European Heart Journal via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'European Heart Journal' source. Sat, 13 Mar 2010 13:56:14 +0100 Three-dimensional visualization of intracoronary thrombus during stent implantation using the second generation, Fourier domain optical coherence tomography http://www.medworm.com/index.php?rid=3328404&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F625%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328404 Mon, 01 Mar 2010 08:05:56 +0100 3328404 Corrigendum to: ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2008. The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2008 of the European Society of Cardiology. Developed in collaboration with the Heart Failure Association of the ESC (HFA) and endorsed by the European Society of Intensive Care Medicine (ESICM) [Eur Heart J 2008;29:2388-2442] http://www.medworm.com/index.php?rid=3328403&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F624%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328403 Mon, 01 Mar 2010 08:05:56 +0100 3328403 Spasm provocative test in troponin-positive patients with acute chest pain and no significant coronary artery disease: reply http://www.medworm.com/index.php?rid=3328402&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F623-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328402 Mon, 01 Mar 2010 08:05:56 +0100 3328402 Spasm provocative test in troponin-positive patients with acute chest pain and no significant coronary artery disease http://www.medworm.com/index.php?rid=3328401&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F623%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328401 Mon, 01 Mar 2010 08:05:56 +0100 3328401 Cross-sectional analysis of baseline data to identify the major determinants of carotid intima-media thickness in a European population: the IMPROVE study http://www.medworm.com/index.php?rid=3328400&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F614%3Frss%3D1 Conclusion Latitude is an important determinant of C-IMT, which is not explained by between-country differences in established VRFs. Other unknown contributory mechanisms such as heritable, nutritional, or environmental factors may be important in the genesis of this geographical gradient. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328400 Mon, 01 Mar 2010 08:05:56 +0100 3328400 Heparin-induced thrombocytopenia (HIT) as an unusual cause of acute stent thrombosis http://www.medworm.com/index.php?rid=3328399&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F613%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328399 Mon, 01 Mar 2010 08:05:56 +0100 3328399 The central arterial burden of the metabolic syndrome is similar in men and women: the SardiNIA Study http://www.medworm.com/index.php?rid=3328398&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F602%3Frss%3D1 Conclusion MetS accelerates age-associated arterial changes, even in older persons. However, not all the clusters of MetS components render the same burden on arterial structure and function. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328398 Mon, 01 Mar 2010 08:05:56 +0100 3328398 Hyponatraemia: a strong predictor of mortality in adults with congenital heart disease http://www.medworm.com/index.php?rid=3328397&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F595%3Frss%3D1 Conclusion Hyponatraemia is relatively common in ACHD. Hyponatraemia carries a three-fold higher risk of death in ACHD and is a simple, cheap but powerful marker of mortality. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328397 Mon, 01 Mar 2010 08:05:56 +0100 3328397 New insights into the relationship of left ventricular geometry and left ventricular mass with cardiac function: a population study of hypertensive subjects http://www.medworm.com/index.php?rid=3328396&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F588%3Frss%3D1 Conclusion In hypertensives, hypertrophic remodelling is independently associated with impaired LV function and increased LV filling pressure. Increasing degrees of non-hypertrophic concentric remodelling are associated with attenuated diastolic function, but augmented systolic function, possibly representing an adaptive response to pressure overload physiology. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328396 Mon, 01 Mar 2010 08:05:56 +0100 3328396 Bivalirudin vs. unfractionated heparin during percutaneous coronary interventions in patients with stable and unstable angina pectoris: 1-year results of the ISAR-REACT 3 trial http://www.medworm.com/index.php?rid=3328395&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F582%3Frss%3D1 Conclusion Bivalirudin and unfractionated heparin during PCI provide comparable outcomes at 1 year in biomarker negative patients undergoing PCI after pre-treatment with 600 mg of clopidogrel. Clinical trial registration information: URL www.clinicaltrials.gov; Unique identifier NCT00262054. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328395 Mon, 01 Mar 2010 08:05:56 +0100 3328395 Giant post-traumatic coronary aneurysm as an infrequent cause of inferior ST elevation myocardial infarction http://www.medworm.com/index.php?rid=3328394&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F581%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328394 Mon, 01 Mar 2010 08:05:56 +0100 3328394 Resolution of ST-segment depression: a new prognostic marker in ST-segment elevation myocardial infarction http://www.medworm.com/index.php?rid=3328393&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F573%3Frss%3D1 Conclusion When ST depression is present in STEMI patients undergoing primary PCI, STD-R<50% provides independent prognostic value that is incremental to STE-R. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328393 Mon, 01 Mar 2010 08:05:56 +0100 3328393 Safety and effectiveness of bivalirudin in routine care of patients undergoing percutaneous coronary intervention http://www.medworm.com/index.php?rid=3328392&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F561%3Frss%3D1 Conclusion In our non-randomized study of routine care, we observed a reduction in blood transfusions and in short-term mortality for patients treated with bivalirudin compared with heparin plus GPI. The mortality benefit was more pronounced in our study than in randomized trials. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328392 Mon, 01 Mar 2010 08:05:56 +0100 3328392 Spontaneous regression of severe traumatic tricuspid valve regurgitation http://www.medworm.com/index.php?rid=3328391&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F560%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328391 Mon, 01 Mar 2010 08:05:56 +0100 3328391 The association of admission heart rate and in-hospital cardiovascular events in patients with non-ST-segment elevation acute coronary syndromes: results from 135 164 patients in the CRUSADE quality improvement initiative http://www.medworm.com/index.php?rid=3328390&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F552%3Frss%3D1 Conclusion In contrast to patients with stable CAD, in the acute setting, the relationship between presenting HR and in-hospital cardiovascular outcomes has a ‘J-shaped’ curve (higher event rates at very low and high HRs). These associations should be considered in ACS prognostic models. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328390 Mon, 01 Mar 2010 08:05:56 +0100 3328390 Imaging and atrial fibrillation: the role of multimodality imaging in patient evaluation and management of atrial fibrillation http://www.medworm.com/index.php?rid=3328389&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F542%3Frss%3D1 Atrial fibrillation (AF) is the most common cardiac arrhythmia, and is associated with an increased risk of cardiac morbidity and mortality. In this review, the role of multimodality imaging in the evaluation and treatment of AF is discussed in two main parts. First, an overview of the initial assessment of an AF patient is provided, including the role of different imaging techniques. Conditions that are associated with AF (coronary artery disease, heart failure, valvular heart disease, and left ventricular hypertrophy), and the assessment with various imaging modalities, will be reviewed. Furthermore, left atrial size assessment and the screening for thrombus formation are addressed. Secondly, the role of imaging in the invasive treatment of AF with catheter ablation is reviewed. Issues t... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328389 Mon, 01 Mar 2010 08:05:56 +0100 3328389 Chronic stable coronary artery disease: drugs vs. revascularization http://www.medworm.com/index.php?rid=3328388&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F530%3Frss%3D1 Coronary artery disease remains the leading cause of mortality in most industrialized countries, although age-standardized mortality related to coronary artery disease (CAD) has decreased by more than 40% during the last two decades. Coronary atherosclerosis may cause angina pectoris, myocardial infarction, heart failure, arrhythmia, and sudden death. Medical management of atherosclerosis and its manifestation aims at retardation of progression of plaque formation, prevention of plaque rupture, and subsequent events and treatment of symptoms, when these occur as well as treatment of the sequelae of the disease. Revascularization by either percutaneous coronary intervention (PCI) or coronary artery bypass surgery (CABG) is performed as treatment of flow-limiting coronary stenosis to reduce ... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328388 Mon, 01 Mar 2010 08:05:56 +0100 3328388 The role of cardiac registries in evidence-based medicine http://www.medworm.com/index.php?rid=3328387&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F525%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328387 Mon, 01 Mar 2010 08:05:56 +0100 3328387 Which antithrombotic to use during PCI? http://www.medworm.com/index.php?rid=3328386&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F522%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328386 Mon, 01 Mar 2010 08:05:56 +0100 3328386 Clinical trials and registries in cardiovascular disease: competitive or complementary? http://www.medworm.com/index.php?rid=3328385&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F520%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328385 Mon, 01 Mar 2010 08:05:56 +0100 3328385 Resting heart rate and cardiovascular events: time for a new crusade? http://www.medworm.com/index.php?rid=3328384&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F517%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328384 Mon, 01 Mar 2010 08:05:56 +0100 3328384 CardioPulse Articles http://www.medworm.com/index.php?rid=3328383&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F5%2F509%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3328383 Mon, 01 Mar 2010 08:05:55 +0100 3328383 List of referees, 2009 http://www.medworm.com/index.php?rid=3270444&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F505%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270444 Sun, 14 Feb 2010 08:06:03 +0100 3270444 Cell survival: is not all about apoptosis: reply http://www.medworm.com/index.php?rid=3270443&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F503-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270443 Sun, 14 Feb 2010 08:06:03 +0100 3270443 Cell survival: is not all about apoptosis http://www.medworm.com/index.php?rid=3270442&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F503%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270442 Sun, 14 Feb 2010 08:06:03 +0100 3270442 Percutaneous assist devices vs. intra-aortic balloon pump for cardiogenic shock: evidence under construction vs. expert opinion: reply http://www.medworm.com/index.php?rid=3270441&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F502-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270441 Sun, 14 Feb 2010 08:06:03 +0100 3270441 Percutaneous assist devices vs. intra-aortic balloon pump for cardiogenic shock: evidence under construction vs. expert opinion http://www.medworm.com/index.php?rid=3270440&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F502%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270440 Sun, 14 Feb 2010 08:06:03 +0100 3270440 Both cultured and freshly isolated adipose tissue-derived stem cells enhance cardiac function after acute myocardial infarction http://www.medworm.com/index.php?rid=3270439&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F489%3Frss%3D1 Conclusion This is the first study to systematically compare the effects of fhADCs and hASCs on myocardial regeneration. Both cell types engraft into infarcted myocardium, survive, and improve myocardial function, suggesting that fhADCs, like hASCs, are a promising alternative cell source for myocardial repair after MI. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270439 Sun, 14 Feb 2010 08:06:03 +0100 3270439 Simultaneous quadruple kissing stenting of an unprotected left main coronary artery http://www.medworm.com/index.php?rid=3270438&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F488%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270438 Sun, 14 Feb 2010 08:06:03 +0100 3270438 Safety and tolerability of dalcetrapib (RO4607381/JTT-705): results from a 48-week trial http://www.medworm.com/index.php?rid=3270437&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F480%3Frss%3D1 Conclusion Dalcetrapib 900 mg administered for up to 48 weeks showed no clinically relevant changes in lymph nodes, BP, or other safety parameters. Dalcetrapib effectively increased HDL-C over 48 weeks of treatment. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270437 Sun, 14 Feb 2010 08:06:03 +0100 3270437 Impact of contrast-enhanced echocardiography on the diagnostic algorithm of acute aortic dissection http://www.medworm.com/index.php?rid=3270436&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F472%3Frss%3D1 Conclusion Contrast enhancement substantially improves TTE in the diagnosis of AD and should be considered as the initial imaging modality in the emergency setting. Contrast enhancement also has significant value for obtaining critical morphological and haemokinetic information by TOE useful for adequate patient management. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270436 Sun, 14 Feb 2010 08:06:03 +0100 3270436 Protective effect of periconceptional folic acid supplements on the risk of congenital heart defects: a registry-based case-control study in the northern Netherlands http://www.medworm.com/index.php?rid=3270435&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F464%3Frss%3D1 Conclusion Our results support the hypothesis that additional periconceptional folic acid use reduces CHD risk in infants. Use of periconceptional folic acid supplements was related to ~20% reduction in the prevalence of any CHD. Given the relatively high prevalence of CHD worldwide, our findings are important for public health. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270435 Sun, 14 Feb 2010 08:06:03 +0100 3270435 A multi-modal assessment of a multi-visceral affect of a Wegener granulomatosis http://www.medworm.com/index.php?rid=3270434&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F463%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270434 Sun, 14 Feb 2010 08:06:03 +0100 3270434 Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure http://www.medworm.com/index.php?rid=3270433&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F457%3Frss%3D1 Conclusion After ascent excessive lung fluids accumulate affecting haemoglobin oxygen saturation and, in these circumstances, CPAP is effective. Acclimatization implies spontaneous haemoglobin oxygen saturation increase and, after prolonged altitude exposure, CPAP is not associated with HbO2-sat increase suggesting a reduction in alveolar fluids. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270433 Sun, 14 Feb 2010 08:06:03 +0100 3270433 Interactive real-time mapping and catheter ablation of the cavotricuspid isthmus guided by magnetic resonance imaging in a porcine model http://www.medworm.com/index.php?rid=3270432&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F450%3Frss%3D1 Conclusion Completely non-fluoroscopic ablation guided by RTMRI using a steerable and non-ferromagnetic catheter is a promising novel technology in interventional electrophysiology. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270432 Sun, 14 Feb 2010 08:06:03 +0100 3270432 Electrocardiographic amplitudes: a new risk factor for sudden death in hypertrophic cardiomyopathy http://www.medworm.com/index.php?rid=3270431&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F439%3Frss%3D1 Conclusion Twelve-lead ECG is a powerful instrument for risk-stratification in HCM. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270431 Sun, 14 Feb 2010 08:06:03 +0100 3270431 Chronic nitrate therapy is associated with different presentation and evolution of acute coronary syndromes: insights from 52 693 patients in the Global Registry of Acute Coronary Events http://www.medworm.com/index.php?rid=3270430&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F430%3Frss%3D1 Conclusion In this large multinational registry, chronic nitrate use was associated with a shift away from STEMI in favour of NSTE-ACS and with less release of markers of cardiac necrosis. These findings suggest that in nitrate users acute coronary events may develop to a smaller extent. Randomized, placebo-controlled trials are warranted to establish whether nitrate therapy may pharmacologically precondition the heart toward ischaemic episodes. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270430 Sun, 14 Feb 2010 08:06:03 +0100 3270430 Salivary cortisol responses to mental stress are associated with coronary artery calcification in healthy men and women http://www.medworm.com/index.php?rid=3270429&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F424%3Frss%3D1 Conclusion In healthy, older participants without history or objective signs of CHD, heightened cortisol reactivity is associated with a greater extent of CAC. These data support the notion that heightened hypothalamic pituitary adrenal activity is a risk factor for CHD. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270429 Sun, 14 Feb 2010 08:06:03 +0100 3270429 Risk stratification of patients with aortic stenosis http://www.medworm.com/index.php?rid=3270428&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F416%3Frss%3D1 Aortic stenosis (AS) is now the most common indication for valve replacement in Europe and North America, with an ever increasing disease prevalence due to the ageing population (Iung B, Baron G, Butchart EG, Delahaye F, Gohlke-Bärwolf C, Levang AW, Tornos P, Vanoverschelde JL, Vermeer F, Boersma E, Ravaud P, Vahanian A. A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on valvular heart disease. Eur Heart J 2003; 24:1231–1243). The recent introduction of transcatheter aortic valve implantation has renewed interest in the optimal approach to patient management. Decision making in valvular heart disease necessitates a careful evaluation of the risk-to-benefit ratio, considering both the results of intervention and the severity-adjusted ... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270428 Sun, 14 Feb 2010 08:06:02 +0100 3270428 Three-dimensional reconstruction imaging of the human foetal heart in the first trimester http://www.medworm.com/index.php?rid=3270427&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F415%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270427 Sun, 14 Feb 2010 08:06:02 +0100 3270427 Expert review document on methodology, terminology, and clinical applications of optical coherence tomography: physical principles, methodology of image acquisition, and clinical application for assessment of coronary arteries and atherosclerosis http://www.medworm.com/index.php?rid=3270426&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F401%3Frss%3D1 Optical coherence tomography (OCT) is a novel intravascular imaging modality, based on infrared light emission, that enables a high resolution arterial wall imaging, in the range of 10–20 microns. This feature of OCT allows the visualization of specific components of the atherosclerotic plaques. The aim of the present Expert Review Document is to address the methodology, terminology and clinical applications of OCT for qualitative and quantitative assessment of coronary arteries and atherosclerosis. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270426 Sun, 14 Feb 2010 08:06:02 +0100 3270426 Severe ventricular arrhythmias in a patient with cardiac sarcoidosis: insights from MRI and PET imaging and importance of early corticosteroid therapy http://www.medworm.com/index.php?rid=3270425&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F400%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270425 Sun, 14 Feb 2010 08:06:02 +0100 3270425 A better echocardiographic view to aortic dissection http://www.medworm.com/index.php?rid=3270424&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F398%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270424 Sun, 14 Feb 2010 08:06:02 +0100 3270424 Cultured and freshly isolated adipose tissue-derived cells: fat years for cardiac stem cell therapy http://www.medworm.com/index.php?rid=3270423&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F394%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270423 Sun, 14 Feb 2010 08:06:02 +0100 3270423 Mulling over the odds of CETP inhibition http://www.medworm.com/index.php?rid=3270422&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F390%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270422 Sun, 14 Feb 2010 08:06:02 +0100 3270422 CardioPulse Articles http://www.medworm.com/index.php?rid=3270421&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F4%2F383%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3270421 Sun, 14 Feb 2010 08:06:02 +0100 3270421 Right ventricular hypertrophy and scarring in mutation positive hypertrophic cardiomyopathy http://www.medworm.com/index.php?rid=3225679&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F381%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225679 Mon, 01 Feb 2010 08:06:54 +0100 3225679 Cardiac fibroelastoma causing angina http://www.medworm.com/index.php?rid=3225678&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F380%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225678 Mon, 01 Feb 2010 08:06:54 +0100 3225678 Corrigendum to: 'Recommendations for interpretation of 12-lead electrocardiogram in the athlete' [Eur Heart J 2010;31:243-259] http://www.medworm.com/index.php?rid=3225677&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F379-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225677 Mon, 01 Feb 2010 08:06:54 +0100 3225677 Corrigendum to: 'Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery: The Task Force for Preoperative Cardiac Risk Assessment and Perioperative Cardiac Management in Non-cardiac Surgery of the European Society of Cardiology (ESC) and endorsed by the European Society of Anaesthesiology (ESA)' [Eur Heart J 2009;30:2769-2812] http://www.medworm.com/index.php?rid=3225676&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F379%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225676 Mon, 01 Feb 2010 08:06:53 +0100 3225676 The importance of witnesses to maximize survival from out-of-hospital cardiac arrest: reply http://www.medworm.com/index.php?rid=3225675&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F378-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225675 Mon, 01 Feb 2010 08:06:53 +0100 3225675 The importance of witnesses to maximize survival from out-of-hospital cardiac arrest http://www.medworm.com/index.php?rid=3225674&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F378%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225674 Mon, 01 Feb 2010 08:06:53 +0100 3225674 The role of oestrogen in the pathophysiologic process of the Tako-Tsubo cardiomyopathy: reply http://www.medworm.com/index.php?rid=3225673&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F377-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225673 Mon, 01 Feb 2010 08:06:53 +0100 3225673 The role of oestrogen in the pathophysiologic process of the Tako-Tsubo cardiomyopathy http://www.medworm.com/index.php?rid=3225672&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F377%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225672 Mon, 01 Feb 2010 08:06:53 +0100 3225672 Monocyte heterogeneity in obesity and subclinical atherosclerosis http://www.medworm.com/index.php?rid=3225671&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F369%3Frss%3D1 Conclusion Our results reveal a significant univariate association between CD16+ monocytes and both obesity and subclinical atherosclerosis in low-risk individuals. They are in line with recent observations that CD16+ monocytes show high endothelial affinity and a potent capacity to invade vascular lesions and to transform into pro-inflammatory cytokine producing macrophages. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225671 Mon, 01 Feb 2010 08:06:53 +0100 3225671 Protecting the brain from gaseous and solid micro-emboli during coronary artery bypass grafting: a randomized controlled trial http://www.medworm.com/index.php?rid=3225670&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F360%3Frss%3D1 Conclusion Gaseous micro-embolization contributes to neuropsychological decline, which is measurable 3 months post-operatively. No filter device could protect the brain during CABG completely. However, the use of the DBT tends to improve the cognitive outcome after CABG. Gas filters are recommendable for neuroprotection during cardiac surgery. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225670 Mon, 01 Feb 2010 08:06:53 +0100 3225670 Pregnancy-associated plasma protein-A is an independent short-time predictor of mortality in patients on maintenance haemodialysis http://www.medworm.com/index.php?rid=3225669&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F354%3Frss%3D1 Conclusion PAPP-A is a novel and independent short-time predictor of mortality in a maintenance HD population. The pathogenetic relevance of PAPP-A, particularly in the development of cardiovascular disease, remains to be further elucidated. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225669 Mon, 01 Feb 2010 08:06:53 +0100 3225669 Aortic remodelling in Fabry disease http://www.medworm.com/index.php?rid=3225668&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F347%3Frss%3D1 Conclusion Fabry disease should be considered as a cardiovascular disease that affects the heart and arterial vasculature, including the thoracic aorta. Thus, patients with FD should be closely monitored for the presence, and possible progression and complications of aortic dilation. Clinical Trial Registration: Protocol 101/01. Ethics committee, Faculty of Medicine, Lausanne. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225668 Mon, 01 Feb 2010 08:06:53 +0100 3225668 Coronary computed tomography angiography with a consistent dose below 1 mSv using prospectively electrocardiogram-triggered high-pitch spiral acquisition http://www.medworm.com/index.php?rid=3225667&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F340%3Frss%3D1 Conclusion In non-obese patients with a low and stable heart rate, prospectively ECG-triggered high-pitch spiral coronary CTA provides excellent image quality at a consistent dose below 1.0 mSv. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225667 Mon, 01 Feb 2010 08:06:53 +0100 3225667 Mode of onset of ventricular fibrillation in patients with early repolarization pattern vs. Brugada syndrome http://www.medworm.com/index.php?rid=3225666&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F330%3Frss%3D1 Conclusion Our study provides additional evidence in support of the hypothesis that ER pattern in the ECG is not always benign. Transient augmentation of global J waves may be indicative of a highly arrhythmogenic substrate heralding multiple episodes of VF in patients with ER pattern. Ventricular tachycardia/VF initiation is more commonly associated with an SLS sequence, and PVCs display a shorter coupling interval in patients with ER pattern compared with those with BrS. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225666 Mon, 01 Feb 2010 08:06:53 +0100 3225666 Cocaine-related sudden death: a prospective investigation in south-west Spain http://www.medworm.com/index.php?rid=3225665&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F318%3Frss%3D1 Conclusion Systematic toxicology investigation indicates that 3.1% of SDs are COC-related and are mainly due to cardio-cerebrovascular causes. Left ventricular hypertrophy, small vessel disease, and premature coronary artery atherosclerosis, with or without lumen thrombosis, are frequent findings that may account for myocardial ischaemia at risk of cardiac arrest in COC addicts. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225665 Mon, 01 Feb 2010 08:06:53 +0100 3225665 The answer lies in the bubbles: a patient with superior sinus venosus defect, persistent left superior vena cava, and absent innominate vein http://www.medworm.com/index.php?rid=3225664&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F317%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225664 Mon, 01 Feb 2010 08:06:53 +0100 3225664 Atrial fibrillation and long-term prognosis in patients hospitalized for heart failure: results from heart failure survey in Israel (HFSIS) http://www.medworm.com/index.php?rid=3225663&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F309%3Frss%3D1 Conclusion AF was present in a third of hospitalized HF patients, and identified a population with increased mortality risk, largely due to co-morbidities. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225663 Mon, 01 Feb 2010 08:06:53 +0100 3225663 Prognostic implications of left ventricular dyssynchrony early after non-ST elevation myocardial infarction without congestive heart failure http://www.medworm.com/index.php?rid=3225662&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F298%3Frss%3D1 Conclusion After NSTEMI, proximal LCx stenosis and impaired LV function independently predicted LV dyssynchrony. The composite dyssynchrony score had prognostic value and identified patients with persistently dilated and impaired LV on follow-up. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225662 Mon, 01 Feb 2010 08:06:53 +0100 3225662 C-reactive protein improves risk prediction in patients with acute coronary syndromes http://www.medworm.com/index.php?rid=3225661&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F290%3Frss%3D1 Conclusion Elevated C-reactive protein level is a modest but independent predictive factor of 30-day mortality in ACS patients, even after adjustment for co-morbidities, haemodynamic conditions, and treatment. Combined with the GRACE risk score, C-reactive protein information improves risk classification. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225661 Mon, 01 Feb 2010 08:06:53 +0100 3225661 Paradoxical low flow and/or low gradient severe aortic stenosis despite preserved left ventricular ejection fraction: implications for diagnosis and treatment http://www.medworm.com/index.php?rid=3225660&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F281%3Frss%3D1 Paradoxical low flow, low gradient, severe aortic stenosis (AS) despite preserved ejection fraction is a recently described clinical entity whereby patients with severe AS on the basis of aortic valve area have a lower than expected gradient in relation to generally accepted values. This mode of presentation of severe AS is relatively frequent (up to 35% of cases) and such patients have a cluster of findings, indicating that they are at a more advanced stage of their disease and have a poorer prognosis if treated medically rather than surgically. Yet, a majority of these patients do not undergo surgery likely due to the fact that the reduced gradient is conducive to an underestimation of the severity of the disease and/or of symptoms. The purpose of this article is to review and further an... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225660 Mon, 01 Feb 2010 08:06:53 +0100 3225660 Stay off-pump and do not touch the aorta! http://www.medworm.com/index.php?rid=3225659&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F278%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225659 Mon, 01 Feb 2010 08:06:53 +0100 3225659 Myocarditis in a juvenile patient with influenza A virus infection http://www.medworm.com/index.php?rid=3225658&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F277%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225658 Mon, 01 Feb 2010 08:06:53 +0100 3225658 C-reactive protein improves risk prediction in patients with acute coronary syndrome, or does it? http://www.medworm.com/index.php?rid=3225657&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F274%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225657 Mon, 01 Feb 2010 08:06:53 +0100 3225657 Sudden death in cocaine abusers http://www.medworm.com/index.php?rid=3225656&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F271%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225656 Mon, 01 Feb 2010 08:06:53 +0100 3225656 CardioPulse Articles http://www.medworm.com/index.php?rid=3225655&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F3%2F263%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3225655 Mon, 01 Feb 2010 08:06:52 +0100 3225655 Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study: reply http://www.medworm.com/index.php?rid=3168665&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F262%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168665 Thu, 14 Jan 2010 08:06:41 +0100 3168665 Effects of valsartan on morbidity and mortality in uncontrolled hypertensive patients with high cardiovascular risks: KYOTO HEART Study http://www.medworm.com/index.php?rid=3168664&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F261%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168664 Thu, 14 Jan 2010 08:06:41 +0100 3168664 Late stent malapposition: innocent phenomenon or major risk marker? reply http://www.medworm.com/index.php?rid=3168663&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F260-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168663 Thu, 14 Jan 2010 08:06:41 +0100 3168663 Late stent malapposition: innocent phenomenon or major risk marker? http://www.medworm.com/index.php?rid=3168662&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F260%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168662 Thu, 14 Jan 2010 08:06:41 +0100 3168662 Recommendations for interpretation of 12-lead electrocardiogram in the athlete http://www.medworm.com/index.php?rid=3168661&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F243%3Frss%3D1 Cardiovascular remodelling in the conditioned athlete is frequently associated with physiological ECG changes. Abnormalities, however, may be detected which represent expression of an underlying heart disease that puts the athlete at risk of arrhythmic cardiac arrest during sports. It is mandatory that ECG changes resulting from intensive physical training are distinguished from abnormalities which reflect a potential cardiac pathology. The present article represents the consensus statement of an international panel of cardiologists and sports medical physicians with expertise in the fields of electrocardiography, imaging, inherited cardiovascular disease, cardiovascular pathology, and management of young competitive athletes. The document provides cardiologists and sports medical physicia... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168661 Thu, 14 Jan 2010 08:06:41 +0100 3168661 Rapamycin promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents http://www.medworm.com/index.php?rid=3168660&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F236%3Frss%3D1 Conclusion Rapamycin increases TF activity and promotes arterial thrombosis in vivo at concentrations relevant in patients undergoing DES implantation; this effect may increase the thrombogenicity of DES. Since everolimus and zotarolimus augment endothelial TF expression and activity in vitro in a similar manner as rapamycin, these findings may also be relevant for second generation DES. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168660 Thu, 14 Jan 2010 08:06:41 +0100 3168660 Correlation of inhibition of platelet aggregation after clopidogrel with post discharge bleeding events: assessment by different bleeding classifications http://www.medworm.com/index.php?rid=3168659&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F227%3Frss%3D1 Conclusion Chronic oral combination antiplatelet regimens are associated with a very high (56.5–60.7%) prevalence of superficial bleeding episodes, which are grossly underestimated in trials and registries. The role of such frequent mild complications for the overall benefit of antiplatelet therapy is entirely unknown, as is their effect on compliance. Although IPA is well suited for defining the risk of minor complications, prediction of more severe bleeding events may be challenging. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168659 Thu, 14 Jan 2010 08:06:41 +0100 3168659 Obesity paradox in a cohort of 4880 consecutive patients undergoing percutaneous coronary intervention http://www.medworm.com/index.php?rid=3168658&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F222%3Frss%3D1 Conclusion Among patients undergoing percutaneous intervention for coronary artery disease, increased BMI was associated with improved 5 year survival. Among those with established coronary disease, the adverse effects of excess adipose tissue may be offset by beneficial vasoactive properties. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168658 Thu, 14 Jan 2010 08:06:41 +0100 3168658 Predictors of sudden cardiac death change with time after myocardial infarction: results from the VALIANT trial http://www.medworm.com/index.php?rid=3168657&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F211%3Frss%3D1 Conclusion Predictors of SCD change with time after MI. Future studies of risk stratification for SCD should account for changes in these factors with time after MI. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168657 Thu, 14 Jan 2010 08:06:41 +0100 3168657 Prevalence and risk factors related to infections of cardiac resynchronization therapy devices http://www.medworm.com/index.php?rid=3168656&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F203%3Frss%3D1 Conclusion This study found that the prevalence of CRT DRI is close to 4.3% at 2.6 years (1.7% per year incidence). Four independent predictive factors of infections were identified including re-intervention, procedure time, dialysis, and primo CRT-ICD implantation. These parameters should be part of the risk–benefit evaluation in patients selected for CRT implantation. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168656 Thu, 14 Jan 2010 08:06:41 +0100 3168656 Do systemic risk factors impact invasive findings from virtual histology? Insights from the international virtual histology registry http://www.medworm.com/index.php?rid=3168655&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F196%3Frss%3D1 Conclusion Radiofrequency-IVUS detects marked differences in coronary plaque composition related to the risk factor profile with particular focus on lipid levels. Greater amounts of NC were associated with diabetes, hypertension, MI, and low HDL-C. The effects of treatment of changes related to plaque composition are underway. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168655 Thu, 14 Jan 2010 08:06:41 +0100 3168655 Prognostic value of peak and post-exercise treadmill exercise echocardiography in patients with known or suspected coronary artery disease http://www.medworm.com/index.php?rid=3168654&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F187%3Frss%3D1 Conclusion Peak treadmill EE provides significant incremental information over post-EE for predicting outcome in patients with known or suspected CAD. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168654 Thu, 14 Jan 2010 08:06:41 +0100 3168654 Safety and efficacy of drug-eluting vs. bare metal stents in patients with diabetes mellitus: long-term follow-up in the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) http://www.medworm.com/index.php?rid=3168653&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F177%3Frss%3D1 Conclusion This real-life registry study shows that restenosis was halved by DES in diabetic patients with stable or unstable coronary disease, with similar risk of death or MI up to 4 years compared with BMS. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168653 Thu, 14 Jan 2010 08:06:40 +0100 3168653 An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study http://www.medworm.com/index.php?rid=3168652&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F165%3Frss%3D1 Conclusion Strut coverage at an average follow-up of 9 months appears to be more complete in patients allocated to BESs when compared with SESs. The impact of this difference on clinical outcome and, in particular, on the risk of late stent thrombosis is yet to be determined. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168652 Thu, 14 Jan 2010 08:06:40 +0100 3168652 Left aortic sinus to right atrial tunnel http://www.medworm.com/index.php?rid=3168651&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F164%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168651 Thu, 14 Jan 2010 08:06:40 +0100 3168651 Cholesteryl ester transfer protein: at the heart of the action of lipid-modulating therapy with statins, fibrates, niacin, and cholesteryl ester transfer protein inhibitors http://www.medworm.com/index.php?rid=3168650&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F149%3Frss%3D1 Subnormal plasma levels of high-density lipoprotein cholesterol (HDL-C) constitute a major cardiovascular risk factor; raising low HDL-C levels may therefore reduce the residual cardiovascular risk that frequently presents in dyslipidaemic subjects despite statin therapy. Cholesteryl ester transfer protein (CETP), a key modulator not only of the intravascular metabolism of HDL and apolipoprotein (apo) A-I but also of triglyceride (TG)-rich particles and low-density lipoprotein (LDL), mediates the transfer of cholesteryl esters from HDL to pro-atherogenic apoB-lipoproteins, with heterotransfer of TG mainly from very low-density lipoprotein to HDL. Cholesteryl ester transfer protein activity is elevated in the dyslipidaemias of metabolic disease involving insulin resistance and moderate to m... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168650 Thu, 14 Jan 2010 08:06:40 +0100 3168650 The 'left' ventricle during pulsatile mechanical assistance: reliability of cardiac output monitoring with an uncalibrated pulse contour method http://www.medworm.com/index.php?rid=3168649&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F148%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168649 Thu, 14 Jan 2010 08:06:40 +0100 3168649 The obesity paradox: weighing the benefit http://www.medworm.com/index.php?rid=3168648&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F146%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168648 Thu, 14 Jan 2010 08:06:40 +0100 3168648 Aorto-left ventricular tunnel causing severe aortic regurgitation in adult man http://www.medworm.com/index.php?rid=3168647&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F145%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168647 Thu, 14 Jan 2010 08:06:40 +0100 3168647 Which stent for diabetic patients: the glass half-full or half-empty? http://www.medworm.com/index.php?rid=3168646&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F143%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168646 Thu, 14 Jan 2010 08:06:40 +0100 3168646 Late device thrombosis after atrial septal defect closure http://www.medworm.com/index.php?rid=3168645&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F142%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168645 Thu, 14 Jan 2010 08:06:40 +0100 3168645 Unravelling the endovascular microenvironment by optical coherence tomography http://www.medworm.com/index.php?rid=3168644&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F139%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168644 Thu, 14 Jan 2010 08:06:40 +0100 3168644 CardioPulse Articles http://www.medworm.com/index.php?rid=3168643&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F2%2F131%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3168643 Thu, 14 Jan 2010 08:06:40 +0100 3168643 Prognostic value of circulating chromogranin A levels in acute coronary syndrome: reply http://www.medworm.com/index.php?rid=3134375&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F128-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134375 Fri, 01 Jan 2010 08:06:39 +0100 3134375 Prognostic value of circulating chromogranin A levels in acute coronary syndrome http://www.medworm.com/index.php?rid=3134374&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F128%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134374 Fri, 01 Jan 2010 08:06:39 +0100 3134374 Unusual findings in hypertension screening: aortic coarctation, double orifice mitral valve, and patent ductus arteriosus http://www.medworm.com/index.php?rid=3134373&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F127%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134373 Fri, 01 Jan 2010 08:06:39 +0100 3134373 N-terminal pro-B-type natriuretic peptide is an independent predictor of cardiovascular morbidity and mortality in the general population http://www.medworm.com/index.php?rid=3134372&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F120%3Frss%3D1 Conclusion In this large community-based cohort, plasma NT-proBNP was a strong predictor of death and a wide range of CV events. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134372 Fri, 01 Jan 2010 08:06:39 +0100 3134372 Long- but not short-term multifactorial intervention with focus on exercise training improves coronary endothelial dysfunction in diabetes mellitus type 2 and coronary artery disease http://www.medworm.com/index.php?rid=3134371&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F112%3Frss%3D1 Conclusion This is the first study to demonstrate improvement in coronary endothelial function by a multifactorial intervention which focused on exercise training in patients with T2DM. This coincided with improved markers of hyperglycaemia, insulin sensitivity, and inflammation both in serum and skeletal muscle biopsies. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134371 Fri, 01 Jan 2010 08:06:39 +0100 3134371 Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction http://www.medworm.com/index.php?rid=3134370&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F100%3Frss%3D1 Conclusion Our data show that the mechanisms of myocardial insulin resistance are different between NIDDM and LVD. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134370 Fri, 01 Jan 2010 08:06:39 +0100 3134370 Incidence and predictors of silent myocardial infarction in type 2 diabetes and the effect of fenofibrate: an analysis from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study http://www.medworm.com/index.php?rid=3134369&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F92%3Frss%3D1 Conclusion Silent and clinical MI have similar risk factors and increase the risk of future CVD events. Fenofibrate reduces the risk of a first MI and substantially reduces the risk of further clinical CVD events after silent MI, supporting its use in type 2 diabetes. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134369 Fri, 01 Jan 2010 08:06:39 +0100 3134369 Orthostatic hypotension predicts all-cause mortality and coronary events in middle-aged individuals (The Malmo Preventive Project) http://www.medworm.com/index.php?rid=3134368&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F85%3Frss%3D1 Conclusion Orthostatic hypotension can be detected in ~6% of middle-aged individuals and is often associated with such comorbidities as hypertension or diabetes. Presence of OH increases mortality and CE risk, independently of traditional risk factors. Although both impaired systolic and diastolic responses predict adverse events, the diastolic impairment shows stronger association with coronary disease. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134368 Fri, 01 Jan 2010 08:06:39 +0100 3134368 Hip fractures and heart failure: findings from the Cardiovascular Health Study http://www.medworm.com/index.php?rid=3134367&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F77%3Frss%3D1 Conclusion Persons with heart failure are at high risk for hip fractures. However, much of the association between hip fractures and heart failure is explained by shared risk factors. Hip fractures are a substantial contributor to mortality in men and women with heart failure. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134367 Fri, 01 Jan 2010 08:06:38 +0100 3134367 An indirect shot to the heart http://www.medworm.com/index.php?rid=3134366&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F76%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134366 Fri, 01 Jan 2010 08:06:38 +0100 3134366 Evidence for a role of sphingosine-1 phosphate in cardiovascular remodelling in Fabry disease http://www.medworm.com/index.php?rid=3134365&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F67%3Frss%3D1 Conclusion Sphingosine-1 phosphate participates in cardiovascular remodelling in Fabry disease. Our findings have implications for the treatment of cardiovascular involvement in Fabry disease. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134365 Fri, 01 Jan 2010 08:06:38 +0100 3134365 Early but not late stent thrombosis is influenced by residual platelet aggregation in patients undergoing coronary interventions http://www.medworm.com/index.php?rid=3134364&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F59%3Frss%3D1 Conclusion Post-interventional RPA is associated with the occurrence of early ST in patients treated with either BMS or DES; however, there is no predictive value of RPA for the incidence of 3-month LAT, suggesting the involvement of other possible mechanisms like discontinuation of antiplatelet therapy. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134364 Fri, 01 Jan 2010 08:06:38 +0100 3134364 Collaboration between cardiac computed tomography and echocardiography in complex anomalies http://www.medworm.com/index.php?rid=3134363&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F58%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134363 Fri, 01 Jan 2010 08:06:38 +0100 3134363 Relationship between baseline haemoglobin and major bleeding complications in acute coronary syndromes http://www.medworm.com/index.php?rid=3134362&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F50%3Frss%3D1 Conclusion A low baseline haemoglobin level is an independent predictor of the risk of major bleeding in ACS as well as of the risk of death and death and MI. Among other predictors of bleeding risk, baseline haemoglobin should be taken into account in patients presenting with ACS. Clinical trial registration: ClinicalTrials.gov number, NCT00139815. http://clinicaltrials.gov/ct2/show/NCT00139815?term=NCT00139815&rank=1. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134362 Fri, 01 Jan 2010 08:06:38 +0100 3134362 Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials http://www.medworm.com/index.php?rid=3134361&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F35%3Frss%3D1 Conclusion Tirofiban administration reduces mortality, the composite of death or MI and increases minor bleedings when compared with placebo. An early ischaemic hazard disfavouring tirofiban was noted when compared with abciximab in studies based on 10 but not 25 µg/kg tirofiban bolus regimen. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134361 Fri, 01 Jan 2010 08:06:38 +0100 3134361 Fish intake and acute coronary syndrome http://www.medworm.com/index.php?rid=3134360&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F29%3Frss%3D1 Conclusion In conclusion, a modest intake of fatty fish was associated with a lower risk of ACS in middle-aged men, whereas no consistent associations were observed among women. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134360 Fri, 01 Jan 2010 08:06:38 +0100 3134360 European Society of Cardiology National Cardiovascular Journals: the 'Editors' Network' http://www.medworm.com/index.php?rid=3134359&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F26%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134359 Fri, 01 Jan 2010 08:06:38 +0100 3134359 Platelet thrombin receptor antagonism and atherothrombosis http://www.medworm.com/index.php?rid=3134358&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F17%3Frss%3D1 Clinical manifestations of atherothrombotic disease, such as acute coronary syndromes, cerebrovascular events, and peripheral arterial disease, are major causes of mortality and morbidity worldwide. Platelet activation and aggregation are ultimately responsible for the progression and clinical presentations of atherothrombotic disease. The current standard of care, dual oral antiplatelet therapy with aspirin and the P2Y12 adenosine diphosphate (ADP) receptor inhibitor clopidogrel, has been shown to improve outcomes in patients with atherothrombotic disease. However, aspirin and P2Y12 inhibitors target the thromboxane A2 and the ADP P2Y12 platelet activation pathways and minimally affect other pathways, while agonists such as thrombin, considered to be the most potent platelet activator, co... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134358 Fri, 01 Jan 2010 08:06:38 +0100 3134358 Potential usefulness of fish oil in the primary prevention of acute coronary syndrome http://www.medworm.com/index.php?rid=3134357&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F15%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134357 Fri, 01 Jan 2010 08:06:38 +0100 3134357 Acute and chronic renal artery stenosis http://www.medworm.com/index.php?rid=3134356&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F14%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134356 Fri, 01 Jan 2010 08:06:38 +0100 3134356 Orthostatic hypotension and cardiovascular risk: defining the epidemiological and prognostic relevance http://www.medworm.com/index.php?rid=3134355&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F12%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134355 Fri, 01 Jan 2010 08:06:38 +0100 3134355 A new pathway? Failure, fragility and fractures http://www.medworm.com/index.php?rid=3134354&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F9%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134354 Fri, 01 Jan 2010 08:06:38 +0100 3134354 CardioPulse Articles http://www.medworm.com/index.php?rid=3134353&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F31%2F1%2F1%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3134353 Fri, 01 Jan 2010 08:06:38 +0100 3134353 Routine stent implantation vs. percutaneous transluminal angioplasty in femoropopliteal artery disease: a meta-analysis of randomized controlled trials: reply http://www.medworm.com/index.php?rid=3083527&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3083-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083527 Mon, 14 Dec 2009 08:06:55 +0100 3083527 Routine stent implantation vs. percutaneous transluminal angioplasty in femoropopliteal artery disease: a meta-analysis of randomized controlled trials http://www.medworm.com/index.php?rid=3083526&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3083%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083526 Mon, 14 Dec 2009 08:06:55 +0100 3083526 Bariatric surgery and inflammatory markers: the jury is still out: reply http://www.medworm.com/index.php?rid=3083525&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3082-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083525 Mon, 14 Dec 2009 08:06:55 +0100 3083525 Bariatric surgery and inflammatory markers: the jury is still out http://www.medworm.com/index.php?rid=3083524&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3082%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083524 Mon, 14 Dec 2009 08:06:55 +0100 3083524 Systemic telomere length and preclinical atherosclerosis: the Asklepios Study http://www.medworm.com/index.php?rid=3083523&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3074%3Frss%3D1 Conclusion Since systemic TL is not a substantial underlying determinant of preclinical atherosclerosis, the association between CVD and TL cannot be explained by the fact that subjects with shorter inherited TL are predisposed to atherosclerosis. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083523 Mon, 14 Dec 2009 08:06:55 +0100 3083523 Mitral valve re-repair: correlating real-time three-dimensional intra-operative transoesophageal echocardiography and surgical findings http://www.medworm.com/index.php?rid=3083522&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3073%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083522 Mon, 14 Dec 2009 08:06:55 +0100 3083522 Improvement in coronary endothelial function is independently associated with a slowed progression of coronary artery calcification in type 2 diabetes mellitus http://www.medworm.com/index.php?rid=3083521&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3064%3Frss%3D1 Conclusion In DM, glucose-lowering treatment may beneficially affect structure and function of the vascular wall, whereas the observed improvement in endothelium-related coronary artery function may also mediate direct preventive effects on the progression of CAC. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083521 Mon, 14 Dec 2009 08:06:55 +0100 3083521 Cardiac magnetic resonance characterization of atrial pseudo-mass in Erdheim-Chester disease http://www.medworm.com/index.php?rid=3083520&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3063%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083520 Mon, 14 Dec 2009 08:06:55 +0100 3083520 Does abdominal obesity have a similar impact on cardiovascular disease and diabetes? A study of 91 246 ambulant patients in 27 European Countries http://www.medworm.com/index.php?rid=3083519&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3055%3Frss%3D1 Conclusion Abdominal obesity impacted similarly on the frequency of diabetes across Europe, despite regional differences in cardiovascular risk factors and CVD rates. Increasing abdominal obesity may offset future declines in CVD, even where CVD rates are lower. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083519 Mon, 14 Dec 2009 08:06:55 +0100 3083519 Decreased platelet nitric oxide contributes to increased circulating monocyte-platelet aggregates in hypertension http://www.medworm.com/index.php?rid=3083518&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3048%3Frss%3D1 Conclusion Platelet NO production and responsiveness are suppressed with raised BP, and this may contribute to the increase in platelet P-selectin and hence in circulating MPA in hypertension. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083518 Mon, 14 Dec 2009 08:06:55 +0100 3083518 Strain analysis in patients with severe aortic stenosis and preserved left ventricular ejection fraction undergoing surgical valve replacement http://www.medworm.com/index.php?rid=3083517&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3037%3Frss%3D1 Conclusion In severe AS patients, impaired LV S-and-SR existed although LVEF was preserved. After AVR, a significant S-and-SR improvement in all the three directions was observed. These subtle changes in LV contractility can be detected by 2D-STI. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083517 Mon, 14 Dec 2009 08:06:55 +0100 3083517 Blunted frequency-dependent upregulation of cardiac output is related to impaired relaxation in diastolic heart failure http://www.medworm.com/index.php?rid=3083516&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3027%3Frss%3D1 Conclusion In HFNEF, frequency-dependent upregulation of cardiac output is blunted. This results from progressive volume unloading of the left ventricle due to limited relaxation reserve in combination with increased LV passive stiffness, despite preserved force–frequency relation. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083516 Mon, 14 Dec 2009 08:06:55 +0100 3083516 Effects of low-dose oral enoximone administration on mortality, morbidity, and exercise capacity in patients with advanced heart failure: the randomized, double-blind, placebo-controlled, parallel group ESSENTIAL trials http://www.medworm.com/index.php?rid=3083515&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3015%3Frss%3D1 Conclusion Although low-dose enoximone appears to be safe in patients with advanced HF, major clinical outcomes are not improved. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083515 Mon, 14 Dec 2009 08:06:55 +0100 3083515 Abnormal coronary reserve and left ventricular wall motion during cold pressor test in patients with previous left ventricular ballooning syndrome http://www.medworm.com/index.php?rid=3083514&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3007%3Frss%3D1 Conclusion Cold pressor test induced LV wall motion abnormalities unmatched to regional coronary flow reduction in LVBS patients only. The reduced coronary reserve in response to CPT suggests microvascular dysfunction in LVBS patients. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083514 Mon, 14 Dec 2009 08:06:55 +0100 3083514 Exercise haemodynamic variables rather than ventilatory efficiency indexes contribute to risk assessment in chronic heart failure patients treated with carvedilol http://www.medworm.com/index.php?rid=3083513&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F3000%3Frss%3D1 Conclusion All traditional CPET risk parameters were informative in beta-blockers CHF patients, but peak SBP, peak CP, and EOV were the most predictive. In this low-risk population, EOV, although underrepresented, considerably enhanced risk stratification, although other ventilatory efficiency indexes provided less impressive predictive content. In large majority of non-EOV patients, peak SBP improved risk evaluation beyond other CPET parameters. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083513 Mon, 14 Dec 2009 08:06:55 +0100 3083513 Left bundle branch block causes relative but not absolute septal underperfusion during exercise http://www.medworm.com/index.php?rid=3083512&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2993%3Frss%3D1 Conclusion The apparent septal perfusion defect in LBBB is mainly due to a relative lateral hyperperfusion rather than to an absolute septal flow decrease. This pattern seems to be reversibly inducible by right ventricular pacing, suggesting a functional rather than a structural alteration. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083512 Mon, 14 Dec 2009 08:06:55 +0100 3083512 New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance http://www.medworm.com/index.php?rid=3083511&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2985%3Frss%3D1 Conclusion This study, for the first time, reveals the prevalence of latent BrS in patients with new-onset lone AF, which may precede VT/VF. Persistence of type 1 and ventricular tachyarrhythmias inducibility represents a marker of electrical instability leading to sudden death. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083511 Mon, 14 Dec 2009 08:06:55 +0100 3083511 Intracoronary bone marrow cell transfer after myocardial infarction: 5-year follow-up from the randomized-controlled BOOST trial http://www.medworm.com/index.php?rid=3083510&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2978%3Frss%3D1 Conclusion A single intracoronary application of BMCs does not promote a sustained improvement of LVEF in STEMI patients with relatively preserved systolic function. It is conceivable that a subgroup of patients with more transmural infarcts may derive a sustained benefit from BMC therapy. However, this needs to be tested prospectively in a randomized trial. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083510 Mon, 14 Dec 2009 08:06:55 +0100 3083510 Early and comprehensive management of atrial fibrillation: executive summary of the proceedings from the 2nd AFNET-EHRA consensus conference 'research perspectives in AF' http://www.medworm.com/index.php?rid=3083509&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2969%3Frss%3D1 Atrial fibrillation (AF) causes important mortality and morbidity on a population-level. So far, we do not have the means to prevent AF or AF-related complications adequately. Therefore, over 70 experts on atrial fibrillation convened for the 2nd AFNET/EHRA consensus conference to suggest directions for research to improve management of AF patients (Appendix 1). The group defined three main areas in need for research in AF: 1. better understanding of the mechanisms of AF; 2. Improving rhythm control monitoring and management; and 3. comprehensive cardiovascular risk management in AF patients. The group put forward the hypothesis that successful therapy of AF and its associated complications will require comprehensive therapy. This applies e.g. to the "old" debate of "rate versus rhythm con... European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083509 Mon, 14 Dec 2009 08:06:55 +0100 3083509 Sixty-four-slice computed tomography for the detection of multiple intra-thoracic thrombi in Trousseau syndrome http://www.medworm.com/index.php?rid=3083508&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2968%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083508 Mon, 14 Dec 2009 08:06:55 +0100 3083508 Implantable cardioverter defibrillator and competitive sport participation http://www.medworm.com/index.php?rid=3083507&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2967%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083507 Mon, 14 Dec 2009 08:06:55 +0100 3083507 Inotropic therapy for heart failure: paradise lost http://www.medworm.com/index.php?rid=3083506&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2965%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083506 Mon, 14 Dec 2009 08:06:55 +0100 3083506 Anomalous connection of the inferior vena cava to the left atrium diagnosed using three-dimensional echocardiography http://www.medworm.com/index.php?rid=3083505&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2964%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083505 Mon, 14 Dec 2009 08:06:55 +0100 3083505 Peak exercise responses in heart failure: back to basics http://www.medworm.com/index.php?rid=3083504&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2962%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083504 Mon, 14 Dec 2009 08:06:55 +0100 3083504 CardioPulse Articles http://www.medworm.com/index.php?rid=3083503&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F24%2F2951%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3083503 Mon, 14 Dec 2009 08:06:54 +0100 3083503 Occurrence of late gadolinium enhancement in ventricular ballooning or Tako-Tsubo syndrome: increased wall stress should not be overlooked: reply http://www.medworm.com/index.php?rid=3040883&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2949%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040883 Tue, 01 Dec 2009 08:08:42 +0100 3040883 Occurrence of late gadolinium enhancement in ventricular ballooning or Tako-Tsubo syndrome: increased wall stress should not be overlooked http://www.medworm.com/index.php?rid=3040882&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2948%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040882 Tue, 01 Dec 2009 08:08:42 +0100 3040882 T-wave inversions in elite athletes: the best predictors have yet to be determined: reply http://www.medworm.com/index.php?rid=3040881&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2947-a%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040881 Tue, 01 Dec 2009 08:08:42 +0100 3040881 T-wave inversions in elite athletes: the best predictors have yet to be determined http://www.medworm.com/index.php?rid=3040880&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2947%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040880 Tue, 01 Dec 2009 08:08:42 +0100 3040880 Interleukin 18 gene promoter polymorphism: a link between hypertension and pre-hospital sudden cardiac death: the Helsinki Sudden Death Study http://www.medworm.com/index.php?rid=3040879&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2939%3Frss%3D1 Conclusion Hypertension interacts with IL-18 gene promoter –137 G/C polymorphism, affecting the risk of SCD and the development of coronary atherosclerosis. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040879 Tue, 01 Dec 2009 08:08:42 +0100 3040879 Cytomegalovirus colitis 5 years after heart transplantation http://www.medworm.com/index.php?rid=3040878&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2938%3Frss%3D1 (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040878 Tue, 01 Dec 2009 08:08:42 +0100 3040878 Expression of lipoprotein-associated phospholipase A2 in carotid artery plaques predicts long-term cardiac outcome http://www.medworm.com/index.php?rid=3040877&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2930%3Frss%3D1 Conclusion Lipoprotein-associated phospholipase A2 expression in carotid artery plaques is a predictor of long-term cardiac outcome. The current study supports the concept of atherosclerosis as a systemic disease with multi-focal complications and personalized medicine. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040877 Tue, 01 Dec 2009 08:08:42 +0100 3040877 Coronary CT angiography and myocardial perfusion imaging to detect flow-limiting stenoses: a potential gatekeeper for coronary revascularization? http://www.medworm.com/index.php?rid=3040876&cid=s_29161_7_f&fid=29161&url=http%3A%2F%2Feurheartj.oxfordjournals.org%2Fcgi%2Fcontent%2Fshort%2F30%2F23%2F2921%3Frss%3D1 Conclusion The combined non-invasive approach CTA/MPI has an excellent accuracy to detect flow-limiting coronary stenoses compared with QCA/MPI and its use as a gatekeeper appears to make a substantial part of revascularization procedures redundant. (Source: European Heart Journal) European Heart Journal journals http://www.medworm.com/rss/comments.php?id=3040876 Tue, 01 Dec 2009 08:08:42 +0100 3040876