MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'European Journal of Neurology' source. Sun, 21 Mar 2010 15:30:49 +0100 http://www.medworm.com/index.php?rid=3372006&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02974.x Conclusion: Our study suggests a familial susceptibility to AD amongst first-degree relatives of younger onset PD cases. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3372006 Wed, 17 Mar 2010 00:00:00 +0100 3372006 http://www.medworm.com/index.php?rid=3372005&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02995.x Conclusion: Intravenous thrombolysis, particularly in a lower dose, is safe and feasible in the treatment of acute IS in our selected Vietnamese population. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3372005 Wed, 17 Mar 2010 00:00:00 +0100 3372005 http://www.medworm.com/index.php?rid=3372004&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02977.x Conclusion: Our results complement previous reports that some patients with monoclonal gammopathy and polyneuropathy can develop solitary or disseminated signs of CNS involvement. It indicates that pathological effects of M-proteins are not necessarily restricted to the peripheral nervous system. The specificity and affinity of circulating M-protein to antigens in the CNS might be critical for the development of different clinical phenotypes. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3372004 Wed, 17 Mar 2010 00:00:00 +0100 3372004 http://www.medworm.com/index.php?rid=3372003&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02981.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3372003 Wed, 17 Mar 2010 00:00:00 +0100 3372003 http://www.medworm.com/index.php?rid=3372002&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02986.x Conclusions: In daily clinical practice, monotherapy or combination therapy with rasagiline is able to improve PD symptoms, reduce OFF time, and improve QoL, whilst demonstrating favourable tolerability. In addition, rasagiline has a simple dosing schedule of one tablet, once daily, with no titration. These results are consistent with the pivotal rasagiline clinical studies (TEMPO, LARGO and PRESTO). (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3372002 Wed, 17 Mar 2010 00:00:00 +0100 3372002 http://www.medworm.com/index.php?rid=3372001&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02991.x Dementia is a terminal disease, associated with great suffering and difficult decisions in the severe stage. The decision-making process is characterized by uncertainty because of lack of scientific evidence in treatments and by the need to reconcile conflicting points of view. In intercurrent diseases, aggressive interventions are used without consideration of its futility; in comparison with cancer, several consequences of physicians' attitude not to consider dementia as a terminal disease have been reported, especially concerning pain relief. Lack of evidence of artificial nutrition and hydration effectiveness makes advance care planning relevant. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3372001 Wed, 17 Mar 2010 00:00:00 +0100 3372001 http://www.medworm.com/index.php?rid=3372000&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02997.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3372000 Wed, 17 Mar 2010 00:00:00 +0100 3372000 http://www.medworm.com/index.php?rid=3371999&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02998.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3371999 Wed, 17 Mar 2010 00:00:00 +0100 3371999 http://www.medworm.com/index.php?rid=3361018&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02983.x Conclusions: This population had a lower incidence of CI compared to other population-based studies from Northern Europe and the United States. Furthermore, with the projected increase in the segment of the very old in the general population, our data indicate that both CI and IH will dramatically increase in the near future. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3361018 Sat, 13 Mar 2010 00:00:00 +0100 3361018 http://www.medworm.com/index.php?rid=3348448&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02996.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3348448 Wed, 10 Mar 2010 00:00:00 +0100 3348448 http://www.medworm.com/index.php?rid=3348453&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02978.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3348453 Tue, 09 Mar 2010 00:00:00 +0100 3348453 http://www.medworm.com/index.php?rid=3348452&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02980.x Conclusions: Our results suggest that corticolimbic degeneration occurs in non-demented patients with PD, and extensive involvement of the limbic and posterior cortical regions as well as the frontal cortices is associated with cognitive impairment in PD. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3348452 Tue, 09 Mar 2010 00:00:00 +0100 3348452 http://www.medworm.com/index.php?rid=3348451&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02985.x Conclusion: These guidelines are provisional, and the future availability of molecular genetic epidemiological data about the neurogenetic disorders under discussion in our article will allow improved recommendation with an increased level of evidence. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3348451 Tue, 09 Mar 2010 00:00:00 +0100 3348451 http://www.medworm.com/index.php?rid=3348450&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02989.x Conclusions: Dysautonomia occurs in approximately 10% of patients surviving severe TBI and is associated with DAI and the development of spasticity at follow-up. The initiation of dysautonomia by discomfort supports the Excitatory: Inhibitory Ratio model as pathophysiological mechanism. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3348450 Tue, 09 Mar 2010 00:00:00 +0100 3348450 http://www.medworm.com/index.php?rid=3348449&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02990.x Conclusions: The circulating level of hsCRP is associated with frontal lobe dysfunction in patients with cardiovascular risk factors independent of white matter lesions in brain MRI. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3348449 Tue, 09 Mar 2010 00:00:00 +0100 3348449 http://www.medworm.com/index.php?rid=3344583&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02969.x Conclusions: History and bedside examination are still fundamental to a correct diagnosis, whilst screening tools and questionnaires are useful in indicating probable NP; QST is also useful for indicating the latter, and to assess provoked pains and treatment response. Amongst laboratory tests, LEPs are the best tool for assessing A[delta] pathway dysfunction, and skin biopsy for assessing neuropathies with distal loss of unmyelinated nerve fibres. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3344583 Tue, 09 Mar 2010 00:00:00 +0100 3344583 http://www.medworm.com/index.php?rid=3333257&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02979.x Conclusion: Flexible-dose pregabalin 150[ndash]600 mg/day was effective in relieving neuropathic pain, improving disturbed sleep, improving overall patient status, and was generally well tolerated in patients with post-traumatic peripheral neuropathic pain. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3333257 Fri, 05 Mar 2010 00:00:00 +0100 3333257 http://www.medworm.com/index.php?rid=3333258&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02965.x Conclusion: Ten daily treatments of 1 and 25 Hz rTMS contralateral to the side of tinnitus have a greater beneficial effect on symptoms than either ipsilateral or left side stimulation. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3333258 Thu, 04 Mar 2010 00:00:00 +0100 3333258 http://www.medworm.com/index.php?rid=3324978&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02967.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3324978 Wed, 03 Mar 2010 00:00:00 +0100 3324978 http://www.medworm.com/index.php?rid=3324977&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02970.x Background: Viral encephalitis is a medical emergency. The prognosis depends mainly on the pathogen and host immunologic state. Correct immediate diagnosis and introduction of symptomatic and specific therapy has a dramatic influence upon survival and reduces the extent of permanent brain injury.Methods: We searched the literature from 1966 to 2009. Recommendations were reached by consensus. Where there was lack of evidence but consensus was clear, we have stated our opinion as good practice points.Recommendations: Diagnosis should be based on medical history and examination followed by CSF analysis for protein and glucose levels, cellular analysis, and identification of the pathogen by polymerase chain reaction amplification (recommendation level A) and serology (level B). Neuroimaging, p... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3324977 Wed, 03 Mar 2010 00:00:00 +0100 3324977 http://www.medworm.com/index.php?rid=3324976&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02975.x Conclusions: Caudate atrophy on MRI appears to be significantly greater in FTLD-FUS compared with FTLD-TDP and FTLD-TAU, suggesting that severe caudate atrophy may be a useful clinical feature to predict FTLD-FUS pathology. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3324976 Wed, 03 Mar 2010 00:00:00 +0100 3324976 http://www.medworm.com/index.php?rid=3319747&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02993.x Conclusion: Voltage-gated potassium channel antibodies might be involved in some cases of BE or MF. The common staining pattern despite different antibody results suggests that there might be other, as yet unidentified, antibodies associated with BE and MF. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3319747 Tue, 02 Mar 2010 00:00:00 +0100 3319747 http://www.medworm.com/index.php?rid=3319749&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02963.x Conclusion: Our study demonstrates that patients treated with tPA and leukoaraiosis on their baseline CT are at greater risk of sICH and have a worse functional outcome compared to patients without leukoaraiosis. It is important to note that these results should not lead to exclusion of patients with leukoaraiosis for tPA treatment. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3319749 Mon, 01 Mar 2010 00:00:00 +0100 3319749 http://www.medworm.com/index.php?rid=3319748&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02988.x Conclusion: DRD3 genotype and allelic variants were not related to the risk for migraine in Caucasian Spanish people. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3319748 Mon, 01 Mar 2010 00:00:00 +0100 3319748 http://www.medworm.com/index.php?rid=3317290&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02972.x Conclusions: The incidence and prevalence of ALS in the Iranian population seems to be lower compared to other populations and the survival of patients was longer than previously reported. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3317290 Mon, 01 Mar 2010 00:00:00 +0100 3317290 http://www.medworm.com/index.php?rid=3313221&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02976.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3313221 Sat, 27 Feb 2010 00:00:00 +0100 3313221 http://www.medworm.com/index.php?rid=3304451&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02973.x Conclusions: Autonomic symptoms are highly prevalent in patients with HD and may even precede the onset of motor signs. Moreover, autonomic dysfunction is related to functional disability and depression in HD. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3304451 Thu, 25 Feb 2010 00:00:00 +0100 3304451 http://www.medworm.com/index.php?rid=3300011&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02971.x Conclusions: Patients with MS had higher risk of multiple medical comorbidities compared to a matched control group in an ethnic Chinese population. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3300011 Wed, 24 Feb 2010 00:00:00 +0100 3300011 http://www.medworm.com/index.php?rid=3300016&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02952.x Conclusions: Our findings support the existence of a causative variant for MS within this candidate region in a representative Italian Caucasian population and, in particular, the role of the IL-1 beta ([minus]511 C/T) variant warrants further investigation. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3300016 Tue, 23 Feb 2010 00:00:00 +0100 3300016 http://www.medworm.com/index.php?rid=3300015&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02966.x Conclusion: The ITGB3 L33P seems to be unrelated to the development of OXLIPN, but it appears to be related to its severity. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3300015 Tue, 23 Feb 2010 00:00:00 +0100 3300015 http://www.medworm.com/index.php?rid=3300014&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02968.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3300014 Tue, 23 Feb 2010 00:00:00 +0100 3300014 http://www.medworm.com/index.php?rid=3300013&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02938.x Conclusions: These data suggest that the method of pain-related evoked potentials elicited by a nociceptive electrical stimulation of the skin may contribute to the early detection of diabetic sensory neuropathy. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3300013 Tue, 23 Feb 2010 00:00:00 +0100 3300013 http://www.medworm.com/index.php?rid=3300012&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02964.x Conclusion: TREX1 mutations do not play a role in the pathogenesis of sIBM. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3300012 Tue, 23 Feb 2010 00:00:00 +0100 3300012 http://www.medworm.com/index.php?rid=3281481&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02947.x Complex regional pain syndrome (CRPS), formerly known as Sudeck's dystrophy and causalgia, is a disabling and distressing pain syndrome. We here provide a review based on the current literature concerning the epidemiology, etiology, pathophysiology, diagnosis, and therapy of CRPS. CRPS may develop following fractures, limb trauma or lesions of the peripheral or CNS. The clinical picture comprises a characteristic clinical triad of symptoms including autonomic (disturbances of skin temperature, color, presence of sweating abnormalities), sensory (pain and hyperalgesia), and motor (paresis, tremor, dystonia) disturbances. Diagnosis is mainly based on clinical signs. Several pathophysiological concepts have been proposed to explain the complex symptoms of CRPS: (i) facilitated neurogenic infl... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3281481 Thu, 18 Feb 2010 00:00:00 +0100 3281481 http://www.medworm.com/index.php?rid=3260775&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02940.x Conclusions: Our study revealed the clinical features of non-hypertensive CAA-L-ICH, including its parietal predilection, which will require further study with a larger number of patients with different ethnic backgrounds. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260775 Thu, 11 Feb 2010 00:00:00 +0100 3260775 http://www.medworm.com/index.php?rid=3260774&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02941.x Conclusions: In addition to snoring, TBI and inflammatory responses are the two independent predictors for PB in patients with acute stroke. Clinicians should be encouraged to systematically evaluate TBI and inflammatory responses before PB in patients with acute stroke. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260774 Thu, 11 Feb 2010 00:00:00 +0100 3260774 http://www.medworm.com/index.php?rid=3260773&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02950.x Conclusions: This first study utilizing US in Bell's palsy highlights its role in outcome prediction and contributes to our understanding of recovery processes in this common neurological disorder. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260773 Thu, 11 Feb 2010 00:00:00 +0100 3260773 http://www.medworm.com/index.php?rid=3260772&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02960.x Background: Research suggests the prevalence of severe depression in ALS is (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260772 Thu, 11 Feb 2010 00:00:00 +0100 3260772 http://www.medworm.com/index.php?rid=3260782&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02953.x Discussion: Sensory electrophysiological demyelination is present and may be diagnostically useful in typical CIDP. SCB detection and SNAP duration prolongation appear to represent more useful markers of demyelination than SNCV reduction. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260782 Wed, 10 Feb 2010 00:00:00 +0100 3260782 http://www.medworm.com/index.php?rid=3260781&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02959.x In this study we evaluate body composition and nutritional status in GSDII, and assess whether these parameters changed during treatment.Methods: Seventeen patients with late-onset GSDII, aged 52.6 ± 16.8 years, received ERT for >18 months. Dietary habits and metabolic profiles of glucids, lipids, and proteins were assessed. Body composition was calculated using anthropometry and bioelectrical impedence analysis.Results: On inclusion, we found increased fat mass (FM) in five patients in severe disease stage; all had normal body mass index (BMI). FM correlated inversely, and lean mass (LM) directly, with creatine kinase, prealbumin and albumin levels. After treatment, BMI and FM significantly increased, while LM only showed a trend toward increase. Prealbumin and albumin levels increased a... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260781 Wed, 10 Feb 2010 00:00:00 +0100 3260781 http://www.medworm.com/index.php?rid=3260780&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02929.x Conclusion: The assignment of the locus for PKC to the pericentromeric region of chromosome 16 is confirmed and putatively narrowed in the present study. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260780 Wed, 10 Feb 2010 00:00:00 +0100 3260780 http://www.medworm.com/index.php?rid=3260779&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02949.x Conclusion: The K239N mutation is associated with autosomal dominant AD with a wide range of age of onset and incomplete penetrance at the age of 65, prominent behavioural features and slow progression. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260779 Wed, 10 Feb 2010 00:00:00 +0100 3260779 http://www.medworm.com/index.php?rid=3260778&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02956.x Conclusions: This study suggests that left temporal low-frequency rTMS has beneficial effects in left-sided and bilateral tinnitus, but not in right-sided tinnitus. In line with the results from earlier studies involving smaller samples, tinnitus duration was found to influence rTMS outcome. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260778 Wed, 10 Feb 2010 00:00:00 +0100 3260778 http://www.medworm.com/index.php?rid=3260777&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02957.x Conclusions: The data presented here revealed differentiated risk nature of the triglyceride level modifying natural gene variants. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260777 Wed, 10 Feb 2010 00:00:00 +0100 3260777 http://www.medworm.com/index.php?rid=3260776&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02845.x Conclusions: Stroke treatment in potential candidates for thrombolytic therapy revealed no impairment on weekend or at night already in 2003. During 4 years, it was possible to increase rate of rTPA treatment from 8.9% to 21.8% without increment of complications or death, confirming that rTPA is safe and can be implemented with full daily and weekly coverage. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3260776 Wed, 10 Feb 2010 00:00:00 +0100 3260776 http://www.medworm.com/index.php?rid=3237598&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02961.x Conclusion: IVT-treated SAO-patients died less often and reached independence more often than IVT-treated non-SAO-patients. However, the variable 'SAO' was a dependent rather than an independent outcome predictor. The absence of an excess in ICH indicates that IVT seems not to be harmful in SAO-patients. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3237598 Thu, 04 Feb 2010 00:00:00 +0100 3237598 http://www.medworm.com/index.php?rid=3237599&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02955.x Conclusions: The RF provided the best predictive performance amongst all of the tested models. We believe that the RF is a suitable tool for clinicians to use in predicting the 30-day mortality of patients after SICH. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3237599 Wed, 03 Feb 2010 00:00:00 +0100 3237599 http://www.medworm.com/index.php?rid=3233591&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02912.x Background: Hypertension is the most important modifiable risk factor for primary intracerebral hemorrhage (ICH), but little is known of the effect of preceding hypertension on outcome. Because high mean arterial blood pressure (MABP) at admission is an independent predictor of early death in patients with ICH, we explored its role on survival and poor outcome separately in normotensive subjects and subjects with treated and untreated hypertension.Methods: We assessed clinical data and the 3-month outcome of patients with spontaneous ICH (n = 453) admitted to the stroke unit of Oulu University Hospital between 1993 and 2004. Standard medical treatment was used to lower MABP from levels >127 mmHg to (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3233591 Wed, 03 Feb 2010 00:00:00 +0100 3233591 http://www.medworm.com/index.php?rid=3229277&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02951.x Background and purpose: These European Federation of Neurological Societies guidelines on neuroimaging of motor neuron diseases (MNDs) are designed to provide practical help for the neurologists to make appropriate use of neuroimaging techniques in patients with MNDs, which ranges from diagnostic and monitoring aspects to the in vivo study of the pathobiology of such conditions.Methods: Literature searches were performed before expert members of the Task Force wrote proposal. Then, consensus was reached by circulating drafts of the manuscript to the Task Force members and by discussion of the classification of evidence and recommendations.Results and conclusions: The use of conventional MRI in patients suspected of having a MND is yet restricted to exclude other causes of signs and symptom... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3229277 Tue, 02 Feb 2010 00:00:00 +0100 3229277 http://www.medworm.com/index.php?rid=3206504&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02932.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206504 Tue, 26 Jan 2010 00:00:00 +0100 3206504 http://www.medworm.com/index.php?rid=3206503&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02936.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206503 Tue, 26 Jan 2010 00:00:00 +0100 3206503 http://www.medworm.com/index.php?rid=3206502&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02937.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206502 Tue, 26 Jan 2010 00:00:00 +0100 3206502 http://www.medworm.com/index.php?rid=3206501&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02944.x Conclusion: Our data on a cohort of Chinese patients show some difference from descriptions in other ethnic groups. This includes an earlier age of onset, a lower incidence of depression and female serving as a predictor factor of a HRQL. Similar to other cohorts, DYT1 gene mutations are rare. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206501 Tue, 26 Jan 2010 00:00:00 +0100 3206501 http://www.medworm.com/index.php?rid=3206509&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02927.x Conclusion: Neuroimaging of the brain in a tertiary care center for patients with neurodevelopmental disorders of unknown origin is useful, especially in case of neurological symptoms/signs. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206509 Mon, 25 Jan 2010 00:00:00 +0100 3206509 http://www.medworm.com/index.php?rid=3206508&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02916.x Conclusions: This open-label study of pregabalin demonstrated efficacy that was consistent with that observed in previous controlled epilepsy trials. Pregabalin was well tolerated. The AE profile was also consistent with that reported in previous trials. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206508 Mon, 25 Jan 2010 00:00:00 +0100 3206508 http://www.medworm.com/index.php?rid=3206507&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02948.x Conclusions: The shorter disease duration of CJD patients with FMF may indicate the importance of pro-inflammatory factors in the disease. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206507 Mon, 25 Jan 2010 00:00:00 +0100 3206507 http://www.medworm.com/index.php?rid=3206506&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02954.x Conclusion: Hypocretin levels in patients with idiopathic RBD are normal. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206506 Mon, 25 Jan 2010 00:00:00 +0100 3206506 http://www.medworm.com/index.php?rid=3206505&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02958.x Conclusions: Feelings of tenseness, tremor severity and ADLs improved following unilateral or bilateral Vim DBS for ET. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3206505 Mon, 25 Jan 2010 00:00:00 +0100 3206505 http://www.medworm.com/index.php?rid=3199366&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02945.x Conclusions: Disorders of social communication justify systematic assessment in patients with TBI. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3199366 Sat, 23 Jan 2010 00:00:00 +0100 3199366 http://www.medworm.com/index.php?rid=3199368&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02939.x Background: One of the possible pathomechanisms of sudden death in epilepsy (SUDEP) is a postictal dysregulation of autonomic nervous system. We performed a heart rate variability (HRV) analysis of the periictal state to analyze whether a cardiac autonomic disturbance exists after an epileptic seizure.Methods: We included 31 periictal video[ndash]EEG[ndash]ECG recordings of 31 patients with epilepsy who had consecutively undergone pre-surgical evaluation. Nine generalized tonic-clonic (GTCS), 15 complex partial, and seven simple motor seizures were included. HRV was evaluated by analyzing 5-min-long ECG epochs, sampling from baseline, direct preictal, early-postictal ( (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3199368 Fri, 22 Jan 2010 00:00:00 +0100 3199368 http://www.medworm.com/index.php?rid=3199367&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2010.02935.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3199367 Fri, 22 Jan 2010 00:00:00 +0100 3199367 http://www.medworm.com/index.php?rid=3187284&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02928.x Conclusions: Iranian patients as a Caucasian population living in Asia seem to have the same clinical features in comparison with the reported studies from Western countries. Although the duration of follow-up was not too long, but they may possibly have a more benign course. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3187284 Wed, 20 Jan 2010 00:00:00 +0100 3187284 http://www.medworm.com/index.php?rid=3187283&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02942.x Conclusion: The overall lower risk seems to be predominantly related to the minor respiratory involvement in DM2, than in myotonic dystrophy type 1 (DM1). (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3187283 Wed, 20 Jan 2010 00:00:00 +0100 3187283 http://www.medworm.com/index.php?rid=3187282&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02943.x Conclusion: The management of Austrian CIS patients relies strongly on MRI findings and the physicians' interpretation of the patients' overall situation which, after 2 years, depends primarily on the course of the disease. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3187282 Wed, 20 Jan 2010 00:00:00 +0100 3187282 http://www.medworm.com/index.php?rid=3187281&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02946.x Conclusions: This is the first population-based epidemiologic study of Wilson's disease in Taiwan. Because of the effective and affordable treatment, the prevalence of Wilson's disease in Taiwan is expected to increase continuously. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3187281 Wed, 20 Jan 2010 00:00:00 +0100 3187281 http://www.medworm.com/index.php?rid=3169316&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02922.x Headache is one of the most common reasons for patients to visit their general practitioner. Most of these patients suffer from migraine, tension-type headache, or a combination of the two; they tend to self-medicate using over the counter combination headache preparations, particularly acetylsalicyclic acid (ASA) and acetaminophen coformulated with caffeine, which is one of the most commonly used combination analgesics in these patients worldwide. We reviewed studies on the efficacy and safety of this combination. In the treatment of migraine and tension-type headache, the combination of ASA, acetaminophen, and caffeine has been shown to be more efficacious and superior to monotherapy with the single substances of the combination. According to literature, there is no evidence for higher p... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3169316 Wed, 13 Jan 2010 00:00:00 +0100 3169316 http://www.medworm.com/index.php?rid=3169315&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02923.x Conclusion: Diabetes mellitus type 2 may delay the onset of motor symptoms in ALS. These findings support other studies suggesting a relationship between the pathophysiology of ALS and metabolic derangements. Further investigations are needed to ascertain whether manipulating metabolic parameters would improve outcomes in ALS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3169315 Wed, 13 Jan 2010 00:00:00 +0100 3169315 http://www.medworm.com/index.php?rid=3169314&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02931.x Conclusions: Despite the fact that the SCN9A gene is an excellent candidate, we did not find evidence that it plays a major role in familial CRPS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3169314 Wed, 13 Jan 2010 00:00:00 +0100 3169314 http://www.medworm.com/index.php?rid=3147515&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02924.x Conclusions: Perforating artery territorial infarction with RAA or PAA when compared to PAI without atherosclerosis showed different involvement patterns of systemic atherosclerosis, suggesting potentially different aetiological mechanisms. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3147515 Thu, 07 Jan 2010 00:00:00 +0100 3147515 http://www.medworm.com/index.php?rid=3147514&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02925.x Conclusions: These results suggest that there is no effect in carrying the rs10492972 C variant on the risk of disease as well as on the rate of disability progression in a cohort of Italian patients with PPMS and patients with PRMS. These data need to be confirmed in an independent sample of patients with progressive MS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3147514 Thu, 07 Jan 2010 00:00:00 +0100 3147514 http://www.medworm.com/index.php?rid=3147513&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02926.x Conclusions: Nearly one of every three patients with ET who had been prescribed medication for tremor had discontinued pharmacotherapy. Even more revealing was that a similar proportion of cases with severe tremor had stopped medication. These data make tangibly evident that there is a sizable population of patients with ET who are untreated and disabled, and underscore the inadequacy of current pharmacotherapeutic options for this common neurological disease. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3147513 Thu, 07 Jan 2010 00:00:00 +0100 3147513 http://www.medworm.com/index.php?rid=3131475&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02919.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131475 Thu, 31 Dec 2009 00:00:00 +0100 3131475 http://www.medworm.com/index.php?rid=3131483&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02900.x Parkinson's disease (PD) is most frequently associated with characteristic motor symptoms that are known to arise with degeneration of dopaminergic neurons. However, patients with this disease also experience a multitude of non-motor symptoms, such as sleep disturbances, fatigue, apathy, anxiety, depression, cognitive impairment, dementia, olfactory dysfunction, pain, sweating and constipation, some of which can be at least as debilitating as the movement disorders and have a major impact on patients' quality of life. Many of these non-motor symptoms may be evident prior to the onset of motor dysfunction. The neuropathology of PD has shown that complex, interconnected neuronal systems, regulated by a number of different neurotransmitters in addition to dopamine, are involved in the aetiolo... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131483 Wed, 30 Dec 2009 00:00:00 +0100 3131483 http://www.medworm.com/index.php?rid=3131482&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02906.x Conclusions: Significantly poorer outcomes for those scoring '1' on the F-Score suggest that only those scoring '0' should constitute a 'good' outcome in GBS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131482 Wed, 30 Dec 2009 00:00:00 +0100 3131482 http://www.medworm.com/index.php?rid=3131481&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02914.x Conclusions: PON1 polymorphisms are not related with the risk for ET. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131481 Wed, 30 Dec 2009 00:00:00 +0100 3131481 http://www.medworm.com/index.php?rid=3131480&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02905.x Conclusion: Our results indicate that although not a presenting symptom, IMA and IDA may be features of MSA and, to a lesser degree, of PD. Also, it seems to be unrelated to the motor features of patients with PD. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131480 Wed, 30 Dec 2009 00:00:00 +0100 3131480 http://www.medworm.com/index.php?rid=3131479&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02909.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131479 Wed, 30 Dec 2009 00:00:00 +0100 3131479 http://www.medworm.com/index.php?rid=3131478&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02910.x Conclusions: GHD persists long after the TBI, independently of trauma severity and age at traumatic event. GH secretion is more sensitive to TBI than other pituitary hormones. No evidence is found for an association of cognitive function impairment and somatotropic axis impairment in adult patients tested more than 1 year after the TBI. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131478 Wed, 30 Dec 2009 00:00:00 +0100 3131478 http://www.medworm.com/index.php?rid=3131477&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02917.x The objective of the current article was to review the literature and discuss the degree of evidence for various treatment strategies for status epilepticus (SE) in adults. We searched MEDLINE and EMBASE for relevant literature from 1966 to January 2005 and in the current updated version all pertinent publications from January 2005 to January 2009. Furthermore, the Cochrane Central Register of Controlled Trials (CENTRAL) was sought. Recommendations are based on this literature and on our judgement of the relevance of the references to the subject. Recommendations were reached by informative consensus approach. Where there was a lack of evidence but consensus was clear, we have stated our opinion as good practice points. The preferred treatment pathway for generalised convulsive status epil... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131477 Wed, 30 Dec 2009 00:00:00 +0100 3131477 http://www.medworm.com/index.php?rid=3131476&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02918.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3131476 Wed, 30 Dec 2009 00:00:00 +0100 3131476 http://www.medworm.com/index.php?rid=3127859&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02915.x Conclusions: The results confirm that spasticity is most common in the anti-gravity muscles and is associated with the control of voluntary movements. As the severity of spasticity also increased after 3 months, when neurally mediated spasticity is expected to have passed its peak, intrinsic muscle changes may play a larger role than neural components with the passage of time after stroke. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127859 Wed, 30 Dec 2009 00:00:00 +0100 3127859 http://www.medworm.com/index.php?rid=3127866&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02898.x Conclusions: These data suggest that other neurotransmitter systems apart from the nigro-striatal dopaminergic system are involved in the generation of Parkinsonian tremor, and they are consistent with previous evidence of a lack of correlation between tremor severity and FP-CIT uptake. Putaminal relative sparing in TD patients could partially explain the slower disease progression reported in this PD phenotype. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127866 Tue, 29 Dec 2009 00:00:00 +0100 3127866 http://www.medworm.com/index.php?rid=3127865&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02901.x Discussion: The introduction of a neurology consultant-designed and consultant-led intranet referral service has greatly enhanced the delivery of the consult service to patients in our hospital. This referral system contributes significantly to hospital efficiency and to access for patients to specialist assessment. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127865 Tue, 29 Dec 2009 00:00:00 +0100 3127865 http://www.medworm.com/index.php?rid=3127864&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2008.02903.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127864 Tue, 29 Dec 2009 00:00:00 +0100 3127864 http://www.medworm.com/index.php?rid=3127863&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2008.02904.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127863 Tue, 29 Dec 2009 00:00:00 +0100 3127863 http://www.medworm.com/index.php?rid=3127862&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02907.x Conclusion: The present results are in accordance with a lifelong secular improvement in cognitive performance. The operational cut-off values may change with time, which may have clinical impact in the diagnosis of disorders like mild cognitive impairment or dementia. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127862 Tue, 29 Dec 2009 00:00:00 +0100 3127862 http://www.medworm.com/index.php?rid=3127861&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02911.x Conclusions: The recently introduced FTLD-modified CDR scale correlates with the degree of frontotemporal hypoperfusion in patients with FTLD. This study confirms and further supports the usefulness of FTLD-modified CDR in future clinical trials to monitor disease progression. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127861 Tue, 29 Dec 2009 00:00:00 +0100 3127861 http://www.medworm.com/index.php?rid=3127860&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02913.x Conclusions: Spontaneous intracranial hypotension can be effectively cured by lumbar autologous EBP in Trendelenburg position pre-medicated with acetazolamide. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3127860 Tue, 29 Dec 2009 00:00:00 +0100 3127860 http://www.medworm.com/index.php?rid=3125554&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02889.x Conclusions: After three decades of disease, half of the MS patients experienced reduced cognitive functioning; however, nearly one-third of the patients were only mildly disabled based on the EDSS. Younger onset age was associated with higher prevalence of cognitive impairment. A thorough evaluation of cognitive function in addition to EDSS is essential for evaluating long-term impairment in patients with MS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3125554 Tue, 29 Dec 2009 00:00:00 +0100 3125554 http://www.medworm.com/index.php?rid=3125553&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02895.x Conclusions: Cerebral digital subtraction angiography is an effective and accurate method for examination of a DAVF at the foramen magnum. It can be treated effectively and with minimal surgical trauma by microsurgical electrocoagulation and disconnection of the shunt. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3125553 Tue, 29 Dec 2009 00:00:00 +0100 3125553 http://www.medworm.com/index.php?rid=3125555&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02873.x Background and purpose: These EFNS guidelines on the molecular diagnosis of neurogenetic disorders are designed to provide practical help for the general neurologist to make appropriate use of molecular genetics in diagnosing neurogenetic disorders.Methods: Literature searches were performed before expert members of the task force wrote proposals, which were discussed in detail until final consensus had been reached among all task force members.Results and conclusion: This paper provides updated guidelines for molecular diagnosis of two particularly complex groups of disorders, the ataxias and spastic paraplegias. Possibilities and limitations of molecular genetic diagnosis of these disorders are evaluated and recommendations are provided. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3125555 Mon, 28 Dec 2009 00:00:00 +0100 3125555 http://www.medworm.com/index.php?rid=3123854&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02893.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3123854 Mon, 28 Dec 2009 00:00:00 +0100 3123854 http://www.medworm.com/index.php?rid=3123857&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02894.x Conclusions: One-month intake of 5 mg/day folate normalizes plasma tHcy levels in all hyper-homocysteinemic PD patients. Following folate discontinuation, hyper-tHcy recurs in all patients within 4 months. Knowledge of this time interval is useful to optimize pulses of folate therapy in hyper-homocysteinemic patients with PD. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3123857 Sun, 27 Dec 2009 00:00:00 +0100 3123857 http://www.medworm.com/index.php?rid=3123856&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02902.x Conclusions: Even at time of diagnosis of a CSS, neurologic manifestations are common, especially as a multiplex mononeuropathy. With a consequent immunosuppressive therapy, new neurologic complications can be avoided for the most part. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3123856 Sun, 27 Dec 2009 00:00:00 +0100 3123856 http://www.medworm.com/index.php?rid=3123855&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02890.x Conclusion: The early detection of NAbs by CPE assay and the finding of only one serum sample with a NAb titre >100 TRU seem to be markers of low bioavailability of IFN-beta, whilst a twofold decrease in the MMP-9/TIMP-1 ratio by quantitative PCR assay seems to be a marker of high bioavailability of IFN-beta. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3123855 Sun, 27 Dec 2009 00:00:00 +0100 3123855 http://www.medworm.com/index.php?rid=3109490&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02908.x Conclusions: Considering synergistic effects between polymorphisms in oxidative stress-related genes may help in determining the risk profile for PD. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3109490 Tue, 22 Dec 2009 00:00:00 +0100 3109490 http://www.medworm.com/index.php?rid=3107550&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02897.x Conclusion: IFNB-1b treatment does not appear to be effective for preventing relapse in NMO likely because of differences between the immune-pathogenesis of NMO and MS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3107550 Mon, 21 Dec 2009 00:00:00 +0100 3107550 http://www.medworm.com/index.php?rid=3107549&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02899.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3107549 Mon, 21 Dec 2009 00:00:00 +0100 3107549 http://www.medworm.com/index.php?rid=3103249&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02892.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3103249 Sat, 19 Dec 2009 00:00:00 +0100 3103249 http://www.medworm.com/index.php?rid=3103255&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02866.x Conclusions: We conclude that the levodopa requirement in PD ranges considerably, and that men use higher levodopa dose than women. Levodopa requirement is constant during the progression of the disease in low-dose patients but increases in high-dose patients. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3103255 Fri, 18 Dec 2009 00:00:00 +0100 3103255 http://www.medworm.com/index.php?rid=3103254&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02867.x Conclusions: The clinical, MRI, and MRS findings suggest that the mechanisms responsible for NKHCB may be a reversible ischaemia insult potentiated by hyperglycemia. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3103254 Fri, 18 Dec 2009 00:00:00 +0100 3103254 http://www.medworm.com/index.php?rid=3103253&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02883.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3103253 Fri, 18 Dec 2009 00:00:00 +0100 3103253 http://www.medworm.com/index.php?rid=3103252&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02884.x Conclusions: This study suggests that the assessment and treatment of insomnia-related complaints should be considered in global management plans of patients with focal dystonia, particularly in those affected by BSP. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3103252 Fri, 18 Dec 2009 00:00:00 +0100 3103252 http://www.medworm.com/index.php?rid=3103251&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02885.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3103251 Fri, 18 Dec 2009 00:00:00 +0100 3103251 http://www.medworm.com/index.php?rid=3103250&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02891.x Conclusion: The number of missed referrals for epilepsy surgery evaluation was estimated to be 60 per 100 000 inhabitants. Several important obstacles were found for not referring patients for epilepsy surgery evaluation. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3103250 Fri, 18 Dec 2009 00:00:00 +0100 3103250 http://www.medworm.com/index.php?rid=3069007&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02896.x Background and purpose: The growth hormone (GH) and insulin-like growth factor (IGF) system may be involved in neurodegenerative processes, and some abnormalities have been reported in amyotrophic lateral sclerosis (ALS). Our aim was to investigate the GH[ndash]IGF axis in patients with ALS and evaluate correlations between this endocrine system and clinical features.Methods: Serum levels of GH, IGF-I, IGF-II, insulin, IGF-binding protein 1 (IGF-BP1), and IGF-binding protein 3 (IGF-BP3) were measured in 25 patients with ALS and 25 age-, gender-, and BMI-matched healthy controls. A GHRH plus arginine test was performed in patients and controls. Clinical status of patients was evaluated with the ALS Functional Rating Scale [ndash] Revised (ALSFRS-R) and upper motor neuron (UMN) score.Results... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3069007 Wed, 09 Dec 2009 00:00:00 +0100 3069007 http://www.medworm.com/index.php?rid=3069011&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02881.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3069011 Mon, 07 Dec 2009 00:00:00 +0100 3069011 http://www.medworm.com/index.php?rid=3069010&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02882.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3069010 Mon, 07 Dec 2009 00:00:00 +0100 3069010 http://www.medworm.com/index.php?rid=3069009&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02870.x Conclusions: There is an anticipation of the age at onset of MS in the younger generations of patients with familial MS. There is also a lower age at onset in familial versus sporadic MS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3069009 Mon, 07 Dec 2009 00:00:00 +0100 3069009 http://www.medworm.com/index.php?rid=3069008&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02888.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3069008 Mon, 07 Dec 2009 00:00:00 +0100 3069008 http://www.medworm.com/index.php?rid=3054484&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02844.x Conclusions: This observation suggests that a mutation in an LMNB1 regulatory sequence underlies the variant ADLD phenotype. Thus, adult forms of ADLD linked to 5q23 appear to be more heterogeneous clinically and genetically than previously thought. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3054484 Fri, 04 Dec 2009 00:00:00 +0100 3054484 http://www.medworm.com/index.php?rid=3024611&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02875.x Conclusions: These data suggest that some of the normal tremor exhibited by people in the population is likely to be subclinical, partially expressed ET and that the sphere of ET is wider than is apparent from a consideration of clinically diagnosed cases. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024611 Wed, 25 Nov 2009 00:00:00 +0100 3024611 http://www.medworm.com/index.php?rid=3024622&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02863.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024622 Tue, 24 Nov 2009 00:00:00 +0100 3024622 http://www.medworm.com/index.php?rid=3024621&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02868.x The incidence of cerebral infarction amongst patients (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024621 Tue, 24 Nov 2009 00:00:00 +0100 3024621 http://www.medworm.com/index.php?rid=3024620&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02869.x Conclusions: Post-ictal cerebral PCT abnormalities are relatively common in patients early after seizure. When PCT abnormalities occur in atypical vascular distributions [ndash] and the CTA shows no corresponding large vessel occlusions [ndash] seizure should be considered as a diagnostic possibility prior to giving acute stroke therapy. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024620 Tue, 24 Nov 2009 00:00:00 +0100 3024620 http://www.medworm.com/index.php?rid=3024619&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02872.x Conclusions: Our findings indicate that structural MRI combined with fully automated computational morphometric analyses represents an objective and observer-independent imaging tool for the representation of progressive striatal degeneration in MLS and might be a valuable methodology for cross-sectional as well as longitudinally volumetric studies in other rare neurodegenerative diseases, even on individual patients. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024619 Tue, 24 Nov 2009 00:00:00 +0100 3024619 http://www.medworm.com/index.php?rid=3024618&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02840.x Conclusions: In patients with BPS, the electrically induced muscle activation neither increases the effectiveness of BonT-A nor produces larger electrophysiological peripheral effects. The lack of BonT-A-induced changes in the blink reflex recovery cycle provides evidence that BonT-A therapy is safe in patients with BPS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024618 Tue, 24 Nov 2009 00:00:00 +0100 3024618 http://www.medworm.com/index.php?rid=3024617&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02850.x Conclusions: An increase in the number of female RR MS patients over time accounts for the increasing sex ratio of MS. This has implications for pathogenesis, for assessment of clinical trial results and for disease prevention. The factors underlying the selective increase in MS in females need to be uncovered. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024617 Tue, 24 Nov 2009 00:00:00 +0100 3024617 http://www.medworm.com/index.php?rid=3024616&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02853.x Conclusions: Autoimmune humoral response to neurocytoskeletal proteins is associated with ALS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024616 Tue, 24 Nov 2009 00:00:00 +0100 3024616 http://www.medworm.com/index.php?rid=3024615&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02854.x Conclusions: Nigrostriatal dopaminergic degeneration could be a part of the pathogenesis of RBD, but not essential for the development of RBD. The lack of correlation between RBD severity and DAT densities suggests that another pathogenic process not related to nigrostriatal dopaminergic transmission may be implicated in RBD. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024615 Tue, 24 Nov 2009 00:00:00 +0100 3024615 http://www.medworm.com/index.php?rid=3024614&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02861.x Conclusions: We show here that normal weight migraineurs exhibit independent of aura symptoms an atherogenic lipid profile, which shares common features with obesity-related lipid alterations. Our data suggest that migraine is associated with a higher risk for cardiovascular disease and its clinical consequences. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024614 Tue, 24 Nov 2009 00:00:00 +0100 3024614 http://www.medworm.com/index.php?rid=3024613&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02871.x Since the 1990s, China has experienced a boom in epilepsy surgery. Five cities have established epilepsy centers, and at least one hospital in each of the 32 provinces provides epilepsy surgical services. Epilepsy surgery in China has benefited from the availability of advanced non-invasive diagnostic tools to delineate epileptogenic lesions and epilepsy functional deficits, increased medical and social acceptance of epilepsy surgery, and collaborations with the International League Against Epilepsy, the International Bureau for Epilepsy, and international epilepsy centers. However, national demand for epilepsy surgery still far exceeds supply, and epilepsy surgery is underutilized in many economically underdeveloped provinces. This paper analyzes the current progress of epilepsy surgery i... European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024613 Tue, 24 Nov 2009 00:00:00 +0100 3024613 http://www.medworm.com/index.php?rid=3024612&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02874.x Conclusion: Abnormal ABI was associated with classical risk factors, especially hypertension. The measurement of ABI amongst patients with IS appeared to be useful to identify high-risk patients and plan adequate prevention therapies. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3024612 Tue, 24 Nov 2009 00:00:00 +0100 3024612 http://www.medworm.com/index.php?rid=3020770&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02865.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3020770 Tue, 24 Nov 2009 00:00:00 +0100 3020770 http://www.medworm.com/index.php?rid=3020772&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02860.x Conclusions: The PON2 311C allele was suggested as a possible predisposing factor for severe cases of ischemic stroke. Large-scale multicenter-controlled prospective studies are warranted to further explore the effects of PON polymorphisms on stroke susceptibility and severity. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3020772 Mon, 23 Nov 2009 00:00:00 +0100 3020772 http://www.medworm.com/index.php?rid=3020771&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02862.x Background: Lyme neuroborreliosis (LNB) is a nervous system infection caused by Borrelia burgdorferi sensu lato (Bb).Objectives: To present evidence-based recommendations for diagnosis and treatment.Methods: Data were analysed according to levels of evidence as suggested by EFNS.Recommendations: The following three criteria should be fulfilled for definite LNB, and two of them for possible LNB: (i) neurological symptoms; (ii) cerebrospinal fluid (CSF) pleocytosis; (iii) Bb-specific antibodies produced intrathecally. PCR and CSF culture may be corroborative if symptom duration is (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3020771 Mon, 23 Nov 2009 00:00:00 +0100 3020771 http://www.medworm.com/index.php?rid=3006076&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02846.x Conclusion: The incidence density of 1.76 per 100 000 suggests a low-median risk area for MS. This study constitutes the first of its kind to cover data of MS incidence in Argentina. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3006076 Thu, 19 Nov 2009 00:00:00 +0100 3006076 http://www.medworm.com/index.php?rid=3006077&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02859.x Conclusions: These results show that mutations in FUS are also a significant cause of familial ALS in Belgium. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3006077 Wed, 18 Nov 2009 00:00:00 +0100 3006077 http://www.medworm.com/index.php?rid=3001859&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02851.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001859 Wed, 18 Nov 2009 00:00:00 +0100 3001859 http://www.medworm.com/index.php?rid=3001858&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02852.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001858 Wed, 18 Nov 2009 00:00:00 +0100 3001858 http://www.medworm.com/index.php?rid=3001857&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02857.x Conclusions: The risk factor profiles and the work-up results are similar between the TIA and the stroke patients. These findings highlight the etiologic homogeneity of both conditions; therefore, justify their uniform management. In addition, low yield of CT in TIA patients was found, questioning thus the routine use of CT in work-up of TIA. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001857 Wed, 18 Nov 2009 00:00:00 +0100 3001857 http://www.medworm.com/index.php?rid=3001856&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02858.x Conclusion: CRFs acquired during long-term follow-up after CEA may independently contribute to progressive ICA stenosis after endarterectomy. Newly acquired CRFs might be more hazardous than CRFs present prior to CEA. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001856 Wed, 18 Nov 2009 00:00:00 +0100 3001856 http://www.medworm.com/index.php?rid=3001864&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02837.x Conclusions: Although this was a negative study, our findings disclosed a trend toward enhanced antiplatelet effects when cilostazol was added to aspirin in ischaemic stroke patients. Combination of aspirin and cilostazol might be a treatment option in the ischaemic stroke patients with AR. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001864 Tue, 17 Nov 2009 00:00:00 +0100 3001864 http://www.medworm.com/index.php?rid=3001863&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02836.x Discussion: In the absence of marked cognitive decline and disability, patients with ambulatory MS had a deficit interpreting social situations and performing in interpersonal contexts. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001863 Tue, 17 Nov 2009 00:00:00 +0100 3001863 http://www.medworm.com/index.php?rid=3001862&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02841.x Conclusions: Significant reductions in CSF TTR were found after cholinesterase inhibitor treatment in patients with AD compared to untreated individuals. CSF TTR was unaltered in patients with DLB and had no relationship to depression in the present cohort with dementias. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001862 Tue, 17 Nov 2009 00:00:00 +0100 3001862 http://www.medworm.com/index.php?rid=3001861&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02842.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001861 Tue, 17 Nov 2009 00:00:00 +0100 3001861 http://www.medworm.com/index.php?rid=3001860&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02849.x Conclusions: The results suggested that the chronic increase in rCBF in the right language-relevant areas is due at least in part to reduction in the trancallosal inhibitory activity of the language-dominant left hemisphere caused by the stroke lesion itself and that these relationships are not always symmetric. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=3001860 Tue, 17 Nov 2009 00:00:00 +0100 3001860 http://www.medworm.com/index.php?rid=2982968&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02810.x Conclusion: Cerebrospinal fluid biomarker analysis might point towards genetic analysis of PSEN1 in patients with positive family history and age of onset below 60 years. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2982968 Thu, 12 Nov 2009 00:00:00 +0100 2982968 http://www.medworm.com/index.php?rid=2982967&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02835.x Conclusions: Suggestions for improving the SCOPA-AUT include a shorter scale with a simpler response scheme and a combination of sexual items for men and women. The resulting SCOPA-AUT is a reliable scale, with good internal construct validity, providing Rasch transformed results on a linear metric scale. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2982967 Thu, 12 Nov 2009 00:00:00 +0100 2982967 http://www.medworm.com/index.php?rid=2982966&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02843.x Conclusions: Pre-treatment with AP is associated with an increased risk of PH after intravenous thrombolysis in patients with acute ischaemic stroke. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2982966 Thu, 12 Nov 2009 00:00:00 +0100 2982966 http://www.medworm.com/index.php?rid=2982965&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02838.x Conclusions: Statins pre-treatment of patients with intracerebral haemorrhage may provide better functional outcome at 3 months of acute onset. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2982965 Thu, 12 Nov 2009 00:00:00 +0100 2982965 http://www.medworm.com/index.php?rid=2982964&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02847.x Conclusions: Our findings show that the H1 haplotype is a significant risk factor for PD. However, one H1-specific SNP (rs242557) previously implicated in PSP did not alter the risk of PD, indicating that distinct H1 sub-haplotypes probably drive the associations with PD and PSP. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2982964 Thu, 12 Nov 2009 00:00:00 +0100 2982964 http://www.medworm.com/index.php?rid=2982963&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02848.x Conclusion: These results suggest that a peripheral molecular clock, as reflected in the dampened expression of the clock genes BMAL1 in total leukocytes, is altered in PD patients. In addition, the relative BMAL1 levels correlate positively with PD severity, which could provide a molecular basis to help monitor disease progression and response to investigational drugs. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2982963 Thu, 12 Nov 2009 00:00:00 +0100 2982963 http://www.medworm.com/index.php?rid=2982969&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02807.x Conclusion: Our results suggest that DBM could be a sensitive method for detecting morphological changes in early-stage PD. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2982969 Wed, 11 Nov 2009 00:00:00 +0100 2982969 http://www.medworm.com/index.php?rid=2975408&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02839.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2975408 Tue, 10 Nov 2009 00:00:00 +0100 2975408 http://www.medworm.com/index.php?rid=2975407&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02833.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2975407 Tue, 10 Nov 2009 00:00:00 +0100 2975407 http://www.medworm.com/index.php?rid=2975406&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02834.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2975406 Tue, 10 Nov 2009 00:00:00 +0100 2975406 http://www.medworm.com/index.php?rid=2936685&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02801.x Conclusions: Frontal-lobe mediated behavioral dysfunction appears to be common in ALS. Cognitively impaired ALS patients had greater behavioral dysfunction. Recognition of behavioral and cognitive dysfunction may assist health-care providers and care-givers recognize changes in decision-making capacity and treatment compliance of patients with ALS. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2936685 Thu, 29 Oct 2009 00:00:00 +0100 2936685 http://www.medworm.com/index.php?rid=2936689&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02816.x Conclusions: Donepezil and memantine have similar modest clinical and spectroscopic effect on mild to moderate AD. MRS could be useful to monitor progression of the disease. (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2936689 Wed, 28 Oct 2009 00:00:00 +0100 2936689 http://www.medworm.com/index.php?rid=2936688&cid=s_32226_25_f&fid=32226&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-1331.2009.02829.x (Source: European Journal of Neurology) European Journal of Neurology journals http://www.medworm.com/rss/comments.php?id=2936688 Wed, 28 Oct 2009 00:00:00 +0100 2936688