MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'European Archives of Oto-Rhino-Laryngology' source. Wed, 08 Feb 2012 15:44:31 +0100 http://www.medworm.com/index.php?rid=5667800&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7h86pu2q31620302%2F This study aimed to assess and compare the prevalence of aphysiologic performance on computerized dynamic posturography (CDP) in patients with the potential for secondary gain using a retrospective review of two groups of patients: work-related patients referred for dizziness and/or imbalance (Group 1) were compared against a group of patients with complaints of dizziness or imbalance, who had no history of work-related injury, or litigation procedures (Group 2). CDP and videonystagmography (VNG) were carried out in all patients. The Sensory Organization Test summaries were scored as normal, aphysiologic, or vestibular using the scoring method published by Cevette et al. in Otolaryngol Head Neck Surg 112:676–688 (1995). 24 out of 88 (27%) patients had aphysiologic CDP in Group 1 an... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5667800 Fri, 03 Feb 2012 17:12:23 +0100 5667800 http://www.medworm.com/index.php?rid=5667801&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6772536384980472%2F The objective of this study is to report the vocal characteristics of patients with type 2 diabetes mellitus in relation to disease duration, glycemic control, and neuropathy. This is a prospective study. The setting is institutional setting. A total of 82 patients were recruited for this study, and a healthy control group matched according to age and gender was recruited. Subjects underwent acoustic analysis and perceptual evaluation using the GRABS classification where G stands for grading, R for roughness, A for asthenia, B for breathiness, and S for straining using a scale of 0–3 where o stands for normal and three for severe deviation from normal. There was no significant difference in any of the acoustic variables between diabetic patients and control. There was no significan... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5667801 Thu, 02 Feb 2012 18:15:45 +0100 5667801 http://www.medworm.com/index.php?rid=5667802&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl3734x6053454343%2F Abstract  Long-term oncological and functional results from a retrospective study on 469 patients over a 10-year period of subtotal laryngectomies (SL), 399 supracricoid partial laryngectomies (SCL) and 70 supratracheal partial laryngectomies (STL) are presented. The mean follow-up time was 97 months (range 60–165 months). Acute complications, types and rates of late sequelae, functional results, 2-year post-operative scores of laryngeal function and quality of life are reported. The observed long-term results were: SCL, 5-year overall and disease-free survival: 95.6, and 90.9%, respectively; 2-year post-operative laryngeal function preservation: 95.7%; STL, 5-year overall and disease-free survival: 80 and 72.9%, respectively; 2-year post-operative laryngeal fun... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5667802 Thu, 02 Feb 2012 18:15:41 +0100 5667802 http://www.medworm.com/index.php?rid=5660458&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg330467522203587%2F Abstract  To evaluate the prevalence of thyroid FDG-PET/CT incidentalomas and the risk of malignancy in focal findings. A retrospective study of 3,062 PET scans was performed between 05/2006 and 09/2009. Prevalence of thyroid incidentalomas, risk of malignancy and correlation between standard uptake value (SUV) and cancer risk were analysed. The overall prevalence of thyroid incidentalomas was 2.4%. 71% showed a focal and 29% a diffuse uptake. In the focal uptake group, the diagnosis was clarified in 79% with cytology/histology. In 23.8% of the patients with a focal uptake, a malignant lesion was found. Diffuse uptake was predominantly associated with autoimmune thyroiditis. There was no statistically significant difference in the SUVmax between benign and malignant focal le... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5660458 Wed, 01 Feb 2012 17:12:48 +0100 5660458 http://www.medworm.com/index.php?rid=5660461&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp13326n85h3t7022%2F Abstract  Obstructive sleep apnea (OSA) is a common sleep disorder which can result in mood problems. The aim of this study was to evaluate the severity of depression and anxiety symptoms as the most prevalent psychological disturbances present in different severity of OSA. We performed a cross-sectional study of 685 recently diagnosed sleep-disordered patients, over the age of 18, referred to Noor Sleep Lab from August 2008 to November 2010. The participants filled the Beck depression inventory-II (BDI-II) and the Beck anxiety inventory (BAI) to assess the depression and anxiety symptoms. We collected other characteristics of subjects such as age, sex, body mass index (BMI) and Epworth sleepiness scale (ESS). Apnea hypopnea index (AHI) was determined by an overnight polyso... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5660461 Wed, 01 Feb 2012 17:12:47 +0100 5660461 http://www.medworm.com/index.php?rid=5660460&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp61478166gh74887%2F Abstract  The electronystagmographical analysis of the eye movements provoked by caloric stimulation is an important method in the evaluation and topical diagnostic procedure of several vestibular lesions. The aim of the study was to compare the electronystagmographical results of caloric response in several vestibular disorders. The patients were divided into five groups: right and left unilateral and bilateral peripheral lesions, central vestibular dysfunction, and normal vestibular function. In the normal vestibular system group the average caloric nystagmus SPV in normal vestibular system was 17.4°/s. In the peripheral lesion groups the average slow phase velocities are decreased in the affected side, as we expected. In the compensated vestibular lesion the average ASP... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5660460 Wed, 01 Feb 2012 17:12:47 +0100 5660460 http://www.medworm.com/index.php?rid=5660459&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0g0rqt1612g75117%2F The objective of this study is to evaluate the incidence of pathologic gastroesophageal reflux in laryngectomized patient with phonatory prosthesis, analyzing potential related problems and appraising, at the same time, the effectiveness of a therapeutic protocol. A retrospective study was conducted on 43 phonatory prosthesis patients who had problems with regard to recurrent tracheoesophageal granulations, the need of frequent prosthesis replacement, within a 3-month period, and unsatisfactory vocal results. Such patients underwent physical examination of the fistula region and of the neopharynx and were submitted to esophagogastroduodenoscopy. Moreover the group of patients underwent a therapeutic protocol and were re-evaluated posttreatment, examining fistula region both on the tr... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5660459 Wed, 01 Feb 2012 17:12:47 +0100 5660459 http://www.medworm.com/index.php?rid=5660462&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe5675k1517k55093%2F This study examined efficacy of the innate immune defence via the mannose binding lectin (MBL) in a cohort of 55 dystonic patients prospectively referred to the clinic with laryngeal mucosal complaints, who were placed on local steroids (budesonid inhaler, 400 μg 2 times daily) and antihistamines (fexofenadin 180 mg mostly 3 times daily) with adjuvant lifestyle corrections. Treatment efficacy of the larynx was assessed based on mucosal findings of the vocal folds examined with phonatory function studies (PhFS) comprising simultaneous high-speed digital images, kymography, electroglottography and voice acoustics combined with a visual score of arytenoids oedema, as these measures are indicative of the magnitude of laryngitis. Lactose and gluten intolerance and immunological... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5660462 Tue, 31 Jan 2012 07:05:19 +0100 5660462 http://www.medworm.com/index.php?rid=5648887&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fev01425341834k76%2F Conclusion  The implants were fairly beneficial in restoring hearing and improving communication abilities although many reprogramming sessions have been required. The hurdle in programming was the need of frequent adjustments due to the physiologic variations in electrical discharges and neural conduction, besides the changes in the impedances. Patients diagnosed with superficial siderosis may achieve limited results in speech perception scores due to both cochlear and retrocochlear reasons. Careful counseling about the results must be given to the patients and their families before the cochlear implantation indication. Content Type Journal ArticleCategory Case ReportPages 1-9DOI 10.1007/s00405-011-1850-1Authors Aline Gomes Bittencourt, Department of Otolaryngolog... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5648887 Wed, 25 Jan 2012 18:14:53 +0100 5648887 http://www.medworm.com/index.php?rid=5638964&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpxq628121u2623w8%2F Abstract  Salvage laryngectomy carries a high risk of post-operative infection with reported rates of 40–61%. The purpose of this study was to analyse infections in our own patients and review the potential impact of our current antibiotic prophylaxis (AP). A retrospective analysis of infection in 26 consecutive patients between 2000 and 2010 undergoing salvage total laryngectomy (SL) following recurrent laryngeal cancer after failed radiotherapy or chemo-radiation was undertaken. The antibiotic prophylaxis was intravenous teicoplanin, cefuroxime and metronidazole at induction and for the following 24 h. Infection was defined by Tabet and Johnson’s grade 5, categorized as pharyngocutaneous fistula. Fifteen patients (58%) developed a post-operative wound infection, ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5638964 Tue, 24 Jan 2012 12:27:15 +0100 5638964 http://www.medworm.com/index.php?rid=5638965&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn244188g018170h2%2F Abstract  Evaluation of the severity of disease and the effectiveness of operative treatment is commonly done by registering pre- and postoperative symptoms. During the preceding decade, greater awareness has focused not only on the symptoms but also on patients’ quality of life (QoL). The aim of the study was to determine the effect of septoplasty, as measured by generic and disease-specific QoL questionnaires. The generic 15D and disease-specific SNOT-22 questionnaires were given to patients before the operation and 6 months after the operation. Data analysis consisted originally of 188 septoplasty patients. One-hundred and twenty-six patients (67%) answered the SNOT-22 questions, and in the 15D, the response rate was 76%. In the post-operative SNOT-22, the need to... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5638965 Tue, 24 Jan 2012 12:27:14 +0100 5638965 http://www.medworm.com/index.php?rid=5638967&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm55711717824160x%2F In this study, time-dependent cytotoxic effects of cigarette and carbon papers used in repairing small traumatic TM perforations were investigated in vitro by using MTT test. And also adhesion and spreading of cells over disk surface were observed by SEM. Cytotoxicity test carried out by MTT analysis on leakage products collected from two types of paper patches at the end of 24 and 48 h revealed no cytotoxicity (P > 0.05). In SEM studies, it was observed that cells started to proliferate over disk surface as a result of 48-h incubation, and SEM revealed that the cell proliferation over cigarette paper was more compared to the one over carbon paper. We believe that this is the first study where biocompatibility and adhesion features of carbon and cigarette paper have ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5638967 Tue, 24 Jan 2012 07:28:21 +0100 5638967 http://www.medworm.com/index.php?rid=5638966&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F656952022g321338%2F Abstract  Eosinophilia occurs in up to 75–90% of nasal polyps in Caucasians. The chemokines eotaxin and RANTES increase eosinophil recruitment, activation, and survival, and these chemokines are significantly expressed in nasal polyps. We hypothesized that eotaxin and RANTES plasma levels might be correlated with disease severity. We compared the eotaxin and RANTES plasma levels in 20 Taiwanese patients with chronic rhinosinusitis and nasal polyps and 20 Taiwanese healthy controls. Eotaxin and RANTES plasma levels were measured by ELISA and disease severity was scored by CT scans. Compared to controls, patients with nasal polyps had significantly elevated plasma levels of eotaxin and RANTES and increased peripheral blood eosinophils (p < 0.001). Eotaxin plasma... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5638966 Tue, 24 Jan 2012 07:28:21 +0100 5638966 http://www.medworm.com/index.php?rid=5638968&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv75675971t32l335%2F Abstract  Direct laryngoscopy is the most predominantly used technique in laryngology, with the fulcrum-based laryngoscope serving as the most popular instrument. The purpose of this study was to accurately calculate and measure the pressure acting on the laryngopharynx and the tongue base during microlaryngoscopy. The relationship between postoperative throat pain and the time and pressure applied during microlaryngoscopy were also investigated. Fifty patients undergoing microlaryngeal surgery were included in this prospective study. Parameters that may help predict difficult laryngeal exposure were measured in the patients before microlaryngoscopy. Using static equilibrium and the law of the lever, the pressure acting on the laryngopharynx and the tongue base were calcula... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5638968 Tue, 24 Jan 2012 07:28:19 +0100 5638968 http://www.medworm.com/index.php?rid=5638969&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc1840181666x2784%2F The objectives of the study were to analyze the clinical features of inverted papillomas (IP) associated with malignancy and to evaluate the correlation of tumor stage, survival and histolologic features. We conducted a retrospective review of 18 IP associated with malignancy patients. In addition, we compared histopathologic characteristics (tumor differentiation and malignant cell proportion) with clinical outcomes. Eleven of the tumors were present on the nasal cavity and 7 on the maxillary sinus. The rates of synchronous and metachronous malignancy were 10.1 and 1.1%, respectively. The disease-free survival rate was 83.3%. The tumors were staged as T1 (5/18), T2 (2/18), T3 (8/18), and T4 (3/18). According to the percentage of the malignant cell in the entire tumor tissue, 4 patie... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5638969 Tue, 24 Jan 2012 07:28:18 +0100 5638969 http://www.medworm.com/index.php?rid=5620706&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2026u3887g705257%2F Abstract  The aim of the study is to compare audiological results in patients treated surgically with either an open or closed cavity mastoidectomy. A prospective review of a single surgeon’s case series based at two district general hospitals. All patients with 1-year post-operative hearing results following an open or closed cavity mastoid surgery were included. Outcome measured included the preoperative and postoperative air-bone gap (ABG). Belfast rule of thumb was used to assess the benefit from middle ear surgery. A total of 128 patients were identified from the database with 1 year post-operative hearing results. Sixty-three patients had undergone an open cavity mastoidectomy and 65 had a closed cavity mastoidectomy. The mean post-operative ABG in patients wit... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5620706 Tue, 17 Jan 2012 07:18:54 +0100 5620706 http://www.medworm.com/index.php?rid=5620709&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg081546x72564538%2F Abstract  The aim was to evaluate the efficacy of [18F]-2-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) in evaluating metastasis of head and neck squamous cell carcinoma (HNSCC) to the cervical lymph nodes, with specific attention to the efficacy in regard to clinically negative necks. This was a retrospective review of 243 patients with HNSCC between years 2005 and 2007 treated at a comprehensive cancer care institution who underwent pre-operative PET/CT and neck dissection with either an N0 (112 patients) or N+ (131 patients) clinical nodal status. PET/CT findings were correlated with histopathological results of surgical specimens. A majority of the primary sites were oral cavity and oropharynx (70%), followed by larynx, unknown primary and ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5620709 Tue, 17 Jan 2012 07:18:53 +0100 5620709 http://www.medworm.com/index.php?rid=5620708&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1q7665uvj2426251%2F The objective of this study was to reduce the recording duration of chemosensory event-related potentials (CSERP) and thereby to make the method more suitable for routine clinical use. Measurements were performed in the Department of Otorhinolaryngology of the university hospital of Cologne. Two protocols with different sequences [inter-stimulus intervals (ISI)-standard sequence: 30 s; PRS-15: pseudo-randomized sequence, mean ISI of 15 s] were applied to 40 volunteers to record CSERPs. To compare CSERP recordings under optimal and adverse test conditions, 20 younger/normosmic adults and 20 older/hyposmic participants were included in this study. Olfactory function was gauged using the “Sniffin’Sticks” test. For CSERP recordings, phenylethyl alcohol, hydrogen sulfide a... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5620708 Tue, 17 Jan 2012 07:18:53 +0100 5620708 http://www.medworm.com/index.php?rid=5620707&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1p3m777487778442%2F Abstract  Paranasal fungus ball can cause chronic rhinosinusitis. Removal via functional endoscopic sinus surgery is usually performed; however objective data on the overall benefit and patient satisfaction are very scarce. The study focuses on the clinical outcome and the quality of life following endoscopic surgery due to fungus ball sinusitis. Forty patients diagnosed with fungus ball sinusitis who underwent functional endoscopic surgery were included. Epidemiologic data, pre-, intra- and postoperative findings were recorded. Surgical success, the detailed benefit and the health-related quality of life were objectively assessed 1 year after the surgery based on a standardized questionnaire (modified SNOT 20) and the Glasgow Benefit Inventory. Health-related quality ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5620707 Tue, 17 Jan 2012 07:18:53 +0100 5620707 http://www.medworm.com/index.php?rid=5620711&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpk413w25j666m417%2F In this study, we emphasize the importance of an accurate and early diagnosis, followed by adequate surgical therapy and a multidisciplinary approach. Content Type Journal ArticleCategory OtologyPages 1-8DOI 10.1007/s00405-012-1924-8Authors E. Yorgancılar, Department of Otorhinolaryngology, Dicle University School of Medicine, Diyarbakir, 21280 TurkeyM. Yıldırım, Department of Otorhinolaryngology, Dicle University School of Medicine, Diyarbakir, 21280 TurkeyR. Gun, Department of Otorhinolaryngology, Dicle University School of Medicine, Diyarbakir, 21280 TurkeyS. Bakır, Department of Otorhinolaryngology, Dicle University School of Medicine, Diyarbakir, 21280 TurkeyR. Tekın, Department of Infectious Diseases, Dicle University School of Medicine, Diyarbakir, TurkeyC. Gocmez, Dep... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5620711 Tue, 17 Jan 2012 07:18:52 +0100 5620711 http://www.medworm.com/index.php?rid=5620710&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy2373w7041731n31%2F Abstract  Radiotherapy (RT) or concurrent chemoradiation therapy (CCRT) is not only effective at patients’ survival rates, but also produces undesirable late complications. The purpose of this study is to investigate the post-treatment late complications in nasopharyngeal carcinoma (NPC) patients, and to analyze the individual impact factors. We enrolled 188 newly diagnosed NPC patients who had received complete treatments and at least 3 years’ follow-up between March 1984 and March 2010. Late complications were modified from the Toxicity Criteria of the Radiation Therapy Oncology Group and the European Organization for Research and Treatment of Cancer. Of 188 patients, 132 were male and 56 were female. Eighty-eight patients received CCRT and the other 100 patients... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5620710 Tue, 17 Jan 2012 07:18:52 +0100 5620710 http://www.medworm.com/index.php?rid=5582949&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbt68336210510h82%2F The objective of the study is to present our multicentric experience on intraorbital lesions managed by means of an endonasal endoscopic approach. The study design used was multi-institutional retrospective review. We collected data on 16 intraorbital medially-located lesions, all managed by means of an endonasal route, treated in four different skull base centers. We retrospectively reviewed the technical details, complications, histology, and general outcome. The endoscopic endonasal approach was effective in removing completely intraorbital extra-intraconal tumors in 8 cases, in performing biopsies for histological diagnosis in 6 intraorbital intraconal tumors, and in draining 1 extraconal abscess. No major complications were observed; in particular, there was no optic nerve damag... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582949 Wed, 11 Jan 2012 17:52:57 +0100 5582949 http://www.medworm.com/index.php?rid=5582950&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3ng3185m62425303%2F Conclusions revealed that a 500 Hz STBs elicited consistently larger amplitudes, better reliability across recording sessions and fewer missing responses compared with click-induced VEMPs. Content Type Journal ArticleCategory MiscellaneousPages 1-7DOI 10.1007/s00405-011-1912-4Authors David Viciana, Otology & Neurotology Group CTS495, Department of Otolaryngology, Hospital de Poniente, Ctra de Almerimar s/n, El Ejido, 04700 Almería, SpainJose A. Lopez-Escamez, Otology & Neurotology Group CTS495, Department of Otolaryngology, Hospital de Poniente, Ctra de Almerimar s/n, El Ejido, 04700 Almería, Spain Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology) European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582950 Wed, 11 Jan 2012 17:52:56 +0100 5582950 http://www.medworm.com/index.php?rid=5582953&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr6042713rg698473%2F In conclusion, the SOT but only some subtest of the MCT could clearly distinguish between healthy adults and patient with acute unilateral vestibular loss. Equilibrium scores did not change significantly when the cervical spine was fixed with a collar. Acute fixation of the neck with a collar seems not to affect standing balance, even not when vestibular, visual and/or somatosensory input are also reduced. Content Type Journal ArticleCategory OtologyPages 1-7DOI 10.1007/s00405-011-1911-5Authors Silvia Bohne, Department of Otorhinolaryngology, University Hospital Jena, Lessingstrasse 2, 07740 Jena, GermanySabrina Heine, Department of Otorhinolaryngology, University Hospital Jena, Lessingstrasse 2, 07740 Jena, GermanyG. Fabian Volk, Department of Otorhinolaryngology, University Hos... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582953 Wed, 11 Jan 2012 17:52:54 +0100 5582953 http://www.medworm.com/index.php?rid=5582952&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh5j842748h7370r8%2F This study investigated if HP sinonasal colonization has a prognostic value for efficacy of functional endoscopic sinus surgery (FESS). Nasal polyps of 40 patients with CRS, undergoing FESS, were analyzed for presence of HP using immunohistochemistry (IHC). Patients were categorized as to whether the IHC was positive (HP+ group) or negative (HP− group). HP+ group and HP− group were compared according to the nasal polyp eosinophil density, and to the improvement (difference between pre- and post-operative scores) of the subjective symptom scores, and the nasal endoscopic scores. Nasal polyps in 28 (70%) patients were positive for HP. There were no significant differences between HP+ group and HP− group comparing the eosinophils, and the improvement of the single symptom and the tot... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582952 Wed, 11 Jan 2012 17:52:54 +0100 5582952 http://www.medworm.com/index.php?rid=5582951&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2gg0hj362l474408%2F The objective of the study was to compare the performance of cochlear implantation between post-meningitic and non-meningitic patients, and to evaluate the impact on hearing outcome of technical advances in cochlear implant technology. Retrospective chart review was used as the study design. Twenty adults with post-meningitic profound hearing loss receiving unilateral or bilateral cochlear implants between 1990 and 2008 were tested. Results were compared to a control group of 46 adults implanted for a non-meningitic hearing loss, with the same pre-operative speech scores. Speech scores were poorer in post-meningitic patients compared to those of control group, whatever the duration after implantation (p < 0.0001). Speech scores of subjects implanted and fitted before 2001... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582951 Wed, 11 Jan 2012 17:52:54 +0100 5582951 http://www.medworm.com/index.php?rid=5582954&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr8182124443243p7%2F This study shows that the NOSE and RhinoQoL questionnaires can be used in English- and French-speaking populations to perform pre- and post-therapeutic assessment. These validated instruments show that septoplasty without turbinectomy allows management of nasal obstruction and its burden. Content Type Journal ArticleCategory RhinologyPages 1-7DOI 10.1007/s00405-011-1916-0Authors Michel Mondina, Department of Otorhinolaryngology, Head and Neck surgery, University Hospital of Bordeaux, Centre F-X Michelet, Place Amélie Raba-Léon, 33076 Bordeaux, FranceMagali Marro, Department of Otorhinolaryngology, Head and Neck surgery, University Hospital of Bordeaux, Centre F-X Michelet, Place Amélie Raba-Léon, 33076 Bordeaux, FranceSylvie Maurice, Biostatistics Department, Université Victo... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582954 Mon, 09 Jan 2012 19:37:52 +0100 5582954 http://www.medworm.com/index.php?rid=5582956&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F83291727p72h7587%2F The objective of the study was the assessment of the long-term efficacy of submucosal uvulopalatopharyngoplasty in patients with obstructive sleep apnea syndrome. Thirty-two of 156 patients who underwent UPPP between January 2001 and March 2007 with a follow-up period of 36–96 months (mean, 56 months) were included in the study conducted at the university affiliated center. Preoperative and postoperative snoring evaluation forms and Epworth Sleepiness Scale (ESC) scores were used for subjective analysis. Preoperative and postoperative respiratory distress index (RDI) levels were evaluated objectively. Patients who had 50% or more reduction in RDI levels postoperatively were named as responders to the procedure. The other patients were named as non-responders. Body mass in... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582956 Mon, 09 Jan 2012 19:37:51 +0100 5582956 http://www.medworm.com/index.php?rid=5582955&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg81w32h302p1lj01%2F Abstract  The aim of this study is to clarify the prognostic value of the pathological overall tumor cellularity after neoadjuvant chemotherapy for locally advanced hypopharyngeal cancer. In consecutive series of 45 operable patients with locally advanced hypopharyngeal cancer, neoadjuvant chemotherapy by cisplatin and 5-fluorouracil was administered. Pathological image analysis was performed in 30 patients using the large cross-section specimen after total resection to evaluate the overall tumor cellularity. The chemotherapeutic responses were classified according to the pathological grading scale by dividing into four categories; more than 70% overall tumor cellularity in Grade 1, between an estimated 10 and 70% in Grade 2, less than 10% in Grade 3, and no identifiable ma... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582955 Mon, 09 Jan 2012 19:37:51 +0100 5582955 http://www.medworm.com/index.php?rid=5582957&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F07457w5227512371%2F Abstract  Palatal implants have been used to treat snoring and mild to moderate obstructive sleep apnea (OSA). Two previous controlled trials have published conflicting results regarding the effects of palatal implants on objective outcome measures, although they both could demonstrate superiority over placebo. The aim of the present study was to assess the effects of palatal implants in patients with mild to moderate sleep apnea in a randomised, placebo-controlled trial. Twenty-two patients with mild to moderate OSA (AHI 18 ± 5, BMI 28 ± 3, age 51 ± 13 years) due to palatal obstruction were enrolled in this randomised, double-blind, placebo-controlled trial. Respiratory parameters and sleep efficiency (evaluated by polysomnography), sno... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582957 Mon, 09 Jan 2012 06:33:01 +0100 5582957 http://www.medworm.com/index.php?rid=5582958&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F056044319u7q8563%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00405-011-1913-3Authors Petros V. Vlastarakos, ENT Department, Lister Hospital, Coreys Mill Lane, Stevenage, Hertfordshire SG1 4AB, UKBruno Kenway, ENT Department, Lister Hospital, Coreys Mill Lane, Stevenage, Hertfordshire SG1 4AB, UKGeorge Mochloulis, ENT Department, Lister Hospital, Coreys Mill Lane, Stevenage, Hertfordshire SG1 4AB, UK Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology) European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5582958 Sat, 07 Jan 2012 16:56:21 +0100 5582958 http://www.medworm.com/index.php?rid=5572638&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu02p7j7hq70352mq%2F Abstract  The purpose of this study is to determine if surgical approach to the inner ear is feasible without generating a hearing loss in an animal model. Five Macaca fascicularis were used as experimental animals and followed up for 27 months. Mastoidectomy, posterior tympanotomy and promontorial cochleostomy were performed on four specimens and one specimen was kept as control animal. Before and after drilling and exposing the endosteal layer and the membranous labyrinth, otoacustic emissions (dPOAE) and auditory brainstem responses (ABR) were used to test hearing. In vivo experimental studies prove it is reliable to expose the membranous labyrinth without causing hearing loss. dPOAE were present after 3, 6, 12, 24 and 26 months of follow-up. Regarding the ABR r... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5572638 Wed, 04 Jan 2012 17:02:41 +0100 5572638 http://www.medworm.com/index.php?rid=5572639&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj1520qnk63003r5m%2F Abstract  Hearing loss (HL) is the most common sensory impairment and is caused by a broad range of inherited to environmental causes. Inherited HL consists 50–60% of all HL cases. The inherited form of HL is further classified to different categories. More than 300 syndromes and 40 genes have been identified to result in different levels of HL. Although several diagnostic or screening tests have been developed, yet there are controversies around their use. Content Type Journal ArticleCategory Review ArticlePages 1-13DOI 10.1007/s00405-011-1910-6Authors Hossein Mahboubi, Department of Otolaryngology Head and Neck Surgery, University of California, Irvine, 101 The City Drive South, Bldg 56, Suite 500, Rt 81, Orange, CA 92868, USASami Dwabe, Department of Otolaryngology... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5572639 Wed, 04 Jan 2012 17:02:40 +0100 5572639 http://www.medworm.com/index.php?rid=5572640&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh573173v166159g2%2F Abstract  Treatment of oral and oropharyngeal cancer may cause dysphagia. Purpose is to examine whether cine magnetic resonance imaging (MRI) yields additional information compared to standard examination in the evaluation of posttreatment dysphagia and mobility of oral and oropharyngeal structures. Thirty-four cine MRIs were made in 23 patients with advanced oral and oropharyngeal cancer, consisting of an MR image every 800 ms during swallowing which is compared to videofluoroscopy and quality of life questionnaires. A scoring system was applied to assess mobility on cine MR and videofluoroscopy leading to a score ranging from 9 to 17. Cine MRI of the swallowing in a midsagittal plane visualized the tumor (if located in the same plane), important anatomic structures a... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5572640 Wed, 04 Jan 2012 17:02:36 +0100 5572640 http://www.medworm.com/index.php?rid=5572642&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg552028624701524%2F We describe a very unusual case of an inflammatory disorder of accessory parotid tissue in a 44-year-old male patient with concomitant, and previously unknown, aplasia of the main ipsilateral parotid gland. We also discuss the role of imaging and conservative therapeutic modalities such as botulinum toxin therapy and, in the future, minimally invasive endoscopic-assisted resection in the management of such salivary disorder. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00405-011-1902-6Authors Pasquale Capaccio, Dipartimento di Scienze Specialistiche e Chirurgiche, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Università degli Studi di Milano, Via F. Sforza 35, 20122 Milan, ItalyNicola Luca, Dipartimento di Scienze Specialistiche e Chirurg... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5572642 Wed, 04 Jan 2012 17:02:35 +0100 5572642 http://www.medworm.com/index.php?rid=5572641&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1707018250x04v66%2F Abstract  Quality of substitution voicing—i.e., phonation with a voice that is not generated by the vibration of two vocal folds—cannot be adequately evaluated with routinely used software for acoustic voice analysis that is aimed at ‘common’ dysphonias and nearly periodic voice signals. The AMPEX analysis program (Van Immerseel and Martens) has been shown previously to be able to detect periodicity in irregular signals with background noise, and to be suited for running speech. The validity of this analysis program is first tested using realistic synthesized voice signals with known levels of cycle-to-cycle perturbations and additive noise. Second, exhaustive acoustic analysis is performed of the voices of 116 patients surgically treated for advanced laryngeal canc... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5572641 Wed, 04 Jan 2012 17:02:35 +0100 5572641 http://www.medworm.com/index.php?rid=5572643&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg062069679452613%2F Abstract  A number of reports have investigated the relationship between laryngeal papilloma and human papilloma virus (HPV) infection. On the other hand, it is unclear whether the HPV infection is involved in the occurrence of pharyngeal papilloma. We hypothesized that HPV infection was involved in the occurrence of pharyngeal papilloma similarly to laryngeal papilloma. To verify this hypothesis, we investigated the presence of HPV infection. Furthermore, clinical manifestations of pharyngeal papilloma, which had rarely been reported, were discussed. A male-to-female ratio, solitary or multiple occurrences, and koilocytosis were examined in cases with pharyngeal papilloma. HPV DNA was examined with unfixed surgically resected specimens of pharyngeal papilloma. A screening ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5572643 Wed, 04 Jan 2012 06:59:58 +0100 5572643 http://www.medworm.com/index.php?rid=5560898&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1k13232ut6637252%2F Abstract  Auditory-evoked potentials represent the response of the auditory pathway to an auditory stimulus. Specific language impairment (SLI) children have delayed language development with difficulties in both understanding and producing spoken language. Hence, the purpose of this study was to determine whether a group of children with SLI had abnormal changes in the auditory middle latency response (AMLR). AMLR was obtained for 19 SLI children and they were studied and compared to normal. Audiological assessment and speech language tests were done for the study group. The results revealed no significant statistical differences between SLI children and the normal with regard to AMLR (P > 0.05). Our results suggest that children with SLI do not have abnormal a... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560898 Mon, 02 Jan 2012 16:46:36 +0100 5560898 http://www.medworm.com/index.php?rid=5560899&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8k76825934601352%2F Abstract  The aim of the study was to demonstrate the effects of nasal CPAP treatment on the morphology and function of nasal mucosa in patients with obstructive sleep apnea (OSA). Patients with complaints relevant to OSA underwent respiratory function tests, arterial blood gas analyses and polysomnography. Saccharine test and nasal biopsies were performed to assess the mucociliary transport time and to observe the histopathological changes in patients with apnea–hypopnea index ≥15 in whole night polysomnography. Tissue samples were obtained from middle and inferior turbinates and septal mucosa to observe the degree of inflammation and fibrosis by semiquantitative means. Biopsies and mucociliary transport test were performed before and 3 months after the initiation ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560899 Mon, 02 Jan 2012 16:46:35 +0100 5560899 http://www.medworm.com/index.php?rid=5560900&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq6h0365075688w5x%2F Abstract  The aim of the study was to investigate the validity of the avian middle ear model for researching the tympanoplasty mechanics. We studied the morphological details, acoustic transmission and quasi-static behavior of the ostrich tympano-ossicular system. The stained specimens of the ostrich middle ear were examined under a light microscope. The sound transfer function and quasi-static performance of the ostrich middle ear were evaluated using laser Doppler vibrometry. The application of pressure to the tip of the extracolumella causes a buckling movement of the ossicle between the cartilaginous and bony parts. Histologically, the intracolumellar connection can be identified as a junction zone between bone and hyaline cartilage. Sound conduction through the human m... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560900 Sat, 31 Dec 2011 06:37:14 +0100 5560900 http://www.medworm.com/index.php?rid=5560902&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd051186058088m7j%2F Abstract  Spasmodic dysphonia voices form, in the same way as substitution voices, a particular category of dysphonia that seems not suited for a standardized basic multidimensional assessment protocol, like the one proposed by the European Laryngological Society. Thirty-three exhaustive analyses were performed on voices of 19 patients diagnosed with adductor spasmodic dysphonia (SD), before and after treatment with Botulinum toxin. The speech material consisted of 40 short sentences phonetically selected for constant voicing. Seven perceptual parameters (traditional and dedicated) were blindly rated by a panel of experienced clinicians. Nine acoustic measures (mainly based on voicing evidence and periodicity) were achieved by a special analysis program suited for strongly ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560902 Fri, 30 Dec 2011 16:42:03 +0100 5560902 http://www.medworm.com/index.php?rid=5560901&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw88815w6jp088t06%2F Abstract  Our aim is to evaluate the function and take rate of 0.2 mm thickness cartilage shield for repair of subtotal tympanic membrane perforation by comparing it with full thickness cartilage and temporalis fascia. Repair of tympanic membrane was done in 85 patients with unilateral chronic otitis media with subtotal perforation. The patients were classified into three groups: group ‘A’ where 0.2 mm thickness cartilage graft was used, group ‘B’ repaired with full thickness cartilage graft and group ‘C’ where temporalis fascia graft was used. Over the follow-up period, we found that the graft take was complete with both partial and complete thickness cartilage grafts while it was not complete in fascia cases. On the other hand, there was marked improv... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560901 Fri, 30 Dec 2011 16:42:03 +0100 5560901 http://www.medworm.com/index.php?rid=5560903&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2l26j16k41686333%2F Abstract  The aim of this study was to evaluate the demographic and clinicopathologic characteristics of gastroesophageal reflux disease (GERD) with and without laryngopharyngeal reflux (LPR) to determine the risk factors for the occurrence of LPR in patients with GERD. This is a retrospective study of GERD patients with and without LPR. From the outpatient computer program of our hospital we randomly enrolled 45 GERD patients with LPR into the first group and another 45 GERD patients without LPR to the second group. Medical records of the patients in both groups were examined. All patients underwent upper gastrointestinal system endoscopy. LPR was confirmed by laryngoscopy, and LPR-related laryngoscopy scoring. Non-erosive GERD (NERD), erosive GERD (ERD) and Barrett’s es... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560903 Fri, 30 Dec 2011 07:10:04 +0100 5560903 http://www.medworm.com/index.php?rid=5560904&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhl5574521673g76m%2F Abstract  The correlation between p16 upregulation and high-risk HPV infection is well known in head and neck squamous cell cancer. However, no information is available on rare carcinomas of the minor salivary glands. We analyzed 38 samples of minor salivary gland malignancies. p16 expression was determined by immunohistochemistry, HPV DNA by using in situ hybridization to detect low (type 6 and 11) and high (type 16 and 18) risk HPV types. In 71% of samples p16 expression was found. Low-risk HPV DNA could not be detected in any of the samples, whereas high-risk HPV DNA was found in two samples of mucoepidermoid carcinoma, which also showed the highest immunoreactivity with p16. HPV infection does not seem to be a common event in minor salivary gland carcinoma. Upregulation... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560904 Fri, 30 Dec 2011 07:10:03 +0100 5560904 http://www.medworm.com/index.php?rid=5560905&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1446027641727772%2F Content Type Journal ArticleCategory ObituaryPages 1-2DOI 10.1007/s00405-011-1879-1Authors Rainer Weber, Department of Otolaryngology, Head and Neck Surgery, Rhinology Center Marburg, UKGM, Baldinger Straße, 35043 Marburg, GermanyJan Olofsson, Department of Otolaryngology, Head and Neck Surgery, Haukeland University Hospital, 5021 Bergen, NorwayJochen A. Werner, Department of Otolaryngology, Head and Neck Surgery, Philipp University of Marburg, Baldinger Str., 35043 Marburg, Germany Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology) European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560905 Fri, 30 Dec 2011 07:10:02 +0100 5560905 http://www.medworm.com/index.php?rid=5560906&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgll795173464371x%2F Abstract  The aim of this study was to evaluate the value of FNA, Tb-PCR, and CBC as an initial work-up protocol for cervical lymphadenopathy to reiterate the importance of CBC in terms of predicting the clinical course. In this consecutive case series, 158 patients with cervical lymphadenopathy were enrolled. All patients underwent FNA and CBC, with or without Tb-PCR. The validity of combined FNA ± Tb-PCR and CBC in the diagnosis of diseases requiring definitive treatment was evaluated. Final diagnoses were self-limiting disease in 110 (69.6%), malignancy in 19 (12.0%), and tuberculosis in 26 (16.5%). Sensitivity of FNA ± Tb-PCR was 66.7% and of added CBC profile was 97.9%. Patients with neutropenia or lymphocytosis were found to have a higher chance o... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560906 Fri, 30 Dec 2011 07:10:01 +0100 5560906 http://www.medworm.com/index.php?rid=5560908&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpkq2306525516851%2F In conclusion, this study demonstrates the easy handling of FS application in tonsillectomy. Its use instead of EC after cold-steel tonsillectomy shows beneficial effects on mucosal recovery, as assessed by a decrease in the thickness of wound coating. Furthermore, FS is associated with a significantly shortened duration of pain-medication use and overall reduction in consumption/demand. Content Type Journal ArticleCategory Head and NeckPages 1-8DOI 10.1007/s00405-011-1904-4Authors Christian Mozet, Department of Otolaryngology, Head and Neck Surgery, University of Leipzig, Liebigstrasse 10-14, 04103 Leipzig, GermanyChristiane Prettin, Clinical Trial Centre Leipzig-CTC Leipzig, University of Leipzig, Leipzig, GermanyMaria Dietze, Department of Otolaryngology, Head and Neck Surgery... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560908 Fri, 30 Dec 2011 07:10:00 +0100 5560908 http://www.medworm.com/index.php?rid=5560907&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy616172580771382%2F In conclusion, management of allergic rhinitis is very important in treating OSA patients in order to eliminate stress and fatigue and to minimize daytime sleepiness and quality of life. Content Type Journal ArticleCategory RhinologyPages 1-4DOI 10.1007/s00405-011-1888-0Authors Cheol Eon Park, Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-702 KoreaSeung Youp Shin, Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-702 KoreaKun Hee Lee, Department of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, 1 Hoegi-dong, Dongdaemun-gu, Seoul, 130-702 KoreaJoong Saeng Cho, Depart... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560907 Fri, 30 Dec 2011 07:10:00 +0100 5560907 http://www.medworm.com/index.php?rid=5560909&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx7235q1550761868%2F Abstract  Hearing loss from otitis media (OM) can affect young children’s development. Some children with persistent OM-related hearing loss and associated problems can benefit from treatment, but researchers and clinicians are still unclear on how to identify them best. The present study aims to determine which factors are most related to the hearing loss in OM, as a first step towards an effective case-finding instrument for detecting infants with persistent OM-related hearing loss. The full PEPPER (‘Persistent Ear Problems, Providing Evidence for Referral’) item pool includes a wide range of risk factors for OM in a single questionnaire, and is easily completed by parents or guardians. The questionnaire was sent to all children invited for the universal hearing scr... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5560909 Fri, 30 Dec 2011 07:09:59 +0100 5560909 http://www.medworm.com/index.php?rid=5552827&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc748263293756655%2F Abstract  Considerable sound levels are produced in primary schools by voices of children and resonance effects. As a consequence, hearing loss and mental impairment may occur. In a Cologne primary school, sound levels were measured in three different classrooms, each with 24 children, 8–10 years old, and one teacher. Sound dosimeters were positioned in the room and near the teacher’s ear. Additional measurements were done in one classroom fully equipped with sound-absorbing materials. A questionnaire containing 12 questions about noise at school was distributed to 100 children, 8–10 years old. Measurements were repeated after children had been taught about noise damage and while “noise lights” were used. Mean sound levels of 5-h per day measuring period ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5552827 Wed, 28 Dec 2011 16:45:30 +0100 5552827 http://www.medworm.com/index.php?rid=5552829&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0532up7426872363%2F The objective of the study is to compare the pain level of three methods of intratympanic (IT) injections using prospective, randomized clinical study in a tertiary care center. 39 patients with Ménière’s disease and 30 patients with sudden sensorineural hearing loss are included. Excluded were patients treated for a chronic pain or those who took any pain killer for the last 24 h. Each patient received one IT injection a week, for three consecutive weeks. Three methods of IT injections were compared, with the application of EMLA cream on the tympanic membrane filling the external auditory canal 60 min before the procedure, with subcutaneous injection of lidocaine 1% with 1:100,000 epinephrine in the external auditory canal, and finally with an IT injection without any ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5552829 Tue, 27 Dec 2011 16:50:42 +0100 5552829 http://www.medworm.com/index.php?rid=5552828&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg057815730705t53%2F This study showed that the high concentrations of singulair also had an anti-cholinergic effect for relieving symptoms of asthma. Content Type Journal ArticleCategory RhinologyPages 1-5DOI 10.1007/s00405-011-1880-8Authors Li-Hsiang Cheng, Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-Gong Road, Neihu District, Taipei, TaiwanChuan-Hsiang Kao, Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-Gong Road, Neihu District, Taipei, TaiwanChih-Hung Wang, Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-Gong Road, Neihu Distri... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5552828 Tue, 27 Dec 2011 16:50:42 +0100 5552828 http://www.medworm.com/index.php?rid=5552830&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp0725201120m934q%2F In conclusion, lowered HRQoL, low mood, a high T stage, high alcohol consumption, high neuroticism, coping by avoidance and coping by problem solving directly predicted worse distress as measured by high GHQ scores, whereas neuroticism was also associated with GHQ through choice of coping. Content Type Journal ArticleCategory Head and NeckPages 1-8DOI 10.1007/s00405-011-1884-4Authors Anne K. H. Aarstad, Department of Surgical Sciences, Faculty of Medicine, University of Bergen, 5021 Bergen, NorwayElisabeth Beisland, Department of Otolaryngology/Head and Neck Surgery, Haukeland University Hospital, 5021 Bergen, NorwayHans J. Aarstad, Department of Surgical Sciences, Faculty of Medicine, University of Bergen, 5021 Bergen, Norway Journal European Archives of Oto-Rhino-Laryngol... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5552830 Mon, 26 Dec 2011 16:44:09 +0100 5552830 http://www.medworm.com/index.php?rid=5544918&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2r44647pl4x32810%2F In this study, β-catenin cellular location and E-cadherin expression levels were analyzed in 16 laryngeal squamous cell carcinomas (LSCCs) (9 glottic and 7 supraglottic) and 11 samples of non-tumoral inflammatory larynx tissue, using immunohistochemical methods. All non-tumoral tissues showed equally strong membranous expression of β-catenin, while cytoplasmic expression was found in only 3 of the 11 samples. By contrast, whereas 8/9 glottic LSCCs exhibited only membranous expression of β-catenin, 6/7 supraglottic LSCCs displayed both membranous and cytoplasmic expression (p = 0.003). Strong E-cadherin staining was observed in 9/11 non-tumoral tissues and 7/9 glottic LSCCs, whereas 4/7 supraglottic LSCCs exhibited weak expression. Reduced membrane expression of E-cadheri... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5544918 Sat, 24 Dec 2011 16:44:59 +0100 5544918 http://www.medworm.com/index.php?rid=5544919&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh54m36tw01828796%2F We report a case of tonsil amyloidosis and review the characteristics of this exceptional pathology. A 74-year-old man consulted for odynophagia, upper dysphagia and deteriorated general health status, which have been evolving for 1 year. Clinical examination found a smooth swelling of the right palatine tonsil. No further abnormalities were noted. The biopsy findings were consistent with amyloidosis. Etiological assessment pointed to Waldenstrom macroglobulinemia. Tonsillectomy was performed. The patient was managed by chemotherapy associating chlorambucil, vincristine and prednisone. The progress after chemotherapy was good. Localized amyloidosis is a rare lesion of the superior aerodigestive tract, predominating in the larynx and tonsil involvement is exceptional. Its diagnos... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5544919 Sat, 24 Dec 2011 16:44:58 +0100 5544919 http://www.medworm.com/index.php?rid=5544920&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl6n53w05705x5822%2F In this study, 24 healthy Sprague-Dawley type rats of age 3–4 months and 250–300 g weight were used. Rats have been divided into three random groups. Topical ciprofloxacin was administered to the rats in the first group and topical prednisolone was administered to the rats in the third group; no medication was applied to their opposite ears and they were determined as control group. Prednisolone was administered to one ear of the rats and ciprofloxacin was administered to their opposite sides in the second group. After bilateral myringotomies the treatments were applied for 20 days as five drops two times a day. Otomicroscopic examination was made on the 10th day and reperforations were made when necessary. Rats were killed on the 21st day and temporal bone dissect... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5544920 Sat, 24 Dec 2011 06:41:46 +0100 5544920 http://www.medworm.com/index.php?rid=5544921&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx38t017806251m75%2F This study evaluated the myocutaneous platysma flap (MPF) as an alternative to free flaps for closing defects after head and neck tumor resection in selected cases. MPFs were used to close small to medium-sized full-thickness oral and pharyngeal defects after surgery for tumors staged cT1-3 (oral cavity 37.1%, oropharynx 24.3%, hypopharynx 38.6%) in 70 patients. Flap-related complications developed in 27% of cases (partial necrosis 7%, total necrosis 3%, salivary fistula 11.4%, bleeding/hematoma 5.7%) and donor-site complications in 10%. Defect closure was adequate in 97%; 62.5% of the patients required intraoperative tracheotomies (closed again in 72.5%). Postoperative swallowing was not significantly disturbed in 72% of the patients. The MPF allows closure of small to medium-sized ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5544921 Fri, 23 Dec 2011 16:53:00 +0100 5544921 http://www.medworm.com/index.php?rid=5544922&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1742ng3815746478%2F Abstract  Tinnitus has been defined as a phantom auditory perception. Research indicates the necessity to make a distinction between the physical symptom and the subjective severity of the tinnitus symptom, since especially the latter seems to vary among patients. The relationship between tinnitus severity and psychological variables has been well established. Anxiety is considered to be an important variable for understanding the differences in the subjective tinnitus severity. Although many studies confirm the relationship between anxiety and tinnitus severity, most studies do not take the possibility of shared method variance and content overlap between questionnaires into account. Furthermore, anxiety is a broad concept and contains both a cognitive and somatic dimensio... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5544922 Thu, 22 Dec 2011 16:38:04 +0100 5544922 http://www.medworm.com/index.php?rid=5544923&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg6t87q2k1022278k%2F Abstract  To evaluate the role of oVEMP and multidetector CT scan in patients with superior canal dehiscence syndrome. Prospective study was conducted on nine patients with superior canal dehiscence syndrome (5 females, 4 males) age ranged 19–49 with mean age of 32.7 ± 9.3 years, complaining of intolerance to loud sounds and/or oscillopsia. The mean duration of illness was 18.7 ± 6.9 months, nine normal individuals as control (age and gender matched) were also included in the study. All of them underwent oVEMP and MDCT scan. Patients were of bilateral normal hearing sensitivity with no conductive impairment. All of the studied subjects (patients and controls) had identifiable contralateral oVEMP responses. MDCT scan showed dehiscence in all ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5544923 Thu, 22 Dec 2011 12:51:09 +0100 5544923 http://www.medworm.com/index.php?rid=5544924&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F70818r1248322380%2F Abstract  Music perception is considered unsatisfactory for most cochlear implant (CI) users. Usually, rhythm identification is adequate while pitch and melody recognition are rather limited. The aim of this study was to investigate whether insufficient contour information in the low-frequency range is one cause that contributes to the poor melody recognition results in CI users. For this purpose, the recognition of familiar melodies was tested with three differently expanded pitch contours. Ten cochlear implant subjects and five normal-hearing (NH) volunteers were investigated. Each subject chose ten out of a possible set of 23 well-known nursery songs without verbal cues. The songs were played in the original version and with three different pitch-contour expansions. All ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5544924 Thu, 22 Dec 2011 12:51:08 +0100 5544924 http://www.medworm.com/index.php?rid=5538479&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe3l6446771h27522%2F This study aimed at investigating the survival rate and prognostic factors of laryngeal carcinoma patients in the absence of the use of laryngectomy, radiotherapy, and chemotherapy. A total of 167 cases of laryngeal carcinoma without the use of laryngectomy, radiotherapy, or chemotherapy were analyzed retrospectively. Surveyed items included age, smoking history, tumor family history, tuberculosis history, primary site, pathological grade, T-stage, N-stage, clinical stage, and whether tracheotomy had been performed. Survival rates were calculated using the Kaplan–Meier method. For univariate analysis, comparison among/between groups was performed using the log-rank test. Multivariate analysis was carried out using the Cox proportional hazard model. Overall median survival time was ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5538479 Tue, 20 Dec 2011 16:44:27 +0100 5538479 http://www.medworm.com/index.php?rid=5538480&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6175517g01510n03%2F Abstract  One of the most important adverse effects of cisplatin, a chemotherapeutic agent which is widely used in the treatment of cancer patients, is hearing loss. This has primarily been associated with the loss of inner ear hairy and spiral ganglion cells due to oxidative stress. Resveratrol is known to be an antioxidant agent, which has the theoretical potential of preventing cisplatin-related ototoxicity. This experimental study was approved by Animal Ethics Committee of Inonu University (2008–20) and supported by Inonu University Scientific Research Projects Support Fund (2009–17). Thirty-four 3-month-old Wistar albino female rats weighing 210–270 g were used in the study. The animals were allocated into four groups: in cisplatin group (Group A), a single ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5538480 Tue, 20 Dec 2011 16:44:26 +0100 5538480 http://www.medworm.com/index.php?rid=5538481&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv40255x6k3w24u61%2F Content Type Journal ArticleCategory Book ReviewPages 1-1DOI 10.1007/s00405-011-1797-2Authors Per Møller, Department of Otolaryngology/Head and Neck Surgery, Haukeland University Hospital, Bergen, Norway Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology) European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5538481 Tue, 20 Dec 2011 16:44:24 +0100 5538481 http://www.medworm.com/index.php?rid=5538482&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft5m02820806x5070%2F Abstract  Epistaxis and alcohol overconsumption are frequently encountered in patients admitted to emergency wards. The aim of the study was to analyze indirect markers of alcohol overconsumption in epistaxis patients and evaluate its role as a risk factor. In a cohort of 510 epistaxis patients indirect markers of alcohol overuse were measured including the mean corpuscular volume (MCV), gamma glutamyltransferase (GGT), aspartate aminotransferase and alanine aminotransferase. The results were compared to the normal findings in literature. Pathologic mean levels of GGT were found in epistaxis patients. Almost 5% had macrocytosis and MCV correlated positively with liver enzyme levels. Platelet counts were negatively correlated with both corpuscular volumes and liver enzymes. ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5538482 Tue, 20 Dec 2011 06:43:17 +0100 5538482 http://www.medworm.com/index.php?rid=5525662&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F13pn1572334730j1%2F The objectives of this article are to assess the frequency and significance of facial paralysis and undiagnosed nerve infiltration in patients with parotid malignancies. 103 patients with parotid gland malignancies were treated in a single institution, the tertiary center for ENT at the University Department in Poznan between 1996 and 2006. Facial palsy at the initial presentation was found in 32 patients. The stage of the primary tumor in the examined group of 103 patients is as follows: 20—T1, 31—T2, 20—T3, 32—T4. The correlation between facial nerve function before treatment and patients’ characteristics, including the treatment methods, were analyzed. Intact facial nerve function at patient presentation was a very strong prognostic factor determining the treatment and f... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5525662 Sat, 17 Dec 2011 16:43:38 +0100 5525662 http://www.medworm.com/index.php?rid=5515863&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7723461316523619%2F Content Type Journal ArticleCategory AbstractsPages 1-5DOI 10.1007/s00405-011-1852-z Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology) European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5515863 Tue, 13 Dec 2011 17:05:44 +0100 5515863 http://www.medworm.com/index.php?rid=5515862&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff32rg24x07813625%2F Abstract  The aim of this study was to find out whether objective analysis of snoring sounds (sound pressure level and psychoacoustic parameters) correlates with the subjective rating by participants with respect to perceived annoyance and hence whether it is useful. 43 participants, aged 22–65 years with normal hearing, were asked to rate 60 snoring sounds from simple and obstructive snorers according to their level of annoyance. A correlation analysis according to Spearman was then performed on objectively calculated parameters. These were the A-weighted sound pressure level, the psychoacoustic parameters of loudness, sharpness, fluctuation strength and roughness and psychoacoustic annoyance (PA) calculated from those parameters. The subjective ratings showed high,... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5515862 Tue, 13 Dec 2011 17:05:44 +0100 5515862 http://www.medworm.com/index.php?rid=5505832&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5448265644248xx7%2F Abstract  This is a double bind clinical trial which evaluated harmonic scalpel versus bipolar diathermy tonsillectomy The study was conducted at Diyarbakir government hospital, Diyarbakir, Turkey. The study population comprised 144 patients, aged 4–18 years (mean 9 years  ± 4.12 SD). All patients underwent tonsillectomy with or without adenoidectomy. The indications for tonsillectomy were obstructive sleep apnea (84 patients [58.3%]) and chronic tonsillitis (60 patients [41.7%]). All 144 patients were randomly divided into two groups: bipolar dissection (81 patients [56.2%] with mean age 8.98 years ± 4.22) and harmonic scalpel (63 patients [43.8%] with mean age 9 years ± 4.02). BD group showed statistically signifi... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5505832 Mon, 12 Dec 2011 17:13:18 +0100 5505832 http://www.medworm.com/index.php?rid=5505833&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk457450u38425157%2F We report our results on a prospective, randomized controlled trial involving 50 patients with chronic bilateral rhino sinusitis. We eliminated various confounding factors by studying a single group of patients, with symmetrical disease, without pre-existing gross anatomical abnormalities. Patients requiring revision sinus surgery were excluded. On completion of the surgery, a cotton pledget soaked in Mitomycin C was placed in one nostril (test) and saline-soaked pledget (control) was placed in the other side of the nose, both in the middle meatus. The side of the nasal cavity receiving the topical Mitomycin C was randomized. The patients were assessed periodically (first week, first month, third month and sixth month) for synechiae formation and presence or absence of their symptoms... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5505833 Mon, 12 Dec 2011 17:13:16 +0100 5505833 http://www.medworm.com/index.php?rid=5505834&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj1875g44761q58x8%2F Abstract  Brain and immune system are linked by bidirectional pathways so that changes of the central nervous system may influence various immune functions. The olfactory system may be involved in this interaction. In most odor studies subjects are aware of an odor exposure, using frequently high odor concentrations or long-term exposures without controls. In this pilot study, the potential immune effects of short-term odor exposure were examined in 32 blinded subjects (16 male, 16 female). Subjects were exposed without their knowledge either to a stimulant essential oil (grapefruit, fennel, pepper), a no-odor control or a relaxant essential oil (lavender, patchouli, rose) during a set of psychological questionnaires for 30 min at three separate visits. Activity of neu... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5505834 Mon, 12 Dec 2011 17:13:15 +0100 5505834 http://www.medworm.com/index.php?rid=5505835&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa72j5h313v118294%2F Abstract  The skin adhesive Histoacryl® consists of n-butyl-2-cyanoacrylate which polymerises in contact with moisture. It is not fully biodegradable, produces heat during polymerisation and releases products which are toxic and inhibit cell growth. Clinical application is exclusively approved to glue skin. However, there are also clinical studies and case reports in the scientific literature, which discuss the application of Histoacryl® as a soft tissue adhesive. In parallel to an analysis of the literature which discusses the usage of Histoacryl® in head and neck surgery, we performed in vitro and in vivo investigations with this adhesive. In vitro, the vitality of cultured cell lines which where treated with extracts of Histoacryl® was determined with a viability assay... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5505835 Mon, 12 Dec 2011 17:13:14 +0100 5505835 http://www.medworm.com/index.php?rid=5495231&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F72q8281270665hm3%2F Abstract  Waardenburg syndrome (WS) is an autosomal dominant disease, characterized by dystopia canthorum, hyperplasia of the eyebrows, heterochromia iridis, white forelock, and congenital sensori-neural hearing loss (SNHL). The aim of this study was to evaluate the outcome of cochlear implantation in children with WS and compare it with children with pure SNHL. In a prospective study we evaluated 336 cochlear implanted children from 2008 to 2010. The WS was diagnosed by its established criteria and for control group children without any dysmorphic features, anatomical, behavioral, and developmental disorders were also enrolled. We evaluated children of both groups 1 year after cochlear implantation by categories of auditory performance (CAP) and speech intelligibility... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5495231 Sat, 10 Dec 2011 16:55:19 +0100 5495231 http://www.medworm.com/index.php?rid=5495230&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff023944h40j268km%2F Abstract  It is hypothesized that real time objective measurement of the subglottic pressure could contribute to the choice of the implant’s size (IS) in medialization thyroplasty (MT). A prospective study was conducted with patients with glottal insufficiency. Patients had a MT using a Montgomery implant® (Boston medical, Boston, USA). Peak direct subglottic pressure (PDSGP) was measured intraoperatively using a catheter inserted in the cricothyroid membrane. The implant’s choice was based on the results of PDSGP measured prior and after placement of the implant and was compared to the surgeon’s and patient’s perception and fiber optic estimation of the glottis aperture. Six patients were included in the first part of the study. The PDSGP could be measured in all t... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5495230 Sat, 10 Dec 2011 16:55:19 +0100 5495230 http://www.medworm.com/index.php?rid=5495232&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw0u4236xu334647r%2F Abstract  Paranasal sinus anatomical anomalies with unknown etiology are common. Maxillary and/or frontal sinus aplasia or hypoplasia are more common than the other types. Although there are some reports about paranasal sinus anomalies in the literature, there is no case similar to ours, with total paranasal sinus aplasia. Here, we present a unique case of total paranasal sinus aplasia with a symptom of fullness on the face. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00405-011-1871-9Authors Saban Celebi, Otorhinolaryngology Department, Haseki Education and Research Hospital, Istanbul, TurkeyUmit Taskin, Otorhinolaryngology Department, Bagcilar Education and Research Hospital, Nafiz Gürman Cad. No 1.Fatih, Istanbul, TurkeyFazilet Altın, Otorh... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5495232 Fri, 09 Dec 2011 17:09:02 +0100 5495232 http://www.medworm.com/index.php?rid=5495233&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh532135p54612537%2F Content Type Journal ArticleCategory Acknowledgement to refereesPages 1-3DOI 10.1007/s00405-011-1828-z Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology) European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5495233 Fri, 09 Dec 2011 06:50:18 +0100 5495233 http://www.medworm.com/index.php?rid=5495235&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq063660h72678202%2F Abstract  Eustachian tube (ET) primary tumors and tumor-like lesions are rare diseases presenting with common ear, nose and throat symptoms. Pathology can range from developmental anomalies to high malignant neoplasms. Hence this review aimed at suggesting a classification and outline relevant aspects of ET primary tumors and tumor-like lesions, describing clinical findings, diagnostic management and therapeutic approaches. MEDLINE, CINAHL, OVIDSP, HIGHWIRE, and GOOGLE databases were searched from inception to July 2011 for relevant studies. Further papers were identified by examining the reference lists of all included. Sixty-five papers met the inclusion criteria, enclosing 78 cases. Case reports are increasing in the past few years. Benign lesions and tumor-like lesions ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5495235 Thu, 08 Dec 2011 18:24:27 +0100 5495235 http://www.medworm.com/index.php?rid=5495234&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F16wp01757m168r76%2F Abstract  The aim of this study was to investigate the effects of four different types of nasal packs on pain, nasal fullness and postoperative bleeding following septoplasty. Prospective randomised double blind study was conducted. The study group included 119 patients who underwent endonasal septoplasty under general anaesthesia. Four types of nasal packing materials were utilized: (1) Merocel standard 8-cm nasal dressing without airway, (2) Doyle Combo splint (DCS), (3) Merocel in a glove finger and (4) Vaseline gauze. All packs were removed at the 48th hour (±3 h) after the surgery. Three different variables were investigated following the surgical procedure: (1) pain, (2) nasal fullness and (3) bleeding after removal of the nasal packing material. DCS produced th... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5495234 Thu, 08 Dec 2011 18:24:27 +0100 5495234 http://www.medworm.com/index.php?rid=5487690&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbh7409u1j432v235%2F Abstract  To investigate the cytotoxic effects of nasal buserelin on rabbit nasal mucosal tissue, twenty-four female rabbits were studied prospectively. The rabbits were divided into 4 groups including 6 rabbits. The rabbits’ left noses were included in the all study groups: 150 μg/puff/day of buserelin acetate was administered topically twice daily during 21, 42 and 63 days. Saline was administered topically twice daily to the left nasal cavity in the control group. The nasal septal mucosal stripe tissue was carefully removed from underlaying cartilage after sedation. HE staining, Masson’s trichrome, toluidine blue and TUNEL staining were used to evaluate mucosal changes. Each preparation was investigated via apoptotic cells, and they were accounted. Kruskal�... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487690 Wed, 07 Dec 2011 12:54:47 +0100 5487690 http://www.medworm.com/index.php?rid=5487689&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkmm4014440wt4773%2F The objective of the study was to determine the therapeutic efficacy of early combined treatment with intratympanic steroid injection (ITSI) in patients with severe to profound sudden sensorineural hearing loss (SSNHL), who did not respond to initial systemic steroid treatment (SST). The study design included historical controlled trials (retrospective analysis for the SST group). Patients (n = 73; 38 women and 35 men) diagnosed with severe to profound SSNHL at the time of their first visit in tertiary referral centers were recruited. Among these 73 patients, 30 patients who showed no early response within a week after the start of initial SST were prospectively included as the ITSI group. ITSI was performed twice a week for two consecutive weeks. In contrast, 43 patients w... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487689 Wed, 07 Dec 2011 12:54:47 +0100 5487689 http://www.medworm.com/index.php?rid=5487691&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa722636n6010r6n7%2F We report our experience with island cartilage tympanoplasty in revision cases and assess the anatomical and functional outcomes. We conducted a retrospective chart review at a tertiary referral center for patients who underwent revision tympanoplasty using cartilage with the island technique without mastoidectomy between January 2002 and December 2008. 60 cases were included in the study and successful closure without reperforation was obtained in 52 of 60 patients (87%). Three failed cases underwent a subsequent procedure endaurally with a positive result (92% accumulated success rate). Average postoperative pure-tone audiometry air-bone gap was 13 ± 7 dB compared with 21 ± 11 dB preoperatively (p = 0.004). An overall postoperative air-bone ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487691 Tue, 06 Dec 2011 17:01:06 +0100 5487691 http://www.medworm.com/index.php?rid=5487694&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq7v886748262318q%2F In conclusion, the SSIACRT regimen with a lower dose of CDDP (100 mg/body) had an equivalent therapeutic outcome and lower toxic outcome compared to a higher dose of CDDP. This regimen could be an effective and safe therapeutic modality for maxillary squamous cell carcinoma except T4b and N1/2 disease. Content Type Journal ArticleCategory Head and NeckPages 1-7DOI 10.1007/s00405-011-1857-7Authors Yuji Kanazawa, Department of Otolaryngology, University of Toyama, 2630 Sugitani, Toyama, 930-0194 JapanHideo Shojaku, Department of Otolaryngology, University of Toyama, 2630 Sugitani, Toyama, 930-0194 JapanHiromasa Takakura, Department of Otolaryngology, University of Toyama, 2630 Sugitani, Toyama, 930-0194 JapanMichiro Fujisaka, Department of Otolaryngology, University of Toyama, ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487694 Tue, 06 Dec 2011 17:01:04 +0100 5487694 http://www.medworm.com/index.php?rid=5487693&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9072243296823507%2F This study demonstrates that ECD is an effective and safe treatment for selected benign PPS tumors. It has a favorable clinical outcome and an acceptable aesthetic result, and can be performed in a minimally invasive fashion. Therefore, it is suggested that ECD be included in the treatment modalities of benign PPS tumors. Content Type Journal ArticleCategory Head and NeckPages 1-6DOI 10.1007/s00405-011-1855-9Authors Tsung-Lin Yang, Department of Otolaryngology, National Taiwan University Hospital, National Taiwan University College of Medicine, 7, Chung-Shan South Rd, Taipei, TaiwanTzu-Yu Hsiao, Department of Otolaryngology, National Taiwan University Hospital, National Taiwan University College of Medicine, 7, Chung-Shan South Rd, Taipei, TaiwanCheng-Ping Wang, Department of Otol... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487693 Tue, 06 Dec 2011 17:01:04 +0100 5487693 http://www.medworm.com/index.php?rid=5487692&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh1g468x1kx7870r1%2F In this study, we determined nucleotides polymorphisms in the Cp and Qp promoter regions in peripheral blood mononuclear cells (PBMCs) from Cantonese healthy carriers and in biopsies of NPC, nasal NK/T lymphoma, BL, and gastric carcinoma. The sequence changes of −12G>T and +69 C>T in Cp and −197 G>A and +1 G>C in Qp were frequently identified in NPC. Transient transfection studies using luciferase gene reporters revealed a significant reduction (57.11%) in gene expression from the Cp +69T variant and increased expression (43.5%) from the Qp +1C variant compared to the prototype, suggesting that these sequence variations affect promoter activity. Our results indicate that the nucleotides polymorphisms in Cp and Qp occur frequently in NPC and might contribute to the onc... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487692 Tue, 06 Dec 2011 17:01:04 +0100 5487692 http://www.medworm.com/index.php?rid=5487695&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg38x467527537q26%2F The objective of this study was prospectively to assess the feasibility and safety of transoral robotic surgery (TORS) in head and neck carcinomas and to report our learning curve and 2-year outcomes. Patients with oropharyngeal, hypopharyngeal and laryngeal tumors treated with TORS were prospectively included. We evaluated: the feasibility of TORS, robotic set-up time, transoral robotic surgery time, blood loss, surgical margins, tracheotomy, feeding tube, time to oral feeding and surgery-related complications. Twenty-three patients were treated for 25 carcinomas. Twenty-two patients underwent successful robotic resection for 24 carcinomas (96%). One patient required conversion to open surgery due to massive bleeding. The mean robotic set-up time was 25 min (range: 15–100&nbs... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487695 Mon, 05 Dec 2011 17:33:58 +0100 5487695 http://www.medworm.com/index.php?rid=5487696&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0q54874816780g75%2F Abstract  Patients with profound sudden sensorineural hearing loss (SSNHL) have a poor prognosis regardless of the type of treatment they receive. However, there is evidence that a proportion of patients with profound hearing loss may exhibit variable degrees of recovery, and this has yet to be specifically investigated. Here, we report a comparison of levels of hearing improvement in patients stratified according to their level of hearing threshold before treatment. We divided patients with severe to profound SSNHL into three groups: patients with an initial hearing threshold of 80–89 dB (n = 18), 90–99 dB (n = 16), and ≥100 dB (n = 34). We compared improvements in hearing threshold at different frequencies and recovery rate... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5487696 Mon, 05 Dec 2011 17:33:57 +0100 5487696 http://www.medworm.com/index.php?rid=5477127&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8682222330335030%2F Abstract  To evaluate the relationship between the occurrence of tracheocutaneous fistula of the proximal tracheal stump regarding the indication (therapeutic or prophylactic) of laryngotracheal separation surgery (LTS) and regarding the presence of a current or previous tracheostomy when LTS was performed. Retrospective analysis of 66 patients submitted to LTS. The tracheocutaneous fistula occurred in 14 (21.2%) patients. Twelve (33.3%) of 36 patients whose indication was therapeutic and in two (6.7%) of 30 patients whose indication was prophylactic (p = 0.019). It occurred in 8 (57.1%) of 14 patients who had undergone tracheostomy prior to completion of LTS, while occurred in 6 (11.5%) patients who had not previously undergone tracheostomy (n = 52) (p&n... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477127 Fri, 02 Dec 2011 17:30:43 +0100 5477127 http://www.medworm.com/index.php?rid=5477126&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F835p06q635315h64%2F In conclusion, the DoH guidelines have increased grommets day-case provision and reduced waiting times in both England and Wales, whereas the NICE guidelines have not affected overall levels of grommet insertion in either national cohort. Content Type Journal ArticleCategory OtologyPages 1-4DOI 10.1007/s00405-011-1860-zAuthors Ali Al-Hussaini, Department of Otolaryngology, Head and Neck Surgery, University Hospital of Wales, Cardiff, CF14 4XW UKDavid Owens, Department of Otolaryngology, Head and Neck Surgery, University Hospital of Wales, Cardiff, CF14 4XW UKAlun Tomkinson, Department of Otolaryngology, Head and Neck Surgery, University Hospital of Wales, Cardiff, CF14 4XW UK Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source:... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477126 Fri, 02 Dec 2011 17:30:43 +0100 5477126 http://www.medworm.com/index.php?rid=5477129&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq28578j73x551525%2F The objective of the study was to evaluate the efficacy and the safety of the novel cauterization procedure of the inferior turbinate artery, which may be performed with any kind of inferior turbinate procedures in reducing the intra and the post-operative bleeding in partial inferior turbinectomy. A prospective controlled study was conducted in a referral center. Sixty patients (38M, 22F) who underwent partial turbinectomy were included. In 20 patients, partial turbinectomy was performed with the cauterization in one nasal cavity and the other one without it. The remaining 40 patients were divided into two groups which comprised cauterization positive and negative patients and are assessed in terms of post-operative bleeding. The area of the cauterization was 1 cm2 field which i... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477129 Thu, 01 Dec 2011 19:29:55 +0100 5477129 http://www.medworm.com/index.php?rid=5477128&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9273j091u35557t7%2F Abstract  Neuroblastoma (NB) jaw metastases are rare. Here, we report on cytogenetic and genetic studies on metastatic NB to the mandible. A 7-year-old boy, with an abdominal neuroblastoma, presented with a mass of the left body of the mandible. Cytogenetic analysis of the original tumor and the mandibular lesion biopsies revealed similar heterogenous subclones with 42 ~ 47,XY,+der(1)(q11 → qter),−2,del(7)(q21.1 → qter),−8,−9,−10,−11,del(11)(q13.3 → qter),−13,−14,−15,−17, + 18−18,der(18)(?),+21,+m1,+m2,+m3,+m4,+m5,+m6,+m7[cp25]. The different markers were identified by SKY analysis. Most of the cells carried 3–6 of these translocations: der(1;21), der(2;9;17), der(2;15;18), der(2;15;Y), der(8;10), d... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477128 Thu, 01 Dec 2011 19:29:55 +0100 5477128 http://www.medworm.com/index.php?rid=5477131&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw213104365m22145%2F Abstract  A dysregulation of the cyclooxygenases and a leukotriene/prostaglandin imbalance are assumed to be part of the pathogenesis of the aspirin (ASA) intolerance syndrome. Ozone is an air pollutant with known proinflammatory effects on exposed epithelia, however, its impact on the expression of the cyclooxygenases 1 and 2 (cox1/2) and prostaglandin E2 (PGE2) in the nasal mucosa is not well known. Therefore, we analyzed cox expression and PGE2 levels after ozone exposure in nasal mucosa and in nasal polyps considering ASA intolerance. Isolated epithelial nasal cells from control subjects without chronic rhinosinusitis (CRS), and those from patients with nasal polyps with and without ASA intolerance were cultured and exposed in vitro to ozone. Cox1/2 expression levels were... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477131 Wed, 30 Nov 2011 18:39:53 +0100 5477131 http://www.medworm.com/index.php?rid=5477130&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn10503rr8mjv5k10%2F This study assessed the oncological results in patients undergoing supracricoid laryngectomy with cricohyoidopexy. A cohort of 44 patients surgically treated using supracricoid laryngectomy with cricohyoidopexy between June 2001 and December 2009 was retrospectively analyzed. The mean follow-up period was 53.2 (±24.7) months. The Kaplan–Meier method was used to analyze overall survival and disease-specific survival, as well as survival according to T2 and T3 subgroups. Overall survival rates at 3 and 5 years were 90.5 and 84.1%, respectively. The 3- and 5-year disease-specific survival rates were 95.4 and 92.5%, respectively. Overall survival for patients with T2 disease was 87.5% at 3 years and 80.8% at 5 years. For T3, the corresponding rates were 91.8 and 87.0%. ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477130 Wed, 30 Nov 2011 18:39:53 +0100 5477130 http://www.medworm.com/index.php?rid=5477132&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl6484x568388w348%2F Abstract  Postoperative pain after septorhinoplasty and its optimal management has not been described in detail. Fifty-two adult septorhinoplasty patients were included in a prospective cohort single center study. Patients' and surgical characteristics were evaluated. Outcome and process parameters were analyzed using the questionnaires of the German-wide project Quality Improvement in Postoperative Pain Management (QUIPS) on the first postoperative day. Pain during the first operative day after septorhinoplasty was moderate. Pain management predominately consisted of remifentanil intraoperatively, metamizole in the recovery room, in combination with piritramide in one-third of the patients, and metamizole on ward. Patients younger than 31 years were less satisfied wit... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477132 Wed, 30 Nov 2011 18:39:50 +0100 5477132 http://www.medworm.com/index.php?rid=5477133&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkth4h2842163g333%2F Abstract  The purpose of the study was to evaluate the clinical effects of bicanalicular double silicone stents in endoscopic transnasal dacryocystorhinostomy with lacrimal trephinized canaliculoplasty for monocanalicular and common canalicular obstruction. Bicanalicular double silicone intubation in endoscopic transnasal dacryocystorhinostomy with lacrimal trephination was performed in 58 eyes of 54 patients (5 men, 49 women; mean age: 55.9 ± 14.9 years) with epiphora due to monocanalicular and common canalicular obstruction between November 2007 and August 2010. We reviewed the records of subjects who had undergone the same surgery with a bicanalicular single intubation for same disease between March 2004 and October 2007 as controls (56 eyes of 50 patients... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5477133 Wed, 30 Nov 2011 18:39:49 +0100 5477133 http://www.medworm.com/index.php?rid=5469505&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa474528x55073147%2F In conclusion, we found no evidence supporting the putative link of COL1A1 and COL1A2 alleles with otosclerosis. Content Type Journal ArticleCategory OtologyPages 1-9DOI 10.1007/s00405-011-1859-5Authors Péter Csomor, Department of Otolaryngology and Head and Neck Surgery, Medical and Health Science Center, University of Debrecen, Nagyerdei Krt. 98, Debrecen, 4032 HungaryBalázs Liktor, Department of Otolaryngology, Bajcsy-Zsilinszky Hospital, Budapest, HungaryBálint Liktor, Department of Otolaryngology, Bajcsy-Zsilinszky Hospital, Budapest, HungaryIstván Sziklai, Department of Otolaryngology and Head and Neck Surgery, Medical and Health Science Center, University of Debrecen, Nagyerdei Krt. 98, Debrecen, 4032 HungaryTamás Karosi, Department of Otolaryngology and Head and Neck S... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5469505 Wed, 30 Nov 2011 18:39:46 +0100 5469505 http://www.medworm.com/index.php?rid=5469506&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnq23182w86w116tn%2F Abstract  Our objective was to evaluate single flap with three pedicles, bone paté and split-thickness skin graft for mastoid cavity obliteration after canal wall down mastoidectomy done for chronic suppurative otitis media and its efficacy in producing a small and dry mastoid cavity. Over a period of 7 years (2003–2010), 100 consecutive procedures in 100 patients with chronic suppurative otitis media were performed at the Mansoura University Hospital (Egypt) with a minimum follow-up of 12 months (range 12–72 months). All patients had canal wall down mastoidectomy with simultaneous tympanoplasty. Anteriorly, inferiorly and superiorly pedicled periosteal flap, which was covered by split-thickness skin graft, was used in conjunction with autologous bone pa... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5469506 Wed, 30 Nov 2011 04:53:03 +0100 5469506 http://www.medworm.com/index.php?rid=5458585&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff47567k538666v3t%2F Abstract  There is debate concerning the mechanism of Eustachian tube (ET) ventilation. While a mechanism of complete opening has been advocated previously, sequential contraction of the levator veli palatini and medial pterygoid muscles followed by the tensor veli palatini and lateral pterygoid muscles may produce a transient sequential opening mechanism, allowing an air bolus to traverse the ET. This may explain confusion surrounding sonotubometry reports that not every swallow leads to sound passage in normal subjects. We hypothesize that the ET may not need to open completely when ventilating the middle ear; rather, a discrete air bolus can pass through it. Five normal and five disordered subjects underwent low-radiation dose cine computed tomography (CT) scans of the E... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5458585 Sat, 26 Nov 2011 16:48:42 +0100 5458585 http://www.medworm.com/index.php?rid=5449963&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw5762747j0363w57%2F Abstract  The presenting symptoms of sinonasal lymphoma are usually similar to those of benign inflammatory diseases. Adequate amount of biopsy tissue is required for a definitive diagnosis because tumor coexisting with necrosis or inflammation is not uncommon. Therefore, the diagnosis of sinonasal lymphoma is a challenge for rhinologists. Thirty-two patients diagnosed as having sinonasal lymphoma from 1990 to 2010 in our hospital were included in this study. The presenting symptoms of these patients included nasal obstruction, rhinorrhea, bloody discharge/epistaxis, post nasal drip, facial swelling, neck mass, orbital symptoms, fever, and body weight loss. The average period between patients’ awareness of their symptoms and their decision to seek medical help was 8.9&nbs... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5449963 Fri, 25 Nov 2011 17:56:57 +0100 5449963 http://www.medworm.com/index.php?rid=5449962&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe60710153r788253%2F Abstract  Temporal bone fractures are traditionally classified as transverse, longitudinal or mixed. Since these categories have shown little association with clinical symptoms, new classifications have been introduced, including those related to the involvement of the petrous bone and otic capsule. We have formulated a new classification based on the involvement of four parts of the temporal bone (squama, tympanic, mastoid, and petrous) and assessed which of these classification systems is the most rational using a retrospective chart review in hospital settings (KyungHee Medical Center, Seoul, Korea and Samsung Changwon Hospital, Changwon, Korea). The association between each classification and clinical symptoms was examined by analyzing temporal bone computed tomography ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5449962 Fri, 25 Nov 2011 17:56:57 +0100 5449962 http://www.medworm.com/index.php?rid=5449965&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa376660506w13335%2F We report a 10-year experience in a single institution (La Timone University Hospital of Marseille, France). Among 614 parotidectomies for neoplasms performed from 1998 to 2008, 12 lipomas were identified. A retrospective analysis based on medical records was made. Evaluation, analysis and current management of lipomas of the parotid gland are described. Lipomas accounted for 2% of all parotid neoplasms and 2.6% of benign tumors in our series. The median age of patients was 60 years with a M/F sex ratio of 5–1. The main presentation was a soft asymptomatic, slow-growing, mobile mass although 30% had an indurated mass on palpation. Diagnosis of lipoma, based on the results of imaging, was made preoperatively in all cases. The mean tumor duration prior to excision was 11.5 ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5449965 Thu, 24 Nov 2011 17:50:26 +0100 5449965 http://www.medworm.com/index.php?rid=5449964&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft2502271v4420438%2F In conclusion, there was no association between H. pylori and nasal polyposis in patients without GERD signs or symptoms in our study, and further studies are needed to assess other potential factors that may influence the development of nasal polyposis. Content Type Journal ArticleCategory RhinologyPages 1-5DOI 10.1007/s00405-011-1848-8Authors Shadman Nemati, Department of Otolaryngology, Head and Neck Surgery, Guilan University of Medical Sciences, Rasht, IranAli Mojtahedi, Department of Microbiology, Guilan University of Medical Sciences, Rasht, IranSeyyed Ebrahim Naghavi, Department of Otolaryngology, Head and Neck Surgery, Guilan University of Medical Sciences, Rasht, IranRahmatollah Banan, Department of Otolaryngology, Head and Neck Surgery, Guilan University of Medical Scien... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5449964 Thu, 24 Nov 2011 17:50:26 +0100 5449964 http://www.medworm.com/index.php?rid=5449966&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2008476627628t12%2F Abstract  The decision regarding treatment of early supraglottic carcinoma remains controversial. Single institution clinical data of patients with T2 supraglottic carcinoma treated exclusively with radiotherapy in terms of prognostic factors and treatment results were analyzed. Patient-related factors that would potentially by useful for optimal therapeutic decision to be undertaken were especially investigated. Between 1994 and 2004, 78 patients with T2 supraglottic carcinoma underwent radiotherapy (RT) in Maria Sklodowska-Curie Memorial Cancer Centre and Institute of Oncology, Gliwice Branch, Poland. There were 54 (69%) males and 24 (31%) females in the median age of 61 years. There were 17 (22%) patients with N+. Median body mass of patients before (BM0) and after ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5449966 Thu, 24 Nov 2011 17:50:25 +0100 5449966 http://www.medworm.com/index.php?rid=5449967&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9755v2j12037754w%2F In this study, we designed a “watch window” for monitoring buried free jejunum flaps, thereby allowing us to assess graft viability. From 2007 to 2011, 14 patients with hypopharyngeal cancer underwent circumferential pharyngolaryngectomy that was reconstructed using a free jejunum flap at the Sun Yat-sen University Cancer Centre. During the closing of the neck incision, a “watch window” was designed for postoperative monitoring. Two patients experienced thrombosis of the pedicle. One was detected early and successfully rescued by removal of the thrombosis, the other one managed with a second free jejunum flap. The success rate of the buried flaps was 92.9%. No pharyngocutaneous fistulas or strictures occurred. All patients eventually resumed oral feeding and swallowing. The ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5449967 Thu, 24 Nov 2011 17:50:24 +0100 5449967 http://www.medworm.com/index.php?rid=5441730&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9103u0573214t14w%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-1DOI 10.1007/s00405-011-1841-2Authors Antonio Pirodda, Department of Specialist Surgical and Anesthesiological Sciences, S. Orsola-Malpighi University Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyMaria Chiara Raimondi, Department of Specialist Surgical and Anesthesiological Sciences, S. Orsola-Malpighi University Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, ItalyGian Gaetano Ferri, Department of Specialist Surgical and Anesthesiological Sciences, S. Orsola-Malpighi University Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Ot... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5441730 Mon, 21 Nov 2011 18:09:33 +0100 5441730 http://www.medworm.com/index.php?rid=5441732&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm6k7443353072414%2F This report describes a rare case of histopathologically confirmed glomus faciale tumor. The role of imaging in the differential diagnosis is discussed and therapeutic options are evaluated, along with a review of the previous literature on glomus faciale tumors. A 39-year-old male patient presented with total peripheral facial nerve paralysis. He underwent radical tumor resection and facial nerve grafting for a histopathologically confirmed paraganglioma of the facial nerve. He is now tumor-free after a 4-year follow-up period, and the functional outcome after primary nerve grafting is satisfactory. Facial nerve paragangliomas are a rare cause of facial nerve paralysis. Early imaging using computed tomography and magnetic resonance imaging is essential to clarify the differential di... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5441732 Sat, 19 Nov 2011 16:53:33 +0100 5441732 http://www.medworm.com/index.php?rid=5441731&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Feq5m27h678333410%2F We present a series of patients treated by transoral robotic surgery (TORS) using a new CO2 laser wave guide (CO2 LWG) (Lumenis, Santa Clara, CA). Patients older than 18 years, with malignant pharyngo-laryngeal tumors were enrolled in this prospective study after signing an informed consent. Four patients were enrolled in the study. The mean age was 56 years. One patient had a T1 base of tongue tumor, two patients had supraglottic tumors (T1, T2), and one had a T1 palatine tonsil tumor. All the procedures could be performed using a Maryland forceps, a 0° endoscope and a CO2 LWG introduced via the robotic arm introducer. The laser parameters were: superpulse or continuous mode, 7–15 W, continuous delivery. The average set-up time was 30 min. The average surgical t... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5441731 Sat, 19 Nov 2011 16:53:33 +0100 5441731 http://www.medworm.com/index.php?rid=5441733&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7487qpl007l65666%2F Abstract  Secondary and tertiary hyperparathyroidism (HPT) develop in patients with renal failure due to a variety of mechanisms including increased phosphorus and fibroblast growth factor 23 (FGF23), and decreased calcium and 1,25-dihydroxy vitamin D levels. Patients present with various bone disorders, cardiovascular disease, and typical laboratory abnormalities. Medical treatment consists of controlling hyperphosphatemia, vitamin D/analog and calcium administration, and calcimimetic agents. Improved medical therapies have led to a decrease in the use of parathyroidectomy (PTX). The surgical indications include parathyroid hormone (PTH) levels >800 pg/ml associated with hypercalcemia and/or hyperphosphatemia despite medical therapy. Other indications include calcip... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5441733 Sat, 19 Nov 2011 06:52:23 +0100 5441733 http://www.medworm.com/index.php?rid=5432279&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F262258113tg85818%2F This study reviews the literature and describes the values and limitations of spreader grafts in rhinoplasty and the alternatives to classic spreader grafts. Content Type Journal ArticleCategory Review ArticlePages 1-6DOI 10.1007/s00405-011-1837-yAuthors A. Teymoortash, Department of Otolaryngology, Head and Neck Surgery, Philipp University, Baldinger Str., 35043 Marburg, GermanyJ. A. Fasunla, Department of Otolaryngology, Head and Neck Surgery, Philipp University, Baldinger Str., 35043 Marburg, GermanyA. A. Sazgar, Department of Otolaryngology, Head and Neck Surgery, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngo... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5432279 Fri, 18 Nov 2011 17:31:48 +0100 5432279 http://www.medworm.com/index.php?rid=5432280&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd6654137k83x2558%2F Abstract  It has been a common practice among the oncologist to reduce the dosage of adjuvant radiotherapy for patients after free jejunal flap reconstruction. The current aims to study potential risk of radiation to the visceral flap and the subsequent oncological outcome. Between 1996 and 2010, consecutive patients with carcinoma of the hypopharynx requiring laryngectomy, circumferential pharyngectomy and post-operative irradiation were recruited. Ninety-six patients were recruited. TNM tumor staging at presentation was: stage II (40.6%), stage III (34.4%) and stage IV (25.0%). Median follow-up period after surgery was 68 months. After tumor ablation, reconstruction was performed using free jejunal flap (60.4%), pectoralis major myocutaneous (PM) flap (31.3%) and fre... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5432280 Fri, 18 Nov 2011 06:58:19 +0100 5432280 http://www.medworm.com/index.php?rid=5422762&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff83165g7wj814332%2F Abstract  Surgery of the posterior ethmoid and sphenoid sinuses can be challenging. In 1999, a technique was described for identification of the superior turbinate and utilizing it as a landmark in endoscopic posterior ethmoidectomy and sphenoidotomy. Although this was more than a decade ago, it has not been supported by further studies. In our practice, we have routinely adopted this technique, and have modified it to allow further orientation during endoscopic surgery of the posterior sinuses. To describe a review of our technique, and to prospectively assess the value of the superior turbinate as a useful landmark during endoscopic posterior ethmoidectomy and sphenoidotomy. Fifty patients listed for endoscopic posterior ethmoidectomy with or without sphenoidotomy were in... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5422762 Tue, 15 Nov 2011 16:57:02 +0100 5422762 http://www.medworm.com/index.php?rid=5409223&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F732tt446wn424560%2F Abstract  The aim of this study was to confirm the feasibility of high signal on three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging (3D FLAIR MRI) as one of the prognostic factors in recovery of sudden idiopathic hearing loss. A retrospective study was conducted using patients who were diagnosed with unilateral sudden idiopathic hearing loss from January 2008 to December 2010. A total of 120 patients were enrolled in for this study. High-intensity signal in the inner ear on precontrast 3D FLAIR MRI was observed in 31 patients (25.8%; FHS) and labyrinthine enhancement was not observed in another 89 patients (FNS; 74.2%). There was no significant difference in patients’ characteristics between two groups except final hearing. Final puretone ave... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409223 Mon, 14 Nov 2011 16:53:29 +0100 5409223 http://www.medworm.com/index.php?rid=5409222&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff115333q0401m01r%2F Abstract  Epidemiological data of Bell’s palsy (BP) have been reported. For example, the annual incidence of BP is 15–30 per 100,000 persons, with equal numbers of men and women affected, and there is no predilection for either side of the face. However, details of the relationship between BP and morphometric aspects of the facial nerve have not been available in textbooks. We performed a morphometric analysis of human facial nerve fibers and estimated the total number of myelinated axons (TN) and average transverse area of myelinated axons (ATA). The facial nerve showed a significant decrease of TN with increasing age (r = −0.77; p < 0.01), but showed no significant changes of ATA with age (r = −0.01; p = 0.96). We supposed... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409222 Mon, 14 Nov 2011 16:53:29 +0100 5409222 http://www.medworm.com/index.php?rid=5409224&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffg0u260w83167x32%2F This article reviews the experience to date with the use of molecular markers for the prognostic evaluation of laryngeal epithelial precursor lesions. We conducted a thorough review of the published literature to identify those studies using biomarkers to predict malignant progression of laryngeal epithelial precursor lesions. Of the 336 studies identified in this systematic search, 15 met the inclusion criteria and form the basis of this review. Limited studies suggest that certain biomarkers are potentially reliable predictors of malignant progression including various regulators of cell adhesion and invasion (e.g. FAK, cortactin, osteopontin, and CD44v6) and proliferation-associated markers such as TGF-βRII and Kv3.4. The predictive value of these markers, however, has yet to be ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409224 Fri, 11 Nov 2011 12:46:37 +0100 5409224 http://www.medworm.com/index.php?rid=5409225&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmt785qm127156153%2F In conclusion, cross-reactivity to tropomyosin in house dust mite allergic patients in southern Bavaria, Germany is rarer than suspected. Beside the direct allergic reactions, a further part of reactions to seafood must therefore be ascribed to other mechanisms such as intoxication or intolerance to, e.g. additives in the food product. Content Type Journal ArticleCategory MiscellaneousPages 1-6DOI 10.1007/s00405-011-1826-1Authors Sven Becker, Department of Otorhinolaryngology-Head and Neck Surgery, Ludwig Maximilian University, Marchioninistrasse 15, 81377 Munich, GermanyMoritz Gröger, Department of Otorhinolaryngology-Head and Neck Surgery, Ludwig Maximilian University, Marchioninistrasse 15, 81377 Munich, GermanyMartin Canis, Department of Otorhinolaryngology-Head and Neck Sur... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409225 Fri, 11 Nov 2011 12:46:35 +0100 5409225 http://www.medworm.com/index.php?rid=5409226&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F563181187gn41778%2F In conclusion, endovascular treatment of life-threatening postsurgical haemorrhages should be considered if the source of bleeding is unknown or if surgery is difficult and may result in devastating postoperative complications. Content Type Journal ArticleCategory Head and NeckPages 1-7DOI 10.1007/s00405-011-1823-4Authors Andreas Schrock, Department of Otolaryngology, Head and Neck Surgery, Universität Bonn Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde/Chirurgie, Sigmund-Freud Straße 25, 53127 Bonn, GermanyMark Jakob, Department of Otolaryngology, Head and Neck Surgery, Universität Bonn Klinik und Poliklinik für Hals-Nasen-Ohrenheilkunde/Chirurgie, Sigmund-Freud Straße 25, 53127 Bonn, GermanyKatharina Strach, Department of Radiology, University of Bonn, Bonn, GermanyBen... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409226 Fri, 11 Nov 2011 12:46:33 +0100 5409226 http://www.medworm.com/index.php?rid=5409227&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc8457vv7q7g36r21%2F In conclusion, the suggested therapeutic management may be considered in <1 mm melanomas without taking further unnecessary oncologic risks. Content Type Journal ArticleCategory Head and NeckPages 1-6DOI 10.1007/s00405-011-1827-0Authors L. Sartore, Institute of Plastic Surgery, Padua University Hospital, 2 Giustiniani Street, 35128 Padua, ItalyG. Giatsidis, Institute of Plastic Surgery, Padua University Hospital, 2 Giustiniani Street, 35128 Padua, ItalyF. Reho, Institute of Plastic Surgery, Padua University Hospital, 2 Giustiniani Street, 35128 Padua, ItalyG. Tanzillo, Institute of Plastic Surgery, Padua University Hospital, 2 Giustiniani Street, 35128 Padua, ItalyL. Campana, Sarcoma and Melanoma Unit, Oncological Institute of Veneto, Padua, ItalyR. Salmaso, Pathology Insti... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409227 Fri, 11 Nov 2011 12:46:32 +0100 5409227 http://www.medworm.com/index.php?rid=5409228&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq65561l23ug3064x%2F Abstract  The focus of this study was to compare the role of nerve growth factor (NGF) and vascular endothelial growth factor (VEGF) in the regeneration of experimental skin and cartilage trauma. The role of VEGF in this process is known since decade; the NGF participation on this process has been first discussed within the spinal cord injury repair. We hypothesized that both VEGF and NGF induce angiogenesis and take part on the repair process. The angiogenesis response and the cartilage regeneration after phVEGF165 plasmid and rat pcNGF plasmid administration were investigated using BALB/c mice. PhVEGF165 and pcNFG were injected into the right mice ear and plain vector injection into the left ear the day before trauma. The next day, all mice were ear-punched, resulting in 2... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409228 Wed, 09 Nov 2011 17:45:53 +0100 5409228 http://www.medworm.com/index.php?rid=5409229&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7636748716p3874v%2F In conclusion, intractable neck masses and an abscess can be the initial finding in tularemia, and a high index of suspicion is needed in the differential diagnosis. Superselective neck dissection is a safe and effective option in the treatment of long lasting cervical tularemia unless it responds to medical treatment. Content Type Journal ArticleCategory MiscellaneousPages 1-6DOI 10.1007/s00405-011-1830-5Authors Yusuf Kızıl, Department of Otorhinolaryngology, Gazi University School of Medicine, Ankara, TurkeyUtku Aydil, Department of Otorhinolaryngology, Gazi University School of Medicine, Ankara, TurkeySüleyman Cebeci, Department of Otorhinolaryngology, Gazi University School of Medicine, Ankara, TurkeyOsman Tuğrul Güzeldir, Department of Otorhinolaryngology, Gazi Universi... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5409229 Wed, 09 Nov 2011 07:03:25 +0100 5409229 http://www.medworm.com/index.php?rid=5388256&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc6ln515011052685%2F We described our experience on EEDCR, including the main advantages and disadvantages of it. Hundred consecutive cases of lachrymal problems underwent EEDCR utilizing simple punch removal of bone, instead of powered instrumentation or lasers. The medial aspect of the sac was removed in all of patients, while preserving normal mucosa around the sac. Hundred cases of EEDCR were performed on 81 patients, with 19 bilateral procedures. Nine procedures were performed under local anesthesia. Based on a mean 14 months follow-up, 95 cases were free of symptoms, revealing 95% success rate. The punch technique diminishes the expenses of powered or laser instrumentation with comparable results. It seems that preserving normal tissues and creating a patent rhinostomy with least surgical trau... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388256 Mon, 07 Nov 2011 17:14:44 +0100 5388256 http://www.medworm.com/index.php?rid=5388258&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm201527213154k62%2F This study confirms the incidence of olfactory disorder in MS-patients and reveals a frequent gustatory deficit. The Identification subtest can be proposed as a marker of the OF in MS-patients: it includes complex cognitive tasks and may be influenced by depression and fatigue, which are common symptoms of MS. It inversely correlates with the disability status. Content Type Journal ArticleCategory RhinologyPages 1-7DOI 10.1007/s00405-011-1812-7Authors Sarah Bettina Dahlslett, Department of Otorhinolaryngology, Head and Neck Surgery, Special Consulting Service for Smell Disorders, Charité, University of Berlin, Charité Campus Mitte, Charitéplatz 1, 10117 Berlin, GermanyOender Goektas, Department of Otorhinolaryngology, Head and Neck Surgery, Special Consulting Service for Smell ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388258 Sat, 05 Nov 2011 17:10:37 +0100 5388258 http://www.medworm.com/index.php?rid=5388257&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw1t7hp3k46511426%2F We present the first series of patients treated by transoral laser surgery (TLS) using the new AcuPulse 40WG CO2 laser with the FiberLase flexible waveguide (CO2 LWG) (Lumenis, Santa Clara, CA) with the objective to test its reliability and efficacy. Patients older than 18 years, with oral, pharyngo-laryngeal or tracheal benign or premalignant lesions were enrolled after signing an informed consent. This prospective study was conducted between October 2010 and May 2011 in two tertiary care university hospitals. Thirty-nine patients were enrolled in the study. The mean age was 47.9 years (range 18–86 years). There were 21 women and 18 men. Thirteen patients had hypertrophy of lymphoid tissue (palatine and or lingual), nine patients had granulomas, four patients had an e... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388257 Sat, 05 Nov 2011 17:10:37 +0100 5388257 http://www.medworm.com/index.php?rid=5388259&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5h66t422300jh1q6%2F Abstract  Analysis of spontaneous nystagmus is important in the evaluation of dizzy patients. The aim was to measure how different visual conditions affect the properties of nystagmus using three-dimensional video-oculography (VOG). We compared prevalence, frequency and slow phase velocity (SPV) of the spontaneous nystagmus with gaze fixation allowed, with Frenzel’s glasses, and in total darkness. Twenty-five patients (35 measurements) with the peripheral vestibular pathologies were included. The prevalence of nystagmus with the gaze fixation was 40%, and it increased significantly to 66% with Frenzel’s glasses and regular room lights on (p < 0.01). The prevalence increased significantly to 83% when the regular room lights were switched off (p = 0.... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388259 Sat, 05 Nov 2011 17:10:35 +0100 5388259 http://www.medworm.com/index.php?rid=5388260&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj786635543utr860%2F The objective of this review was to systematically analyze the available information in the literatures regarding the postural control, motor skills, and health-related quality of life in children with hearing impairment. Searches of data sources PubMed, MEDLINE, CINHAL, EMBASE, SCOPUS, ISI of web science, Cochrane Library, and AMED database were performed from the earliest to 7 February 2011. Study eligibility criteria included non-interventional studies that addressed postural control, motor skills, and health-related quality of life in children with hearing impairment. For each eligible article, data were extracted using custom-designed forms by a single investigator. Collected data included study demographics, study design, study population, sample size, outcome measures, and res... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388260 Fri, 04 Nov 2011 16:55:08 +0100 5388260 http://www.medworm.com/index.php?rid=5388261&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6l610526p4438717%2F Abstract  Since inner ear hair cells are mechano-electric transducers the control of hydrostatic pressure in the inner ear is crucial. Most studies analyzing dynamics and regulation of inner ear hydrostatic pressure performed pressure measurements in the cochlea. The present study is the first one reporting about absolute hydrostatic pressure values in the labyrinth. Hydrostatic pressure of the endolymphatic system was recorded in all three semicircular canals. Mean pressure values were 4.06 cmH2O ± 0.61 in the posterior, 3.36 cmH2O ± 0.94 in the anterior and 3.85 cmH2O ± 1.38 in the lateral semicircular canal. Overall hydrostatic pressure in the vestibular organ was 3.76 cmH2O ± 0.36. Endolymphatic hydrostatic pr... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388261 Tue, 01 Nov 2011 16:51:34 +0100 5388261 http://www.medworm.com/index.php?rid=5388262&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd7414885kx2t45g3%2F Abstract  Eosinophilic chronic rhinosinusitis (ECRS) largely consists of allergic fungal sinusitis, non-allergic fungal rhinosinusitis, aspirin-exacerbated ECRS, and superantigen-induced ECRS. The pathophysiology of ECRS is not completely understood, in particular, the role of mycotoxins remains unknown. The aim of this study was to evaluate the effects of one of the most widespread mycotoxin, ochratoxin A (OTA), on the release of pro-inflammatory cytokines such as interleukin-(IL)-6 and the CXC-chemokine IL-8 from nasal epithelial cell cultures (NEC) of subjects with and without ECRS. NEC (ECRS group: n = 16; controls: n = 7) were stimulated with OTA for 24 h. Protein concentrations of IL-6 and IL-8 levels were measured in NEC supernatants by ELISA ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388262 Tue, 01 Nov 2011 16:51:33 +0100 5388262 http://www.medworm.com/index.php?rid=5388263&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp644850x7u424522%2F Abstract  The aims of the article were to study the clinical characteristic of patients with pseudocysts and to compare different common modalities of treatment and introduce the concept of observation in pseudocyst management. Twenty-eight patients were diagnosed with pseudocyst of the auricle between June 2009 and June 2011 in a medical college hospital. The patients were divided into four groups each of seven patients on the basis of primary treatment offered. Four primary treatments offered were simple aspiration, aspiration with intralesional steroid, incision and drainage with removal of anterior cartilage leaflet with buttoning, and lastly, simple observation and reassurance. All 28 patients were male with involvement of right side more than left and no one had bilat... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388263 Mon, 31 Oct 2011 16:58:27 +0100 5388263 http://www.medworm.com/index.php?rid=5388266&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn84475g353252500%2F Abstract  This retrospective study aimed to compare the accuracy of two nodal evaluation criteria using computed tomography after intra-arterial chemoradiation in node-positive head and neck squamous cell carcinomas. Computed tomography was used to evaluate radiographic nodal response 4–8 weeks after intra-arterial chemoradiation. We compared the accuracy of two different criteria: criterion 1 (radiographic complete response was recorded in the absence of focal abnormalities and if the maximum diameter of the metastatic node was less than 15 mm), and criterion 2 (radiographic complete response was recorded in the absence of focal abnormalities and if the minimum diameter of metastatic nodes was less than 7 mm in level II and if the minimum diameter of metast... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388266 Mon, 31 Oct 2011 16:58:26 +0100 5388266 http://www.medworm.com/index.php?rid=5388265&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnk3mk4686w9137r1%2F In conclusion, we find that Cochlear implantation is a safe low-morbility technique with a relatively low complication rate in the presented population. Content Type Journal ArticleCategory OtologyPages 1-5DOI 10.1007/s00405-011-1818-1Authors A. Ciorba, Audiology Department, University Hospital of Ferrara, C.so Giovecca 203, Ferrara, ItalyR. Bovo, Audiology Department, University Hospital of Ferrara, C.so Giovecca 203, Ferrara, ItalyP. Trevisi, Audiology Department, University Hospital of Ferrara, C.so Giovecca 203, Ferrara, ItalyM. Rosignoli, Audiology Department, University Hospital of Ferrara, C.so Giovecca 203, Ferrara, ItalyC. Aimoni, Audiology Department, University Hospital of Ferrara, C.so Giovecca 203, Ferrara, ItalyA. Castiglione, Audiology Department, University Hospital... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388265 Mon, 31 Oct 2011 16:58:26 +0100 5388265 http://www.medworm.com/index.php?rid=5388264&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F77uq20r21t288174%2F Abstract  The aim of this pilot study was to investigate olfactory function in unselected, cooperative patients with ischemic stroke and to gain information about olfactory perception in patients with distinct stroke localizations. Three ischemic stroke patients underwent olfactory testing using the Sniffin’ Sticks test and olfactory event-related potentials recording. All stroke patients were found to be normosmic or only slightly hyposmic when using a psychophysical testing device with age-adjusted norms. No responses or longer latencies on the affected side were found, however, when recording evoked potentials. This seems to argue for the idea that on the affected side it is often possible to document the objective lesion although the subjective perception of the patien... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5388264 Mon, 31 Oct 2011 16:58:26 +0100 5388264 http://www.medworm.com/index.php?rid=5361619&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1407m211520mr6w1%2F Abstract  The aim of this study was to compare the efficacy and safety of a topical suspension of bacterial antigens for the management of chronic suppurative otitis media (CSOM). Two-hundred ten patients with CSOM were enrolled in this study. The patients were divided into two numerically equal groups and randomized to receive a topical suspension of bacterial antigens, Lantigen B (group A), or placebo (group B), according to the following protocol: 5 drops thrice a day for 12 consecutive weeks in the external acoustic duct. The topical suspension of bacterial antigens and placebo were administered by identical, anonymous dispensers in order to maintain double-blind conditions. Before, at the end and 3 months, and after the end of the treatment, all patients who enter... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361619 Sat, 29 Oct 2011 05:47:46 +0100 5361619 http://www.medworm.com/index.php?rid=5361620&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg6k8p1122m2l9806%2F Abstract  We wanted to explore how many patients will undergo tonsillectomy during the first 5 years after peritonsillar abscess or peritonsillar cellulitis, and why. In addition we sought predictive factors as to who would benefit from tonsillectomy. Medical records of 809 patients with peritonsillar infection (ICD-10 J36) aged over six were analyzed, and data on the history of tonsil infections and differences in treatment were collected. Data on patients who underwent tonsillectomy during the next 5 years were compared with data on patients needing no tonsillectomy. An abscess or planned interval tonsillectomy was performed on 159 patients. Of the conservatively treated 7- to 16.9-year-old patients, 42.5% required surgery later, of those aged 17–29.9 year... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361620 Sat, 29 Oct 2011 05:47:45 +0100 5361620 http://www.medworm.com/index.php?rid=5361621&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0r5202164522j01u%2F Abstract  The aim of this study was to investigate the relationship between the subjective Epworth Sleepiness Scale (ESS) and objective polysomnographic parameters that was compared in dichotomized groups of obstructive sleep apnea (OSA) patients with and without excessive daytime sleepiness (EDS). A retrospective review of the 96 consecutive snoring patients suspected of OSA due to upper airway problems was performed. ESS score was assessed and EDS was considered present when the ESS score was >10. Polysomnography was performed for each patient. Comparisons of polysomnographic parameters between both groups of patients were performed using Mann–Whitney U-tests. The Pearson’s correlation coefficient was calculated. EDS patients showed significantly greater body mass i... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361621 Sat, 29 Oct 2011 05:47:44 +0100 5361621 http://www.medworm.com/index.php?rid=5361624&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe31492q3109x633l%2F In conclusion, this study determines the importance of connexin 26 mutations in Bulgarian children with severe to profound congenital nonsyndromic sensorineural hearing loss, the prevalence of the different mutation variants and their relationship with the ethnical background of the patients. In addition, we report for the first time a novel mutation in the GJB2 gene. Content Type Journal ArticleCategory OtologyPages 1-4DOI 10.1007/s00405-011-1817-2Authors Diana P. Popova, Department of ENT, Medical University Sofia, Blvd. “Han Pagan” 1, 1680 Sofia, BulgariaRadka Kaneva, Molecular Medicine Center, Medical University Sofia, Sofia, BulgariaSonya Varbanova, Department of ENT, Medical University Sofia, Blvd. “Han Pagan” 1, 1680 Sofia, BulgariaTodor M. Popov, Department of ENT... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361624 Sat, 29 Oct 2011 05:47:43 +0100 5361624 http://www.medworm.com/index.php?rid=5361623&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn5v653k608167168%2F Abstract  The aim of this study was to investigate audio-vestibular function in patients with essential tremor. Twenty-three patients with essential tremor (46 ears) and 21 health control subjects (42 ears) were included in the present study. Patients and comparison subjects were matched for age and gender. All patient and control subjects underwent pure tone audiometric test, tympanogram, transient-evoked otoacoustic emissions and auditory brainstem response. Vestibular system was evaluated by bitermal caloric test. Comparison of variables between the groups was performed. Investigation of the relationship between parameters about ET disease and hearing levels were also studied. Pure tone thresholds significantly differed between patients and controls in 250 and 500 H... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361623 Sat, 29 Oct 2011 05:47:43 +0100 5361623 http://www.medworm.com/index.php?rid=5361622&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F725t5w9x42282237%2F Abstract  The aim of this study was to investigate the relationship between the amount of bleeding and bacteremia during nasal septal surgery. Seventy-one patients undergoing septoplasty were enrolled in the present study. The amount of bleeding was measured and recorded for each patient. Preoperative and postoperative blood cultures were collected immediately after the induction of anesthesia and 20 min after the operation, respectively. While none of the blood cultures taken preoperatively were positive for any organism, the cultures obtained postoperatively were positive in 9 (12.7%) of 71 patients who underwent septoplasty, and bacteremia was more frequent among those with a greater amount of bleeding during the surgery. The results of this study suggest that althou... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361622 Sat, 29 Oct 2011 05:47:43 +0100 5361622 http://www.medworm.com/index.php?rid=5361625&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fku473057147x5811%2F This study was done to determine the influence of passive smoking on S. pneumoniae, H. influenzae, and M. catarrhalis colonization rates among children. This is a prospective cross-sectional study. Tertiary referral centers with accredited otorhinolaryngology-head and neck surgery and Microbiology Departments. In this cross-sectional study, 2–6 years old children in 10 randomly selected day-care centers in northeast of Iran (Mashad) were studied. Smoking exposure and medical history were recorded. Carriage rates for aforementioned bacteria were analyzed on the basis of smoking exposure. 1,125 children (Female/Male: 597/528) with the mean age of 5.05 ± 0.98 years were studied. Carriage rates of S. pneumoniae, H. influenzae and M. catarrhalis among children were 10... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361625 Fri, 28 Oct 2011 05:49:15 +0100 5361625 http://www.medworm.com/index.php?rid=5361626&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj65072638551h721%2F Abstract  An important function of the healthy nose is the ability to adjust nasal patency in response to stimuli such as a change in posture between sitting and supine. We hypothesised that the regulation of nasal patency would be impaired in patients with asthma and mild rhinitis and that it could be improved by reducing nasal inflammation with a topical nasal steroid. This is a randomised, placebo-controlled, double-blind, cross-over study comprising 19 subjects with well-controlled asthma and a history of rhinitis without current treatment. The subjects were randomised to fluticasone propionate aqueous nasal spray (Beconase®), 200 μg daily, or placebo (FESS® saline nasal spray), for 6 weeks in a cross-over design with a 4-week wash-out between treatments. Na... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5361626 Fri, 28 Oct 2011 05:49:14 +0100 5361626 http://www.medworm.com/index.php?rid=5348576&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7447325711810801%2F Abstract  We aimed to characterize somatic mutations in the D-loop of mitochondrial DNA (mtDNA) and their impact on survival in oral squamous cell carcinoma patients in an endemic betel quid chewing area. Histologically confirmed oral cancer and corresponding non-tumor tissues were obtained from 59 patients. The D-loop of mtDNA sequence in a patient’s non-cancerous tissues was compared with that of paired oral cancer samples and any sequence differences were identified as somatic mutations. With a median follow-up of 16 months, somatic mutations of the D-loop were observed in 38 (64.4%) patients and most of them occurred in the poly-C tract. There was no significant difference between the mutation group and non-mutation group in age, gender, primary site, histologica... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5348576 Fri, 21 Oct 2011 15:59:28 +0100 5348576 http://www.medworm.com/index.php?rid=5348577&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnj585031p27h2673%2F Content Type Journal ArticleCategory EditorialPages 1-2DOI 10.1007/s00405-011-1804-7Authors Robin E. A. Tjon Pian Gi, Department of Otorhinolaryngology, University of Groningen, University Medical Center Groningen, P.O. Box 30.001, 9700RB Groningen, NetherlandsAndreas Dietz, Department of Otorhinolaryngology, University of Leipzig, Leipzig, GermanyVojko Djukic, Department of Otorhinolaryngology, Medical Center, University of Belgrade, Belgrade, YugoslaviaHans E. Eckel, Department of Otorhinolaryngology, Klinikum Klagenfurt, Klagenfurt am Wörthersee, AustriaGerhard Friedrich, Department of Otorhinolaryngology, Medical University of Graz, Graz, AustriaWojciech Golusinski, Department of Otorhinolaryngology, Greater Poland Cancer Centre, Poznan, PolandAnastasios Hantzakos, Department of O... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5348577 Fri, 21 Oct 2011 15:59:27 +0100 5348577 http://www.medworm.com/index.php?rid=5348579&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd717135x16200427%2F Content Type Journal ArticleCategory EditorialPages 1-4DOI 10.1007/s00405-011-1794-5Authors J. A. Smith, Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital, Birmingham, UKJ. C. Watkinson, Otolaryngology Head and Neck Surgery, Queen Elizabeth Hospital, Birmingham, UKA. Shaha, Head and Neck Service, Memorial Sloan-Kettering Cancer Center, New York, USA Journal European Archives of Oto-Rhino-LaryngologyOnline ISSN 1434-4726Print ISSN 0937-4477 (Source: European Archives of Oto-Rhino-Laryngology) European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5348579 Fri, 21 Oct 2011 15:59:26 +0100 5348579 http://www.medworm.com/index.php?rid=5348578&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F661828tqu193l531%2F This study attempted to explore suitable anesthetic methods used for removal of tracheobronchial foreign body (FB) via self-retaining laryngoscopy and Hopkins telescopy in children. 92 cases had undergone FB removal via self-retaining laryngoscopy and Hopkins telescopy or rigid bronchoscopy in our hospital since 2006, of which 56 cases were under intravenous anesthesia and endotracheal intubation with muscle relaxation (IAEI with MR), and the other 36 cases were under intravenous anesthesia with spontaneous breathing (IASB). Operative parameters and intraoperative vital signs were analyzed. Tracheobronchial foreign body was successfully removed in 87 cases, and not found in the other 5 cases. SpO2 was below 90% transiently in 41 cases, 29 cases of which were under IAEI with MR and 12 ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5348578 Fri, 21 Oct 2011 15:59:26 +0100 5348578 http://www.medworm.com/index.php?rid=5348580&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh111331176003856%2F Abstract  Metastasis to regional lymph nodes constitutes the main route toward progression and dissemination of head and neck carcinoma; at the same time it is the most significant adverse prognostic indicator for this disease. In recent years, significant focus has been given on the molecular mechanisms behind lymph node metastasis of head and neck cancer. The aim of this study is to assess the role of growth factor expression and function in association with lymph node metastasis and overall prognosis of head and neck cancer. Current literature, searching for experimental data regarding the molecular pathways of lymph node dissemination of head and neck cancer, is reviewed giving special emphasis on the expression and prognostic significance of specific growth factors. Me... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5348580 Thu, 20 Oct 2011 15:51:16 +0100 5348580 http://www.medworm.com/index.php?rid=5348581&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg5hnpu4x4lr38071%2F Abstract  Benzocaine lozenges are popular in symptomatic treatment of acute sore throat. The aim of this study was to evaluate if sucking a benzocaine lozenge was superior to a placebo lozenge in patients with pain while swallowing. Volunteers with acute, uncomplicated sore throat received randomly and double-blind either a benzocaine 8 mg or a placebo lozenge. Pain was assessed on a numerical visual rating scale. The primary outcome measure was the sum of the pain intensity differences (SPID) over 2 h. Secondary outcome measures included the number of patients who reported 50% or more of their baseline pain score (responders) and those with worthwhile and complete pain relief, the times to worthwhile/complete pain relief and to pain recurrence and the occurrence ... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5348581 Thu, 20 Oct 2011 15:51:14 +0100 5348581 http://www.medworm.com/index.php?rid=5324468&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9671125258824832%2F Abstract  The purpose of this study was to evaluate microarray technology of HNSCC cells in muscle tissue. 200 SCCVII tumor cells were injected intramuscularly into the right flank of ten C3H/Km mice each. One week later the animals were killed and the tissue taken out. Histology (H&E staining) and microarray of the tissue were performed. Histology showed a few tumor cells between the muscle fibers. Microarray technology showed different gene expression pattern of the muscle tissue with SCCVII cells in comparison with normal muscle tissue. Only those genes showing a fold change difference of 5 or higher were considered. Gene expression analysis revealed changes in the expression levels of SCCVII cells in muscle tissue in 220 genes. Significant gene expression differences be... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5324468 Sat, 15 Oct 2011 05:53:18 +0100 5324468 http://www.medworm.com/index.php?rid=5324469&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg11j63j162r35502%2F This study revealed that age and RDI were risk factors in development of daytime hypertension. For patients with mild to moderate OSA, SBP was significantly worse when getting older and for patients with nonapnea and mild to moderate OSA, DBP was significantly worse with increasing age. Level of evidence N/A. Content Type Journal ArticleCategory Head and NeckPages 1-6DOI 10.1007/s00405-011-1800-yAuthors Chun-Chih Chao, Department of Otolaryngology, Tainan Municipal Hospital, Tainan, TaiwanJiunn-Liang Wu, Department of Otolaryngology, Medicine College and Hospital, National Cheng Kung University, Tainan, TaiwanYu-Tuan Chang, Department of Otolaryngology, Tainan Municipal Hospital, Tainan, TaiwanCheng-Yu Lin, Department of Otolaryngology, Medicine College and Hospital, National Chen... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5324469 Sat, 15 Oct 2011 05:53:17 +0100 5324469 http://www.medworm.com/index.php?rid=5324470&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv54551u2u37704v5%2F Abstract  Bispectral index (BIS) monitor is a neurophysiological monitoring device which continually analyses a patient’s electroencephalogram during sedation and general anaesthesia to assess the level of consciousness and depth of anaesthesia. BIS monitoring, whilst performing sleep nasendoscopy (using midazolam and propofol), has helped validate depth of sedation and allowed comparison with levels of sedation of control patients during natural sleep. A prospective study of 30 patients with snoring undergoing sleep nasendoscopy with BIS monitoring was conducted. BIS monitoring was recorded throughout the procedure and assessment of snoring was made at the appropriate level of sedation and snoring. BIS values were compared with control patients. The 30 patients undergoin... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5324470 Thu, 13 Oct 2011 05:48:37 +0100 5324470 http://www.medworm.com/index.php?rid=5315252&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd091441156873074%2F Abstract  Recurrence of secondary hyperparathyroidism (rSHPT) in patients after total parathyroidectomy (TPTX) with autotransplantation (AT) represents a major diagnostic and therapeutic challenge. The aim of this retrospective cohort study was to evaluate rSHPT in patients after TPTX with AT and the subsequent surgical treatment. 112 patients with secondary hyperparathyroidism (surgery 1998–2008) were evaluated. In 16 patients, rSHPT was detected, while all of them had been originally operated with TPTX, cervical thymectomy and AT. The recurrence rate of TPTX with AT in our patient cohort was 14.2% (16/112). All the 16 patients with rSHPT suffered from forearm-autotransplant(s) hyperparathyroidism (AT-HPT). AT-HPT was diagnosed after a median of 5.6 years (1.5–11&... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5315252 Wed, 12 Oct 2011 05:42:56 +0100 5315252 http://www.medworm.com/index.php?rid=5315254&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F47172j8670331t66%2F The objective of this study was to assess the auditory performance of the neural structures in response to controlled electrical stimulation period. A prospective cohort study focused on the intracochlear electrical stimulation parameters and hearing performance of patients suffering different cochlear malformations who were treated by cochlear implants constituted the study design. The study sample constituted 16 patients, suffering profound prelingual hearing impairment, diagnosed on the basis of radiological criteria as having an inner ear malformation, and who underwent cochlear implantation and were followed for 24 months. Patients with common cavities, characterized by fewer nerve structures involved, less epithelial penetration, and deficient cochlear tonotopy distributio... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5315254 Wed, 12 Oct 2011 05:42:55 +0100 5315254 http://www.medworm.com/index.php?rid=5315253&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv3kj244856776424%2F Abstract  When treating head and neck cancer of an advanced stage, additional therapy modalities are often combined with surgery. This sets new challenges for the reconstructive surgery, especially after segmental mandibulectomy. There is continuous discussion considering the optimal timing of the surgery with relation to other treatment methods such as radiation therapy and chemotherapy. In this work, we have analyzed a series of 10 patients treated with segmental mandibulectomy and preoperative irradiation or chemoradiation in our institute between 1999 and 2006. Surgery was scheduled within 5 weeks from the radiation therapy. 9 out of 10 reconstruction flaps were vital at the last follow-up. In general the outcome of these patients was consistent with the results pu... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5315253 Wed, 12 Oct 2011 05:42:55 +0100 5315253 http://www.medworm.com/index.php?rid=5315255&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu12754146u604870%2F Abstract  The aim of this study was to compare the incidence of complications of endoscopic sinus surgery (ESS) to the incidence of complications of traditional and microscopic sinus surgery. A meta-analysis was carried out on 28 series of patients (a total of 13,405) who had undergone ESS, 8 series of patients (3,887 in total) who had undergone traditional endonasal sinus surgery and 7 series of patients (1,630 in total) who had undergone microscopic sinus surgery. The authors used the Bayesian inference package WinBUGS operating from within the statistical computer program R (version 2.7.1). Major complications had a higher incidence after traditional sinus surgery than ESS but this fact did not cause a significant statistical difference, whereas microscopic surgery had s... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5315255 Sun, 09 Oct 2011 05:36:16 +0100 5315255 http://www.medworm.com/index.php?rid=5315256&cid=s_33412_16_f&fid=33412&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F31m6926177l65725%2F Abstract  Lateralization of primary epistaxis was prospectively studied in 326 patients at Radebeul Elblandklinikum. The male–female-ratio was 1.3:1. A slight dominance of the right side (45% right vs. 39% left) was found in all patients. Further analyzed were the relationship to the localization of bleeding (anterior or posterior), the age and possible causes or risk factors. Nose bleeding from the posterior nasal portion appears to be statistically significantly higher than on both sides of anterior epistaxis. No statistically significant age dependence of laterality of epistaxis was observed in the age groups which we selected. However, nosebleed appears more frequently in women under the age of 50 years in both nostrils. With identified risk factors, idiopathic e... European Archives of Oto-Rhino-Laryngology journals http://www.medworm.com/rss/comments.php?id=5315256 Sun, 09 Oct 2011 05:36:14 +0100 5315256