MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'European Journal of Pediatrics' source. Thu, 09 Feb 2012 01:09:29 +0100 http://www.medworm.com/index.php?rid=5669255&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb35q126v2g4588r5%2F Abstract  A 12-year-old girl of Turkish descent was referred 6 weeks after an influenza A infection because of persistent chest X-ray abnormalities compatible with interstitial lung disease. The clinically suspected diagnosis of pulmonary alveolar microlithiasis (PAM) supported by pathognomonic radiological abnormalities was confirmed by genetic analysis. The clinical presentation of PAM is illustrated by a case and review of the current literature on this subject: you only see what you know. Content Type Journal ArticleCategory Original ArticlePages 1-4DOI 10.1007/s00431-012-1678-8Authors M. Proesmans, Department of Pediatrics, University Hospital Leuven, Herestraat 49, 3000 Leuven, BelgiumM. Boon, Department of Pediatrics, University Hospital Leuven, Herestraat 4... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5669255 Mon, 06 Feb 2012 19:36:45 +0100 5669255 http://www.medworm.com/index.php?rid=5661237&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyk813173r7341558%2F In conclusion, piracetam is a safe and effective drug for the treatment of breath-holding spells in children. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00431-012-1680-1Authors Happy Sawires, Department of Pediatrics, Cairo University, Cairo, EgyptOsama Botrous, Department of Pediatrics, Beni-Suef University, Beni-Suef, Egypt Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5661237 Thu, 02 Feb 2012 18:12:29 +0100 5661237 http://www.medworm.com/index.php?rid=5661238&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F72212056218122g8%2F In conclusion, RSV hospitalisation in moderately prematurely born infants is associated with increased health-related cost of care. Nevertheless, if RSV prophylaxis is to be cost-effective, a high risk group of moderately prematurely born infants needs to be identified. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-012-1673-0Authors Deena Shefali-Patel, Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allergic Mechanisms of Asthma, King’s College London, London, UKMireia Alcazar Paris, Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allergic Mechanisms of Asthma, King’s College London, London, UKFran Watson, Division of Asthma, Allergy and Lung Biology, MRC Asthma Centre for Allergic Mechanisms of Asthma... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5661238 Thu, 02 Feb 2012 18:12:28 +0100 5661238 http://www.medworm.com/index.php?rid=5661240&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe672380102512nut%2F Abstract  A 2-month-old infant was admitted to hospital because of recurrent vomiting for 1 week, progressive apathy, and focal seizures. The cranial MRI showed a noticeable result. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00431-012-1681-0Authors Alexander Larsen, Department of General Pediatrics and Neonatology, University Hospital of Saarland, Kirrbergerstr. Building 9, 66421 Homburg, GermanyChristine Martin, Department of General Pediatrics and Neonatology, University Hospital of Saarland, Kirrbergerstr. Building 9, 66421 Homburg, GermanySascha Meyer, Department of General Pediatrics and Neonatology, University Hospital of Saarland, Kirrbergerstr. Building 9, 66421 Homburg, GermanyTilman Rohrer, Department of General Pediatrics and Neo... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5661240 Thu, 02 Feb 2012 18:12:27 +0100 5661240 http://www.medworm.com/index.php?rid=5661239&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx236p121556u4463%2F In this report, we present the clinical phenotype in patients with aberrations of chromosomes 7p and 18p and reviewed the literature to summarize cardiovascular malformations in these patients. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-012-1682-zAuthors Beate Schmidt, Children’s Hospital Cologne, Cologne, GermanyFloris Udink ten Cate, Department of Pediatric Cardiology, University of Cologne, Cologne, GermanyMichael Weiß, Children’s Hospital Cologne, Cologne, GermanyUdo Koehler, MGZ, Munich, Germany Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5661239 Thu, 02 Feb 2012 18:12:27 +0100 5661239 http://www.medworm.com/index.php?rid=5661241&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4820833l1260k425%2F Abstract  People with type 1 diabetes mellitus are at an increased risk of cardiovascular mortality. Studies comparing arterial stiffness between subjects with type 1 diabetes and nondiabetic controls have provided controversial findings. We investigated brachial–ankle pulse wave velocity (baPWV) in 87 teenagers with type 1 diabetes mellitus and in 21 matched healthy controls. Our data show that baPWV was not increased in teenagers after a median illness of 5 years Content Type Journal ArticleCategory Short CommunicationPages 1-4DOI 10.1007/s00431-012-1679-7Authors Mei-Ching Yu, Department of Paediatric Nephrology, Chang Gung Children’s Hospital, Lin-Kou Medical Center and Chang Gung University College of Medicine, Taoyuan, TaiwanFu-Sung Lo, Department of Paedi... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5661241 Thu, 02 Feb 2012 06:54:50 +0100 5661241 http://www.medworm.com/index.php?rid=5661242&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw5117762743r8181%2F Conclusion: The rarity of the disorder and the heterogeneous nature of its clinical manifestation predispose to a late diagnosis and delayed treatment. Our report highlights the fact that the condition can and does occur in a pediatric population in Europe and hence must be considered in patients presenting with suggestive symptoms and signs, especially in young patients with unexplained hypertension. Clinical suspicion and proper imaging are crucial for the correct diagnosis and management of patients with TA. A brief review of literature completes this report. Content Type Journal ArticleCategory Case ReportPages 1-7DOI 10.1007/s00431-012-1674-zAuthors Elżbieta Sadurska, Department of Pediatric Cardiology, Medical University of Lublin, ul. Chodźki 2, 20-093 Lublin, PolandRen... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5661242 Tue, 31 Jan 2012 07:06:39 +0100 5661242 http://www.medworm.com/index.php?rid=5661243&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd3078072001r6348%2F Content Type Journal ArticleCategory Acknowledgement to our ReviewersPages 1-4DOI 10.1007/s00431-012-1677-9 Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5661243 Tue, 31 Jan 2012 07:06:38 +0100 5661243 http://www.medworm.com/index.php?rid=5651299&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr4qm70927k7mp111%2F Abstract  A 7-year-old girl was admitted with a severe abdominal pain. Abdominal ultrasound and CT revealed a large splenic infarction, leading to the diagnosis of chronic myeloid leukemia. Content Type Journal ArticleCategory Images in PediatricsPages 1-2DOI 10.1007/s00431-012-1675-yAuthors David Drummond, Department of Pediatric Hematology and Oncology, Hôpital Armand Trousseau, Assistance Publique Hôpitaux de Paris (APHP), Université Pierre et Marie Curie (Paris 6), 26, avenue Arnold Netter, 75012 Paris, FranceMarion Lenoir, Department of Radiology, Hôpital Armand Trousseau, Assistance Publique Hôpitaux de Paris (APHP), Université Pierre et Marie Curie (Paris 6), 26, avenue Arnold Netter, 75012 Paris, FranceArnaud Y. Petit, Department of Pediatric Hematology and ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5651299 Thu, 26 Jan 2012 06:44:12 +0100 5651299 http://www.medworm.com/index.php?rid=5639896&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc486138w02772115%2F Conclusion: We assume that the homozygous alteration M348K is a harmless variant rather than a CF-causing mutation. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00431-012-1672-1Authors Julia Hentschel, Institute of Human Genetics, Jena University Hospital, Kollegiengasse 10, 07743 Jena, GermanyGabriele Riesener, Institute of Human Genetics, Jena University Hospital, Kollegiengasse 10, 07743 Jena, GermanyHeike Nelle, Institute of Human Genetics, Jena University Hospital, Kollegiengasse 10, 07743 Jena, GermanyManfred Stuhrmann, Institute of Human Genetics, Hannover Medical School, Jena, GermanyAnja Schöner, Institute of Human Genetics, Hannover Medical School, Jena, GermanyOlaf Sommerburg, Division of Pediatric Pulmonology & Allergy and CF Centre, Univer... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5639896 Tue, 24 Jan 2012 12:27:32 +0100 5639896 http://www.medworm.com/index.php?rid=5639897&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft233q7k3k7t49275%2F This report highlights the broad phenotypic variability of mitochondrial encephalopathies with juvenile onset. It shows that m.3243A>G mutations can cause classical MERRF and emphasises the significance of comprehensive genetic studies if mitochondrial disease is suspected clinically. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00431-011-1662-8Authors Florian Brackmann, Department of Pediatrics, Friedrich-Alexander-University of Erlangen–Nuremberg, Loschgestrasse 15, 91054 Erlangen, GermanyAngela Abicht, Medical Genetic Center, Munich, GermanyUwe Ahting, Department Klinische Chemie, Städtisches Klinikum, Munich, GermanyRolf Schröder, Friedrich-Alexander-University of Erlangen-Nuremberg, Institute of Neuropathology, Erlangen, Bavaria, GermanyRegina... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5639897 Tue, 24 Jan 2012 07:54:08 +0100 5639897 http://www.medworm.com/index.php?rid=5612065&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj456p211655p0347%2F Abstract  The prevalence of autism spectrum disorder (ASD) has increased considerably in the past decades. The primary care paediatrician plays an important role not only in the early recognition of ASD but also in its chronic management. Paediatricians need to be comfortable with the global care of children with ASD. The diagnostic assessment of children with ASD comprises the medical investigations to identify associated or underlying medical conditions. The most important associated conditions are seizures, feeding and gastrointestinal problems, sleep disturbances and dental abnormalities. The care of ASD patients is very demanding since along with the purely medical issues there are challenging behavioural and psychiatric conditions that need consideration and professio... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5612065 Tue, 17 Jan 2012 07:13:58 +0100 5612065 http://www.medworm.com/index.php?rid=5599944&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F62q5832845237271%2F Content Type Journal ArticleCategory Images in PediatricsPages 1-1DOI 10.1007/s00431-011-1664-6Authors A. A. M. Huiberts, AMC, Amsterdam, NetherlandsR. E. van Gelder, AMC, Amsterdam, NetherlandsJ. C. H. Wilde, AMC, Amsterdam, Netherlands Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5599944 Fri, 13 Jan 2012 16:58:20 +0100 5599944 http://www.medworm.com/index.php?rid=5599945&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq0607450304mr434%2F Abstract  In the recent past, hereditary podocytopathies have increasingly been recognized to be involved in the development of steroid-resistant nephrotic syndrome (SRNS). Mutations in podocyte genes substantially alter the development and structural architecture of the podocyte including its interdigitating foot processes. These constitute the basis of the slit diaphragm which is an essential part of the glomerular filtration barrier. Depending on the affected protein, the clinical course is variable with respect to onset and severity of the disease as well as treatment options. In general, hereditary podocytopathies are associated with a poorer renal outcome than the non-genetic variants. In addition, they require a different approach with respect to the applied therapeu... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5599945 Thu, 12 Jan 2012 06:42:57 +0100 5599945 http://www.medworm.com/index.php?rid=5585796&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F114x6715636ju6rv%2F Conclusion: The inverse relationship between sleep duration and BMI is mainly explained by the association between sleep duration and FM. Insulin may explain part of this association, in particular at the upper tail of the BMI distribution. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00431-011-1670-8Authors Claudia Börnhorst, Department of Biometry and Data Management, BIPS - Institute for Epidemiology and Prevention Research, University of Bremen, Bremen, GermanySabrina Hense, Department of Epidemiological Methods and Etiologic Research, BIPS - Institute for Epidemiology and Prevention Research, University of Bremen, Bremen, GermanyWolfgang Ahrens, Department of Epidemiological Methods and Etiologic Research, BIPS - Institute for Epidemiology and ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5585796 Wed, 11 Jan 2012 17:55:13 +0100 5585796 http://www.medworm.com/index.php?rid=5585797&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc797741x18836248%2F Conclusions: Despite the availability of laronidase since 2003, the diagnosis of MPS I is still substantially delayed for patients with Hurler–Scheie and Scheie phenotypes, which can lead to a sub-optimal treatment outcome. Increased awareness of MPS I signs and symptoms by primary care providers and pediatric subspecialists is crucial to initiate early treatment and to improve the quality of life of MPS I patients. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00431-011-1644-xAuthors Kristin D’Aco, Section of Metabolic Diseases, Children’s Hospital of Philadelphia, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USALisa Underhill, Genzyme, a Sanofi Company, Cambridge, MA, USALakshmi Rangachari, Genzyme, a Sanofi Company, Cambridge, MA, USA... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5585797 Tue, 10 Jan 2012 17:00:00 +0100 5585797 http://www.medworm.com/index.php?rid=5585799&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb66wvr7418006538%2F Conclusion. Severe EVW at preschool age has a high risk of asthma at age 5–10 years, and this is reinforced by a positive family history of asthma and to elevated FeNO levels. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00431-011-1663-7Authors Lucie Kappelle, Princess Amalia Children’s Clinic, Isala klinieken, PO Box 10400, 8000 GK, Zwolle, the NetherlandsPaul L. P. Brand, Princess Amalia Children’s Clinic, Isala klinieken, PO Box 10400, 8000 GK, Zwolle, the Netherlands Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5585799 Tue, 10 Jan 2012 16:59:59 +0100 5585799 http://www.medworm.com/index.php?rid=5585798&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F46247g7v17637l5q%2F Conclusion Propranolol appears highly efficacious in the management of infantile hepatic hemangioma; dedicated MRI is essential in confirming the diagnosis and monitoring of treatment. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00431-011-1671-7Authors Thangamadhan Bosemani, Division of Pediatric Radiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, 600 North Wolfe Street, Nelson Basement, B-172, Baltimore, MD 21287-0842, USAKatherine B. Puttgen, Division of Pediatric Dermatology, Department of Dermatology, Johns Hopkins Hospital, 600 North Wolfe Street, Nelson Basement, B-172, Baltimore, MD 21287-0842, USAThierry A. G. M. Huisman, Division of Pediatric Radiology, Department of Radiology and Radiological Science, Johns... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5585798 Tue, 10 Jan 2012 16:59:59 +0100 5585798 http://www.medworm.com/index.php?rid=5585800&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3n5840881p584864%2F Abstract  The aims were to summarize the experience and to determine the performance metrics of newborn screening (NBS) for congenital adrenal hyperplasia (CAH) in the Czech Republic. 17-Hydroxyprogesterone (17OHP) was measured in NBS samples prospectively in 545,026 newborns and retrospectively in 31 CAH patients born outside the study period. A total of 2,811 screened newborns had abnormal 17OHP; CAH was confirmed in 46 probands. One patient with a severe–moderate genotype of CAH had 17OHP below the cut-off and was diagnosed clinically. This corresponds to a screening sensitivity of 98% and a false positive rate (FPR) of 0.51%. The median of 17OHP in the most severe genotypes was 484 nmol/L (n = 21); in severe/moderate, 321 nmol/L (n = 30); in moderate,... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5585800 Tue, 10 Jan 2012 16:59:58 +0100 5585800 http://www.medworm.com/index.php?rid=5573466&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2022l14306045534%2F Conclusion: Sensorineural hearing loss is an uncommonly reported complication of KD. Pediatricians should be aware of this potential complication to allow for early intervention. Content Type Journal ArticleCategory Short CommunicationPages 1-4DOI 10.1007/s00431-011-1667-3Authors Ana Novo, Pediatrics Department, Centro Hospitalar do Porto, Largo Prof. Abel Salazar, 4099-001 Porto, PortugalSusana Pinto, Pediatrics Department, Centro Hospitalar do Porto, Largo Prof. Abel Salazar, 4099-001 Porto, PortugalAna Catarina Prior, Pediatrics Department, Centro Hospitalar do Porto, Largo Prof. Abel Salazar, 4099-001 Porto, PortugalSílvia Álvares, Pediatric Cardiology Department, Centro Hospitalar do Porto, Porto, PortugalTeresa Soares, Otorhinolaryngology Department, Centro Hospitalar do Po... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5573466 Fri, 06 Jan 2012 16:49:34 +0100 5573466 http://www.medworm.com/index.php?rid=5573467&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc704u3p386548864%2F In conclusion, our study suggested that DiffNaCl and Cl–Na ratio are simple and fast, and may be an alternative method to complex Stewart’s physiochemical approach in identifying raised UMA and TA in critically ill neonates. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-011-1666-4Authors Abdullah Kurt, Department of Pediatrics, Division of Neonatology, Baskent University Faculty of Medicine, Ankara, TurkeyAyşe Ecevit, Department of Pediatrics, Division of Neonatology, Baskent University Faculty of Medicine, Ankara, TurkeyServet Ozkiraz, Department of Pediatrics, Division of Neonatology, Antalya Education and Research Hospital, Antalya, TurkeyDeniz Anuk Ince, Department of Pediatrics, Division of Neonatology, Baskent University Faculty of Med... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5573467 Wed, 04 Jan 2012 06:58:17 +0100 5573467 http://www.medworm.com/index.php?rid=5573468&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft357t77871233154%2F Abstract  Chorioamnionitis is a known risk factor for neurological damage in newborns. The present study aimed at assessing the changes in cerebral blood flow velocity (CBFV) in early-onset neonatal sepsis (EONS) and determining its predictive value as well as prognostic significance. Inborn neonates with antenatal risk factors for chorioamnionitis were followed up for development of EONS, diagnosed by presence of clinical signs along with positive blood culture and/or elevated interleukin-6 (IL-6) concentrations (≥50 pg/mL) in umbilical cord blood. Comparison group was formed by asymptomatic neonates who had risk factors for chorioamnionitis but did not develop EONS and cord blood IL-6 concentrations were <50 pg/mL. CBFV (resistance and pulsatility indices, p... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5573468 Wed, 04 Jan 2012 06:58:16 +0100 5573468 http://www.medworm.com/index.php?rid=5562746&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr1447066l8625561%2F Conclusions: The findings of this study suggest that FE and SS provide a superior analgesia in preterm neonates during procedural pain. In particular, sensorial saturation seems to be an important non-pharmacological alternative treatment to prevent and reduce the procedural pain in preterm newborn. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-011-1655-7Authors Eloisa Gitto, Neonatal Intensive Care Unit, Department of Pediatrics, University of Messina, Via Consolare Valeria, CAP 98100 Messina, ItalySalvatore Pellegrino, Ph.D. Fellowship in Clinical and Bio-molecular Hepato-Gastroenterology of Paediatric and Adult Age, University Hospital “G. Martino”, Messina, ItalyMaria Manfrida, Neonatal Intensive Care Unit, Department of Pediatrics, Unive... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5562746 Fri, 30 Dec 2011 07:11:09 +0100 5562746 http://www.medworm.com/index.php?rid=5562747&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F97w1556651q64553%2F This study is the first to evaluate the way TT is done in daycare centers. A questionnaire was sent to 1,500 daycare centers, of which 429 replied (response rate of 28.6%). The results show that half of the childcare workers base the decision to start TT on readiness signs. The combination of age and readiness signs is used by 44.5%. The majority of the respondents spent more than 1 h per day on TT (81.8%); 79.8% considered that daycare and parents should play an equal role in TT. However, more than a third of the respondents thought that parents pass the responsibility for TT on to daycare and that not enough attention was paid to TT in the home. Most respondents stated that daycare centers had the facilities and means to be able to give the children proper TT (88.5%). Other re... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5562747 Fri, 30 Dec 2011 07:11:08 +0100 5562747 http://www.medworm.com/index.php?rid=5562748&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq965v3348j374717%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1657-5Authors Rashmi Ranjan Das, Department of Pediatrics, All India Institute of Medical Sciences (AIIMS), New Delhi, 110029 India Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5562748 Fri, 30 Dec 2011 07:11:07 +0100 5562748 http://www.medworm.com/index.php?rid=5553908&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F846480q276km32mk%2F Abstract  In spite of recent advances in perinatal care and an increase in survival of extremely preterm infants over the last few years, there remains a lack of consensus about practical aspects of resuscitation of extremely preterm infants born before 27 weeks’ gestation. With this in the background, the working group of one of the Perinatal Networks in London, UK, set out to conduct a survey to explore the opinions of the doctors and nurses on resuscitation practices of infants born before 27 weeks’ gestation, with the aim of developing consensus guidelines. The working group emailed a questionnaire to all neonatal units within the Perinatal Network to seek the views of paediatric medical and nursing staff on resuscitation of infants born at <27 week... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5553908 Wed, 28 Dec 2011 16:45:49 +0100 5553908 http://www.medworm.com/index.php?rid=5553909&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy62wq6p3p0401132%2F Conclusions. Exclusive breastfeeding is associated with reduced irritability/colic and a tendency toward longer nocturnal sleep. Breast milk (nocturnal) consists of substantial melatonin levels, whereas artificial formulas do not. We speculate that melatonin which is supplied to the infant via breast milk plays a role in improving sleep and reducing colic in breast-fed infants compared to formula-fed ones. Content Type Journal ArticleCategory Short CommunicationPages 1-4DOI 10.1007/s00431-011-1659-3Authors Anat Cohen Engler, Sleep Lab, Rambam Medical Center, Haifa, IsraelAmir Hadash, Pediatrics Department A, Meyer Children’s Hospital, Rambam Medical Center, Haifa, IsraelNaim Shehadeh, Pediatrics Department A, Meyer Children’s Hospital, Rambam Medical Center, Haifa, IsraelGio... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5553909 Wed, 28 Dec 2011 16:45:48 +0100 5553909 http://www.medworm.com/index.php?rid=5553910&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpj28914l47g2w317%2F Conclusions: Presence of MMP2/9 in the urine of infants <1 year can be explained by high rate of physiological tissue remodelling. Unexpectedly, MMP2 was lower in the urine of haemangioma patients and higher 2 weeks after propranolol treatment. Taking this and the diverse results in literature into account, the correlation between MMPs, proliferation, and regression of haemangiomas and propranolol remains unclear. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00431-011-1660-xAuthors C. J. Kleber, Devision of Paediatric Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, GermanyA. Spiess, Devision of Paediatric Surgery, University Hospital Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, GermanyJ. B. K... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5553910 Wed, 28 Dec 2011 06:52:31 +0100 5553910 http://www.medworm.com/index.php?rid=5553911&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx16k214514282467%2F In conclusion, the serious side effects of the nasal drops should have been explained to the family, and their long-term use should have been refrained. Content Type Journal ArticleCategory Case ReportPages 1-2DOI 10.1007/s00431-011-1645-9Authors Veysel Nijat Baş, Clinics of Pediatric Endocrinology, Dr. Sami Ulus Research and Training Hospital of Women’s and Children’s Health and Diseases, Ankara, TurkeySemra Çetinkaya, Clinics of Pediatric Endocrinology, Dr. Sami Ulus Research and Training Hospital of Women’s and Children’s Health and Diseases, Ankara, TurkeyZehra Aycan, Clinics of Pediatric Endocrinology, Dr. Sami Ulus Research and Training Hospital of Women’s and Children’s Health and Diseases, Ankara, Turkey Journal European Journal of PediatricsOnline ISSN... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5553911 Wed, 28 Dec 2011 06:52:30 +0100 5553911 http://www.medworm.com/index.php?rid=5553912&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd5v1241u27172316%2F Conclusion: These results suggest that prolonging inflation times during face mask resuscitation of prematurely born infants would not improve ventilation as prolonged inflation did not lead to longer inflation flow times. Content Type Journal ArticleCategory Original ArticlePages 1-4DOI 10.1007/s00431-011-1661-9Authors Vadivelam Murthy, Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King’s College London, London, UKNatasha Creagh, Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King’s College London, London, UKJanet L. Peacock, Department of Primary Care and Public Health Sciences, King’s College London, London, UKGrenville Fox, Evelina Children’s Hospital Neonata... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5553912 Wed, 28 Dec 2011 06:52:28 +0100 5553912 http://www.medworm.com/index.php?rid=5553913&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl35q0872857l25n2%2F Abstract  Palivizumab utilization, compliance, and outcomes were examined in infants with preexisting medical diseases within the Canadian Registry Database (CARESS) to aid in developing guidelines for potential “at-risk” infants in the future. Infants who received ≥1 dose of palivizumab during the 2006–2010 respiratory syncytial virus (RSV) seasons at 29 sites were recruited and utilization, compliance, and outcomes related to respiratory infection/illness (RI) events were collected monthly. Hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated for premature infants ≤35 completed weeks gestational age (GA) who met standard approval criteria (group 1) compared to those with medical disorders (group 2) using Cox proportional hazards regression mode... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5553913 Tue, 27 Dec 2011 17:00:29 +0100 5553913 http://www.medworm.com/index.php?rid=5546187&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft654725663823550%2F Abstract  Meckel’s diverticulum has varied presentations in children and often becomes a diagnostic challenge. The authors present a 10-year-old boy with abdominal pain and one episode of melena. His symptoms were undervalued during two previous hospitalizations in pediatric units until his hemoglobin level dropped from 8.2 to 3.5 g/dL. The laparoscopic intervention performed in emergency identified a bleeding Meckel’s diverticulum that was resected after being exteriorized from the umbilicus. Our observation shows that severe hemorrhage due to a Meckel’s diverticulum is possible albeit exceptional. Content Type Journal ArticleCategory Case ReportPages 1-2DOI 10.1007/s00431-011-1652-xAuthors C. Esposito, Department of Pediatrics, Federico II University of Na... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5546187 Fri, 23 Dec 2011 06:49:14 +0100 5546187 http://www.medworm.com/index.php?rid=5546188&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj7867l0618387421%2F Conclusions. A clinical pathway for the management of acute bronchiolitis can be implemented in the hospital setting and the conservative approach, in particular not prescribing bronchodilators, is not associated with prolonged duration of stay. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00431-011-1653-9Authors Claire Walker, Child Health Royal Aberdeen Children’s Hospital, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZG UKSusan Danby, Child Health Royal Aberdeen Children’s Hospital, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZG UKSteve Turner, Child Health Royal Aberdeen Children’s Hospital, University of Aberdeen, Foresterhill, Aberdeen, AB25 2ZG UK Journal European Journal of PediatricsOnline ISSN 1432-1076Print I... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5546188 Fri, 23 Dec 2011 06:49:13 +0100 5546188 http://www.medworm.com/index.php?rid=5546189&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj31738128265k530%2F Reply to the correspondence letter: "Hyperbilirubinemia in breastfed term neonates" Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1658-4Authors Ying-Juang Chen, Department of Pediatrics, Taipei Medical University Hospital, Taipei, TaiwanWei-Chuan Chen, Department of Pediatrics, Taipei Medical University Hospital, Taipei, TaiwanChung-Ming Chen, Department of Pediatrics, Taipei Medical University Hospital, Taipei, Taiwan Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5546189 Wed, 21 Dec 2011 20:08:50 +0100 5546189 http://www.medworm.com/index.php?rid=5516715&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd7r67605v5094g46%2F In conclusion, further studies are required to identify the optimum mode of CPAP generation and it is important that prematurely born infants are weaned from CPAP as soon as possible. Content Type Journal ArticleCategory ReviewPages 1-8DOI 10.1007/s00431-011-1648-6Authors Olie Chowdhury, Division of Asthma, Allergy & Lung Biology, MRC-Asthma UK Centre in Allergic Mechanisms of Asthma, King’s College, London, UKCatherine J. Wedderburn, Division of Asthma, Allergy & Lung Biology, MRC-Asthma UK Centre in Allergic Mechanisms of Asthma, King’s College, London, UKDonovan Duffy, Division of Asthma, Allergy & Lung Biology, MRC-Asthma UK Centre in Allergic Mechanisms of Asthma, King’s College, London, UKAnne Greenough, King’s College Hospital, 4th Floor Golden Jubilee Wing Denmark ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5516715 Thu, 15 Dec 2011 16:50:09 +0100 5516715 http://www.medworm.com/index.php?rid=5516716&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqj25210367203uk8%2F In conclusion, this study confirms that varicella-related hospitalizations are not uncommon in children, and two thirds of these children are otherwise healthy. The annual cost of hospitalization for varicella reflects only a small part of the overall cost of this disease, as only a very few cases require hospital admission. The incidence of this disease was higher in children <1 year of age, and there are no prevention strategies for these children other than population-wide vaccination. Universal vaccination is therefore the only realistic option for the prevention of severe complications and deaths. The surveillance of varicella-associated complications is essential for monitoring of the impact of varicella immunization. Content Type Journal ArticleCategory Original Ar... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5516716 Thu, 15 Dec 2011 06:44:41 +0100 5516716 http://www.medworm.com/index.php?rid=5516717&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr671407353271507%2F This study revealed the dynamic development of pediatric HEN services in Poland but also documented their potential regional shortages. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00431-011-1646-8Authors Agnieszka Szlagatys-Sidorkiewicz, Department of Pediatrics, Gastroenterology, Hepatology and Nutrition, Medical University of Gdansk, ul. Nowe Ogrody 1-6, 80-03 Gdansk, PolandKatarzyna Popińska, Department of Pediatrics, The Children’s Memorial Health Institute, Warsaw, PolandEwa Toporowska-Kowalska, Department of Allergology, Gastroenterology and Nutrition, Medical University of Lodz, Lodz, PolandAnna Borkowska, Department of Pediatrics, Gastroenterology, Hepatology and Nutrition, Medical University of Gdansk, ul. Nowe Ogrody 1-6, 80-03 Gdansk, Po... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5516717 Wed, 14 Dec 2011 16:40:26 +0100 5516717 http://www.medworm.com/index.php?rid=5516718&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj10k21x767277v78%2F Abstract  On routine neonatal examination, a newborn term male was noted to have unilateral enlargement of the right lower limb, loose thickened red skin over the palm and widening of all the fingers on the right hand. His body was pinker and warmer on the right side compared with the left and he had a right undescended testicle and hypoplastic scrotum. Radiological examination of the lower limbs demonstrated the enlargement of the soft tissue of the right lower limb compared to the left (Fig. 1). Therefore, the diagnosis was unclear from this constellation of findings and an ophthalmic assessment was requested. Content Type Journal ArticleCategory Your DiagnosisPages 1-2DOI 10.1007/s00431-011-1642-zAuthors Shanel Sharma, Paediatrics and Strabismus Service, Moorfields E... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5516718 Tue, 13 Dec 2011 06:58:01 +0100 5516718 http://www.medworm.com/index.php?rid=5507358&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx5rv85236g55w781%2F Abstract  Four children under 16 months of age presented within an 18-month period with severe, rapidly progressive Panton–Valentine leukocidin-associated ST93 Staphylococcus aureus necrotizing pneumonia. Two of the cases that required extracorporeal membranous oxygenation and proved fatal had poor prognostic features of leukopaenia, rash and pulmonary haemorrhage. All four cases had recent contact with S. aureus infection in a family member. Reported cases of S. aureus necrotizing pneumonia in infants are reviewed, and approach to management is discussed. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-011-1651-yAuthors Kevin L. Schwartz, The Hospital for Sick Children, 555 University Ave, Toronto, ON, Canada M5G 1X8Clare Nourse, ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5507358 Mon, 12 Dec 2011 17:12:11 +0100 5507358 http://www.medworm.com/index.php?rid=5507357&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnt8h806864ukp712%2F In conclusion, low VO2PEAK is associated with an elevated composite risk factor score for CVD in both young boys and girls. Content Type Journal ArticleCategory Original articlePages 1-6DOI 10.1007/s00431-011-1617-0Authors Magnus Dencker, Department of Clinical Sciences, Malmö, Unit of Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Lund University, 205 02 Malmö, SwedenOla Thorsson, Department of Clinical Sciences, Malmö, Unit of Clinical Physiology and Nuclear Medicine, Skåne University Hospital, Lund University, 205 02 Malmö, SwedenMagnus K. Karlsson, Department of Clinical Sciences and Orthopaedics, Clinical and Molecular Osteoporosis Research Unit, Skåne University Hospital, Lund University, Malmö, SwedenChristian Lindén, Department of Clinical Scie... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5507357 Mon, 12 Dec 2011 17:12:11 +0100 5507357 http://www.medworm.com/index.php?rid=5496868&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1618203011983qh3%2F Conclusion The higher prevalence of CALs in incomplete KD reflects difficulties in diagnosis and delays in treatment. More timely diagnosis and treatment of incomplete KD patients could further prevent the development of cardiac lesions. Content Type Journal ArticleCategory Original articlePages 1-6DOI 10.1007/s00431-011-1630-3Authors Daisuke Sudo, Department of Public Health, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, JapanYoshiro Monobe, Department of Public Health, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, JapanMayumi Yashiro, Department of Public Health, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi 329-0498, JapanMakiko Naka Mieno, Department of Medical Informatics, Jichi Medical University, Shimo... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5496868 Fri, 09 Dec 2011 17:06:00 +0100 5496868 http://www.medworm.com/index.php?rid=5496867&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr81247hn88pj6562%2F In conclusion, parents should be aware of the role of honey as a source of spores of Clostridium botulinum and therefore infant botulism in the first year of life. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00431-011-1649-5Authors Gautier Hoarau, Department of Clinical Microbiology, CHU Grenoble, Grenoble, 38043 FranceIsabelle Pelloux, Department of Clinical Microbiology, CHU Grenoble, Grenoble, 38043 FranceArmelle Gayot, Department of Paediatrics, CHU Grenoble, Grenoble, 38043 FranceIsabelle Wroblewski, Department of Paediatrics, CHU Grenoble, Grenoble, 38043 FranceMichel-Robert Popoff, National Reference Center for Anaerobic Bacteria and Botulism, Pasteur Institute, Paris, FranceChristelle Mazuet, National Reference Center for Anaerobic Bacteria and Bot... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5496867 Fri, 09 Dec 2011 17:06:00 +0100 5496867 http://www.medworm.com/index.php?rid=5496870&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm775546172200254%2F Conclusion: Gilbert genotype should be kept in the clinician’s mind, at least as a contributor factor, in cases with unexplained indirect hyperbilirubinemia. Content Type Journal ArticleCategory ReviewPages 1-5DOI 10.1007/s00431-011-1641-0Authors Andrew Fretzayas, 3rd Department of Pediatrics, “Attikon” University Hospital, Athens University, School of Medicine, 1 Rimini str, Haidari, 12462 Athens, GreeceMaria Moustaki, 3rd Department of Pediatrics, “Attikon” University Hospital, Athens University, School of Medicine, 1 Rimini str, Haidari, 12462 Athens, GreeceOlga Liapi, 3rd Department of Pediatrics, “Attikon” University Hospital, Athens University, School of Medicine, 1 Rimini str, Haidari, 12462 Athens, GreeceThemistocles Karpathios, Department of Pediatrics, Athen... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5496870 Thu, 08 Dec 2011 07:21:25 +0100 5496870 http://www.medworm.com/index.php?rid=5496869&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fen47121182612302%2F Conclusions: The prevalence of overweight and obesity is high among school children and adolescents in Tianjin. Changes in lifestyle, high socioeconomic status, parental obesity, mother’s history of gestational diabetes, and high birth weight are among the highly associated risk factors of overweight. An educational approach about maintaining a healthy weight should be introduced much earlier to high-risk children, parents, and women of childbearing age. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-011-1636-xAuthors Amanuel Kidane Andegiorgish, Epidemiology Department, College of Public Health, Tianjin Medical University, Tianjin, 300070 Tianjin Province, People’s Republic of ChinaJianhua Wang, Epidemiology Department, College of Public Hea... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5496869 Thu, 08 Dec 2011 07:21:25 +0100 5496869 http://www.medworm.com/index.php?rid=5488971&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F14177g9j48464t04%2F Conclusion: Current ventilator’s RM parameters have limited clinical use. Using optimal breaths to calculate RM parameters improves precision and discriminating power. For integration to ventilatory care, automation of this selection must be implemented first. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00431-011-1623-2Authors Vincent Rigo, Neonatology Department, University of Liège, CHU de Liège (CHR), Boulevard du Douzième de Ligne, 1, B4000 Liège, BelgiumEstelle Graas, Nomics, Liège, BelgiumJacques Rigo, Neonatology Department, University of Liège, CHU de Liège (CHR), Boulevard du Douzième de Ligne, 1, B4000 Liège, Belgium Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal o... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5488971 Mon, 05 Dec 2011 06:33:17 +0100 5488971 http://www.medworm.com/index.php?rid=5470587&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb4r758tpt54u23g2%2F Conclusion: Complete and incomplete KD appear to be different sides of the same coin, differing only in the number of signs and symptoms at presentation. Similar laboratory findings and coronary artery outcomes between the two groups support this conclusion. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00431-011-1631-2Authors Cedric Manlhiot, Labatt Family Heart Centre, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8Erin Christie, Division of Rheumatology, Department of Pediatrics, University of Toronto, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8Brian W. McCrindle, Labatt Family Heart Centre, Department of Pediatrics, Un... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5470587 Fri, 02 Dec 2011 06:48:16 +0100 5470587 http://www.medworm.com/index.php?rid=5470589&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F462t3760mk825u50%2F Conclusion Our findings confirm that despite the benefits of antenatal antibiotics, this treatment can increase the risk of antibiotic-resistant cases of LONI. National and international surveillance of LONI epidemiology is essential to assess benefits and potential negative consequences of perinatal antibiotic exposure. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00431-011-1639-7Authors Capucine Didier, Service de Pédiatrie 2, Hôpital de Hautepierre, Centre Hospitalier Universitaire de Strasbourg, Strasbourg, FranceMarie-Pierre Streicher, Service de Pédiatrie, Centre Hospitalier de Haguenau, Haguenau, FranceDidier Chognot, Service de Pédiatrie, Hôpital le Parc, Centre Hospitalier de Colmar, Colmar, FranceRaphaèle Campagni, Service de Pédiatri... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5470589 Thu, 01 Dec 2011 19:29:38 +0100 5470589 http://www.medworm.com/index.php?rid=5470588&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc484848q8563711n%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1637-9Authors Şinasi Özsoylu, Ankara, Turkey Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5470588 Thu, 01 Dec 2011 19:29:38 +0100 5470588 http://www.medworm.com/index.php?rid=5470590&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F51v0488387187167%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1638-8Authors Christine Quentin, Department of Hematology–Oncology, Queen Fabiola Children’s Hospital, Avenue J. J. Crocq 15, 1020 Brussels, Belgium Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5470590 Wed, 30 Nov 2011 04:56:22 +0100 5470590 http://www.medworm.com/index.php?rid=5470591&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh1224084x4m3086k%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1627-yAuthors David Taylor, Paediatric Ophthalmology, University College London, 11-43 Bath Street, London, EC1V 9EL UK Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5470591 Tue, 29 Nov 2011 22:19:13 +0100 5470591 http://www.medworm.com/index.php?rid=5460522&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm374r341723k1j05%2F Conclusions We conclude that melatonin does not alter the quality of sleep EEG studies in children with epilepsy or suspected epilepsy. Melatonin does not increase the rate of successfully performed EEG studies in sleep-deprived children. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00431-011-1640-1Authors Julia Sander, Neuropediatrics, Department of Pediatrics and Neonatology, University Hospital of Saarland, Building 9, Kirrbergerstr., 66421 Homburg, Saar, GermanyMohammed Ghiath Shamdeen, Neuropediatrics, Department of Pediatrics and Neonatology, University Hospital of Saarland, Building 9, Kirrbergerstr., 66421 Homburg, Saar, GermanySven Gottschling, Department of Pediatrics, University Hospital of Saarland, Homburg, Saar, GermanyLudwig Gortner, Neu... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5460522 Mon, 28 Nov 2011 16:57:40 +0100 5460522 http://www.medworm.com/index.php?rid=5460521&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6u2772186r2276gj%2F Conclusion: Media use can have immediate and enduring fear effects that affect many children and that are far from trivial. Content Type Journal ArticleCategory ReviewPages 1-4DOI 10.1007/s00431-011-1632-1Authors Kathleen Custers, Leuven School for Mass Communication Research, Katholieke Universiteit Leuven, Parkstraat 45, Box 3603, 3000 Leuven, BelgiumJan Van den Bulck, Leuven School for Mass Communication Research, Katholieke Universiteit Leuven, Parkstraat 45, Box 3603, 3000 Leuven, Belgium Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5460521 Mon, 28 Nov 2011 16:57:40 +0100 5460521 http://www.medworm.com/index.php?rid=5460520&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe3768623772u7641%2F We present a case of intussusception in an extremely premature infant following bacterial sepsis, in which necrotizing enterocolitis was initially suspected. The correct diagnosis was made at 35 days old using abdominal ultrasonography, but the general condition of the infant had deteriorated to the point where surgery could not be performed. The patient died of multiple organ failure, and autopsy revealed ileo-ileal intussusception without a recognizable anatomical leading point. Possible mechanisms for this rare clinical entity are discussed. Content Type Journal ArticleCategory Short CommunicationPages 1-3DOI 10.1007/s00431-011-1635-yAuthors Yoshio Shima, Department of Pediatrics, Nippon Medical School, Tokyo, JapanSakae Kumasaka, Department of Pediatrics, Japanese Red C... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5460520 Mon, 28 Nov 2011 16:57:40 +0100 5460520 http://www.medworm.com/index.php?rid=5451008&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh77556p13w251653%2F Abstract  The aim of this study was to investigate age-related pharmacokinetic differences of cyclosporine (CyA) in children with nephrotic syndrome. Whole blood concentrations of CyA were monitored for a total of 96 times in 36 cases. The 25 male and 11 female patients ranged in age from 1.9 to 19.7 years with a mean age of 9.1 years. Renal biopsy showed minimal change in 33 patients and focal segmental glomerulosclerosis in three patients. CyA was orally administered in two divided doses just before meals. The doses of CyA administered were adjusted such that the target value for blood concentration at 2 h post-dose (C2) was 400–450 ng/ml. The 96 subjects were divided into three groups according to age: group I, 1–5 years (n = 30); group II... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5451008 Fri, 25 Nov 2011 06:44:39 +0100 5451008 http://www.medworm.com/index.php?rid=5451007&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F23n2093n41660wnq%2F Abstract  To determine the relationship between total serum bilirubin (TSB) during the first 2 days of life and subsequent neonatal morbidity in very low birth weight (VLBW, less than 1500 g) infants. We performed a prospective study of 582 VLBW infants born between July 1, 2005 and December 31, 2009. TSB was measured in umbilical cord blood (UCB), at 24 and 48 h after birth. Demographic and clinical characteristics of infants in hospital were recorded. The interaction between TSB variables during the first 48 h of life and subsequent neonatal morbidity were assessed in logistic regression analyses adjusted for multiple risk factors. It was found that TSB in UCB was in a negative correlation with occurrence of respiratory distress syndrome (RDS) [OR 0.62... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5451007 Fri, 25 Nov 2011 06:44:39 +0100 5451007 http://www.medworm.com/index.php?rid=5451009&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw141524j3g500551%2F Content Type Journal ArticleCategory EditorialPages 1-3DOI 10.1007/s00431-011-1629-9Authors Jonathan Forsey, Division of Cardiology, The Labatt Family Heart Center, The Hospital for Sick Children, Toronto, ON, Canada M5G 1X8Luc Mertens, Division of Cardiology, The Labatt Family Heart Center, The Hospital for Sick Children, Toronto, ON, Canada M5G 1X8 Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5451009 Thu, 24 Nov 2011 17:53:01 +0100 5451009 http://www.medworm.com/index.php?rid=5451010&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa8730m24l57uu14g%2F Abstract  Constitutional trisomy 21 inherent to Down syndrome (DS) is associated with several hematological disorders occurring at different ages. Neonates with DS may present with transient asymptomatic blood count abnormalities such as neutrophilia, thrombocytopenia and polycythemia. Within 1–2 months of life, 3–10% of DS infants develop transient myeloproliferative disease. Despite a spontaneous regression in most of the cases, TMD can be fatal or lead to the subsequent development of myeloid leukemia in 20% of DS children (DS ML). DS ML has clinical and biological features that define a unique entity with a high sensitivity to chemotherapy and a favorable outcome. Children with DS also have an increased risk of developing acute lymphoblastic leukemia (ALL) chara... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5451010 Wed, 23 Nov 2011 17:36:26 +0100 5451010 http://www.medworm.com/index.php?rid=5451011&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq825tj6p41735341%2F Abstract  It is the pediatrician’s role to promote the child’s well-being and to help parents raise healthy, well-adjusted children. Today’s pediatricians are confronted with a patient population in which there is a high prevalence of child abuse in its different presentations (physical, sexual, and psychological abuse and/or neglect). The immediate and long-term consequences of child abuse often are lifelong and even life-threatening in its most dramatic presentation. Unfortunately, detection of child abuse remains a difficult challenge for many physicians but also for the “well-trained” pediatrician, leaving many abused children unreported. This paper addresses the important role pediatricians can play in the detection, diagnosis, and prevention of child maltrea... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5451011 Tue, 22 Nov 2011 06:57:29 +0100 5451011 http://www.medworm.com/index.php?rid=5443624&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl5013r353p245071%2F Conclusions  Restriction of the dose of IVLE to 1 g kg−1 day−1 in preterm infants with BSI is associated with earlier negative blood cultures and reduced duration of antibiotic therapy but was associated with a lower daily weight increments. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1619-yAuthors Basma Shouman, Neonatal Intensive Care Unit, Mansoura University Children’s Hospital, Mansoura, EgyptHesham Abdel-Hady, Neonatal Intensive Care Unit, Mansoura University Children’s Hospital, Mansoura, EgyptRawia I. Badr, Department of Medical Microbiology and Immunology, Mansoura Faculty of Medicine, Mansoura, EgyptEnas Hammad, Department of Medical Microbiology and Immunology, Mansoura Faculty of Medicine, Manso... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5443624 Mon, 21 Nov 2011 18:05:57 +0100 5443624 http://www.medworm.com/index.php?rid=5443625&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu4t2u78q271j3478%2F In conclusion, NLE may be complicated with sigmoidal telangiectasia with rectal bleeding and painful plantar atrophy. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00431-011-1618-zAuthors Rasa Laurinaviciene, Department of Dermatology and Allergy Centre, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense, DenmarkHenrik Thybo Christesen, Department of Pediatrics, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense, DenmarkAnette Bygum, Department of Dermatology and Allergy Centre, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense, Denmark Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5443625 Mon, 21 Nov 2011 18:05:55 +0100 5443625 http://www.medworm.com/index.php?rid=5443626&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk782382324581l4g%2F Conclusion: 89% of patients with infantile hydrocele will have a spontaneous resolution owing to the ongoing changes in the patent processus vaginalis. Surgical intervention in the first year of life is only required for those who have an associated inguinal hernia and for those with hydroceles that become huge in size. Content Type Journal ArticleCategory Original PaperPages 1-4DOI 10.1007/s00431-011-1628-xAuthors Hussein Naji, Department of Pediatric Surgery, Astrid Lindgren Children’s Hospital, Karolinska University Hospital, SE-171 76 Stockholm, SwedenIngimar Ingolfsson, Department of Pediatric Surgery, Astrid Lindgren Children’s Hospital, Karolinska University Hospital, SE-171 76 Stockholm, SwedenDaniel Isacson, Department of Pediatric Surgery, Astrid Lindgren Children�... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5443626 Mon, 21 Nov 2011 18:05:54 +0100 5443626 http://www.medworm.com/index.php?rid=5443627&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0479045264824x44%2F Conclusion. These findings show that EV meningitis occurs in the absence of CSF pleocytosis, particularly in young infants, meaning that EV meningitis in this age group cannot be solely excluded by the absence of CSF pleocytosis. They also confirm the importance of genome detection in the diagnosis of EV meningitis in young infants. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1626-zAuthors Stephanie C. M. de Crom, Department of Pediatrics, St. Elisabeth Hospital, Hilvarenbeekseweg 60, 5022 LC Tilburg, The NetherlandsMarceline A. M. van Furth, Department of Pediatric Infectious Disease, Immunology and Rheumatology, VU Medical Centre, Amsterdam, The NetherlandsMarcel F. Peeters, Laboratory of Medical Microbiology and Immunology, St. Elisabeth H... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5443627 Mon, 21 Nov 2011 06:32:47 +0100 5443627 http://www.medworm.com/index.php?rid=5433553&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe67r4477580rn7uh%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1625-0Authors Horace B. Gardner, 318 Oklahoma Road, Manitou Springs, CO, USA Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5433553 Fri, 18 Nov 2011 07:01:23 +0100 5433553 http://www.medworm.com/index.php?rid=5411672&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm753212w29232541%2F Conclusion: There is significant phenotypic variability among patients with lipoid CAH. While splice site mutations in the StAR gene lead to premature translational termination, resulting in truncated and non-functional proteins, there is phenotypic variability among patients with such mutations. Our patient appears to have the more atypical phenotype compared to reported patients with similar mutations. The molecular mechanism underlying this heterogeneity remains unclear. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00431-011-1620-5Authors Oksana Lekarev, Department of Pediatrics, Mount Sinai School of Medicine, Box 1198, One Gustave L. Levy Place, New York, NY 10029, USADelphine Mallet, Molecular Endocrinology and Rare Diseases, Hospices Civils de Ly... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5411672 Mon, 14 Nov 2011 16:53:27 +0100 5411672 http://www.medworm.com/index.php?rid=5411673&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F48v3967765328v0p%2F Conclusions: For patients with TOF-PA, CT could accurately delineate pulmonary arterial morphology with the same level of accuracy as cardiac catheterization. Therefore, CT can be considered a reasonable diagnostic alternative for such patients. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00431-011-1621-4Authors Ming-Tai Lin, Department of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanJou-Kou Wang, Department of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanYih-Sharng Chen, College of Medicine, National Taiwan University, Taipei, TaiwanWen-Jeng Lee, College of Medicine, National Taiwan University, Taipei, TaiwanHsin-Hui Chiu, Department of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanChun-An Chen, Depa... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5411673 Mon, 14 Nov 2011 16:53:24 +0100 5411673 http://www.medworm.com/index.php?rid=5411674&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw7690l1wt1966172%2F Abstract  Retinal dystrophies are inherited disorders of photoreceptor and retinal pigment epithelial function that may result in severe visual impairment. Advances in molecular genetics have helped identify many of the gene defects responsible, and progress in gene transfer technology has enabled therapeutic strategies to be developed and applied. The first human clinical trials of gene therapy for RPE65 associated retinal dystrophy have shown promising initial results and have helped prepare the way for further trials of gene therapy for inherited retinal disorders. The results of these trials will provide further insight into the safety and efficacy of gene therapy for a range of currently untreatable and debilitating eye disorders. Content Type Journal ArticleCatego... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5411674 Mon, 14 Nov 2011 06:35:31 +0100 5411674 http://www.medworm.com/index.php?rid=5411676&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2606512177r6414g%2F Content Type Journal ArticleCategory CorrespondencePages 1-2DOI 10.1007/s00431-011-1594-3Authors Dan Xu, Department of Pulmonology, The Children’s Hospital of Zhejiang University School of Medicine, 57 Zhugan Xiang, Hangzhou, 310003 Zhejiang Province, People’s Republic of ChinaShuxian Li, Department of Pulmonology, The Children’s Hospital of Zhejiang University School of Medicine, 57 Zhugan Xiang, Hangzhou, 310003 Zhejiang Province, People’s Republic of ChinaZhimin Chen, Department of Pulmonology, The Children’s Hospital of Zhejiang University School of Medicine, 57 Zhugan Xiang, Hangzhou, 310003 Zhejiang Province, People’s Republic of ChinaLizhong Du, Department of Neonatology, The Children’s Hospital of Zhejiang University School of Medicine, 57 Zhugan Xiang, Hangzhou, ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5411676 Fri, 11 Nov 2011 12:48:07 +0100 5411676 http://www.medworm.com/index.php?rid=5411677&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe85rqu1867h3rv35%2F Conclusion: Urachal cysts may cause abdominal complaints when infected. Although rare, they should be added to the differential diagnosis of acute abdominal pain in the paediatric patient, as this case illustrates. Content Type Journal ArticleCategory Case ReportPages 1-2DOI 10.1007/s00431-011-1622-3Authors Victoria A. Janes, Department of Paediatrics, Meander Medical Centre, Postbus 1502, 3800 BM Amersfoort, The NetherlandsPaul H. G. Hogeman, Department of Paediatrics, Meander Medical Centre, Postbus 1502, 3800 BM Amersfoort, The NetherlandsNiek B. Achten, Department of Paediatric Surgery, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The NetherlandsStefaan H. A. J. Tytgat, Department of Paediatric Surgery, Wilhelmina Children’s Hospital, Universi... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5411677 Fri, 11 Nov 2011 06:55:57 +0100 5411677 http://www.medworm.com/index.php?rid=5411678&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc1123g8188551775%2F Conclusions: Physical findings rarely provide conclusive evidence of sexual abuse in isolation but may offer important pieces of the diagnostic “jigsaw picture”. Content Type Journal ArticleCategory ReviewPages 1-5DOI 10.1007/s00431-011-1556-9Authors Christopher J. Hobbs, St James’s University Hospital, Beckett Street, Leeds, LS9 7TF UK Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5411678 Wed, 09 Nov 2011 07:06:19 +0100 5411678 http://www.medworm.com/index.php?rid=5391096&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Flv652210q3765h3l%2F Conclusion. Corticosteroid combined with IVIG in primary treatment or as treatment of IVIG-resistant patients improved clinical course without increasing coronary artery lesions in children with acute KD. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00431-011-1585-4Authors Bo-hui Zhu, Department of Pediatric Cardiology, Children’s Hospital of Soochow University, 303 Jingde Road, Suzhou, 215003 ChinaHai-tao Lv, Department of Pediatric Cardiology, Children’s Hospital of Soochow University, 303 Jingde Road, Suzhou, 215003 ChinaLing Sun, Department of Pediatric Cardiology, Children’s Hospital of Soochow University, 303 Jingde Road, Suzhou, 215003 ChinaJian-min Zhang, Department of Pediatric Cardiology, Children’s Hospital of Soochow University, 303 J... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5391096 Sat, 05 Nov 2011 15:44:53 +0100 5391096 http://www.medworm.com/index.php?rid=5391097&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn136782567552705%2F Conclusion: Retinopathy of prematurity is an important cause of ocular morbidity and blindness in children. With better understanding of the pathogenesis, screening and treatment guidelines have changed over time and are unit specific. Content Type Journal ArticleCategory ReviewPages 1-7DOI 10.1007/s00431-011-1610-7Authors Ingele Casteels, Department of Ophthalmology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, BelgiumCatherine Cassiman, Department of Ophthalmology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, BelgiumJoachim Van Calster, Department of Ophthalmology, University Hospitals Leuven, Herestraat 49, 3000 Leuven, BelgiumKarel Allegaert, Neonatal Intensive Care, University Hospitals Leuven, Leuven, Belgium Journal European Journal of Pediatri... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5391097 Thu, 03 Nov 2011 16:57:26 +0100 5391097 http://www.medworm.com/index.php?rid=5391098&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy283247h51t50084%2F In conclusion, the impact of UTI on formation of USF may be enhanced by the presence of VUR with shorter duration of TDT. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1614-3Authors Mi Mi Oh, Department of Urology, College of Medicine, Korea University, Seoul, South KoreaJin Wook Kim, Department of Urology, College of Medicine, Korea University, Seoul, South KoreaMin Gu Park, Department of Urology, College of Medicine, Inje University, Busan, KoreaJe Jong Kim, Department of Urology, College of Medicine, Korea University, Seoul, South KoreaKee Hwan Yoo, Department of Pediatrics, College of Medicine, Korea University, Seoul, South KoreaDu Geon Moon, Department of Urology, College of Medicine, Korea University, Seoul, South Korea Journal Eur... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5391098 Wed, 02 Nov 2011 16:58:54 +0100 5391098 http://www.medworm.com/index.php?rid=5367381&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk715xh2375117t0h%2F In conclusion, ciliated cells with loss of cilia, cytoplasmic blebbing, and ambiguity of the “9 + 2” microtubule array were the most commonly encountered abnormal findings in MPP. Multiple abnormalities, especially those associated with central complex defects, may indicate an unfavorable prognosis. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00431-011-1609-0Authors Hui Liang, Department of Respiratory Medicine, The Affiliated Nanjing Children’s Hospital of Nanjing Medical University, No. 72 Guangzhou Road, Nanjing, 210008 ChinaWujun Jiang, Department of Respiratory Medicine, The Affiliated Nanjing Children’s Hospital of Nanjing Medical University, No. 72 Guangzhou Road, Nanjing, 210008 ChinaQing Han, Department of Respiratory Medicine, The... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5367381 Fri, 28 Oct 2011 17:13:34 +0100 5367381 http://www.medworm.com/index.php?rid=5367383&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa68r71243380826g%2F Conclusion: The decision to initiate ERT in severe Hunter syndrome should be made by the physician and parents and must be based on realistic expectations of benefits and risks, with the understanding that ERT may be withdrawn in the absence of demonstrable benefits. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00431-011-1606-3Authors Joseph Muenzer, Department of Pediatrics, CB 7487, Medical School Wing E Room 117, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7487, USAOlaf Bodamer, Division of Clinical and Translational Genetics, University of Miami Miller School of Medicine, Miami, FL, USABarbara Burton, Children’s Memorial Hospital and Northwestern University Feinberg School of Medicine, Chicago, IL, USALorne Clarke, Departmen... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5367383 Fri, 28 Oct 2011 17:13:31 +0100 5367383 http://www.medworm.com/index.php?rid=5367382&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftw8083865792t37q%2F Content Type Journal ArticleCategory CorrespondencePages 1-2DOI 10.1007/s00431-011-1602-7Authors Se Jin Park, Department of Pediatrics, Ajou University School of Medicine, Ajou University Hospital, Suwon, South KoreaKi Soo Pai, Department of Pediatrics, Ajou University School of Medicine, Ajou University Hospital, Suwon, South KoreaJi Hong Kim, The Institute of Kidney Disease, Department of Pediatrics, Yonsei University College of Medicine, Severance Children’s Hospital, 50 Yonsei-ro, Seodaemun-gu, C.P.O. Box 8044, Seoul, 120-752 South KoreaJae Il Shin, The Institute of Kidney Disease, Department of Pediatrics, Yonsei University College of Medicine, Severance Children’s Hospital, 50 Yonsei-ro, Seodaemun-gu, C.P.O. Box 8044, Seoul, 120-752 South Korea Journal European Journal... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5367382 Fri, 28 Oct 2011 17:13:31 +0100 5367382 http://www.medworm.com/index.php?rid=5367384&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc2672057u70p4637%2F Conclusion: AHT should be approached with a structured approach, as in any other (potentially lethal) disease. The clinician can only establish this diagnosis if he/she has knowledge of the signs and symptoms of AHT, risk factors, the differential diagnosis and which additional investigations to perform, the more so since parents seldom will describe the true state of affairs spontaneously. Content Type Journal ArticleCategory ReviewPages 1-9DOI 10.1007/s00431-011-1598-zAuthors Tessa Sieswerda-Hoogendoorn, Section Forensic Paediatrics, Department of Forensic Medicine, Netherlands Forensic Institute, The Hague, The NetherlandsStephen Boos, Department of Pediatrics, Baystate Children’s Hospital, Springfield, MA, USABetty Spivack, Consulting child abuse paediatrician in Buffalo, Ne... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5367384 Thu, 27 Oct 2011 15:45:49 +0100 5367384 http://www.medworm.com/index.php?rid=5350454&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frm664t7316407524%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1612-5Authors Maria Dorota Majewska, Department of Pharmacology, Institute of Psychiatry and Neurology, 9 Sobieskiego St., 02-957 Warsaw, PolandJosé G. Dórea, C.P. 04322, Faculty of Health Sciences, Universidade de Brasilia, 70919-970 Brasilia, Brazilian Federal District, Brazil Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5350454 Fri, 21 Oct 2011 15:59:50 +0100 5350454 http://www.medworm.com/index.php?rid=5350453&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj56k38p41gl3w720%2F Conclusion: Adverse event registration in general pediatric practice is a first step in assessing quality and safety of care. It yields a considerable number of adverse events. Compliance to adverse event registration in daily practice is difficult but also key to optimal monitoring of quality of care. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1608-1Authors Cynthia van der Starre, Intensive Care, Department of Pediatric Surgery, Erasmus MC-Sophia, Rotterdam, The NetherlandsMonique van Dijk, Intensive Care, Department of Pediatric Surgery, Erasmus MC-Sophia, Rotterdam, The NetherlandsDick Tibboel, Intensive Care, Department of Pediatric Surgery, Erasmus MC-Sophia, Rotterdam, The Netherlands Journal European Journal of PediatricsOnline... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5350453 Fri, 21 Oct 2011 15:59:50 +0100 5350453 http://www.medworm.com/index.php?rid=5350455&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr75v234724052340%2F Abstract  The impact of behavior problems on kindergarten readiness is not known. Our objective was to estimate the association between behavior problems and kindergarten readiness on a US national sample. In the US educational system, kindergarten is a natural point of entry into formal schooling at age 5 because fewer than half of the children enter kindergarten with prior formal preschool education. Parents of 1,200 children who were scheduled to enter kindergarten for the first time and were members of the Harris Interactive online national panel were surveyed. We defined behavior problems as an affirmative response to the question, “Has your child ever had behavior problems?” We validated this against attention deficit hyperactivity disorder diagnosis, scores on a ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5350455 Thu, 20 Oct 2011 15:52:23 +0100 5350455 http://www.medworm.com/index.php?rid=5350456&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh55rj632v2q117n7%2F Conclusion: A national program is needed in Turkey for SMA prevention and creation of expert teams for the management of these patients. Content Type Journal ArticleCategory Original PaperPages 1-4DOI 10.1007/s00431-011-1607-2Authors Barış Ekici, Department of Pediatric Neurology, Istanbul Medical Faculty, Ortaköy Dereboyu cad. Arkeon sitesi A 5 blok D 3, Beşiktaş, Fatih, Istanbul, TurkeyBetül Bozkurt, Department of Family Medicine, Istanbul Medical Faculty, Istanbul, TurkeyBurak Tatlı, Department of Pediatric Neurology, Istanbul Medical Faculty, Ortaköy Dereboyu cad. Arkeon sitesi A 5 blok D 3, Beşiktaş, Fatih, Istanbul, TurkeyMine Çalışkan, Department of Pediatric Neurology, Istanbul Medical Faculty, Ortaköy Dereboyu cad. Arkeon sitesi A 5 blok D 3, Beşiktaş, Fatih... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5350456 Thu, 20 Oct 2011 15:52:22 +0100 5350456 http://www.medworm.com/index.php?rid=5350458&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg4rx3327314101j7%2F Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s00431-011-1601-8Authors Isabelle Rochat, Pediatric Pulmonology Unit, Children’s Hospital, University Hospitals, Geneva, SwitzerlandPatricia Leis, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandMarie Bouchardy, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandChristine Oberli, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandHendrika Sourial, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandMargrit Friedli-Burri, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandThomas Perneger, Division of Clinical Epidemiology, Universit... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5350458 Thu, 20 Oct 2011 05:56:20 +0100 5350458 http://www.medworm.com/index.php?rid=5350457&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F11m7788g12436j81%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1613-4Authors Wieslaw Jedrychowski, Jagiellonian University, Krakow, Poland Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5350457 Thu, 20 Oct 2011 05:56:20 +0100 5350457 http://www.medworm.com/index.php?rid=5338873&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx2218357548032n1%2F Conclusion: We consider that general anaesthesia increases effective reduction pressures and could avoid many surgeries in apparently non-reducible intestinal intussusceptions. Content Type Journal ArticleCategory Short CommunicationPages 1-3DOI 10.1007/s00431-011-1604-5Authors Raquel Diaz-Aldagalán González, Pediatrics, Complejo Hospitalario de Navarra, C/Irunlarrea 4, 31008 Pamplona, Navarra, SpainAlberto Pérez-Martínez, Pediatric Surgery, Complejo Hospitalario de Navarra, C/Irunlarrea 4, 31008 Pamplona, Navarra, SpainJavier Pisón-Chacón, Pediatric Surgery, Complejo Hospitalario de Navarra, C/Irunlarrea 4, 31008 Pamplona, Navarra, SpainLidia Ayuso-González, Pediatric Surgery, Complejo Hospitalario de Navarra, C/Irunlarrea 4, 31008 Pamplona, Navarra, SpainBlanca Salcedo-Mu�... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5338873 Wed, 19 Oct 2011 15:52:47 +0100 5338873 http://www.medworm.com/index.php?rid=5338874&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl1x0x2480g05t464%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1603-6Authors Farah Thabet, Riyad Military Hospital, Riyad, Saudi Arabia Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5338874 Tue, 18 Oct 2011 15:59:19 +0100 5338874 http://www.medworm.com/index.php?rid=5338875&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk6211167j6780130%2F Conclusion Anemia, particularly iron deficiency anemia and anemia of inflammation, is highly prevalent among children with HIV infection. Micronutrient supplements combined with ART improved anemia in HIV-infected children. Content Type Journal ArticleCategory Original PaperPages 1-10DOI 10.1007/s00431-011-1599-yAuthors Anita Shet, Department of Pediatrics, St. John’s National Academy of Health Sciences, Sarjapur Road, Bangalore, 560034 IndiaKarthika Arumugam, Division of Biostatistics, St. John’s National Academy of Health Sciences, Bangalore, IndiaNirmala Rajagopalan, Freedom Foundation, Bangalore, IndiaChitra Dinakar, Department of Pediatrics, St. John’s National Academy of Health Sciences, Sarjapur Road, Bangalore, 560034 IndiaShubha Krishnamurthy, Infectious Diseases Cli... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5338875 Tue, 18 Oct 2011 15:59:17 +0100 5338875 http://www.medworm.com/index.php?rid=5325995&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl17048j638672536%2F In conclusion, these children require clinical evaluation similar to that performed in female children with TS, including cardiovascular, renal, endocrine, growth and development, autoimmune, psychological, and educational evaluation. Specific management needs to be tailored to the presence of Y chromosomal material. Content Type Journal ArticleCategory Original PaperPages 1-9DOI 10.1007/s00431-011-1600-9Authors Hanan Tosson, Pediatric Endocrinology Clinic, Morgantown, WV, USASusan R. Rose, Division of Pediatric Endocrinology, Department of Pediatrics, Cincinnati Children’s Hospital Medical Center and University of Cincinnati, Cincinnati, OH, USALou Ann Gartner, Division of Pediatric Endocrinology, Department of Pediatrics, Women’s and Children’s Hospital of Buffalo and Stat... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5325995 Thu, 13 Oct 2011 15:48:39 +0100 5325995 http://www.medworm.com/index.php?rid=5317451&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb25j462p41636466%2F In conclusion, bacterial resistance could be reduced by the implementation of systemic and long-term measures at a country level as well as at all levels of healthcare. In order to reduce bacterial resistance, antibiotic use needs to be precisely regulated, and regulations should be coherent with practice. The international community must have a more active role in solving this global problem. Content Type Journal ArticleCategory ReviewPages 1-11DOI 10.1007/s00431-011-1592-5Authors Katarina Ilić, Department of Pharmacology, School of Pharmacy, University of Belgrade, PO BOX 146, Vojvode Stepe 450, 11221 Belgrade, Republic of SerbiaEmil Jakovljević, Department of Pharmacology, School of Pharmacy, University of Belgrade, PO BOX 146, Vojvode Stepe 450, 11221 Belgrade, Republic of ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5317451 Mon, 10 Oct 2011 15:06:39 +0100 5317451 http://www.medworm.com/index.php?rid=5317450&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fumv340641261q035%2F Conclusion: The clinical courses of Barth syndrome observed in our cases show the phonotypic variability of this syndrome and suggest that early therapy may be beneficial for maintaining cardiac function. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1597-0Authors Nobuo Momoi, Department of Pediatrics, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960-1295 JapanBo Chang, Department of Pediatrics, Toyama University, 2630 Sugitani, Toyama, 930-0194 JapanIzumi Takeda, Department of Pediatrics, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960-1295 JapanYoshimichi Aoyagi, Department of Pediatrics, Fukushima Medical University School of Medicine, 1 Hikarigaoka, Fukushima, 960-1295 JapanKisei E... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5317450 Mon, 10 Oct 2011 15:06:39 +0100 5317450 http://www.medworm.com/index.php?rid=5306640&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F45183u12r24w8834%2F Conclusion: Although IPEX syndrome is usually a disease of infancy, it should not be ruled out solely on the basis of age. IPEX presentation is so variable that it should be suspected in a male child with one or more autoimmune disorders and severe infections. Content Type Journal ArticleCategory Short ReportPages 1-5DOI 10.1007/s00431-011-1588-1Authors Keun Wook Bae, Department of Pediatrics, Asan Medical Center Children’s Hospital, University of Ulsan College of Medicine, Seoul, South KoreaBo Eun Kim, Department of Pediatrics, Asan Medical Center Children’s Hospital, University of Ulsan College of Medicine, Seoul, South KoreaJin-Ho Choi, Department of Pediatrics, Asan Medical Center Children’s Hospital, University of Ulsan College of Medicine, Seoul, South KoreaJoo Hoon Le... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5306640 Fri, 07 Oct 2011 05:45:47 +0100 5306640 http://www.medworm.com/index.php?rid=5306641&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft8313h33w0336517%2F Abstract  Low back pain (LBP) is prevalent in teenagers but not necessarily detrimental to their quality of life (QoL). This population-based study evaluated a global QoL score and the association between LBP and life events and/or health problems affecting QoL. Schoolchildren were investigated in Fribourg-Switzerland and Barcelona-Spain. In addition to the KIDSCREEN, a health-related QoL questionnaire, two Numerical Rating Scales were used to assess QoL in general, and the influence of LBP on QoL. Open questions explored life events and health problems affecting QoL; responses were submitted to content analysis. Adolescents were stratified: Pain-free, Other pain (OP), isolated LBP (IsoLBP), LBP + other pains (LBP + OP), and LBP + whole-body pain (LBP + WBP). Between-group ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5306641 Fri, 07 Oct 2011 05:45:44 +0100 5306641 http://www.medworm.com/index.php?rid=5306642&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft570796751260887%2F Conclusion: The data presented provide information for abdominal risk assessment and clinical and lifestyle intervention; our results also provide useful baseline data information for the implementation of a surveillance system required to monitor trends and factors associated with abdominal obesity in children and adolescents. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00431-011-1595-2Authors Luís B. Sardinha, Exercise and Health Laboratory, Faculty of Human Movement, Technical University of Lisbon, Lisbon, PortugalRute Santos, Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Rua Dr. Plácido Costa, 91, 4200-450 Porto, PortugalSusana Vale, Research Centre in Physical Activity, Health and Leisure, Facul... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5306642 Thu, 06 Oct 2011 15:41:39 +0100 5306642 http://www.medworm.com/index.php?rid=5306643&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ferlvrm35mh411w86%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1583-6Authors Susan Farmand, Freiburg, GermanyStefan Wirth, Wuppertal, GermanyPhilipp Henneke, Freiburg, Germany Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5306643 Thu, 06 Oct 2011 05:48:27 +0100 5306643 http://www.medworm.com/index.php?rid=5298524&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu2242601253g484k%2F Content Type Journal ArticleCategory CorrespondencePages 1-2DOI 10.1007/s00431-011-1590-7Authors Jessica Maltha, Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, BelgiumJan Jacobs, Department of Clinical Sciences, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5298524 Wed, 05 Oct 2011 05:45:44 +0100 5298524 http://www.medworm.com/index.php?rid=5298525&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx58m64651q63h282%2F Content Type Journal ArticleCategory CorrespondencePages 1-2DOI 10.1007/s00431-011-1589-0Authors G. P. Prashanth, Department of Pediatrics, KLE University’s JN Medical College, Nehru Nagar, Belgaum, 590010 Karnataka, India Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5298525 Tue, 04 Oct 2011 05:49:59 +0100 5298525 http://www.medworm.com/index.php?rid=5298526&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe81876174p116211%2F In conclusion, overweight children with T1DM have a more favourable lipid profile, as compared to non-diabetic overweight controls, in spite of a higher frequency of a positive family history of CVD, T2DM and hypertension. Still, paediatricians should give extra attention to cardiometabolic risk factors within this vulnerable group, taking into account the already high cardiometabolic risk. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1574-7Authors Mariska van Vliet, Department of Pediatrics, Slotervaart Hospital, Louwesweg 6, 1066 EC Amsterdam, The NetherlandsJosine C. van der Heyden, Diabeter, Haringvliet 72, 3011 TG Rotterdam, The NetherlandsMichaela Diamant, Diabetes Center/Department of Internal Medicine, VU University Medical Center, De... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5298526 Tue, 04 Oct 2011 05:49:58 +0100 5298526 http://www.medworm.com/index.php?rid=5298527&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw81491vmm6361564%2F Abstract  Retinal haemorrhages are an important component of the clinical effects of non-accidental head injuries which have significant visual morbidity. Their importance extends into the legal investigations of carers of children with subdural haemorrhages and encephalopathy who are suspected of having been non-accidentally injured. The vital precision in diagnosis relies not just on the presence of retinal haemorrhages but on the severity, extent, bilaterality and their location in the retina. Inadequate documentation of ophthalmological clinical findings and too short a follow-up to allow proper assessment of severity each give rise to difficulties for both expert witnesses and the courts. Content Type Journal ArticleCategory ReviewPages 1-3DOI 10.1007/s00431-011-15... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5298527 Tue, 04 Oct 2011 05:49:57 +0100 5298527 http://www.medworm.com/index.php?rid=5298529&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fll6r24l757627043%2F This report shows that the result of a CTT cannot be accepted blindly. Especially the clustering of many markers within narrow margins might point at entrapment of markers in mucus against the colonic wall. Content Type Journal ArticleCategory Short ReportPages 1-3DOI 10.1007/s00431-011-1593-4Authors Tim G. J. de Meij, Department of Pediatric Gastroenterology, VU University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, The NetherlandsC. M. Frank Kneepkens, Department of Pediatric Gastroenterology, VU University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5298529 Tue, 04 Oct 2011 05:49:56 +0100 5298529 http://www.medworm.com/index.php?rid=5298528&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv64w3k76q8643n84%2F Abstract  The neutrophilic granulocyte (neutrophil) is the most important cellular component of the innate immune system. A total absence of neutrophils or a significant decrease in their number leads to severe immunodeficiency. A mature neutrophil, released from the bone marrow, should be able to migrate from the blood towards the tissues, following a chemotactic gradient to a pathogen. In order to be neutralized, this pathogen has to be recognized, phagocytosed, and destroyed by lytic enzymes contained in the neutrophil's granules and reactive oxygen species formed by the enzyme complex NADPH oxidase. Rare genetic defects leading to the loss of each one of these biological properties of the neutrophil have been described and are associated with immunodeficiency. This revi... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5298528 Tue, 04 Oct 2011 05:49:56 +0100 5298528 http://www.medworm.com/index.php?rid=5288194&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft886584771772256%2F Abstract  Congenital nasal obstruction can result in neonatal respiratory distress because neonates are obligate nasal breathers. Therefore, all physicians who deal with infants should be familiar with the structural abnormalities, masses, and syndromes that cause nasal obstruction, so that appropriate work-up and treatment can be promptly initiated. This paper reviews the embryology of the nasal passage and then continues with the different causes of nasal obstruction. Special attention is paid to the presentation, physical exam findings, and imaging modality of choice. Content Type Journal ArticleCategory ReviewPages 1-10DOI 10.1007/s00431-011-1591-6Authors Eelam Adil, Division of Otolaryngology-Head and Neck Surgery, Pennsylvania State University, 500 University Dri... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5288194 Sat, 01 Oct 2011 06:44:10 +0100 5288194 http://www.medworm.com/index.php?rid=5288196&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr4g1838122444323%2F Conclusion: In young children total IgE is of limited value when evaluating allergy-related disorder. The lack of agreement among the positive tests of the sIgE and SPT for some allergens imply that these tests should not be used interchangeably, and both tests should probably be used complementarily when diagnosing atopic sensitization in small children. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1580-9Authors Anne D. Rø, Department of Immunology and Transfusion Medicine, St. Olavs Hospital, Trondheim University Hospital, Trondheim, NorwayMarit Saunes, Department of Public Health and General Practice, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, NorwayIngeborg Smidesang, Department of Pediatrics, ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5288196 Fri, 30 Sep 2011 05:52:24 +0100 5288196 http://www.medworm.com/index.php?rid=5288195&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F264wm78021638414%2F In conclusion, the findings indicate that pediatric patients with moderate-to-severe plaque psoriasis have significantly impaired generic HRQOL in comparison to healthy children, and HRQOL generally comparable to other serious chronic diseases. These results demonstrate the significant negative impact of plaque psoriasis on the daily lives of these children from the patients’ perspective. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00431-011-1587-2Authors James W. Varni, Department of Pediatrics, College of Medicine, Texas A&M University, College Station, TX, USADenise R. Globe, Amgen, Thousand Oaks, CA, USAShravanthi R. Gandra, Amgen, Thousand Oaks, CA, USADavid J. Harrison, Amgen, Thousand Oaks, CA, USAMichele Hooper, Amgen, Thousand Oaks, CA, USA... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5288195 Fri, 30 Sep 2011 05:52:24 +0100 5288195 http://www.medworm.com/index.php?rid=5288197&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc52g238082806641%2F Conclusion: Liddle syndrome should be considered as a cause of hypertension in children or adolescents particularly with suppressed renin activity. Early diagnosis and appropriately tailored treatment avoid complications of long-term unrecognized or inappropriately managed hypertension. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00431-011-1581-8Authors Radovan Bogdanović, Medical Faculty, University of Belgrade, Belgrade, SerbiaVladimir Kuburović, Institute of Mother and Child Healthcare of Serbia “Dr Vukan Čupić”, 8 Radoja Dakica Street, 11070 Belgrade, SerbiaNataša Stajić, Institute of Mother and Child Healthcare of Serbia “Dr Vukan Čupić”, 8 Radoja Dakica Street, 11070 Belgrade, SerbiaSadaf S. Mughal, Institute of Human Genetics, Un... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5288197 Thu, 29 Sep 2011 06:18:04 +0100 5288197 http://www.medworm.com/index.php?rid=5276773&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm045m153t227588w%2F We report a brain abscess caused by L. lactis cremoris in an immunocompetent child. A 19-month-old female patient was admitted with fever and vomiting. Brain computed tomography (CT) revealed brain abscess. L. lactis cremoris was isolated from culture of the abscess material. The patient was treated with pus drainage from brain abscess and antibiotics including vancomycin and meropenem. The patient recovered completely. To our knowledge, this is the first report of a L. lactis cremoris infection in children. Content Type Journal ArticleCategory Short ReportPages 1-3DOI 10.1007/s00431-011-1586-3Authors Yasemin Topçu, Department of Pediatrics, Division of Child Neurology, Dokuz Eylul University Medical Faculty, İzmir, TurkeyGülçin Akıncı, Department of Pediatrics, Division of ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5276773 Wed, 28 Sep 2011 05:51:15 +0100 5276773 http://www.medworm.com/index.php?rid=5252704&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg012706t3677735p%2F Conclusion: Further studies should be conducted to evaluate the optimal oral dosage of vitamin B12 in children since limited data on the use of oral B12 substitution are available. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00431-011-1577-4Authors Christine Quentin, Department of Hematology and Oncology, Université Libre de Bruxelles (ULB), Queen Fabiola Children’s Hospital, Avenue J. J. Crocq 15, 1020 Brussels, BelgiumSophie Huybrechts, Department of Hematology and Oncology, Université Libre de Bruxelles (ULB), Queen Fabiola Children’s Hospital, Avenue J. J. Crocq 15, 1020 Brussels, BelgiumLaurence Rozen, Laboratory of CHU-Brugmann, Université Libre de Bruxelles (ULB), Queen Fabiola Children’s Hospital, Avenue J. J. Crocq 15, 1020 Brussels, Belg... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5252704 Fri, 23 Sep 2011 15:51:08 +0100 5252704 http://www.medworm.com/index.php?rid=5252703&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq418333mh77n2478%2F We report a case of a three-and-a-half-year-old boy, who presented with poor general condition, stunted growth, had the presence of nail clubbing, persistent cough and frequent diarrhoea. Persistent iron deficiency anaemia without signs of haemolysis suggested Lane-Hamilton syndrome (LHS) which is or/is an extremely rare combination of idiopathic pulmonary haemosiderosis (IPH) and celiac disease (CD), although both diseases are immunologically mediated and the pathogenetic link between them is not clear. We have now 3 years of follow-up on gluten-free diet (GFD), resulting in a gradual recovery of the abnormal laboratory results in combination with an improving growth. Clinically, he is asymptomatic without any additional treatment. Our case illustrates that CD should be specifi... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5252703 Fri, 23 Sep 2011 15:51:08 +0100 5252703 http://www.medworm.com/index.php?rid=5252705&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc497943k4g6g7779%2F Conclusion: Awareness of the possibility of true mechanical obstruction in CIPS patients during an exacerbation episode is needed, as this is a severe condition and usually requires surgical intervention. Content Type Journal ArticleCategory Short ReportPages 1-5DOI 10.1007/s00431-011-1554-yAuthors Carlijn T. de Betue, Department of Pediatric Surgery, Emma Children’s Hospital/Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The NetherlandsDoeke Boersma, Department of Pediatric Surgery, Emma Children’s Hospital/Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The NetherlandsMatthijs W. Oomen, Department of Pediatric Surgery, Emma Children’s Hospital/Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The NetherlandsMarc A. Benninga, Department of ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5252705 Fri, 23 Sep 2011 05:45:16 +0100 5252705 http://www.medworm.com/index.php?rid=5252706&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu1652322251u8v56%2F Conclusion: physicians should be aware of the possibility of this disease and carry out genetic studies when it is considered. Content Type Journal ArticleCategory ReviewPages 1-3DOI 10.1007/s00431-011-1575-6Authors Atsuhito Takeda, Department of Pediatrics, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo, 060-8638 JapanAkira Sudo, Department of Pediatrics, Sapporo City General Hospital, 1-1, North 11, West 13, Chuo-ku, Sapporo, 060-8604 JapanMasafumi Yamada, Department of Pediatrics, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo, 060-8638 JapanHirokuni Yamazawa, Department of Pediatrics, Hokkaido University Graduate School of Medicine, North 15, West 7, Kita-ku, Sapporo, 060-8638 JapanGaku Izumi, Department o... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5252706 Fri, 23 Sep 2011 05:45:15 +0100 5252706 http://www.medworm.com/index.php?rid=5252708&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5qk7r608x2623682%2F Conclusion: Immunogenicity of the combined MMRV vaccine was sustained 3 years post-vaccination. (208136/041/NCT00406211). Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00431-011-1569-4Authors Markus Knuf, Children’s Department of Pediatrics, University Medicine Hospital, Johannes Gutenberg-University, Langenbeckstrasse 1, 55101 Mainz, GermanyFred Zepp, Children’s Department of Pediatrics, University Medicine Hospital, Johannes Gutenberg-University, Langenbeckstrasse 1, 55101 Mainz, GermanyKlaus Helm, Pediatric Office, Detmold, GermanyHartwig Maurer, Pediatric Office, Salzburg, AustriaAlbrecht Prieler, Pediatric Office, Salzburg, AustriaDorothee Kieninger-Baum, Children’s Department of Pediatrics, University Medicine Hospital, Johannes Gutenberg-... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5252708 Tue, 20 Sep 2011 15:46:10 +0100 5252708 http://www.medworm.com/index.php?rid=5252707&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F564600l47u547123%2F Content Type Journal ArticleCategory Images in PediatricsPages 1-1DOI 10.1007/s00431-011-1573-8Authors Eda Karadag Oncel, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, TurkeyMeryem Seda Boyraz, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, TurkeyAtes Kara, Department of Pediatrics, Faculty of Medicine, Hacettepe University, Ankara, Turkey Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5252707 Tue, 20 Sep 2011 15:46:10 +0100 5252707 http://www.medworm.com/index.php?rid=5241060&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm5157k72g7223t78%2F Abstract  Cerebral palsy (CP) is the most common physical disability in early childhood. The worldwide prevalence of CP is approximately 2–2.5 per 1,000 live births. It has been clinically defined as a group of motor, cognitive, and perceptive impairments secondary to a non-progressive defect or lesion of the developing brain. Children with CP can have swallowing problems with severe drooling as one of the consequences. Malnutrition and recurrent aspiration pneumonia can increase the risk of morbidity and mortality. Early attention should be given to dysphagia and excessive drooling and their substantial contribution to the burden of a child with CP and his/her family. This review displays the important functional and anatomical issues related to swallowing problems in ch... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5241060 Mon, 19 Sep 2011 15:40:17 +0100 5241060 http://www.medworm.com/index.php?rid=5241059&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F63gv52704q7502g3%2F Content Type Journal ArticleCategory CorrespondencePages 1-1DOI 10.1007/s00431-011-1582-7Authors Giuseppe Indolfi, Paediatric and Liver Unit, Meyer Children’s University Hospital of Florence, Viale Pieraccini 24, I-50139 Florence, ItalyElisa Bartolini, Paediatric and Liver Unit, Meyer Children’s University Hospital of Florence, Viale Pieraccini 24, I-50139 Florence, ItalyMassimo Resti, Paediatric and Liver Unit, Meyer Children’s University Hospital of Florence, Viale Pieraccini 24, I-50139 Florence, Italy Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5241059 Mon, 19 Sep 2011 15:40:17 +0100 5241059 http://www.medworm.com/index.php?rid=5241061&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5042t8148441j642%2F Conclusion: High-dose bisphosphonate therapy may not be necessary for an extended period of time in children with GACI. Content Type Journal ArticleCategory Short ReportPages 1-6DOI 10.1007/s00431-011-1572-9Authors Thomas Edouard, Bone Metabolism Clinic, Department of Pediatrics, Sainte-Justine University Hospital, 3175 Chemin de la Côte Sainte-Catherine, Montreal, QC H3T1C5, CanadaGilles Chabot, Bone Metabolism Clinic, Department of Pediatrics, Sainte-Justine University Hospital, 3175 Chemin de la Côte Sainte-Catherine, Montreal, QC H3T1C5, CanadaJoaquim Miro, Department of Cardiology, Sainte-Justine University Hospital, Montreal, QC, CanadaDaniela Christina Buhas, Department of Genetics, Sainte-Justine University Hospital, Montreal, QC, CanadaYvonne Nitschke, Department of Gener... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5241061 Mon, 19 Sep 2011 13:44:38 +0100 5241061 http://www.medworm.com/index.php?rid=5241062&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl7n7558667075418%2F Abstract  Barth syndrome (BTHS) is an X-linked disorder characterized by skeletal myopathy, neutropenia, growth delay, and cardiomyopathy. It is caused by mutations in the tafazzin gene (TAZ). Although early diagnosis is critical to prevent the progression of heart failure, this disease remains unrecognized when heart failure is not clinically significant. Here we report on a 13-year-old boy with no family history of BTHS who was diagnosed with the syndrome in the subclinical stage of heart failure. The clues to the diagnosis of BTHS in this patient were the findings of lipid storage myopathy in the skeletal muscle biopsy, elevated plasma brain natriuretic peptide, and the diagnosis of isolated noncompaction of the ventricular myocardium in echocardiography. Genetic studies ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5241062 Mon, 19 Sep 2011 13:44:37 +0100 5241062 http://www.medworm.com/index.php?rid=5241063&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4n43r137842101t5%2F Conclusion: Hypokalemic metabolic alkalosis is a rare manifestation in Dent disease. It is speculated that Dent patients with features of Bartter syndrome are susceptible to progression to renal failure. To study this hypothesis, additional observations and long-term follow-up of such patients are necessary. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00431-011-1578-3Authors Takayuki Okamoto, Department of Pediatrics, Hokkaido University Graduate School of Medicine, N15, W7, Sapporo, 060-8638 JapanToshihiro Tajima, Department of Pediatrics, Hokkaido University Graduate School of Medicine, N15, W7, Sapporo, 060-8638 JapanTomoya Hirayama, Department of Nephrology, Kitasaito Hospital, 9 Choume Miyashita Street, Asahikawa, 070-0030 JapanSatoshi Sasaki, Depart... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5241063 Mon, 19 Sep 2011 13:44:36 +0100 5241063 http://www.medworm.com/index.php?rid=5228749&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F978t5606823r17w2%2F In conclusion, this study shows the absence of effectiveness of CP using passive expiratory techniques in infants hospitalised for bronchiolitis. It seems justified to recommend against the routine use of CP in these patients. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1562-yAuthors Isabelle Rochat, Pediatric Pulmonology Unit, Children’s Hospital, University Hospitals, Geneva, SwitzerlandPatricia Leis, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandMarie Bouchardy, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandChristine Oberli, Pediatric Physiotherapy, Children’s Hospital, University Hospitals, Geneva, SwitzerlandHendrika Sourial, Pediatric Physiotherapy... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228749 Fri, 16 Sep 2011 16:42:43 +0100 5228749 http://www.medworm.com/index.php?rid=5228750&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F091777776p761468%2F Conclusion: The mutation c.485G> A in BMP4 might be one of the causes of human UPJO. Further functional studies are required to validate the association between this variation and UPJO. Otherwise, Id2 mutations do not seem to be involved in this disease. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1561-zAuthors Jun Li He, Ministry of Education Key Laboratory of Child Development and Disorders, Children’s Hospital of Chongqing Medical University, Chongqing, ChinaJun Hong Liu, Department of Urology, Children’s Hospital of Chongqing Medical University, 136 Zhongshan 2nd Road, Yuzhong District, Chongqing, 400014 ChinaFeng Liu, Department of Urology, Children’s Hospital of Chongqing Medical University, 136 Zhongshan 2nd Road, Yuzhong Distr... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228750 Fri, 16 Sep 2011 16:42:42 +0100 5228750 http://www.medworm.com/index.php?rid=5228751&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcu61651078720371%2F Abstract  Bleeding complications in children may be caused by disorders of secondary hemostasis or fibrinolysis. Characteristic features in medical history and physical examination, especially of hemophilia, are palpable deep hematomas, bleeding in joints and muscles, and recurrent bleedings. A detailed medical and family history combined with a thorough physical examination is essential to distinguish abnormal from normal bleeding and to decide whether it is necessary to perform diagnostic laboratory evaluation. Initial laboratory tests include prothrombin time and activated partial thromboplastin time. Knowledge of the classical coagulation cascade with its intrinsic, extrinsic, and common pathways, is useful to identify potential defects in the coagulation in order to de... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228751 Fri, 16 Sep 2011 06:01:10 +0100 5228751 http://www.medworm.com/index.php?rid=5228753&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu6371j7356743452%2F Abstract  Tracheal agenesis (TA) is a severe congenital disorder with often an unexpected emergency presentation. There is complete or partial absence of the trachea below the larynx, with presence or absence of a tracheoesophageal fistula (TOF). A neonate with TA is described, and another 48 cases found in literature are reviewed. Due to absence of a TOF, five cases were diagnosed prenatally because of congenital high airway obstruction syndrome (CHAOS). When a TOF is present, polyhydramnion and several other congenital malformations seen on the ultrasound examination should alert clinicians of potential tracheal problems. Prenatal magnetic resonance imaging (MRI) may provide a definitive diagnosis. Postnatal diagnosis is based on recognition of specific clinical signs in t... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228753 Wed, 14 Sep 2011 16:08:29 +0100 5228753 http://www.medworm.com/index.php?rid=5228752&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4534761q61272566%2F Conclusion: Patients with a mutation in the FOXC2 transcription factor usually show lower limb lymphedema with onset at or after puberty, together with distichiasis. However, the eye manifestations can be very mild and easily overlooked. The association between FOXC2 mutation and neonatal hydrops resulting in terminal respiratory failure is not reported so far. Therefore, in sporadic patients diagnosed with non-immune hydrops fetalis, lymphangiogenic genes should be systematically screened for mutations. In addition, all cases of fetal edema must prompt a thorough analysis of the familial pedigree, in order to detect familial patterns and to facilitate adequate antenatal counseling. Content Type Journal ArticleCategory Original PaperPages 1-4DOI 10.1007/s00431-011-1557-8Authors ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228752 Wed, 14 Sep 2011 16:08:29 +0100 5228752 http://www.medworm.com/index.php?rid=5228754&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgk3611552347vq50%2F Conclusions: Major concerns about the use of fluconazole prophylaxis include its efficacy, the risk of emergence of resistant species and the absence of clear consensus to support routine use. Future studies that address these issues will contribute to a more rational use of fluconazole prophylaxis. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00431-011-1565-8Authors Florentia Kaguelidou, Paediatric Pharmacology and Pharmacogenetics Department, APHP, Hôpital Robert Debré; INSERM CIC9202, Université Paris 7, Paris, FranceChiara Pandolfini, Laboratory for Mother and Child Health, Department of Public Health, ‘Mario Negri’ Pharmacological Research Institute, Milan, ItalyPaolo Manzoni, Neonatology and Hospital Neonatal Intensive Care Unit, Azienda Os... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228754 Tue, 13 Sep 2011 05:57:25 +0100 5228754 http://www.medworm.com/index.php?rid=5228755&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff86u705951286401%2F Conclusion: Macroglossia can occur even 3–5 days after surgery and can be maintained by the pressure of the endotracheal tube to the tongue ground. Knowledge and avoidance of these risk factors are as important as early treatment of respiratory compromise. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00431-011-1567-6Authors Shino Junghaenel, Department of Neonatology and Paediatric Intensive Care, University Hospital of Cologne, Children’s Hospital, Kerpener Str. 62, 50937 Cologne, GermanyTitus Keller, Department of Neonatology and Paediatric Intensive Care, University Hospital of Cologne, Children’s Hospital, Kerpener Str. 62, 50937 Cologne, GermanyRobert Mischkowski, Department of Craniomaxillofacial and Plastic Surgery, University Hospital ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228755 Tue, 13 Sep 2011 05:57:23 +0100 5228755 http://www.medworm.com/index.php?rid=5228756&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg080w813481pl62h%2F Conclusion: the prevalence of childhood obesity in Xi'an has become a concern, and sleeping time, sedentary behavior, and family factors have pronounced effects on the prevalence of obesity. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1566-7Authors Xiaoqing Yi, Department of Pediatrics, Second Hospital of Xi’an Jiaotong University, Xi’an, 710061 Shaanxi Province, People’s Republic of ChinaChunyan Yin, Department of Pediatrics, Second Hospital of Xi’an Jiaotong University, Xi’an, 710061 Shaanxi Province, People’s Republic of ChinaMing Chang, Department of Pediatrics, Central Hospital of Ankang, Ankang, 725000 Shaanxi Province, People’s Republic of ChinaYanfeng Xiao, Department of Pediatrics, Second Hospital of Xi’an Jiaotong Uni... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228756 Mon, 12 Sep 2011 15:50:09 +0100 5228756 http://www.medworm.com/index.php?rid=5228758&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp73p53504jx56478%2F Conclusion: Intrahepatic shunts may close spontaneously. Transcatheter embolization is effective for the treatment of symptomatic intrahepatic shunts. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1564-9Authors Myung Jin Kim, Department of Pediatrics, Seoul National University College of Medicine, Seoul, KoreaJae Sung Ko, Department of Pediatrics, Seoul National University College of Medicine, Seoul, KoreaJeong Kee Seo, Department of Pediatrics, Seoul National University College of Medicine, Seoul, KoreaHye Ran Yang, Department of Pediatrics, Seoul National University College of Medicine, Seoul, KoreaJu Young Chang, Department of Pediatrics, Seoul National University College of Medicine, Seoul, KoreaGi Beom Kim, Department of Pediatrics, Seoul N... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228758 Mon, 12 Sep 2011 15:50:08 +0100 5228758 http://www.medworm.com/index.php?rid=5228757&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy5l8184g62161n62%2F Abstract  The aim of this review is to give insight on the benefits and risks of vegetarianism, with special emphasis on vegetarian child nutrition. This eating pattern excluding meat and fish is being adopted by a growing number of people. A vegetarian diet has been shown to be associated with lower mortality of ischaemic heart disease and lower prevalence of obesity. Growth in children on a vegetarian diet including dairy has been shown to be similar to omnivorous peers. Although vegetarianism in adolescents is associated with eating disorders, there is no proof of a causal relation, as the eating disorder generally precedes the exclusion of meat from the diet. A well-balanced lacto-ovo-vegetarian diet, including dairy products, can satisfy all nutritional needs of the gr... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5228757 Mon, 12 Sep 2011 15:50:08 +0100 5228757 http://www.medworm.com/index.php?rid=5212637&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn78566014586n304%2F Conclusion: In children with DR-HD, NS is a safe rehydration fluid with a satisfactory rate of Na+ drop and relatively low incidence of morbidity and mortality. Judicious use of IVE should be exerted and closer monitoring should be guaranteed for children requiring large volumes for IVE and for those showing rapid initial drop of serum Na+ to avoid neurological complications and poor outcome. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1559-6Authors Mohammed A. El-Bayoumi, Pediatric Intensive Care Unit, Mansoura University Children Hospital, PO Box 63, Mansoura, EgyptAlaa M. Abdelkader, Pediatric Intensive Care Unit, Mansoura University Children Hospital, Al-Gomhuria Street, Mansoura, 35516, EgyptMohamed M. A. El-Assmy, Pediatric Intensive Car... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5212637 Fri, 09 Sep 2011 16:46:06 +0100 5212637 http://www.medworm.com/index.php?rid=5212638&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn2024u176067mx7u%2F Conclusion: In post BMT patients, our data demonstrated higher odds of moderate/severe sinusitis on CT scans associated with rhinorrhea, cough or nasal congestion. These finding suggest that in post BMT children, detailed sinus history may still play a vital role in the diagnosis of sinusitis. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s00431-011-1560-0Authors Sahayini Arulrajah, Neuroradiology, Department of Radiology and Radiological Science, Johns Hopkins Hospital, Baltimore, MD, USAHeather Symons, Sydney Kimmel Cancer Center, Department of Pediatrics and Oncology, Johns Hopkins Hospital, Baltimore, MD, USAElizabeth Khaykin Cahoon, Department of Mental Health, Johns Hopkins School of Public Health, Baltimore, MD, USAAylin Tekes, Pediatric Radiology,... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5212638 Fri, 09 Sep 2011 05:49:00 +0100 5212638 http://www.medworm.com/index.php?rid=5212639&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr07x77608401m050%2F Abstract  Cilia are antenna-like organelles found on the surface of most cells. They transduce molecular signals and facilitate interactions between cells and their environment. Ciliary dysfunction has been shown to underlie a broad range of overlapping, clinically and genetically heterogeneous phenotypes, collectively termed ciliopathies. Literally, all organs can be affected. Frequent cilia-related manifestations are (poly)cystic kidney disease, retinal degeneration, situs inversus, cardiac defects, polydactyly, other skeletal abnormalities, and defects of the central and peripheral nervous system, occurring either isolated or as part of syndromes. Characterization of ciliopathies and the decisive role of primary cilia in signal transduction and cell division provides nov... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5212639 Tue, 06 Sep 2011 08:54:21 +0100 5212639 http://www.medworm.com/index.php?rid=5198531&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb1391m4m70351r63%2F Content Type Journal ArticleCategory Images in PediatricsPages 1-1DOI 10.1007/s00431-011-1546-yAuthors Florian Ensat, Department of Plastic and Reconstructive Surgery, Krankenhaus der Barmherzigen Brüder, Teaching Hospital of the Paracelsus Medical University Salzburg, Kajetanerplatz 1, 5020 Salzburg, AustriaMonika Edelbauer, Department of Paediatrics, Innsbruck Medical University, Innsbruck, AustriaGottfried Wechselberger, Department of Plastic and Reconstructive Surgery, Krankenhaus der Barmherzigen Brüder, Teaching Hospital of the Paracelsus Medical University Salzburg, Kajetanerplatz 1, 5020 Salzburg, Austria Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5198531 Mon, 05 Sep 2011 16:16:20 +0100 5198531 http://www.medworm.com/index.php?rid=5186524&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3166m801817lu7vr%2F Conclusion: We believe that a combined approach, using a checklist with risk factors for CAN, a structured clinical assessment and inspection of the undressed patient (called ‘top–toe’ inspection) and a system of standard referral of all children from parents who attend the ER because of alcohol or drugs intoxication, severe psychiatric disorders or with injuries due to intimate partner violence, is the most promising procedure for the early diagnosis of CAN in the ER setting. Content Type Journal ArticleCategory ReviewPages 1-9DOI 10.1007/s00431-011-1551-1Authors Arianne Hélène Teeuw, Department of Social Paediatrics, Emma Children’s Hospital, Academic Medical Centre, P.O. Box 22660, 1100 DD, Amsterdam, the NetherlandsBert H. F. Derkx, Department of Social Paediatrics,... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5186524 Wed, 31 Aug 2011 15:56:14 +0100 5186524 http://www.medworm.com/index.php?rid=5171689&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc572587772105k28%2F Conclusions: The WHO guidelines for interpretation of chest radiographs result in high level of agreement between readers for the definition of “alveolar pneumonia” and “no pneumonia” but poor agreement for non-alveolar pneumonia. The disagreement with regard to the latter was associated with overdiagnosis by pediatricians, which may lead to overtreatment. We believe that radiographic non-alveolar pneumonia should not be an endpoint for clinical trials and research, nor should it be implemented in clinical setting. Content Type Journal ArticleCategory Original PaperPages 1-6DOI 10.1007/s00431-011-1543-1Authors Shalom Ben Shimol, Pediatric Infectious Disease Unit, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5171689 Thu, 25 Aug 2011 15:49:57 +0100 5171689 http://www.medworm.com/index.php?rid=5165051&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft0q11w7736k37015%2F Conclusion: Although the incidence of ARF has decreased in the last decade, it still continues to be an important public health problem in Turkish pediatric population. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s00431-011-1555-xAuthors Utku Arman Örün, Pediatric Cardiology Department, Dr. Sami Ulus Children’s Hospital, Babur Street, 44(06080) Altındag, Ankara, TurkeyÖzben Ceylan, Pediatric Cardiology Department, Dr. Sami Ulus Children’s Hospital, Babur Street, 44(06080) Altındag, Ankara, TurkeyMeki Bilici, Pediatric Cardiology Department, Fatih University School of Medicine, Ankara, TurkeySelmin Karademir, Pediatric Cardiology Department, Dr. Sami Ulus Children’s Hospital, Babur Street, 44(06080) Altındag, Ankara, TurkeyBurhan Öcal, Pediat... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5165051 Wed, 24 Aug 2011 16:01:55 +0100 5165051 http://www.medworm.com/index.php?rid=5149189&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F862666u202406764%2F We report control values for healthy children between 0 and 18 years and investigated the feasibility of this technique in a pediatric population. For control values, TE was performed in infants and children after exclusion of liver disease by medical history, clinical examination, blood investigation, and abdominal ultrasound. For feasibility analyses the results of all TE performed in our clinic were analyzed irrespective of the underlying disease. Liver stiffness was measured with the S-probe (thorax diameter <45 cm (S1) or 45–75 cm (S2)) and the M-probe (thorax diameter >75 cm) according to the manufacturer’s recommendations. A total of 240 healthy children were analyzed to establish control values. The median liver stiffness was 4.7 kPa resulti... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5149189 Mon, 22 Aug 2011 15:59:10 +0100 5149189 http://www.medworm.com/index.php?rid=5149190&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa4026011nr512k29%2F Content Type Journal ArticleCategory Editorial CommentPages 1-2DOI 10.1007/s00431-011-1545-zAuthors Jose Ramet, Department of Pediatrics, University of Antwerp & Antwerp University Hospital, Antwerp, Belgium Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5149190 Wed, 17 Aug 2011 05:55:22 +0100 5149190 http://www.medworm.com/index.php?rid=5149191&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd20948640x3v4275%2F We describe a male infant first admitted at 17 days old for necrotizing enteritis complicated by cardiac and renal failure. Because of progressive renal function deterioration, a renal biopsy was performed at 8 months old, and histopathologic examination was compatible with renal venous thrombosis. Laboratory searching for vascular, prothrombotic, and metabolic disease was negative. Five months later, he developed two different episodes (20-day range) of ischemic stroke. Genetic test for thrombophilic conditions was positive for two different mutations, and repeatedly high titers of lupus anticoagulant, anticardiolipin, and anti-β2glicoprotein I antibodies were found. He was treated successfully with anticoagulants and showed a favorable clinical evolution. To the best of ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5149191 Tue, 16 Aug 2011 06:14:30 +0100 5149191 http://www.medworm.com/index.php?rid=5149192&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv8k22283l0r41gv5%2F Conclusion: This rare association required an exceptional therapeutic approach: combined simultaneous orthotopic liver and kidney transplantation in a situs inversus recipient. The long-term follow-up was excellent with a very good evolution of the renal and hepatic grafts and normalization of growth and weight. This malformation complex has an autosomal recessive inheritance with a 25% recurrence risk in each pregnancy. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s00431-011-1552-0Authors Ana-Maria Calinescu-Tuleasca, Service of Pediatric Surgery, University Hospitals of Geneva, 6 Rue Willy Donzé, 1205 Geneva, SwitzerlandArmand Bottani, Service of Genetic Medicine, University Hospitals of Geneva, 1 Michel Servet, 1211 Geneva, SwitzerlandAnne-Laure Rou... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5149192 Tue, 16 Aug 2011 06:14:29 +0100 5149192 http://www.medworm.com/index.php?rid=5134250&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr77t713803327u44%2F Conclusion: Pediatric tick-borne CNS infections are unexpectedly common and should be considered in children with unspecific and unexplained acute CNS-related symptoms. Content Type Journal ArticlePages 1-6DOI 10.1007/s00431-011-1542-2Authors Mikael Sundin, Division of Pediatrics, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet at Karolinska University Hospital, 141 86 Stockholm, SwedenMagnus E. A. Hansson, Division of Pediatrics, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet at Karolinska University Hospital, 141 86 Stockholm, SwedenMona-Lisa Engman, Division of Pediatrics, Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet at Karolinska University ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5134250 Sat, 13 Aug 2011 06:14:55 +0100 5134250 http://www.medworm.com/index.php?rid=5127769&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb6775561x7375517%2F Conclusions: hypernatremia is a specific complication of RV+ AGE. RV would therefore appear to be the cause of infant toxicosis, the traditional descriptive term for severe dehydration and clinical deterioration following AGE. Content Type Journal ArticlePages 1-9DOI 10.1007/s00431-011-1536-0Authors Petra Kaiser, Prof. Hess Kinderklinik, Klinikum Bremen-Mitte, St. Juergen-Strasse, 28205 Bremen, GermanyMichael Borte, Kinderklinik, Klinikum St. Georg gGmbH Leipzig, Leipzig, GermanyKlaus-Peter Zimmer, Universitätskinderklinik Giessen, Giessen, GermanyHans-Iko Huppertz, Prof. Hess Kinderklinik, Klinikum Bremen-Mitte, St. Juergen-Strasse, 28205 Bremen, Germany Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5127769 Thu, 11 Aug 2011 05:55:11 +0100 5127769 http://www.medworm.com/index.php?rid=5127772&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1w431753tn8r6u34%2F Conclusion Establishing the diagnosis of congenital adrenal disorders is essential in a baby who develops a salt-losing crisis in the first few weeks of life. However, pyelonephritis should be considered and can be rapidly excluded in any infant presenting with a salt-losing crisis with hyponatremia and hyperkalaemia, in particular, outside the neonatal period. Only then should an endocrine cause for this presentation be considered and treatment commenced. Content Type Journal ArticlePages 1-5DOI 10.1007/s00431-011-1541-3Authors Bharathi Pai, Department of Endocrinology and Diabetes, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham, B4 6NH UKNick Shaw, Department of Endocrinology and Diabetes, Birmingham Children’s Hospital, Steelhouse Lane, Birmingham, B4 6NH UKWo... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5127772 Thu, 11 Aug 2011 05:55:10 +0100 5127772 http://www.medworm.com/index.php?rid=5127771&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F14hq7q6k68327561%2F Conclusion: Mortality and neurodisability at follow-up were common in infants born at term without major congenital anomalies who required mechanical ventilation in the first 24 h after birth, particularly in those who developed seizures requiring treatment and prolonged ventilation. Content Type Journal ArticlePages 1-6DOI 10.1007/s00431-011-1549-8Authors Ghada Ramadan, Neonatal Intensive Care Unit, King’s College Hospital, London, UKNicola Paul, Neonatal Intensive Care Unit, King’s College Hospital, London, UKMargaret Morton, Child Development Centre, Southwark Primary Care Trust, London, UKJanet L. Peacock, Division of Health and Social Care Research, King’s College London, London, UKAnne Greenough, Division of Asthma, Allergy & Lung Biology, MRC-Asthma UK Centre in ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5127771 Thu, 11 Aug 2011 05:55:10 +0100 5127771 http://www.medworm.com/index.php?rid=5127770&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr70174w68813r2x4%2F We describe the institution of a purpose-designed bundle of care in a tertiary paediatric ICU based on the available literature as part of our hospital’s transformation project into reducing health-care-associated infection. A nurse-led VAP surveillance programme is in place, and we used this to compare VAP incidence before and after commencing a series of care measures aimed at reducing VAP as part of an overall drive for patient safety. The diagnostic criteria, surveillance methods and rates of VAP (5.6 per 1,000 ventilator days) have been previously reported. Nurse educators were added to the original core group, as a key feature is buy in from nursing staff. All nursing staff had multiple training opportunities, and VAP project education became a routine part of staff inductio... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5127770 Thu, 11 Aug 2011 05:55:10 +0100 5127770 http://www.medworm.com/index.php?rid=5112353&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa2r4374617q1t418%2F Conclusion: Septic encephalopathy with hypoxic–ischemic encephalopathy can be a serious complication in severe sepsis. It is unknown to what extent the mutant SOX10 protein influenced the degree of brain injury—for example central nervous system susceptibility to hypoxia—during sepsis, which may explain the severe encephalopathy with clinical signs of PVS the boy developed. Content Type Journal ArticlePages 1-6DOI 10.1007/s00431-011-1539-xAuthors Alexandra Unzicker, Children’s Hospital, University of Würzburg, Josef-Schneider-Strasse 2, 97080 Würzburg, GermanyVeronique Pingault, AP-HP (Assistance Publique des Hopitaux de Paris), GROUPE HOSPITALIER Henri Mondor, Service de Biochimie et Genetique, Creteil, FranceThomas Meyer, Pediatric Surgery Unit, University of Würzburg... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5112353 Sat, 06 Aug 2011 05:59:34 +0100 5112353 http://www.medworm.com/index.php?rid=5104296&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk33t07h6461315gg%2F Abstract  Reflex vagal hypertonia (RVH) has been identified as a possible cause of sudden unexpected death in infants during the first year of life. Homatropine methylbromide (HM) is an anticholinergic drug known to inhibit muscarinic acetylcholine receptors, thus affecting the parasympathetic nervous system. The aim of the present study was to investigate the effects of HM on 24-h Holter electrocardiographic signs of RVH (pre-HM treatment vs post-HM treatment; post-HM treatment vs a control group of healthy infants). A total of 50 patients (mean age, 6.1 ± 2.7 months; 28 males, 22 females; 12 born pre-term) affected by RVH were enrolled in the study. Pre-HM treatment vs post-HM treatment: statistically significant differences were detected for higher heart rate, ... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5104296 Thu, 04 Aug 2011 15:31:51 +0100 5104296 http://www.medworm.com/index.php?rid=5099455&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu0m8602115562767%2F We report our experience with aerosolized colistin in two preterm and one term neonate with Acinetobacter baumannii and Pseudomonas aeruginosa-related VAP who were unresponsiveness to previous antimicrobial treatment. All pathogens were isolated from tracheal aspirate. We used 5 mg/kg (base activity) aerosolized colistin methanesulfonate sodium in every 12 h as an adjunctive therapy for VAP. VAP was treated by 14, 14, and 16-day courses of aerosolized colistin in these patients, respectively. No adverse effect such as nephrotoxicity or neurotoxicity was observed. We found that aerosolized colistin was tolerable and safe, and it may be an adjunctive treatment option for MDR gram-negative bacterial VAP in neonates. Further studies are needed to determine appropriate doses for... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5099455 Tue, 02 Aug 2011 06:14:51 +0100 5099455 http://www.medworm.com/index.php?rid=5099456&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3v274t1u252t5l87%2F Abstract  Omalizumab is currently used in severe asthma and has been tried in other allergic disorders. The authors report two patients with multiple food allergies and eosinophilic esophagitis on a very restrictive diet who have been treated with omalizumab, in order to improve food intolerance—the major distressing factor in their lives. The patients significantly improved in the reported symptoms. However, no improvement was seen regarding esophageal endoscopy and histology. Given the poor histological and endoscopy response, eosinophilic esophagitis persistence is unlikely to be IgE dependent. Omalizumab may improve the quality of life of patients with severe food allergy by improving symptoms, but it does not appear to change endoscopic and histological features of e... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5099456 Tue, 02 Aug 2011 06:14:49 +0100 5099456 http://www.medworm.com/index.php?rid=5082223&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0r02744357113m6l%2F Abstract  Mucocutaneous bleeding is common in childhood and may be the result of primary hemostatic disorders such as vascular abnormalities, von Willebrand disease, thrombocytopenia, and platelet dysfunction. A detailed bleeding history and physical examination are essential to distinguish between normal and abnormal bleeding and to decide whether it is necessary to perform further laboratory evaluation. Initial laboratory tests include complete blood count, peripheral blood smear, mean platelet volume, von Willebrand factor (VWF) antigen assay, VWF ristocetin cofactor activity, and factor VIII activity. Once thrombocytopenia and von Willebrand disease have been excluded, platelet function should be tested by platelet aggregation. Additional specific diagnostic tests, such... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5082223 Thu, 28 Jul 2011 15:53:42 +0100 5082223 http://www.medworm.com/index.php?rid=5082222&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F88688h782m82t873%2F The objective of this study is to detect the presence of EGFR in cases of acquired cholesteatoma of the middle ear and correlate the expression of this receptor with patients’ ages. In this cross-sectional study, cholesteatoma samples were collected from 50 patients (35 adults and 15 children) who underwent otological surgery, throughout 1 year of study. These samples were subjected to histological and immunohistochemical assays. Results were submitted to statistical analyses and main findings were: EGFR was present in the parabasal layers in 27 cases and EGFR expression was extended to all layers of the matrix in 17 cases. There were no statistically significant differences in what concerns age-related variances in EGFR expression. The intensity and location of EGFR expressio... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5082222 Thu, 28 Jul 2011 15:53:42 +0100 5082222 http://www.medworm.com/index.php?rid=5058666&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5388q47u1026x013%2F In conclusion, the recent advances made in understanding the underlying pathogeneses of the various forms of rickets has helped to delineate the diagnostic tests that assist in the diagnosis and management of the disease in children. Content Type Journal ArticlePages 1-8DOI 10.1007/s00431-011-1529-zAuthors Jaishen Rajah, Department of Pediatrics, Sheikh Khalifa Medical City, Abu Dhabi, United Arab EmiratesKebashni Thandrayen, MRC/Wits Mineral Metabolism Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South AfricaJohn M. Pettifor, MRC/Wits Mineral Metabolism Research Unit, Department of Paediatrics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa Journal European Jour... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5058666 Thu, 21 Jul 2011 18:04:41 +0100 5058666 http://www.medworm.com/index.php?rid=5058665&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6727u134t4022v25%2F Conclusion: Given the considerable clinical overlaps between the 22q11.2 deletion syndrome and clinical manifestation of the patient described in this study, we propose that region 4q34.1–q35.2 should be considered as another region associated with phenotype resembling 22q11.2 deletion syndrome. We also propose that distal 4q deletions should be considered in the evaluation of patients with phenotypic manifestations resembling 22q11.2 deletion syndrome in whom no 22q11.2 microdeletion was detected, even in the absence of distinctive fifth finger anomalies. Additionally, we underline the importance of applying array CGH that enables simultaneous genome-wide detection and delineation of copy number changes (e.g., deletions and duplications). Content Type Journal ArticlePages 1-6D... European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5058665 Thu, 21 Jul 2011 18:04:41 +0100 5058665 http://www.medworm.com/index.php?rid=5058667&cid=s_33425_33_f&fid=33425&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm4r673n717261218%2F Content Type Journal ArticlePages 1-1DOI 10.1007/s00431-011-1535-1Authors Matti Korppi, Pediatric Research Center, Tampere University and University Hospital, 33014 Tampere, Finland Journal European Journal of PediatricsOnline ISSN 1432-1076Print ISSN 0340-6199 (Source: European Journal of Pediatrics) European Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=5058667 Tue, 19 Jul 2011 23:44:52 +0100 5058667