%3DAbstract This article reviews the salient clinicopathologic features and treatment of lupus erythematosus panniculitis, with special emphasis on the histopathologic features. PMID: 18793977 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802239 Thu, 18 Sep 2008 09:44:15 +0100 1802239 http://www.medworm.com/index.php?rid=1802238&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793978%26dopt%3DAbstract Authors: García-Romero D, Vanaclocha F Pancreatic panniculitis is an uncommon complication of pancreatic disease, most frequently pancreatitis and pancreatic carcinoma. The pathogenesis of the process remains unknown, but possibly the release of pancreatic enzymes may induce permeability of the microcirculation and cause fat necrosis. Clinically, pancreatic panniculitis presents with tender, ill-defined, red-brown nodules in the lower extremities that may ulcerate and drain an oily substance and usually precedes pancreatic disease. The histopathologic picture consists of a mostly lobular panniculitis without vasculitis, with the presence of the typical ghost cells that correspond to necrotic and calcified adipocytes. Treatment should be directed at the underlying pancreatic diseas... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802238 Thu, 18 Sep 2008 09:44:12 +0100 1802238 http://www.medworm.com/index.php?rid=1802237&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793979%26dopt%3DAbstract Authors: Delgado-Jimenez Y, Fraga J, García-Díez A Infective panniculitides are infections of the subcutaneous fat induced by any kind of micro-organism. They have rarely been considered as an entity within the spectrum of the panniculitis. Because of the increase in the immunosuppressive population, cutaneous infections' incidence is growing and atypical clinical presentations can be found. In this article, we analyze the etiology, clinical picture, histopathologic findings, diagnostics tools, and treatment of the more relevant infective panniculitis. We divide them according to the causative micro-organisms in bacterial, mycobacterial, fungal, and viral panniculitis. PMID: 18793979 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802237 Thu, 18 Sep 2008 09:44:08 +0100 1802237 http://www.medworm.com/index.php?rid=1802236&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793980%26dopt%3DAbstract Authors: Moreno A, Marcoval J, Peyri J Traumatic panniculitis refers to changes in the subcutaneous fat related to physical or chemical agents. The clinical picture of traumatic panniculitis is nonspecific. Cutaneous lesions are indurated, warm, red, subcutaneous plaques or nodules not necessary related to the intensity of the injury. The histologic picture includes fat microcysts surrounded by histiocytes, collections of foam cells, and inflammatory cells. Late lesions may show fibrosis, lipomembranous changes, or dystrophic calcic deposits. Traumatic panniculitis is usually a self-limiting disorder and requires only symptomatic treatment. PMID: 18793980 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802236 Thu, 18 Sep 2008 09:44:03 +0100 1802236 http://www.medworm.com/index.php?rid=1802235&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793981%26dopt%3DAbstract Authors: Quesada-Cortés A, Campos-Muñoz L, Díaz-Díaz RM, Casado-Jiménez M Cold panniculitis has been described in children and young women following cold exposure. Histopathologically, cold panniculitis shows a mostly lobular panniculitis, which consists of an infiltrate of lymphocytes and histiocytes in the fat lobules. Usually, the dermis shows a superficial and deep perivascular infiltrate mostly composed of lymphocytes, with no vasculitis. Inflammation is most intense at the dermal-subcutaneous junction. Differential diagnosis of cold panniculitis should be established with subcutaneous fat necrosis of the newborn, sclerema neonatorum, poststeroid panniculitis, chilblains, and frostbites. PMID: 18793981 [PubMed - in process] (Source: Dermatologic Clinic... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802235 Thu, 18 Sep 2008 09:44:00 +0100 1802235 http://www.medworm.com/index.php?rid=1802234&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793982%26dopt%3DAbstract This article reviews in detail the specific types of panniculitis of the newborn and discusses the pediatric aspects of the panniculitis that is often seen in adults. PMID: 18793982 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802234 Thu, 18 Sep 2008 09:43:53 +0100 1802234 http://www.medworm.com/index.php?rid=1802233&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793983%26dopt%3DAbstract Authors: Requena C, Sanmartín O, Requena L Sclerosing panniculitis is a chronic panniculitis characterized by skin induration and hyperpigmentation of one or both legs that often occurs in patients who have venous insufficiency. The indurated plaques are often painful and the legs frequently have a characteristic "inverted wine bottle" appearance. Histopathology is characterized by mostly lobular panniculitis with necrosis of fat and without vasculitis, and in fully developed lesions by septal sclerosis and membranocystic changes. Treatment of sclerosing panniculitis includes compression therapy with graded stockings and anabolic steroids. PMID: 18793983 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802233 Thu, 18 Sep 2008 09:43:51 +0100 1802233 http://www.medworm.com/index.php?rid=1802232&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793984%26dopt%3DAbstract Authors: Requena L, Ferrándiz C Sclerosing postirradiation panniculitis is an unusual variant of panniculitis that appears as a complication of megavoltage radiotherapy. Most patient are women with a history of breast cancer who develop nodular lesions on the anterior chest skin several months after receiving megavoltage therapy for breast carcinoma. Sclerosing postirradiation panniculitis is an unusual cutaneous complication of megavoltage radiotherapy that should be distinguished from subcutaneous metastatic disease, cellulitis, and connective tissue diseases involving the subcutaneous fat. The differential diagnosis can be established on the basis of the characteristic histopathologic features. PMID: 18793984 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802232 Thu, 18 Sep 2008 09:43:46 +0100 1802232 http://www.medworm.com/index.php?rid=1802231&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793985%26dopt%3DAbstract Authors: Segura S, Pujol RM Lipomembranous fat necrosis (LMFN) is a special subtype of fat necrosis characterized by the development of pseudocystic cavities lined with hyaline-crenulated membranes. This regressive degeneration or localized destruction of adipose tissue has been reported as a focal phenomenon or, rarely, as an extensive one in several pathologic conditions of the subcutaneous tissue. LMFN is frequently observed in patients who have chronic sclerotic infiltrated plaques or tender subcutaneous nodules on the lower extremities, often diagnosed as lipodermatosclerosis. There is increasing evidence that it is a morphologic feature that cannot be related to any particular clinical setting, however. Multiple local or systemic events causing a compromise in the blood supply of... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802231 Thu, 18 Sep 2008 09:43:43 +0100 1802231 http://www.medworm.com/index.php?rid=1802230&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793986%26dopt%3DAbstract Authors: Sanmartín O, Requena C, Requena L Factitial panniculitides are subcutaneous tissue injuries produced by external agents or actions. In most cases, factitial panniculitis is caused by self-injection of different substances. Factitial panniculitis can also appear as an iatrogenic consequence of injections of drugs or immunization agents. The clinical features of factitial panniculitis are quite variable, depending on the inciting agent. The histopathology of factitial panniculitis usually shows a pattern of an acute lobular panniculitis associated with fat necrosis and an abundant inflammatory infiltrate predominantly composed of neutrophils. PMID: 18793986 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802230 Thu, 18 Sep 2008 09:43:39 +0100 1802230 http://www.medworm.com/index.php?rid=1802229&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793987%26dopt%3DAbstract Authors: Gallardo F, Pujol RM The concept of subcutaneous T-cell lymphoma defines a reduced group of primary cutaneous lymphomas characterized morphologically by a prominent or exclusive subcutaneous tissue involvement. Subcutaneous panniculitic-like T-cell lymphoma is a rare subtype of primary cutaneous T-cell lymphoma clinically mimicking panniculitis. The clinical course is usually protracted with recurrent cutaneous lesions but rarely with early extracutaneous dissemination. The clinical, histopathologic, immunophenotypic, and evolutive features of this heterogeneous and rare group of primary cutaneous lymphomas are reviewed. PMID: 18793987 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802229 Thu, 18 Sep 2008 09:43:36 +0100 1802229 http://www.medworm.com/index.php?rid=1802228&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793988%26dopt%3DAbstract This article reviews subcutaneous Sweet syndrome, which is a rare idiopathic panniculitis characterized by a dense neutrophilic infiltrate in the subcutis and is often related to hematologic malignancies. The relationship of subcutaneous Sweet syndrome and erythema nodosum is discussed as well as the differential diagnosis with other neutrophilic panniculitis. PMID: 18793988 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802228 Thu, 18 Sep 2008 09:43:32 +0100 1802228 http://www.medworm.com/index.php?rid=1802227&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18793989%26dopt%3DAbstract Authors: Marcoval J, Moreno A, Mañá J, Peyri J Subcutaneous sarcoidosis has been reported to occur in 1.4% to 6% of patients with systemic sarcoidosis. Most reported cases are in women, most often in their fifth and sixth decades, and appear as multiple, asymptomatic, hardly indurated subcutaneous nodules without changes in the overlying epidermis. The lesions are characteristically located in the upper extremities, mainly in the forearms, and usually are bilateral and asymmetric. In most cases the lesions appear at the beginning of systemic sarcoidosis and are not associated with chronic fibrotic disease. Histopathologically, sarcoidosis is characterized by noncaseating naked granulomas involving fat lobules, with minimal to no septal involvement. PMID: 18793989 [PubMed ... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1802227 Thu, 18 Sep 2008 09:43:29 +0100 1802227 http://www.medworm.com/index.php?rid=1699818&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555947%26dopt%3DAbstract Authors: Sadick NS PMID: 18555947 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1699818 Tue, 01 Jul 2008 04:00:00 +0100 1699818 http://www.medworm.com/index.php?rid=1525153&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555947%26dopt%3DAbstract Authors: Sadick NS PMID: 18555947 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525153 Wed, 18 Jun 2008 20:15:36 +0100 1525153 http://www.medworm.com/index.php?rid=1525152&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555948%26dopt%3DAbstract This article discusses the key elements that should be considered to make this venture successful. PMID: 18555948 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525152 Wed, 18 Jun 2008 20:15:34 +0100 1525152 http://www.medworm.com/index.php?rid=1525151&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555949%26dopt%3DAbstract This article discusses the importance of the dermatologist-run spa, as well as the author's ideas and experience with opening and running a medical spa or medi-spa. PMID: 18555949 [PubMed - as supplied by publisher] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525151 Wed, 18 Jun 2008 20:15:31 +0100 1525151 http://www.medworm.com/index.php?rid=1525150&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555950%26dopt%3DAbstract This article focuses on the more recent technologic advancements in rejuvenation. PMID: 18555950 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525150 Wed, 18 Jun 2008 20:15:28 +0100 1525150 http://www.medworm.com/index.php?rid=1525149&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555951%26dopt%3DAbstract Authors: Taub AF Medical spas' menus of services vary widely and depend greatly on the medical director or owner's experience and predilection. Core services include: microdermabrasion, mild chemical peels, medical facials, laser hair removal, photorejuvenation, botulinum toxin, and injectable fillers. Common procedures include cellulite reduction, tissue tightening, and acne treatments. Less common procedures that are more likely to be performed in medical spas with direct on-site daily involvement of the medical director include: laser resurfacing, laser-assisted lipoplasty, sclerotherapy, photodynamic therapy, and cosmetic surgery. Multisite spas often use multi-platform devices to assist with uniformity in menu offerings and training. PMID: 18555951 [PubMed - in process] (Sourc... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525149 Wed, 18 Jun 2008 20:15:25 +0100 1525149 http://www.medworm.com/index.php?rid=1525148&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555952%26dopt%3DAbstract This article describes the four parameters that make up the BSTI, focusing on basic science and defining characteristics and summarizing the 16 skin-type variations. PMID: 18555952 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525148 Wed, 18 Jun 2008 20:15:19 +0100 1525148 http://www.medworm.com/index.php?rid=1525147&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555953%26dopt%3DAbstract This article explains the legalities of selling retail products in the medical practice and how to sell effectively and profitably. It additionally explains how this will help retain clients and provides advice on how to encourage those clients to refer their friends with confidence. PMID: 18555953 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525147 Wed, 18 Jun 2008 20:15:16 +0100 1525147 http://www.medworm.com/index.php?rid=1525146&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555954%26dopt%3DAbstract Authors: Goldberg DJ A better understanding of the medical-legal considerations of the medical spa environment plays a role in promoting a successful medical spa. The medical spa setting is ideal for the performance of procedures that are incision-less, provide minimal discomfort, create little to no skin wound, and are performed in less than one hour. The procedures that fit this model include those that promote antiaging, those that lead to rhytid treatment, and hair removal. PMID: 18555954 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525146 Wed, 18 Jun 2008 20:15:14 +0100 1525146 http://www.medworm.com/index.php?rid=1525145&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555955%26dopt%3DAbstract Authors: Sadick NS, Dinkes A, Oskin L Medical spas are different. We are not just selling medical and dermatology services; we are offering clients viable new solutions to their skin care, body care, and hair care challenges. Traditional medical marketing becomes blurred today, as the expansion and acceptance of medical spas helps you to effectively compete with traditional skin care clinics, salons, and spas, while offering more therapeutic treatments from professionally licensed doctors, nurses, aestheticians, massage therapists, spa professionals, and medical practitioners. We recommend that you make the choice to successfully and competitively become a market-driven medical spa with an annual strategic plan, rather than an operationally driven business. PMID: 18555955 [PubMed -... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525145 Wed, 18 Jun 2008 20:15:10 +0100 1525145 http://www.medworm.com/index.php?rid=1525144&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18555956%26dopt%3DAbstract This article details the past, present, and future of spa dermatology and discusses the implications for dermatologists. PMID: 18555956 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1525144 Wed, 18 Jun 2008 20:15:07 +0100 1525144 http://www.medworm.com/index.php?rid=1474526&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18506459%26dopt%3DAbstract In conclusion, we present a well documented, rare case of pemphigoid gestationis with maternal transfer to the infant. A historical and epidemiological review of this rare blistering disorder is discussed along with current theories on pathogenic and immunologic mechanisms. PMID: 18506459 [PubMed - as supplied by publisher] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1474526 Wed, 28 May 2008 04:00:00 +0100 1474526 http://www.medworm.com/index.php?rid=1313781&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18346549%26dopt%3DAbstract Authors: Lotti T PMID: 18346549 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1313781 Wed, 19 Mar 2008 19:58:20 +0100 1313781 http://www.medworm.com/index.php?rid=1313780&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18346550%26dopt%3DAbstract Authors: Lotti T, Handog EB, Hercogová J, Ramos-E-Silva M The technical advances of the last century changed the understanding of the science of cutaneous physiology and pathology and the role of the dermatologist. The major challenges the international dermatologic community faces today are the lack of a common, logical, and accepted language within the specialty; long-accepted but questionable policies to advance academic careers; and the marginalization of dermatology. Methods for communicating and circulating data and ideas also have changed radically. The distribution of knowledge and essential/practical tools in different regions of the world is inequitable, and developing countries must cope with the challenges of high-impact skin diseases. PMID: 18346550 [PubMed - in p... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1313780 Wed, 19 Mar 2008 19:58:17 +0100 1313780 http://www.medworm.com/index.php?rid=1313779&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18346551%26dopt%3DAbstract This article focuses on the varied presentations of the infection, earning the title the "great imitator." The article also tackles other significant concerns regarding this malady. PMID: 18346551 [PubMed - in process] (Source: Dermatologic Clinics) Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1313779 Wed, 19 Mar 2008 19:58:14 +0100 1313779 http://www.medworm.com/index.php?rid=1313778&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18346552%26dopt%3DAbstract Authors: Murrell DF, Handog EB Little has been written about the various types and availability of international exchange programs in dermatology. These opportunities comprise medical student electives, mentorships for dermatology residents, international residencies, and clinical and research fellowships. For qualified dermatologists, there are opportunities for teaching and volunteering in emerging countries and career-development visiting fellowships to academic centers and private practices to learn specific techniques or to focus on particular areas. Exchange programs in dermatology, although minimal now, soon may be accessible to most dermatologists worldwide, thereby promoting the advancement of scientific and clinical dermatologic information. The tables summarize funding sourc... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1313778 Wed, 19 Mar 2008 19:58:12 +0100 1313778 http://www.medworm.com/index.php?rid=1313777&cid=s_33221_12_f&fid=33221&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18346553%26dopt%3DAbstract Authors: Honrado ER, Tallo V, Balis AC, Chan GP, Cho SN The success of current World Health Organization (WHO) key strategy for leprosy elimination (ie, multidrug therapy [MDT] regimen) depends largely on the efficiency of health care delivery services and patient compliance. A high rate of noncompliance with this regimen has serious implications for the leprosy control program because it can set the stage for the emergence of drug resistance, eventually resulting in treatment failure and failure of the program. A community-based descriptive study using pretested interviews conducted in 12 leprosy endemic areas in Cebu, Philippines, showed that the noncompliance rate with the WHO-MDT regimen among 233 study subjects was 30%. The causes of noncompliance are drug-related, health care pro... Dermatologic Clinics journals http://www.medworm.com/rss/comments.php?id=1313777 Wed, 19 Mar 2008 19:58:09 +0100 1313777